-
1
-
-
0342618532
-
Presence of fetal DNA in maternal plasma and serum
-
Lo, Y.D., Corbetta, N., Chamberlain, P.F., Rai, V., Sargent, I.L., Redman, C.W., Wainscoat, J.S. Presence of fetal DNA in maternal plasma and serum. Lancet 1997, 350, 485-487.
-
(1997)
Lancet
, vol.350
, pp. 485-487
-
-
Lo, Y.D.1
Corbetta, N.2
Chamberlain, P.F.3
Rai, V.4
Sargent, I.L.5
Redman, C.W.6
Wainscoat, J.S.7
-
2
-
-
84957852098
-
The nucleic acids in blood plasma in humans
-
Mandel, P., Metais, P. The nucleic acids in blood plasma in humans. C. R. Seances Soc. Biol. Fil. 1948, 142, 241-243.
-
(1948)
C. R. Seances Soc. Biol. Fil
, vol.142
, pp. 241-243
-
-
Mandel, P.1
Metais, P.2
-
3
-
-
84859153002
-
Noninvasive prenatal diagnosis empowered by high-throughput sequencing
-
Chiu, R.W., Lo, Y.M. Noninvasive prenatal diagnosis empowered by high-throughput sequencing. Prenat. Diagn. 2012, 32, 401-406.
-
(2012)
Prenat. Diagn
, vol.32
, pp. 401-406
-
-
Chiu, R.W.1
Lo, Y.M.2
-
4
-
-
84937459187
-
Noninvasive Prenatal Testing and Incidental Detection of Occult Maternal Malignancies
-
Bianchi, D.W., Chudova, D., Sehnert, A.J., Bhatt, S., Murray, K., Prosen, T.L., Garber, J.E., Wilkins-Haug, L., Vora, N.L., Warsof, S., et al. Noninvasive Prenatal Testing and Incidental Detection of Occult Maternal Malignancies. JAMA 2015, 314, 162-169.
-
(2015)
JAMA
, vol.314
, pp. 162-169
-
-
Bianchi, D.W.1
Chudova, D.2
Sehnert, A.J.3
Bhatt, S.4
Murray, K.5
Prosen, T.L.6
Garber, J.E.7
Wilkins-Haug, L.8
Vora, N.L.9
Warsof, S.10
-
5
-
-
0017360626
-
Free DNA in the serum of cancer patients and the effect of therapy
-
Leon, S.A., Shapiro, B., Sklaroff, D.M., Yaros, M.J. Free DNA in the serum of cancer patients and the effect of therapy. Cancer Res. 1977, 37, 646-650.
-
(1977)
Cancer Res
, vol.37
, pp. 646-650
-
-
Leon, S.A.1
Shapiro, B.2
Sklaroff, D.M.3
Yaros, M.J.4
-
6
-
-
0027232296
-
Detection of ras gene mutations in pancreatic juice and peripheral blood of patients with pancreatic adenocarcinoma
-
Tada, M., Omata, M., Kawai, S., Saisho, H., Ohto, M., Saiki, R.K., Sninsky, J.J. Detection of ras gene mutations in pancreatic juice and peripheral blood of patients with pancreatic adenocarcinoma. Cancer Res. 1993, 53, 2472-2474.
-
(1993)
Cancer Res
, vol.53
, pp. 2472-2474
-
-
Tada, M.1
Omata, M.2
Kawai, S.3
Saisho, H.4
Ohto, M.5
Saiki, R.K.6
Sninsky, J.J.7
-
7
-
-
51349141191
-
Circulating mutant DNA to assess tumor dynamics
-
Diehl, F., Schmidt, K., Choti, M.A., Romans, K., Goodman, S., Li, M., Thornton, K., Agrawal, N., Sokoll, L., Szabo, S.A., et al. Circulating mutant DNA to assess tumor dynamics. Nat. Med. 2008, 14, 985-990.
-
(2008)
Nat. Med
, vol.14
, pp. 985-990
-
-
Diehl, F.1
Schmidt, K.2
Choti, M.A.3
Romans, K.4
Goodman, S.5
Li, M.6
Thornton, K.7
Agrawal, N.8
Sokoll, L.9
Szabo, S.A.10
-
8
-
-
84898542288
-
Liquid biopsies: Genotyping circulating tumor DNA
-
Diaz, L.A., Jr., Bardelli, A. Liquid biopsies: Genotyping circulating tumor DNA. J. Clin. Oncol. 2014, 32, 579-586.
-
(2014)
J. Clin. Oncol
, vol.32
, pp. 579-586
-
-
Diaz, L.A.1
Bardelli, A.2
-
9
-
-
84955452903
-
SNPase-ARMS qPCR: Ultrasensitive Mutation-Based Detection of Cell-Free Tumor DNA in Melanoma Patients
-
Stadler, J., Eder, J., Pratscher, B., Brandt, S., Schneller, D., Müllegger, R., Vogl, C., Trautinger, F., Brem, G., Burgstaller, J.P. SNPase-ARMS qPCR: Ultrasensitive Mutation-Based Detection of Cell-Free Tumor DNA in Melanoma Patients. PLoS ONE 2015, 10, e0142273.
-
(2015)
Plos ONE
, vol.10
-
-
Stadler, J.1
Eder, J.2
Pratscher, B.3
Brandt, S.4
Schneller, D.5
Müllegger, R.6
Vogl, C.7
Trautinger, F.8
Brem, G.9
Burgstaller, J.P.10
-
10
-
-
84949009842
-
Analytical and Clinical Validation of a Digital Sequencing Panel for Quantitative, Highly Accurate Evaluation of Cell-Free Circulating Tumor DNA
-
Lanman, R.B., Mortimer, S.A., Zill, O.A., Sebisanovic, D., Lopez, R., Blau, S., Collisson, E.A., Divers, S.G., Hoon, D.S., Kopetz, E.S., et al. Analytical and Clinical Validation of a Digital Sequencing Panel for Quantitative, Highly Accurate Evaluation of Cell-Free Circulating Tumor DNA. PLoS ONE 2015, 10, e0140712.
