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Volumn 45, Issue 6, 2020, Pages 606-612

The effect of the artificial sweeteners on glucose metabolism in healthy adults: A randomized, double-blinded, crossover clinical trial

Author keywords

Active GLP 1; Aspartame; Glucose; Glucose metabolism; Insulin; Leptin; Non nutritive sweetener; Protocol; Sucralose

Indexed keywords

ASPARTAME; SUCROSE; SWEETENING AGENT; TRICHLOROSUCROSE;

EID: 85083677963     PISSN: 17155312     EISSN: 17155320     Source Type: Journal    
DOI: 10.1139/apnm-2019-0359     Document Type: Article
Times cited : (24)

References (48)
  • 1
    • 52149107761 scopus 로고    scopus 로고
    • Splenda alters gut microflora and increases intestinal p-glycoprotein and cytochrome p-450 in male rats
    • Abou-Donia, M.B., El-Masry, E.M., Abdel-Rahman, A.A., McLendon, R.E., and Schiffman, S.S. 2008. Splenda alters gut microflora and increases intestinal p-glycoprotein and cytochrome p-450 in male rats. J. Toxicol. Environ. Health A, 71(21): 1415-1429. doi:10.1080/15287390802328630.
    • (2008) J. Toxicol. Environ. Health A , vol.71 , Issue.21 , pp. 1415-1429
    • Abou-Donia, M.B.1    El-Masry, E.M.2    Abdel-Rahman, A.A.3    McLendon, R.E.4    Schiffman, S.S.5
  • 2
    • 85067213751 scopus 로고    scopus 로고
    • Recent evidence for the effects of nonnutritive sweeteners on glycaemic control
    • Ahmad, S.Y., Azad, M.B., Friel, J., and MacKay, D. 2019. Recent evidence for the effects of nonnutritive sweeteners on glycaemic control. Curr. Opin. Clin. Nutr. Metab. Care, 22(4): 278-283. doi:10.1097/mco.0000000000000566.
    • (2019) Curr. Opin. Clin. Nutr. Metab. Care , vol.22 , Issue.4 , pp. 278-283
    • Ahmad, S.Y.1    Azad, M.B.2    Friel, J.3    Mackay, D.4
  • 3
    • 0028931893 scopus 로고
    • The use of areas under curves in diabetes research
    • Allison, D.B., Paultre, F., Maggio, C., Mezzitis, N., and Pi-Sunyer, F.X. 1995. The use of areas under curves in diabetes research. Diabetes Care, 18(2): 245-250. doi:10.2337/diacare.18.2.245.
    • (1995) Diabetes Care , vol.18 , Issue.2 , pp. 245-250
    • Allison, D.B.1    Paultre, F.2    Maggio, C.3    Mezzitis, N.4    Pi-Sunyer, F.X.5
  • 4
    • 77953962912 scopus 로고    scopus 로고
    • Effects of stevia, aspartame, and sucrose on food intake, satiety, and postprandial glucose and insulin levels
    • Anton, S.D., Martin, C.K., Han, H., Coulon, S., Cefalu, W.T., Geiselman, P., and Williamson, D.A. 2010. Effects of stevia, aspartame, and sucrose on food intake, satiety, and postprandial glucose and insulin levels. Appetite, 55(1): 37-43. doi:10.1016/j.appet.2010.03.009.
    • (2010) Appetite , vol.55 , Issue.1 , pp. 37-43
    • Anton, S.D.1    Martin, C.K.2    Han, H.3    Coulon, S.4    Cefalu, W.T.5    Geiselman, P.6    Williamson, D.A.7
  • 5
    • 85024388503 scopus 로고    scopus 로고
    • Nonnutritive sweeteners and cardiometabolic health: A systematic review and meta-analysis of randomized controlled trials and prospective cohort studies
    • Azad, M.B., Abou-Setta, A.M., Chauhan, B.F., Rabbani, R., Lys, J., Copstein, L., et al. 2017. Nonnutritive sweeteners and cardiometabolic health: A systematic review and meta-analysis of randomized controlled trials and prospective cohort studies. CMAJ, 189(28): E929-E939. doi:10.1503/cmaj.161390.
