메뉴 건너뛰기




Volumn 61, Issue 11, 2017, Pages

Differential intestinal anti-inflammatory effects of Lactobacillus fermentum and Lactobacillus salivarius in DSS mouse colitis: impact on microRNAs expression and microbiota composition

Author keywords

DSS mouse colitis; Microbiota; MicroRNA; Probiotic; Pyrosequencing

Indexed keywords

BIOLOGICAL MARKER; CYTOKINE; DEXTRAN SULFATE; MICRORNA; NONSTEROID ANTIINFLAMMATORY AGENT; PROBIOTIC AGENT;

EID: 85032665087     PISSN: 16134125     EISSN: 16134133     Source Type: Journal    
DOI: 10.1002/mnfr.201700144     Document Type: Article
Times cited : (149)

References (85)
  • 1
    • 34248136340 scopus 로고    scopus 로고
    • Inflammatory bowel disease: clinical aspects and established and evolving therapies
    • Baumgart, D. C., Sandborn, W. J., Inflammatory bowel disease: clinical aspects and established and evolving therapies. Lancet (London, England) 2007, 369, 1641–1657.
    • (2007) Lancet (London, England) , vol.369 , pp. 1641-1657
    • Baumgart, D.C.1    Sandborn, W.J.2
  • 2
    • 77957867461 scopus 로고    scopus 로고
    • Genes and environment: how will our concepts on the pathophysiology of IBD develop in the future?
    • Kaser, A., Zeissig, S., Blumberg, R. S., Genes and environment: how will our concepts on the pathophysiology of IBD develop in the future? Dig. Dis. 2010, 28, 395–405.
    • (2010) Dig. Dis. , vol.28 , pp. 395-405
    • Kaser, A.1    Zeissig, S.2    Blumberg, R.S.3
  • 3
    • 85007508333 scopus 로고    scopus 로고
    • Roles for intestinal bacteria, viruses, and fungi in pathogenesis of inflammatory bowel diseases and therapeutic approaches
    • Sartor, R. B., Wu, G. D., Roles for intestinal bacteria, viruses, and fungi in pathogenesis of inflammatory bowel diseases and therapeutic approaches. Gastroenterology 2017, 152, 327–339 e324.
    • (2017) Gastroenterology , vol.152 , pp. 327-339 e324
    • Sartor, R.B.1    Wu, G.D.2
  • 4
    • 84961226971 scopus 로고    scopus 로고
    • Crosstalk between microbiota, pathogens and the innate immune responses
    • Gunther, C., Josenhans, C., Wehkamp, J., Crosstalk between microbiota, pathogens and the innate immune responses. Int. J. Med. Microbiol. 2016, 306, 257–265.
    • (2016) Int. J. Med. Microbiol. , vol.306 , pp. 257-265
    • Gunther, C.1    Josenhans, C.2    Wehkamp, J.3
  • 6
    • 84934956407 scopus 로고    scopus 로고
    • MicroRNAs: new players in inflammatory bowel disease
    • Kalla, R., Ventham, N. T., Kennedy, N. A., MicroRNAs: new players in inflammatory bowel disease. Gut 2015, 64, 1008.
    • (2015) Gut , vol.64 , pp. 1008
    • Kalla, R.1    Ventham, N.T.2    Kennedy, N.A.3
  • 7
    • 78049468823 scopus 로고    scopus 로고
    • MicroRNAs control intestinal epithelial differentiation, architecture, and barrier function
    • 1664 e1651
    • McKenna, L. B., Schug, J., Vourekas, A., McKenna, J. B. et al., MicroRNAs control intestinal epithelial differentiation, architecture, and barrier function. Gastroenterology 2010, 139, 1654–1664, 1664 e1651.
    • (2010) Gastroenterology , vol.139 , pp. 1654-1664
    • McKenna, L.B.1    Schug, J.2    Vourekas, A.3    McKenna, J.B.4
  • 8
    • 24344494340 scopus 로고    scopus 로고
    • How microRNAs control cell division, differentiation and death
    • Miska, E. A., How microRNAs control cell division, differentiation and death. Curr. Opin. Genet. Dev. 2005, 15, 563–568.
    • (2005) Curr. Opin. Genet. Dev. , vol.15 , pp. 563-568
    • Miska, E.A.1
  • 9
    • 53549097349 scopus 로고    scopus 로고
    • MicroRNAs: key players in the immune system, differentiation, tumorigenesis and cell death
    • Schickel, R., Boyerinas, B., Park, S. M., Peter, M. E., MicroRNAs: key players in the immune system, differentiation, tumorigenesis and cell death. Oncogene 2008, 27, 5959–5974.
    • (2008) Oncogene , vol.27 , pp. 5959-5974
    • Schickel, R.1    Boyerinas, B.2    Park, S.M.3    Peter, M.E.4
  • 10
    • 79955753386 scopus 로고    scopus 로고
    • Microbiota modulate host gene expression via microRNAs
    • Dalmasso, G., Nguyen, H. T., Yan, Y., Laroui, H. et al., Microbiota modulate host gene expression via microRNAs. PLoS One 2011, 6, e19293.
    • (2011) PLoS One , vol.6
    • Dalmasso, G.1    Nguyen, H.T.2    Yan, Y.3    Laroui, H.4
  • 11
    • 79251644886 scopus 로고    scopus 로고
    • The microbe-derived short chain fatty acid butyrate targets miRNA-dependent p21 gene expression in human colon cancer
    • Hu, S., Dong, T. S., Dalal, S. R., Wu, F. et al., The microbe-derived short chain fatty acid butyrate targets miRNA-dependent p21 gene expression in human colon cancer. PLoS One 2011, 6, e16221.
