-
1
-
-
0025728865
-
Prostaglandin endoperoxide synthase: Structure and catalysis
-
Smith WL, Marnett LJ. Prostaglandin endoperoxide synthase: structure and catalysis. Biochim Biophys Acta 1991; 1083:1-17.
-
(1991)
Biochim Biophys Acta
, vol.1083
, pp. 1-17
-
-
Smith, W.L.1
Marnett, L.J.2
-
2
-
-
0031689543
-
Cyclooxygenase in biology and disease
-
DuBois RN, Abramson SB, Crofford L, et al. Cyclooxygenase in biology and disease. FASEB J 1998; 12:1063-1073.
-
(1998)
FASEB J
, vol.12
, pp. 1063-1073
-
-
DuBois, R.N.1
Abramson, S.B.2
Crofford, L.3
-
3
-
-
0023854087
-
Regulation of fibroblast cyclooxygenase synthesis by interleukin-1
-
Raz A, Wyche A, Siegel N, Needleman P. Regulation of fibroblast cyclooxygenase synthesis by interleukin-1. J Biol Chem 1988; 263:3022-3028.
-
(1988)
J Biol Chem
, vol.263
, pp. 3022-3028
-
-
Raz, A.1
Wyche, A.2
Siegel, N.3
Needleman, P.4
-
4
-
-
0030272216
-
In vivo and in vitro expression of a non-mammalian cyclooxygenase-1
-
Reed DW, Bradshaw WS, Xie W, Simmons DL. In vivo and in vitro expression of a non-mammalian cyclooxygenase-1. Prostaglandins 1996; 52:269-284.
-
(1996)
Prostaglandins
, vol.52
, pp. 269-284
-
-
Reed, D.W.1
Bradshaw, W.S.2
Xie, W.3
Simmons, D.L.4
-
5
-
-
0032516490
-
Cyclooxygenase-2 induction in congestive heart failure friend or foe?
-
Wu KK. Cyclooxygenase-2 induction in congestive heart failure friend or foe? Circulation 1998; 98:95-96.
-
(1998)
Circulation
, vol.98
, pp. 95-96
-
-
Wu, K.K.1
-
6
-
-
0028147767
-
Structure of the human cyclooxygenase-2 gene
-
Appleby SB, Ristimaki A, Nelson K, et al. Structure of the human cyclooxygenase-2 gene. Biochem J 1994; 302:723-737.
-
(1994)
Biochem J
, vol.302
, pp. 723-737
-
-
Appleby, S.B.1
Ristimaki, A.2
Nelson, K.3
-
7
-
-
0030871687
-
COX-1 and COX-2 tissue expression: Implications and predictions
-
Crofford LJ. COX-1 and COX-2 tissue expression: implications and predictions. J Rheumatol 1997; 24 (Suppl 49):15-19.
-
(1997)
J Rheumatol
, vol.24
, Issue.SUPPL. 49
, pp. 15-19
-
-
Crofford, L.J.1
-
8
-
-
0032833967
-
Augmented expression of cyclooxygenase-2 in human atherosclerotic lesions
-
Schonbeck U, Sukhova GK, Graber P, et al. Augmented expression of cyclooxygenase-2 in human atherosclerotic lesions. Am J Pathol 1999; 155:1281-1291.
-
(1999)
Am J Pathol
, vol.155
, pp. 1281-1291
-
-
Schonbeck, U.1
Sukhova, G.K.2
Graber, P.3
-
9
-
-
0033015661
-
Cyclooxygenase-2 is widely expressed in atherosclerotic lesions affecting native and transplanted human coronary arteries and colocalizes with inducible nitric oxide synthase and nitrotyrosine particularly in macrophages
-
Baker CS, Hall RJ, Evans TJ, et al. Cyclooxygenase-2 is widely expressed in atherosclerotic lesions affecting native and transplanted human coronary arteries and colocalizes with inducible nitric oxide synthase and nitrotyrosine particularly in macrophages. Arterioscler Thromb Vasc Biol 1999; 19:646-655.
-
(1999)
Arterioscler Thromb Vasc Biol
, vol.19
, pp. 646-655
-
-
Baker, C.S.1
Hall, R.J.2
Evans, T.J.3
-
10
-
-
0028938598
-
Pharmacodynamic profile of prostacyclin
-
Vane JR, Botting RM. Pharmacodynamic profile of prostacyclin. Am J Cardiol 1995; 75:3A-10A.
-
(1995)
Am J Cardiol
, vol.75
-
-
Vane, J.R.1
Botting, R.M.2
-
11
-
-
0023805341
-
Randomised trial of intravenous streptokinase, oral aspirin, both, or neither among 17,187 cases of suspected acute myocardial infarction: ISIS-2
-
ISIS-2 (Second International Study of Infarct Survival) Collaborative Group. Randomised trial of intravenous streptokinase, oral aspirin, both, or neither among 17,187 cases of suspected acute myocardial infarction: ISIS-2. Lancet 1988; 2:349-360.
-
(1988)
Lancet
, vol.2
, pp. 349-360
-
-
-
12
-
-
0034074730
-
Indications for early aspirin use in acute ischemic stroke: A combined analysis of 40 000 randomized patients from the chinese acute stroke trial and the international stroke trial
-
On behalf of the CAST and IST collaborative groups
-
Chen ZM, Sandercock P, Pan HC, et al. Indications for early aspirin use in acute ischemic stroke: a combined analysis of 40 000 randomized patients from the chinese acute stroke trial and the international stroke trial. On behalf of the CAST and IST collaborative groups. Stroke 2000; 31:1240-1249.