    • (2017) CMAJ , vol.189 , Issue.28 , pp. E929-E939
    • Azad, M.B.1    Abou-Setta, A.M.2    Chauhan, B.F.3    Rabbani, R.4    Lys, J.5    Copstein, L.6
  • 6
    • 0034043197 scopus 로고    scopus 로고
    • Repeated dose study of sucralose tolerance in human subjects
    • Baird, I.M., Shephard, N.W., Merritt, R.J., and Hildick-Smith, G. 2000. Repeated dose study of sucralose tolerance in human subjects. Food Chem. Toxicol. 38(Suppl. 2): S123-S129. doi:10.1016/S0278-6915(00)00035-1.
    • (2000) Food Chem. Toxicol , vol.38 , Issue.2 , pp. S123-S129
    • Baird, I.M.1    Shephard, N.W.2    Merritt, R.J.3    Hildick-Smith, G.4
  • 7
    • 20444507616 scopus 로고    scopus 로고
    • Can artificial sweeteners help control body weight and prevent obesity?
    • Benton, D. 2005. Can artificial sweeteners help control body weight and prevent obesity? Nutr. Res. Rev. 18(1): 63-76. doi:10.1079/NRR200494.
    • (2005) Nutr. Res. Rev , vol.18 , Issue.1 , pp. 63-76
    • Benton, D.1
  • 8
    • 85055585025 scopus 로고    scopus 로고
    • Consumption of a carbonated beverage with high-intensity sweeteners has no effect on insulin sensitivity and secretion in nondiabetic adults
    • Bonnet, F., Tavenard, A., Esvan, M., Laviolle, B., Viltard, M., Lepicard, E.M., and Laine, F. 2018. Consumption of a carbonated beverage with high-intensity sweeteners has no effect on insulin sensitivity and secretion in nondiabetic adults. J. Nutr. 148(8): 1293-1299. doi:10.1093/jn/nxy100.
    • (2018) J. Nutr , vol.148 , Issue.8 , pp. 1293-1299
    • Bonnet, F.1    Tavenard, A.2    Esvan, M.3    Laviolle, B.4    Viltard, M.5    Lepicard, E.M.6    Laine, F.7
  • 9
    • 83355175428 scopus 로고    scopus 로고
    • Short-term consumption of sucralose, a nonnutritive sweetener, is similar to water with regard to select markers of hunger signaling and short-term glucose homeostasis in women
    • Brown, A.W., Brown, M.M.B., Onken, K.L., and Beitz, D.C. 2011. Short-term consumption of sucralose, a nonnutritive sweetener, is similar to water with regard to select markers of hunger signaling and short-term glucose homeostasis in women. Nutr. Res. 31(12): 882-888. doi:10.1016/j.nutres.2011.10.004.
    • (2011) Nutr. Res , vol.31 , Issue.12 , pp. 882-888
    • Brown, A.W.1    Brown, M.M.B.2    Onken, K.L.3    Beitz, D.C.4
  • 10
    • 72249115786 scopus 로고    scopus 로고
    • Ingestion of diet soda before a glucose load augments glucagon-like peptide-1 secretion
    • Brown, R.J., Walter, M., and Rother, K.I. 2009. Ingestion of diet soda before a glucose load augments glucagon-like peptide-1 secretion. Diabetes Care, 32(12): 2184-2186. doi:10.2337/dc09-1185.
