-
1
-
-
0038150180
-
Endothelial dysfunction and the clinical application
-
Skultetyova, D., Filipova, S., Riecansky, I. and Mistrik, G. (2003) Endothelial dysfunction and the clinical application. Bratisl. Lek. Listy. 104, 40-41.
-
(2003)
Bratisl. Lek. Listy
, vol.104
, pp. 40-41
-
-
Skultetyova, D.1
Filipova, S.2
Riecansky, I.3
Mistrik, G.4
-
2
-
-
0036774737
-
Cyclooxygenase-2 and atherosclerosis
-
Linton, M.F., Fazio, S. (2002) Cyclooxygenase-2 and atherosclerosis. Curr. Opin. Lipidol. 13, 497-504.
-
(2002)
Curr. Opin. Lipidol
, vol.13
, pp. 497-504
-
-
Linton, M.F.1
Fazio, S.2
-
3
-
-
0034702914
-
Cyclooxygenase-1 and -2-dependent prostacyclin formation in patients with atherosclerosis
-
Belton, O., Byrne, D., Kearney, D., Leahy, A. and Fitzgerald, D. (2000) Cyclooxygenase-1 and -2-dependent prostacyclin formation in patients with atherosclerosis. Circulation 102, 840-845.
-
(2000)
Circulation
, vol.102
, pp. 840-845
-
-
Belton, O.1
Byrne, D.2
Kearney, D.3
Leahy, A.4
Fitzgerald, D.5
-
4
-
-
0032833967
-
Augmented expression of cyclooxygenase-2 in human atherosclerotic lesions
-
Schonbeck, U., Sukhova, G.K., Graber, P., Coulter, S. and Libby, P. (1999) Augmented expression of cyclooxygenase-2 in human atherosclerotic lesions. Am. J. Pathol. 155, 1281-1291.
-
(1999)
Am. J. Pathol
, vol.155
, pp. 1281-1291
-
-
Schonbeck, U.1
Sukhova, G.K.2
Graber, P.3
Coulter, S.4
Libby, P.5
-
5
-
-
0033015661
-
Cyclooxygenase-2 is widely expressed in atherosclerotic lesions affecting native and transplanted human coronary arteries and colocalizes with inducible nitric oxide synthase and nitrotyrosine particularly in macrophages. Arterioscler
-
Baker, C.S., Hall, R.J., Evans, T.J., Pomerance, A., Maclouf, J., Creminon, C., Yacoub, M.H. and Polak, J.M. (1999) Cyclooxygenase-2 is widely expressed in atherosclerotic lesions affecting native and transplanted human coronary arteries and colocalizes with inducible nitric oxide synthase and nitrotyrosine particularly in macrophages. Arterioscler. Thromb. Vasc. Biol. 19, 646-655.
-
(1999)
Thromb. Vasc. Biol
, vol.19
, pp. 646-655
-
-
Baker, C.S.1
Hall, R.J.2
Evans, T.J.3
Pomerance, A.4
Maclouf, J.5
Creminon, C.6
Yacoub, M.H.7
Polak, J.M.8
-
6
-
-
0020586721
-
Analysis of prostacyclin and thromboxane biosynthesis in cardiovascular disease
-
Fitzgerald, G.A., Pedersen, A.K. and Patrono, C. (1983) Analysis of prostacyclin and thromboxane biosynthesis in cardiovascular disease. Circulation 67, 1174-1177.
-
(1983)
Circulation
, vol.67
, pp. 1174-1177
-
-
Fitzgerald, G.A.1
Pedersen, A.K.2
Patrono, C.3
-
7
-
-
0035214784
-
Cyclooxygenase-2 and atherosclerosis: Friend or foe? Nephrol
-
Massy, Z.A. and Swan, S.K. (2001) Cyclooxygenase-2 and atherosclerosis: friend or foe? Nephrol. Dial Transplant. 16, 2286-2289.
-
(2001)
Dial Transplant
, vol.16
, pp. 2286-2289
-
-
Massy, Z.A.1
Swan, S.K.2
-
8
-
-
0037134010
-
Biomedicine. Back to an aspirin a day?
-
Vane, J.R. (2002) Biomedicine. Back to an aspirin a day? Science 296, 474-475.
-
(2002)
Science
, vol.296
, pp. 474-475
-
-
Vane, J.R.1
-
9
-
-
0034707105
-
Comparison of upper gastrointestinal toxicity of rofecoxib and naproxen in patients with rheumatoid arthritis
-
Bombardier, C., Laine, L., Reicin, A., Shapiro, D., Burgos-Vargas, R., Davis, B., Day, R., Ferraz, M.B., Hawkey, C.J., Hochberg, M.C., Kvien, T.K., Schnitzer, T.J. and VIGOR Study Group. (2000) Comparison of upper gastrointestinal toxicity of rofecoxib and naproxen in patients with rheumatoid arthritis. N. Engl. J. Med. 343, 1520-1528.
-
(2000)
N. Engl. J. Med
, vol.343
, pp. 1520-1528
-
-
Bombardier, C.1
Laine, L.2
Reicin, A.3
Shapiro, D.4
Burgos-Vargas, R.5
Davis, B.6
Day, R.7
Ferraz, M.B.8
Hawkey, C.J.9
Hochberg, M.C.10
Kvien, T.K.11
Schnitzer, T.J.12
-
10
-
-
0035925909
-
NSAIDs and selective COX-2 inhibitors: Competition between gastroprotection and cardioprotection
-
Boers, M. (2001) NSAIDs and selective COX-2 inhibitors: competition between gastroprotection and cardioprotection. Lancet. 357, 1222-1223.
-
(2001)
Lancet
, vol.357
, pp. 1222-1223
-
-
Boers, M.1
-
11
-
-
0036019178
-
How to study the effects of platelet aggregation and thrombosis on coronary vasomotion and their clinical relevance
-
Golino, P., Crea, F. and Willerson, J.T. (2002) How to study the effects of platelet aggregation and thrombosis on coronary vasomotion and their clinical relevance. Ital. Heart J. 3, 220-225.
-
(2002)
Ital. Heart J
, vol.3
, pp. 220-225
-
-
Golino, P.1
Crea, F.2
Willerson, J.T.3
-
12
-
-
0021022903
-
Arachdonate metabolism in vascular disorders
-
Majerus, P.W. (1983) Arachdonate metabolism in vascular disorders. J. Clin. Invest. 72, 1521-1525.
