-
1
-
-
84930225081
-
Integrative clinical genomics of advanced prostate cancer
-
Robinson D, Van Allen EM, Wu YM, et al. Integrative clinical genomics of advanced prostate cancer. Cell. 2015; 161: 1215-1228
-
(2015)
Cell
, vol.161
, pp. 1215-1228
-
-
Robinson, D.1
Van Allen, E.M.2
Wu, Y.M.3
-
2
-
-
84946195510
-
The molecular taxonomy of primary prostate cancer
-
Cancer Genome Atlas Research Network
-
Cancer Genome Atlas Research Network. The molecular taxonomy of primary prostate cancer. Cell 2015; 163: 1011-1025
-
(2015)
Cell
, vol.163
, pp. 1011-1025
-
-
-
3
-
-
84928405167
-
The evolutionary history of lethal metastatic prostate cancer
-
GundemG, Van Loo P, Kremeyer B, et al. The evolutionary history of lethal metastatic prostate cancer. Nature. 2015; 520: 353-357
-
(2015)
Nature
, vol.520
, pp. 353-357
-
-
GundemG Van Loo, P.1
Kremeyer, B.2
-
4
-
-
84957623685
-
Divergent clonal evolution of castration-resistant neuroendocrine prostate cancer
-
Beltran H, Prandi D, Mosquera JM, et al. Divergent clonal evolution of castration-resistant neuroendocrine prostate cancer. Nat Med. 2016; 22: 298-305
-
(2016)
Nat Med
, vol.22
, pp. 298-305
-
-
Beltran, H.1
Prandi, D.2
Mosquera, J.M.3
-
5
-
-
84959255550
-
Substantial interindividual and limited intraindividual genomic diversity among tumors from men with metastatic prostate cancer
-
Kumar A, Coleman I, Morrissey C, et al. Substantial interindividual and limited intraindividual genomic diversity among tumors from men with metastatic prostate cancer. Nat Med. 2016; 22: 369-378
-
(2016)
Nat Med
, vol.22
, pp. 369-378
-
-
Kumar, A.1
Coleman, I.2
Morrissey, C.3
-
6
-
-
84863723010
-
The mutational landscape of lethal castration-resistant prostate cancer
-
Grasso CS, Wu YM, Robinson DR, et al. The mutational landscape of lethal castration-resistant prostate cancer. Nature. 2012; 487: 239-243
-
(2012)
Nature
, vol.487
, pp. 239-243
-
-
Grasso, C.S.1
Wu, Y.M.2
Robinson, D.R.3
-
7
-
-
84925231126
-
RNA biomarkers associated with metastatic progression in prostate cancer: A multi-institutional high-throughput analysis of SChLAP1
-
Prensner JR, Zhao S, Erho N, et al. RNA biomarkers associated with metastatic progression in prostate cancer: a multi-institutional high-throughput analysis of SChLAP1. Lancet Oncol. 2014; 15: 1469-1480
-
(2014)
Lancet Oncol
, vol.15
, pp. 1469-1480
-
-
Prensner, J.R.1
Zhao, S.2
Erho, N.3
-
8
-
-
84924655117
-
Identification of a candidate prognostic gene signature by transcriptome analysis of matched pre- and posttreatment prostatic biopsies from patients with advanced prostate cancer
-
Rajan P, Stockley J, Sudbery IM, et al. Identification of a candidate prognostic gene signature by transcriptome analysis of matched pre- and posttreatment prostatic biopsies from patients with advanced prostate cancer. BMC Cancer. 2014; 14: 977
-
(2014)
BMC Cancer
, vol.14
, pp. 977
-
-
Rajan, P.1
Stockley, J.2
Sudbery, I.M.3
-
9
-
-
84945395861
-
Transcriptome sequencing reveals PCAT5 as a novel ERG-regulated long noncoding RNA in prostate cancer
-
Ylipaa A, Kivinummi K, Kohvakka A, et al. Transcriptome sequencing reveals PCAT5 as a novel ERG-regulated long noncoding RNA in prostate cancer. Cancer Res. 2015; 75: 4026-4031
