Zinc: An essential but elusive nutrient

American Journal of Clinical Nutrition

Volumn 94, Issue 2, 2011, Pages

  King, Janet C ^a  

^a CHILDREN S HOSPITAL OAKLAND RESEARCH INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

METALLOTHIONEIN; ZINC;

CELL ORGANELLE; GOLGI COMPLEX; HOMEOSTASIS; HUMAN; NONHUMAN; REVIEW; ZINC BLOOD LEVEL; ZINC DEFICIENCY;

BIOLOGICAL MARKERS; HOMEOSTASIS; HUMANS; METALLOTHIONEIN; NUTRITIONAL STATUS; ZINC;

EID: 79960880727     PISSN: 00029165     EISSN: 19383207     Source Type: Journal    
DOI: 10.3945/ajcn.110.005744     Document Type: Review

References (32)

1. O'Dell BL, Reeves PG. Zinc status and food intake. In: Mills CF, ed. Zinc in human biology. London, United Kingdom: Springer-Verlag, 1989:173-81.
2. Cousins RJ. Zinc. In: Bowman BA, Russell RM, eds. Present knowledge in nutrition. Washington, DC: ILSI Press, 2006:445-57.
3. Eide DJ. Zinc transporters and the cellular trafficking of zinc. Biochim Biophys Acta 2006;1763:711-22.
4. Golden MHN. The diagnosis of zinc deficiency. In: Mills CF, ed. Zinc in human biology. London, United Kingdom: Springer-Verlag, 1989:173-81.
5. Baer MT, King JC. Tissue zinc levels and zinc excretion during experimental zinc depletion in young men. Am J Clin Nutr 1984;39:556-70. (Pubitemid 14135368)
6. King JC, Shames DM, Woodhouse LR. Zinc homeostasis in humans. J Nutr 2000;130:1360S-6S. (Pubitemid 30244130)
7. Williams RB, Mills CF. The experimental production of zinc deficiency in the rat. Br J Nutr 1970;24:989-1003.
8. Flanagan PR. A model to produce pure zinc deficiency in rats and its use to demonstrate that dietary phytate increases the excretion of endogenous zinc. J Nutr 1984;114:493-502. (Pubitemid 14166275)
9. King JC, Shames DM, Lowe NM, et al. Effect of acute zinc depletion on zinc homeostasis and plasma zinc kinetics in men. Am J Clin Nutr 2001;74:116-24. (Pubitemid 32574919)
10. Golden MH, Golden BE. Effect of zinc supplementation on the dietary intake, rate of weight gain, and energy cost of tissue deposition in children recovering from severe malnutrition. Am J Clin Nutr 1981;34:900-8. (Pubitemid 11077926)
11. Baer MT, King JC, Tamura T, Margen S. Acne in zinc deficiency. Arch Dermatol 1978;114:1093.
12. Brown KH, Peerson JM, Rivera J, Allen LH. Effect of supplemental zinc on the growth and serum zinc concentrations of prepubertal children: a meta-analysis of randomized controlled trials. Am J Clin Nutr 2002;75:1062-71. (Pubitemid 34547537)
13. Aggett PJ. The assessment of zinc status: a personal view. Proc Nutr Soc 1991;50:9-17.
14. Taylor CM, Goode HF, Aggett PJ, Bremner I, Walker BE, Kelleher J. Symptomatic zinc deficiency in experimental zinc deprivation. J Clin Pathol 1992;45:83-4.
15. Golden BE, Golden MH. Plasma zinc, rate of weight gain, and the energy cost of tissue deposition in children recovering from severe malnutrition on a cow's milk or soya protein based diet. Am J Clin Nutr 1981;34:892-9. (Pubitemid 11077925)
16. King JC. Assessment of zinc status. J Nutr 1990;120(suppl 11):1474-9.
17. Sutherland B. The effect of acute zinc depletion on protein and energy metabolism in men. PhD dissertation. University of California, Berkeley, CA, 1996:260.
18. Coyle P, Philcox JC, Carey LC, Rofe AM. Metallothionein: the multipurpose protein. Cell Mol Life Sci 2002;59:627-47. (Pubitemid 34460681)
19. Bell SG, Vallee BL. The metallothionein/thionein system: an oxidoreductive metabolic zinc link. ChemBioChem 2009;10:55-62.
20. Bremner I, Morrison JN, Wood AM, Arthur JR. Effects of changes in dietary zinc, copper and selenium supply and of endotoxin administration on metallothionein I concentrations in blood cells and urine in the rat. J Nutr 1987;117:1595-602. (Pubitemid 18021175)
21. Sato M, Mehra RK, Bremner I. Measurement of plasma metallothionein-I in the assessment of the zinc status of zinc-deficient and stressed rats. J Nutr 1984;114:1683-9. (Pubitemid 14074842)
22. Lowe NM, Woodhouse LR, Sutherland B, et al. Kinetic parameters and plasma zinc concentration correlate well with net loss and gain of zinc from men. J Nutr 2004;134:2178-81. (Pubitemid 39201582)
23. Gibson RS, Hess SY, Hotz C, Brown KH. Indicators of zinc status at the population level: a review of the evidence. Br J Nutr 2008;99(suppl 3):S14-23. (Pubitemid 351936562)
24. Wessells KR, Jorgensen JM, Hess SY, Woodhouse LR, Peerson JM, Brown KH. Plasma zinc concentration responds rapidly to the initiation and discontinuation of short-term zinc supplementation in healthy men. J Nutr 2010;140(12):2128-33.
25. Wallock LM, King JC, Hambidge KM, English-Westcott JE, Pritts J. Meal-induced changes in plasma, erythrocyte, and urinary zinc concentrations in adult women. Am J Clin Nutr 1993;58:695-701. (Pubitemid 23319958)
26. Brown KH. Effect of infections on plasma zinc concentration and implications for zinc status assessment in low-income countries. Am J Clin Nutr 1998;68:425S-9S. (Pubitemid 28355616)
27. Grider A, Bailey LB, Cousins RJ. Erythrocyte metallothionein as an index of zinc status in humans. Proc Natl Acad Sci USA 1990;87:1259-62.
28. Bremner I, Morrison JN. Assessment of zinc, copper and cadmium status in animals by assay of extracellular metallothionein. Acta Pharmacol Toxicol (Copenh) 1986;59(suppl 7):502-9. (Pubitemid 17180381)
29. Miller LV, Hambidge KM, Naake VL, Hong Z, Westcott JL, Fennessey PV. Size of the zinc pools that exchange rapidly with plasma zinc in humans: alternative techniques for measuring and relation to dietary zinc intake. J Nutr 1994;124:268-76. (Pubitemid 24093966)
30. Jackson MJ, Giugliano R, Giugliano LG, Oliveira EF, Shrimpton R, Swainbank IG. Stable isotope metabolic studies of zinc nutrition in slum-dwelling lactating women in the Amazon valley. Br J Nutr 1988;59:193-203.
31. Feillet-Coudray C, Meunier N, Rambeau M, et al. Long-term moderate zinc supplementation increases exchangeable zinc pool masses in late-middle-aged men: the Zenith Study. Am J Clin Nutr 2005;82:103-10. (Pubitemid 41721866)
32. Pinna K, Woodhouse LR, Sutherland B, Shames DM, King JC. Exchangeable zinc pool masses and turnover are maintained in healthy men with low zinc intakes. J Nutr 2001;131:2288-94. (Pubitemid 32851870)