메뉴 건너뛰기




Volumn 93, Issue 11, 2004, Pages 2851-2862

Effects of different N-trimethyl chitosans on in vitro/in vivo ofloxacin transcorneal permeation

Author keywords

Absorption enhancer; Cell culture; in vitro models; in vitro in vivo correlations; Mucosal delivery; N trimethyl chitosan; Ocular drug delivery; Ofloxacin; Permeability; Polymeric biomaterials

Indexed keywords

CHITOSAN; DIETHYLAMINOETHYLDEXTRAN; OFLOXACIN;

EID: 8644259904     PISSN: 00223549     EISSN: None     Source Type: Journal    
DOI: 10.1002/jps.20197     Document Type: Article
Times cited : (83)

References (31)
  • 1
    • 0028071051 scopus 로고
    • Effect of chitosan on the permeability of monolayers of intestinal epithelial cells (Caco-2)
    • Artursson P, Lindmark T, Davis SS, Illum L. 1994. Effect of chitosan on the permeability of monolayers of intestinal epithelial cells (Caco-2). Pharm Res 11:1358-1361.
    • (1994) Pharm Res , vol.11 , pp. 1358-1361
    • Artursson, P.1    Lindmark, T.2    Davis, S.S.3    Illum, L.4
  • 2
    • 0031018133 scopus 로고    scopus 로고
    • Mucoadhesive polymers in peroral peptide drug delivery. IV. Polycarbophil and chitosan are potent enhancers of peptide transport across intestinal mucosae in vitro
    • Lueßen HL, Rentel CO, Kotzé AF, Lehr CM, de Boer AG, Verhoef JC, Junginger HE. 1997. Mucoadhesive polymers in peroral peptide drug delivery. IV. Polycarbophil and chitosan are potent enhancers of peptide transport across intestinal mucosae in vitro. J Controlled Release 45:15-23.
    • (1997) J Controlled Release , vol.45 , pp. 15-23
    • Lueßen, H.L.1    Rentel, C.O.2    Kotzé, A.F.3    Lehr, C.M.4    De Boer, A.G.5    Verhoef, J.C.6    Junginger, H.E.7
  • 3
    • 0030453145 scopus 로고    scopus 로고
    • Mucoadhesive polymers in peroral peptide drug delivery. VI. Carbomer and chitosan improve the intestinal absorption of the peptide drug buserelin in vivo
    • Lueßen HL, de Leeuw BJ, Langemeyer MW, de Boer AB, Verhoef JC, Junginger HE. 1996. Mucoadhesive polymers in peroral peptide drug delivery. VI. Carbomer and chitosan improve the intestinal absorption of the peptide drug buserelin in vivo. Pharm Res 13:1668-1672.
    • (1996) Pharm Res , vol.13 , pp. 1668-1672
    • Lueßen, H.L.1    De Leeuw, B.J.2    Langemeyer, M.W.3    De Boer, A.B.4    Verhoef, J.C.5    Junginger, H.E.6
  • 4
    • 0343150936 scopus 로고    scopus 로고
    • The potential of mucoadhesive polymers in enhancing intestinal peptide drug absorption. III: Effects of chitosan-glutamate and carbomer on epithelial tight junctions in vitro
    • Borchard G, Lueßen HL, de Boer AG, Verhoef JC, Lehr CM, Junginger HE. 1996. The potential of mucoadhesive polymers in enhancing intestinal peptide drug absorption. III: Effects of chitosan-glutamate and carbomer on epithelial tight junctions in vitro. J Controlled Release 39:131-138.
    • (1996) J Controlled Release , vol.39 , pp. 131-138
    • Borchard, G.1    Lueßen, H.L.2    De Boer, A.G.3    Verhoef, J.C.4    Lehr, C.M.5    Junginger, H.E.6
  • 5
    • 0028124642 scopus 로고
    • Chitosan as a novel nasal delivery system for peptide drugs
    • Illum L, Farraj NF, Davis SS. 1994. Chitosan as a novel nasal delivery system for peptide drugs. Pharm Res 11:1186-1189.
    • (1994) Pharm Res , vol.11 , pp. 1186-1189
