Essential role of caveolae in interleukin-6- and insulin-like growth factor I-triggered Akt-1-mediated survival of multiple myeloma cells

Journal of Biological Chemistry

Volumn 278, Issue 8, 2003, Pages 5794-5801

  Podar, Klaus ^a   Tai, Yu Tzu ^a   Cole, Craig E ^a,b   Hideshima, Teru ^a   Sattler, Martin ^a   Hamblin, Angela ^a   Mitsiades, Nicholas ^a   Schlossman, Robert L ^a   Davies, Faith E ^c   Morgan, Gareth J ^c   Munshi, Nikhil C ^a,d   Chauhan, Dharminder ^a   Anderson, Kenneth C ^a,e  

^a HARVARD MEDICAL SCHOOL   (United States)

^b UNIVERSITY OF MICHIGAN   (United States)

^c LEEDS GENERAL INFIRMARY   (United Kingdom)

^d VETERANS AFFAIRS MEDICAL CENTER   (United States)

^e DANA FARBER CANCER INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BIOLOGICAL MEMBRANES; CHOLESTEROL; LIPIDS; TRANSMISSION ELECTRON MICROSCOPY;

PLASMA MEMBRANES;

BIOCHEMISTRY;

BETA CYCLODEXTRIN; CAVEOLIN 1; CHOLESTEROL; GLYCOPROTEIN GP 130; INTERLEUKIN 6; INTERLEUKIN 6 RECEPTOR; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN KINASE B; SOMATOMEDIN C; AKT1 PROTEIN, HUMAN; ONCOPROTEIN; PROTEIN SERINE THREONINE KINASE; RECOMBINANT PROTEIN;

ARTICLE; CANCER CELL CULTURE; CAVEOLA; CELL GROWTH; CELL MEMBRANE; CELL SURVIVAL; CELLULAR DISTRIBUTION; CONTROLLED STUDY; HUMAN; HUMAN CELL; MULTIPLE MYELOMA; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; PROTEIN PHOSPHORYLATION; TRANSMISSION ELECTRON MICROSCOPY; CELL CULTURE; DRUG EFFECT; IMMUNOLOGY; METABOLISM; PATHOLOGY; PHYSIOLOGY; SIGNAL TRANSDUCTION;

CAVEOLAE; CELL SURVIVAL; CHOLESTEROL; HUMANS; INSULIN-LIKE GROWTH FACTOR I; INTERLEUKIN-6; MULTIPLE MYELOMA; PROTEIN-SERINE-THREONINE KINASES; PROTO-ONCOGENE PROTEINS; PROTO-ONCOGENE PROTEINS C-AKT; RECOMBINANT PROTEINS; SIGNAL TRANSDUCTION; TUMOR CELLS, CULTURED;

EID: 0037458621     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M208636200     Document Type: Article

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