    • (2011) PLoS One , vol.6
    • Hu, S.1    Dong, T.S.2    Dalal, S.R.3    Wu, F.4
  • 12
    • 84896051012 scopus 로고    scopus 로고
    • Downregulation of microRNA-107 in intestinal CD11c(+) myeloid cells in response to microbiota and proinflammatory cytokines increases IL-23p19 expression
    • Xue, X., Cao, A. T., Cao, X., Yao, S. et al., Downregulation of microRNA-107 in intestinal CD11c(+) myeloid cells in response to microbiota and proinflammatory cytokines increases IL-23p19 expression. Eur. J. Immunol. 2014, 44, 673–682.
    • (2014) Eur. J. Immunol. , vol.44 , pp. 673-682
    • Xue, X.1    Cao, A.T.2    Cao, X.3    Yao, S.4
  • 13
    • 58149085504 scopus 로고    scopus 로고
    • MicroRNA control in the immune system: basic principles
    • Xiao, C., Rajewsky, K., MicroRNA control in the immune system: basic principles. Cell 2009, 136, 26–36.
    • (2009) Cell , vol.136 , pp. 26-36
    • Xiao, C.1    Rajewsky, K.2
  • 14
    • 84918810194 scopus 로고    scopus 로고
    • Implication of miRNAs for inflammatory bowel disease treatment: systematic review
    • Chen, W. X., Ren, L. H., Shi, R. H., Implication of miRNAs for inflammatory bowel disease treatment: systematic review. World J. Gastrointest. Pathophysiol. 2014, 5, 63–70.
    • (2014) World J. Gastrointest. Pathophysiol. , vol.5 , pp. 63-70
    • Chen, W.X.1    Ren, L.H.2    Shi, R.H.3
  • 15
    • 84919493836 scopus 로고    scopus 로고
    • The emerging role of miRNAs in inflammatory bowel disease: a review
    • Chapman, C. G., Pekow, J., The emerging role of miRNAs in inflammatory bowel disease: a review. Therap. Adv. Gastroenterol. 2015, 8, 4–22.
    • (2015) Therap. Adv. Gastroenterol. , vol.8 , pp. 4-22
    • Chapman, C.G.1    Pekow, J.2
  • 16
    • 84959905989 scopus 로고    scopus 로고
    • miRNAs as new molecular insights into inflammatory bowel disease: Crucial regulators in autoimmunity and inflammation
    • Xu, X. M., Zhang, H. J., miRNAs as new molecular insights into inflammatory bowel disease: Crucial regulators in autoimmunity and inflammation. World J. Gastroenterol. 2016, 22, 2206–2218.
    • (2016) World J. Gastroenterol. , vol.22 , pp. 2206-2218
    • Xu, X.M.1    Zhang, H.J.2
  • 17
    • 80053581738 scopus 로고    scopus 로고
    • MicroRNA regulation of intestinal epithelial tight junction permeability
    • Ye, D., Guo, S., Al-Sadi, R., Ma, T. Y., MicroRNA regulation of intestinal epithelial tight junction permeability. Gastroenterology 2011, 141, 1323–1333.
    • (2011) Gastroenterology , vol.141 , pp. 1323-1333
    • Ye, D.1    Guo, S.2    Al-Sadi, R.3    Ma, T.Y.4
  • 18
    • 81255214942 scopus 로고    scopus 로고
    • Role of miR-150-targeting c-Myb in colonic epithelial disruption during dextran sulphate sodium-induced murine experimental colitis and human ulcerative colitis
    • Bian, Z., Li, L., Cui, J., Zhang, H. et al., Role of miR-150-targeting c-Myb in colonic epithelial disruption during dextran sulphate sodium-induced murine experimental colitis and human ulcerative colitis. J. Pathol. 2011, 225, 544–553.
    • (2011) J. Pathol. , vol.225 , pp. 544-553
    • Bian, Z.1    Li, L.2    Cui, J.3    Zhang, H.4
  • 19
    • 84985015802 scopus 로고    scopus 로고
    • MicroRNA-124 promotes intestinal inflammation by targeting Aryl hydrocarbon receptor in Crohn's disease
    • Zhao, Y., Ma, T., Chen, W., Chen, Y. et al., MicroRNA-124 promotes intestinal inflammation by targeting Aryl hydrocarbon receptor in Crohn's disease. J. Crohns Colitis 2016, 10, 703–712.
    • (2016) J. Crohns Colitis , vol.10 , pp. 703-712
    • Zhao, Y.1    Ma, T.2    Chen, W.3    Chen, Y.4
  • 20
    • 84871695308 scopus 로고    scopus 로고
    • Up-regulation of microRNA-126 may contribute to pathogenesis of ulcerative colitis via regulating NF-kappaB inhibitor IkappaBalpha
    • Feng, X., Wang, H., Ye, S., Guan, J. et al., Up-regulation of microRNA-126 may contribute to pathogenesis of ulcerative colitis via regulating NF-kappaB inhibitor IkappaBalpha. PloS one 2012, 7, e52782.
    • (2012) PloS one , vol.7
    • Feng, X.1    Wang, H.2    Ye, S.3    Guan, J.4
  • 21
    • 84908270734 scopus 로고    scopus 로고
    • miR-155 deficiency protects mice from experimental colitis by reducing T helper type 1/type 17 responses
    • Singh, U. P., Murphy, A. E., Enos, R. T., Shamran, H. A. et al., miR-155 deficiency protects mice from experimental colitis by reducing T helper type 1/type 17 responses. Immunology 2014, 143, 478–489.
    • (2014) Immunology , vol.143 , pp. 478-489
    • Singh, U.P.1    Murphy, A.E.2    Enos, R.T.3    Shamran, H.A.4
  • 22
    • 84898809123 scopus 로고    scopus 로고
    • The microbiome in inflammatory bowel disease: current status and the future ahead
    • Kostic, A. D., Xavier, R. J., Gevers, D., The microbiome in inflammatory bowel disease: current status and the future ahead. Gastroenterology 2014, 146, 1489–1499.
