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Volumn 22, Issue 5, 2016, Pages 357-361

The role of next-generation sequencing in castration-resistant prostate cancer treatment

Author keywords

Cell free DNA; Circulating tumor cells; Exome sequencing; Molecular landscape; PARP inhibitor; Small cell carcinoma; Transcriptome sequencing

Indexed keywords

ANTIANDROGEN THERAPY; CANCER PROGNOSIS; CANCER SCREENING; CANCER THERAPY; CASTRATION RESISTANT PROSTATE CANCER; CIRCULATING TUMOR CELL; DISEASE COURSE; GENE EXPRESSION PROFILING; GENETIC HETEROGENEITY; GENOMICS; HUMAN; MALE; NEUROENDOCRINE TUMOR; NEXT GENERATION SEQUENCING; PERSONALIZED MEDICINE; PRIORITY JOURNAL; PROSTATE CANCER; REVIEW; TRANSCRIPTOMICS; CLINICAL TRIAL (TOPIC); GENETICS; HIGH THROUGHPUT SEQUENCING; PROCEDURES; PROSTATIC NEOPLASMS, CASTRATION-RESISTANT;

EID: 84989812396     PISSN: 15289117     EISSN: 1540336X     Source Type: Journal    
DOI: 10.1097/PPO.0000000000000217     Document Type: Review
Times cited : (13)

References (55)
  • 1
    • 84930225081 scopus 로고    scopus 로고
    • Integrative clinical genomics of advanced prostate cancer
    • Robinson D, Van Allen EM, Wu YM, et al. Integrative clinical genomics of advanced prostate cancer. Cell. 2015; 161: 1215-1228
    • (2015) Cell , vol.161 , pp. 1215-1228
    • Robinson, D.1    Van Allen, E.M.2    Wu, Y.M.3
  • 2
    • 84946195510 scopus 로고    scopus 로고
    • The molecular taxonomy of primary prostate cancer
    • Cancer Genome Atlas Research Network
    • Cancer Genome Atlas Research Network. The molecular taxonomy of primary prostate cancer. Cell 2015; 163: 1011-1025
    • (2015) Cell , vol.163 , pp. 1011-1025
  • 3
    • 84928405167 scopus 로고    scopus 로고
    • The evolutionary history of lethal metastatic prostate cancer
    • GundemG, Van Loo P, Kremeyer B, et al. The evolutionary history of lethal metastatic prostate cancer. Nature. 2015; 520: 353-357
    • (2015) Nature , vol.520 , pp. 353-357
    • GundemG Van Loo, P.1    Kremeyer, B.2
  • 4
    • 84957623685 scopus 로고    scopus 로고
    • Divergent clonal evolution of castration-resistant neuroendocrine prostate cancer
    • Beltran H, Prandi D, Mosquera JM, et al. Divergent clonal evolution of castration-resistant neuroendocrine prostate cancer. Nat Med. 2016; 22: 298-305
    • (2016) Nat Med , vol.22 , pp. 298-305
    • Beltran, H.1    Prandi, D.2    Mosquera, J.M.3
  • 5
    • 84959255550 scopus 로고    scopus 로고
    • Substantial interindividual and limited intraindividual genomic diversity among tumors from men with metastatic prostate cancer
    • Kumar A, Coleman I, Morrissey C, et al. Substantial interindividual and limited intraindividual genomic diversity among tumors from men with metastatic prostate cancer. Nat Med. 2016; 22: 369-378
    • (2016) Nat Med , vol.22 , pp. 369-378
    • Kumar, A.1    Coleman, I.2    Morrissey, C.3
  • 6
    • 84863723010 scopus 로고    scopus 로고
    • The mutational landscape of lethal castration-resistant prostate cancer
    • Grasso CS, Wu YM, Robinson DR, et al. The mutational landscape of lethal castration-resistant prostate cancer. Nature. 2012; 487: 239-243
    • (2012) Nature , vol.487 , pp. 239-243
    • Grasso, C.S.1    Wu, Y.M.2    Robinson, D.R.3
  • 7
    • 84925231126 scopus 로고    scopus 로고
