-
1
-
-
85030675839
-
Causes, characteristics, and consequences of metabolically unhealthy normal weight in humans
-
28768170
-
Stefan N, Schick F, Haring HU. Causes, characteristics, and consequences of metabolically unhealthy normal weight in humans. Cell Metabol. (2017) 26:292–300. 10.1016/j.cmet.2017.07.00828768170
-
(2017)
Cell Metabol
, vol.26
, pp. 292-300
-
-
Stefan, N.1
Schick, F.2
Haring, H.U.3
-
2
-
-
85031117659
-
Metabolically healthy obese and incident cardiovascular disease events among 3
-
28911506,.5 million men and women
-
Caleyachetty R, Thomas GN, Toulis KA, Mohammed N, Gokhale KM, Balachandran K. Metabolically healthy obese and incident cardiovascular disease events among 3.5 million men and women. J Am Coll Cardiol. (2017) 70:1429–37. 10.1016/j.jacc.2017.07.76328911506
-
(2017)
J Am Coll Cardiol
, vol.70
, pp. 1429-1437
-
-
Caleyachetty, R.1
Thomas, G.N.2
Toulis, K.A.3
Mohammed, N.4
Gokhale, K.M.5
Balachandran, K.6
-
3
-
-
48249125862
-
Changes in gut microbiota control metabolic endotoxemia-induced inflammation in high-fat diet-induced obesity and diabetes in mice
-
18305141
-
Cani PD, Bibiloni R, Knauf C, Waget A, Neyrinck AM, Delzenne NM. Changes in gut microbiota control metabolic endotoxemia-induced inflammation in high-fat diet-induced obesity and diabetes in mice. Diabetes. (2008) 57:1470–81. 10.2337/db07-140318305141
-
(2008)
Diabetes
, vol.57
, pp. 1470-1481
-
-
Cani, P.D.1
Bibiloni, R.2
Knauf, C.3
Waget, A.4
Neyrinck, A.M.5
Delzenne, N.M.6
-
4
-
-
85043240875
-
Hyperglycemia drives intestinal barrier dysfunction and risk for enteric infection
-
29519916
-
Thaiss CA, Levy M, Grosheva I, Zheng D, Soffer E, Blacher E. Hyperglycemia drives intestinal barrier dysfunction and risk for enteric infection. Science. (2018) 359:1376–83. 10.1126/science.aar331829519916
-
(2018)
Science
, vol.359
, pp. 1376-1383
-
-
Thaiss, C.A.1
Levy, M.2
Grosheva, I.3
Zheng, D.4
Soffer, E.5
Blacher, E.6
-
5
-
-
84857682579
-
Determinants of colonic barrier function in inflammatory bowel disease and potential therapeutics
-
22219336
-
Hering NA, Fromm M, Schulzke JD. Determinants of colonic barrier function in inflammatory bowel disease and potential therapeutics. J Physiol. (2012) 590:1035–44. 10.1113/jphysiol.2011.22456822219336
-
(2012)
J Physiol
, vol.590
, pp. 1035-1044
-
-
Hering, N.A.1
Fromm, M.2
Schulzke, J.D.3
-
6
-
-
85016760436
-
Gut microbiota in cardiovascular health and disease
-
28360349
-
Tang WH, Kitai T, Hazen SL. Gut microbiota in cardiovascular health and disease. Circ Res. (2017) 120:1183–96. 10.1161/CIRCRESAHA.117.30971528360349
-
(2017)
Circ Res
, vol.120
, pp. 1183-1196
-
-
Tang, W.H.1
Kitai, T.2
Hazen, S.L.3
-
7
-
-
84990234576
-
Signals from the gut microbiota to distant organs in physiology and disease
-
27711063
-
Schroeder BO, Backhed F. Signals from the gut microbiota to distant organs in physiology and disease. Nat Med. (2016) 22:1079–89. 10.1038/nm.418527711063
-
(2016)
Nat Med
, vol.22
, pp. 1079-1089
-
-
Schroeder, B.O.1
Backhed, F.2
-
8
-
-
85041844679
-
Microbial modulation of cardiovascular disease
-
29307889
-
Brown JM, Hazen SL. Microbial modulation of cardiovascular disease. Nat Rev Microbiol. (2018) 16:171–81. 10.1038/nrmicro.2017.14929307889
-
(2018)
Nat Rev Microbiol
, vol.16
, pp. 171-181
-
-
Brown, J.M.1
Hazen, S.L.2
-
9
-
-
84864270714
-
ACE2 links amino acid malnutrition to microbial ecology and intestinal inflammation
-
22837003
-
Hashimoto T, Perlot T, Rehman A, Trichereau J, Ishiguro H, Paolino M. ACE2 links amino acid malnutrition to microbial ecology and intestinal inflammation. Nature. (2012) 487:477–81. 10.1038/nature1122822837003
-
(2012)
Nature
, vol.487
, pp. 477-481
-
-
Hashimoto, T.1
Perlot, T.2
Rehman, A.3
Trichereau, J.4
Ishiguro, H.5
Paolino, M.6
-
10
-
-
84882664672
-