    • (2009) Diabetes Care , vol.32 , Issue.12 , pp. 2184-2186
    • Brown, R.J.1    Walter, M.2    Rother, K.I.3
  • 11
    • 84862077774 scopus 로고    scopus 로고
    • Effects of diet soda on gut hormones in youths with diabetes
    • Brown, R.J., Walter, M., and Rother, K.I. 2012. Effects of diet soda on gut hormones in youths with diabetes. Diabetes Care, 35(5): 959-964. doi:10.2337/dc11-2424.
    • (2012) Diabetes Care , vol.35 , Issue.5 , pp. 959-964
    • Brown, R.J.1    Walter, M.2    Rother, K.I.3
  • 12
    • 84899988056 scopus 로고    scopus 로고
    • Non-nutritive sweeteners: No class effect on the glycaemic or appetite responses to ingested glucose
    • Bryant, C.E., Wasse, L.K., Astbury, N., Nandra, G., and McLaughlin, J.T. 2014. Non-nutritive sweeteners: No class effect on the glycaemic or appetite responses to ingested glucose. Eur. J. Clin. Nutr. 68(5): 629-631. doi:10.1038/ejcn.2014.19.
    • (2014) Eur. J. Clin. Nutr , vol.68 , Issue.5 , pp. 629-631
    • Bryant, C.E.1    Wasse, L.K.2    Astbury, N.3    Nandra, G.4    McLaughlin, J.T.5
  • 13
    • 0024452674 scopus 로고
    • Metabolic effects of adding sucrose and aspartame to the diet of subjects with noninsulin-dependent diabetes mellitus
    • Colagiuri, S., Miller, J.J., and Edwards, R.A. 1989. Metabolic effects of adding sucrose and aspartame to the diet of subjects with noninsulin-dependent diabetes mellitus. Am. J. Clin. Nutr. 50(3): 474-478. doi:10.1093/ajcn/50.3.474.
    • (1989) Am. J. Clin. Nutr , vol.50 , Issue.3 , pp. 474-478
    • Colagiuri, S.1    Miller, J.J.2    Edwards, R.A.3
  • 14
    • 0024375983 scopus 로고
    • Menstrual cyclicity has a profound effect on glucose homeostasis
    • Diamond, M.P., Simonson, D.C., and DeFronzo, R.A. 1989. Menstrual cyclicity has a profound effect on glucose homeostasis. Fertil. Steril. 52(2): 204-208. doi: 10.1016/S0015-0282(16)60842-7.
    • (1989) Fertil. Steril , vol.52 , Issue.2 , pp. 204-208
    • Diamond, M.P.1    Simonson, D.C.2    Defronzo, R.A.3
  • 16
    • 84864394039 scopus 로고    scopus 로고
    • Nonnutritive sweeteners: Current use and health perspectives: A scientific statement from the American heart association and the American diabetes association
    • Gardner, C., Wylie-Rosett, J., Gidding, S.S., Steffen, L.M., Johnson, R.K., Reader, D., and Lichtenstein, A.H. 2012. Nonnutritive sweeteners: Current use and health perspectives: A scientific statement from the American heart association and the American diabetes association. Diabetes Care, 35(8): 1798-1808. doi:10.2337/dc12-9002.
    • (2012) Diabetes Care , vol.35 , Issue.8 , pp. 1798-1808
    • Gardner, C.1    Wylie-Rosett, J.2    Gidding, S.S.3    Steffen, L.M.4    Johnson, R.K.5    Reader, D.6    Lichtenstein, A.H.7
  • 17
    • 61449225540 scopus 로고    scopus 로고
    • Beverage consumption of Canadian adults
    • Garriguet, D. 2008. Beverage consumption of Canadian adults. Health Rep. 19(4): 23-29.
    • (2008) Health Rep , vol.19 , Issue.4 , pp. 23-29
    • Garriguet, D.1
  • 18
    • 85070944988 scopus 로고    scopus 로고
    • Lists of Permitted Food Additives
    • Government of Canada. 2019. List of Permitted Sweeteners (Lists of Permitted Food Additives). Available from https://www.canada.ca/en/health-canada/services/food-nutrition/food-safety/food-additives/lists-permitted/9-sweeteners.html. [Accessed 3 April 2019.].