    • RNA biomarkers associated with metastatic progression in prostate cancer: A multi-institutional high-throughput analysis of SChLAP1
    • Prensner JR, Zhao S, Erho N, et al. RNA biomarkers associated with metastatic progression in prostate cancer: a multi-institutional high-throughput analysis of SChLAP1. Lancet Oncol. 2014; 15: 1469-1480
    • (2014) Lancet Oncol , vol.15 , pp. 1469-1480
    • Prensner, J.R.1    Zhao, S.2    Erho, N.3
  • 8
    • 84924655117 scopus 로고    scopus 로고
    • Identification of a candidate prognostic gene signature by transcriptome analysis of matched pre- and posttreatment prostatic biopsies from patients with advanced prostate cancer
    • Rajan P, Stockley J, Sudbery IM, et al. Identification of a candidate prognostic gene signature by transcriptome analysis of matched pre- and posttreatment prostatic biopsies from patients with advanced prostate cancer. BMC Cancer. 2014; 14: 977
    • (2014) BMC Cancer , vol.14 , pp. 977
    • Rajan, P.1    Stockley, J.2    Sudbery, I.M.3
  • 9
    • 84945395861 scopus 로고    scopus 로고
    • Transcriptome sequencing reveals PCAT5 as a novel ERG-regulated long noncoding RNA in prostate cancer
    • Ylipaa A, Kivinummi K, Kohvakka A, et al. Transcriptome sequencing reveals PCAT5 as a novel ERG-regulated long noncoding RNA in prostate cancer. Cancer Res. 2015; 75: 4026-4031
    • (2015) Cancer Res , vol.75 , pp. 4026-4031
    • Ylipaa, A.1    Kivinummi, K.2    Kohvakka, A.3
  • 10
    • 84907057471 scopus 로고    scopus 로고
    • AR-V7 and resistance to enzalutamide and abiraterone in prostate cancer
    • Antonarakis ES, Lu C, Wang H, et al. AR-V7 and resistance to enzalutamide and abiraterone in prostate cancer. N Engl J Med. 2014; 371: 1028-1038
    • (2014) N Engl J Med , vol.371 , pp. 1028-1038
    • Antonarakis, E.S.1    Lu, C.2    Wang, H.3
  • 11
    • 84876064523 scopus 로고    scopus 로고
    • Targeted next-generation sequencing of advanced prostate cancer identifies potential therapeutic targets and disease heterogeneity
    • Beltran H, Yelensky R, Frampton GM, et al. Targeted next-generation sequencing of advanced prostate cancer identifies potential therapeutic targets and disease heterogeneity. Eur Urol. 2013; 63: 920-926
    • (2013) Eur Urol , vol.63 , pp. 920-926
    • Beltran, H.1    Yelensky, R.2    Frampton, G.M.3
  • 12
    • 84983535287 scopus 로고    scopus 로고
    • Development and validation of a scalable next-generation sequencing system for assessing relevant somatic variants in solid tumors
    • Hovelson DH, McDaniel AS, Cani AK, et al. Development and validation of a scalable next-generation sequencing system for assessing relevant somatic variants in solid tumors. Neoplasia. 2015; 17: 385-399
    • (2015) Neoplasia , vol.17 , pp. 385-399
    • Hovelson, D.H.1    McDaniel, A.S.2    Cani, A.K.3
  • 13
    • 84982128149 scopus 로고    scopus 로고
    • A pilot study of clinical targeted next generation sequencing for prostate cancer: Consequences for treatment and genetic counseling
    • Cheng HH, Klemfuss N, Montgomery B, et al. A pilot study of clinical targeted next generation sequencing for prostate cancer: consequences for treatment and genetic counseling. Prostate. 2016
    • (2016) Prostate
    • Cheng, H.H.1    Klemfuss, N.2    Montgomery, B.3
  • 14
    • 84941002648 scopus 로고    scopus 로고
