메뉴 건너뛰기




Volumn 286, Issue 1 49-1, 2004, Pages

Anti-inflammatory effect of two isoforms of COX in H. pylori-induced gastritis in mice: Possible involvement of PGE2

Author keywords

Gastric mucosal integrity; Neutrophil; Tumor necrosis factor

Indexed keywords

5 (4 CHLOROPHENYL) 1 (4 METHOXYPHENYL) 3 TRIFLUOROMETHYL 1H PYRAZOLE; CYCLOOXYGENASE 1; CYCLOOXYGENASE 1 INHIBITOR; CYCLOOXYGENASE 2; CYCLOOXYGENASE 2 INHIBITOR; INDOMETACIN; ISOENZYME; MESSENGER RNA; MYELOPEROXIDASE; N (2 CYCLOHEXYLOXY 4 NITROPHENYL)METHANESULFONAMIDE; PROSTAGLANDIN E2; PROSTAGLANDIN SYNTHASE; TUMOR NECROSIS FACTOR ALPHA;

EID: 9144230729     PISSN: 01931857     EISSN: None     Source Type: Journal    
DOI: 10.1152/ajpgi.00137.2003     Document Type: Article
Times cited : (31)

References (49)
  • 1
    • 0025767642 scopus 로고
    • Gastroduodenal mucosal prostaglandin generation in patients with Helicobacter pylori before and after treatment with bismuth subsalicylate
    • Avunduk C, Suliman M, Gang D, Polakowski N, Eastwood GL. Gastroduodenal mucosal prostaglandin generation in patients with Helicobacter pylori before and after treatment with bismuth subsalicylate. Dig Dis Sci 36: 431-434, 1991.
    • (1991) Dig Dis Sci , vol.36 , pp. 431-434
    • Avunduk, C.1    Suliman, M.2    Gang, D.3    Polakowski, N.4    Eastwood, G.L.5
  • 2
    • 0036122473 scopus 로고    scopus 로고
    • Selective cyclooxygenase-2 blocker delays healing of esophageal ulcers in rats and inhibits ulceration-triggered c-Met/hepatocyte growth factor receptor induction and extracellular signal-regulated kinase 2 activation
    • Baatar D, Jones MK, Pai R, Kawanaka H, Szabo IL, Moon WS, Kitano S, and Tarnawski AS. Selective cyclooxygenase-2 blocker delays healing of esophageal ulcers in rats and inhibits ulceration-triggered c-Met/hepatocyte growth factor receptor induction and extracellular signal-regulated kinase 2 activation. Am J Pathol 160: 963-972, 2002.
    • (2002) Am J Pathol , vol.160 , pp. 963-972
    • Baatar, D.1    Jones, M.K.2    Pai, R.3    Kawanaka, H.4    Szabo, I.L.5    Moon, W.S.6    Kitano, S.7    Tarnawski, A.S.8
  • 3
    • 0007414682 scopus 로고    scopus 로고
    • Cyclooxygenase-2 selective inhibitors aggravate kainic acid induced seizure and neuronal cell death in the hippocampus
    • Baik EJ, Kim EJ, Lee SH, and Moon C. Cyclooxygenase-2 selective inhibitors aggravate kainic acid induced seizure and neuronal cell death in the hippocampus. Brain Res 843: 118-129, 1999.
    • (1999) Brain Res , vol.843 , pp. 118-129
    • Baik, E.J.1    Kim, E.J.2    Lee, S.H.3    Moon, C.4
  • 5
    • 0036129346 scopus 로고    scopus 로고
    • Effects of selective cyclooxygenase-2 inhibitor and non-selective NSAIDs on Helicobacter pylori-induced gastritis in Mongolian gerbils
    • Bhang CS, Lee HS, Kim SS, Song HJ, Sung YJ, Kim JI, Chung IS, Sun HS, Park Dh, and Lee YS. Effects of selective cyclooxygenase-2 inhibitor and non-selective NSAIDs on Helicobacter pylori-induced gastritis in Mongolian gerbils. Helicobacter 7: 14-21, 2002.