-
(2015)
Cancer Res
, vol.75
, pp. 4026-4031
-
-
Ylipaa, A.1
Kivinummi, K.2
Kohvakka, A.3
-
10
-
-
84907057471
-
AR-V7 and resistance to enzalutamide and abiraterone in prostate cancer
-
Antonarakis ES, Lu C, Wang H, et al. AR-V7 and resistance to enzalutamide and abiraterone in prostate cancer. N Engl J Med. 2014; 371: 1028-1038
-
(2014)
N Engl J Med
, vol.371
, pp. 1028-1038
-
-
Antonarakis, E.S.1
Lu, C.2
Wang, H.3
-
11
-
-
84876064523
-
Targeted next-generation sequencing of advanced prostate cancer identifies potential therapeutic targets and disease heterogeneity
-
Beltran H, Yelensky R, Frampton GM, et al. Targeted next-generation sequencing of advanced prostate cancer identifies potential therapeutic targets and disease heterogeneity. Eur Urol. 2013; 63: 920-926
-
(2013)
Eur Urol
, vol.63
, pp. 920-926
-
-
Beltran, H.1
Yelensky, R.2
Frampton, G.M.3
-
12
-
-
84983535287
-
Development and validation of a scalable next-generation sequencing system for assessing relevant somatic variants in solid tumors
-
Hovelson DH, McDaniel AS, Cani AK, et al. Development and validation of a scalable next-generation sequencing system for assessing relevant somatic variants in solid tumors. Neoplasia. 2015; 17: 385-399
-
(2015)
Neoplasia
, vol.17
, pp. 385-399
-
-
Hovelson, D.H.1
McDaniel, A.S.2
Cani, A.K.3
-
13
-
-
84982128149
-
A pilot study of clinical targeted next generation sequencing for prostate cancer: Consequences for treatment and genetic counseling
-
Cheng HH, Klemfuss N, Montgomery B, et al. A pilot study of clinical targeted next generation sequencing for prostate cancer: consequences for treatment and genetic counseling. Prostate. 2016
-
(2016)
Prostate
-
-
Cheng, H.H.1
Klemfuss, N.2
Montgomery, B.3
-
14
-
-
84941002648
-
The use of exome capture RNA-Seq for highly degraded RNA with application to clinical cancer sequencing
-
Cieslik M, Chugh R, Wu YM, et al. The use of exome capture RNA-Seq for highly degraded RNA with application to clinical cancer sequencing. Genome Res. 2015; 25: 1372-1381
-
(2015)
Genome Res
, vol.25
, pp. 1372-1381
-
-
Cieslik, M.1
Chugh, R.2
Wu, Y.M.3
-
15
-
-
84902148239
-
Whole-exome sequencing and clinical interpretation of formalin-fixed, paraffin-embedded tumor samples to guide precision cancer medicine
-
Van Allen EM, Wagle N, Stojanov P, et al. Whole-exome sequencing and clinical interpretation of formalin-fixed, paraffin-embedded tumor samples to guide precision cancer medicine. Nat Med. 2014; 20(6): 682-688
-
(2014)
Nat Med
, vol.20
, Issue.6
, pp. 682-688
-
-
Van Allen, E.M.1
Wagle, N.2
Stojanov, P.3
-
16
-
-
84873370892
-
New strategies in prostate cancer: Translating genomics into the clinic
-
Beltran H, Rubin MA. New strategies in prostate cancer: Translating genomics into the clinic. Clin Cancer Res. 2013; 19: 517-523
-
(2013)
Clin Cancer Res
, vol.19
, pp. 517-523
-
-
Beltran, H.1
Rubin, M.A.2
-
18
-
-
27344451557
-
Recurrent fusion of TMPRSS2 and ETS transcription factor genes in prostate cancer
-
Tomlins SA, Rhodes DR, Perner S, et al. Recurrent fusion of TMPRSS2 and ETS transcription factor genes in prostate cancer. Science. 2005; 310: 644-648
-
(2005)
Science
, vol.310
, pp. 644-648