    • (2019) List of Permitted Sweeteners
  • 19
    • 0347361497 scopus 로고    scopus 로고
    • Lack of effect of sucralose on glucose homeostasis in subjects with type 2 diabetes
    • Grotz, V.L., Henry, R.R., McGill, J.B., Prince, M.J., Shamoon, H., Trout, J.R., and Pi-Sunyer, F.X. 2003. Lack of effect of sucralose on glucose homeostasis in subjects with type 2 diabetes. J. Am. Diet Assoc. 103(12): 1607-1612. doi:10.1016/j.jada.2003.09.021.
    • (2003) J. Am. Diet Assoc , vol.103 , Issue.12 , pp. 1607-1612
    • Grotz, V.L.1    Henry, R.R.2    McGill, J.B.3    Prince, M.J.4    Shamoon, H.5    Trout, J.R.6    Pi-Sunyer, F.X.7
  • 20
    • 85019613060 scopus 로고    scopus 로고
    • A 12-week randomized clinical trial investigating the potential for sucralose to affect glucose homeostasis
    • Grotz, V.L., Pi-Sunyer, X., Porte, D., Roberts, A., and Trout, J.R. 2017. A 12-week randomized clinical trial investigating the potential for sucralose to affect glucose homeostasis. Regul. Toxicol. Pharmacol. 88: 22-33. doi:10.1016/j.yrtph.2017.05.011.
    • (2017) Regul. Toxicol. Pharmacol , vol.88 , pp. 22-33
    • Grotz, V.L.1    Pi-Sunyer, X.2    Porte, D.3    Roberts, A.4    Trout, J.R.5
  • 21
    • 0038018379 scopus 로고    scopus 로고
    • Physiological mechanisms mediating aspartame-induced satiety. Physiol
    • Hall, W.L., Millward, D.J., Rogers, P.J., and Morgan, L.M. 2003. Physiological mechanisms mediating aspartame-induced satiety. Physiol. Behav. 78(4-5): 557-562. doi:10.1016/s0031-9384(03)00034-9.
    • (2003) Behav , vol.78 , Issue.4-5 , pp. 557-562
    • Hall, W.L.1    Millward, D.J.2    Rogers, P.J.3    Morgan, L.M.4
  • 22
    • 85045677540 scopus 로고    scopus 로고
    • Aspartame consumption for 12 weeks does not affect glycemia, appetite, or body weight of healthy, lean adults in a randomized controlled trial
    • Higgins, K.A., Considine, R.V., and Mattes, R.D. 2018. Aspartame consumption for 12 weeks does not affect glycemia, appetite, or body weight of healthy, lean adults in a randomized controlled trial. J. Nutr. 148(4): 650-657. doi:10.1093/jn/nxy021.
    • (2018) J. Nutr , vol.148 , Issue.4 , pp. 650-657
    • Higgins, K.A.1    Considine, R.V.2    Mattes, R.D.3
  • 23
    • 0023892843 scopus 로고
    • Response to single dose of aspartame or saccharin by NIDDM patients
    • Horwitz, D.L., McLane, M., and Kobe, P. 1988. Response to single dose of aspartame or saccharin by NIDDM patients. Diabetes Care, 11(3): 230-234. doi:10.2337/diacare.11.3.230.
    • (1988) Diabetes Care , vol.11 , Issue.3 , pp. 230-234
    • Horwitz, D.L.1    McLane, M.2    Kobe, P.3
  • 24
    • 85049451401 scopus 로고    scopus 로고
    • Effects of sucralose on insulin and glucagon-like peptide-1 secretion in healthy subjects: A randomized, double-blind, placebocontrolled trial
    • Lertrit, A., Srimachai, S., Saetung, S., Chanprasertyothin, S., Chailurkit, L.O., Areevut, C., et al. 2018. Effects of sucralose on insulin and glucagon-like peptide-1 secretion in healthy subjects: A randomized, double-blind, placebocontrolled trial. Nutrition, 55-56: 125-130. doi:10.1016/j.nut.2018.04.001.
