-
1
-
-
67749129442
-
-
Accessed 05 February 2018
-
World Health Organization. Obesity and overweight fact sheet. 2017. http://www.who.int/mediacentre/factsheets/fs311/en/. Accessed 05 February 2018.
-
(2017)
Obesity and Overweight Fact Sheet
-
-
-
2
-
-
84946475074
-
Comorbidity associated with obesity in a large population: the APNA study
-
Martin-Rodriguez E, Guillen-Grima F, Marti A, Brugos-Larumbe A. Comorbidity associated with obesity in a large population: the APNA study. Obesity research & clinical practice. 2015;9(5):435–47.
-
(2015)
Obesity research & clinical practice.
, vol.9
, Issue.5
, pp. 435-447
-
-
Martin-Rodriguez, E.1
Guillen-Grima, F.2
Marti, A.3
Brugos-Larumbe, A.4
-
3
-
-
84958632559
-
Patients with obesity-related comorbidities have higher disability compared with those without obesity-related comorbidities: results from a cross-sectional study
-
PID: 26579698
-
Sirtori A, Brunani A, Capodaglio P, Berselli ME, Villa V, Ceriani F, et al. Patients with obesity-related comorbidities have higher disability compared with those without obesity-related comorbidities: results from a cross-sectional study. Int J Rehabil Res. 2016;39(1):63–9.
-
(2016)
Int J Rehabil Res
, vol.39
, Issue.1
, pp. 63-69
-
-
Sirtori, A.1
Brunani, A.2
Capodaglio, P.3
Berselli, M.E.4
Villa, V.5
Ceriani, F.6
-
4
-
-
33745684406
-
Association between obesity and psychiatric disorders in the US adult population
-
PID: 16818872
-
Simon GE, Von Korff M, Saunders K, Miglioretti DL, Crane PK, van Belle G, et al. Association between obesity and psychiatric disorders in the US adult population. Arch Gen Psychiatry. 2006;63(7):824–30.
-
(2006)
Arch Gen Psychiatry
, vol.63
, Issue.7
, pp. 824-830
-
-
Simon, G.E.1
Von Korff, M.2
Saunders, K.3
Miglioretti, D.L.4
Crane, P.K.5
van Belle, G.6
-
5
-
-
33749616411
-
The medical complications of obesity
-
PID: 16916862
-
Malnick SD, Knobler H. The medical complications of obesity. QJM. 2006;99(9):565–79.
-
(2006)
QJM
, vol.99
, Issue.9
, pp. 565-579
-
-
Malnick, S.D.1
Knobler, H.2
-
6
-
-
0037034257
-
Reduction in the incidence of type 2 diabetes with lifestyle intervention or metformin
-
PID: 11832527
-
Knowler WC, Barrett-Connor E, Fowler SE, Hamman RF, Lachin JM, Walker EA, et al. Reduction in the incidence of type 2 diabetes with lifestyle intervention or metformin. N Engl J Med. 2002;346(6):393–403.
-
(2002)
N Engl J Med
, vol.346
, Issue.6
, pp. 393-403
-
-
Knowler, W.C.1
Barrett-Connor, E.2
Fowler, S.E.3
Hamman, R.F.4
Lachin, J.M.5
Walker, E.A.6
-
7
-
-
85037040997
-
Primary care-led weight management for remission of type 2 diabetes (DiRECT): an open-label, cluster-randomised trial
-
PID: 29221645
-
Lean ME, Leslie WS, Barnes AC, Brosnahan N, Thom G, McCombie L, et al. Primary care-led weight management for remission of type 2 diabetes (DiRECT): an open-label, cluster-randomised trial. Lancet. 2018;391(10120):541–51.
