Scientific Opinion on Dietary Reference Values for zinc

EFSA Journal

Volumn 12, Issue 10, 2014, Pages

[No Author Info available]

Author keywords

Dietary Reference Value; phytate; Population Reference Intake; zinc

Indexed keywords

EID: 85078379422     PISSN: None     EISSN: 18314732     Source Type: Journal    
DOI: 10.2903/j.efsa.2014.3844     Document Type: Article

References (190)

1. Adams CL, Hambidge M, Raboy V, Dorsch JA, Sian L, Westcott JL and Krebs NF, 2002. Zinc absorption from a low-phytic acid maize. American Journal of Clinical Nutrition, 76, 556–559.
2. Afssa (Agence française de sécurité sanitaire des aliments), 2001. Apports nutritionnels conseillés pour la population française. Editions Tec&Doc, Paris, France, 605 pp.
3. Amcoff E, Edberg A, Enghardt Barbieri H, Lindroos A, Nälsén C, Pearson M and Warensjö Lemming E (Livsmedelsverket), 2012. Riksmaten – vuxna 2010–11. Livsmedels- och näringsintag bland vuxna i Sverige. Resultat från matvaneundersökning utförd 2010-11. 180 pp.
4. Amirabdollahian F and Ash R, 2010. An estimate of phytate intake and molar ratio of phytate to zinc in the diet of the people in the United Kingdom. Public Health Nutrition, 13, 1380–1388.
5. Avellini BA, Kamon E and Krajewski JT, 1980. Physiological responses of physically fit men and women to acclimation to humid heat. Journal of Applied Physiology: Respiratory, Environmental and Exercise Physiology, 49, 254–261.
6. Bates B, Lennox A, Prentice A, Bates C and Swan G, 2012. National Diet and Nutrition Survey. Headline results from Years 1, 2 and 3 (combined) of the Rolling Programme (2008/2009 – 2010/11). A survey carried out on behalf of the Department of Health and the Food Standards Agency. 79 pp.
7. Bates CJ and Tsuchiya H, 1990. Zinc in breast milk during prolonged lactation: comparison between the UK and the Gambia. European Journal of Clinical Nutrition, 44, 61–69.
8. Beck FW, Prasad AS, Kaplan J, Fitzgerald JT and Brewer GJ, 1997a. Changes in cytokine production and T cell subpopulations in experimentally induced zinc-deficient humans. American Journal of Physiology, 272, E1002–1007.
9. Beck FW, Kaplan J, Fine N, Handschu W and Prasad AS, 1997b. Decreased expression of CD73 (ecto-5′-nucleotidase) in the CD8+ subset is associated with zinc deficiency in human patients. Journal of Laboratory and Clinical Medicine, 130, 147–156.
10. Bieri A, Petkovic V, Miletta MC, Fluck CE and Mullis PE, 2013. Short stature and GH deficiency caused by zinc deficiency in a 6-month-old breast-fed infant due to a dominant negative heterozygous G87R mutation in the Zinc Transporter ZnT-2 (SLC30A2) in the mother. Hormone Research in Paediatrics, 80, 154–155.
11. Bindra GS and Gibson RS, 1986. Mineral intakes of predominantly lacto-ovo vegetarian East Indian adults. Biological Trace Element Research, 10, 223–234.
12. Bjorklund KL, Vahter M, Palm B, Grander M, Lignell S and Berglund M, 2012. Metals and trace element concentrations in breast milk of first time healthy mothers: A biological monitoring study. Environmental Health: A Global Access Science Source, 11.
13. Black RE, 2003. Zinc deficiency, infectious disease and mortality in the developing world. Journal of Nutrition, 133, 1485S–1489S.
14. Brown KH, Engle-Stone R, Krebs NF and Peerson JM, 2009. Dietary intervention strategies to enhance zinc nutrition: promotion and support of breastfeeding for infants and young children. Food and Nutrition Bulletin, 30, S144–171.
15. Brune M, Rossander L and Hallberg L, 1989. Iron absorption: no intestinal adaptation to a high-phytate diet. American Journal of Clinical Nutrition, 49, 542–545.
16. Carnovale E, Lombardi-Boccia G and Lugaro E, 1987. Phytate and zinc content of Italian diets. Human Nutrition. Applied Nutrition, 41, 180–186.
17. Casey CE, Hambidge KM and Neville MC, 1985. Studies in human lactation: zinc, copper, manganese and chromium in human milk in the first month of lactation. American Journal of Clinical Nutrition, 41, 1193–1200.
18. Casey CE, Neville MC and Hambidge KM, 1989. Studies in human lactation: secretion of zinc, copper, and manganese in human milk. American Journal of Clinical Nutrition, 49, 773–785.
19. Cheryan M, 1980. Phytic acid interactions in food systems. Critical Reviews in Food Science and Nutrition, 13, 297–335.
20. Chierici R, Saccomandi D and Vigi V, 1999. Dietary supplements for the lactating mother: influence on the trace element content of milk. Acta Paediatrica. Supplement, 88, 7–13.
21. Chowanadisai W, Lonnerdal B and Kelleher SL, 2006. Identification of a mutation in SLC30A2 (ZnT-2) in women with low milk zinc concentration that results in transient neonatal zinc deficiency. Journal of Biological Chemistry, 281, 39699–39707.
22. Chung CS, Stookey J, Dare D, Welch R, Nguyen TQ, Roehl R, Peerson JM, King JC and Brown KH, 2008. Current dietary zinc intake has a greater effect on fractional zinc absorption than does longer term zinc consumption in healthy adult men. American Journal of Clinical Nutrition, 87, 1224–1229.
23. Coelho S, Fernandes B, Rodrigues F, Reis JP, Moreno A and Figueiredo A, 2006. Transient zinc deficiency in a breast fed, premature infant. European Journal of Dermatology, 16, 193–195.