    • The use of exome capture RNA-Seq for highly degraded RNA with application to clinical cancer sequencing
    • Cieslik M, Chugh R, Wu YM, et al. The use of exome capture RNA-Seq for highly degraded RNA with application to clinical cancer sequencing. Genome Res. 2015; 25: 1372-1381
    • (2015) Genome Res , vol.25 , pp. 1372-1381
    • Cieslik, M.1    Chugh, R.2    Wu, Y.M.3
  • 15
    • 84902148239 scopus 로고    scopus 로고
    • Whole-exome sequencing and clinical interpretation of formalin-fixed, paraffin-embedded tumor samples to guide precision cancer medicine
    • Van Allen EM, Wagle N, Stojanov P, et al. Whole-exome sequencing and clinical interpretation of formalin-fixed, paraffin-embedded tumor samples to guide precision cancer medicine. Nat Med. 2014; 20(6): 682-688
    • (2014) Nat Med , vol.20 , Issue.6 , pp. 682-688
    • Van Allen, E.M.1    Wagle, N.2    Stojanov, P.3
  • 16
    • 84873370892 scopus 로고    scopus 로고
    • New strategies in prostate cancer: Translating genomics into the clinic
    • Beltran H, Rubin MA. New strategies in prostate cancer: Translating genomics into the clinic. Clin Cancer Res. 2013; 19: 517-523
    • (2013) Clin Cancer Res , vol.19 , pp. 517-523
    • Beltran, H.1    Rubin, M.A.2
  • 17
    • 84947245381 scopus 로고    scopus 로고
    • Plasma AR and abiraterone-resistant prostate cancer
    • Romanel A, Gasi Tandefelt D, Conteduca V, et al. Plasma AR and abiraterone-resistant prostate cancer. Sci Transl Med. 2015; 7: 312re310
    • (2015) Sci Transl Med , vol.7 , pp. 312re310
    • Romanel, A.1    Gasi Tandefelt, D.2    Conteduca, V.3
  • 18
    • 27344451557 scopus 로고    scopus 로고
    • Recurrent fusion of TMPRSS2 and ETS transcription factor genes in prostate cancer
    • Tomlins SA, Rhodes DR, Perner S, et al. Recurrent fusion of TMPRSS2 and ETS transcription factor genes in prostate cancer. Science. 2005; 310: 644-648
    • (2005) Science , vol.310 , pp. 644-648
    • Tomlins, S.A.1    Rhodes, D.R.2    Perner, S.3
  • 19
    • 44449139593 scopus 로고    scopus 로고
    • The role of SPINK1 in ETS rearrangement-negative prostate cancers
    • Tomlins SA, Rhodes DR, Yu J, et al. The role of SPINK1 in ETS rearrangement-negative prostate cancers. Cancer Cell. 2008; 13: 519-528
    • (2008) Cancer Cell , vol.13 , pp. 519-528
    • Tomlins, S.A.1    Rhodes, D.R.2    Yu, J.3
  • 20
    • 84933510527 scopus 로고    scopus 로고
    • Androgen receptor gene aberrations in circulating cell-free DNA: Biomarkers of therapeutic resistance in castrationresistant prostate cancer
    • AzadAA, Volik SV, WyattAW, et al. Androgen receptor gene aberrations in circulating cell-free DNA: biomarkers of therapeutic resistance in castrationresistant prostate cancer. Clin Cancer Res. 2015; 21: 2315-2324
    • (2015) Clin Cancer Res , vol.21 , pp. 2315-2324
    • Azad, A.A.1    Volik, S.V.2    Wyatt, A.W.3
  • 21
    • 84907285681 scopus 로고    scopus 로고
    • Tumor clone dynamics in lethal prostate cancer
    • 254ra125
    • Carreira S, Romanel A, Goodall J, et al. Tumor clone dynamics in lethal prostate cancer. Sci Transl Med. 2014; 6: 254ra125
    • (2014) Sci Transl Med , vol.6
    • Carreira, S.1    Romanel, A.2    Goodall, J.3
  • 22
    • 85013175347 scopus 로고    scopus 로고
    • Genomic alterations in cell-free DNA and enzalutamide resistance in castration-resistant prostate cancer