-
(1983)
J. Clin. Invest
, vol.72
, pp. 1521-1525
-
-
Majerus, P.W.1
-
13
-
-
0021989951
-
Endothelial cell prostacyclin production induced by activated neutrophils
-
Miller, D.K., Sadowski, S., Soderman, D.D. and Kuehl, F.A.Jr. (1985) Endothelial cell prostacyclin production induced by activated neutrophils. J. Biol. Chem. 260, 1006-1014.
-
(1985)
J. Biol. Chem
, vol.260
, pp. 1006-1014
-
-
Miller, D.K.1
Sadowski, S.2
Soderman, D.D.3
Kuehl, F.A.4
-
14
-
-
0022559202
-
Prostaglandin biosynthesis and its compartmentation in vascular smooth muscle and endothelial cells
-
Smith, W.L. (1986) Prostaglandin biosynthesis and its compartmentation in vascular smooth muscle and endothelial cells. Annu. Rev. Physiol. 48, 251-262.
-
(1986)
Annu. Rev. Physiol
, vol.48
, pp. 251-262
-
-
Smith, W.L.1
-
15
-
-
0022555865
-
Arachidonic acid metabolism
-
Needleman, P., Turk, J., Jackschik, B.A., Morrison, A.R. and Lefkowith, J.B. (1986) Arachidonic acid metabolism. Annu. Rev. Biochem. 55, 69-102.
-
(1986)
Annu. Rev. Biochem
, vol.55
, pp. 69-102
-
-
Needleman, P.1
Turk, J.2
Jackschik, B.A.3
Morrison, A.R.4
Lefkowith, J.B.5
-
16
-
-
3242725680
-
-
Oates, J.A., ed, Raven Press, New York
-
Granstrom, E., Diczfalusy, U., Hamberg, M., Hansson, G., Malmsten, C. and Samuelson, B. (1982) Prostaglandins and the cardiovascular system (Oates, J.A., ed) pp. 15-58, Raven Press, New York.
-
(1982)
Prostaglandins and the cardiovascular system
, pp. 15-58
-
-
Granstrom, E.1
Diczfalusy, U.2
Hamberg, M.3
Hansson, G.4
Malmsten, C.5
Samuelson, B.6
-
17
-
-
0028009093
-
The X-ray crystal structure of the membrane protein prostaglandin H2 synthase-1
-
Picot, D., Loll, P.J. and Garavitok, R.M. (1994) The X-ray crystal structure of the membrane protein prostaglandin H2 synthase-1. Nature 367, 243-249.
-
(1994)
Nature
, vol.367
, pp. 243-249
-
-
Picot, D.1
Loll, P.J.2
Garavitok, R.M.3
-
18
-
-
0029911267
-
Flexibility of the NSAID binding site in the structure of human cyclooxygenase-2
-
Luong, C., Miller, A., Barnett, J., Chow, J., Ramesha, C. and Browner, M.F. (1996) Flexibility of the NSAID binding site in the structure of human cyclooxygenase-2. Nat. Struct. Biol. 3, 927-933.
-
(1996)
Nat. Struct. Biol
, vol.3
, pp. 927-933
-
-
Luong, C.1
Miller, A.2
Barnett, J.3
Chow, J.4
Ramesha, C.5
Browner, M.F.6
-
19
-
-
0026502760
-
Primary structure of human thromboxane synthase determined from the cDNA sequence
-
Ohashi, K., Ruan, K.-H., Kulmacz, R.J., Wu, K.K. and Wang, L.-H. (1992) Primary structure of human thromboxane synthase determined from the cDNA sequence. J. Biol. Chem. 267, 789-793.
-
(1992)
J. Biol. Chem
, vol.267
, pp. 789-793
-
-
Ohashi, K.1
Ruan, K.-H.2
Kulmacz, R.J.3
Wu, K.K.4
Wang, L.-H.5
-
20
-
-
0025986862
-
Molecular cloning of human platelet thromboxane A synthase
-
Yokoyama, C., Miyata, A., Ihara, H., Ullrich, V. and Tanabe, T. (1991) Molecular cloning of human platelet thromboxane A synthase. Biochem. Biophys. Res. Commun. 178, 1479-1484.
-
(1991)
Biochem. Biophys. Res. Commun
, vol.178
, pp. 1479-1484
-
-
Yokoyama, C.1
Miyata, A.2
Ihara, H.3
Ullrich, V.4
Tanabe, T.5
-
21
-
-
85108921327
-
-
Cloning, expression, and chromosomal mapping thromboxane synthase
-
Shen, R.-F., Back, S.J., Zhang, L., Chase, M.B., Tai, H.-H. and Purtell, D.C. (1982) Eighth Int. Conf. on prostaglandins and related compounds. Cloning, expression, and chromosomal mapping thromboxane synthase.
-
(1982)
Eighth Int. Conf. on prostaglandins and related compounds
-
-
Shen, R.-F.1
Back, S.J.2
Zhang, L.3
Chase, M.B.4
Tai, H.-H.5
Purtell, D.C.6
-
22
-
-
0022400306
-
Isolation and characterization of thromboxane synthase from human platelets as a cytochrome P450 enzyme
-
Haurand, M. and Ullrich, V. (1985) Isolation and characterization of thromboxane synthase from human platelets as a cytochrome P450 enzyme. J. Biol. Chem. 260, 15059-15067.
-
(1985)
J. Biol. Chem
, vol.260
, pp. 15059-15067
-
-
Haurand, M.1
Ullrich, V.2
-
23
-
-
0001089993
-
Prostacyclin and thromboxane synthase as P-450 enzymes
-
Ullrich, V. and Graf, H. (1984) Prostacyclin and thromboxane synthase as P-450 enzymes. Trends Pharmacol. Sci. 5, 352-355.
-
(1984)
Trends Pharmacol. Sci
, vol.5
, pp. 352-355
-
-
Ullrich, V.1
Graf, H.2
-
24
-
-
0027326717
-
Crystal structure of hemoprotein domain of P450BM-3, a prototype for microsomal P450‘s
-
Ravichandran, K. G., Boddupalli, S. S., Hasemann, C. A., Peterson, J. A., and Deisenhofer, J. (1993) Crystal structure of hemoprotein domain of P450BM-3, a prototype for microsomal P450‘s. Science 261, 731-736.