    • (2014) Gastroenterology , vol.146 , pp. 1489-1499
    • Kostic, A.D.1    Xavier, R.J.2    Gevers, D.3
  • 23
    • 84917679127 scopus 로고    scopus 로고
    • MicroRNAs and the regulation of intestinal homeostasis
    • Runtsch, M. C., Round, J. L., O'Connell, R. M., MicroRNAs and the regulation of intestinal homeostasis. Front. Genet. 2014, 5, 347.
    • (2014) Front. Genet. , vol.5 , pp. 347
    • Runtsch, M.C.1    Round, J.L.2    O'Connell, R.M.3
  • 24
    • 84937526310 scopus 로고    scopus 로고
    • Spicing up the treatment of mild to moderate ulcerative colitis
    • Bernstein, C. N., Spicing up the treatment of mild to moderate ulcerative colitis. Clin. Gastroenterol. Hepatol. 2015, 13, 1450–1452.
    • (2015) Clin. Gastroenterol. Hepatol. , vol.13 , pp. 1450-1452
    • Bernstein, C.N.1
  • 25
    • 75149161836 scopus 로고    scopus 로고
    • The second European evidence-based consensus on the diagnosis and management of Crohn's disease: Current management
    • Dignass, A., Van Assche, G., Lindsay, J. O., Lemann, M. et al., The second European evidence-based consensus on the diagnosis and management of Crohn's disease: Current management. J Crohns Colitis 2010, 4, 28–62.
    • (2010) J Crohns Colitis , vol.4 , pp. 28-62
    • Dignass, A.1    Van Assche, G.2    Lindsay, J.O.3    Lemann, M.4
  • 26
    • 84959930520 scopus 로고    scopus 로고
    • Diet therapy for inflammatory bowel diseases: the established and the new
    • Durchschein, F., Petritsch, W., Hammer, H. F., Diet therapy for inflammatory bowel diseases: the established and the new. World J. Gastroenterol. 2016, 22, 2179–2194.
    • (2016) World J. Gastroenterol. , vol.22 , pp. 2179-2194
    • Durchschein, F.1    Petritsch, W.2    Hammer, H.F.3
  • 27
    • 84994234442 scopus 로고    scopus 로고
    • The role of dietary supplements in inflammatory bowel disease: a systematic review
    • Rossi, R. E., Whyand, T., Murray, C. D., Hamilton, M. I. et al., The role of dietary supplements in inflammatory bowel disease: a systematic review. Eur J Gastroenterol Hepatol 2016, 28, 1357–1364.
    • (2016) Eur J Gastroenterol Hepatol , vol.28 , pp. 1357-1364
    • Rossi, R.E.1    Whyand, T.2    Murray, C.D.3    Hamilton, M.I.4
  • 28
    • 80053918916 scopus 로고    scopus 로고
    • Lessons from probiotic-host interaction studies in murine models of experimental colitis
    • Claes, I. J., De Keersmaecker, S. C., Vanderleyden, J., Lebeer, S., Lessons from probiotic-host interaction studies in murine models of experimental colitis. Mol. Nutr. Food Res. 2011, 55, 1441–1453.
    • (2011) Mol. Nutr. Food Res. , vol.55 , pp. 1441-1453
    • Claes, I.J.1    De Keersmaecker, S.C.2    Vanderleyden, J.3    Lebeer, S.4
  • 29
    • 85020046878 scopus 로고    scopus 로고
    • Evidence of the anti-inflammatory effects of probiotics and synbiotics in intestinal chronic diseases
    • Plaza-Diaz, J., Ruiz-Ojeda, F. J., Vilchez-Padial, L. M., Gil, A., Evidence of the anti-inflammatory effects of probiotics and synbiotics in intestinal chronic diseases. Nutrients 2017, 9, 555.
    • (2017) Nutrients , vol.9 , pp. 555
    • Plaza-Diaz, J.1    Ruiz-Ojeda, F.J.2    Vilchez-Padial, L.M.3    Gil, A.4
  • 30
    • 84860667500 scopus 로고    scopus 로고
    • The immunomodulatory properties of viable Lactobacillus salivarius ssp. salivarius CECT5713 are not restricted to the large intestine
    • Arribas, B., Garrido-Mesa, N., Peran, L., Camuesco, D. et al., The immunomodulatory properties of viable Lactobacillus salivarius ssp. salivarius CECT5713 are not restricted to the large intestine. Eur J Nutr 2012, 51, 365–374.
    • (2012) Eur J Nutr , vol.51 , pp. 365-374
    • Arribas, B.1    Garrido-Mesa, N.2    Peran, L.3    Camuesco, D.4
  • 31
    • 84927668020 scopus 로고    scopus 로고
    • The viability of Lactobacillus fermentum CECT5716 is not essential to exert intestinal anti-inflammatory properties
    • Rodriguez-Nogales, A., Algieri, F., Vezza, T., Garrido-Mesa, N. et al., The viability of Lactobacillus fermentum CECT5716 is not essential to exert intestinal anti-inflammatory properties. Food Funct 2015, 6, 1176–1184.
    • (2015) Food Funct , vol.6 , pp. 1176-1184
    • Rodriguez-Nogales, A.1    Algieri, F.2    Vezza, T.3    Garrido-Mesa, N.4
  • 32
    • 26244468974 scopus 로고    scopus 로고
    • Preventative effects of a probiotic, Lactobacillus salivarius ssp. salivarius, in the TNBS model of rat colitis
    • Peran, L., Camuesco, D., Comalada, M., Nieto, A. et al., Preventative effects of a probiotic, Lactobacillus salivarius ssp. salivarius, in the TNBS model of rat colitis. World J. Gastroenterol. 2005, 11, 5185–5192.
    • (2005) World J. Gastroenterol. , vol.11 , pp. 5185-5192
    • Peran, L.1    Camuesco, D.2    Comalada, M.3    Nieto, A.4
  • 33
    • 33749537680 scopus 로고    scopus 로고
    • Lactobacillus fermentum, a probiotic capable to release glutathione, prevents colonic inflammation in the TNBS model of rat colitis
    • Peran, L., Camuesco, D., Comalada, M., Nieto, A. et al., Lactobacillus fermentum, a probiotic capable to release glutathione, prevents colonic inflammation in the TNBS model of rat colitis. Int. J. Colorectal Dis. 2006, 21, 737–746.