    • (2002) Helicobacter , vol.7 , pp. 14-21
    • Bhang, C.S.1    Lee, H.S.2    Kim, S.S.3    Song, H.J.4    Sung, Y.J.5    Kim, J.I.6    Chung, I.S.7    Sun, H.S.8    Park, Dh.9    Lee, Y.S.10
  • 6
    • 0020051148 scopus 로고
    • Measurement of cutaneous inflammation: Estimation of neutrophil content with an enzyme marker
    • Bradley PP, Priebat DA, Christensen RD, and Rothstein G. Measurement of cutaneous inflammation: estimation of neutrophil content with an enzyme marker. J Invest Dermatol 78: 206-209, 1982.
    • (1982) J Invest Dermatol , vol.78 , pp. 206-209
    • Bradley, P.P.1    Priebat, D.A.2    Christensen, R.D.3    Rothstein, G.4
  • 7
    • 0037021982 scopus 로고    scopus 로고
    • Eradication of Helicobacter pylori and risk of peptic ulcers in patients starting long-term treatment with non-steroidal anti-inflammatory drugs: A randomised trial
    • Chan FK, To KF, Wu JC, Yung MY, Leung WK, Kwok T, Hui Y, Chan HL, Chan CS, Hui E, Woo J, and Sung JJ. Eradication of Helicobacter pylori and risk of peptic ulcers in patients starting long-term treatment with non-steroidal anti-inflammatory drugs: a randomised trial. Lancet 359: 9-13, 2002.
    • (2002) Lancet , vol.359 , pp. 9-13
    • Chan, F.K.1    To, K.F.2    Wu, J.C.3    Yung, M.Y.4    Leung, W.K.5    Kwok, T.6    Hui, Y.7    Chan, H.L.8    Chan, C.S.9    Hui, E.10    Woo, J.11    Sung, J.J.12
  • 8
    • 0025885785 scopus 로고
    • Mucosal tumour necrosis factor-α and interleukin-6 in patients with Helicobacter pylori associated gastritis
    • Crabtree JE, Shallcross TM, Heatley RV, and Wyatt JI. Mucosal tumour necrosis factor-α and interleukin-6 in patients with Helicobacter pylori associated gastritis. Gut 32: 1473-1477, 1991.
    • (1991) Gut , vol.32 , pp. 1473-1477
    • Crabtree, J.E.1    Shallcross, T.M.2    Heatley, R.V.3    Wyatt, J.I.4
  • 9
    • 0028200445 scopus 로고
    • Pathophysiology of Helicobacter pylori infection
    • Dixon MF. Pathophysiology of Helicobacter pylori infection. Scand J Gastroenterol 201, Suppl: 7-10, 1994.
    • (1994) Scand J Gastroenterol , vol.201 , Issue.SUPPL. , pp. 7-10
    • Dixon, M.F.1
  • 10
    • 0034972193 scopus 로고    scopus 로고
    • Role of Helicobacter pylori infection in gastroduodenal injury and gastric prostaglandin synthesis during long term/low dose aspirin therapy: A prospective placebo-controlled, double-blind randomized trial
    • Feldman M, Cryer B, Mallat D, and Go MF. Role of Helicobacter pylori infection in gastroduodenal injury and gastric prostaglandin synthesis during long term/low dose aspirin therapy: a prospective placebo-controlled, double-blind randomized trial. Am J Gastroenterol 96: 1751-1757, 2001.
    • (2001) Am J Gastroenterol , vol.96 , pp. 1751-1757
    • Feldman, M.1    Cryer, B.2    Mallat, D.3    Go, M.F.4
  • 11
    • 0032995903 scopus 로고    scopus 로고
    • Increased expression and cellular localization of inducible nitric oxide synthase and cyclooxygenase 2 in Helicobacter pylori gastritis
    • Fu S, Ramanujam KS, Wong A, Fantry GT, Drachenberg CB, James SP, Meltzer SJ, and Wilson KT. Increased expression and cellular localization of inducible nitric oxide synthase and cyclooxygenase 2 in Helicobacter pylori gastritis. Gastroenterology 116: 1319-1329, 1999.
