The Pleiotropic Effects of Sodium–Glucose Cotransporter-2 Inhibitors: Beyond the Glycemic Benefit

Diabetes Therapy

Volumn 10, Issue 5, 2019, Pages 1771-1792

  Patel, Dhiren K ^a   Strong, Jodi ^b  

^a VA BOSTON HEALTHCARE SYSTEM   (United States)

^b Ascension Medical Group   (United States)

Author keywords

Cardiovascular disease; Chronic kidney disease; Pleiotropic effects; Sodium glucose cotransporter 2 inhibitors; Type 2 diabetes

Indexed keywords

CANAGLIFLOZIN; DAPAGLIFLOZIN; EMPAGLIFLOZIN; ERTUGLIFLOZIN; HIGH DENSITY LIPOPROTEIN CHOLESTEROL; LOW DENSITY LIPOPROTEIN CHOLESTEROL; SODIUM GLUCOSE COTRANSPORTER 2 INHIBITOR; SOTAGLIFLOZIN;

ADVERSE OUTCOME; ALL CAUSE MORTALITY; BLOOD PRESSURE MONITORING; BODY WEIGHT; CARDIOVASCULAR DISEASE; CARDIOVASCULAR MORTALITY; CHRONIC KIDNEY FAILURE; DIABETIC NEPHROPATHY; DRUG SAFETY; ESTIMATED GLOMERULAR FILTRATION RATE; GLOMERULUS FILTRATION RATE; GLUCAGON RELEASE; GLUCOSE BLOOD LEVEL; GLUCOSE HOMEOSTASIS; GLYCEMIC CONTROL; HEART FAILURE; HEART FUNCTION; HEART VENTRICLE REMODELING; HEMODYNAMICS; HOSPITALIZATION; HUMAN; HYPERGLYCEMIA; INCIDENCE; KIDNEY BLOOD FLOW; META ANALYSIS (TOPIC); NON INSULIN DEPENDENT DIABETES MELLITUS; PHASE 3 CLINICAL TRIAL (TOPIC); PLEIOTROPY; POSTMARKETING SURVEILLANCE; PRIORITY JOURNAL; RANDOMIZED CONTROLLED TRIAL (TOPIC); RENAL REPLACEMENT THERAPY; REVIEW; RISK ASSESSMENT; RISK FACTOR; ULTRAFILTRATION;

EID: 85071834846     PISSN: 18696953     EISSN: 18696961     Source Type: Journal    
DOI: 10.1007/s13300-019-00686-z     Document Type: Review

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