-
-
Tomlins, S.A.1
Rhodes, D.R.2
Perner, S.3
-
19
-
-
44449139593
-
The role of SPINK1 in ETS rearrangement-negative prostate cancers
-
Tomlins SA, Rhodes DR, Yu J, et al. The role of SPINK1 in ETS rearrangement-negative prostate cancers. Cancer Cell. 2008; 13: 519-528
-
(2008)
Cancer Cell
, vol.13
, pp. 519-528
-
-
Tomlins, S.A.1
Rhodes, D.R.2
Yu, J.3
-
20
-
-
84933510527
-
Androgen receptor gene aberrations in circulating cell-free DNA: Biomarkers of therapeutic resistance in castrationresistant prostate cancer
-
AzadAA, Volik SV, WyattAW, et al. Androgen receptor gene aberrations in circulating cell-free DNA: biomarkers of therapeutic resistance in castrationresistant prostate cancer. Clin Cancer Res. 2015; 21: 2315-2324
-
(2015)
Clin Cancer Res
, vol.21
, pp. 2315-2324
-
-
Azad, A.A.1
Volik, S.V.2
Wyatt, A.W.3
-
21
-
-
84907285681
-
Tumor clone dynamics in lethal prostate cancer
-
254ra125
-
Carreira S, Romanel A, Goodall J, et al. Tumor clone dynamics in lethal prostate cancer. Sci Transl Med. 2014; 6: 254ra125
-
(2014)
Sci Transl Med
, vol.6
-
-
Carreira, S.1
Romanel, A.2
Goodall, J.3
-
22
-
-
85013175347
-
Genomic alterations in cell-free DNA and enzalutamide resistance in castration-resistant prostate cancer
-
published online ahead of print May 5 2016]
-
Wyatt AW, Azad AA, Volik SV, et al. Genomic alterations in cell-free DNA and enzalutamide resistance in castration-resistant prostate cancer [published online ahead of print May 5, 2016]. In: JAMA Oncol. 2016
-
(2016)
JAMA Oncol
-
-
Wyatt, A.W.1
Azad, A.A.2
Volik, S.V.3
-
23
-
-
84956577962
-
Functional analysis of androgen receptor mutations that confer anti-Androgen resistance identified in circulating cell-free DNA from prostate cancer patients
-
Lallous N, Volik SV, Awrey S, et al. Functional analysis of androgen receptor mutations that confer anti-Androgen resistance identified in circulating cell-free DNA from prostate cancer patients. Genome Biol. 2016; 17: 10
-
(2016)
Genome Biol
, vol.17
, pp. 10
-
-
Lallous, N.1
Volik, S.V.2
Awrey, S.3
-
24
-
-
84975744385
-
Whole-genome plasma sequencing reveals focal amplifications as a driving force in metastatic prostate cancer
-
Ulz P, Belic J, Graf R, et al. Whole-genome plasma sequencing reveals focal amplifications as a driving force in metastatic prostate cancer. Nat Commun. 2016; 7: 12008
-
(2016)
Nat Commun
, vol.7
, pp. 12008
-
-
Ulz, P.1
Belic, J.2
Graf, R.3
-
25
-
-
84900333051
-
Whole-exome sequencing of circulating tumor cells provides a windowinto metastatic prostate cancer
-
Lohr JG, Adalsteinsson VA, Cibulskis K, et al. Whole-exome sequencing of circulating tumor cells provides a windowinto metastatic prostate cancer. Nat Biotechnol. 2014; 32: 479-484
-
(2014)
Nat Biotechnol
, vol.32
, pp. 479-484
-
-
Lohr, J.G.1
Adalsteinsson, V.A.2
Cibulskis, K.3
-
26
-
-
84942904757
-
RNA-Seq of single prostate CTCs implicates noncanonical Wnt signaling in antiandrogen resistance
-
Miyamoto DT, Zheng Y, Wittner BS, et al. RNA-Seq of single prostate CTCs implicates noncanonical Wnt signaling in antiandrogen resistance. Science. 2015; 349: 1351-1356
-
(2015)
Science
, vol.349
, pp. 1351-1356
-
-
Miyamoto, D.T.1
Zheng, Y.2
Wittner, B.S.3
-
27
-