24. Cohn JR and Emmett EA, 1978. The excretion of trace metals in human sweat. Annals of Clinical and Laboratory Science, 8, 270–275.
25. D-A-CH (Deutsche Gesellschaft für Ernährung, Österreichische Gesellschaft für Ernährung, Schweizerische Gesellschaft für Ernährungsforschung, Schweizerische Vereinigung für Ernährung), 2013. Referenzwerte für die Nährstoffzufuhr. Neuer Umschau Buchverlag, Neustadt an der Weinstraße, Germany, 292 pp.
26. Davidsson L, Mackenzie J, Kastenmayer P, Aggett PJ and Hurrell RF, 1996. Zinc and calcium apparent absorption from an infant cereal: a stable isotope study in healthy infants. British Journal of Nutrition, 75, 291–300.
27. de Benoist B, Darnton-Hill I, Davidsson L, Fontaine O and Hotz C, 2007. Conclusions of the Joint WHO/UNICEF/IAEA/IZiNCG Interagency Meeting on Zinc Status Indicators. Food and Nutrition Bulletin, 28, S480–484.
28. DeRuisseau KC, Cheuvront SN, Haymes EM and Sharp RG, 2002. Sweat iron and zinc losses during prolonged exercise. International Journal of Sport Nutrition and Exercise Metabolism, 12, 428–437.
29. DH (Department of Health), 1991. Dietary reference values for food energy and nutrients for the United Kingdom. Report of the Panel on Dietary Reference Values of the Committee on Medical Aspects of Food Policy. HM Stationary Office, London, UK, 212 pp.
30. Domellof M, Hernell O, Dewey KG, Cohen RJ and Lonnerdal B, 2004. Factors influencing concentrations of iron, zinc, and copper in human milk. Advances in Experimental Medicine and Biology, 554, 355–358.
31. Donangelo CM, Zapata CL, Woodhouse LR, Shames DM, Mukherjea R and King JC, 2005. Zinc absorption and kinetics during pregnancy and lactation in Brazilian women. American Journal of Clinical Nutrition, 82, 118–124.
32. Donangelo CM and King JC, 2012. Maternal zinc intakes and homeostatic adjustments during pregnancy and lactation. Nutrients, 4, 782–798.
33. EFSA (European Food Safety Authority), 2011a. Report on the development of a food classification and description system for exposure assessment and guidance on its implementation and use. EFSA Journal 2011;9(12):2489, 84 pp. doi:10.2903/j.efsa.2011.2489.
34. EFSA (European Food Safety Authority), 2011b. Use of the EFSA Comprehensive European Food Consumption Database in Exposure Assessment. EFSA Journal 2011;9(3):2097, 34 pp. doi:10.2903/j.efsa.2011.2097.
35. EFSA NDA Panel (EFSA Panel on Dietetic Products Nutrition and Allergies), 2012. Scientific Opinion on Dietary Reference Values for protein. EFSA Journal 2012;10(2):2557, 66 pp. doi:10.2903/j.efsa.2012.2557.
36. EFSA NDA Panel (EFSA Panel on Dietetic Products, Nutrition and Allergies), 2013. Scientific Opinion on Dietary Reference Values for energy. EFSA Journal 2013;11(1):3005, 112 pp. doi:10.2903/j.efsa.2013.3005.
37. Ellis R, Kelsay JL, Reynolds RD, Morris ER, Moser PB and Frazier CW, 1987. Phytate:zinc and phytate X calcium:zinc millimolar ratios in self-selected diets of Americans, Asian Indians, and Nepalese. Journal of the American Dietetic Association, 87, 1043–1047.
38. Elmastas M, Can M, Uzun S and Aboul-Enein HY, 2005. Determinations of copper, zinc, cadmium, and nickel in cows', goats', ewes', and human milk samples using flame atomic absorption spectrometry (FAAS) microwave digestion. Analytical Letters, 38, 157–165.
39. Fairweather-Tait SJ, Wharf SG and Fox TE, 1995. Zinc absorption in infants fed iron-fortified weaning food. American Journal of Clinical Nutrition, 62, 785–789.
40. Frye AJ and Kamon E, 1983. Sweating efficiency in acclimated men and women exercising in humid and dry heat. Journal of Applied Physiology: Respiratory, Environmental and Exercise Physiology, 54, 972–977.
41. Fung EB, Ritchie LD, Woodhouse LR, Roehl R and King JC, 1997. Zinc absorption in women during pregnancy and lactation: a longitudinal study. American Journal of Clinical Nutrition, 66, 80–88.
42. Gass JK, Hafiji J and Burrows NP, 2010. Acrodermatitis due to zinc-deficient breast milk. British Journal of Dermatology, 162, 1164–1165.
43. Gehan EA and George SL, 1970. Estimation of human body surface area from height and weight. Cancer Chemotherapy reports. Part 1, 54, 225–235.
44. Gibson RS, Vanderkooy PD, MacDonald AC, Goldman A, Ryan BA and Berry M, 1989. A growth-limiting, mild zinc-deficiency syndrome in some southern Ontario boys with low height percentiles. American Journal of Clinical Nutrition, 49, 1266–1273.
45. Gibson RS, Heywood A, Yaman C, Sohlstrom A, Thompson LU and Heywood P, 1991. Growth in children from the Wosera subdistrict, Papua New Guinea, in relation to energy and protein intakes and zinc status. American Journal of Clinical Nutrition, 53, 782–789.
46. Gibson RS, Heath AL, Prosser N, Parnell W, Donovan UM, Green T, McLaughlin KE, O'Connor DL, Bettger W and Skeaff CM, 2000. Are young women with low iron stores at risk of zinc as well as iron deficiency? In: Trace Elements in Man and Animals. Eds Roussel AM, Anderson RA and Favrier A. Kluwer Academic, New York, USA, 323–328.