    • (1999) Gastroenterology , vol.116 , pp. 1319-1329
    • Fu, S.1    Ramanujam, K.S.2    Wong, A.3    Fantry, G.T.4    Drachenberg, C.B.5    James, S.P.6    Meltzer, S.J.7    Wilson, K.T.8
  • 13
    • 0031881410 scopus 로고    scopus 로고
    • Differential effects of inhibition of isoforms of cyclooxygenase (COX-1, COX-2) in chronic inflammation
    • Gilroy DW, Tomlinson A, and Willoughby DA. Differential effects of inhibition of isoforms of cyclooxygenase (COX-1, COX-2) in chronic inflammation. Inflamm Res 47: 79-85, 1998.
    • (1998) Inflamm Res , vol.47 , pp. 79-85
    • Gilroy, D.W.1    Tomlinson, A.2    Willoughby, D.A.3
  • 14
    • 0031932549 scopus 로고    scopus 로고
    • Cyclo-oxygenase-2 inhibitors and their influence on the protective effect of a mild irritant in the rat stomach
    • Gretzer B, Ehrlich K, Maricic N, Lambrecht N, Respondek M, and Peskar BM. Cyclo-oxygenase-2 inhibitors and their influence on the protective effect of a mild irritant in the rat stomach. Br J Pharmacol 123: 927-935, 1998.
    • (1998) Br J Pharmacol , vol.123 , pp. 927-935
    • Gretzer, B.1    Ehrlich, K.2    Maricic, N.3    Lambrecht, N.4    Respondek, M.5    Peskar, B.M.6
  • 15
    • 0033676255 scopus 로고    scopus 로고
    • Cyclooxygenase (COX) 1 and 2 in normal, inflamed, and ulcerated human gastric mucosa
    • Jackson LM, Wu KC, Mahida YR, Jenkins D, and Hawkey CJ. Cyclooxygenase (COX) 1 and 2 in normal, inflamed, and ulcerated human gastric mucosa. Gut 47: 762-770, 2000.
    • (2000) Gut , vol.47 , pp. 762-770
    • Jackson, L.M.1    Wu, K.C.2    Mahida, Y.R.3    Jenkins, D.4    Hawkey, C.J.5
  • 16
    • 0030668211 scopus 로고    scopus 로고
    • Increase in proliferation and apoptosis of gastric epithelial cells early in the natural history of Helicobacter pylori infection
    • Jones NL, Shannon PT, Cutz E, Yeger H, and Sherman PM. Increase in proliferation and apoptosis of gastric epithelial cells early in the natural history of Helicobacter pylori infection. Am J Pathol 151: 1695-1703, 1997.
    • (1997) Am J Pathol , vol.151 , pp. 1695-1703
    • Jones, N.L.1    Shannon, P.T.2    Cutz, E.3    Yeger, H.4    Sherman, P.M.5
  • 17
    • 0034121667 scopus 로고    scopus 로고
    • Comparison of the effect of rofecoxib (a cyclooxygenase 2 inhibitor), ibuprofen, and placebo on the gastroduodenal mucosa of patients with osteoarthritis: A randomized, double-blind, placebo-controlled trial
    • The Rofecoxib Osteoarthritis Endoscopy Multinational Study Group
    • Hawkey C, Laine L, Simon T, Beaulieu A, Maldonado-Cocco J, Acevedo E, Shahane A, Quan H, Bolognese J, and Mortensen E. Comparison of the effect of rofecoxib (a cyclooxygenase 2 inhibitor), ibuprofen, and placebo on the gastroduodenal mucosa of patients with osteoarthritis: a randomized, double-blind, placebo-controlled trial. The Rofecoxib Osteoarthritis Endoscopy Multinational Study Group. Arthritis Rheum 43: 370-377, 2000.
    • (2000) Arthritis Rheum , vol.43 , pp. 370-377
    • Hawkey, C.1    Laine, L.2    Simon, T.3    Beaulieu, A.4    Maldonado-Cocco, J.5    Acevedo, E.6    Shahane, A.7    Quan, H.8    Bolognese, J.9    Mortensen, E.10
  • 18
    • 0027309070 scopus 로고
    • Effect of Helicobacter pylori colonisation on gastric mucosal eicosanoid synthesis in patients taking non-steroidal anti-inflammatory drugs
    • Hudson N, Balsitis M, Filipowicz F, and Hawkey CJ. Effect of Helicobacter pylori colonisation on gastric mucosal eicosanoid synthesis in patients taking non-steroidal anti-inflammatory drugs. Gut 34: 748-751, 1993.