Tryptophan catabolites from microbiota engage aryl hydrocarbon receptor and balance mucosal reactivity via interleukin-22
-
23973224
-
Zelante T, Iannitti RG, Cunha C, De Luca A, Giovannini G, Pieraccini G. Tryptophan catabolites from microbiota engage aryl hydrocarbon receptor and balance mucosal reactivity via interleukin-22. Immunity. (2013) 39:372–85. 10.1016/j.immuni.2013.08.00323973224
-
(2013)
Immunity
, vol.39
, pp. 372-385
-
-
Zelante, T.1
Iannitti, R.G.2
Cunha, C.3
De Luca, A.4
Giovannini, G.5
Pieraccini, G.6
-
11
-
-
85041822351
-
Impact of the gut microbiota on intestinal immunity mediated by tryptophan metabolism
-
29468141
-
Gao J, Xu K, Liu H, Liu G, Bai M, Peng C. Impact of the gut microbiota on intestinal immunity mediated by tryptophan metabolism. Front Cell Infect Microbiol. (2018) 8:13. 10.3389/fcimb.2018.0001329468141
-
(2018)
Front Cell Infect Microbiol
, vol.8
, pp. 13
-
-
Gao, J.1
Xu, K.2
Liu, H.3
Liu, G.4
Bai, M.5
Peng, C.6
-
12
-
-
0030035226
-
Cooperative role of interferon regulatory factor 1 and p91 (STAT1) response elements in interferon-gamma-inducible expression of human indoleamine 2,3-dioxygenase gene
-
8663541
-
Chon SY, Hassanain HH, Gupta SL. Cooperative role of interferon regulatory factor 1 and p91 (STAT1) response elements in interferon-gamma-inducible expression of human indoleamine 2,3-dioxygenase gene. J Biol Chem. (1996) 271:17247–52. 10.1074/jbc.271.29.172478663541
-
(1996)
J Biol Chem
, vol.271
, pp. 17247-17252
-
-
Chon, S.Y.1
Hassanain, H.H.2
Gupta, S.L.3
-
13
-
-
5044220930
-
IDO expression by dendritic cells: tolerance and tryptophan catabolism
-
15459668
-
Mellor AL, Munn DH. IDO expression by dendritic cells: tolerance and tryptophan catabolism. Nat Rev Immunol. (2004) 4:762–74. 10.1038/nri145715459668
-
(2004)
Nat Rev Immunol
, vol.4
, pp. 762-774
-
-
Mellor, A.L.1
Munn, D.H.2
-
14
-
-
84959292227
-
IDO in the tumor microenvironment: inflammation, counter-regulation, and tolerance
-
26839260
-
Munn DH, Mellor AL. IDO in the tumor microenvironment: inflammation, counter-regulation, and tolerance. Trends Immunol. (2016) 37:193–207. 10.1016/j.it.2016.01.00226839260
-
(2016)
Trends Immunol
, vol.37
, pp. 193-207
-
-
Munn, D.H.1
Mellor, A.L.2
-
15
-
-
77949261548
-
Kynurenine is an endothelium-derived relaxing factor produced during inflammation
-
20190767
-
Wang Y, Liu H, McKenzie G, Witting PK, Stasch JP, Hahn M. Kynurenine is an endothelium-derived relaxing factor produced during inflammation. Nat Med. (2010) 16:279–85. 10.1038/nm.209220190767
-
(2010)
Nat Med
, vol.16
, pp. 279-285
-
-
Wang, Y.1
Liu, H.2
McKenzie, G.3
Witting, P.K.4
Stasch, J.P.5
Hahn, M.6
-
16
-
-
85042781220
-
Indoleamine 2,3-dioxygenase knockout limits angiotensin II-induced aneurysm in low density lipoprotein receptor-deficient mice fed with high fat diet
-
29494675
-
Metghalchi S, Vandestienne M, Haddad Y, Esposito B, Dairou J, Tedgui A. Indoleamine 2,3-dioxygenase knockout limits angiotensin II-induced aneurysm in low density lipoprotein receptor-deficient mice fed with high fat diet. PLoS ONE. (2018) 13:e0193737. 10.1371/journal.pone.019373729494675
-
(2018)
PLoS ONE
, vol.13
, pp. e0193737
-
-
Metghalchi, S.1
Vandestienne, M.2
Haddad, Y.3
Esposito, B.4
Dairou, J.5
Tedgui, A.6
-
17
-
-
85037085504
-
Tryptophan-derived 3-hydroxyanthranilic acid contributes to angiotensin ii-induced abdominal aortic aneurysm formation in mice in vivo
-
28978552
-
Wang Q, Ding Y, Song P, Zhu H, Okon I, Ding YN. Tryptophan-derived 3-hydroxyanthranilic acid contributes to angiotensin ii-induced abdominal aortic aneurysm formation in mice in vivo. Circulation. (2017) 136:2271–83. 10.1161/CIRCULATIONAHA.117.03097228978552
-
(2017)
Circulation
, vol.136
, pp. 2271-2283
-
-
Wang, Q.1
Ding, Y.2
Song, P.3
Zhu, H.4
Okon, I.5
Ding, Y.N.6
-
18
-
-
67649432744
-
Inhibitors of indoleamine-2,3-dioxygenase for cancer therapy: can we see the wood for the trees?