    • (2006) Int. J. Colorectal Dis. , vol.21 , pp. 737-746
    • Peran, L.1    Camuesco, D.2    Comalada, M.3    Nieto, A.4
  • 34
    • 70349509222 scopus 로고    scopus 로고
    • Lactobacillus fermentum CECT 5716 prevents and reverts intestinal damage on TNBS-induced colitis in mice
    • Mane, J., Loren, V., Pedrosa, E., Ojanguren, I. et al., Lactobacillus fermentum CECT 5716 prevents and reverts intestinal damage on TNBS-induced colitis in mice. Inflamm. Bowel Dis. 2009, 15, 1155–1163.
    • (2009) Inflamm. Bowel Dis. , vol.15 , pp. 1155-1163
    • Mane, J.1    Loren, V.2    Pedrosa, E.3    Ojanguren, I.4
  • 35
    • 85020269139 scopus 로고    scopus 로고
    • A synbiotic composed of Lactobacillus fermentum CECT5716 and FOS prevents the development of fatty acid liver and glycemic alterations in rats fed a high fructose diet associated with changes in the microbiota
    • Rivero-Gutierrez, B., Gamez-Belmonte, R., Suarez, M. D., Lavin, J. L. et al., A synbiotic composed of Lactobacillus fermentum CECT5716 and FOS prevents the development of fatty acid liver and glycemic alterations in rats fed a high fructose diet associated with changes in the microbiota. Mol. Nutr. Food Res. 2017, 61, 1600622.
    • (2017) Mol. Nutr. Food Res. , vol.61 , pp. 1600622
    • Rivero-Gutierrez, B.1    Gamez-Belmonte, R.2    Suarez, M.D.3    Lavin, J.L.4
  • 36
    • 33847109825 scopus 로고    scopus 로고
    • A comparative study of the preventative effects exerted by two probiotics, Lactobacillus reuteri and Lactobacillus fermentum, in the trinitrobenzenesulfonic acid model of rat colitis
    • Peran, L., Sierra, S., Comalada, M., Lara-Villoslada, F. et al., A comparative study of the preventative effects exerted by two probiotics, Lactobacillus reuteri and Lactobacillus fermentum, in the trinitrobenzenesulfonic acid model of rat colitis. Br. J. Nutr. 2007, 97, 96–103.
    • (2007) Br. J. Nutr. , vol.97 , pp. 96-103
    • Peran, L.1    Sierra, S.2    Comalada, M.3    Lara-Villoslada, F.4
  • 37
    • 0031945843 scopus 로고    scopus 로고
    • Differential susceptibility of inbred mouse strains to dextran sulfate sodium-induced colitis
    • Mahler, M., Bristol, I. J., Leiter, E. H., Workman, A. E. et al., Differential susceptibility of inbred mouse strains to dextran sulfate sodium-induced colitis. Am. J. Physiol. 1998, 274, G544–G551.
    • (1998) Am. J. Physiol. , vol.274 , pp. G544-G551
    • Mahler, M.1    Bristol, I.J.2    Leiter, E.H.3    Workman, A.E.4
  • 38
    • 0027224059 scopus 로고
    • Clinicopathologic study of dextran sulfate sodium experimental murine colitis
    • Cooper, H. S., Murthy, S. N., Shah, R. S., Sedergran, D. J., Clinicopathologic study of dextran sulfate sodium experimental murine colitis. Lab. Invest. 1993, 69, 238–249.
    • (1993) Lab. Invest. , vol.69 , pp. 238-249
    • Cooper, H.S.1    Murthy, S.N.2    Shah, R.S.3    Sedergran, D.J.4
  • 39
    • 77953610970 scopus 로고    scopus 로고
    • Muc2 protects against lethal infectious colitis by disassociating pathogenic and commensal bacteria from the colonic mucosa
    • Bergstrom, K. S., Kissoon-Singh, V., Gibson, D. L., Ma, C. et al., Muc2 protects against lethal infectious colitis by disassociating pathogenic and commensal bacteria from the colonic mucosa. PLoS Pathog. 2010, 6, e1000902.
    • (2010) PLoS Pathog. , vol.6
    • Bergstrom, K.S.1    Kissoon-Singh, V.2    Gibson, D.L.3    Ma, C.4
  • 40
    • 84855692561 scopus 로고    scopus 로고
    • The intestinal anti-inflammatory effect of dersalazine sodium is related to a down-regulation in IL-17 production in experimental models of rodent colitis
    • Camuesco, D., Rodriguez-Cabezas, M. E., Garrido-Mesa, N., Cueto-Sola, M. et al., The intestinal anti-inflammatory effect of dersalazine sodium is related to a down-regulation in IL-17 production in experimental models of rodent colitis. Br. J. Pharmacol. 2012, 165, 729–740.
    • (2012) Br. J. Pharmacol. , vol.165 , pp. 729-740
    • Camuesco, D.1    Rodriguez-Cabezas, M.E.2    Garrido-Mesa, N.3    Cueto-Sola, M.4
  • 41
    • 84928782424 scopus 로고    scopus 로고
    • A new therapeutic association to manage relapsing experimental colitis: doxycycline plus Saccharomyces boulardii
    • Garrido-Mesa, J., Algieri, F., Rodriguez-Nogales, A., Utrilla, M. P. et al., A new therapeutic association to manage relapsing experimental colitis: doxycycline plus Saccharomyces boulardii. Pharmacological Res. 2015, 97, 48–63.
    • (2015) Pharmacological Res. , vol.97 , pp. 48-63
    • Garrido-Mesa, J.1    Algieri, F.2    Rodriguez-Nogales, A.3    Utrilla, M.P.4
  • 42
    • 80555149387 scopus 로고    scopus 로고
    • The association of minocycline and the probiotic Escherichia coli Nissle 1917 results in an additive beneficial effect in a DSS model of reactivated colitis in mice
    • Garrido-Mesa, N., Utrilla, P., Comalada, M., Zorrilla, P. et al., The association of minocycline and the probiotic Escherichia coli Nissle 1917 results in an additive beneficial effect in a DSS model of reactivated colitis in mice. Biochem. Pharmacol. 2011, 82, 1891–1900.