-
(1993)
Science
, vol.261
, pp. 731-736
-
-
Ravichandran, K.G.1
Boddupalli, S.S.2
Hasemann, C.A.3
Peterson, J.A.4
Deisenhofer, J.5
-
25
-
-
0028173595
-
Comparison of the construction of a 3-D model for human thromboxane synthase using P450cam and BM-3 as templates: Implications for the substrate binding pocket
-
Ruan, K.-H., Milfeld, K., Kulmacz, R.J. and Wu K.K. (1994) Comparison of the construction of a 3-D model for human thromboxane synthase using P450cam and BM-3 as templates: implications for the substrate binding pocket. Protein Eng. 7, 1345-1351.
-
(1994)
Protein Eng
, vol.7
, pp. 1345-1351
-
-
Ruan, K.-H.1
Milfeld, K.2
Kulmacz, R.J.3
Wu, K.K.4
-
26
-
-
0029664951
-
Identification of thromboxane A2 synthase active site residues by molecular modeling-guided site-directed mutagenesis
-
Wang, L.-H., Matijevic-Aleksic, N., Hsu, P.Y., Ruan, K.-H., Wu, K.K. and Kulmacz, R.J. (1996) Identification of thromboxane A2 synthase active site residues by molecular modeling-guided site-directed mutagenesis. J. Biol. Chem. 33, 19970-19975.
-
(1996)
J. Biol. Chem
, vol.33
, pp. 19970-19975
-
-
Wang, L.-H.1
Matijevic-Aleksic, N.2
Hsu, P.Y.3
Ruan, K.-H.4
Wu, K.K.5
Kulmacz, R.J.6
-
27
-
-
0024474144
-
Purification of the thromboxane A2/prostagiandin H2, receptor from human blood platelets
-
Ushikubi, F., Nakajima, M., Hirata, M., Okuma, M., Fujiwara, M. and Narumiya, S. (1989) Purification of the thromboxane A2/prostagiandin H2, receptor from human blood platelets. J. Biol. Chem. 264, 16496-16501.
-
(1989)
J. Biol. Chem
, vol.264
, pp. 16496-16501
-
-
Ushikubi, F.1
Nakajima, M.2
Hirata, M.3
Okuma, M.4
Fujiwara, M.5
Narumiya, S.6
-
28
-
-
0026072992
-
Cloning and expression of cDNA for a human thromboxane A2, receptor
-
Hirata, M., Hayashi, Y., Ushikubi, F., Yokata, Y., Kageyama, R., Nakanishi, S., and Narumiya, S. (1991) Cloning and expression of cDNA for a human thromboxane A2, receptor. Nature 349, 617-620.
-
(1991)
Nature
, vol.349
, pp. 617-620
-
-
Hirata, M.1
Hayashi, Y.2
Ushikubi, F.3
Yokata, Y.4
Kageyama, R.5
Nakanishi, S.6
Narumiya, S.7
-
29
-
-
0028215803
-
Cloning and expression of a cDNA for the human prostacyclin receptor
-
Katsuyama, M., Sugimoto, Y., Namba, T., Irie, A., Negishi, M., Narumiya, S. and Ichikawa, A. (1994) Cloning and expression of a cDNA for the human prostacyclin receptor. FEBS Lett. 344, 74-88.
-
(1994)
FEBS Lett
, vol.344
, pp. 74-88
-
-
Katsuyama, M.1
Sugimoto, Y.2
Namba, T.3
Irie, A.4
Negishi, M.5
Narumiya, S.6
Ichikawa, A.7
-
30
-
-
0028157978
-
Cloning and expression of a cDNA for tile human prostanoid FP receptor
-
Abrarnovitz, M., Boie, Y., Nguyen, T., Rushmore, T.H., Bayne, M.A., Metters, K.M., Slipetz, D.M. and Grygorczyk, R. (1994) Cloning and expression of a cDNA for tile human prostanoid FP receptor. J. Biol. Chem. 269, 1356-1360.
-
(1994)
J. Biol. Chem
, vol.269
, pp. 1356-1360
-
-
Abrarnovitz, M.1
Boie, Y.2
Nguyen, T.3
Rushmore, T.H.4
Bayne, M.A.5
Metters, K.M.6
Slipetz, D.M.7
Grygorczyk, R.8
-
31
-
-
0027370888
-
Cloning and expression of CDNA for the human prostaglandin E receptor EP1 subtype
-
Funk, C.D., Furci, L., FitzGerald, G.A., Grygorczyk, R., Rochette, C., Bayne, M.A., Abramovitz, M., Adam, M. and Metters, K.M. (1993) Cloning and expression of CDNA for the human prostaglandin E receptor EP1 subtype. J. Biol. Chem. 268, 26767-26772.
-
(1993)
J. Biol. Chem
, vol.268
, pp. 26767-26772
-
-
Funk, C.D.1
Furci, L.2
FitzGerald, G.A.3
Grygorczyk, R.4
Rochette, C.5
Bayne, M.A.6
Abramovitz, M.7
Adam, M.8
Metters, K.M.9
-
32
-
-
0027485123
-
Cloning and expression of the EP2 subtype of human receptors for prostaglandin E2. Biochem
-
An, S., Yang, J., Xia, M. and Goetzl, E.J. (1993) Cloning and expression of the EP2 subtype of human receptors for prostaglandin E2. Biochem. Biophys. Res. Commun. 197, 263-270.
-
(1993)
Biophys. Res. Commun
, vol.197
, pp. 263-270
-
-
An, S.1
Yang, J.2
Xia, M.3
Goetzl, E.J.4
-
33
-
-
0028233402
-
Alternative splicing produces a divergent cytoplasmic tail in the human endothelial thromboxane A2, receptor
-
Bastien, L., Sawyer, N., Grygorczyk, R., Metters, M. and Adam, M. (1994) Alternative splicing produces a divergent cytoplasmic tail in the human endothelial thromboxane A2, receptor. J. Biol. Chem. 269, 11873-11877.
-
(1994)
J. Biol. Chem
, vol.269
, pp. 11873-11877
-
-
Bastien, L.1
Sawyer, N.2
Grygorczyk, R.3
Metters, M.4
Adam, M.5
-
34
-
-
0027976571
-
Cloning and expression of three isoforms of the human EP3 prostanoid receptor
-
Adam, M., Boie, Y., Rushmore, T.H., Muller, G., Bastien, L., McKee, K.T., Metters, K. M. and Abramovitz, M. (1994) Cloning and expression of three isoforms of the human EP3 prostanoid receptor. FEBS Lett. 338, 170-174.