-
(2015)
Plos ONE
, vol.10
-
-
Lanman, R.B.1
Mortimer, S.A.2
Zill, O.A.3
Sebisanovic, D.4
Lopez, R.5
Blau, S.6
Collisson, E.A.7
Divers, S.G.8
Hoon, D.S.9
Kopetz, E.S.10
-
11
-
-
84966365311
-
Integrated digital error suppression for improved detection of circulating tumor DNA
-
Newman, A.M., Lovejoy, A.F., Klass, D.M., Kurtz, D.M., Chabon, J.J., Scherer, F., Stehr, H., Liu, C.L., Bratman, S.V., Say, C., et al. Integrated digital error suppression for improved detection of circulating tumor DNA. Nat. Biotechnol. 2016, 34, 547-555.
-
(2016)
Nat. Biotechnol
, vol.34
, pp. 547-555
-
-
Newman, A.M.1
Lovejoy, A.F.2
Klass, D.M.3
Kurtz, D.M.4
Chabon, J.J.5
Scherer, F.6
Stehr, H.7
Liu, C.L.8
Bratman, S.V.9
Say, C.10
-
12
-
-
0035866393
-
Fragments in the blood plasma of cancer patients: Quantitations and evidence for their origin from apoptotic and necrotic cells
-
Jahr, S., Hentze, H., Englisch, S., Hardt, D., Fackelmayer, F.O., Hesch, R.D., Knippers, R. DNA fragments in the blood plasma of cancer patients: Quantitations and evidence for their origin from apoptotic and necrotic cells. Cancer Res. 2001, 61, 1659-1665.
-
(2001)
Cancer Res
, vol.61
, pp. 1659-1665
-
-
Jahr, S.1
Hentze, H.2
Englisch, S.3
Hardt, D.4
Fackelmayer, F.O.5
Hesch, R.D.6
Knippers, R.7
-
13
-
-
84904061727
-
Blood-based analyses of cancer: Circulating tumor cells and circulating tumor DNA
-
Haber, D.A., Velculescu, V.E. Blood-based analyses of cancer: Circulating tumor cells and circulating tumor DNA. Cancer Discov. 2014, 4, 650-661.
-
(2014)
Cancer Discov
, vol.4
, pp. 650-661
-
-
Haber, D.A.1
Velculescu, V.E.2
-
14
-
-
77956467360
-
Cell-free DNA in the blood as a solid tumor biomarker—A critical appraisal of the literature
-
Jung, K., Fleischhacker, M., Rabien, A. Cell-free DNA in the blood as a solid tumor biomarker—A critical appraisal of the literature. Clin. Chim. Acta 2010, 411, 1611-1624.
-
(2010)
Clin. Chim. Acta
, vol.411
, pp. 1611-1624
-
-
Jung, K.1
Fleischhacker, M.2
Rabien, A.3
-
15
-
-
28044468634
-
Detection and quantification of mutations in the plasma of patients with colorectal tumors
-
Diehl, F., Li, M., Dressman, D., He, Y., Shen, D., Szabo, S., Diaz, L.A., Goodman, S.N., David, K.A., Juhl, H., et al. Detection and quantification of mutations in the plasma of patients with colorectal tumors. Proc. Natl. Acad. Sci. USA 2005, 102, 16368-16373.
-
(2005)
Proc. Natl. Acad. Sci. USA
, vol.102
, pp. 16368-16373
-
-
Diehl, F.1
Li, M.2
Dressman, D.3
He, Y.4
Shen, D.5
Szabo, S.6
Diaz, L.A.7
Goodman, S.N.8
David, K.A.9
Juhl, H.10
-
16
-
-
0034750559
-
About the possible origin and mechanism of circulating DNA apoptosis and active DNA release
-
Stroun, M., Lyautey, J., Lederrey, C., Olson-Sand, A., Anker, P. About the possible origin and mechanism of circulating DNA apoptosis and active DNA release. Clin. Chim. Acta 2001, 313, 139-142.
-
(2001)
Clin. Chim. Acta
, vol.313
, pp. 139-142
-
-
Stroun, M.1
Lyautey, J.2
Lederrey, C.3
Olson-Sand, A.4
Anker, P.5
-
17
-
-
84925338452
-
Lengthening and shortening of plasma DNA in hepatocellular carcinoma patients
-
Jiang, P., Chan, C.W., Chan, K.A., Cheng, S.H., Wong, J., Wong, V.W., Wong, G.L., Chan, S.L., Mok, T.S., Chan, H.L., et al. Lengthening and shortening of plasma DNA in hepatocellular carcinoma patients. Proc. Natl. Acad. Sci. USA 2015, 112, E1317-E1325.
-
(2015)
Proc. Natl. Acad. Sci. USA
, vol.112
, pp. E1317-E1325
-
-
Jiang, P.1
Chan, C.W.2
Chan, K.A.3
Cheng, S.H.4
Wong, J.5
Wong, V.W.6
Wong, G.L.7
Chan, S.L.8
Mok, T.S.9
Chan, H.L.10
-
18
-
-
80052436485
-
High fragmentation characterizes tumour-derived circulating DNA
-
Mouliere, F., Robert, B., Peyrotte, E.A., Del Rio, M., Ychou, M., Molina, F., Gongora, C., Thierry, A.R. High fragmentation characterizes tumour-derived circulating DNA. PLoS ONE 2011, 6, e23418.