    • (2011) Biochem. Pharmacol. , vol.82 , pp. 1891-1900
    • Garrido-Mesa, N.1    Utrilla, P.2    Comalada, M.3    Zorrilla, P.4
  • 43
    • 77952243141 scopus 로고    scopus 로고
    • QIIME allows analysis of high-throughput community sequencing data
    • Caporaso, J. G., Kuczynski, J., Stombaugh, J., Bittinger, K. et al., QIIME allows analysis of high-throughput community sequencing data. Nat. Methods 2010, 7, 335–336.
    • (2010) Nat. Methods , vol.7 , pp. 335-336
    • Caporaso, J.G.1    Kuczynski, J.2    Stombaugh, J.3    Bittinger, K.4
  • 44
    • 84964603286 scopus 로고    scopus 로고
    • Impact of early gut microbiota on immune and metabolic development and function
    • Wang, M., Monaco, M. H., Donovan, S. M., Impact of early gut microbiota on immune and metabolic development and function. Semin Fetal Neonatal Med 2016, 21, 380–387.
    • (2016) Semin Fetal Neonatal Med , vol.21 , pp. 380-387
    • Wang, M.1    Monaco, M.H.2    Donovan, S.M.3
  • 45
    • 84959882996 scopus 로고    scopus 로고
    • Bile acid modifications at the microbe-host interface: potential for nutraceutical and pharmaceutical interventions in host health
    • Joyce, S. A., Gahan, C. G., Bile acid modifications at the microbe-host interface: potential for nutraceutical and pharmaceutical interventions in host health. Annu Rev Food Sci Technol 2016, 7, 313–333.
    • (2016) Annu Rev Food Sci Technol , vol.7 , pp. 313-333
    • Joyce, S.A.1    Gahan, C.G.2
  • 46
    • 85015348385 scopus 로고    scopus 로고
    • Effects of probiotics on gut microbiota in patients with inflammatory bowel disease: a double-blind, placebo-controlled clinical trial
    • Shadnoush, M., Hosseini, R. S., Khalilnezhad, A., Navai, L. et al., Effects of probiotics on gut microbiota in patients with inflammatory bowel disease: a double-blind, placebo-controlled clinical trial. Korean J. Gastroenterol. 2015, 65, 215–221.
    • (2015) Korean J. Gastroenterol. , vol.65 , pp. 215-221
    • Shadnoush, M.1    Hosseini, R.S.2    Khalilnezhad, A.3    Navai, L.4
  • 48
    • 33644774565 scopus 로고    scopus 로고
    • Evolving knowledge and therapy of inflammatory bowel disease
    • Korzenik, J. R., Podolsky, D. K., Evolving knowledge and therapy of inflammatory bowel disease. Nat Rev Drug Discov 2006, 5, 197–209.
    • (2006) Nat Rev Drug Discov , vol.5 , pp. 197-209
    • Korzenik, J.R.1    Podolsky, D.K.2
  • 49
    • 10844222740 scopus 로고    scopus 로고
    • The intestinal anti-inflammatory effect of quercitrin is associated with an inhibition in iNOS expression
    • Camuesco, D., Comalada, M., Rodriguez-Cabezas, M. E., Nieto, A. et al., The intestinal anti-inflammatory effect of quercitrin is associated with an inhibition in iNOS expression. Br. J. Pharmacol. 2004, 143, 908–918.
    • (2004) Br. J. Pharmacol. , vol.143 , pp. 908-918
    • Camuesco, D.1    Comalada, M.2    Rodriguez-Cabezas, M.E.3    Nieto, A.4
  • 50
    • 28844444682 scopus 로고    scopus 로고
    • Expression of matrix metalloproteinases-2 and -9 in intestinal tissue of patients with inflammatory bowel diseases
    • Gao, Q., Meijer, M. J., Kubben, F. J., Sier, C. F. et al., Expression of matrix metalloproteinases-2 and -9 in intestinal tissue of patients with inflammatory bowel diseases. Dig Liver Dis 2005, 37, 584–592.
    • (2005) Dig Liver Dis , vol.37 , pp. 584-592
    • Gao, Q.1    Meijer, M.J.2    Kubben, F.J.3    Sier, C.F.4
  • 51
    • 84895493052 scopus 로고    scopus 로고
    • Collagen degradation and neutrophilic infiltration: a vicious circle in inflammatory bowel disease
    • Koelink, P. J., Overbeek, S. A., Braber, S., Morgan, M. E. et al., Collagen degradation and neutrophilic infiltration: a vicious circle in inflammatory bowel disease. Gut 2014, 63, 578–587.
    • (2014) Gut , vol.63 , pp. 578-587
    • Koelink, P.J.1    Overbeek, S.A.2    Braber, S.3    Morgan, M.E.4
  • 52
    • 58649090901 scopus 로고    scopus 로고
    • Targeted epithelial tight junction dysfunction causes immune activation and contributes to development of experimental colitis
    • Su, L., Shen, L., Clayburgh, D. R., Nalle, S. C. et al., Targeted epithelial tight junction dysfunction causes immune activation and contributes to development of experimental colitis. Gastroenterology 2009, 136, 551–563.
    • (2009) Gastroenterology , vol.136 , pp. 551-563
    • Su, L.1    Shen, L.2    Clayburgh, D.R.3    Nalle, S.C.4
  • 53
    • 60549086579 scopus 로고    scopus 로고
    • Differences in goblet cell differentiation between Crohn's disease and ulcerative colitis
    • Gersemann, M., Becker, S., Kubler, I., Koslowski, M. et al., Differences in goblet cell differentiation between Crohn's disease and ulcerative colitis. Differentiation 2009, 77, 84–94.