-
(1994)
FEBS Lett
, vol.338
, pp. 170-174
-
-
Adam, M.1
Boie, Y.2
Rushmore, T.H.3
Muller, G.4
Bastien, L.5
McKee, K.T.6
Metters, K.M.7
Abramovitz, M.8
-
35
-
-
0028356164
-
Molecular cloning and expression of human EP3 receptors: Evidence of three variants with differing carboxyl termini
-
Regan, J.W., Bailey, T.J., Donello, J.E., Pierce, K.L., Pepperi, D.J., Zhang, D., Kedzie, K.M., Fairbaim, C.D., Bogardus, A.M., Woodward, D.F. and Gil, D.W. (1994) Molecular cloning and expression of human EP3 receptors: evidence of three variants with differing carboxyl termini. Br. J. Pharmacol. 112, 377-385.
-
(1994)
Br. J. Pharmacol
, vol.112
, pp. 377-385
-
-
Regan, J.W.1
Bailey, T.J.2
Donello, J.E.3
Pierce, K.L.4
Pepperi, D.J.5
Zhang, D.6
Kedzie, K.M.7
Fairbaim, C.D.8
Bogardus, A.M.9
Woodward, D.F.10
Gil, D.W.11
-
36
-
-
0028196770
-
Cloning and expression of a prostaglandin E receptor EP3 subtype from human erythroleukaemia cells
-
Kunapuli, S.P., Mao, G.F., Bastepe, M., Liu-Chen, L.Y., Li, S., Cheung, P.P., DeRiel, J.K. and Ashby, B. (1994) Cloning and expression of a prostaglandin E receptor EP3 subtype from human erythroleukaemia cells. Biochem. J. 298, 263-267.
-
(1994)
Biochem. J.
, vol.298
, pp. 263-267
-
-
Kunapuli, S.P.1
Mao, G.F.2
Bastepe, M.3
Liu-Chen, L.Y.4
Li, S.5
Cheung, P.P.6
DeRiel, J.K.7
Ashby, B.8
-
37
-
-
0028359829
-
Cloning and expression of the EP3- subtype of human receptors for prostaglandin E2. Biochem
-
Yang, J., Xia, M., Goetzl, E. J. and An, S. (1994) Cloning and expression of the EP3- subtype of human receptors for prostaglandin E2. Biochem. Biophys. Res. Commun. 198, 999-1006.
-
(1994)
Biophys. Res. Commun
, vol.198
, pp. 999-1006
-
-
Yang, J.1
Xia, M.2
Goetzl, E.J.3
An, S.4
-
38
-
-
0036669383
-
Function of prostanoid receptors: Studies on knockout mice
-
Kobayashi T, Narumiya S. (2002) Function of prostanoid receptors: studies on knockout mice. Prostaglandins Other Lipid Mediat. 68-69, 557-573.
-
(2002)
Prostaglandins Other Lipid Mediat
, vol.68-69
, pp. 557-573
-
-
Kobayashi, T.1
Narumiya, S.2
-
39
-
-
0034931501
-
Genetic and pharmacological analysis of prostanoid receptor function
-
Narumiya, S. and FitzGerald, G.A. (2001) Genetic and pharmacological analysis of prostanoid receptor function. J. Clin. Invest. 108, 25-30.
-
(2001)
J. Clin. Invest
, vol.108
, pp. 25-30
-
-
Narumiya, S.1
FitzGerald, G.A.2
-
40
-
-
0034237679
-
Distribution and function of prostanoid receptors: Studies from knockout mice
-
Sugimoto, Y., Narumiya, S. and Ichikawa A. (2000) Distribution and function of prostanoid receptors: studies from knockout mice. Prog. Lipid Res. 39, 289-314.
-
(2000)
Prog. Lipid Res
, vol.39
, pp. 289-314
-
-
Sugimoto, Y.1
Narumiya, S.2
Ichikawa, A.3
-
41
-
-
0032407666
-
Coagulation defects and altered hemodynamic responses in mice lacking receptors for thromboxane A2
-
Thomas, D.W., Mannon, R.B., Mannon, P.J., Latour, A., Oliver, J.A., Hoffman, M., Smithies, O., Koller, B.H. and Coffman, T.M. (1998) Coagulation defects and altered hemodynamic responses in mice lacking receptors for thromboxane A2. J. Clin. Invest. 102, 1994-2001.
-
(1998)
J. Clin. Invest
, vol.102
, pp. 1994-2001
-
-
Thomas, D.W.1
Mannon, R.B.2
Mannon, P.J.3
Latour, A.4
Oliver, J.A.5
Hoffman, M.6
Smithies, O.7
Koller, B.H.8
Coffman, T.M.9
-
42
-
-
0028845788
-
Molecular mechanisms of diverse actions of prostanoid receptors. Biochim
-
Negishi, M., Sugimoto, Y. and Ichikawa, A. (1995) Molecular mechanisms of diverse actions of prostanoid receptors. Biochim. Biophys. Acta 1259, 109-120.
-
(1995)
Biophys. Acta
, vol.1259
, pp. 109-120
-
-
Negishi, M.1
Sugimoto, Y.2
Ichikawa, A.3
-
43
-
-
0027436309
-
Point mutation in the seventh hydrophobic domain of the human thromboxane A2 receptor allows discrimination between agonist and antagonist binding sites
-
Funk, C.D., Furci, L., Moran, N., and Fitzgerald, G.A. (1993) Point mutation in the seventh hydrophobic domain of the human thromboxane A2 receptor allows discrimination between agonist and antagonist binding sites. Mol. Pharmacol. 44, 934-939.
-
(1993)
Mol. Pharmacol
, vol.44
, pp. 934-939
-
-
Funk, C.D.1
Furci, L.2
Moran, N.3
Fitzgerald, G.A.4
-
44
-
-
0027463272
-
Modeling of human thromboxane A2 receptor and analysis of the receptor-ligand interaction
-
Yamamoto, Y., Kamiya, K. and Terao, S. (1993) Modeling of human thromboxane A2 receptor and analysis of the receptor-ligand interaction. J. Med. Chem. 36, 820-825.