    • (1993) Gut , vol.34 , pp. 748-751
    • Hudson, N.1    Balsitis, M.2    Filipowicz, F.3    Hawkey, C.J.4
  • 19
    • 0033959528 scopus 로고    scopus 로고
    • Apoptosis of human gastric epithelial cells via caspase-3 activation in response to Helicobacter pylori infection: Possible involvement of neutrophils through tumor necrosis factor-α and soluble Fas ligands
    • Kim JM, Kim JS, Jung HC, Song IS, and Kim CY. Apoptosis of human gastric epithelial cells via caspase-3 activation in response to Helicobacter pylori infection: possible involvement of neutrophils through tumor necrosis factor-α and soluble Fas ligands. Scand J Gastroenterol 35: 40-48, 2000.
    • (2000) Scand J Gastroenterol , vol.35 , pp. 40-48
    • Kim, J.M.1    Kim, J.S.2    Jung, H.C.3    Song, I.S.4    Kim, C.Y.5
  • 20
    • 0034916387 scopus 로고    scopus 로고
    • Effects of nonsteroidal anti-inflammatory drugs on Helicobacter pylori-infected gastric mucosae of mice: Apoptosis, cell proliferation, and inflammatory activity
    • Kim TI, Lee YC, Lee KH, Han JH, Chon CY, Moon YM, Kang JK, and Park IS. Effects of nonsteroidal anti-inflammatory drugs on Helicobacter pylori-infected gastric mucosae of mice: apoptosis, cell proliferation, and inflammatory activity. Infect Immun 69: 5056-5063, 2001.
    • (2001) Infect Immun , vol.69 , pp. 5056-5063
    • Kim, T.I.1    Lee, Y.C.2    Lee, K.H.3    Han, J.H.4    Chon, C.Y.5    Moon, Y.M.6    Kang, J.K.7    Park, I.S.8
  • 21
    • 0021742157 scopus 로고
    • Quantitative assay for acute intestinal inflammation based on myeloperoxidase activity. Assessment of inflammation in rat and hamster models
    • Krawisz JE, Sharon P, and Stenson WF. Quantitative assay for acute intestinal inflammation based on myeloperoxidase activity. Assessment of inflammation in rat and hamster models. Gastroenterology 87: 1344-1350, 1984.
    • (1984) Gastroenterology , vol.87 , pp. 1344-1350
    • Krawisz, J.E.1    Sharon, P.2    Stenson, W.F.3
  • 26
    • 0033451177 scopus 로고    scopus 로고
    • COX2 inhibitors. A new class of antiangiogenic agents
    • Masferrer JL, Koki A and Seibert K. COX2 inhibitors. A new class of antiangiogenic agents. Ann NY Acad Sci 889: 84-86, 1999.
    • (1999) Ann NY Acad Sci , vol.889 , pp. 84-86
    • Masferrer, J.L.1    Koki, A.2    Seibert, K.3
  • 28
    • 0034076591 scopus 로고    scopus 로고
    • Association of gastric epithelial apoptosis with the ability of Helicobacter pylori to induce a neutrophil oxidative burst
    • Mizuki I, Shimoyama T, Fukuda S, Liu Q, Nakaji S, and Munakata A. Association of gastric epithelial apoptosis with the ability of Helicobacter pylori to induce a neutrophil oxidative burst. J Med Microbiol 49: 521-524, 2000.