-
19461669
-
Lob S, Konigsrainer A, Rammensee HG, Opelz G, Terness P. Inhibitors of indoleamine-2,3-dioxygenase for cancer therapy: can we see the wood for the trees? Nat Rev Cancer. (2009) 9:445–52. 10.1038/nrc263919461669
-
(2009)
Nat Rev Cancer
, vol.9
, pp. 445-452
-
-
Lob, S.1
Konigsrainer, A.2
Rammensee, H.G.3
Opelz, G.4
Terness, P.5
-
19
-
-
67749111891
-
Kynurenic acid triggers firm arrest of leukocytes to vascular endothelium under flow conditions
-
19473985
-
Barth MC, Ahluwalia N, Anderson TJ, Hardy GJ, Sinha S, Alvarez-Cardona JA. Kynurenic acid triggers firm arrest of leukocytes to vascular endothelium under flow conditions. J Biol Chem. (2009) 284:19189–95. 10.1074/jbc.M109.02404219473985
-
(2009)
J Biol Chem
, vol.284
, pp. 19189-19195
-
-
Barth, M.C.1
Ahluwalia, N.2
Anderson, T.J.3
Hardy, G.J.4
Sinha, S.5
Alvarez-Cardona, J.A.6
-
20
-
-
85047110060
-
Dietary and microbial oxazoles induce intestinal inflammation by modulating aryl hydrocarbon receptor responses
-
29775592
-
Iyer SS, Gensollen T, Gandhi A, Oh SF, Neves JF, Collin F. Dietary and microbial oxazoles induce intestinal inflammation by modulating aryl hydrocarbon receptor responses. Cell. (2018) 173:1123–34 e11. 10.1016/j.cell.2018.04.03729775592
-
(2018)
Cell
, vol.173
, pp. 1123-1120
-
-
Iyer, S.S.1
Gensollen, T.2
Gandhi, A.3
Oh, S.F.4
Neves, J.F.5
Collin, F.6
-
21
-
-
45949104818
-
IL-17 and therapeutic kynurenines in pathogenic inflammation to fungi
-
18390695
-
Romani L, Zelante T, De Luca A, Fallarino F, Puccetti P. IL-17 and therapeutic kynurenines in pathogenic inflammation to fungi. J Immunol. (2008) 180:5157–62. 10.4049/jimmunol.180.8.515718390695
-
(2008)
J Immunol
, vol.180
, pp. 5157-5162
-
-
Romani, L.1
Zelante, T.2
De Luca, A.3
Fallarino, F.4
Puccetti, P.5
-
22
-
-
84966526506
-
CARD9 impacts colitis by altering gut microbiota metabolism of tryptophan into aryl hydrocarbon receptor ligands
-
27158904
-
Lamas B, Richard ML, Leducq V, Pham HP, Michel ML, Da Costa G. CARD9 impacts colitis by altering gut microbiota metabolism of tryptophan into aryl hydrocarbon receptor ligands. Nat Med. (2016) 22:598–605. 10.1038/nm.410227158904
-
(2016)
Nat Med
, vol.22
, pp. 598-605
-
-
Lamas, B.1
Richard, M.L.2
Leducq, V.3
Pham, H.P.4
Michel, M.L.5
Da Costa, G.6
-
23
-
-
0020591879
-
Differential vulnerability of central neurons of the rat to quinolinic acid
-
6225037
-
Schwarcz R, Kohler C. Differential vulnerability of central neurons of the rat to quinolinic acid. Neurosci Lett. (1983) 38:85–90. 10.1016/0304-3940(83)90115-56225037
-
(1983)
Neurosci Lett
, vol.38
, pp. 85-90
-
-
Schwarcz, R.1
Kohler, C.2
-
24
-
-
33646856421
-
Bariatric surgery cannot prevent tryptophan depletion due to chronic immune activation in morbidly obese patients
-
16687019
-
Brandacher G, Winkler C, Aigner F, Schwelberger H, Schroecksnadel K, Margreiter R. Bariatric surgery cannot prevent tryptophan depletion due to chronic immune activation in morbidly obese patients. Obesity Surg. (2006) 16:541–8. 10.1381/09608920677694506616687019
-
(2006)
Obesity Surg
, vol.16
, pp. 541-548
-
-
Brandacher, G.1
Winkler, C.2
Aigner, F.3
Schwelberger, H.4
Schroecksnadel, K.5
Margreiter, R.6
-
25
-
-
84863888349
-
Tryptophan metabolism activation by indoleamine 2,3-dioxygenase in adipose tissue of obese women: an attempt to maintain immune homeostasis and vascular tone