-
(2000)
Stroke
, vol.31
, pp. 1240-1249
-
-
Chen, Z.M.1
Sandercock, P.2
Pan, H.C.3
-
13
-
-
0027942293
-
Antiplatelet therapy for thromboprophylaxis: The need for careful consideration of the evidence from randomised trials
-
Antiplatelet Trialists' Collaboration
-
Collins R, Baigent C, Sandercock P, Peto R. Antiplatelet therapy for thromboprophylaxis: the need for careful consideration of the evidence from randomised trials. Antiplatelet Trialists' Collaboration. Br Med J 1994; 309:1215-1217.
-
(1994)
Br Med J
, vol.309
, pp. 1215-1217
-
-
Collins, R.1
Baigent, C.2
Sandercock, P.3
Peto, R.4
-
14
-
-
0033524421
-
Systemic biosynthesis of prostacyclin by cyclooxygenase (COX)-2: The human pharmacology of selective inhibitors of COX-2
-
McAdam BF, Catella-Lawson F, Mardini IA, et al. Systemic biosynthesis of prostacyclin by cyclooxygenase (COX)-2: The human pharmacology of selective inhibitors of COX-2. Proc Natl Acad Sci USA 1999; 96:272-277.
-
(1999)
Proc Natl Acad Sci USA
, vol.96
, pp. 272-277
-
-
McAdam, B.F.1
Catella-Lawson, F.2
Mardini, I.A.3
-
15
-
-
0032948948
-
Effects of specific inhibition of cyclooxygenase-2 on sodium balance, hemodynamics, and vasoactive eicosanoids
-
Catella-Lawson F, McAdam B, Morrison BW, et al. Effects of specific inhibition of cyclooxygenase-2 on sodium balance, hemodynamics, and vasoactive eicosanoids. J Pharmacol Exp Ther 1999; 289:735-741.
-
(1999)
J Pharmacol Exp Ther
, vol.289
, pp. 735-741
-
-
Catella-Lawson, F.1
McAdam, B.2
Morrison, B.W.3
-
16
-
-
0034900837
-
Effects of COX-2 inhibitors on aortic prostacyclin production in cholesterol-fed rabbits
-
Wong E, Huang J, Tagari P, Riendeau D. Effects of COX-2 inhibitors on aortic prostacyclin production in cholesterol-fed rabbits. Atherosclerosis 2001; 157:393-402.
-
(2001)
Atherosclerosis
, vol.157
, pp. 393-402
-
-
Wong, E.1
Huang, J.2
Tagari, P.3
Riendeau, D.4
-
17
-
-
0034702914
-
Cyclooxygenase-1 and 2-dependent prostacyclin formation in patients with atherosclerosis
-
Belton O, Byrne D, Kearney D, et al. Cyclooxygenase-1 and 2-dependent prostacyclin formation in patients with atherosclerosis. Circulation 2000; 102:840-845.
-
(2000)
Circulation
, vol.102
, pp. 840-845
-
-
Belton, O.1
Byrne, D.2
Kearney, D.3
-
18
-
-
0037134010
-
Biomedicine. Back to an aspirin a day?
-
Vane JR. Biomedicine. Back to an aspirin a day? [letter; comment]. Science 2002; 296:474-475.
-
(2002)
Science
, vol.296
, pp. 474-475
-
-
Vane, J.R.1
-
19
-
-
0034707105
-
Comparison of upper gastrointestinal toxicity of rofecoxib and naproxen in patients with rheumatoid arthritis
-
VIGOR Study Group
-
Bombardier C, Laine L, Reicin A, et al. Comparison of upper gastrointestinal toxicity of rofecoxib and naproxen in patients with rheumatoid arthritis. VIGOR Study Group. N Engl J Med 2000; 343:1520-1528.
-
(2000)
N Engl J Med
, vol.343
, pp. 1520-1528
-
-
Bombardier, C.1
Laine, L.2
Reicin, A.3
-
20
-
-
0035934070
-
Risk of cardiovascular events associated with selective COX-2 inhibitors
-
Mukherjee D, Nissen SE, Topol EJ. Risk of cardiovascular events associated with selective COX-2 inhibitors. JAMA 2001; 286:954-959.
-
(2001)
JAMA
, vol.286
, pp. 954-959
-
-
Mukherjee, D.1
Nissen, S.E.2
Topol, E.J.3
-
21
-
-
0035833502
-
The Coxibs, selective inhibitors of cyclooxygenase-2
-
FitzGerald GA, Patrono C. The Coxibs, selective inhibitors of cyclooxygenase-2. N Engl J Med 2001; 345:433-442.
-
(2001)
N Engl J Med
, vol.345
, pp. 433-442
-
-
FitzGerald, G.A.1
Patrono, C.2
-
22
-
-
0029956219
-
Elevated interleukin 6 is induced by prostaglandin E2 in a murine model of inflammation: Possible role of cyclooxygenase-2
-
Hinson RM, Williams JA, Shacter E. Elevated interleukin 6 is induced by prostaglandin E2 in a murine model of inflammation: possible role of cyclooxygenase-2. Proc Natl Acad Sci USA 1996; 93:4885-4890.