-
84887429673
-
Tracking the clonal origin of lethal prostate cancer
-
Haffner MC, Mosbruger T, Esopi DM, et al. Tracking the clonal origin of lethal prostate cancer. J Clin Invest. 2013; 123: 4918-4922
-
(2013)
J Clin Invest
, vol.123
, pp. 4918-4922
-
-
Haffner, M.C.1
Mosbruger, T.2
Esopi, D.M.3
-
28
-
-
0036321565
-
Morphologic and clinical significance of multifocal prostate cancers in radical prostatectomy specimens
-
Wise AM, Stamey TA, McNeal JE, et al. Morphologic and clinical significance of multifocal prostate cancers in radical prostatectomy specimens. Urology. 2002; 60: 264-269
-
(2002)
Urology
, vol.60
, pp. 264-269
-
-
Wise, A.M.1
Stamey, T.A.2
McNeal, J.E.3
-
29
-
-
84933277410
-
Spatial genomic heterogeneity within localized, multifocal prostate cancer
-
Boutros PC, Fraser M, Harding NJ, et al. Spatial genomic heterogeneity within localized, multifocal prostate cancer. Nat Genet. 2015; 47: 736-745
-
(2015)
Nat Genet
, vol.47
, pp. 736-745
-
-
Boutros, P.C.1
Fraser, M.2
Harding, N.J.3
-
30
-
-
84930195799
-
Analysis of the genetic phylogeny of multifocal prostate cancer identifies multiple independent clonal expansions in neoplastic and morphologically normal prostate tissue
-
Cooper CS, Eeles R, Wedge DC, et al. Analysis of the genetic phylogeny of multifocal prostate cancer identifies multiple independent clonal expansions in neoplastic and morphologically normal prostate tissue. Nat Genet. 2015; 47: 367-372
-
(2015)
Nat Genet
, vol.47
, pp. 367-372
-
-
Cooper, C.S.1
Eeles, R.2
Wedge, D.C.3
-
31
-
-
67349257845
-
Copy number analysis indicates monoclonal origin of lethal metastatic prostate cancer
-
LiuW, Laitinen S, Khan S, et al. Copy number analysis indicates monoclonal origin of lethal metastatic prostate cancer. Nat Med. 2009; 15: 559-565
-
(2009)
Nat Med
, vol.15
, pp. 559-565
-
-
LiuW Laitinen, S.1
Khan, S.2
-
32
-
-
84926330368
-
Tracking the origins and drivers of subclonal metastatic expansion in prostate cancer
-
HongMK, Macintyre G, Wedge DC, et al. Tracking the origins and drivers of subclonal metastatic expansion in prostate cancer. Nat Commun. 2015; 6: 6605
-
(2015)
Nat Commun
, vol.6
, pp. 6605
-
-
Hong, M.K.1
MacIntyre, G.2
Wedge, D.C.3
-
33
-
-
84957840165
-
Which, when and why. Rational use of tissue-based molecular testing in localized prostate cancer
-
Ross AE, D'Amico AV, Freedland SJ. Which, when and why?. Rational use of tissue-based molecular testing in localized prostate cancer. Prostate Cancer Prostatic Dis. 2016; 19: 1-6
-
(2016)
Prostate Cancer Prostatic Dis
, vol.19
, pp. 1-6
-
-
Ross, A.E.1
D'Amico, A.V.2
Freedland, S.J.3
-
34
-
-
0037130887
-
Breast Cancer Linkage Consortium. Cancer incidence in BRCA1 mutation carriers
-
Thompson D, Easton DF. Breast Cancer Linkage Consortium. Cancer incidence in BRCA1 mutation carriers. J Natl Cancer Inst. 2002; 94: 1358-1365
-
(2002)
J Natl Cancer Inst
, vol.94
, pp. 1358-1365
-
-
Thompson, D.1
Easton, D.F.2
-
35
-
-
1442307845
-
Cancer risks for male carriers of germline mutations in BRCA1 or BRCA2: A review of the literature
-
Liede A, Karlan BY, Narod SA. Cancer risks for male carriers of germline mutations in BRCA1 or BRCA2: a review of the literature. J Clin Oncol. 2004; 22(4): 735-742