-
22592557
-
Wolowczuk I, Hennart B, Leloire A, Bessede A, Soichot M, Taront S. Tryptophan metabolism activation by indoleamine 2,3-dioxygenase in adipose tissue of obese women: an attempt to maintain immune homeostasis and vascular tone. Am J Physiol Regul Integr Comp Physiol. (2012) 303:R135–43. 10.1152/ajpregu.00373.201122592557
-
(2012)
Am J Physiol Regul Integr Comp Physiol
, vol.303
, pp. R135-R143
-
-
Wolowczuk, I.1
Hennart, B.2
Leloire, A.3
Bessede, A.4
Soichot, M.5
Taront, S.6
-
26
-
-
84899833118
-
Disturbed tryptophan metabolism in cardiovascular disease
-
24606499
-
Mangge H, Stelzer I, Reininghaus EZ, Weghuber D, Postolache TT, Fuchs D. Disturbed tryptophan metabolism in cardiovascular disease. Curr Med Chem. (2014) 21:1931–7. 10.2174/092986732166614030410552624606499
-
(2014)
Curr Med Chem
, vol.21
, pp. 1931-1937
-
-
Mangge, H.1
Stelzer, I.2
Reininghaus, E.Z.3
Weghuber, D.4
Postolache, T.T.5
Fuchs, D.6
-
27
-
-
84942835576
-
The kynurenine pathway is activated in human obesity and shifted toward kynurenine monooxygenase activation
-
26347385
-
Favennec M, Hennart B, Caiazzo R, Leloire A, Yengo L, Verbanck M. The kynurenine pathway is activated in human obesity and shifted toward kynurenine monooxygenase activation. Obesity. (2015) 23:2066–74. 10.1002/oby.2119926347385
-
(2015)
Obesity
, vol.23
, pp. 2066-2074
-
-
Favennec, M.1
Hennart, B.2
Caiazzo, R.3
Leloire, A.4
Yengo, L.5
Verbanck, M.6
-
28
-
-
85048952408
-
Genetic deficiency of indoleamine 2,3-dioxygenase promotes gut microbiota-mediated metabolic health
-
29942089
-
Laurans L, Venteclef N, Haddad Y, Chajadine M, Alzaid F, Metghalchi S. Genetic deficiency of indoleamine 2,3-dioxygenase promotes gut microbiota-mediated metabolic health. Nat Med. (2018) 24:1113–20. 10.1038/s41591-018-0060-429942089
-
(2018)
Nat Med
, vol.24
, pp. 1113-1120
-
-
Laurans, L.1
Venteclef, N.2
Haddad, Y.3
Chajadine, M.4
Alzaid, F.5
Metghalchi, S.6
-
29
-
-
85044767398
-
Kynurenic acid and Gpr35 regulate adipose tissue energy homeostasis and inflammation
-
29414686
-
Agudelo LZ, Ferreira DMS, Cervenka I, Bryzgalova G, Dadvar S, Jannig PR. Kynurenic acid and Gpr35 regulate adipose tissue energy homeostasis and inflammation. Cell Metabol. (2018) 27:378–92 e5. 10.1016/j.cmet.2018.01.00429414686
-
(2018)
Cell Metabol
, vol.27
, pp. 378-370
-
-
Agudelo, L.Z.1
Ferreira, D.M.S.2
Cervenka, I.3
Bryzgalova, G.4
Dadvar, S.5
Jannig, P.R.6
-
30
-
-
85052715262
-
Loss of IDO1 expression from human pancreatic beta-cells precedes their destruction during the development of type 1 diabetes
-
29945890
-
Anquetil F, Mondanelli G, Gonzalez N, Rodriguez Calvo T, Zapardiel Gonzalo J, Krogvold L. Loss of IDO1 expression from human pancreatic beta-cells precedes their destruction during the development of type 1 diabetes. Diabetes. (2018) 67:1858–66. 10.2337/db17-128129945890
-
(2018)
Diabetes
, vol.67
, pp. 1858-1866
-
-
Anquetil, F.1
Mondanelli, G.2
Gonzalez, N.3
Rodriguez Calvo, T.4
Zapardiel Gonzalo, J.5
Krogvold, L.6
-
31
-
-
80052155097
-
Orally administered eicosapentaenoic acid induces rapid regression of atherosclerosis via modulating the phenotype of dendritic cells in LDL receptor-deficient mice
-
21817104
-