    • (2018) Nutrition , pp. 125-130
    • Lertrit, A.1    Srimachai, S.2    Saetung, S.3    Chanprasertyothin, S.4    Chailurkit, L.O.5    Areevut, C.6
  • 25
    • 85012935675 scopus 로고    scopus 로고
    • The Comparative reliability and feasibility of the past-year canadian diet history questionnaire II: Comparison of the paper and web versions
    • Lo Siou, G., Csizmadi, I., Boucher, B.A., Akawung, A.K., Whelan, H.K., Sharma, M., et al. 2017. The Comparative reliability and feasibility of the past-year canadian diet history questionnaire II: Comparison of the paper and web versions. Nutrients, 9(2): E133. doi:10.3390/nu9020133.
    • (2017) Nutrients , vol.9 , Issue.2
    • Lo Siou, G.1    Csizmadi, I.2    Boucher, B.A.3    Akawung, A.K.4    Whelan, H.K.5    Sharma, M.6
  • 26
    • 58149397890 scopus 로고    scopus 로고
    • Nonnutritive sweetener consumption in humans: Effects on appetite and food intake and their putative mechanisms
    • Mattes, R.D., and Popkin, B.M. 2009. Nonnutritive sweetener consumption in humans: Effects on appetite and food intake and their putative mechanisms. Am. J. Clin. Nutr. 89(1): 1-14. doi:10.3945/ajcn.2008.26792.
    • (2009) Am. J. Clin. Nutr , vol.89 , Issue.1 , pp. 1-14
    • Mattes, R.D.1    Popkin, B.M.2
  • 27
    • 0021813187 scopus 로고
    • Homeostasis model assessment: Insulin resistance and beta-cell function from fasting plasma glucose and insulin concentrations in man
    • Matthews, D.R., Hosker, J.P., Rudenski, A.S., Naylor, B.A., Treacher, D.F., and Turner, R.C. 1985. Homeostasis model assessment: Insulin resistance and beta-cell function from fasting plasma glucose and insulin concentrations in man. Diabetologia, 28(7): 412-419. doi:10.1007/bf00280883.
    • (1985) Diabetologia , vol.28 , Issue.7 , pp. 412-419
    • Matthews, D.R.1    Hosker, J.P.2    Rudenski, A.S.3    Naylor, B.A.4    Treacher, D.F.5    Turner, R.C.6
  • 28
    • 0032786181 scopus 로고    scopus 로고
    • Blood glucose and meal patterns in time-blinded males, after aspartame, carbohydrate, and fat consumption, in relation to sweetness perception
    • Melanson, K.J., Westerterp-Plantenga, M.S., Campfield, L.A., and Saris, W.H. 1999. Blood glucose and meal patterns in time-blinded males, after aspartame, carbohydrate, and fat consumption, in relation to sweetness perception. Br. J. Nutr. 82(6): 437-446. doi:10.1017/S0007114599001695.
    • (1999) Br. J. Nutr , vol.82 , Issue.6 , pp. 437-446
    • Melanson, K.J.1    Westerterp-Plantenga, M.S.2    Campfield, L.A.3    Saris, W.H.4
  • 29
    • 0025897513 scopus 로고
    • Effect of aspartame and protein, administered in phenylalanineequivalent doses, on plasma neutral amino acids, aspartate, insulin and glucose in man
    • Moller, S.E. 1991. Effect of aspartame and protein, administered in phenylalanineequivalent doses, on plasma neutral amino acids, aspartate, insulin and glucose in man. Pharmacol. Toxicol. 68(5): 408-412. doi:10.1111/j.1600-0773.1991.tb01262.x.