    • published online ahead of print May 5 2016]
    • Wyatt AW, Azad AA, Volik SV, et al. Genomic alterations in cell-free DNA and enzalutamide resistance in castration-resistant prostate cancer [published online ahead of print May 5, 2016]. In: JAMA Oncol. 2016
    • (2016) JAMA Oncol
    • Wyatt, A.W.1    Azad, A.A.2    Volik, S.V.3
  • 23
    • 84956577962 scopus 로고    scopus 로고
    • Functional analysis of androgen receptor mutations that confer anti-Androgen resistance identified in circulating cell-free DNA from prostate cancer patients
    • Lallous N, Volik SV, Awrey S, et al. Functional analysis of androgen receptor mutations that confer anti-Androgen resistance identified in circulating cell-free DNA from prostate cancer patients. Genome Biol. 2016; 17: 10
    • (2016) Genome Biol , vol.17 , pp. 10
    • Lallous, N.1    Volik, S.V.2    Awrey, S.3
  • 24
    • 84975744385 scopus 로고    scopus 로고
    • Whole-genome plasma sequencing reveals focal amplifications as a driving force in metastatic prostate cancer
    • Ulz P, Belic J, Graf R, et al. Whole-genome plasma sequencing reveals focal amplifications as a driving force in metastatic prostate cancer. Nat Commun. 2016; 7: 12008
    • (2016) Nat Commun , vol.7 , pp. 12008
    • Ulz, P.1    Belic, J.2    Graf, R.3
  • 25
    • 84900333051 scopus 로고    scopus 로고
    • Whole-exome sequencing of circulating tumor cells provides a windowinto metastatic prostate cancer
    • Lohr JG, Adalsteinsson VA, Cibulskis K, et al. Whole-exome sequencing of circulating tumor cells provides a windowinto metastatic prostate cancer. Nat Biotechnol. 2014; 32: 479-484
    • (2014) Nat Biotechnol , vol.32 , pp. 479-484
    • Lohr, J.G.1    Adalsteinsson, V.A.2    Cibulskis, K.3
  • 26
    • 84942904757 scopus 로고    scopus 로고
    • RNA-Seq of single prostate CTCs implicates noncanonical Wnt signaling in antiandrogen resistance
    • Miyamoto DT, Zheng Y, Wittner BS, et al. RNA-Seq of single prostate CTCs implicates noncanonical Wnt signaling in antiandrogen resistance. Science. 2015; 349: 1351-1356
    • (2015) Science , vol.349 , pp. 1351-1356
    • Miyamoto, D.T.1    Zheng, Y.2    Wittner, B.S.3
  • 27
    • 84887429673 scopus 로고    scopus 로고
    • Tracking the clonal origin of lethal prostate cancer
    • Haffner MC, Mosbruger T, Esopi DM, et al. Tracking the clonal origin of lethal prostate cancer. J Clin Invest. 2013; 123: 4918-4922
    • (2013) J Clin Invest , vol.123 , pp. 4918-4922
    • Haffner, M.C.1    Mosbruger, T.2    Esopi, D.M.3
  • 28
    • 0036321565 scopus 로고    scopus 로고
    • Morphologic and clinical significance of multifocal prostate cancers in radical prostatectomy specimens
    • Wise AM, Stamey TA, McNeal JE, et al. Morphologic and clinical significance of multifocal prostate cancers in radical prostatectomy specimens. Urology. 2002; 60: 264-269
    • (2002) Urology , vol.60 , pp. 264-269
    • Wise, A.M.1    Stamey, T.A.2    McNeal, J.E.3
  • 29
    • 84933277410 scopus 로고    scopus 로고
    • Spatial genomic heterogeneity within localized, multifocal prostate cancer
    • Boutros PC, Fraser M, Harding NJ, et al. Spatial genomic heterogeneity within localized, multifocal prostate cancer. Nat Genet. 2015; 47: 736-745
    • (2015) Nat Genet , vol.47 , pp. 736-745
    • Boutros, P.C.1    Fraser, M.2    Harding, N.J.3
  • 30
    • 84930195799 scopus 로고    scopus 로고