    • Illum, L.1    Farraj, N.F.2    Davis, S.S.3
  • 6
    • 1542328829 scopus 로고    scopus 로고
    • Effect of chitosan and of N-carboxymethylchitosan on intraocular penetration of topically sapplied ofloxacin
    • Di Colo G, Zambito Y, Burgalassi S, Nardini I, Saettone MF. 2004. Effect of chitosan and of N-carboxymethylchitosan on intraocular penetration of topically sapplied ofloxacin. Int J Pharm 273: 37-44.
    • (2004) Int J Pharm , vol.273 , pp. 37-44
    • Di Colo, G.1    Zambito, Y.2    Burgalassi, S.3    Nardini, I.4    Saettone, M.F.5
  • 8
    • 0034879035 scopus 로고    scopus 로고
    • Chitosan: Some pharmaceutical and biological aspects - An update
    • Singla AK, Chawla M. 2001. Chitosan: Some pharmaceutical and biological aspects - An update. J Pharm Pharmacol 53:1047-1067.
    • (2001) J Pharm Pharmacol , vol.53 , pp. 1047-1067
    • Singla, A.K.1    Chawla, M.2
  • 9
    • 0030839517 scopus 로고    scopus 로고
    • N-trimethyl chitosan chloride as a potential absorption enhancer across mucosal surfaces: In vitro evaluation in intestinal epithelial cells (Caco-2)
    • Kotzé AF, Lueßen HL, De Leeuw BJ, De Boer AG, Verhoef JC, Junginger HE. 1997. N-trimethyl chitosan chloride as a potential absorption enhancer across mucosal surfaces: In vitro evaluation in intestinal epithelial cells (Caco-2). Pharm Res 14: 1197-1202.
    • (1997) Pharm Res , vol.14 , pp. 1197-1202
    • Kotzé, A.F.1    Lueßen, H.L.2    De Leeuw, B.J.3    De Boer, A.G.4    Verhoef, J.C.5    Junginger, H.E.6
  • 10
    • 0345055299 scopus 로고    scopus 로고
    • Comparison of the effect of different chitosan salts and N-trimethyl chitosan chloride on the permeability of intestinal epithelial cells (Caco-2)
    • Kotzé AF, Lueßen HL, De Leeuw BJ, De Boer AG, Verhoef JC, Junginger HE. 1998. Comparison of the effect of different chitosan salts and N-trimethyl chitosan chloride on the permeability of intestinal epithelial cells (Caco-2). J Controlled Release 51:35-46.
    • (1998) J Controlled Release , vol.51 , pp. 35-46
    • Kotzé, A.F.1    Lueßen, H.L.2    De Leeuw, B.J.3    De Boer, A.G.4    Verhoef, J.C.5    Junginger, H.E.6
  • 11
    • 0034049537 scopus 로고    scopus 로고
    • N-trimethyl chitosan chloride (TMC) improves the intestinal permeation of the peptide drug buserelin in vitro (Caco-2 cells) and in vivo (rats)
    • Thanou M, Florea BI, Langemeyer MWE, Verhoef JC, Junginger HE. 2000. N-trimethyl chitosan chloride (TMC) improves the intestinal permeation of the peptide drug buserelin in vitro (Caco-2 cells) and in vivo (rats). Pharm Res 17:27-31.
    • (2000) Pharm Res , vol.17 , pp. 27-31
    • Thanou, M.1    Florea, B.I.2    Langemeyer, M.W.E.3    Verhoef, J.C.4    Junginger, H.E.5
  • 12
    • 0030787377 scopus 로고    scopus 로고
    • Chitosan as absorption enhancer for poorly absorbable drugs 2: Mechanism of absorption enhancement
    • Schipper GM, Olsson S, Hoogstraate JA, De Boer AG, Varum KM, Artusson P. 1997. Chitosan as absorption enhancer for poorly absorbable drugs 2: Mechanism of absorption enhancement. Pharm Res 14:923-929.
    • (1997) Pharm Res , vol.14 , pp. 923-929
    • Schipper, G.M.1    Olsson, S.2    Hoogstraate, J.A.3    De Boer, A.G.4    Varum, K.M.5    Artusson, P.6
  • 13
    • 0033039070 scopus 로고    scopus 로고