47. Grider A, Bailey LB and Cousins RJ, 1990. Erythrocyte metallothionein as an index of zinc status in humans. Proceedings of the National Academy of Sciences of the United States of America, 87, 1259–1262.
48. Griffin IJ, Hicks PD, Liang LK and Abrams SA, 2004. Metabolic adaptations to low zinc intakes in premenarcheal girls. American Journal of Clinical Nutrition, 80, 385–390.
49. Griffin IJ, Lynch MF, Hawthorne KM, Chen Z, Hamzo MG and Abrams SA, 2007. Zinc homeostasis in 1–4 year olds consuming diets typical of US children. British Journal of Nutrition, 98, 358–363.
50. Guo L, Lichten LA, Ryu MS, Liuzzi JP, Wang F and Cousins RJ, 2010. STAT5-glucocorticoid receptor interaction and MTF-1 regulate the expression of ZnT2 (Slc30a2) in pancreatic acinar cells. Proceedings of the National Academy of Sciences of the United States of America, 107, 2818–2823.
51. Hambidge K, Casey C and Krebs N, 1986. Zinc. In: Human and animal nutrition. Ed Mertz W. Academic Press, New York, USA, 1–137.
52. Hambidge KM, Hambidge C, Jacobs M and Baum JD, 1972. Low levels of zinc in hair, anorexia, poor growth, and hypogeusia in children. Pediatric Research, 6, 868–874.
53. Hambidge KM, Huffer JW, Raboy V, Grunwald GK, Westcott JL, Sian L, Miller LV, Dorsch JA and Krebs NF, 2004. Zinc absorption from low-phytate hybrids of maize and their wild-type isohybrids. American Journal of Clinical Nutrition, 79, 1053–1059.
54. Hambidge KM, Miller LV, Tran CD and Krebs NF, 2005. Measurements of zinc absorption: application and interpretation in research designed to improve human zinc nutriture. International Journal for Vitamin and Nutrition Research, 75, 385–393.
55. Hambidge KM, Miller LV, Westcott JE, Sheng X and Krebs NF, 2010. Zinc bioavailability and homeostasis. American Journal of Clinical Nutrition, 91, 1478S–1483S.
56. Harland BF and Oberleas D, 1977. A modified method for phytate analysis using an ion exchange procedure: application to textured vegetable proteins. Cereal Chem, 54, 827–832.
57. Harland BF and Oberleas D, 1986. Anion-exchange method for determination of phytate in foods: collaborative study. Journal of the Association of Official Analytical Chemists, 69, 667–670.
58. Harvey LJ, Dainty JR, Hollands WJ, Bull VJ, Hoogewerff JA, Foxall RJ, McAnena L, Strain JJ and Fairweather-Tait SJ, 2007. Effect of high-dose iron supplements on fractional zinc absorption and status in pregnant women. American Journal of Clinical Nutrition, 85, 131–136.
59. Hazelhurst LT and Claassen N, 2006. Gender differences in the sweat response during spinning exercise. Journal of Strength and Conditioning Research, 20, 723–724.
60. Heath AL, Roe MA, Oyston SL and Fairweather-Tait SJ, 2005. Meal-based intake assessment tool: relative validity when determining dietary intake of Fe and Zn and selected absorption modifiers in UK men. British Journal of Nutrition, 93, 403–416.
61. Hedera P, Peltier A, Fink JK, Wilcock S, London Z and Brewer GJ, 2009. Myelopolyneuropathy and pancytopenia due to copper deficiency and high zinc levels of unknown origin II. The denture cream is a primary source of excessive zinc. Neurotoxicology, 30, 996–999.
62. Helldán A, Raulio S, Kosola M, Tapanainen H, Ovaskainen ML and Virtanen S, 2013. Finravinto 2012 -tutkimus – The National FINDIET 2012 Survey. THL. Raportti 16/2013, 217 pp.
63. Hess FM, King JC and Margen S, 1977. Zinc excretion in young women on low zinc intakes and oral contraceptive agents. Journal of Nutrition, 107, 1610–1620.
64. Hoppu U, Lehtisalo J, Tapanainen H and Pietinen P, 2010. Dietary habits and nutrient intake of Finnish adolescents. Public Health Nutrition, 13, 965–972.
65. Hunt CD, Johnson PE, Herbel J and Mullen LK, 1992. Effects of dietary zinc depletion on seminal volume and zinc loss, serum testosterone concentrations, and sperm morphology in young men. American Journal of Clinical Nutrition, 56, 148–157.
66. Hunt J, Mullen L and Lykken G, 1992. Zinc retention from an experimental diet based on the FDA Total Diet Study. Nutrition Research, 1335–1344.
67. Hunt JR, Gallagher SK, Johnson LK and Lykken GI, 1995. High- versus low-meat diets: effects on zinc absorption, iron status, and calcium, copper, iron, magnesium, manganese, nitrogen, phosphorus, and zinc balance in postmenopausal women. American Journal of Clinical Nutrition, 62, 621–632.
68. Hunt JR, Matthys LA and Johnson LK, 1998. Zinc absorption, mineral balance, and blood lipids in women consuming controlled lactoovovegetarian and omnivorous diets for 8 wk. American Journal of Clinical Nutrition, 67, 421–430.
69. Hunt JR, Beiseigel JM and Johnson LK, 2008. Adaptation in human zinc absorption as influenced by dietary zinc and bioavailability. American Journal of Clinical Nutrition, 87, 1336–1345.
70. Hunt JR and Beiseigel JM, 2009. Dietary calcium does not exacerbate phytate inhibition of zinc absorption by women from conventional diets. American Journal of Clinical Nutrition, 89, 839–843.