-
(1993)
J. Med. Chem
, vol.36
, pp. 820-825
-
-
Yamamoto, Y.1
Kamiya, K.2
Terao, S.3
-
45
-
-
0030269974
-
Site-directed mutagenesis of cysteinyl and serine residues of human thromboxane A2 receptor in insect cells
-
Chiang, N., Kan, W.M. and Tai, H.H. (1996) Site-directed mutagenesis of cysteinyl and serine residues of human thromboxane A2 receptor in insect cells. Arch. Biochem. Biophys. 334, 9-17.
-
(1996)
Arch. Biochem. Biophys
, vol.334
, pp. 9-17
-
-
Chiang, N.1
Kan, W.M.2
Tai, H.H.3
-
46
-
-
0031007380
-
The second extracellular loop of the prostaglandin EP3 receptor is an essential determinant of ligand selectivity
-
Breyer, R.M and Audoly, L. (1997) The second extracellular loop of the prostaglandin EP3 receptor is an essential determinant of ligand selectivity. J. Biol. Chem. 272, 13475-13478.
-
(1997)
J. Biol. Chem
, vol.272
, pp. 13475-13478
-
-
Breyer, R.M.1
Audoly, L.2
-
47
-
-
0037053404
-
Mapping of a ligand-binding site for the human thromboxane A2 receptor protein
-
Turek, J.W., Halmos, T., Sullivan, N.L., Antonakis, K. and Le Breton, G.C. (2002) Mapping of a ligand-binding site for the human thromboxane A2 receptor protein. J. Biol. Chem. 277, 16791-16797.
-
(2002)
J. Biol. Chem
, vol.277
, pp. 16791-16797
-
-
Turek, J.W.1
Halmos, T.2
Sullivan, N.L.3
Antonakis, K.4
Le Breton, G.C.5
-
48
-
-
0038175397
-
Identification of residues important for ligand binding of thromboxane A2 receptor in the second extracellular loop using the NMR experiment-guided mutagenesis approach
-
So, S.-P., Wu, J., Huang, G., Huang, A., Li, D. and Ruan, K.-H. (2003) Identification of residues important for ligand binding of thromboxane A2 receptor in the second extracellular loop using the NMR experiment-guided mutagenesis approach. J. Biol. Chem. 278, 10922-10927.
-
(2003)
J. Biol. Chem
, vol.278
, pp. 10922-10927
-
-
So, S.-P.1
Wu, J.2
Huang, G.3
Huang, A.4
Li, D.5
Ruan, K.-H.6
-
49
-
-
0025292355
-
Model for the structure of bacteriorhodopsin based on high-resolution electron cryo-microscopy
-
Henderson, R., Baldwin, J.M., Ceska, T.A., Zemlin, F., Beckmann, E. and Downing, K.H. (1990) Model for the structure of bacteriorhodopsin based on high-resolution electron cryo-microscopy. J. Mol. Biol. 213, 899-929.
-
(1990)
J. Mol. Biol
, vol.213
, pp. 899-929
-
-
Henderson, R.1
Baldwin, J.M.2
Ceska, T.A.3
Zemlin, F.4
Beckmann, E.5
Downing, K.H.6
-
50
-
-
0029903197
-
Electron-crystallographic refinement of the structure of bacteriorhodopsin
-
Grigorieff, N., Ceska, T.A., Downing, K.H., Baldwin, J.M. and Henderson, R. (1996) Electron-crystallographic refinement of the structure of bacteriorhodopsin. J. Mol. Biol. 259, 393-421.
-
(1996)
J. Mol. Biol
, vol.259
, pp. 393-421
-
-
Grigorieff, N.1
Ceska, T.A.2
Downing, K.H.3
Baldwin, J.M.4
Henderson, R.5
-
51
-
-
0030864048
-
X-ray structure of bacteriorhodopsin at 2.5 angstroms from microcrystals grown in lipidic cubic phases
-
Pebay-Peyroula, E., Rummell, G., Rosenbusch, J.P. and Landau, E.M. (1997) X-ray structure of bacteriorhodopsin at 2.5 angstroms from microcrystals grown in lipidic cubic phases. Science 277, 1676-1681.
-
(1997)
Science
, vol.277
, pp. 1676-1681
-
-
Pebay-Peyroula, E.1
Rummell, G.2
Rosenbusch, J.P.3
Landau, E.M.4
-
52
-
-
0034604451
-
Crystal structure of rhodopsin: A G protein-coupled receptor
-
Palczewski, K., Kumasaka, T., Hori, T., Behnke, C.A., Motoshima, H., Fox, B.A., Le Trong, I., Teller, D.C., Okada, T., Stenkamp, R.E., Yamamoto, M. and Miyano, M. (2000) Crystal structure of rhodopsin: A G protein-coupled receptor. Science 289, 739-745.
-
(2000)
Science
, vol.289
, pp. 739-745
-
-
Palczewski, K.1
Kumasaka, T.2
Hori, T.3
Behnke, C.A.4
Motoshima, H.5
Fox, B.A.6
Le Trong, I.7
Teller, D.C.8
Okada, T.9
Stenkamp, R.E.10
Yamamoto, M.11
Miyano, M.12
-
53
-
-
0035830401
-
Solution structure of the second extracellular loop of human thromboxane A2 receptor
-
Ruan, K.-H., So, S.-P., Wu, J., Li, D., Huang, A. and Kung, J. (2001) Solution structure of the second extracellular loop of human thromboxane A2 receptor. Biochemistry 40, 275-280.
-
(2001)
Biochemistry
, vol.40
, pp. 275-280
-
-
Ruan, K.-H.1
So, S.-P.2
Wu, J.3
Li, D.4
Huang, A.5
Kung, J.6
-
54
-
-
0037763754
-
Solution structure of the third extracellular loop of human thromboxane A2 receptor. Arch. Biochem
-
Wu, J., So, S.-P. and Ruan, K.-H. (2003) Solution structure of the third extracellular loop of human thromboxane A2 receptor. Arch. Biochem. Biophys. 414, 287-293.