-
(1996)
Proc Natl Acad Sci USA
, vol.93
, pp. 4885-4890
-
-
Hinson, R.M.1
Williams, J.A.2
Shacter, E.3
-
23
-
-
0030454221
-
LDL stimulates chemotaxis of human monocytes through a cyclooxygenase-dependent pathway
-
Kreuzer J, Denger S, Jahn L, et al. LDL stimulates chemotaxis of human monocytes through a cyclooxygenase-dependent pathway. Arterioscler Thromb Vasc Biol 1996; 16:1481-1487.
-
(1996)
Arterioscler Thromb Vasc Biol
, vol.16
, pp. 1481-1487
-
-
Kreuzer, J.1
Denger, S.2
Jahn, L.3
-
24
-
-
0032491496
-
Activation of human orbital fibroblasts through CD40 engagement results in a dramatic induction of hyaluronan synthesis and prostaglandin endoperoxide H synthase-2 expression. Insights into potential pathogenic mechanisms of thyroid-associated ophthalmopathy
-
Cao HJ, Wang HS, Zhang Y, et al. Activation of human orbital fibroblasts through CD40 engagement results in a dramatic induction of hyaluronan synthesis and prostaglandin endoperoxide H synthase-2 expression. Insights into potential pathogenic mechanisms of thyroid-associated ophthalmopathy. J Biol Chem 1998; 273:29615-29625.
-
(1998)
J Biol Chem
, vol.273
, pp. 29615-29625
-
-
Cao, H.J.1
Wang, H.S.2
Zhang, Y.3
-
25
-
-
0035082529
-
Expression of cyclooxygenase-2 promotes the release of matrix metalloproteinase-2 and -9 in fetal rat hepatocytes
-
Callejas NA, Casado M, Diaz-Guerra MJ, etal. Expression of cyclooxygenase-2 promotes the release of matrix metalloproteinase-2 and -9 in fetal rat hepatocytes. Hepatology 2001; 33(4):860-867
-
(2001)
Hepatology
, vol.33
, Issue.4
, pp. 860-867
-
-
Callejas, N.A.1
Casado, M.2
Diaz-Guerra, M.J.3
-
26
-
-
0035374512
-
Monocyte membrane type 1-matrix metalloproteinase. Prostaglandin-dependent regulation and role in metalloproteinase-2 activation
-
Shankavaram UT, Lai WC, Netzel-Arnett S, et al. Monocyte membrane type 1-matrix metalloproteinase. Prostaglandin-dependent regulation and role in metalloproteinase-2 activation. J Biol Chem 2001; 276:19027-19032.
-
(2001)
J Biol Chem
, vol.276
, pp. 19027-19032
-
-
Shankavaram, U.T.1
Lai, W.C.2
Netzel-Arnett, S.3
-
27
-
-
0031894321
-
Extracellular matrix modulates macrophage functions characteristic to atheroma: Collagen type I enhances acquisition of resident macrophage traits by human peripheral blood monocytes in vitro
-
Wesley RB 2nd, Meng X, Godin D, Galis ZS. Extracellular matrix modulates macrophage functions characteristic to atheroma: collagen type I enhances acquisition of resident macrophage traits by human peripheral blood monocytes in vitro. Arterioscler Thromb Vasc Biol 1998; 18:432-440.
-
(1998)
Arterioscler Thromb Vasc Biol
, vol.18
, pp. 432-440
-
-
Wesley R.B. II1
Meng, X.2
Godin, D.3
Galis, Z.S.4
-
28
-
-
0028913698
-
Signal transduction in atherosclerosis: Second messengers and regulation of cellular cholesterol trafficking
-
Pomerantz KB, Nicholson AC, Hajjar DP. Signal transduction in atherosclerosis: second messengers and regulation of cellular cholesterol trafficking. Adv Exp Med Biol 1995; 369:49-64.
-
(1995)
Adv Exp Med Biol
, vol.369
, pp. 49-64
-
-
Pomerantz, K.B.1
Nicholson, A.C.2
Hajjar, D.P.3
-
29
-
-
0027290813
-
Expression of a mitogen inducible cyclooxygenase in brain neurons: Regulation by synaptic activity and glucocorticoids
-
Yamagata K, Anderson KI, Kaufman WE, et al. Expression of a mitogen inducible cyclooxygenase in brain neurons: regulation by synaptic activity and glucocorticoids. Neuron 1993; 1192:371-386.
-
(1993)
Neuron
, vol.1192
, pp. 371-386
-
-
Yamagata, K.1
Anderson, K.I.2
Kaufman, W.E.3
-
30
-
-
0015237292
-
Inhibition of prostaglandin synthesis as a mechanism of action for aspirin-like drugs
-
Vane JR. Inhibition of prostaglandin synthesis as a mechanism of action for aspirin-like drugs. Nat New Biol 1971; 231(25):232-235.