71. Hytten FE, 1980. Weight gain in pregnancy. In: Clinical Physiology in Obstetrics. Part 2. Nutrition and Metabolism. Eds Hytten FE and Chamberlain G. Blackwell Scientific Publications, Oxford, UK, 193–233.
72. Ingelmann H-J, Rimbach G and Pallauf J, 1993. Phytinsäure – ein antinutritiver Faktor? Ernährungs-Umschau, 40, 400–404.
73. IOM (Institute of Medicine), 2001. Dietary Reference Intakes for vitamin A, vitamin K, arsenic, boron, chromium, copper, iodine, iron, manganese, molybdenum, nickel, silicon, vanadium and zinc. National Academies Press, Washington DC, USA, 797 pp.
74. IUNA (Irish Universities Nutrition Alliance), 2011. National Adult Nutrition Survey. 40 pp.
75. Jackson MJ, Jones DA, Edwards RH, Swainbank IG and Coleman ML, 1984. Zinc homeostasis in man: studies using a new stable isotope-dilution technique. British Journal of Nutrition, 51, 199–208.
76. Jacob RA, Sandstead HH, Munoz JM, Klevay LM and Milne DB, 1981. Whole body surface loss of trace metals in normal males. American Journal of Clinical Nutrition, 34, 1379–1383.
77. Johnson PE, Hunt CD, Milne DB and Mullen LK, 1993. Homeostatic control of zinc metabolism in men: zinc excretion and balance in men fed diets low in zinc. American Journal of Clinical Nutrition, 57, 557–565.
78. Kantola M and Vartiainen T, 2001. Changes in selenium, zinc, copper and cadmium contents in human milk during the time when selenium has been supplemented to fertilizers in Finland. Journal of Trace Elements in Medicine and Biology, 15, 11–17.
79. Kersting M and Clausen K, 2003. Ernährungsphysiologische Auswertung einer repräsentativen Verzehrsstudie bei Säuglingen und Kleinkindern VELS mit dem Instrumentarium der DONALD Studie. Forschungsinstitut für Kinderernährung, Dortmund, Germany, 103 pp.
80. Kettunen J, Tukiainen T, Sarin AP, Ortega-Alonso A, Tikkanen E, Lyytikainen LP, Kangas AJ, Soininen P, Wurtz P, Silander K, Dick DM, Rose RJ, Savolainen MJ, Viikari J, Kahonen M, Lehtimaki T, Pietilainen KH, Inouye M, McCarthy MI, Jula A, Eriksson J, Raitakari OT, Salomaa V, Kaprio J, Jarvelin MR, Peltonen L, Perola M, Freimer NB, Ala-Korpela M, Palotie A and Ripatti S, 2012. Genome-wide association study identifies multiple loci influencing human serum metabolite levels. Nature Genetics, 44, 269–276.
81. Kharfi M, Zaraa I, Kury S, Moisan JP and Kamoun MR, 2005. [Acrodermatitis enteropathica in full-term breast-fed infant]. Annales de Dermatologie et de Vénéréologie, 132, 246–248.
82. Khokhar S and Pushpanjali, 1994. Phytate content of Indian foods and intakes by vegetarian Indians of Hisar Region, Haryana State. Journal of Agricultural and Food Chemistry, 42, 2440–2444.
83. Kim J, Paik HY, Joung H, Woodhouse LR, Li S and King JC, 2007. Effect of dietary phytate on zinc homeostasis in young and elderly Korean women. Journal of the American College of Nutrition, 26, 1–9.
84. King JC and Turnlund JR, 1989. Human zinc requirements. In: Zinc in Human Biology. Ed Mills C. Springer Verlag, London, UK, 335–350.
85. King JC, 2000. Determinants of maternal zinc status during pregnancy. American Journal of Clinical Nutrition, 71, 1334S–1343S.
86. King JC, Shames DM, Lowe NM, Woodhouse LR, Sutherland B, Abrams SA, Turnlund JR and Jackson MJ, 2001. Effect of acute zinc depletion on zinc homeostasis and plasma zinc kinetics in men. American Journal of Clinical Nutrition, 74, 116–124.
87. King JC, 2011. Zinc: an essential but elusive nutrient. American Journal of Clinical Nutrition, 94, 679S–684S.
88. King JC and Cousins R, 2014. Zinc. In: Modern Nutrition in Health and Disease. Eds Ross AC, Caballero B, Cousins RJ, Tucker KL and Ziegler TR. Lippincott Williams & Wilkins, Philadelphia, USA, 189–205.
89. Kirchgessner M, Sporl R and Roth-Maier DA, 1980. [Fecal excretion and apparent absorption of copper, zinc nickel and manganese in nonpregnant and pregnant sows with differing dietary supplies of trace elements]. Zeitschrift für Tierphysiologie, Tierernährung und Futtermittelkunde, 44, 98–111.
90. Knudsen E, Sandstrom B and Solgaard P, 1996. Zinc, copper and magnesium absorption from a fibre-rich diet. Journal of Trace Elements in Medicine and Biology, 10, 68–76.
91. Krebs NF and Hambidge KM, 1986. Zinc requirements and zinc intakes of breast-fed infants. American Journal of Clinical Nutrition, 43, 288–292.
92. Krebs NF, 1993. Zinc absorption and fecal excretion of endogenous zinc in the breastfed infant. In: Trace elements in man and animals – Tema 8. Ed Anke M. Media Verlag Toursitik, Dresden, Germany, 1110–1113.
93. Krebs NF, Reidinger CJ, Hartley S, Robertson AD and Hambidge KM, 1995. Zinc supplementation during lactation: effects on maternal status and milk zinc concentrations. American Journal of Clinical Nutrition, 61, 1030–1036.
94. Krebs NF, Reidinger CJ, Miller LV and Hambidge KM, 1996. Zinc homeostasis in breast-fed infants. Pediatric Research, 39, 661–665.