    • (2000) J Med Microbiol , vol.49 , pp. 521-524
    • Mizuki, I.1    Shimoyama, T.2    Fukuda, S.3    Liu, Q.4    Nakaji, S.5    Munakata, A.6
  • 29
    • 0031052116 scopus 로고    scopus 로고
    • Induction of cyclooxygenase 2 in gastric mucosal lesions and its inhibition by the specific antagonist delays healing in mice
    • Mizuno H, Sakamoto C, Matsuda K, Wada K, Uchida T, Noguchi H, Akamatsu T, and Kasuga M. Induction of cyclooxygenase 2 in gastric mucosal lesions and its inhibition by the specific antagonist delays healing in mice. Gastroenterology 112: 387-397, 1997.
    • (1997) Gastroenterology , vol.112 , pp. 387-397
    • Mizuno, H.1    Sakamoto, C.2    Matsuda, K.3    Wada, K.4    Uchida, T.5    Noguchi, H.6    Akamatsu, T.7    Kasuga, M.8
  • 30
    • 0034114830 scopus 로고    scopus 로고
    • Wound collagen deposition in rats: Effects of an NO-NSAID and a selective COX-2 inhibitor
    • Muscara MN, McKnight W, Asfaha S, and Wallace JL. Wound collagen deposition in rats: effects of an NO-NSAID and a selective COX-2 inhibitor. Br J Pharmacol 129: 681-686, 2000.
    • (2000) Br J Pharmacol , vol.129 , pp. 681-686
    • Muscara, M.N.1    McKnight, W.2    Asfaha, S.3    Wallace, J.L.4
  • 31
    • 0028219709 scopus 로고
    • Antibody against single-stranded DNA detects both programmed cell death and drug-induced apoptosis
    • Naruse I, Keino H, and Kawarada Y. Antibody against single-stranded DNA detects both programmed cell death and drug-induced apoptosis. Histochemistry 101: 73-78, 1994.
    • (1994) Histochemistry , vol.101 , pp. 73-78
    • Naruse, I.1    Keino, H.2    Kawarada, Y.3
  • 32
    • 0028326795 scopus 로고
    • Mucosal tumor necrosis factor-α, interleukin-1β, and interleukin-8 production in patients with Helicobacter pylori infection
    • Noach LA, Bosma NB, Jansen J, Hoek FJ, van Deventer SJ, and Tytgat GN. Mucosal tumor necrosis factor-α, interleukin-1β, and interleukin-8 production in patients with Helicobacter pylori infection. Scand J Gastroenterol 29: 425-429, 1994.
    • (1994) Scand J Gastroenterol , vol.29 , pp. 425-429
    • Noach, L.A.1    Bosma, N.B.2    Jansen, J.3    Hoek, F.J.4    Van Deventer, S.J.5    Tytgat, G.N.6
  • 34
    • 0028332289 scopus 로고
    • Non-steroidal anti-inflammatory drugs (NSAID) cause gastrointestinal ulcers mainly in Helicobacter pylori carriers
    • Publig W, Wustinger C, and Zandl C. Non-steroidal anti-inflammatory drugs (NSAID) cause gastrointestinal ulcers mainly in Helicobacter pylori carriers. Wien Klin Wochenschr 106: 276-279, 1994.
    • (1994) Wien Klin Wochenschr , vol.106 , pp. 276-279
    • Publig, W.1    Wustinger, C.2    Zandl, C.3
  • 36
    • 0028846555 scopus 로고
    • Severe gastric mucosal damage induced by NSAIDs in healthy subjects is associated with Helicobacter pylori infection and high levels of serum pepsinogens
    • Santucci L, Fiorucci S, Patoia L, Di Matteo FM, Brunori PM, and Morelli A. Severe gastric mucosal damage induced by NSAIDs in healthy subjects is associated with Helicobacter pylori infection and high levels of serum pepsinogens. Dig Dis Sci 40: 2074-2080, 1995.
    • (1995) Dig Dis Sci , vol.40 , pp. 2074-2080
    • Santucci, L.1    Fiorucci, S.2    Patoia, L.3    Di Matteo, F.M.4    Brunori, P.M.5    Morelli, A.6
  • 37
    • 0032160712 scopus 로고    scopus 로고
    • Role of cyclooxygenase-2 in the healing of gastric ulcers in rats
    • Shigeta J, Takahashi S, and Okabe S. Role of cyclooxygenase-2 in the healing of gastric ulcers in rats. J Pharmacol Exp Ther 286: 1383-1390, 1998.