Nakajima K, Yamashita T, Kita T, Takeda M, Sasaki N, Kasahara K. Orally administered eicosapentaenoic acid induces rapid regression of atherosclerosis via modulating the phenotype of dendritic cells in LDL receptor-deficient mice. Arterioscler Thromb Vasc Biol. (2011) 31:1963–72. 10.1161/ATVBAHA.111.22944321817104
-
(2011)
Arterioscler Thromb Vasc Biol
, vol.31
, pp. 1963-1972
-
-
Nakajima, K.1
Yamashita, T.2
Kita, T.3
Takeda, M.4
Sasaki, N.5
Kasahara, K.6
-
32
-
-
84929070239
-
Inhibition of indoleamine 2,3-dioxygenase promotes vascular inflammation and increases atherosclerosis in Apoe–/– mice
-
Polyzos KA, Ovchinnikova O, Berg M, Baumgartner R, Agardh H, Pirault J. Inhibition of indoleamine 2,3-dioxygenase promotes vascular inflammation and increases atherosclerosis in Apoe–/– mice. Cardiovasc Res. (2015) 106:295–302. 10.1093/cvr/cvv100
-
(2015)
Cardiovasc Res
, vol.106
, pp. 295-302
-
-
Polyzos, K.A.1
Ovchinnikova, O.2
Berg, M.3
Baumgartner, R.4
Agardh, H.5
Pirault, J.6
-
33
-
-
84865210480
-
The tryptophan metabolite 3-hydroxyanthranilic acid lowers plasma lipids and decreases atherosclerosis in hypercholesterolaemic mice
-
22711758
-
Zhang L, Ovchinnikova O, Jonsson A, Lundberg AM, Berg M, Hansson GK. The tryptophan metabolite 3-hydroxyanthranilic acid lowers plasma lipids and decreases atherosclerosis in hypercholesterolaemic mice. Eur Heart J. (2012) 33:2025–34. 10.1093/eurheartj/ehs17522711758
-
(2012)
Eur Heart J
, vol.33
, pp. 2025-2034
-
-
Zhang, L.1
Ovchinnikova, O.2
Jonsson, A.3
Lundberg, A.M.4
Berg, M.5
Hansson, G.K.6
-
34
-
-
84947460330
-
Indoleamine 2,3-dioxygenase-1 is protective in atherosclerosis and its metabolites provide new opportunities for drug development
-
26438837
-
Cole JE, Astola N, Cribbs AP, Goddard ME, Park I, Green P. Indoleamine 2,3-dioxygenase-1 is protective in atherosclerosis and its metabolites provide new opportunities for drug development. Proc Natl Acad Sci USA. (2015) 112:13033–8. 10.1073/pnas.151782011226438837
-
(2015)
Proc Natl Acad Sci USA
, vol.112
, pp. 13033-13038
-
-
Cole, J.E.1
Astola, N.2
Cribbs, A.P.3
Goddard, M.E.4
Park, I.5
Green, P.6
-
35
-
-
84940720318
-
Indoleamine 2,3-dioxygenase fine-tunes immune homeostasis in atherosclerosis and colitis through repression of interleukin-10 production
-
26235422
-
Metghalchi S, Ponnuswamy P, Simon T, Haddad Y, Laurans L, Clement M. Indoleamine 2,3-dioxygenase fine-tunes immune homeostasis in atherosclerosis and colitis through repression of interleukin-10 production. Cell Metabol. (2015) 22:460–71. 10.1016/j.cmet.2015.07.00426235422
-
(2015)
Cell Metabol
, vol.22
, pp. 460-471
-
-
Metghalchi, S.1
Ponnuswamy, P.2
Simon, T.3
Haddad, Y.4
Laurans, L.5
Clement, M.6
-
36
-
-
0033569130
-
Protective role of interleukin-10 in atherosclerosis
-
10521249
-
Mallat Z, Besnard S, Duriez M, Deleuze V, Emmanuel F, Bureau MF. Protective role of interleukin-10 in atherosclerosis. Circ Res. (1999) 85:e17–24. 10.1161/01.RES.85.8.e1710521249
-
(1999)
Circ Res
, vol.85
, pp. e17-e24
-
-
Mallat, Z.1
Besnard, S.2
Duriez, M.3
Deleuze, V.4
Emmanuel, F.5
Bureau, M.F.6
-
37
-
-
84904216760
-
Aryl hydrocarbon receptor control of a disease tolerance defence pathway
-
24930766
-
Bessede A, Gargaro M, Pallotta MT, Matino D, Servillo G, Brunacci C. Aryl hydrocarbon receptor control of a disease tolerance defence pathway. Nature. (2014) 511:184–90. 10.1038/nature1332324930766