95. Krezel A, Hao Q and Maret W, 2007. The zinc/thiolate redox biochemistry of metallothionein and the control of zinc ion fluctuations in cell signaling. Archives of Biochemistry and Biophysics, 463, 188–200.
96. Kristensen MB, Hels O, Morberg CM, Marving J, Bugel S and Tetens I, 2006. Total zinc absorption in young women, but not fractional zinc absorption, differs between vegetarian and meat-based diets with equal phytic acid content. British Journal of Nutrition, 95, 963–967.
97. Kuczmarski RJ, Ogden CL, Grummer-Strawn LM, Flegal KM, Guo SS, Wei R, Mei Z, Curtin LR, Roche AF and Johnson CL (National Center for Health Statistics), 2000. CDC Growth Charts: United States. Advance data from vital health statistics. No. 314. 28 pp.
98. Kyttälä P, Ovaskainen M, Kronberg-Kippilä C, Erkkola M, Tapanainen H, Tuokkola J, Veijola R, Simell O, Knip M and Virtanen S, 2008. The Diet of Finnish Preschoolers (in Finnish, abstract in English). Publications of the National Public Health Institute B32/2008, 154 pp.
99. Kyttälä P, Erkkola M, Kronberg-Kippila C, Tapanainen H, Veijola R, Simell O, Knip M and Virtanen SM, 2010. Food consumption and nutrient intake in Finnish 1–6-year-old children. Public Health Nutrition, 13, 947–956.
100. Lee DY, Prasad AS, Hydrick-Adair C, Brewer G and Johnson PE, 1993. Homeostasis of zinc in marginal human zinc deficiency: role of absorption and endogenous excretion of zinc. Journal of Laboratory and Clinical Medicine, 122, 549–556.
101. Lentner C, 1984. Geigy scientific tables, Vol. 3. Body composition during pregnancy. CIBA-Geigy, Basel, Switzeland, 359 pp.
102. Leotsinidis M, Alexopoulos A and Kostopoulou-Farri E, 2005. Toxic and essential trace elements in human milk from Greek lactating women: Association with dietary habits and other factors. Chemosphere, 61, 238–247.
103. Leverkus M, Kutt S, Brocker EB, Frank J and Hamm H, 2006. Nutritional zinc deficiency mimicking acrodermatitis enteropathica in a fully breast-fed infant. Journal of the European Academy of Dermatology and Venereology, 20, 1380–1381.
104. Lopez de Romana D, Salazar M, Hambidge KM, Penny ME, Peerson JM, Krebs NF and Brown KH, 2005. Longitudinal measurements of zinc absorption in Peruvian children consuming wheat products fortified with iron only or iron and 1 of 2 amounts of zinc. American Journal of Clinical Nutrition, 81, 637–647.
105. Lowe NM, Shames DM, Woodhouse LR, Matel JS, Roehl R, Saccomani MP, Toffolo G, Cobelli C and King JC, 1997. A compartmental model of zinc metabolism in healthy women using oral and intravenous stable isotope tracers. American Journal of Clinical Nutrition, 65, 1810–1819.
106. Lowe NM, Fekete K and Decsi T, 2009. Methods of assessment of zinc status in humans: a systematic review. American Journal of Clinical Nutrition, 89, 2040S–2051S.
107. Lowe NM, Dykes FC, Skinner AL, Patel S, Warthon-Medina M, Decsi T, Fekete K, Souverein OW, Dullemeijer C, Cavelaars AE, Serra-Majem L, Nissensohn M, Bel S, Moreno LA, Hermoso M, Vollhardt C, Berti C, Cetin I, Gurinovic M, Novakovic R, Harvey LJ, Collings R and Hall-Moran V, 2013. EURRECA-Estimating zinc requirements for deriving dietary reference values. Critical Reviews in Food Science and Nutrition, 53, 1110–1123.
108. Mahomed K, James DK, Golding J and McCabe R, 1989. Zinc supplementation during pregnancy: a double blind randomised controlled trial. British Medical Journal (Clinical Research Edition), 299, 826–830.
109. Manary MJ, Hotz C, Krebs NF, Gibson RS, Westcott JE, Arnold T, Broadhead RL and Hambidge KM, 2000. Dietary phytate reduction improves zinc absorption in Malawian children recovering from tuberculosis but not in well children. Journal of Nutrition, 130, 2959–2964.
110. Mandato F, Rubegni P, Buonocore G and Fimiani M, 2009. A case of transient zinc deficiency in a breast-fed preterm infant successfully treated with oral zinc supplementation: Review of zinc methabolism and related diseases. Giornale Italiano di Dermatologia e Venereologia, 144, 729–734.
111. Matos C, Moutinho C, Balcao V, Almeida C, Ribeiro M, Marques A and Guerra A, 2009. Total antioxidant activity and trace elements in human milk: the first 4 months of breast-feeding. European Food Research and Technology, 230, 201–208.
112. Mazariegos M, Hambidge KM, Krebs NF, Westcott JE, Lei S, Grunwald GK, Campos R, Barahona B, Raboy V and Solomons NW, 2006. Zinc absorption in Guatemalan schoolchildren fed normal or low-phytate maize. American Journal of Clinical Nutrition, 83, 59–64.
113. Mensink GB, Heseker H, Richter A, Stahl A and Vohmann C (Robert Koch-Institut & Universität Paderborn), 2007. Ernährungsstudie als KIGGS-Modul (EsKiMo). 143 pp.
114. Milacic R, Ajlec D, Zuliani T, Zigon D and Scancar J, 2012. Determination of Zn-citrate in human milk by CIM monolithic chromatography with atomic and mass spectrometry detection. Talanta, 101, 203–210.