    • (1991) Pharmacol. Toxicol , vol.68 , Issue.5 , pp. 408-412
    • Moller, S.E.1
  • 30
    • 65349147617 scopus 로고    scopus 로고
    • Diet soda intake and risk of incident metabolic syndrome and type 2 diabetes in the multi-ethnic study of atherosclerosis (MESA)
    • Nettleton, J.A., Lutsey, P.L., Wang, Y., Lima, J.A., Michos, E.D., and Jacobs, D.R. 2009. Diet soda intake and risk of incident metabolic syndrome and type 2 diabetes in the multi-ethnic study of atherosclerosis (MESA). Diabetes Care, 32(4): 688-694. doi:10.2337/dc08-1799.
    • (2009) Diabetes Care , vol.32 , Issue.4 , pp. 688-694
    • Nettleton, J.A.1    Lutsey, P.L.2    Wang, Y.3    Lima, J.A.4    Michos, E.D.5    Jacobs, D.R.6
  • 31
    • 84870207305 scopus 로고    scopus 로고
    • Beverage consumption patterns of Canadian adults aged 19 to 65 years
    • Nikpartow, N., Danyliw, A.D., Whiting, S.J., Lim, H.J., and Vatanparast, H. 2012. Beverage consumption patterns of Canadian adults aged 19 to 65 years. Public Health Nutr. 15(12): 2175-2184. doi:10.1017/s1368980012003898.
    • (2012) Public Health Nutr , vol.15 , Issue.12 , pp. 2175-2184
    • Nikpartow, N.1    Danyliw, A.D.2    Whiting, S.J.3    Lim, H.J.4    Vatanparast, H.5
  • 32
    • 84907999777 scopus 로고    scopus 로고
    • Low-dose aspartame consumption differentially affects gut microbiotahost metabolic interactions in the diet-induced obese rat
    • Palmnas, M.S., Cowan, T.E., Bomhof, M.R., Su, J., Reimer, R.A., Vogel, H.J., et al. 2014. Low-dose aspartame consumption differentially affects gut microbiotahost metabolic interactions in the diet-induced obese rat. PLoS One, 9(10): E109841. doi:10.1371/journal.pone.0109841.
    • (2014) Plos One , vol.9 , Issue.10
    • Palmnas, M.S.1    Cowan, T.E.2    Bomhof, M.R.3    Su, J.4    Reimer, R.A.5    Vogel, H.J.6
  • 33
    • 84885194132 scopus 로고    scopus 로고
    • Sucralose affects glycemic and hormonal responses to an oral glucose load
    • Pepino, M.Y., Tiemann, C.D., Patterson, B.W., Wice, B.M., and Klein, S. 2013. Sucralose affects glycemic and hormonal responses to an oral glucose load. Diabetes Care, 36(9): 2530-2535. doi:10.2337/dc12-2221.
    • (2013) Diabetes Care , vol.36 , Issue.9 , pp. 2530-2535
    • Pepino, M.Y.1    Tiemann, C.D.2    Patterson, B.W.3    Wice, B.M.4    Klein, S.5
  • 35
    • 84984972714 scopus 로고    scopus 로고
    • Effects of the non-nutritive sweeteners on glucose metabolism and appetite regulating hormones: Systematic review of observational prospective studies and clinical trials
    • Romo-Romo, A., Aguilar-Salinas, C.A., Brito-Cordova, G.X., Diaz, R.A.G., Valentin, D.V., and Almeda-Valdes, P. 2016. Effects of the non-nutritive sweeteners on glucose metabolism and appetite regulating hormones: Systematic review of observational prospective studies and clinical trials. PLoS One, 11(8): E0161264. doi:10.1371/journal.pone.0161264.
