Strain-specific anti-inflammatory properties of two Akkermansia muciniphila strains on chronic colitis in mice

Frontiers in Cellular and Infection Microbiology

Volumn 9, Issue JUL, 2019, Pages

  Zhai, Rui ^a   Xue, Xinhe ^a   Zhang, Liying ^a   Yang, Xin ^a   Zhao, Liping ^a,b   Zhang, Chenhong ^a  

^a Shanghai Jiao Tong University   (China)

^b the State University of New Jersey   (United States)

Author keywords

Akkermansia muciniphila; Chronic colitis; DSS; Gut microbiota; Strain specificity; Treg

Indexed keywords

GAMMA INTERFERON; INTERLEUKIN 6; INTERLEUKIN 8; NEUTROPHIL GELATINASE ASSOCIATED LIPOCALIN; PROBIOTIC AGENT; RNA 16S; SHORT CHAIN FATTY ACID; TRANSCRIPTION FACTOR FOXP3; TUMOR NECROSIS FACTOR; ANTIINFLAMMATORY AGENT; CYTOKINE; DEXTRAN SULFATE;

AKKERMANSIA MUCINIPHILA; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIINFLAMMATORY ACTIVITY; ARTICLE; CD4+ T LYMPHOCYTE; CELL DIFFERENTIATION; COLITIS; CONTROLLED STUDY; DNA EXTRACTION; DOWN REGULATION; DYSBIOSIS; ENZYME LINKED IMMUNOSORBENT ASSAY; FECES ANALYSIS; FLOW CYTOMETRY; GENE EXPRESSION; GENE SEQUENCE; HISTOLOGY; HT-29 CELL LINE; HUMAN; HUMAN CELL; IMMUNOREGULATION; INFLAMMATION; INFLAMMATORY BOWEL DISEASE; INTESTINE FLORA; MALE; MOUSE; MTT ASSAY; NONHUMAN; NUCLEOTIDE SEQUENCE; POLYMERASE CHAIN REACTION; PROTEIN EXPRESSION; REAL TIME POLYMERASE CHAIN REACTION; REGULATORY T LYMPHOCYTE; RNA EXTRACTION; SCANNING ELECTRON MICROSCOPY; SEQUENCE ANALYSIS; SPLEEN WEIGHT; WHOLE GENOME SEQUENCING; ANIMAL; C57BL MOUSE; CHRONIC DISEASE; CLASSIFICATION; COLON; DISEASE MODEL; FECES; GENETICS; ISOLATION AND PURIFICATION; METABOLISM; MICROBIOLOGY; PATHOLOGY; PHYSIOLOGY; VERRUCOMICROBIA;

ANIMALS; ANTI-INFLAMMATORY AGENTS; CD4-POSITIVE T-LYMPHOCYTES; CHRONIC DISEASE; COLITIS; COLON; CYTOKINES; DEXTRAN SULFATE; DISEASE MODELS, ANIMAL; DYSBIOSIS; FECES; GASTROINTESTINAL MICROBIOME; HT29 CELLS; HUMANS; INTERFERON-GAMMA; INTERLEUKIN-8; MALE; MICE; MICE, INBRED C57BL; PROBIOTICS; RNA, RIBOSOMAL, 16S; TUMOR NECROSIS FACTOR-ALPHA; VERRUCOMICROBIA; WHOLE GENOME SEQUENCING;

EID: 85072726673     PISSN: None     EISSN: 22352988     Source Type: Journal    
DOI: 10.3389/fcimb.2019.00239     Document Type: Article

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