-
(2011)
Plos ONE
, vol.6
-
-
Mouliere, F.1
Robert, B.2
Peyrotte, E.A.3
Del Rio, M.4
Ychou, M.5
Molina, F.6
Gongora, C.7
Thierry, A.R.8
-
19
-
-
84903692972
-
Plasma DNA integrity as a biomarker for primary and metastatic breast cancer and potential marker for early diagnosis
-
Madhavan, D., Wallwiener, M., Bents, K., Zucknick, M., Nees, J., Schott, S., Cuk, K., Riethdorf, S., Trumpp, A., Pantel, K., et al. Plasma DNA integrity as a biomarker for primary and metastatic breast cancer and potential marker for early diagnosis. Breast Cancer Res. Treat. 2014, 146, 163-174.
-
(2014)
Breast Cancer Res. Treat
, vol.146
, pp. 163-174
-
-
Madhavan, D.1
Wallwiener, M.2
Bents, K.3
Zucknick, M.4
Nees, J.5
Schott, S.6
Cuk, K.7
Riethdorf, S.8
Trumpp, A.9
Pantel, K.10
-
20
-
-
84918509823
-
Increased DNA integrity in colorectal cancer
-
Leszinski, G., Lehner, J., Gezer, U. Increased DNA integrity in colorectal cancer. In Vivo 2014, 28, 299-303.
-
(2014)
In Vivo
, vol.28
, pp. 299-303
-
-
Leszinski, G.1
Lehner, J.2
Gezer, U.3
-
21
-
-
84896371874
-
Detection of circulating tumor DNA in early-and late-stage human malignancies
-
224ra24
-
Bettegowda, C., Sausen, M., Leary, R.J., Kinde, I., Wang, Y., Agrawal, N., Bartlett, B.R., Wang, H., Luber, B., Alani, R.M., et al. Detection of circulating tumor DNA in early-and late-stage human malignancies. Sci. Transl. Med. 2014, 6, 224ra24.
-
(2014)
Sci. Transl. Med
, vol.6
-
-
Bettegowda, C.1
Sausen, M.2
Leary, R.J.3
Kinde, I.4
Wang, Y.5
Agrawal, N.6
Bartlett, B.R.7
Wang, H.8
Luber, B.9
Alani, R.M.10
-
22
-
-
78649907173
-
Distinctive DNA methylation patterns of cell-free plasma DNA in women with malignant ovarian tumors
-
Liggett, T.E., Melnikov, A., Yi, Q., Replogle, C., Hu, W., Rotmensch, J., Kamat, A., Sood, A.K., Levenson, V. Distinctive DNA methylation patterns of cell-free plasma DNA in women with malignant ovarian tumors. Gynecol. Oncol. 2011, 120, 113-120.
-
(2011)
Gynecol. Oncol
, vol.120
, pp. 113-120
-
-
Liggett, T.E.1
Melnikov, A.2
Yi, Q.3
Replogle, C.4
Hu, W.5
Rotmensch, J.6
Kamat, A.7
Sood, A.K.8
Levenson, V.9
-
23
-
-
84870326702
-
Genome-scale discovery of DNA-methylation biomarkers for blood-based detection of colorectal cancer
-
Lange, C.P., Campan, M., Hinoue, T., Schmitz, R.F., van der Meulen-de, A.E., Slingerland, H., Kok, P.J., van Dijk, C.M., Weisenberger, D.J., Shen, H., et al. Genome-scale discovery of DNA-methylation biomarkers for blood-based detection of colorectal cancer. PLoS ONE 2012, 7, e50266.
-
(2012)
Plos ONE
, vol.7
-
-
Lange, C.P.1
Campan, M.2
Hinoue, T.3
Schmitz, R.F.4
Van Der Meulen-De, A.E.5
Slingerland, H.6
Kok, P.J.7
Van Dijk, C.M.8
Weisenberger, D.J.9
Shen, H.10
-
24
-
-
84908548256
-
Methylated Glutathione S-transferase 1 (MGSTP1) is a potential plasma free DNA epigenetic marker of prognosis and response to chemotherapy in castrate-resistant prostate cancer
-
Mahon, K.L., Qu, W., Devaney, J., Paul, C., Castillo, L., Wykes, R.J., Chatfield, M.D., Boyer, M.J., Stockler, M.R., Marx, G., et al. Methylated Glutathione S-transferase 1 (mGSTP1) is a potential plasma free DNA epigenetic marker of prognosis and response to chemotherapy in castrate-resistant prostate cancer. Br. J. Cancer 2014, 1119, 1802-1809.
-
(2014)
Br. J. Cancer
, vol.1119
, pp. 1802-1809
-
-
Mahon, K.L.1
Qu, W.2
Devaney, J.3
Paul, C.4
Castillo, L.5
Wykes, R.J.6
Chatfield, M.D.7
Boyer, M.J.8
Stockler, M.R.9
Marx, G.10
-
25
-
-
84960803239
-
Robust Detection of DNA Hypermethylation of ZNF154 as a Pan-Cancer Locus with in Silico Modeling for Blood-Based Diagnostic Development
-
Margolin, G., Petrykowska, H.M., Jameel, N., Bell, D.W., Young, A.C., Elnitski, L. Robust Detection of DNA Hypermethylation of ZNF154 as a Pan-Cancer Locus with in Silico Modeling for Blood-Based Diagnostic Development. J. Mol. Diagn. 2016, 18, 283-298.
-
(2016)
J. Mol. Diagn
, vol.18
, pp. 283-298
-
-
Margolin, G.1
Petrykowska, H.M.2
Jameel, N.3
Bell, D.W.4
Young, A.C.5
Elnitski, L.6
-
26
-
-
0015043748
-
Mutation and cancer: Statistical study of retinoblastoma
-
Knudson, A.G., Jr. Mutation and cancer: Statistical study of retinoblastoma. Proc. Natl. Acad. Sci. USA 1971, 68, 820-823.