-
(1971)
Nat New Biol
, vol.231
, Issue.25
, pp. 232-235
-
-
Vane, J.R.1
-
31
-
-
0031680203
-
Preliminary study of the safety and efficacy of SC-58635, a novel cyclooxygenase 2 inhibitor: Efficacy and safety in two placebo-controlled trials in osteoarthritis and rheumatoid arthritis, and studies of gastrointestinal and platelet effects
-
Simon LS, Lanza FL, Lipsky PE, et al. Preliminary study of the safety and efficacy of SC-58635, a novel cyclooxygenase 2 inhibitor: efficacy and safety in two placebo-controlled trials in osteoarthritis and rheumatoid arthritis, and studies of gastrointestinal and platelet effects. Arthritis Rheum 1998; 41:1591-1602.
-
(1998)
Arthritis Rheum
, vol.41
, pp. 1591-1602
-
-
Simon, L.S.1
Lanza, F.L.2
Lipsky, P.E.3
-
32
-
-
0033064312
-
Characterization of rofecoxib as a cyclooxygenase-2 isoform inhibitor and demonstration of analgesia in the dental pain model
-
Ehrich EW, Dallob A, De Lepeleire I, et al. Characterization of rofecoxib as a cyclooxygenase-2 isoform inhibitor and demonstration of analgesia in the dental pain model. Clin Pharmacol Ther 1999; 65:336-347.
-
(1999)
Clin Pharmacol Ther
, vol.65
, pp. 336-347
-
-
Ehrich, E.W.1
Dallob, A.2
De Lepeleire, I.3
-
33
-
-
0032135008
-
Design of selective inhibitors of cyclooxygenase-2 as nonulcerogenic anti-inflammatory agents
-
Marnett LJ, Kalgutkar AS. Design of selective inhibitors of cyclooxygenase-2 as nonulcerogenic anti-inflammatory agents. Curr Opin Chem Biol 1998; 2:482-490.
-
(1998)
Curr Opin Chem Biol
, vol.2
, pp. 482-490
-
-
Marnett, L.J.1
Kalgutkar, A.S.2
-
34
-
-
0007667220
-
Antithrombotic therapy and progression of coronary artery disease: Antiplatelet versus antithrombins
-
Chesebro JH, Webster MI, Zoldhelyi P, et al. Antithrombotic therapy and progression of coronary artery disease: antiplatelet versus antithrombins. Circulation 1992; 86:III-100-III-111.
-
(1992)
Circulation
, vol.86
-
-
Chesebro, J.H.1
Webster, M.I.2
Zoldhelyi, P.3
-
35
-
-
0025845649
-
Low dose aspirin therapy for chronic stable angina. A randomized, placebo-controlled clinical trial
-
Ridker PM, Manson JE, Gaziano JM, et al. Low dose aspirin therapy for chronic stable angina. A randomized, placebo-controlled clinical trial. Ann Intern Med 1991; 114:835-839.
-
(1991)
Ann Intern Med
, vol.114
, pp. 835-839
-
-
Ridker, P.M.1
Manson, J.E.2
Gaziano, J.M.3
-
36
-
-
0030956673
-
Inflammation, aspirin, and the risk of cardiovascular disease in apparently healthy men
-
Ridker PM, Cushman M, Stampfer MJ, et al. Inflammation, aspirin, and the risk of cardiovascular disease in apparently healthy men. N Engl J Med 1997; 336:973-979.
-
(1997)
N Engl J Med
, vol.336
, pp. 973-979
-
-
Ridker, P.M.1
Cushman, M.2
Stampfer, M.J.3
-
37
-
-
0031743203
-
Salutary effects of aspirin in coronary artery disease are not limited to its platelet inhibitory effects
-
Mehta JL. Salutary effects of aspirin in coronary artery disease are not limited to its platelet inhibitory effects. Clin Cardiol 1998; 21:879-884.
-
(1998)
Clin Cardiol
, vol.21
, pp. 879-884
-
-
Mehta, J.L.1
-
38
-
-
0015877843
-
Anti-inflammatory drugs in experimental atherosclerosis. I. Relative potencies for inhibiting plaque formation
-
Bailey JM, Butler J. Anti-inflammatory drugs in experimental atherosclerosis. I. Relative potencies for inhibiting plaque formation. Atherosclerosis 1973; 17:515-522.
-
(1973)
Atherosclerosis
, vol.17
, pp. 515-522
-
-
Bailey, J.M.1
Butler, J.2
-
39
-
-
0037117652
-
Cyclooxygenase-2 promotes early atherosclerotic lesion formation in LDL receptor-deficient mice
-
Burleigh ME, Babaev VR, Oates JA, et al. Cyclooxygenase-2 promotes early atherosclerotic lesion formation in LDL receptor-deficient mice. Circulation 2002; 105:1816-1823.
-
(2002)
Circulation
, vol.105
, pp. 1816-1823
-
-
Burleigh, M.E.1
Babaev, V.R.2
Oates, J.A.3
-
40
-
-
0033000419
-
Oxidized low density lipoprotein suppresses expression of inducible cyclooxygenase in human macrophages
-
Eligini S, Colli S, Basso F, et al. Oxidized low density lipoprotein suppresses expression of inducible cyclooxygenase in human macrophages. Arterioscler Thromb Vasc Biol 1999; 19:1719-1725.
-
(1999)
Arterioscler Thromb Vasc Biol
, vol.19
, pp. 1719-1725
-
-
Eligini, S.1
Colli, S.2
Basso, F.3
-
41
-
-
0024437922
-
Decreased prostaglandin production by cholesterol-rich macrophages
-
Mathur SN, Albright E, Field FJ. Decreased prostaglandin production by cholesterol-rich macrophages. J Lipid Res 1989; 30:1385-1395.