    • Effect of the degree of quaternization of N-trimethyl chitosan chloride on the permeability of intestinal epithelial cells (Caco-2)
    • Kotzé AF, Thanou M, Lueßen HL, De Boer AG, Verhoef JC, Junginger HE. 1999. Effect of the degree of quaternization of N-trimethyl chitosan chloride on the permeability of intestinal epithelial cells (Caco-2). Eur J Pharm Biopharm 47:269-274.
    • (1999) Eur J Pharm Biopharm , vol.47 , pp. 269-274
    • Kotzé, A.F.1    Thanou, M.2    Lueßen, H.L.3    De Boer, A.G.4    Verhoef, J.C.5    Junginger, H.E.6
  • 14
    • 0037219709 scopus 로고    scopus 로고
    • N-trimethyl chitosan chloride: Optimum degree of quaternization for drug absorption enhancement across epithelial cells
    • Hamman JH, Schultz CM, Kotzé AF. 2003. N-trimethyl chitosan chloride: Optimum degree of quaternization for drug absorption enhancement across epithelial cells. Drug Dev Ind Pharm 29: 161-172.
    • (2003) Drug Dev Ind Pharm , vol.29 , pp. 161-172
    • Hamman, J.H.1    Schultz, C.M.2    Kotzé, A.F.3
  • 16
    • 0034957378 scopus 로고    scopus 로고
    • Effect of the type of base and number of reaction steps on the degree of quaternization and molecular weight of N-trimethyl chitosan chloride
    • Hamman JH, Kotzé AF. 2001. Effect of the type of base and number of reaction steps on the degree of quaternization and molecular weight of N-trimethyl chitosan chloride. Drug Dev Ind Pharm 27:373-380.
    • (2001) Drug Dev Ind Pharm , vol.27 , pp. 373-380
    • Hamman, J.H.1    Kotzé, A.F.2
  • 17
    • 0031043666 scopus 로고    scopus 로고
    • Studies of DEAE-dextran-mediated gene transfer
    • Yang YW, Yang JC. 1997. Studies of DEAE-dextran-mediated gene transfer. Biotechnol Appl Biochem 25:47-51.
    • (1997) Biotechnol Appl Biochem , vol.25 , pp. 47-51
    • Yang, Y.W.1    Yang, J.C.2
  • 18
    • 0032004238 scopus 로고    scopus 로고
    • A novel method for DEAE-dextran mediated transfection of adherent primary cultured human macrophages
    • Mack KD, Wei R, Elbagarri A, Abbey N, McGrath MS. 1998. A novel method for DEAE-dextran mediated transfection of adherent primary cultured human macrophages. J Immunol Methods 211: 79-86.
    • (1998) J Immunol Methods , vol.211 , pp. 79-86
    • Mack, K.D.1    Wei, R.2    Elbagarri, A.3    Abbey, N.4    McGrath, M.S.5
  • 19
    • 0037222237 scopus 로고    scopus 로고
    • Enhancement of adenovirus-mediated gene transfer to the airways by DEAE dextran and sodium caprate in vivo
    • Gregory LG, Harbottle RP, Lawrence L, Knapton HJ, Themis M, Coutelle C. 2003. Enhancement of adenovirus-mediated gene transfer to the airways by DEAE dextran and sodium caprate in vivo. Mol Ther 7:19-26.
    • (2003) Mol Ther , vol.7 , pp. 19-26
    • Gregory, L.G.1    Harbottle, R.P.2    Lawrence, L.3    Knapton, H.J.4    Themis, M.5    Coutelle, C.6
  • 21
    • 0032885393 scopus 로고    scopus 로고
    • Swelling properties and mechanical characterisation of a semi-interpenetrating chitosan/polyethylene oxide network. Comparison with a chitosan reference gel
    • Khalid MN, Ho L, Agnely F, Grossiord JL, Couarraze G. 1999. Swelling properties and mechanical characterisation of a semi-interpenetrating chitosan/polyethylene oxide network. Comparison with a chitosan reference gel. STP Pharma Sci 9: 359-364.
    • (1999) STP Pharma Sci , vol.9 , pp. 359-364