115. Miletta MC, Bieri A, Kernland K, Schoni MH, Petkovic V, Fluck CE, Eble A and Mullis PE, 2013. Transient neonatal zinc deficiency caused by a heterozygous G87R mutation in the zinc transporter ZnT-2 (SLC30A2) gene in the mother highlighting the importance of Zn (2+) for normal growth and development. International Journal of Endocrinology, 2013, 259189.
116. Miller LV, Krebs NF and Hambidge KM, 1998. Human zinc metabolism: advances in the modeling of stable isotope data. Advances in Experimental Medicine and Biology, 445, 253–269.
117. Miller LV, Krebs NF and Hambidge KM, 2000. Development of a compartmental model of human zinc metabolism: identifiability and multiple studies analyses. American Journal of Physiology – Regulatory, Integrative and Comparative Physiology, 279, R1671–1684.
118. Miller LV, Krebs NF and Hambidge KM, 2007. A mathematical model of zinc absorption in humans as a function of dietary zinc and phytate. Journal of Nutrition, 137, 135–141.
119. Mills C, 1989. Zinc in Human Biology. Springer, London, UK, 388 pp.
120. Milne DB, Canfield WK, Mahalko JR and Sandstead HH, 1983. Effect of dietary zinc on whole body surface loss of zinc: impact on estimation of zinc retention by balance method. American Journal of Clinical Nutrition, 38, 181–186.
121. Milne DB, Canfield WK, Gallagher SK, Hunt JR and Klevay LM, 1987. Ethanol metabolism in postmenopausal women fed a diet marginal in zinc. American Journal of Clinical Nutrition, 46, 688–693.
122. Morgan PH, Mercer LP and Flodin NW, 1975. General model for nutritional responses of higher organisms. Proceedings of the National Academy of Sciences of the United States of America, 72, 4327–4331.
123. Moser-Veillon PB and Reynolds RD, 1990. A longitudinal study of pyridoxine and zinc supplementation of lactating women. American Journal of Clinical Nutrition, 52, 135–141.
124. Moser-Veillon PB, 1995. Zinc needs and homeostasis during lactation. Analyst, 120, 895–897.
125. Netherlands Food and Nutrition Council, 1992. Recommended dietary allowances 1989 in The Netherlands. The Hague, The Netherlands, 115 pp.
126. NNR (Nordic Nutrition Recommendations), 2004. Integrating nutrition and physical activity. Nordic Council of Ministers, Copenhagen, Denmark, 435 pp.
127. Nordic Council of Ministers, 2014. Nordic Nutrition Recommendations 2012. Integrating nutrition and physical activity. 5th edition. Nordic Council of Ministers, Copenhagen, Denmark, 627 pp.
128. Ortega RM, Andres P, Martinez RM, Lopez-Sobaler AM and Quintas ME, 1997. Zinc levels in maternal milk: the influence of nutritional status with respect to zinc during the third trimester of pregnancy. European Journal of Clinical Nutrition, 51, 253–258.
129. Perrone L, Di Palma L, Di Toro R, Gialanella G and Moro R, 1993. Trace element content of human milk during lactation. Journal of Trace Elements and Electrolytes in Health and Disease, 7, 245–247.
130. Perrone L, Dipalma L, Ditoro R, Gialanella G and Moro R, 1994. Interaction of trace elements in a longitudinal study of human milk from full-term and preterm mothers. Biological Trace Element Research, 41, 321–330.
131. Pinna K, 1999. Effect of a low zinc intake on zinc homeostasis and immune function in adult men [doctoral dissertation]. University of California, Berkeley, CA, USA.
132. Pinna K, Woodhouse LR, Sutherland B, Shames DM and King JC, 2001. Exchangeable zinc pool masses and turnover are maintained in healthy men with low zinc intakes. Journal of Nutrition, 131, 2288–2294.
133. Piotrowska-Dept MJ, Piotrowska-Jastrzebska J, Borawska M, Markiewicz R, Socha K and Malinowska A, 2006. Zinc concentration in breast-milk of women living in Podlasie. Pediatria Wspolczesna Zawartosc cynku w mleku kobiet karmiacych piersia zamieszkalych na terenie Podlasia, 2006, 121–125.
134. Plaami S and Kumpulainen J, 1996. Trace elements, natural antioxidants and contaminants in European foods and diets. Proceedings of a Technical Workshop on Trace Elements, Natural Antioxidants and Contaminants. Helsinki (Finland), 25–26 Aug 1995. REU Technical Series (FAO). 1020–3737, no. 49, 169–185.
135. Prynne CJ, McCarron A, Wadsworth ME and Stephen AM, 2010. Dietary fibre and phytate-a balancing act: results from three time points in a British birth cohort. British Journal of Nutrition, 103, 274–280.
136. Rodriguez Rodriguez EM, Sanz Alaejos M and Diaz Romero C, 2000. Concentrations of iron, copper and zinc in human milk and powdered infant formula. International Journal of Food Sciences and Nutrition, 51, 373–380.
137. Roe MA, Bell S, Oseredczuk M, Christensen T, Westenbrink S, Pakkala H, Presser K and Finglas PM, 2013. Updated food composition database for nutrient intake EFSA supporting publication 2013:EN-355, 21 pp.
138. Rosado JL, Hambidge KM, Miller LV, Garcia OP, Westcott J, Gonzalez K, Conde J, Hotz C, Pfeiffer W, Ortiz-Monasterio I and Krebs NF, 2009. The quantity of zinc absorbed from wheat in adult women is enhanced by biofortification. Journal of Nutrition, 139, 1920–1925.
139. Ruz M, 1984. Recommended zinc intake for the first six months of life. Nutrition Research, 4, 923–927.
140. Ryu MS, Guthrie GJ, Maki AB, Aydemir TB and Cousins RJ, 2012. Proteomic analysis shows the upregulation of erythrocyte dematin in zinc-restricted human subjects. American Journal of Clinical Nutrition, 95, 1096–1102.