-
(1989)
J Lipid Res
, vol.30
, pp. 1385-1395
-
-
Mathur, S.N.1
Albright, E.2
Field, F.J.3
-
42
-
-
0035943611
-
Prostaglandin E2 regulates the level and stability of cyclooxygenase-2 mRNA through activation of p38 mitogen-activated protein kinase in interleukin-1beta-treated human synovial fibroblasts
-
Faour WH, He Y, He QW, et al. Prostaglandin E2 regulates the level and stability of cyclooxygenase-2 mRNA through activation of p38 mitogen-activated protein kinase in interleukin-1beta-treated human synovial fibroblasts. J Biol Chem 2001; 276:31720-31731.
-
(2001)
J Biol Chem
, vol.276
, pp. 31720-31731
-
-
Faour, W.H.1
He, Y.2
He, Q.W.3
-
43
-
-
0034736007
-
Cyclooxygenase-2 expression in lipopolysaccharide-stimulated human monocytes is modulated by cyclic AMP, prostaglandin E(2), and nonsteroidal anti-inflammatory drugs
-
Hinz B, Brune K, Pahl A. Cyclooxygenase-2 expression in lipopolysaccharide-stimulated human monocytes is modulated by cyclic AMP, prostaglandin E(2), and nonsteroidal anti-inflammatory drugs. Biochem Biophys Res Commun 2000; 278:790-796.
-
(2000)
Biochem Biophys Res Commun
, vol.278
, pp. 790-796
-
-
Hinz, B.1
Brune, K.2
Pahl, A.3
-
44
-
-
0031870652
-
Macrophages in human atheroma contain PPARgamma: Differentiation-dependent peroxisomal proliferator-activated receptor gamma(PPARgamma) expression and reduction of MMP-9 activity through PPARgamma activation in mononuclear phagocytes in vitro
-
Marx N, Sukhova G, Murphy C, et al. Macrophages in human atheroma contain PPARgamma: differentiation-dependent peroxisomal proliferator-activated receptor gamma(PPARgamma) expression and reduction of MMP-9 activity through PPARgamma activation in mononuclear phagocytes in vitro. Am J Pathol 1998; 153:17-23.
-
(1998)
Am J Pathol
, vol.153
, pp. 17-23
-
-
Marx, N.1
Sukhova, G.2
Murphy, C.3
-
45
-
-
0032560545
-
Expression of the peroxisome proliferator-activated receptor gamma (PPARgamma) in human atherosclerosis and regulation in macrophages by colony stimulating factors and oxidized low density lipoprotein
-
Ricote M, Huang J, Fajas L, et al. Expression of the peroxisome proliferator-activated receptor gamma (PPARgamma) in human atherosclerosis and regulation in macrophages by colony stimulating factors and oxidized low density lipoprotein. Proc Natl Acad Sci USA 1998; 95:7614-7619.
-
(1998)
Proc Natl Acad Sci USA
, vol.95
, pp. 7614-7619
-
-
Ricote, M.1
Huang, J.2
Fajas, L.3
-
46
-
-
0032540012
-
PPAR-gamma promotes monocyte/macrophage differentiation and uptake of oxidized LDL
-
Tontonoz P, Nagy L, Alvarez JGA, et al. PPAR-gamma promotes monocyte/macrophage differentiation and uptake of oxidized LDL. Cell 1998; 93:241-252.
-
(1998)
Cell
, vol.93
, pp. 241-252
-
-
Tontonoz, P.1
Nagy, L.2
Alvarez, J.G.A.3
-
47
-
-
0034623232
-
Feedback control of cyclooxygenase-2 expression through PPARgamma
-
Inoue H, Tanabe T, Umesono K. Feedback control of cyclooxygenase-2 expression through PPARgamma. J Biol Chem 2000; 275:28028-28032.
-
(2000)
J Biol Chem
, vol.275
, pp. 28028-28032
-
-
Inoue, H.1
Tanabe, T.2
Umesono, K.3
-
48
-
-
0036079525
-
Cyclooxygenase-2-dependent prostacyclin formation is regulated by low density lipoprotein cholesterol in vitro
-
Smith LH, Boutaud O, Breyer M, et al. Cyclooxygenase-2-dependent prostacyclin formation is regulated by low density lipoprotein cholesterol in vitro. Arterioscler Thromb Vasc Biol 2002; 22:983-988.
-
(2002)
Arterioscler Thromb Vasc Biol
, vol.22
, pp. 983-988
-
-
Smith, L.H.1
Boutaud, O.2
Breyer, M.3
-
49
-
-
0033552883
-
Atherosclerosis: An inflammatory disease
-
Ross R. Atherosclerosis: an inflammatory disease. N Engl J Med 1999; 340:115-126.
-
(1999)
N Engl J Med
, vol.340
, pp. 115-126
-
-
Ross, R.1
-
50
-
-
0035853050
-
Acceleration of atherogenesis by COX-1-dependent prostanoid formation in low density lipoprotein receptor knockout mice
-
Pratico D, Tillmann C, Zhang ZB, et al. Acceleration of atherogenesis by COX-1-dependent prostanoid formation in low density lipoprotein receptor knockout mice. Proc Natl Acad Sci USA 2001; 98:3358-3363.