-
(1971)
Proc. Natl. Acad. Sci. USA
, vol.68
, pp. 820-823
-
-
Knudson, A.G.1
-
27
-
-
84978685765
-
Overview of Targeted Therapies for Cancer
-
on 23 July
-
Abramson, R. Overview of Targeted Therapies for Cancer. My Cancer Genome, 2016. Available online: https://www.mycancergenome.org/content/molecular-medicine/overview-of-targeted-therapies-forcancer/ (accessed on 23 July 2016).
-
(2016)
My Cancer Genome
-
-
Abramson, R.1
-
28
-
-
84943663755
-
The translational potential of circulating tumour DNA in oncology
-
Patel, K.M., Tsui, D.W. The translational potential of circulating tumour DNA in oncology. Clin. Biochem. 2015, 48, 957-961.
-
(2015)
Clin. Biochem
, vol.48
, pp. 957-961
-
-
Patel, K.M.1
Tsui, D.W.2
-
29
-
-
84863393080
-
Intratumor heterogeneity and branched evolution revealed by multiregion sequencing
-
Gerlinger, M., Rowan, A.J., Horswell, S., Larkin, J., Endesfelder, D., Gronroos, E., Martinez, P., Matthews, N., Stewart, A., Tarpey, P., et al. Intratumor heterogeneity and branched evolution revealed by multiregion sequencing. N. Engl. J. Med. 2012, 366, 883-892.
-
(2012)
N. Engl. J. Med
, vol.366
, pp. 883-892
-
-
Gerlinger, M.1
Rowan, A.J.2
Horswell, S.3
Larkin, J.4
Endesfelder, D.5
Gronroos, E.6
Martinez, P.7
Matthews, N.8
Stewart, A.9
Tarpey, P.10
-
30
-
-
84868682387
-
Multi-purpose utility of circulating plasma DNA testing in patients with advanced cancers
-
Perkins, G., Yap, T.A., Pope, L., Cassidy, A.M., Dukes, J.P., Riisnaes, R., Massard, C., Cassier, P.A., Miranda, S., Clark, J., et al. Multi-purpose utility of circulating plasma DNA testing in patients with advanced cancers. PLoS ONE 2012, 7, e47020.
-
(2012)
Plos ONE
, vol.7
-
-
Perkins, G.1
Yap, T.A.2
Pope, L.3
Cassidy, A.M.4
Dukes, J.P.5
Riisnaes, R.6
Massard, C.7
Cassier, P.A.8
Miranda, S.9
Clark, J.10
-
31
-
-
84936132730
-
Noninvasive diagnosis of actionable mutations by deep sequencing of circulating free DNA in lung cancer from never-smokers: A proof-of-concept study from BioCAST/IFCT-1002
-
Couraud, S., Vaca-Paniagua, F., Villar, S., Oliver, J., Schuster, T., Blanché, H., Girard, N., Trédaniel, J., Guilleminault, L., Gervais, R., et al. Noninvasive diagnosis of actionable mutations by deep sequencing of circulating free DNA in lung cancer from never-smokers: A proof-of-concept study from BioCAST/IFCT-1002. Clin Cancer Res. 2014, 20, 4613-4624.
-
(2014)
Clin Cancer Res
, vol.20
, pp. 4613-4624
-
-
Couraud, S.1
Vaca-Paniagua, F.2
Villar, S.3
Oliver, J.4
Schuster, T.5
Blanché, H.6
Girard, N.7
Trédaniel, J.8
Guilleminault, L.9
Gervais, R.10
-
32
-
-
84926416450
-
Circulating tumor DNA as a non-invasive substitute to metastasis biopsy for tumor genotyping and personalized medicine in a prospective trial across all tumor types
-
Lebofsky, R., Decraene, C., Bernard, V., Kamal, M., Blin, A., Leroy, Q., Frio, T.R., Pierron, G., Callens, C., Bieche, I., et al. Circulating tumor DNA as a non-invasive substitute to metastasis biopsy for tumor genotyping and personalized medicine in a prospective trial across all tumor types. Mol. Oncol. 2015, 9, 783-790.
-
(2015)
Mol. Oncol
, vol.9
, pp. 783-790
-
-
Lebofsky, R.1
Decraene, C.2
Bernard, V.3
Kamal, M.4
Blin, A.5
Leroy, Q.6
Frio, T.R.7
Pierron, G.8
Callens, C.9
Bieche, I.10
-
33
-
-
84871780523
-
Toward improved understanding of the ethical and clinical issues surrounding mandatory research biopsies
-
Peppercorn, J. Toward improved understanding of the ethical and clinical issues surrounding mandatory research biopsies. J. Clin. Oncol. 2013, 31, 1-2.
-
(2013)
J. Clin. Oncol
, vol.31
, pp. 1-2
-
-
Peppercorn, J.1
-
34
-
-
84881431073
-
Circulating tumor cells and DNA as liquid biopsies
-
Heitzer, E., Auer, M., Ulz, P., Geigl, J.B., Speicher, M.R. Circulating tumor cells and DNA as liquid biopsies. Genome Med. 2013, 5, 73.
-
(2013)
Genome Med
, vol.5
, pp. 73
-
-
Heitzer, E.1
Auer, M.2
Ulz, P.3
Geigl, J.B.4
Speicher, M.R.5
-
35
-
-
84942888495
-
Circulating Tumor DNA Outperforms Circulating Tumor Cells for KRAS Mutation Detection in Thoracic Malignancies
-
Freidin, M.B., Freydina, D.V., Leung, M., Fernandez, A.M., Nicholson, A.G., Lim, E. Circulating Tumor DNA Outperforms Circulating Tumor Cells for KRAS Mutation Detection in Thoracic Malignancies. Clin. Chem. 2015, 61, 1299-1304.