    • Analysis of the genetic phylogeny of multifocal prostate cancer identifies multiple independent clonal expansions in neoplastic and morphologically normal prostate tissue
    • Cooper CS, Eeles R, Wedge DC, et al. Analysis of the genetic phylogeny of multifocal prostate cancer identifies multiple independent clonal expansions in neoplastic and morphologically normal prostate tissue. Nat Genet. 2015; 47: 367-372
    • (2015) Nat Genet , vol.47 , pp. 367-372
    • Cooper, C.S.1    Eeles, R.2    Wedge, D.C.3
  • 31
    • 67349257845 scopus 로고    scopus 로고
    • Copy number analysis indicates monoclonal origin of lethal metastatic prostate cancer
    • LiuW, Laitinen S, Khan S, et al. Copy number analysis indicates monoclonal origin of lethal metastatic prostate cancer. Nat Med. 2009; 15: 559-565
    • (2009) Nat Med , vol.15 , pp. 559-565
    • LiuW Laitinen, S.1    Khan, S.2
  • 32
    • 84926330368 scopus 로고    scopus 로고
    • Tracking the origins and drivers of subclonal metastatic expansion in prostate cancer
    • HongMK, Macintyre G, Wedge DC, et al. Tracking the origins and drivers of subclonal metastatic expansion in prostate cancer. Nat Commun. 2015; 6: 6605
    • (2015) Nat Commun , vol.6 , pp. 6605
    • Hong, M.K.1    MacIntyre, G.2    Wedge, D.C.3
  • 33
    • 84957840165 scopus 로고    scopus 로고
    • Which, when and why. Rational use of tissue-based molecular testing in localized prostate cancer
    • Ross AE, D'Amico AV, Freedland SJ. Which, when and why?. Rational use of tissue-based molecular testing in localized prostate cancer. Prostate Cancer Prostatic Dis. 2016; 19: 1-6
    • (2016) Prostate Cancer Prostatic Dis , vol.19 , pp. 1-6
    • Ross, A.E.1    D'Amico, A.V.2    Freedland, S.J.3
  • 34
    • 0037130887 scopus 로고    scopus 로고
    • Breast Cancer Linkage Consortium. Cancer incidence in BRCA1 mutation carriers
    • Thompson D, Easton DF. Breast Cancer Linkage Consortium. Cancer incidence in BRCA1 mutation carriers. J Natl Cancer Inst. 2002; 94: 1358-1365
    • (2002) J Natl Cancer Inst , vol.94 , pp. 1358-1365
    • Thompson, D.1    Easton, D.F.2
  • 35
    • 1442307845 scopus 로고    scopus 로고
    • Cancer risks for male carriers of germline mutations in BRCA1 or BRCA2: A review of the literature
    • Liede A, Karlan BY, Narod SA. Cancer risks for male carriers of germline mutations in BRCA1 or BRCA2: a review of the literature. J Clin Oncol. 2004; 22(4): 735-742
    • (2004) J Clin Oncol , vol.22 , Issue.4 , pp. 735-742
    • Liede, A.1    Karlan, B.Y.2    Narod, S.A.3
  • 36
    • 85101730023 scopus 로고    scopus 로고
    • Mutations in BRCA1 and BRCA2 and predisposition to prostate cancer
    • author reply 80
    • TischkowitzM, Eeles R.Mutations in BRCA1 and BRCA2 and predisposition to prostate cancer. Lancet. 2003; 362: 80; author reply 80
    • (2003) Lancet , vol.362 , pp. 80
    • Tischkowitz, M.1    Eeles, R.2
  • 37
    • 54049130531 scopus 로고    scopus 로고
    • The role of the BRCA2 gene in susceptibility to prostate cancer revisited
    • Ostrander EA, Udler MS. The role of the BRCA2 gene in susceptibility to prostate cancer revisited. Cancer Epidemiol Biomarkers Prev. 2008; 17: 1843-1848
    • (2008) Cancer Epidemiol Biomarkers Prev , vol.17 , pp. 1843-1848
    • Ostrander, E.A.1    Udler, M.S.2
  • 38