    • (2016) Plos One , vol.11 , Issue.8
    • Romo-Romo, A.1    Aguilar-Salinas, C.A.2    Brito-Cordova, G.X.3    Diaz, R.A.G.4    Valentin, D.V.5    Almeda-Valdes, P.6
  • 37
    • 85027831361 scopus 로고    scopus 로고
    • Metabolic effects of aspartame in adulthood: A systematic review and meta-analysis of randomized clinical trials
    • Santos, N.C., de Araujo, L.M., Canto, G.L., Guerra, E.N.S., Coelho, M.S., and Borin, M.F. 2018. Metabolic effects of aspartame in adulthood: A systematic review and meta-analysis of randomized clinical trials. Crit. Rev. Food Sci. Nutr. 58(12): 2068-2081. doi:10.1080/10408398.2017.1304358.
    • (2018) Crit. Rev. Food Sci. Nutr , vol.58 , Issue.12 , pp. 2068-2081
    • Santos, N.C.1    De Araujo, L.M.2    Canto, G.L.3    Guerra, E.N.S.4    Coelho, M.S.5    Borin, M.F.6
  • 38
    • 84908325271 scopus 로고    scopus 로고
    • Artificial sweeteners induce glucose intolerance by altering the gut microbiota
    • Suez, J., Korem, T., Zeevi, D., Zilberman-Schapira, G., Thaiss, C.A., Maza, O., et al. 2014. Artificial sweeteners induce glucose intolerance by altering the gut microbiota. Nature, 514(7521): 181-186. doi:10.1038/nature13793.
    • (2014) Nature , vol.514 , Issue.7521 , pp. 181-186
    • Suez, J.1    Korem, T.2    Zeevi, D.3    Zilberman-Schapira, G.4    Thaiss, C.A.5    Maza, O.6
  • 39
    • 84883183253 scopus 로고    scopus 로고
    • Artificial sweeteners produce the counterintuitive effect of inducing metabolic derangements
    • Swithers, S.E. 2013. Artificial sweeteners produce the counterintuitive effect of inducing metabolic derangements. Trends Endocrinol. Metab. 24(9): 431-441. doi:10.1016/j.tem.2013.05.005.
    • (2013) Trends Endocrinol. Metab , vol.24 , Issue.9 , pp. 431-441
    • Swithers, S.E.1
  • 40
    • 67949100464 scopus 로고    scopus 로고
    • General and persistent effects of high-intensity sweeteners on body weight gain and caloric compensation in rats
    • Swithers, S.E., Baker, C.R., and Davidson, T.L. 2009. General and persistent effects of high-intensity sweeteners on body weight gain and caloric compensation in rats. Behav. Neurosci. 123(4): 772-780. doi:10.1037/a0016139.
    • (2009) Behav. Neurosci , vol.123 , Issue.4 , pp. 772-780
    • Swithers, S.E.1    Baker, C.R.2    Davidson, T.L.3
  • 41
    • 77949789393 scopus 로고    scopus 로고
    • High-intensity sweeteners and energy balance
    • Swithers, S.E., Martin, A.A., and Davidson, T.L. 2010. High-intensity sweeteners and energy balance. Physiol. Behav. 100(1): 55-62. doi:10.1016/j.physbeh.2009.12.021.
    • (2010) Physiol. Behav , vol.100 , Issue.1 , pp. 55-62
    • Swithers, S.E.1    Martin, A.A.2    Davidson, T.L.3
  • 42
    • 84992046740 scopus 로고    scopus 로고
    • Hormonal responses to non-nutritive sweeteners in water and diet soda
    • Sylvetsky, A.C., Brown, R.J., Blau, J.E., Walter, M., and Rother, K.I. 2016. Hormonal responses to non-nutritive sweeteners in water and diet soda. Nutr. Metab. 13: 71. doi:10.1186/s12986-016-0129-3.