-
(2015)
Clin. Chem
, vol.61
, pp. 1299-1304
-
-
Freidin, M.B.1
Freydina, D.V.2
Leung, M.3
Fernandez, A.M.4
Nicholson, A.G.5
Lim, E.6
-
36
-
-
85015470519
-
Circulating free DNA in the management of breast cancer
-
Shaw, J.A., Stebbing, J. Circulating free DNA in the management of breast cancer. Ann. Transl. Med. 2014, 2, 3.
-
(2014)
Ann. Transl. Med
, vol.2
, pp. 3
-
-
Shaw, J.A.1
Stebbing, J.2
-
37
-
-
84920394727
-
Improved overall survival in melanoma with combined dabrafenib and trametinib
-
Robert, C., Karaszewska, B., Schachter, J., Rutkowski, P., Mackiewicz, A., Stroiakovski, D., Lichinitser, M., Dummer, R., Grange, F., Mortier, L., et al. Improved overall survival in melanoma with combined dabrafenib and trametinib. N. Engl. J. Med. 2015, 372, 30-39.
-
(2015)
N. Engl. J. Med
, vol.372
, pp. 30-39
-
-
Robert, C.1
Karaszewska, B.2
Schachter, J.3
Rutkowski, P.4
Mackiewicz, A.5
Stroiakovski, D.6
Lichinitser, M.7
Dummer, R.8
Grange, F.9
Mortier, L.10
-
38
-
-
84857502654
-
Erlotinib versus standard chemotherapy as first-line treatment for European patients with advanced EGFR mutation-positive non-small-cell lung cancer [EURTAC]: A multicentre, open-label, randomised phase 3 trial
-
Rosell, R., Carcereny, E., Gervais, R., Vergnenegre, A., Massuti, B., Felip, E., Palmero, R., Garcia-Gomez, R., Pallares, C., Sanchez, J.M., et al. Erlotinib versus standard chemotherapy as first-line treatment for European patients with advanced EGFR mutation-positive non-small-cell lung cancer [EURTAC]: A multicentre, open-label, randomised phase 3 trial. Lancet Oncol. 2012, 13, 239-246.
-
(2012)
Lancet Oncol
, vol.13
, pp. 239-246
-
-
Rosell, R.1
Carcereny, E.2
Gervais, R.3
Vergnenegre, A.4
Massuti, B.5
Felip, E.6
Palmero, R.7
Garcia-Gomez, R.8
Pallares, C.9
Sanchez, J.M.10
-
39
-
-
84905033858
-
Cancer biomarkers: Written in blood
-
Yong, E. Cancer biomarkers: Written in blood. Nature 2014, 511, 524-526.
-
(2014)
Nature
, vol.511
, pp. 524-526
-
-
Yong, E.1
-
40
-
-
84940416459
-
Mutation tracking in circulating tumor DNA predicts relapse in early breast cancer
-
302ra133
-
Garcia-Murillas, I., Schiavon, G., Weigelt, B., Ng, C., Hrebien, S., Cutts, R.J., Cheang, M., Osin, P., Nerurkar, A., Kozarewa, I., et al. Mutation tracking in circulating tumor DNA predicts relapse in early breast cancer. Sci. Transl. Med. 2015, 7, 302ra133.
-
(2015)
Sci. Transl. Med
, vol.7
-
-
Garcia-Murillas, I.1
Schiavon, G.2
Weigelt, B.3
Ng, C.4
Hrebien, S.5
Cutts, R.J.6
Cheang, M.7
Osin, P.8
Nerurkar, A.9
Kozarewa, I.10
-
41
-
-
84927615702
-
Circulating free DNA as biomarker and source for mutation detection in metastatic colorectal cancer
-
Spindler, K.L., Pallisgaard, N., Andersen, R.F., Brandslund, I., Jakobsen, A. Circulating free DNA as biomarker and source for mutation detection in metastatic colorectal cancer. PLoS ONE 2015, 10, e0108247.
-
(2015)
Plos ONE
, vol.10
-
-
Spindler, K.L.1
Pallisgaard, N.2
Ersen, R.F.3
Brandslund, I.4
Jakobsen, A.5
-
42
-
-
84900410805
-
Personalized ovarian cancer disease surveillance and detection of candidate therapeutic drug target in circulating tumor DNA
-
Martignetti, J.A., Camacho-Vanegas, O., Priedigkeit, N., Camacho, C., Pereira, E., Lin, L., Garnar-Wortzel, L., Miller, D., Losic, B., Shah, H., et al. Personalized ovarian cancer disease surveillance and detection of candidate therapeutic drug target in circulating tumor DNA. Neoplasia 2014, 16, 97-103.
-
(2014)
Neoplasia
, vol.16
, pp. 97-103
-
-
Martignetti, J.A.1
Camacho-Vanegas, O.2
Priedigkeit, N.3
Camacho, C.4
Pereira, E.5
Lin, L.6
Garnar-Wortzel, L.7
Miller, D.8
Losic, B.9
Shah, H.10
-
43
-
-
84894028183
-
Ovarian cancer screening—Current status, future directions
-
Menon, U., Griffin, M., Gentry-Maharaj, A. Ovarian cancer screening—Current status, future directions. Gynecol. Oncol. 2014, 132, 490-495.
-
(2014)
Gynecol. Oncol
, vol.132
, pp. 490-495
-
-
Menon, U.1
Griffin, M.2
Gentry-Maharaj, A.3
-
44
-
-
84955671066
-
Prognostic value of BRAF and KRAS mutation status in stage II and III microsatellite instable colon cancers
-
De Cuba, E.M., Snaebjornsson, P., Heideman, D.A., van Grieken, N.C., Bosch, L.J., Fijneman, R.J., Belt, E., Bril, H., Stockmann, H.B., Hooijberg, E., et al. Prognostic value of BRAF and KRAS mutation status in stage II and III microsatellite instable colon cancers. Int. J. Cancer 2016, 138, 1139-1145.