    • 84954376354 scopus 로고    scopus 로고
    • Prostate cancer
    • 10013
    • Attard G, Parker C, Eeles RA, et al. Prostate cancer. Lancet. 2016; 387 (10013): 70-82
    • (2016) Lancet , vol.387 , pp. 70-82
    • Attard, G.1    Parker, C.2    Eeles, R.A.3
  • 39
    • 84856176782 scopus 로고    scopus 로고
    • Germline mutations in HOXB13 and prostate-cancer risk
    • Ewing CM, Ray AM, Lange EM, et al. Germline mutations in HOXB13 and prostate-cancer risk. N Engl JMed. 2012; 366: 141-149
    • (2012) N Engl JMed , vol.366 , pp. 141-149
    • Ewing, C.M.1    Ray, A.M.2    Lange, E.M.3
  • 40
    • 84860168795 scopus 로고    scopus 로고
    • Molecular characterization of neuroendocrine prostate cancer and identification of new drug targets
    • Beltran H, Rickman DS, Park K, et al.Molecular characterization of neuroendocrine prostate cancer and identification of new drug targets. Cancer Discov. 2011; 1: 487-495
    • (2011) Cancer Discov , vol.1 , pp. 487-495
    • Beltran, H.1    Rickman, D.S.2    Park, K.3
  • 41
    • 84900836746 scopus 로고    scopus 로고
    • Proposed morphologic classification of prostate cancer with neuroendocrine differentiation
    • Epstein JI, AminMB, Beltran H, et al. Proposed morphologic classification of prostate cancer with neuroendocrine differentiation. Am J Surg Pathol. 2014; 38: 756-767
    • (2014) Am J Surg Pathol , vol.38 , pp. 756-767
    • Epstein, J.I.1    Amin, M.B.2    Beltran, H.3
  • 42
  • 43
    • 84942880558 scopus 로고    scopus 로고
    • Comprehensive serial molecular profiling of an N of 1" exceptional non-responder with metastatic prostate cancer progressing to small cell carcinoma on treatment
    • Kadakia KC, Tomlins SA, Sanghvi SK, et al. Comprehensive serial molecular profiling of an "N of 1" exceptional non-responder with metastatic prostate cancer progressing to small cell carcinoma on treatment. J Hematol Oncol. 2015; 8: 109
    • (2015) J Hematol Oncol , vol.8 , pp. 109
    • Kadakia, K.C.1    Tomlins, S.A.2    Sanghvi, S.K.3
  • 44
    • 84938054007 scopus 로고    scopus 로고
    • Integrative molecular profiling of routine clinical prostate cancer specimens
    • Grasso CS, Cani AK, Hovelson DH, et al. Integrative molecular profiling of routine clinical prostate cancer specimens. Ann Oncol. 2015; 26(6): 1110-1118
    • (2015) Ann Oncol , vol.26 , Issue.6 , pp. 1110-1118
    • Grasso, C.S.1    Cani, A.K.2    Hovelson, D.H.3
  • 45
    • 84900463472 scopus 로고    scopus 로고
    • Neuroendocrine prostate cancer: Subtypes, biology, and clinical outcomes
    • Aggarwal R, Zhang T, Small EJ, et al. Neuroendocrine prostate cancer: subtypes, biology, and clinical outcomes. J Natl Compr Cancer Netw. 2014; 12: 719-726
    • (2014) J Natl Compr Cancer Netw , vol.12 , pp. 719-726
    • Aggarwal, R.1    Zhang, T.2    Small, E.J.3
  • 46
    • 84879853237 scopus 로고    scopus 로고
    • Platinum-based chemotherapy for variant castrate-resistant prostate cancer
    • Aparicio AM, Harzstark A, Corn PG, et al. Platinum-based chemotherapy for variant castrate-resistant prostate cancer. Clin Cancer Res. 2013
    • (2013) Clin Cancer Res
    • Aparicio, A.M.1    Harzstark, A.2    Corn, P.G.3
  • 47
    • 84945470634 scopus 로고    scopus 로고
    • Molecular landscape of prostate cancer: Implications for current clinical trials