-
(2004)
J Clin Oncol
, vol.22
, Issue.4
, pp. 735-742
-
-
Liede, A.1
Karlan, B.Y.2
Narod, S.A.3
-
36
-
-
85101730023
-
Mutations in BRCA1 and BRCA2 and predisposition to prostate cancer
-
author reply 80
-
TischkowitzM, Eeles R.Mutations in BRCA1 and BRCA2 and predisposition to prostate cancer. Lancet. 2003; 362: 80; author reply 80
-
(2003)
Lancet
, vol.362
, pp. 80
-
-
Tischkowitz, M.1
Eeles, R.2
-
37
-
-
54049130531
-
The role of the BRCA2 gene in susceptibility to prostate cancer revisited
-
Ostrander EA, Udler MS. The role of the BRCA2 gene in susceptibility to prostate cancer revisited. Cancer Epidemiol Biomarkers Prev. 2008; 17: 1843-1848
-
(2008)
Cancer Epidemiol Biomarkers Prev
, vol.17
, pp. 1843-1848
-
-
Ostrander, E.A.1
Udler, M.S.2
-
39
-
-
84856176782
-
Germline mutations in HOXB13 and prostate-cancer risk
-
Ewing CM, Ray AM, Lange EM, et al. Germline mutations in HOXB13 and prostate-cancer risk. N Engl JMed. 2012; 366: 141-149
-
(2012)
N Engl JMed
, vol.366
, pp. 141-149
-
-
Ewing, C.M.1
Ray, A.M.2
Lange, E.M.3
-
40
-
-
84860168795
-
Molecular characterization of neuroendocrine prostate cancer and identification of new drug targets
-
Beltran H, Rickman DS, Park K, et al.Molecular characterization of neuroendocrine prostate cancer and identification of new drug targets. Cancer Discov. 2011; 1: 487-495
-
(2011)
Cancer Discov
, vol.1
, pp. 487-495
-
-
Beltran, H.1
Rickman, D.S.2
Park, K.3
-
41
-
-
84900836746
-
Proposed morphologic classification of prostate cancer with neuroendocrine differentiation
-
Epstein JI, AminMB, Beltran H, et al. Proposed morphologic classification of prostate cancer with neuroendocrine differentiation. Am J Surg Pathol. 2014; 38: 756-767
-
(2014)
Am J Surg Pathol
, vol.38
, pp. 756-767
-
-
Epstein, J.I.1
Amin, M.B.2
Beltran, H.3
-
43
-
-
84942880558
-
Comprehensive serial molecular profiling of an N of 1" exceptional non-responder with metastatic prostate cancer progressing to small cell carcinoma on treatment
-
Kadakia KC, Tomlins SA, Sanghvi SK, et al. Comprehensive serial molecular profiling of an "N of 1" exceptional non-responder with metastatic prostate cancer progressing to small cell carcinoma on treatment. J Hematol Oncol. 2015; 8: 109
-
(2015)
J Hematol Oncol
, vol.8
, pp. 109
-
-
Kadakia, K.C.1
Tomlins, S.A.2
Sanghvi, S.K.3
-
44
-
-
84938054007
-
Integrative molecular profiling of routine clinical prostate cancer specimens
-
Grasso CS, Cani AK, Hovelson DH, et al. Integrative molecular profiling of routine clinical prostate cancer specimens. Ann Oncol. 2015; 26(6): 1110-1118
-
(2015)
Ann Oncol
, vol.26
, Issue.6
, pp. 1110-1118
-
-
Grasso, C.S.1
Cani, A.K.2
Hovelson, D.H.3
-
45
-
-
84900463472
-
Neuroendocrine prostate cancer: Subtypes, biology, and clinical outcomes
-
Aggarwal R, Zhang T, Small EJ, et al. Neuroendocrine prostate cancer: subtypes, biology, and clinical outcomes. J Natl Compr Cancer Netw. 2014; 12: 719-726
-
(2014)
J Natl Compr Cancer Netw
, vol.12
, pp. 719-726
-
-
Aggarwal, R.1
Zhang, T.2
Small, E.J.3
-
46
-
-
84879853237
-
Platinum-based chemotherapy for variant castrate-resistant prostate cancer
-