-
(2014)
Nature
, vol.511
, pp. 184-190
-
-
Bessede, A.1
Gargaro, M.2
Pallotta, M.T.3
Matino, D.4
Servillo, G.5
Brunacci, C.6
-
38
-
-
85044303941
-
Regulation of the immune response by the aryl hydrocarbon receptor
-
29343438
-
Gutierrez-Vazquez C, Quintana FJ. Regulation of the immune response by the aryl hydrocarbon receptor. Immunity. (2018) 48:19–33. 10.1016/j.immuni.2017.12.01229343438
-
(2018)
Immunity
, vol.48
, pp. 19-33
-
-
Gutierrez-Vazquez, C.1
Quintana, F.J.2
-
39
-
-
33847616039
-
Indoleamine 2,3-dioxygenase enzyme activity correlates with risk factors for atherosclerosis: the cardiovascular risk in young finns study
-
17349013
-
Pertovaara M, Raitala A, Juonala M, Lehtimaki T, Huhtala H, Oja SS. Indoleamine 2,3-dioxygenase enzyme activity correlates with risk factors for atherosclerosis: the cardiovascular risk in young finns study. Clin Exp Immunol. (2007) 148:106–11. 10.1111/j.1365-2249.2007.03325.x17349013
-
(2007)
Clin Exp Immunol
, vol.148
, pp. 106-111
-
-
Pertovaara, M.1
Raitala, A.2
Juonala, M.3
Lehtimaki, T.4
Huhtala, H.5
Oja, S.S.6
-
40
-
-
57349088307
-
Indoleamine 2,3-dioxygenase activity associates with cardiovascular risk factors: the health 2000 study
-
18622801
-
Niinisalo P, Raitala A, Pertovaara M, Oja SS, Lehtimaki T, Kahonen M. Indoleamine 2,3-dioxygenase activity associates with cardiovascular risk factors: the health 2000 study. Scand J Clin Lab Invest. (2008) 68:767–70. 10.1080/0036551080224568518622801
-
(2008)
Scand J Clin Lab Invest
, vol.68
, pp. 767-770
-
-
Niinisalo, P.1
Raitala, A.2
Pertovaara, M.3
Oja, S.S.4
Lehtimaki, T.5
Kahonen, M.6
-
41
-
-
79952194201
-
Systemic markers of interferon-gamma-mediated immune activation and long-term prognosis in patients with stable coronary artery disease
-
21183733
-
Pedersen ER, Midttun O, Ueland PM, Schartum-Hansen H, Seifert R, Igland J. Systemic markers of interferon-gamma-mediated immune activation and long-term prognosis in patients with stable coronary artery disease. Arterioscler Thromb Vasc Biol. (2011) 31:698–704. 10.1161/ATVBAHA.110.21932921183733
-
(2011)
Arterioscler Thromb Vasc Biol
, vol.31
, pp. 698-704
-
-
Pedersen, E.R.1
Midttun, O.2
Ueland, P.M.3
Schartum-Hansen, H.4
Seifert, R.5
Igland, J.6
-
42
-
-
84929172773
-
Kynurenines as predictors of acute coronary events in the hordaland health study
-
25885868
-
Eussen SJ, Ueland PM, Vollset SE, Nygard O, Midttun O, Sulo G. Kynurenines as predictors of acute coronary events in the hordaland health study. Int J Cardiol. (2015) 189:18–24. 10.1016/j.ijcard.2015.03.41325885868
-
(2015)
Int J Cardiol
, vol.189
, pp. 18-24
-
-
Eussen, S.J.1
Ueland, P.M.2
Vollset, S.E.3
Nygard, O.4
Midttun, O.5
Sulo, G.6
-
43
-
-
84922022406
-
Associations of plasma kynurenines with risk of acute myocardial infarction in patients with stable angina pectoris
-
25524770
-
Pedersen ER, Tuseth N, Eussen SJ, Ueland PM, Strand E, Svingen GF. Associations of plasma kynurenines with risk of acute myocardial infarction in patients with stable angina pectoris. Arterioscler Thromb Vasc Biol. (2015) 35:455–62. 10.1161/ATVBAHA.114.30467425524770
-
(2015)
Arterioscler Thromb Vasc Biol
, vol.35
, pp. 455-462
-
-
Pedersen, E.R.1
Tuseth, N.2
Eussen, S.J.3
