Orally administered eicosapentaenoic acid induces rapid regression of atherosclerosis via modulating the phenotype of dendritic cells in LDL receptor-deficient mice

Arteriosclerosis, Thrombosis, and Vascular Biology

Volumn 31, Issue 9, 2011, Pages 1963-1972

  Nakajima, Kenji ^a   Yamashita, Tomoya ^a   Kita, Tomoyuki ^a   Takeda, Masafumi ^a   Sasaki, Naoto ^a,b   Kasahara, Kazuyuki ^a   Shinohara, Masakazu ^a   Rikitake, Yoshiyuki ^a   Ishida, Tatsuro ^a   Yokoyama, Mitsuhiro ^a,c   Hirata, Ken Ichi ^a  

^a KOBE UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

^b KYOTO UNIVERSITY   (Japan)

^c Hyogo Brain and Heart Center   (Japan)

Author keywords

Atherosclerosis; dendritic cells; Immune system; lymphocytes; regression

Indexed keywords

B7 ANTIGEN; CD40 ANTIGEN; CD86 ANTIGEN; CHOLESTEROL; GAMMA INTERFERON; GELATINASE A; GELATINASE B; GLYCOPROTEIN P 15095; HERMES ANTIGEN; HIGH DENSITY LIPOPROTEIN CHOLESTEROL; ICOSAPENTAENOIC ACID; INDOLEAMINE 2,3 DIOXYGENASE; INDOLEAMINE 2,3 DIOXYGENASE INHIBITOR; INTERCELLULAR ADHESION MOLECULE 1; INTERLEUKIN 10; INTERLEUKIN 12P40; INTERLEUKIN 17; INTERLEUKIN 4; L SELECTIN; LOW DENSITY LIPOPROTEIN RECEPTOR; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 2; MONOCYTE CHEMOTACTIC PROTEIN 1; TRANSCRIPTION FACTOR FOXP3; TRANSFORMING GROWTH FACTOR BETA; TRIACYLGLYCEROL; TUMOR NECROSIS FACTOR ALPHA; VASCULAR CELL ADHESION MOLECULE 1;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; AORTA ATHEROSCLEROSIS; AORTA SINUS; ARTICLE; ATHEROSCLEROSIS; ATHEROSCLEROTIC PLAQUE; CD4 LYMPHOCYTE COUNT; CHOLESTEROL BLOOD LEVEL; CHOLESTEROL DIET; CONTROLLED STUDY; CYTOKINE PRODUCTION; DENDRITIC CELL; DRUG EFFECT; DRUG MECHANISM; FLOW CYTOMETRY; GENE EXPRESSION; IMMUNOASSAY; IMMUNOMODULATION; LYMPH NODE; LYMPHOCYTE FUNCTION; MACROPHAGE; MALE; MOUSE; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; SPLEEN; TRIACYLGLYCEROL BLOOD LEVEL;

ADMINISTRATION, ORAL; ANIMALS; ATHEROSCLEROSIS; CYTOKINES; DENDRITIC CELLS; EICOSAPENTAENOIC ACID; INDOLEAMINE-PYRROLE 2,3,-DIOXYGENASE; MALE; MICE; PHENOTYPE; RECEPTORS, LDL; RNA, MESSENGER; T-LYMPHOCYTES;

EID: 80052155097     PISSN: 10795642     EISSN: 15244636     Source Type: Journal    
DOI: 10.1161/ATVBAHA.111.229443     Document Type: Article

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