Aparicio AM, Harzstark A, Corn PG, et al. Platinum-based chemotherapy for variant castrate-resistant prostate cancer. Clin Cancer Res. 2013
-
(2013)
Clin Cancer Res
-
-
Aparicio, A.M.1
Harzstark, A.2
Corn, P.G.3
-
47
-
-
84945470634
-
Molecular landscape of prostate cancer: Implications for current clinical trials
-
Khemlina G, Ikeda S, Kurzrock R. Molecular landscape of prostate cancer: implications for current clinical trials. Cancer Treat Rev. 2015; 41: 761-766
-
(2015)
Cancer Treat Rev
, vol.41
, pp. 761-766
-
-
Khemlina, G.1
Ikeda, S.2
Kurzrock, R.3
-
48
-
-
84921367731
-
Synthetic lethality and cancer therapy: Lessons learned from the development of PARP inhibitors
-
Lord CJ, Tutt AN, Ashworth A. Synthetic lethality and cancer therapy: lessons learned from the development of PARP inhibitors. Annu Rev Med. 2015; 66: 455-470
-
(2015)
Annu Rev Med
, vol.66
, pp. 455-470
-
-
Lord, C.J.1
Tutt, A.N.2
Ashworth, A.3
-
49
-
-
84946019429
-
DNA-repair defects and olaparib in metastatic prostate cancer
-
Mateo J, Carreira S, Sandhu S, et al. DNA-repair defects and olaparib in metastatic prostate cancer. N Engl JMed. 2015; 373: 1697-1708
-
(2015)
N Engl JMed
, vol.373
, pp. 1697-1708
-
-
Mateo, J.1
Carreira, S.2
Sandhu, S.3
-
50
-
-
84973100750
-
Translational and clinical implications of the genetic landscape of prostate cancer
-
Spratt DE, Zumsteg ZS, Feng FY, et al. Translational and clinical implications of the genetic landscape of prostate cancer. In: Nat Rev Clin Oncol. 2016
-
(2016)
Nat Rev Clin Oncol
-
-
De, S.1
Zumsteg, Z.S.2
Feng, F.Y.3
-
51
-
-
84859154379
-
Beyond PSA: The next generation of prostate cancer biomarkers
-
Prensner JR, RubinMA, Wei JT, et al. Beyond PSA: The next generation of prostate cancer biomarkers. Sci Transl Med. 2012; 4: 127rv123
-
(2012)
Sci Transl Med
, vol.4
, pp. 127rv123
-
-
Prensner, J.R.1
Rubin, M.A.2
Wei, J.T.3
-
52
-
-
84887122461
-
The long noncoding RNA SChLAP1 promotes aggressive prostate cancer and antagonizes the SWI/SNF complex
-
Prensner JR, Iyer MK, Sahu A, et al. The long noncoding RNA SChLAP1 promotes aggressive prostate cancer and antagonizes the SWI/SNF complex. Nat Genet. 2013; 45(11): 1392-1398
-
(2013)
Nat Genet
, vol.45
, Issue.11
, pp. 1392-1398
-
-
Prensner, J.R.1
Iyer, M.K.2
Sahu, A.3
-
53
-
-
84904159704
-
The link between androgen receptor splice variants and castration-resistant prostate cancer
-
Sprenger CC, Plymate R. The link between androgen receptor splice variants and castration-resistant prostate cancer. Horm Cancer. 2014; 5: 207-217
-
(2014)
Horm Cancer
, vol.5
, pp. 207-217
-
-
Sprenger, C.C.1
Plymate, R.2
-
54
-
-
84900371086
-
Prostate cancer epigenetic biomarkers: Nextgeneration technologies
-
Valdes-Mora F, Clark SJ. Prostate cancer epigenetic biomarkers: nextgeneration technologies. Oncogene. 2015; 34: 1609-1618
-
(2015)
Oncogene
, vol.34
, pp. 1609-1618
-
-
Valdes-Mora, F.1
Clark, S.J.2
-
55
-
-
84871052080
-
EZH2 oncogenic activity in castrationresistant prostate cancer cells is polycomb-independent
-
Xu K, Wu ZJ, Groner AC, et al. EZH2 oncogenic activity in castrationresistant prostate cancer cells is polycomb-independent. Science. 2012; 338: 1465-1469.
-
(2012)
Science
, vol.338
, pp. 1465-1469
-
-
Xu, K.1
Wu, Z.J.2
Groner, A.C.3
|