    • (2009) Differentiation , vol.77 , pp. 84-94
    • Gersemann, M.1    Becker, S.2    Kubler, I.3    Koslowski, M.4
  • 54
    • 61949313980 scopus 로고    scopus 로고
    • Intestinal barrier dysfunction in inflammatory bowel diseases
    • McGuckin, M. A., Eri, R., Simms, L. A., Florin, T. H. et al., Intestinal barrier dysfunction in inflammatory bowel diseases. Inflamm. Bowel Dis. 2009, 15, 100–113.
    • (2009) Inflamm. Bowel Dis. , vol.15 , pp. 100-113
    • McGuckin, M.A.1    Eri, R.2    Simms, L.A.3    Florin, T.H.4
  • 55
    • 77958170401 scopus 로고    scopus 로고
    • Intestinal goblet cells and mucins in health and disease: recent insights and progress
    • Kim, Y. S., Ho, S. B., Intestinal goblet cells and mucins in health and disease: recent insights and progress. Curr Gastroenterol Rep 2010, 12, 319–330.
    • (2010) Curr Gastroenterol Rep , vol.12 , pp. 319-330
    • Kim, Y.S.1    Ho, S.B.2
  • 56
    • 85008414300 scopus 로고    scopus 로고
    • Probiotic mixture VSL#3 reduces colonic inflammation and improves intestinal barrier function in Muc2 mucin-deficient mice
    • Kumar, M., Kissoon-Singh, V., Coria, A. L., Moreau, F. et al., Probiotic mixture VSL#3 reduces colonic inflammation and improves intestinal barrier function in Muc2 mucin-deficient mice. Am. J. Physiol. Gastrointest. Liver Physiol. 2017, 312, G34–G45.
    • (2017) Am. J. Physiol. Gastrointest. Liver Physiol. , vol.312 , pp. G34-G45
    • Kumar, M.1    Kissoon-Singh, V.2    Coria, A.L.3    Moreau, F.4
  • 57
    • 84994633944 scopus 로고    scopus 로고
    • VSL#3 probiotic stimulates T-cell protein tyrosine phosphatase-mediated recovery of IFN-gamma-induced intestinal epithelial barrier defects
    • Krishnan, M., Penrose, H. M., Shah, N. N., Marchelletta, R. R. et al., VSL#3 probiotic stimulates T-cell protein tyrosine phosphatase-mediated recovery of IFN-gamma-induced intestinal epithelial barrier defects. Inflamm. Bowel Dis. 2016, 22, 2811–2823.
    • (2016) Inflamm. Bowel Dis. , vol.22 , pp. 2811-2823
    • Krishnan, M.1    Penrose, H.M.2    Shah, N.N.3    Marchelletta, R.R.4
  • 59
    • 33748928159 scopus 로고    scopus 로고
    • The diverse functions of microRNAs in animal development and disease
    • Kloosterman, W. P., Plasterk, R. H., The diverse functions of microRNAs in animal development and disease. Dev. Cell 2006, 11, 441–450.
    • (2006) Dev. Cell , vol.11 , pp. 441-450
    • Kloosterman, W.P.1    Plasterk, R.H.2
  • 60
    • 77952959170 scopus 로고    scopus 로고
    • Pharmacological potential of RNAi–focus on miRNA
    • Pfeifer, A., Lehmann, H., Pharmacological potential of RNAi–focus on miRNA. Pharmacol. Ther. 2010, 126, 217–227.
    • (2010) Pharmacol. Ther. , vol.126 , pp. 217-227
    • Pfeifer, A.1    Lehmann, H.2
  • 61
    • 82255186392 scopus 로고    scopus 로고
    • Micro-RNAs as regulators and possible diagnostic bio-markers in inflammatory bowel disease
    • Archanioti, P., Gazouli, M., Theodoropoulos, G., Vaiopoulou, A. et al., Micro-RNAs as regulators and possible diagnostic bio-markers in inflammatory bowel disease. J Crohns Colitis 2011, 5, 520–524.
    • (2011) J Crohns Colitis , vol.5 , pp. 520-524
    • Archanioti, P.1    Gazouli, M.2    Theodoropoulos, G.3    Vaiopoulou, A.4
  • 62
    • 77958495102 scopus 로고    scopus 로고
    • MicroRNA-155 promotes autoimmune inflammation by enhancing inflammatory T cell development
    • O'Connell, R. M., Kahn, D., Gibson, W. S., Round, J. L. et al., MicroRNA-155 promotes autoimmune inflammation by enhancing inflammatory T cell development. Immunity 2010, 33, 607–619.
    • (2010) Immunity , vol.33 , pp. 607-619
    • O'Connell, R.M.1    Kahn, D.2    Gibson, W.S.3    Round, J.L.4
  • 63
    • 75649139134 scopus 로고    scopus 로고
    • Physiological and pathological roles for microRNAs in the immune system
    • O'Connell, R. M., Rao, D. S., Chaudhuri, A. A., Baltimore, D., Physiological and pathological roles for microRNAs in the immune system. Nat. Rev. Immunol. 2010, 10, 111–122.
    • (2010) Nat. Rev. Immunol. , vol.10 , pp. 111-122
    • O'Connell, R.M.1    Rao, D.S.2    Chaudhuri, A.A.3    Baltimore, D.4
  • 64
    • 4644309196 scopus 로고    scopus 로고
    • The functions of animal microRNAs
    • Ambros, V., The functions of animal microRNAs. Nature 2004, 431, 350–355.
    • (2004) Nature , vol.431 , pp. 350-355
    • Ambros, V.1
  • 65
    • 68649091506 scopus 로고    scopus 로고
    • The kinase Akt1 controls macrophage response to lipopolysaccharide by regulating microRNAs
    • Androulidaki, A., Iliopoulos, D., Arranz, A., Doxaki, C. et al., The kinase Akt1 controls macrophage response to lipopolysaccharide by regulating microRNAs. Immunity 2009, 31, 220–231.