-
(2001)
Proc Natl Acad Sci USA
, vol.98
, pp. 3358-3363
-
-
Pratico, D.1
Tillmann, C.2
Zhang, Z.B.3
-
51
-
-
0032788729
-
Rofecoxib [Vioxx, MK-0966; 4-(4′-methylsulfonylphenyl)-3-phenyl-2-(5H)-furanone]: A potent and orally active cyclooxygenase-2 inhibitor. Pharmacological and biochemical profiles
-
Chan CC, Boyce S, Brideau C, et al. Rofecoxib [Vioxx, MK-0966; 4-(4′-methylsulfonylphenyl)-3-phenyl-2-(5H)-furanone]: a potent and orally active cyclooxygenase-2 inhibitor. Pharmacological and biochemical profiles. J Pharmacol Exp Ther 1999; 290:551-560.
-
(1999)
J Pharmacol Exp Ther
, vol.290
, pp. 551-560
-
-
Chan, C.C.1
Boyce, S.2
Brideau, C.3
-
52
-
-
0035866401
-
Chemoprevention of intestinal polyposis in the Apcdelta716 mouse by rofecoxib, a specific cyclooxygenase-2 inhibitor
-
Oshima M, Murai N, Kargman S, et al. Chemoprevention of intestinal polyposis in the Apcdelta716 mouse by rofecoxib, a specific cyclooxygenase-2 inhibitor. Cancer Res 2001; 61:1733-1740.
-
(2001)
Cancer Res
, vol.61
, pp. 1733-1740
-
-
Oshima, M.1
Murai, N.2
Kargman, S.3
-
53
-
-
0033594911
-
Nonsteroid drug selectivities for cyclo-oxygenase-1 rather than cyclo-oxygenase-2 are associated with human gastrointestinal toxicity: A full in vitro analysis
-
Warner TD, Giuliano F, Vojnovic I, et al. Nonsteroid drug selectivities for cyclo-oxygenase-1 rather than cyclo-oxygenase-2 are associated with human gastrointestinal toxicity: a full in vitro analysis. Proc Natl Acad Sci USA 1999; 96:7563-7568.
-
(1999)
Proc Natl Acad Sci USA
, vol.96
, pp. 7563-7568
-
-
Warner, T.D.1
Giuliano, F.2
Vojnovic, I.3
-
54
-
-
0030733305
-
Comparison of the cyclooxygenase-1 inhibitory properties of nonsteroidal anti-inflammatory drugs (NSAIDs) and selective COX-2 inhibitors, using sensitive microsomal and platelet assays
-
Riendeau D, Charleson S, Cromlish W, et al. Comparison of the cyclooxygenase-1 inhibitory properties of nonsteroidal anti-inflammatory drugs (NSAIDs) and selective COX-2 inhibitors, using sensitive microsomal and platelet assays. Can J Physiol Pharmacol 1997; 75:1088-1095.
-
(1997)
Can J Physiol Pharmacol
, vol.75
, pp. 1088-1095
-
-
Riendeau, D.1
Charleson, S.2
Cromlish, W.3
-
55
-
-
0028960478
-
Transgenic mice expressing high levels of human apolipoprotein B develop severe atherosclerotic lesions in response to a high-fat diet
-
Purcell-Huynh DA, Farese Jr RV, Johnson DF, et al. Transgenic mice expressing high levels of human apolipoprotein B develop severe atherosclerotic lesions in response to a high-fat diet. J Clin Invest 1995; 95:2246-2257.
-
(1995)
J Clin Invest
, vol.95
, pp. 2246-2257
-
-
Purcell-Huynh, D.A.1
Farese R.V., Jr.2
Johnson, D.F.3
-
56
-
-
0028862192
-
Quantitation of atherosclerosis in murine models: Correlation between lesions in the aortic origin and in the entire aorta, and differences in the extent of lesions between sexes in LDL receptor-deficient and apolipoprotein E-deficient mice
-
Tangirala RK, Rubin EM, Palinski W. Quantitation of atherosclerosis in murine models: correlation between lesions in the aortic origin and in the entire aorta, and differences in the extent of lesions between sexes in LDL receptor-deficient and apolipoprotein E-deficient mice. J Lipid Res 1995; 36:2320-2328.
-
(1995)
J Lipid Res
, vol.36
, pp. 2320-2328
-
-
Tangirala, R.K.1
Rubin, E.M.2
Palinski, W.3
-
57
-
-
0005111924
-
Atherosclerosis is reduced in cholesterol-fed apoE(-/-) mice administered an ASBT inhibitor or a selective COX-2 inhibitor
-
Krul ES, Napawan N, Butteiger DT, et al. Atherosclerosis is reduced in cholesterol-fed apoE(-/-) mice administered an ASBT inhibitor or a selective COX-2 inhibitor [online]. Arterioscler Thromb Vasc Biol 2002; 22:P409.
-
(2002)
Arterioscler Thromb Vasc Biol
, vol.22
-
-
Krul, E.S.1
Napawan, N.2
Butteiger, D.T.3
-
58
-
-
0031013395
-
Peroxisome proliferator-activated receptors alpha and gamma are activated by indomethacin and other non-steroidal anti-inflammatory drugs
-
Lehmann JM, Lenhard JM, Oliver BB, et al. Peroxisome proliferator-activated receptors alpha and gamma are activated by indomethacin and other non-steroidal anti-inflammatory drugs. J Biol Chem 1997; 272:3406-3410.