    • (1998) J Pharmacol Exp Ther , vol.286 , pp. 1383-1390
    • Shigeta, J.1    Takahashi, S.2    Okabe, S.3
  • 40
    • 0033680474 scopus 로고    scopus 로고
    • Role of cyclooxygenase-2 in Helicobacter pylori-induced gastritis in Mongolian gerbils
    • Takahashi S, Fujita T, and Yamamoto A. Role of cyclooxygenase-2 in Helicobacter pylori-induced gastritis in Mongolian gerbils. Am J Physiol Gastrointest Liver Physiol 279: G791-G798, 2000.
    • (2000) Am J Physiol Gastrointest Liver Physiol , vol.279
    • Takahashi, S.1    Fujita, T.2    Yamamoto, A.3
  • 43
    • 0028803728 scopus 로고
    • Alterations in cellular adhesion and apoptosis in epithelial cells overexpressing prostaglandin endoperoxide synthase 2
    • Tsujii M and DuBois RN. Alterations in cellular adhesion and apoptosis in epithelial cells overexpressing prostaglandin endoperoxide synthase 2. Cell 83: 493-501, 1995.
    • (1995) Cell , vol.83 , pp. 493-501
    • Tsujii, M.1    DuBois, R.N.2
  • 44
    • 0026656034 scopus 로고
    • Prostaglandins, NSAIDs, and cytoprotection
    • Wallace JL. Prostaglandins, NSAIDs, and cytoprotection. Gastroenterol Clin North Am 21: 631-641, 1992.
    • (1992) Gastroenterol Clin North Am , vol.21 , pp. 631-641
    • Wallace, J.L.1
  • 45
    • 0033050264 scopus 로고    scopus 로고
    • Limited anti-inflammatory efficacy of cyclo-oxygenase-2 inhibition in carrageenan-airpouch inflammation
    • Wallace JL, Chapman K, and McKnight W. Limited anti-inflammatory efficacy of cyclo-oxygenase-2 inhibition in carrageenan-airpouch inflammation. Br J Pharmacol 126: 1200-1204, 1999.
    • (1999) Br J Pharmacol , vol.126 , pp. 1200-1204
    • Wallace, J.L.1    Chapman, K.2    McKnight, W.3
  • 46
    • 0033851568 scopus 로고    scopus 로고
    • NSAID-induced gastric damage in rats: Requirement for inhibition of both cyclooxygenase 1 and 2
    • Wallace JL, McKnight W, Reuter BK, and Vergnolle N. NSAID-induced gastric damage in rats: requirement for inhibition of both cyclooxygenase 1 and 2. Gastroenterology 119: 706-714, 2000.
    • (2000) Gastroenterology , vol.119 , pp. 706-714
    • Wallace, J.L.1    McKnight, W.2    Reuter, B.K.3    Vergnolle, N.4
  • 47
    • 0018904225 scopus 로고
    • Selective inhibition of prostaglandin production in inflammatory exudates and gastric mucosa
    • Whittle BJ, Higgs GA, Eakins KE, Moncada S, and Vane JR. Selective inhibition of prostaglandin production in inflammatory exudates and gastric mucosa. Nature 284: 271-273, 1980.
    • (1980) Nature , vol.284 , pp. 271-273
    • Whittle, B.J.1    Higgs, G.A.2    Eakins, K.E.3    Moncada, S.4    Vane, J.R.5
  • 48
    • 0036113788 scopus 로고    scopus 로고
    • Helicobacter pylori infection potentiates aspirin induced gastric mucosal injury in Mongolian gerbils
    • Yoshida N, Sugimoto N, Hirayama F, Nakamura Y, Ichikawa H, Naito Y, and Yoshikawa T. Helicobacter pylori infection potentiates aspirin induced gastric mucosal injury in Mongolian gerbils. Gut 50: 594-598, 2002.
    • (2002) Gut , vol.50 , pp. 594-598
    • Yoshida, N.1    Sugimoto, N.2    Hirayama, F.3    Nakamura, Y.4    Ichikawa, H.5    Naito, Y.6    Yoshikawa, T.7


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.