-
(2016)
Int. J. Cancer
, vol.138
, pp. 1139-1145
-
-
De Cuba, E.M.1
Snaebjornsson, P.2
Heideman, D.A.3
Van Grieken, N.C.4
Bosch, L.J.5
Fijneman, R.J.6
Belt, E.7
Bril, H.8
Stockmann, H.B.9
Hooijberg, E.10
-
45
-
-
84957063275
-
Tumor Heterogeneity and Lesion-Specific Response to Targeted Therapy in Colorectal Cancer
-
Russo, M., Siravegna, G., Blaszkowsky, L.S., Corti, G., Crisafulli, G., Ahronian, L.G., Mussolin, B., Kwak, E.L., Buscarino, M., Lazzari, L., et al. Tumor Heterogeneity and Lesion-Specific Response to Targeted Therapy in Colorectal Cancer. Cancer Discov. 2016, 6, 147-153.
-
(2016)
Cancer Discov
, vol.6
, pp. 147-153
-
-
Russo, M.1
Siravegna, G.2
Blaszkowsky, L.S.3
Corti, G.4
Crisafulli, G.5
Ahronian, L.G.6
Mussolin, B.7
Kwak, E.L.8
Buscarino, M.9
Lazzari, L.10
-
46
-
-
84952638610
-
Liquid biopsies for solid tumors: Understanding tumor heterogeneity and real time monitoring of early resistance to targeted therapies
-
Esposito, A., Criscitiello, C., Locatelli, M., Milano, M., Curigliano, G. Liquid biopsies for solid tumors: Understanding tumor heterogeneity and real time monitoring of early resistance to targeted therapies. Pharmacol. Ther. 2016, 157, 120-124.
-
(2016)
Pharmacol. Ther
, vol.157
, pp. 120-124
-
-
Esposito, A.1
Criscitiello, C.2
Locatelli, M.3
Milano, M.4
Curigliano, G.5
-
47
-
-
84875520648
-
Analysis of circulating tumor DNA to monitor metastatic breast cancer
-
Dawson, S.J., Tsui, D.W., Murtaza, M., Biggs, H., Rueda, O.M., Chin, S.F., Dunning, M.J., Gale, D., Forshew, T., Mahler-Araujo, B., et al. Analysis of circulating tumor DNA to monitor metastatic breast cancer. N. Engl. J. Med. 2013, 368, 1199-1209.
-
(2013)
N. Engl. J. Med
, vol.368
, pp. 1199-1209
-
-
Dawson, S.J.1
Tsui, D.W.2
Murtaza, M.3
Biggs, H.4
Rueda, O.M.5
Chin, S.F.6
Dunning, M.J.7
Gale, D.8
Forshew, T.9
Mahler-Araujo, B.10
-
48
-
-
84938414305
-
Serial monitoring of circulating tumor DNA in patients with primary breast cancer for detection of occult metastatic disease
-
Olsson, E., Winter, C., George, A., Chen, Y., Howlin, J., Tang, M.H., Dahlgren, M., Schulz, R., Grabau, D., van Westen, D., et al. Serial monitoring of circulating tumor DNA in patients with primary breast cancer for detection of occult metastatic disease. EMBO Mol. Med. 2015, 7, 1034-1047.
-
(2015)
EMBO Mol. Med
, vol.7
, pp. 1034-1047
-
-
Olsson, E.1
Winter, C.2
George, A.3
Chen, Y.4
Howlin, J.5
Tang, M.H.6
Dahlgren, M.7
Schulz, R.8
Grabau, D.9
Van Westen, D.10
-
49
-
-
84962222188
-
Detection of T790M, the acquired resistance EGFR mutation, by tumor biopsy versus noninvasive blood-based analyses
-
Sundaresan, T.K., Sequist, L.V., Heymach, J.V., Riely, G.J., Jänne, P.A., Koch, W.H., Sullivan, J.P., Fox, D.B., Maher, R., Muzikansky, A., et al. Detection of T790M, the acquired resistance EGFR mutation, by tumor biopsy versus noninvasive blood-based analyses. Clin. Cancer Res. 2016, 22, 1103-1110.
-
(2016)
Clin. Cancer Res
, vol.22
, pp. 1103-1110
-
-
Sundaresan, T.K.1
Sequist, L.V.2
Heymach, J.V.3
Riely, G.J.4
Jänne, P.A.5
Koch, W.H.6
Sullivan, J.P.7
Fox, D.B.8
Maher, R.9
Muzikansky, A.10
-
50
-
-
84989812396
-
The Role of Next-Generation Sequencing in Castration-Resistant Prostate Cancer Treatment
-
Hovelson, D.H., Tomlins, S.A. The Role of Next-Generation Sequencing in Castration-Resistant Prostate Cancer Treatment. Cancer J. 2016, 22, 357-361.
-
(2016)
Cancer J
, vol.22
, pp. 357-361
-
-
Hovelson, D.H.1
Tomlins, S.A.2
-
51
-
-
84970027825
-
Prostate cancer: Genetics of mCRPC tracked in ctDNA
-
Sidaway, P. Prostate cancer: Genetics of mCRPC tracked in ctDNA. Nat. Rev. Urol. 2016.
-
(2016)
Nat. Rev. Urol
-
-
Sidaway, P.1
-
52
-
-
84923869755
-
Brain tumor mutations detected in cerebral spinal fluid
-
Pan, W., Gu, W., Nagpal, S., Gephart, M.H., Quake, S.R. Brain tumor mutations detected in cerebral spinal fluid. Clin. Chem. 2015, 61, 514-522.