-
(2003)
Biophys
, vol.414
, pp. 287-293
-
-
Wu, J.1
So, S.-P.2
Ruan, K.-H.3
-
55
-
-
0025253345
-
Cyclic oxidation-reduction reactions regulate thromboxane A2/prostaglandin H2 receptor number and affinity in human platelet membranes. J. Biol
-
Dorn, G.W.2nd (1990) Cyclic oxidation-reduction reactions regulate thromboxane A2/prostaglandin H2 receptor number and affinity in human platelet membranes. J. Biol. Chem. 265, 4240-4246.
-
(1990)
Chem
, vol.265
, pp. 4240-4246
-
-
Dorn, G.W.1
-
56
-
-
0029969368
-
Mutagenic analysis of platelet thromboxane receptor cysteines
-
D’Angelo, D.D., Eubank, J.J., Davis, M.G. and Dorn, G.W.2nd. (1996) Mutagenic analysis of platelet thromboxane receptor cysteines. J. Biol. Chem. 271, 6233-6240.
-
(1996)
J. Biol. Chem
, vol.271
, pp. 6233-6240
-
-
D’Angelo, D.D.1
Eubank, J.J.2
Davis, M.G.3
Dorn, G.W.4
-
57
-
-
0025879308
-
Differential effect of pH on thromboxane A2/prostaglandin H2 receptor agonist and antagonist binding in human platelets
-
Mayeux, P.R., Morinelli, T.A., Williams, T.C., Hazard, E.S., Mais, D.E., Oatis, J.E., Baron, D.A. and Halushka, P.V. (1991) Differential effect of pH on thromboxane A2/prostaglandin H2 receptor agonist and antagonist binding in human platelets. J. Biol. Chem. 266, 13752-13758.
-
(1991)
J. Biol. Chem
, vol.266
, pp. 13752-13758
-
-
Mayeux, P.R.1
Morinelli, T.A.2
Williams, T.C.3
Hazard, E.S.4
Mais, D.E.5
Oatis, J.E.6
Baron, D.A.7
Halushka, P.V.8
-
58
-
-
0030911357
-
Structural determinants for agonist binding affinity to thromboxane/prostaglandin endoperoxide (TP) receptors. Analysis of chimeric rat/human TP receptors
-
Dorn, G.W.2nd, Davis, M.G. and D’Angelo, D.D. (1997) Structural determinants for agonist binding affinity to thromboxane/prostaglandin endoperoxide (TP) receptors. Analysis of chimeric rat/human TP receptors. J. Biol. Chem. 272, 12399-12405.
-
(1997)
J. Biol. Chem
, vol.272
, pp. 12399-12405
-
-
Dorn, G.W.1
Davis, M.G.2
D’Angelo, D.D.3
-
59
-
-
0034121737
-
New trends in thromboxane and prostacyclin modulators
-
Dogne, J.M., de Leval, X., Delarge, J., David, J.L. and Masereel, B. (2000) New trends in thromboxane and prostacyclin modulators. Curr. Med. Chem. 7, 609-628.
-
(2000)
Curr. Med. Chem
, vol.7
, pp. 609-628
-
-
Dogne, J.M.1
de Leval, X.2
Delarge, J.3
David, J.L.4
Masereel, B.5
-
60
-
-
0038044803
-
Atherosclerosis:Current concepts of pathophysiology and pharmacological intervention based on trial outcomes
-
Von Baeyer, H., Hopfenmuller, W., Riedel, E. and Affeld, K. (2003) Atherosclerosis:current concepts of pathophysiology and pharmacological intervention based on trial outcomes. Clin. Nephrol. 60 (Suppl 1), 31-48.
-
(2003)
Clin. Nephrol
, vol.60
, pp. 31-48
-
-
Von Baeyer, H.1
Hopfenmuller, W.2
Riedel, E.3
Affeld, K.4
-
61
-
-
0033524421
-
Systemic biosynthesis of prostacyclin by cyclooxygenase (COX)-2: The human pharmacology of a selective inhibitor of COX-2
-
McAdam, B.F., Catella-Lawson, F., Mardini, I.A., Kapoor, S., Lawson, J.A. and FitzGerald, G.A. (1999) Systemic biosynthesis of prostacyclin by cyclooxygenase (COX)-2: the human pharmacology of a selective inhibitor of COX-2. Proc. Natl. Acad. Sci. USA 96, 272-277.
-
(1999)
Proc. Natl. Acad. Sci. USA
, vol.96
, pp. 272-277
-
-
McAdam, B.F.1
Catella-Lawson, F.2
Mardini, I.A.3
Kapoor, S.4
Lawson, J.A.5
FitzGerald, G.A.6
-
62
-
-
0033740792
-
Sulindac inhibits neointimal formation after arterial injury in wild-type and apolipoprotein E-deficient mice
-
Reis, E.D., Roque, M., Dansky, H., Fallon, J.T., Badimon, J.J., Cordon-Cardo, C., Shiff, S.J. and Fisher, E.A. (2000) Sulindac inhibits neointimal formation after arterial injury in wild-type and apolipoprotein E-deficient mice. Proc. Natl. Acad. Sci. USA 97, 12764-12769.
-
(2000)
Proc. Natl. Acad. Sci. USA
, vol.97
, pp. 12764-12769
-
-
Reis, E.D.1
Roque, M.2
Dansky, H.3
Fallon, J.T.4
Badimon, J.J.5
Cordon-Cardo, C.6
Shiff, S.J.7
Fisher, E.A.8
-
63
-
-
0035853050
-
Acceleration of atherogenesis by COX-1-dependent prostanoid formation in low density lipoprotein receptor knockout mice
-
Pratico, D., Tillmann, C., Zhi-Bing, Z., Hongwei, L. and FitzGerald, G.A. (2001) Acceleration of atherogenesis by COX-1-dependent prostanoid formation in low density lipoprotein receptor knockout mice. Proc. Natl. Acad. Sci. USA 98, 3358-3363.
-
(2001)
Proc. Natl. Acad. Sci. USA
, vol.98
, pp. 3358-3363
-
-
Pratico, D.1
Tillmann, C.2
Zhi-Bing, Z.3
Hongwei, L.4
FitzGerald, G.A.5
-
64
-
-
17644434771
-
NO (nitric oxide) and its significance in regulation of vascular homeostasis
-
Kvasnicka, T., (2003) NO (nitric oxide) and its significance in regulation of vascular homeostasis. Vnitr. Lek. 49, 291-296.