    • (2016) Nutr. Metab , vol.13 , pp. 71
    • Sylvetsky, A.C.1    Brown, R.J.2    Blau, J.E.3    Walter, M.4    Rother, K.I.5
  • 43
    • 84922232978 scopus 로고    scopus 로고
    • Sucralose enhances GLP-1 release and lowers blood glucose in the presence of carbohydrate in healthy subjects but not in patients with type 2 diabetes
    • Temizkan, S., Deyneli, O., Yasar, M., Arpa, M., Gunes, M., Yazici, D., et al. 2015. Sucralose enhances GLP-1 release and lowers blood glucose in the presence of carbohydrate in healthy subjects but not in patients with type 2 diabetes. Eur. J. Clin. Nutr. 69(2): 162-166. doi:10.1038/ejcn.2014.208.
    • (2015) Eur. J. Clin. Nutr , vol.69 , Issue.2 , pp. 162-166
    • Temizkan, S.1    Deyneli, O.2    Yasar, M.3    Arpa, M.4    Gunes, M.5    Yazici, D.6
  • 44
    • 85017094502 scopus 로고    scopus 로고
    • Effects of non-nutritive (Artificial vs natural) sweeteners on 24-h glucose profiles
    • Tey, S.L., Salleh, N.B., Henry, C.J., and Forde, C.G. 2017. Effects of non-nutritive (artificial vs natural) sweeteners on 24-h glucose profiles. Eur. J. Clin. Nutr. 71(9): 1129-1132. doi:10.1038/ejcn.2017.37.
    • (2017) Eur. J. Clin. Nutr , vol.71 , Issue.9 , pp. 1129-1132
    • Tey, S.L.1    Salleh, N.B.2    Henry, C.J.3    Forde, C.G.4
  • 46
    • 84455160918 scopus 로고    scopus 로고
    • Effects of different sweet preloads on incretin hormone secretion, gastric emptying, and postprandial glycemia in healthy humans
    • Wu, T., Zhao, B.R., Bound, M.J., Checklin, H.L., Bellon, M., Little, T.J., et al. 2012. Effects of different sweet preloads on incretin hormone secretion, gastric emptying, and postprandial glycemia in healthy humans. Am. J. Clin. Nutr. 95(1): 78-83. doi:10.3945/ajcn.111.021543.
    • (2012) Am. J. Clin. Nutr , vol.95 , Issue.1 , pp. 78-83
    • Wu, T.1    Zhao, B.R.2    Bound, M.J.3    Checklin, H.L.4    Bellon, M.5    Little, T.J.6
  • 47
    • 84891881412 scopus 로고    scopus 로고
    • Artificial sweeteners have no effect on gastric emptying, glucagon-like peptide-1, or glycemia after oral glucose in healthy humans
    • Wu, T., Bound, M.J., Standfield, S.D., Bellon, M., Young, R.L., Jones, K.L., et al. 2013. Artificial sweeteners have no effect on gastric emptying, glucagon-like peptide-1, or glycemia after oral glucose in healthy humans. Diabetes Care, 36(12): E202-e203. doi:10.2337/dc13-0958.
    • (2013) Diabetes Care , vol.36 , Issue.12 , pp. e202-e203
    • Wu, T.1    Bound, M.J.2    Standfield, S.D.3    Bellon, M.4    Young, R.L.5    Jones, K.L.6
  • 48
    • 80052738533 scopus 로고    scopus 로고
    • Relative validities of 3-day food records and the food frequency questionnaire
    • Yang, Y.J., Kim, M.K., Hwang, S.H., Ahn, Y., Shim, J.E., and Kim, D.H. 2010. Relative validities of 3-day food records and the food frequency questionnaire. Nutr. Res. Pract. 4(2): 142-148. doi:10.4162/nrp.2010.4.2.142.
    • (2010) Nutr. Res. Pract , vol.4 , Issue.2 , pp. 142-148
    • Yang, Y.J.1    Kim, M.K.2    Hwang, S.H.3    Ahn, Y.4    Shim, J.E.5    Kim, D.H.6


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