    • Khemlina G, Ikeda S, Kurzrock R. Molecular landscape of prostate cancer: implications for current clinical trials. Cancer Treat Rev. 2015; 41: 761-766
    • (2015) Cancer Treat Rev , vol.41 , pp. 761-766
    • Khemlina, G.1    Ikeda, S.2    Kurzrock, R.3
  • 48
    • 84921367731 scopus 로고    scopus 로고
    • Synthetic lethality and cancer therapy: Lessons learned from the development of PARP inhibitors
    • Lord CJ, Tutt AN, Ashworth A. Synthetic lethality and cancer therapy: lessons learned from the development of PARP inhibitors. Annu Rev Med. 2015; 66: 455-470
    • (2015) Annu Rev Med , vol.66 , pp. 455-470
    • Lord, C.J.1    Tutt, A.N.2    Ashworth, A.3
  • 49
    • 84946019429 scopus 로고    scopus 로고
    • DNA-repair defects and olaparib in metastatic prostate cancer
    • Mateo J, Carreira S, Sandhu S, et al. DNA-repair defects and olaparib in metastatic prostate cancer. N Engl JMed. 2015; 373: 1697-1708
    • (2015) N Engl JMed , vol.373 , pp. 1697-1708
    • Mateo, J.1    Carreira, S.2    Sandhu, S.3
  • 50
    • 84973100750 scopus 로고    scopus 로고
    • Translational and clinical implications of the genetic landscape of prostate cancer
    • Spratt DE, Zumsteg ZS, Feng FY, et al. Translational and clinical implications of the genetic landscape of prostate cancer. In: Nat Rev Clin Oncol. 2016
    • (2016) Nat Rev Clin Oncol
    • De, S.1    Zumsteg, Z.S.2    Feng, F.Y.3
  • 51
    • 84859154379 scopus 로고    scopus 로고
    • Beyond PSA: The next generation of prostate cancer biomarkers
    • Prensner JR, RubinMA, Wei JT, et al. Beyond PSA: The next generation of prostate cancer biomarkers. Sci Transl Med. 2012; 4: 127rv123
    • (2012) Sci Transl Med , vol.4 , pp. 127rv123
    • Prensner, J.R.1    Rubin, M.A.2    Wei, J.T.3
  • 52
    • 84887122461 scopus 로고    scopus 로고
    • The long noncoding RNA SChLAP1 promotes aggressive prostate cancer and antagonizes the SWI/SNF complex
    • Prensner JR, Iyer MK, Sahu A, et al. The long noncoding RNA SChLAP1 promotes aggressive prostate cancer and antagonizes the SWI/SNF complex. Nat Genet. 2013; 45(11): 1392-1398
    • (2013) Nat Genet , vol.45 , Issue.11 , pp. 1392-1398
    • Prensner, J.R.1    Iyer, M.K.2    Sahu, A.3
  • 53
    • 84904159704 scopus 로고    scopus 로고
    • The link between androgen receptor splice variants and castration-resistant prostate cancer
    • Sprenger CC, Plymate R. The link between androgen receptor splice variants and castration-resistant prostate cancer. Horm Cancer. 2014; 5: 207-217
    • (2014) Horm Cancer , vol.5 , pp. 207-217
    • Sprenger, C.C.1    Plymate, R.2
  • 54
    • 84900371086 scopus 로고    scopus 로고
    • Prostate cancer epigenetic biomarkers: Nextgeneration technologies
    • Valdes-Mora F, Clark SJ. Prostate cancer epigenetic biomarkers: nextgeneration technologies. Oncogene. 2015; 34: 1609-1618
    • (2015) Oncogene , vol.34 , pp. 1609-1618
    • Valdes-Mora, F.1    Clark, S.J.2
  • 55
    • 84871052080 scopus 로고    scopus 로고
    • EZH2 oncogenic activity in castrationresistant prostate cancer cells is polycomb-independent
    • Xu K, Wu ZJ, Groner AC, et al. EZH2 oncogenic activity in castrationresistant prostate cancer cells is polycomb-independent. Science. 2012; 338: 1465-1469.
    • (2012) Science , vol.338 , pp. 1465-1469
    • Xu, K.1    Wu, Z.J.2    Groner, A.C.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.