Ueland, P.M.4
Strand, E.5
Svingen, G.F.6
-
44
-
-
62649151803
-
Metabolomics analysis reveals large effects of gut microflora on mammalian blood metabolites
-
19234110
-
Wikoff WR, Anfora AT, Liu J, Schultz PG, Lesley SA, Peters EC. Metabolomics analysis reveals large effects of gut microflora on mammalian blood metabolites. Proc Natl Acad Sci USA. (2009) 106:3698–703. 10.1073/pnas.081287410619234110
-
(2009)
Proc Natl Acad Sci USA
, vol.106
, pp. 3698-3703
-
-
Wikoff, W.R.1
Anfora, A.T.2
Liu, J.3
Schultz, P.G.4
Lesley, S.A.5
Peters, E.C.6
-
45
-
-
85059927367
-
Butyrate produced by commensal bacteria down-regulates indolamine 2,3-dioxygenase 1 (IDO-1) expression via a dual mechanism in human intestinal epithelial cells
-
30619249
-
Martin-Gallausiaux C, Larraufie P, Jarry A, Beguet-Crespel F, Marinelli L, Ledue F. Butyrate produced by commensal bacteria down-regulates indolamine 2,3-dioxygenase 1 (IDO-1) expression via a dual mechanism in human intestinal epithelial cells. Front Immunol. (2018) 9:2838. 10.3389/fimmu.2018.0283830619249
-
(2018)
Front Immunol
, vol.9
, pp. 2838
-
-
Martin-Gallausiaux, C.1
Larraufie, P.2
Jarry, A.3
Beguet-Crespel, F.4
Marinelli, L.5
Ledue, F.6
-
46
-
-
84878241830
-
The microbiome–gut–brain axis during early life regulates the hippocampal serotonergic system in a sex-dependent manner
-
22688187
-
Clarke G, Grenham S, Scully P, Fitzgerald P, Moloney RD, Shanahan F. The microbiome–gut–brain axis during early life regulates the hippocampal serotonergic system in a sex-dependent manner. Mol Psychiatry. (2013) 18:666–73. 10.1038/mp.2012.7722688187
-
(2013)
Mol Psychiatry
, vol.18
, pp. 666-673
-
-
Clarke, G.1
Grenham, S.2
Scully, P.3
Fitzgerald, P.4
Moloney, R.D.5
Shanahan, F.6
-
47
-
-
85056004239
-
Impaired aryl hydrocarbon receptor ligand production by the gut microbiota is a key factor in metabolic syndrome
-
30057068
-
Natividad JM, Agus A, Planchais J, Lamas B, Jarry AC, Martin R. Impaired aryl hydrocarbon receptor ligand production by the gut microbiota is a key factor in metabolic syndrome. Cell Metabol. (2018) 28:737–49 e4. 10.1016/j.cmet.2018.07.00130057068
-
(2018)
Cell Metabol
, vol.28
, pp. 737-730
-
-
Natividad, J.M.1
Agus, A.2
Planchais, J.3
Lamas, B.4
Jarry, A.C.5
Martin, R.6
-
48
-
-
84919478013
-
Tryptophan feeding of the IDO1–AhR axis in host–microbial symbiosis
-
25566253
-
Zelante T, Iannitti RG, Fallarino F, Gargaro M, De Luca A, Moretti S. Tryptophan feeding of the IDO1–AhR axis in host–microbial symbiosis. Front Immunol. (2014) 5:640. 10.3389/fimmu.2014.0064025566253
-
(2014)
Front Immunol
, vol.5
, pp. 640
-
-
Zelante, T.1
Iannitti, R.G.2
Fallarino, F.3
Gargaro, M.4
De Luca, A.5
Moretti, S.6
-
49
-
-
84908311821
-
Interleukin-22 alleviates metabolic disorders and restores mucosal immunity in diabetes
-
25119041
-
Wang X, Ota N, Manzanillo P, Kates L, Zavala-Solorio J, Eidenschenk C. Interleukin-22 alleviates metabolic disorders and restores mucosal immunity in diabetes. Nature. (2014) 514:237–41. 10.1038/nature1356425119041
-
(2014)
Nature
, vol.514
, pp. 237-241
-
-
Wang, X.1
Ota, N.2
Manzanillo, P.3
Kates, L.4
Zavala-Solorio, J.5
Eidenschenk, C.6
-
50
-
-
85056320549
-
An interleukin-23–interleukin-22 axis regulates intestinal microbial homeostasis to protect from diet-induced atherosclerosis