    • (2009) Immunity , vol.31 , pp. 220-231
    • Androulidaki, A.1    Iliopoulos, D.2    Arranz, A.3    Doxaki, C.4
  • 66
    • 74249094523 scopus 로고    scopus 로고
    • Micro-RNA-155 inhibits IFN-gamma signaling in CD4+ T cells
    • Banerjee, A., Schambach, F., DeJong, C. S., Hammond, S. M. et al., Micro-RNA-155 inhibits IFN-gamma signaling in CD4+ T cells. Eur. J. Immunol. 2010, 40, 225–231.
    • (2010) Eur. J. Immunol. , vol.40 , pp. 225-231
    • Banerjee, A.1    Schambach, F.2    DeJong, C.S.3    Hammond, S.M.4
  • 67
    • 78049340862 scopus 로고    scopus 로고
    • Identification of restricted subsets of mature microRNA abnormally expressed in inactive colonic mucosa of patients with inflammatory bowel disease
    • Fasseu, M., Treton, X., Guichard, C., Pedruzzi, E. et al., Identification of restricted subsets of mature microRNA abnormally expressed in inactive colonic mucosa of patients with inflammatory bowel disease. PloS one 2010, 5, e13160.
    • (2010) PloS one , vol.5
    • Fasseu, M.1    Treton, X.2    Guichard, C.3    Pedruzzi, E.4
  • 68
    • 84867320879 scopus 로고    scopus 로고
    • Cutting edge: miR-223 and EBV miR-BART15 regulate the NLRP3 inflammasome and IL-1beta production
    • Haneklaus, M., Gerlic, M., Kurowska-Stolarska, M., Rainey, A. A. et al., Cutting edge: miR-223 and EBV miR-BART15 regulate the NLRP3 inflammasome and IL-1beta production. J. Immunol. 2012, 189, 3795–3799.
    • (2012) J. Immunol. , vol.189 , pp. 3795-3799
    • Haneklaus, M.1    Gerlic, M.2    Kurowska-Stolarska, M.3    Rainey, A.A.4
  • 69
    • 73849121794 scopus 로고    scopus 로고
    • Identification of miR-145 and miR-146a as mediators of the 5q- syndrome phenotype
    • Starczynowski, D. T., Kuchenbauer, F., Argiropoulos, B., Sung, S. et al., Identification of miR-145 and miR-146a as mediators of the 5q- syndrome phenotype. Nat. Med. 2010, 16, 49–58.
    • (2010) Nat. Med. , vol.16 , pp. 49-58
    • Starczynowski, D.T.1    Kuchenbauer, F.2    Argiropoulos, B.3    Sung, S.4
  • 70
    • 83555161563 scopus 로고    scopus 로고
    • miR-143 and miR-145 are downregulated in ulcerative colitis: putative regulators of inflammation and protooncogenes
    • Pekow, J. R., Dougherty, U., Mustafi, R., Zhu, H. et al., miR-143 and miR-145 are downregulated in ulcerative colitis: putative regulators of inflammation and protooncogenes. Inflamm. Bowel Dis. 2012, 18, 94–100.
    • (2012) Inflamm. Bowel Dis. , vol.18 , pp. 94-100
    • Pekow, J.R.1    Dougherty, U.2    Mustafi, R.3    Zhu, H.4
  • 71
    • 84901318452 scopus 로고    scopus 로고
    • An essential mesenchymal function for miR-143/145 in intestinal epithelial regeneration
    • Chivukula, R. R., Shi, G., Acharya, A., Mills, E. W. et al., An essential mesenchymal function for miR-143/145 in intestinal epithelial regeneration. Cell 2014, 157, 1104–1116.
    • (2014) Cell , vol.157 , pp. 1104-1116
    • Chivukula, R.R.1    Shi, G.2    Acharya, A.3    Mills, E.W.4
  • 72
    • 84865128457 scopus 로고    scopus 로고
    • Circulating microRNAs: novel biomarkers for cardiovascular diseases
    • Xu, J., Zhao, J., Evan, G., Xiao, C. et al., Circulating microRNAs: novel biomarkers for cardiovascular diseases. J. Mol. M. 2012, 90, 865–875.
    • (2012) J. Mol. M. , vol.90 , pp. 865-875
    • Xu, J.1    Zhao, J.2    Evan, G.3    Xiao, C.4
  • 73
    • 77955708471 scopus 로고    scopus 로고
    • MiR-375 frequently downregulated in gastric cancer inhibits cell proliferation by targeting JAK2
    • Ding, L., Xu, Y., Zhang, W., Deng, Y. et al., MiR-375 frequently downregulated in gastric cancer inhibits cell proliferation by targeting JAK2. Cell Res. 2010, 20, 784–793.
    • (2010) Cell Res. , vol.20 , pp. 784-793
    • Ding, L.1    Xu, Y.2    Zhang, W.3    Deng, Y.4
  • 74
    • 84873154173 scopus 로고    scopus 로고
    • Identification of miRNA-miRNA synergistic relationships in colorectal cancer
    • Zhao, X., Song, H., Zuo, Z., Zhu, Y. et al., Identification of miRNA-miRNA synergistic relationships in colorectal cancer. Int. J. Biol. Macromol. 2013, 55, 98–103.
    • (2013) Int. J. Biol. Macromol. , vol.55 , pp. 98-103
    • Zhao, X.1    Song, H.2    Zuo, Z.3    Zhu, Y.4
  • 75
    • 82755189251 scopus 로고    scopus 로고
    • Selective upregulation of microRNA expression in peripheral blood leukocytes in IL-10-/- mice precedes expression in the colon
    • Schaefer, J. S., Montufar-Solis, D., Vigneswaran, N., Klein, J. R., Selective upregulation of microRNA expression in peripheral blood leukocytes in IL-10-/- mice precedes expression in the colon. J. Immunol. 2011, 187, 5834–5841.