-
(2015)
Clin. Chem
, vol.61
, pp. 514-522
-
-
Pan, W.1
Gu, W.2
Nagpal, S.3
Gephart, M.H.4
Quake, S.R.5
-
53
-
-
0036624987
-
DNA alterations in body fluids as molecular tumor markers for urological malignancies
-
Goessl, C., Muller, M., Straub, B., Miller, K. DNA alterations in body fluids as molecular tumor markers for urological malignancies. Eur. Urol. 2002, 41, 668-676.
-
(2002)
Eur. Urol
, vol.41
, pp. 668-676
-
-
Goessl, C.1
Muller, M.2
Straub, B.3
Miller, K.4
-
54
-
-
85012935571
-
Detection of EGFR T790M mutation in urinary circulating tumor DNA from metastatic non-small cell lung cancer patients
-
Husain, H., Kosco, K., Guerrero, S., Lu, T.T., Vibat, C.R.T., Erlander, M.G., Melnikova, V. Detection of EGFR T790M mutation in urinary circulating tumor DNA from metastatic non-small cell lung cancer patients. Ann. Oncol. 2015, 26, i10.
-
(2015)
Ann. Oncol
, vol.26
, pp. i10
-
-
Husain, H.1
Kosco, K.2
Guerrero, S.3
Lu, T.T.4
Vibat, C.R.T.5
Erlander, M.G.6
Melnikova, V.7
-
55
-
-
52249107130
-
Detection of mutated K-ras DNA in urine, plasma, and serum of patients with colorectal carcinoma or adenomatous polyps
-
Su, Y.H., Wang, M., Brenner, D.E., Norton, P.A., Block, T.M. Detection of mutated K-ras DNA in urine, plasma, and serum of patients with colorectal carcinoma or adenomatous polyps. Ann. N. Y. Acad. Sci. 2008, 1137, 197-206.
-
(2008)
Ann. N. Y. Acad. Sci.
, vol.1137
, pp. 197-206
-
-
Su, Y.H.1
Wang, M.2
Brenner, D.E.3
Norton, P.A.4
Block, T.M.5
-
56
-
-
84937611698
-
Detection of somatic mutations and HPV in the saliva and plasma of patients with head and neck squamous cell carcinomas
-
293ra104
-
Wang, Y., Springer, S., Mulvey, C.L., Silliman, N., Schaefer, J., Sausen, M., James, N., Rettig, E.M., Guo, T., Pickering, C.R., et al. Detection of somatic mutations and HPV in the saliva and plasma of patients with head and neck squamous cell carcinomas. Sci. Transl. Med. 2015, 7, 293ra104.
-
(2015)
Sci. Transl. Med
, vol.7
-
-
Wang, Y.1
Springer, S.2
Mulvey, C.L.3
Silliman, N.4
Schaefer, J.5
Sausen, M.6
James, N.7
Rettig, E.M.8
Guo, T.9
Pickering, C.R.10
-
57
-
-
84902147985
-
Detection of EGFR mutational profile by direct dideoxy sequencing in cytology and non-cytology biopsy samples
-
Leslie, C., Giardina, T., Carrello, A., Spagnolo, D.V., Amanuel, B. Detection of EGFR mutational profile by direct dideoxy sequencing in cytology and non-cytology biopsy samples. Pathology 2014, 46, 283-288.
-
(2014)
Pathology
, vol.46
, pp. 283-288
-
-
Leslie, C.1
Giardina, T.2
Carrello, A.3
Spagnolo, D.V.4
Amanuel, B.5
-
58
-
-
33750190059
-
Cell-free DNA concentration in pleural fluid and serum: Quantitative approach and potential prognostic factor in patients with cancer and pleural effusions
-
Benlloch, S., Martí-Ciriquián, J.L., Galbis-Caravajal, J.M., Martín, C., Sánchez-Payá, J., Rodríguez-Paniagua, J.M., Romero, S., Massutí, B. Cell-free DNA concentration in pleural fluid and serum: Quantitative approach and potential prognostic factor in patients with cancer and pleural effusions. Clin. Lung Cancer 2006, 8, 140-145.
-
(2006)
Clin. Lung Cancer
, vol.8
, pp. 140-145
-
-
Benlloch, S.1
Martí-Ciriquián, J.L.2
Galbis-Caravajal, J.M.3
Martín, C.4
Sánchez-Payá, J.5
Rodríguez-Paniagua, J.M.6
Romero, S.7
Massutí, B.8
-
59
-
-
84929413365
-
Clinical application of DNA ploidy to cervical cancer screening: A review
-
Garner, D. Clinical application of DNA ploidy to cervical cancer screening: A review. World J. Clin. Oncol. 2014, 55, 931-965.
-
(2014)
World J. Clin. Oncol
, vol.55
, pp. 931-965
-
-
Garner, D.1
-
60
-
-
84910002265
-
Accuracy of early detection of colorectal tumours by stool methylation markers: A meta-analysis
-
Zhang, H., Qi, J., Wu, Y.Q., Zhang, P., Jiang, J., Wang, Q.X., Zhu, Y.Q. Accuracy of early detection of colorectal tumours by stool methylation markers: A meta-analysis. World J. Gastroenterol. 2014, 20, 14040-14050.
-
(2014)
World J. Gastroenterol
, vol.20
, pp. 14040-14050
-
-
Zhang, H.1
Qi, J.2
Wu, Y.Q.3
Zhang, P.4
Jiang, J.5
Wang, Q.X.6
Zhu, Y.Q.7
-
61
-
-
84942519785
-
Diagnostic accuracy of noninvasive genotyping of EGFR in lung cancer patients by deep sequencing of plasma cell-free DNA
-
Uchida, J., Kato, K., Kukita, Y., Kumagai, T., Nishino, K., Daga, H., Nagatomo, I., Inoue, T., Kimura, M., Oba, S., et al. Diagnostic accuracy of noninvasive genotyping of EGFR in lung cancer patients by deep sequencing of plasma cell-free DNA. Clin. Chem. 2015, 61, 1191-1196.