141. Salmenpera L, Perheentupa J, Nanto V and Siimes MA, 1994. Low zinc intake during exclusive breast-feeding does not impair growth. Journal of Pediatric Gastroenterology and Nutrition, 18, 361–370.
142. Sandstead HH, 1973. Zinc nutrition in the United States. American Journal of Clinical Nutrition, 26, 1251–1260.
143. Sandstrom B, Bugel S, McGaw BA, Price J and Reid MD, 2000. A high oat-bran intake does not impair zinc absorption in humans when added to a low-fiber animal protein-based diet. Journal of Nutrition, 130, 594–599.
144. SCF (Scientific Committee for Food), 1993. Nutrient and energy intakes for the European Community. Reports of the Scientific Committee for Food, 31st series. Food – Science and Techniques. Scientific Committee for Food, Luxembourg, European Commission, 248 pp.
145. SCF (Scientific Committee on Food), 2002. Opinion of the Scientific Committee on Food on the Tolerable Upper Intake Level of zinc (expressed on 5 March 2002). SCF/CS/NUT/UPPLEV/62 Final, 18 pp.
146. Schlemmer U, 1995. Phytinsäuren und Phytasen in der Human- und Tierernährung. In: 5th Symposium Vitamine und Zusatzstoffe in der Ernährung von Mensch und Tier, Friedrich-Schiller-Universität. Eds Schubert R, Flachowsky G and Bitsch R. Jena, Germany, 354–365.
147. Schlemmer U, Frolich W, Prieto RM and Grases F, 2009. Phytate in foods and significance for humans: food sources, intake, processing, bioavailability, protective role and analysis. Molecular Nutrition & Food Research, 53 Suppl 2, S330–375.
148. Sette S, Le Donne C, Piccinelli R, Arcella D, Turrini A and Leclercq C, 2011. The third Italian National Food Consumption Survey, INRAN-SCAI 2005–06 – Part 1: Nutrient intakes in Italy. Nutrition, Metabolism and Cardiovascular Diseases, 21, 922–932.
149. Shaw JC, 1979. Trace elements in the fetus and young infant. I. Zinc. American Journal of Diseases of Children, 133, 1260–1268.
150. Sheng XY, Hambidge KM, Zhu XX, Ni JX, Bailey KB, Gibson RS and Krebs NF, 2006. Major variables of zinc homeostasis in Chinese toddlers. American Journal of Clinical Nutrition, 84, 389–394.
151. Sheng XY, Hambidge KM, Miller LV, Westcott JE, Lei S and Krebs NF, 2009. Measurement of zinc absorption from meals: comparison of extrinsic zinc labeling and independent measurements of dietary zinc absorption. International Journal for Vitamin and Nutrition Research, 79, 230–237.
152. Sian L, Mingyan X, Miller LV, Tong L, Krebs NF and Hambidge KM, 1996. Zinc absorption and intestinal losses of endogenous zinc in young Chinese women with marginal zinc intakes. American Journal of Clinical Nutrition, 63, 348–353.
153. Sievers E, Oldigs HD, Dorner K and Schaub J, 1992. Longitudinal zinc balances in breast-fed and formula-fed infants. Acta Paediatrica, 81, 1–6.
154. Sievers E and Schaub J, 2004. Zinc concentration in human milk: Longitudinal studies in consecutive lactation periods. Advances in Experimental Medicine and Biology, 554, 403–405.
155. Silvestre D, Martinez-Costa C, Lagarda MJ, Brines J, Farre R and Clemente G, 2001. Copper, iron, and zinc contents in human milk during the first three months of lactation: A longitudinal study. Biological Trace Element Research, 80, 1–11.
156. Silvestre MD, Lagarda MJ, Farre R, Martinez-Costa C and Brines J, 2000a. Copper, iron and zinc determinations in human milk using FAAS with microwave digestion. Food Chemistry, 68, 95–99.
157. Silvestre MD, Lagarda MJ, Farre R, Martinez-Costa C, Brines J, Molina A and Clemente G, 2000b. A study of factors that may influence the determination of copper, iron, and zinc in human milk during sampling and in sample individuals. Biological Trace Element Research, 76, 217–227.
158. Stawarz R, Formicki G and Massanyi P, 2007. Daily fluctuations and distribution of xenobiotics, nutritional and biogenic elements in human milk in Southern Poland. Journal of Environmental Science and Health – Part A Toxic/Hazardous Substances and Environmental Engineering, 42, 1169–1175.
159. Swanson CA and King JC, 1982. Zinc utilization in pregnant and nonpregnant women fed controlled diets providing the zinc RDA. Journal of Nutrition, 112, 697–707.
160. Swanson CA and King JC, 1987. Zinc and pregnancy outcome. American Journal of Clinical Nutrition, 46, 763–771.
161. Taylor CM, Bacon JR, Aggett PJ and Bremner I, 1991. Homeostatic regulation of zinc absorption and endogenous losses in zinc-deprived men. American Journal of Clinical Nutrition, 53, 755–763.
162. Tipton K, Green NR, Haymes EM and Waller M, 1993. Zinc loss in sweat of athletes exercising in hot and neutral temperatures. International Journal of Sport Nutrition, 3, 261–271.
163. Torelm I and Bruce A, 1982. Fytinsyra i livesmedel. Var Foda, 34, 79–96.
164. Turnlund JR, King JC, Keyes WR, Gong B and Michel MC, 1984. A stable isotope study of zinc absorption in young men: effects of phytate and alpha-cellulose. American Journal of Clinical Nutrition, 40, 1071–1077.
165. Turnlund JR, Durkin N, Costa F and Margen S, 1986. Stable isotope studies of zinc absorption and retention in young and elderly men. Journal of Nutrition, 116, 1239–1247.