-
30389414
-
Fatkhullina AR, Peshkova IO, Dzutsev A, Aghayev T, McCulloch JA, Thovarai V. An interleukin-23–interleukin-22 axis regulates intestinal microbial homeostasis to protect from diet-induced atherosclerosis. Immunity. (2018) 49:943–57 e9. 10.1016/j.immuni.2018.09.01130389414
-
(2018)
Immunity
, vol.49
, pp. 943-940
-
-
Fatkhullina, A.R.1
Peshkova, I.O.2
Dzutsev, A.3
Aghayev, T.4
McCulloch, J.A.5
Thovarai, V.6
-
51
-
-
84907597269
-
Symbiotic bacterial metabolites regulate gastrointestinal barrier function via the xenobiotic sensor PXR and Toll-like receptor 4
-
25065623
-
Venkatesh M, Mukherjee S, Wang H, Li H, Sun K, Benechet AP. Symbiotic bacterial metabolites regulate gastrointestinal barrier function via the xenobiotic sensor PXR and Toll-like receptor 4. Immunity. (2014) 41:296–310. 10.1016/j.immuni.2014.06.01425065623
-
(2014)
Immunity
, vol.41
, pp. 296-310
-
-
Venkatesh, M.1
Mukherjee, S.2
Wang, H.3
Li, H.4
Sun, K.5
Benechet, A.P.6
-
52
-
-
84923212941
-
Inhibiting peripheral serotonin synthesis reduces obesity and metabolic dysfunction by promoting brown adipose tissue thermogenesis
-
25485911
-
Crane JD, Palanivel R, Mottillo EP, Bujak AL, Wang H, Ford RJ. Inhibiting peripheral serotonin synthesis reduces obesity and metabolic dysfunction by promoting brown adipose tissue thermogenesis. Nat Med. (2015) 21:166–72. 10.1038/nm.376625485911
-
(2015)
Nat Med
, vol.21
, pp. 166-172
-
-
Crane, J.D.1
Palanivel, R.2
Mottillo, E.P.3
Bujak, A.L.4
Wang, H.5
Ford, R.J.6
-
53
-
-
85053681460
-
Indoles—Gut bacteria metabolites of tryptophan with pharmacotherapeutic potential
-
29708069
-
Konopelski P, Ufnal M. Indoles—Gut bacteria metabolites of tryptophan with pharmacotherapeutic potential. Curr Drug Metabol. (2018) 19:883–90 10.2174/138920021966618042716473129708069
-
(2018)
Curr Drug Metabol
, vol.19
, pp. 883-890
-
-
Konopelski, P.1
Ufnal, M.2
-
54
-
-
85021811792
-
Indoleacrylic acid produced by commensal peptostreptococcus species suppresses inflammation
-
28704649
-
Wlodarska M, Luo C, Kolde R, d'Hennezel E, Annand JW, Heim CE. Indoleacrylic acid produced by commensal peptostreptococcus species suppresses inflammation. Cell Host Microbe. (2017) 22:25–37.e6. 10.1016/j.chom.2017.06.00728704649
-
(2017)
Cell Host Microbe
, vol.22
, pp. 25-37
-
-
Wlodarska, M.1
Luo, C.2
Kolde, R.3
d'Hennezel, E.4
Annand, J.W.5
Heim, C.E.6
-
55
-
-
84912137874
-
Bacterial metabolite indole modulates incretin secretion from intestinal enteroendocrine L cells
-
25456122
-
Chimerel C, Emery E, Summers DK, Keyser U, Gribble FM, Reimann F. Bacterial metabolite indole modulates incretin secretion from intestinal enteroendocrine L cells. Cell Rep. (2014) 9:1202–8. 10.1016/j.celrep.2014.10.03225456122
-
(2014)
Cell Rep
, vol.9
, pp. 1202-1208
-
-
Chimerel, C.1
Emery, E.2
Summers, D.K.3
Keyser, U.4
Gribble, F.M.5
Reimann, F.6
-
56
-
-
85055470325
-
The gut microbiota metabolite indole alleviates liver inflammation in mice
-
Beaumont M, Neyrinck AM, Olivares M, Rodriguez J, de Rocca Serra A, Roumain M. The gut microbiota metabolite indole alleviates liver inflammation in mice. FASEB J. (2018) 32:fj201800544. 10.1096/fj.201800544
-
(2018)
FASEB J
, vol.32
-
-
Beaumont, M.1
Neyrinck, A.M.2
Olivares, M.3
Rodriguez, J.4
de Rocca Serra, A.5
Roumain, M.6
|