-
(2003)
Vnitr. Lek
, vol.49
, pp. 291-296
-
-
Kvasnicka, T.1
-
65
-
-
0036902651
-
Prostacyclin is an autocrine regulator in the contraction of oviductal smooth muscle
-
Arbab, F., Goldsby, J., Matijevic-Aleksic, N., Huang, G., Ruan, K.H. and Huang, J.C. (2002) Prostacyclin is an autocrine regulator in the contraction of oviductal smooth muscle. Hum. Reprod. 17, 3053-3059.
-
(2002)
Hum. Reprod
, vol.17
, pp. 3053-3059
-
-
Arbab, F.1
Goldsby, J.2
Matijevic-Aleksic, N.3
Huang, G.4
Ruan, K.H.5
Huang, J.C.6
-
66
-
-
0036736835
-
Human fallopian tubes express prostacyclin (PGI) synthase and cyclooxygenases and synthesize abundant PGI
-
Huang, J.C., Arbab, F., Tumbusch, K.J., Goldsby, J.S., Matijevic-Aleksic, N. and Wu, K.K. (2002) Human fallopian tubes express prostacyclin (PGI) synthase and cyclooxygenases and synthesize abundant PGI. J. Clin. Endocrinol. Metab. 87, 4361-4368.
-
(2002)
J. Clin. Endocrinol. Metab
, vol.87
, pp. 4361-4368
-
-
Huang, J.C.1
Arbab, F.2
Tumbusch, K.J.3
Goldsby, J.S.4
Matijevic-Aleksic, N.5
Wu, K.K.6
-
67
-
-
0037443436
-
Regulation of cyclooxygenase-2 expression by iloprost in human vascular smooth muscle cells. Role of transcription factors CREB and ICER. Biochem
-
Debey, S., Meyer-Kirchrath, J. and Schror, K. (2003) Regulation of cyclooxygenase-2 expression by iloprost in human vascular smooth muscle cells. Role of transcription factors CREB and ICER. Biochem. Pharmacol. 65, 979-988.
-
(2003)
Pharmacol
, vol.65
, pp. 979-988
-
-
Debey, S.1
Meyer-Kirchrath, J.2
Schror, K.3
-
68
-
-
0037115766
-
Solution structure and topology of the N-terminal membrane anchor domain of a microsomal cytochrome P450: Prostaglandin I2 synthase
-
Ruan, K.-H., So, S.-P., Zheng, W., Wu, J., Li, D. and Kung, J. (2002) Solution structure and topology of the N-terminal membrane anchor domain of a microsomal cytochrome P450: prostaglandin I2 synthase. Biochem. J. 368, 1-7.
-
(2002)
Biochem. J.
, vol.368
, pp. 1-7
-
-
Ruan, K.-H.1
So, S.-P.2
Zheng, W.3
Wu, J.4
Li, D.5
Kung, J.6
-
69
-
-
0034661453
-
Topology of catalytic portion of prostaglandin I(2) synthase: Identification by molecular modeling-guided site-specific antibodies
-
Lin, Y.Z., Deng, H. and Ruan, K.-H. (2000) Topology of catalytic portion of prostaglandin I(2) synthase: identification by molecular modeling-guided site-specific antibodies. Arch. Biochem. Biophys. 379, 188-197.
-
(2000)
Arch. Biochem. Biophys
, vol.379
, pp. 188-197
-
-
Lin, Y.Z.1
Deng, H.2
Ruan, K.-H.3
-
70
-
-
0037086473
-
Substrate access channel topology in membrane-bound prostacyclin synthase
-
Deng, H., Huang, A., So, S.P., Lin, Y.Z. and Ruan, K.-H. (2002) Substrate access channel topology in membrane-bound prostacyclin synthase. Biochem. J. 362, 545-551.
-
(2002)
Biochem. J
, vol.362
, pp. 545-551
-
-
Deng, H.1
Huang, A.2
So, S.P.3
Lin, Y.Z.4
Ruan, K.-H.5
-
71
-
-
0028339975
-
Cloning and expression of a cDNA for the human prostanoid IP receptor
-
Boie, Y., Rushmore, T.H., Darmon-Goodwin, A., Grygorczyk, R., Slipetz, D.M., Metters, K.M. and Abramovitz, M.J. (1994) Cloning and expression of a cDNA for the human prostanoid IP receptor. J. Biol. Chem. 269, 12173-12178.
-
(1994)
J. Biol. Chem
, vol.269
, pp. 12173-12178
-
-
Boie, Y.1
Rushmore, T.H.2
Darmon-Goodwin, A.3
Grygorczyk, R.4
Slipetz, D.M.5
Metters, K.M.6
Abramovitz, M.J.7
-
72
-
-
0027948504
-
Molecular cloning of human prostacyclin receptor cDNA and its gene expression in the cardiovascular system
-
Nakagawa, O., Tanaka, I., Usui, T., Harada, M., Sasaki, Y., Itoh, H., Yoshimasa, T., Namba, T., Narumiya, S. and Nakao, K. (1994) Molecular cloning of human prostacyclin receptor cDNA and its gene expression in the cardiovascular system. Circulation 90, 1643-1647.
-
(1994)
Circulation
, vol.90
, pp. 1643-1647
-
-
Nakagawa, O.1
Tanaka, I.2
Usui, T.3
Harada, M.4
Sasaki, Y.5
Itoh, H.6
Yoshimasa, T.7
Namba, T.8
Narumiya, S.9
Nakao, K.10
-
73
-
-
0022434048
-
Defects in the prostaglandin system. II. Familial platelet-prostacyclin receptor defect (Wien-Hietzing defect)--pathogenetic significance for (early) development of atherosclerosis?
-
Kaliman, J., Sinzinger, H., Staudacher, M. and Mannheimer, E. (1985) Defects in the prostaglandin system. II. Familial platelet-prostacyclin receptor defect (Wien-Hietzing defect)--pathogenetic significance for (early) development of atherosclerosis? Wien Klin Wochenschr 97, 323-326.
-
(1985)
Wien Klin Wochenschr
, vol.97
, pp. 323-326
-
-
Kaliman, J.1
Sinzinger, H.2
Staudacher, M.3
Mannheimer, E.4
-
74
-
-
0033045715
-
A novel subtype of prostacyclin receptor in the central nervous system
-
Watanabe, Y., Matsumura, K., Takechi, H., Kato, K., Morii, H., Bjorkman, M., Langstrom, B., Noyori, R., Suzuki, M. and Watanabe, Y. (1999) A novel subtype of prostacyclin receptor in the central nervous system. J. Neurochem. 72, 2583-2592.