166. Turnlund JR, Keyes WR, Hudson CA, Betschart AA, Kretsch MJ and Sauberlich HE, 1991. A stable-isotope study of zinc, copper, and iron absorption and retention by young women fed vitamin B-6-deficient diets. American Journal of Clinical Nutrition, 54, 1059–1064.
167. Ustundag B, Yilmaz E, Dogan Y, Akarsu S, Canatan H, Halifeoglu I, Cikim G and Denizmen Aygun A, 2005. Levels of cytokines (IL-1(beta), IL-2, IL-6, IL-8, TNF-(alpha)) and trace elements (Zn, Cu) in breast milk from mothers of preterm and term infants. Mediators of Inflammation, 2005, 331–336.
168. Van't Hof MA, Haschke F and Darvay S, 2000. Euro-Growth references on increments in length, weight, and head and arm circumferences during the first 3 years of life. Euro-Growth Study Group. Journal of Pediatric Gastroenterology and Nutrition, 31 Suppl 1, S39–47.
169. Van Buuren S, Schönbeck Y and Van Dommelen P, 2012. Collection, collation and analysis of data in relation to reference heights and reference weights for female and male children and adolescents (0–18 years) in the EU, as well as in relation to the age of onset of puberty and the age at which different stages of puberty are reached in adolescents in the EU. Project developed on the procurement project CT/EFSA/NDA/2010/01. EFSA supporting publication 2012:EN-255, 59 pp.
170. Van Rossum CTM, Fransen HP, Verkaik-Kloosterman J, Buurma-Rethans EJM and Ocké MC, 2011. Dutch National Food Consumption Survey 2007–2010: Diet of children and adults aged 7 to 69 years. RIVM Report number: 350050006/2011, National Institute for Public Health and the Environment, 143 pp.
171. Vuori E, 1979a. Copper, iron, manganese and zinc in breast milk. University of Helsinki, Helsinki, Finland, 40 pp.
172. Vuori E, 1979b. Intake of copper, iron, manganese and zinc by healthy, exclusively-breast-fed infants during the first 3 months of life. British Journal of Nutrition, 42, 407–411.
173. Vuori E, Makinen SM, Kara R and Kuitunen P, 1980. The effects of the dietary intakes of copper, iron, manganese, and zinc on the trace element content of human milk. American Journal of Clinical Nutrition, 33, 227–231.
174. Wada L, Turnlund JR and King JC, 1985. Zinc utilization in young men fed adequate and low zinc intakes. Journal of Nutrition, 115, 1345–1354.
175. Wada L and King JC, 1986. Effect of low zinc intakes on basal metabolic rate, thyroid hormones and protein utilization in adult men. Journal of Nutrition, 116, 1045–1053.
176. Walravens PA, Krebs NF and Hambidge KM, 1983. Linear growth of low income preschool children receiving a zinc supplement. American Journal of Clinical Nutrition, 38, 195–201.
177. Walravens PA, Hambidge KM and Koepfer DM, 1989. Zinc supplementation in infants with a nutritional pattern of failure to thrive: a double-blind, controlled study. Pediatrics, 83, 532–538.
178. Wasowicz W, Gromadzinska J, Szram K, Rydzynski K, Cieslak J and Pietrzak Z, 2001. Selenium, zinc, and copper concentrations in the blood and milk of lactating women. Biological Trace Element Research, 79, 221–233.
179. Wastney ME, Aamodt RL, Rumble WF and Henkin RI, 1986. Kinetic analysis of zinc metabolism and its regulation in normal humans. American Journal of Physiology, 251, R398–408.
180. Weigand E and Kirchgessner M, 1982. Factorial estimation of the zinc requirement of lactating dairy cows. Zeitschrift für Tierphysiologie, Tierernährung und Futtermittelkunde, 47, 1–9.
181. Weigand E and Kirchgessner M, 1992. Absorption, endogenous excretion, and balance of zinc in growing rats on diets with various sugars replacing starch. Biological Trace Element Research, 34, 67–77.
182. Wessells KR, King JC and Brown KH, 2014. Development of a plasma zinc concentration cutoff to identify individuals with severe zinc deficiency based on results from adults undergoing experimental severe dietary zinc restriction and individuals with acrodermatitis enteropathica. Journal of Nutrition, 144, 1204–1210.
183. WHO (World Health Organization), 1973. Trace elements in human nutrition. WHO Technical Report Series 532. 64 pp.
184. WHO (World Health Organization), 1996. Trace elements in human nutrition and health. 343 pp.
185. WHO Multicentre Growth Reference Study Group (World Health Organization), 2006. WHO Child Growth Standards: Length/height-for-age, weight-for-age, weight-for-length, weight-for-height and body mass index-for-age: Methods and development. 312 pp.
186. WHO/FAO (World Health Organization/Food and Agriculture Organization of the United Nations), 2004. Vitamin and mineral requirements in human nutrition. Report of a joint FAO/WHO expert consultation, Bangkok, Thailand, 21–30 September 1998. 341 pp.
187. Widdowson EM and Spray CM, 1951. Chemical development in utero. Archives of Disease in Childhood, 26, 205–214.
188. Widdowson EM and Dickerson JWT, 1964. Chemical composition of the body. In: Mineral Metabolism. An Advanced Treatise, Vol. II. The elements. Part A. Eds Comar CL and Bronner F. Academic Press, New York, USA, p 26.
189. Yalcin SS, Baykan A, Yurdakok K, Yalcn S and Gucus AI, 2009. The factors that affect milk-to-serum ratio for iron during early lactation. Journal of Pediatric Hematology/Oncology, 31, 85–90.
190. Younoszai HD, 1983. Clinical zinc deficiency in total parenteral nutrition: zinc supplementation. Journal of Parenteral and Enteral Nutrition, 7, 72–74.