    • (2011) J. Immunol. , vol.187 , pp. 5834-5841
    • Schaefer, J.S.1    Montufar-Solis, D.2    Vigneswaran, N.3    Klein, J.R.4
  • 76
    • 84866916840 scopus 로고    scopus 로고
    • Regulation of TLR4, p38 MAPkinase, IkappaB and miRNAs by inactivated strains of lactobacilli in human dendritic cells
    • Giahi, L., Aumueller, E., Elmadfa, I., Haslberger, A. G., Regulation of TLR4, p38 MAPkinase, IkappaB and miRNAs by inactivated strains of lactobacilli in human dendritic cells. Benef Microbes 2012, 3, 91–98.
    • (2012) Benef Microbes , vol.3 , pp. 91-98
    • Giahi, L.1    Aumueller, E.2    Elmadfa, I.3    Haslberger, A.G.4
  • 77
    • 80052473669 scopus 로고    scopus 로고
    • The intestinal microbiota and chronic disorders of the gut
    • DuPont, A. W., DuPont, H. L., The intestinal microbiota and chronic disorders of the gut. Nat Rev Gastroenterol Hepatol 2011, 8, 523–531.
    • (2011) Nat Rev Gastroenterol Hepatol , vol.8 , pp. 523-531
    • DuPont, A.W.1    DuPont, H.L.2
  • 78
    • 79952108387 scopus 로고    scopus 로고
    • Probiotics and the gut microbiota in intestinal health and disease
    • Gareau, M. G., Sherman, P. M., Walker, W. A., Probiotics and the gut microbiota in intestinal health and disease. Nat Rev Gastroenterol Hepatol 2010, 7, 503–514.
    • (2010) Nat Rev Gastroenterol Hepatol , vol.7 , pp. 503-514
    • Gareau, M.G.1    Sherman, P.M.2    Walker, W.A.3
  • 79
    • 35348857386 scopus 로고    scopus 로고
    • Molecular-phylogenetic characterization of microbial community imbalances in human inflammatory bowel diseases
    • Frank, D. N., St Amand, A. L., Feldman, R. A., Boedeker, E. C. et al., Molecular-phylogenetic characterization of microbial community imbalances in human inflammatory bowel diseases. Proc. Natl. Acad. Sci. U.S.A. 2007, 104, 13780–13785.
    • (2007) Proc. Natl. Acad. Sci. U.S.A. , vol.104 , pp. 13780-13785
    • Frank, D.N.1    St Amand, A.L.2    Feldman, R.A.3    Boedeker, E.C.4
  • 80
    • 78650973052 scopus 로고    scopus 로고
    • High-throughput clone library analysis of the mucosa-associated microbiota reveals dysbiosis and differences between inflamed and non-inflamed regions of the intestine in inflammatory bowel disease
    • Walker, A. W., Sanderson, J. D., Churcher, C., Parkes, G. C. et al., High-throughput clone library analysis of the mucosa-associated microbiota reveals dysbiosis and differences between inflamed and non-inflamed regions of the intestine in inflammatory bowel disease. BMC Microbiol. 2011, 11, 7.
    • (2011) BMC Microbiol. , vol.11 , pp. 7
    • Walker, A.W.1    Sanderson, J.D.2    Churcher, C.3    Parkes, G.C.4
  • 81
    • 84927689278 scopus 로고    scopus 로고
    • A potential role for regulatory T-cells in the amelioration of DSS induced colitis by dietary non-digestible polysaccharides
    • Hartog, A., Belle, F. N., Bastiaans, J., de Graaff, P. et al., A potential role for regulatory T-cells in the amelioration of DSS induced colitis by dietary non-digestible polysaccharides. J. Nutr. Biochem. 2015, 26, 227–233.
    • (2015) J. Nutr. Biochem. , vol.26 , pp. 227-233
    • Hartog, A.1    Belle, F.N.2    Bastiaans, J.3    de Graaff, P.4
  • 82
    • 84904048875 scopus 로고    scopus 로고
    • A decrease of the butyrate-producing species Roseburia hominis and Faecalibacterium prausnitzii defines dysbiosis in patients with ulcerative colitis
    • Machiels, K., Joossens, M., Sabino, J., De Preter, V. et al., A decrease of the butyrate-producing species Roseburia hominis and Faecalibacterium prausnitzii defines dysbiosis in patients with ulcerative colitis. Gut 2014, 63, 1275–1283.
    • (2014) Gut , vol.63 , pp. 1275-1283
    • Machiels, K.1    Joossens, M.2    Sabino, J.3    De Preter, V.4
  • 83
    • 84886782819 scopus 로고    scopus 로고
    • Therapeutic potential of fecal microbiota transplantation
    • Smits, L. P., Bouter, K. E., de Vos, W. M., Borody, T. J. et al., Therapeutic potential of fecal microbiota transplantation. Gastroenterology 2013, 145, 946–953.
    • (2013) Gastroenterology , vol.145 , pp. 946-953
    • Smits, L.P.1    Bouter, K.E.2    de Vos, W.M.3    Borody, T.J.4
  • 84
    • 77956475525 scopus 로고    scopus 로고
    • IL-2 is positively involved in the development of colitogenic CD4+ IL-7R alpha high memory T cells in chronic colitis
    • Kameyama, K., Nemoto, Y., Kanai, T., Shinohara, T. et al., IL-2 is positively involved in the development of colitogenic CD4+ IL-7R alpha high memory T cells in chronic colitis. Eur. J. Immunol. 2010, 40, 2423–2436.
    • (2010) Eur. J. Immunol. , vol.40 , pp. 2423-2436
    • Kameyama, K.1    Nemoto, Y.2    Kanai, T.3    Shinohara, T.4
  • 85
    • 80555127486 scopus 로고    scopus 로고
    • Redox biology of the intestine
    • Circu, M. L., Aw, T. Y., Redox biology of the intestine. Free Radic. Res. 2011, 45, 1245–1266.
    • (2011) Free Radic. Res. , vol.45 , pp. 1245-1266
    • Circu, M.L.1    Aw, T.Y.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.