-
(1999)
J. Neurochem
, vol.72
, pp. 2583-2592
-
-
Watanabe, Y.1
Matsumura, K.2
Takechi, H.3
Kato, K.4
Morii, H.5
Bjorkman, M.6
Langstrom, B.7
Noyori, R.8
Suzuki, M.9
Watanabe, Y.10
-
75
-
-
0025132245
-
Activation of a member of the steroid hormone receptor superfamily by peroxisome proliferators
-
Issemann, I. and Green, S. (1990) Activation of a member of the steroid hormone receptor superfamily by peroxisome proliferators. Nature 347, 645-650.
-
(1990)
Nature
, vol.347
, pp. 645-650
-
-
Issemann, I.1
Green, S.2
-
76
-
-
0037192764
-
Peroxisome proliferator-activated receptor delta is up-regulated during vascular lesion formation and promotes post-confluent cell proliferation in vascular smooth muscle cells
-
Zhang, J., Fu, M., Zhu, X., Xiao, Y., Mou, Y., Zheng, H., Akinbami, M.A., Wang, Q. and Chen, Y.E. (2002) Peroxisome proliferator-activated receptor delta is up-regulated during vascular lesion formation and promotes post-confluent cell proliferation in vascular smooth muscle cells. J. Biol. Chem. 277, 11505-11512.
-
(2002)
J. Biol. Chem
, vol.277
, pp. 11505-11512
-
-
Zhang, J.1
Fu, M.2
Zhu, X.3
Xiao, Y.4
Mou, Y.5
Zheng, H.6
Akinbami, M.A.7
Wang, Q.8
Chen, Y.E.9
-
77
-
-
0142020927
-
Medicine. PPARs as therapeutic targets: Reverse cardiology?
-
Plutzky, J. (2003) Medicine. PPARs as therapeutic targets: reverse cardiology? Science 302, 406-407.
-
(2003)
Science
, vol.302
, pp. 406-407
-
-
Plutzky, J.1
-
78
-
-
0347334429
-
Obesity, adiponectin and vascular inflammatory disease
-
Ouchi, N., Kihara, S., Funahashi, T., Matsuzawa, Y. and Walsh, K. (2003) Obesity, adiponectin and vascular inflammatory disease. Curr. Opin. Lipidol. 14, 561-566.
-
(2003)
Curr. Opin. Lipidol
, vol.14
, pp. 561-566
-
-
Ouchi, N.1
Kihara, S.2
Funahashi, T.3
Matsuzawa, Y.4
Walsh, K.5
-
79
-
-
0348110529
-
Endothelial function, inflammation, and prognosis in cardiovascular disease
-
Gonzalez, M.A., and Selwyn, A.P. (2003) Endothelial function, inflammation, and prognosis in cardiovascular disease. Am. J. Med. 115 Suppl 8A, 99S-106S.
-
(2003)
Am. J. Med
, vol.115
, pp. 99S-106
-
-
Gonzalez, M.A.1
Selwyn, A.P.2
-
80
-
-
0036669567
-
Prostaglandin E synthase
-
Murakami, M., Nakatani, Y., Tanioka, T. and Kudo, I. (2002) Prostaglandin E synthase. Prostaglandins Other Lipid Mediat. 68-69, 383-399.
-
(2002)
Prostaglandins Other Lipid Mediat
, vol.68-69
, pp. 383-399
-
-
Murakami, M.1
Nakatani, Y.2
Tanioka, T.3
Kudo, I.4
-
81
-
-
0034693050
-
Molecular identification of cytosolic prostaglandin E2 synthase that is functionally coupled with cyclooxygenase-1 in immediate prostaglandin E2 biosynthesis
-
Tanioka, T., Nakatani, Y., Semmyo, N., Murakami, M. and Kudo, I. (2000) Molecular identification of cytosolic prostaglandin E2 synthase that is functionally coupled with cyclooxygenase-1 in immediate prostaglandin E2 biosynthesis. J. Biol. Chem. 275, 32775-32782.
-
(2000)
J. Biol. Chem
, vol.275
, pp. 32775-32782
-
-
Tanioka, T.1
Nakatani, Y.2
Semmyo, N.3
Murakami, M.4
Kudo, I.5
-
82
-
-
0141733073
-
Cellular prostaglandin E2 production by membrane-bound prostaglandin E synthase-2 via both cyclooxygenases-1 and -2
-
Murakami, M., Nakashima, K., Kamei, D., Masuda, S., Ishikawa, Y., Ishii, T., Ohmiya, Y., Watanabe, K. and Kudo, I. (2003) Cellular prostaglandin E2 production by membrane-bound prostaglandin E synthase-2 via both cyclooxygenases-1 and -2. J. Biol. Chem. 278, 37937-37947.
-
(2003)
J. Biol. Chem
, vol.278
, pp. 37937-37947
-
-
Murakami, M.1
Nakashima, K.2
Kamei, D.3
Masuda, S.4
Ishikawa, Y.5
Ishii, T.6
Ohmiya, Y.7
Watanabe, K.8
Kudo, I.9
-
83
-
-
0035928784
-
Overexpression of functionally coupled cyclooxygenase-2 and prostaglandin E synthase in symptomatic atherosclerotic plaques as a basis of prostaglandin E(2)- dependent plaque instability
-
Cipollone, F., Prontera, C., Pini, B., Marini, M., Fazia, M., De Cesare, D., Iezzi, A., Ucchino, S., Boccoli, G., Saba, V., Chiarelli, F., Cuccurullo, F., Mezzetti, A. (2001) Overexpression of functionally coupled cyclooxygenase-2 and prostaglandin E synthase in symptomatic atherosclerotic plaques as a basis of prostaglandin E(2)- dependent plaque instability. Circulation 104, 921-927.
-
(2001)
Circulation
, vol.104
, pp. 921-927
-
-
Cipollone, F.1
Prontera, C.2
Pini, B.3
Marini, M.4
Fazia, M.5
De Cesare, D.6
Iezzi, A.7
Ucchino, S.8
Boccoli, G.9
Saba, V.10
Chiarelli, F.11
Cuccurullo, F.12
Mezzetti, A.13
|