-
(2015)
Clin. Chem
, vol.61
, pp. 1191-1196
-
-
Uchida, J.1
Kato, K.2
Kukita, Y.3
Kumagai, T.4
Nishino, K.5
Daga, H.6
Nagatomo, I.7
Inoue, T.8
Kimura, M.9
Oba, S.10
-
63
-
-
84903218109
-
An ultrasensitive method for quantitating circulating tumor DNA with broad patient coverage
-
Newman, A.M., Bratman, S.V., To, J., Wynne, J.F., Eclov, N.C.W., Modlin, L.A., Liu, C.L., Neal, J.W., Wakelee, H.A., Merritt, R.E., et al. An ultrasensitive method for quantitating circulating tumor DNA with broad patient coverage. Nat. Med. 2014, 20, 548-554.
-
(2014)
Nat. Med
, vol.20
, pp. 548-554
-
-
Newman, A.M.1
Bratman, S.V.2
To, J.3
Wynne, J.F.4
Eclov, N.C.W.5
Modlin, L.A.6
Liu, C.L.7
Neal, J.W.8
Wakelee, H.A.9
Merritt, R.E.10
-
64
-
-
85015462482
-
Current challenges for detection of circulating tumor cells and cell-free circulating nucleic acids, and their characterization in non-small cell lung carcinoma patients. What is the best blood substrate for personalized medicine
-
Ilie, M., Hofman, V., Long, E., Bordone, O., Selva, E., Washetine, K., Marquette, C.H., Hofman, P. Current challenges for detection of circulating tumor cells and cell-free circulating nucleic acids, and their characterization in non-small cell lung carcinoma patients. What is the best blood substrate for personalized medicine? Ann. Transl. Med. 2014, 2, 107.
-
(2014)
Ann. Transl. Med
, vol.2
, pp. 107
-
-
Ilie, M.1
Hofman, V.2
Long, E.3
Bordone, O.4
Selva, E.5
Washetine, K.6
Marquette, C.H.7
Hofman, P.8
-
65
-
-
84993963528
-
35O_PR Investigating the utility of circulating-free tumor DNA(CtDNA) in plasma for the detection of epidermal growth factor receptor(EGFR) mutation status in European and Japanese patients (PTS) with advanced non-small cell lung cancer(ANSCLC): Assess study
-
Reck, M., Hagiwara, K., Han, B., Tjulandin, S., Grohe, C., Yokoi, T., Morabito, A., McCormack, R., Ratcliffe, M., Normanno, N. 35O_PR Investigating the utility of circulating-free tumor DNA(ctDNA) in plasma for the detection of epidermal growth factor receptor(EGFR) mutation status in European and Japanese patients (PTS) with advanced non-small cell lung cancer(ANSCLC): Assess study. Ann. Oncol. 2015, 26, i58-i59.
-
(2015)
Ann. Oncol.
, vol.26
, pp. i58-i59
-
-
Reck, M.1
Hagiwara, K.2
Han, B.3
Tjulandin, S.4
Grohe, C.5
Yokoi, T.6
Morabito, A.7
McCormack, R.8
Ratcliffe, M.9
Normanno, N.10
-
66
-
-
84888581141
-
Non-coding RNAs in hepatitis C-induced hepatocellular carcinoma: Dysregulation and implications for early detection, diagnosis and therapy
-
Hou, W., Bonkovsky, H.L. Non-coding RNAs in hepatitis C-induced hepatocellular carcinoma: Dysregulation and implications for early detection, diagnosis and therapy. World J. Gastroenterol. 2013, 19, 7836-7845.
-
(2013)
World J. Gastroenterol
, vol.19
, pp. 7836-7845
-
-
Hou, W.1
Bonkovsky, H.L.2
-
67
-
-
84937958159
-
Circulating RNAs as new biomarkers for detecting pancreatic cancer
-
Kishikawa, T., Otsuka, M., Ohno, M., Yoshikawa, T., Takata, A., Koike, K. Circulating RNAs as new biomarkers for detecting pancreatic cancer. World J. Gastroenterol. 2015, 21, 8527-8540.
-
(2015)
World J. Gastroenterol
, vol.21
, pp. 8527-8540
-
-
Kishikawa, T.1
Otsuka, M.2
Ohno, M.3
Yoshikawa, T.4
Takata, A.5
Koike, K.6
-
68
-
-
84952327678
-
A novel methylation derivatization method for
-
Lehmann, M.M., Fischer, M., Blees, J., Zech, M., Siegwolf, R.T., Saurer, M. A novel methylation derivatization method for δ18O analysis of individual carbohydrates by gas chromatography/pyrolysis-isotope ratio mass spectrometry. Rapid Commun. Mass Spectrom. 2016, 30, 221-229.
-
(2016)
Rapid Commun. Mass Spectrom
, vol.30
, pp. 221-229
-
-
Lehmann, M.M.1
Fischer, M.2
Blees, J.3
Zech, M.4
Siegwolf, R.T.5
Saurer, M.6
-
69
-
-
84920937459
-
Ultra-sensitive liquid biopsy of circulating extracellular vesicles using ExoScreen
-
Yoshioka, Y., Kosaka, N., Konishi, Y., Ohta, H., Okamoto, H., Sonoda, H., Nonaka, R., Yamamoto, H., Ishii, H., Mori, M., et al. Ultra-sensitive liquid biopsy of circulating extracellular vesicles using ExoScreen. Nat. Commun. 2014, 5, 3591.
-
(2014)
Nat. Commun
, vol.5
, pp. 3591
-
-
Yoshioka, Y.1
Kosaka, N.2
Konishi, Y.3
Ohta, H.4
Okamoto, H.5
Sonoda, H.6
Nonaka, R.7
Yamamoto, H.8
Ishii, H.9
Mori, M.10
|