-
(1997)
J Biol Chem
, vol.272
, pp. 3406-3410
-
-
Lehmann, J.M.1
Lenhard, J.M.2
Oliver, B.B.3
-
59
-
-
0028944150
-
Prevention of atherosclerosis in apoE deficient mice by bone marrow transplantation
-
Linton MF, Atkinson JB, Fazio S. Prevention of atherosclerosis in apoE deficient mice by bone marrow transplantation. Science 1995; 267:1034-1037.
-
(1995)
Science
, vol.267
, pp. 1034-1037
-
-
Linton, M.F.1
Atkinson, J.B.2
Fazio, S.3
-
60
-
-
0032746178
-
Macrophage lipoprotein lipase promotes foam cell formation and atherosclerosis in vivo
-
Babaev VR, Fazio S, Gleaves LA, et al. Macrophage lipoprotein lipase promotes foam cell formation and atherosclerosis in vivo. J Clin Invest 1999; 103:1697-1705.
-
(1999)
J Clin Invest
, vol.103
, pp. 1697-1705
-
-
Babaev, V.R.1
Fazio, S.2
Gleaves, L.A.3
-
61
-
-
0034714215
-
Macrophage lipoprotein lipase promotes foam cell formation and atherosclerosis in low density lipoprotein receptor-deficient mice
-
Babaev VR, Patel MB, Semenkovich CF, et al. Macrophage lipoprotein lipase promotes foam cell formation and atherosclerosis in low density lipoprotein receptor-deficient mice. J Biol Chem 2000; 275:26293-26299.
-
(2000)
J Biol Chem
, vol.275
, pp. 26293-26299
-
-
Babaev, V.R.1
Patel, M.B.2
Semenkovich, C.F.3
-
62
-
-
0034959752
-
Lack of macrophage fatty-acid-binding protein aP2 protects mice deficient in apolipoprotein E against atherosclerosis
-
Makowski L, Boord JB, Maeda K, et al. Lack of macrophage fatty-acid-binding protein aP2 protects mice deficient in apolipoprotein E against atherosclerosis. Nat Med 2001; 7:699-705.
-
(2001)
Nat Med
, vol.7
, pp. 699-705
-
-
Makowski, L.1
Boord, J.B.2
Maeda, K.3
-
63
-
-
0032945433
-
Ischemia- and cytokine-induced mobilization of bone marrow-derived endothelial progenitor cells for neovascularization
-
Takahashi T, Kalka C, Masuda H, et al. Ischemia- and cytokine-induced mobilization of bone marrow-derived endothelial progenitor cells for neovascularization. Nat Med 1999; 5:434-438.
-
(1999)
Nat Med
, vol.5
, pp. 434-438
-
-
Takahashi, T.1
Kalka, C.2
Masuda, H.3
-
64
-
-
0034948743
-
Host bone-marrow cells are a source of donor intimal smooth-muscle-like cells in murine aortic transplant arteriopathy
-
Shimizu K, Sugiyama S, Aikawa M, et al. Host bone-marrow cells are a source of donor intimal smooth-muscle-like cells in murine aortic transplant arteriopathy. Nat Med 2001; 7:738-741.
-
(2001)
Nat Med
, vol.7
, pp. 738-741
-
-
Shimizu, K.1
Sugiyama, S.2
Aikawa, M.3
-
65
-
-
0035048053
-
Circulating smooth muscle progenitor cells contribute to atherosclerosis
-
Saiura A, Sata M, Hirata Y, et al. Circulating smooth muscle progenitor cells contribute to atherosclerosis. Nat Med 2001; 7:382-383.
-
(2001)
Nat Med
, vol.7
, pp. 382-383
-
-
Saiura, A.1
Sata, M.2
Hirata, Y.3
-
66
-
-
0036105149
-
Hematopoietic stem cells differentiate into vascular cells that participate in the pathogenesis of atherosclerosis
-
Sata M, Saiura A, Kunisato A, et al. Hematopoietic stem cells differentiate into vascular cells that participate in the pathogenesis of atherosclerosis. Nat Med 2002; 8:403-409.
-
(2002)
Nat Med
, vol.8
, pp. 403-409
-
-
Sata, M.1
Saiura, A.2
Kunisato, A.3
-
67
-
-
0037041427
-
Bone marrow cells adopt the phenotype of other cells by spontaneous cell fusion
-
Terada N, Hamazaki T, Oka M, et al. Bone marrow cells adopt the phenotype of other cells by spontaneous cell fusion. Nature 2002; 416:542-545.
-
(2002)
Nature
, vol.416
, pp. 542-545
-
-
Terada, N.1
Hamazaki, T.2
Oka, M.3
-
68
-
-
0037041406
-
Stem cells: Cell fusion causes confusion
-
Wurmser AE, Gage FH. Stem cells: cell fusion causes confusion. Nature 2002; 416:485-487.