    • Khalid, M.N.1    Ho, L.2    Agnely, F.3    Grossiord, J.L.4    Couarraze, G.5
  • 22
    • 0037032435 scopus 로고    scopus 로고
    • Effect of chitosan on in vitro release and ocular delivery of ofloxacin from erodible inserts based on poly(ethylene oxide)
    • Di Colo G, Zambito Y, Burgalassi S, Serafini A, Saettone MF. 2002. Effect of chitosan on in vitro release and ocular delivery of ofloxacin from erodible inserts based on poly(ethylene oxide). Int J Pharm 248:115-122.
    • (2002) Int J Pharm , vol.248 , pp. 115-122
    • Di Colo, G.1    Zambito, Y.2    Burgalassi, S.3    Serafini, A.4    Saettone, M.F.5
  • 23
    • 0035978495 scopus 로고    scopus 로고
    • Cytotoxicity of potential ocular permeation enhancers evaluated on rabbit and human corneal epithelial cell lines
    • Burgalassi S, Chetoni P, Monti D, Saettone MF. 2001. Cytotoxicity of potential ocular permeation enhancers evaluated on rabbit and human corneal epithelial cell lines. Toxicol Lett 122:1-8.
    • (2001) Toxicol Lett , vol.122 , pp. 1-8
    • Burgalassi, S.1    Chetoni, P.2    Monti, D.3    Saettone, M.F.4
  • 25
    • 0036059079 scopus 로고    scopus 로고
    • A study of release mechanism of different ophthalmic drugs from erodible ocular inserts based on poly(ethylene oxide)
    • Di Colo G, Zambito Y. 2002. A study of release mechanism of different ophthalmic drugs from erodible ocular inserts based on poly(ethylene oxide). Eur J Pharm Biopharm 54:193-199.
    • (2002) Eur J Pharm Biopharm , vol.54 , pp. 193-199
    • Di Colo, G.1    Zambito, Y.2
  • 26
    • 0016814399 scopus 로고
    • Evaluation of a dynamic permeation technique for studying drug-macromolecule interactions
    • Bottari F, Di Colo G, Nannipieri E, Saettone MF, Serafini MF. 1975. Evaluation of a dynamic permeation technique for studying drug-macromolecule interactions. J Pharm Sci 64:946-949.
    • (1975) J Pharm Sci , vol.64 , pp. 946-949
    • Bottari, F.1    Di Colo, G.2    Nannipieri, E.3    Saettone, M.F.4    Serafini, M.F.5
  • 28
    • 12244256118 scopus 로고    scopus 로고
    • Evaluation of the mucoadhesive properties of N-trimethyl chitosan chloride
    • Snyman D, Hamman JH, Kotze AF. 2003. Evaluation of the mucoadhesive properties of N-trimethyl chitosan chloride. Drug Dev Ind Pharm 29:61-69.
    • (2003) Drug Dev Ind Pharm , vol.29 , pp. 61-69
    • Snyman, D.1    Hamman, J.H.2    Kotze, A.F.3
  • 29
    • 0036832895 scopus 로고    scopus 로고
    • The relationship between the absolute molecular weight and the degree of quaternisation of N-trimethyl chitosan chloride
    • Snyman D, Hamman JH, Kotze JS, Rollings JE, Kotzé AF. 2002. The relationship between the absolute molecular weight and the degree of quaternisation of N-trimethyl chitosan chloride. Carbohyd Polym 50:145-150.
    • (2002) Carbohyd Polym , vol.50 , pp. 145-150
    • Snyman, D.1    Hamman, J.H.2    Kotze, J.S.3    Rollings, J.E.4    Kotzé, A.F.5
  • 30
    • 0025201777 scopus 로고
    • Aqueous solubilities of variously substituted quinolone antimicrobials
    • Ross DL, Riley CM. 1990. Aqueous solubilities of variously substituted quinolone antimicrobials. Int J Pharm 63:237-250.
    • (1990) Int J Pharm , vol.63 , pp. 237-250
    • Ross, D.L.1    Riley, C.M.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.