-
(2002)
Nature
, vol.416
, pp. 485-487
-
-
Wurmser, A.E.1
Gage, F.H.2
-
69
-
-
4244043191
-
Bone marrow stem cells are a source of smooth muscle and endothelial cells in atherosclerotic lesions
-
Huebner SB, Babaev VR, Zhu T, et al. Bone marrow stem cells are a source of smooth muscle and endothelial cells in atherosclerotic lesions [online]. Arterioscler Thromb Vasc Biol 2002; 22:P339.
-
(2002)
Arterioscler Thromb Vasc Biol
, vol.22
-
-
Huebner, S.B.1
Babaev, V.R.2
Zhu, T.3
-
70
-
-
0032947918
-
Cyclooxygenase-1 and -2 are expressed by human T cells
-
Pablos JL, Santiago B, Carreira PE, et al. Cyclooxygenase-1 and -2 are expressed by human T cells. Clin Exp Immunol 1999; 115:86-90.
-
(1999)
Clin Exp Immunol
, vol.115
, pp. 86-90
-
-
Pablos, J.L.1
Santiago, B.2
Carreira, P.E.3
-
72
-
-
0030829359
-
The discovery and function of COX-2
-
Needleman P, Isakson PC. The discovery and function of COX-2. J Rheumatol 1997; 24:6-8.
-
(1997)
J Rheumatol
, vol.24
, pp. 6-8
-
-
Needleman, P.1
Isakson, P.C.2
-
73
-
-
0035103498
-
High-sensitivity C-reactive protein: A novel and promising marker of coronary heart disease
-
Rifai N, Ridker PM. High-sensitivity C-reactive protein: a novel and promising marker of coronary heart disease. Clin Chem 2001; 47:403-411.
-
(2001)
Clin Chem
, vol.47
, pp. 403-411
-
-
Rifai, N.1
Ridker, P.M.2
-
74
-
-
0035287440
-
Mouse models of hyperlipidemia and atherosclerosis
-
Fazio S, Linton MF. Mouse models of hyperlipidemia and atherosclerosis. Front Biosci 2001; 6:D515-D525.
-
(2001)
Front Biosci
, vol.6
-
-
Fazio, S.1
Linton, M.F.2
-
75
-
-
0035818601
-
Cardiovascular thrombotic events in controlled, clinical trials of rofecoxib
-
Konstam MA, Weir MR, Reicin A, et al. Cardiovascular thrombotic events in controlled, clinical trials of rofecoxib. Circulation 2001; 104:2280-2288.
-
(2001)
Circulation
, vol.104
, pp. 2280-2288
-
-
Konstam, M.A.1
Weir, M.R.2
Reicin, A.3
-
76
-
-
0034644396
-
Gastrointestinal toxicity with celecoxib vs nonsteroidal anti-inflammatory drugs for osteoarthritis and rheumatoid arthritis: The class study: A randomized controlled trial. Celecoxib Long-term Arthritis Safety Study
-
Silverstein FE, Faich G, Goldstein JL, et al. Gastrointestinal toxicity with celecoxib vs nonsteroidal anti-inflammatory drugs for osteoarthritis and rheumatoid arthritis: the class study: a randomized controlled trial. Celecoxib Long-term Arthritis Safety Study. JAMA 2000; 284:1247-1255.
-
(2000)
JAMA
, vol.284
, pp. 1247-1255
-
-
Silverstein, F.E.1
Faich, G.2
Goldstein, J.L.3
-
77
-
-
0037047119
-
Efficacy assessment of meloxicam, a preferential cyclooxygenase-2 inhibitor, in acute coronary syndromes without ST-segment elevation
-
Altman R, Luciardi HL, Muntaner J, et al. Efficacy assessment of meloxicam, a preferential cyclooxygenase-2 inhibitor, in acute coronary syndromes without ST-segment elevation. Circulation 2002; 106:191-195.
-
(2002)
Circulation
, vol.106
, pp. 191-195
-
-
Altman, R.1
Luciardi, H.L.2
Muntaner, J.3
-
78
-
-
0037134011
-
Role of prostacyclin in the cardiovascular response to thromboxane A2
-
Cheng Y, Austin SC, Rocca B, et al. Role of prostacyclin in the cardiovascular response to thromboxane A2. Science 2002; 296:539-541.
-
(2002)
Science
, vol.296
, pp. 539-541
-
-
Cheng, Y.1
Austin, S.C.2
Rocca, B.3
-
79
-
-
0035924765
-
Cyclooxygenase inhibitors and the antiplatelet effects of aspirin
-
Catella-Lawson F, Reilly MP, Kapoor SC, et al. Cyclooxygenase inhibitors and the antiplatelet effects of aspirin. New Engl J Med 2001; 345:1809-1817.
-
(2001)
New Engl J Med
, vol.345
, pp. 1809-1817
-
-
Catella-Lawson, F.1
Reilly, M.P.2
Kapoor, S.C.3
-
80
-
-
0037030666
-
Cost effectiveness of aspirin, clopidogrel, or both for secondary prevention of coronary heart disease
-
Gaspoz J-M, Coxson PG, Goldman PA, et al. Cost effectiveness of aspirin, clopidogrel, or both for secondary prevention of coronary heart disease. N Engl J Med 2002; 346:1800-1806.
-
(2002)
N Engl J Med
, vol.346
, pp. 1800-1806
-
-
Gaspoz, J.-M.1
Coxson, P.G.2
Goldman, P.A.3
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