-
(2018)
Lancet
, vol.391
, Issue.10120
, pp. 541-551
-
-
Lean, M.E.1
Leslie, W.S.2
Barnes, A.C.3
Brosnahan, N.4
Thom, G.5
McCombie, L.6
-
8
-
-
0345707499
-
The Finnish Diabetes Prevention Study (DPS): lifestyle intervention and 3-year results on diet and physical activity
-
PID: 14633807
-
Lindstrom J, Louheranta A, Mannelin M, Rastas M, Salminen V, Eriksson J, et al. The Finnish Diabetes Prevention Study (DPS): lifestyle intervention and 3-year results on diet and physical activity. Diabetes Care. 2003;26(12):3230–6.
-
(2003)
Diabetes Care
, vol.26
, Issue.12
, pp. 3230-3236
-
-
Lindstrom, J.1
Louheranta, A.2
Mannelin, M.3
Rastas, M.4
Salminen, V.5
Eriksson, J.6
-
9
-
-
84855367738
-
Bariatric surgery and long-term cardiovascular events
-
PID: 22215166
-
Sjostrom L, Peltonen M, Jacobson P, Sjostrom CD, Karason K, Wedel H, et al. Bariatric surgery and long-term cardiovascular events. JAMA. 2012;307(1):56–65.
-
(2012)
JAMA
, vol.307
, Issue.1
, pp. 56-65
-
-
Sjostrom, L.1
Peltonen, M.2
Jacobson, P.3
Sjostrom, C.D.4
Karason, K.5
Wedel, H.6
-
10
-
-
67649344115
-
Effects of bariatric surgery on cancer incidence in obese patients in Sweden (Swedish Obese Subjects Study): a prospective, controlled intervention trial
-
PID: 19556163
-
Sjostrom L, Gummesson A, Sjostrom CD, Narbro K, Peltonen M, Wedel H, et al. Effects of bariatric surgery on cancer incidence in obese patients in Sweden (Swedish Obese Subjects Study): a prospective, controlled intervention trial. Lancet Oncol. 2009;10(7):653–62.
-
(2009)
Lancet Oncol.
, vol.10
, Issue.7
, pp. 653-662
-
-
Sjostrom, L.1
Gummesson, A.2
Sjostrom, C.D.3
Narbro, K.4
Peltonen, M.5
Wedel, H.6
-
11
-
-
34548090763
-
Effects of bariatric surgery on mortality in Swedish obese subjects
-
PID: 17715408
-
Sjostrom L, Narbro K, Sjostrom CD, Karason K, Larsson B, Wedel H, et al. Effects of bariatric surgery on mortality in Swedish obese subjects. N Engl J Med. 2007;357(8):741–52.
-
(2007)
N Engl J Med
, vol.357
, Issue.8
, pp. 741-752
-
-
Sjostrom, L.1
Narbro, K.2
Sjostrom, C.D.3
Karason, K.4
Larsson, B.5
Wedel, H.6
-
12
-
-
85035076386
-
Combination therapy for obesity
-
PID: 29132230
-
Wilding JP. Combination therapy for obesity. J Psychopharmacol. 2017;31(11):1503–8.
-
(2017)
J Psychopharmacol.
, vol.31
, Issue.11
, pp. 1503-1508
-
-
Wilding, J.P.1
-
13
-
-
84891865819
-
Characterization of renal glucose reabsorption in response to dapagliflozin in healthy subjects and subjects with type 2 diabetes
-
PID: 23735727
-
DeFronzo RA, Hompesch M, Kasichayanula S, Liu X, Hong Y, Pfister M, et al. Characterization of renal glucose reabsorption in response to dapagliflozin in healthy subjects and subjects with type 2 diabetes. Diabetes Care. 2013;36(10):3169–76.
-
(2013)
Diabetes Care
, vol.36
, Issue.10
, pp. 3169-3176
-
-
DeFronzo, R.A.1
Hompesch, M.2
Kasichayanula, S.3
Liu, X.4
Hong, Y.5
Pfister, M.6
-
14
-
-
84997124377
-
Efficacy and Tolerability of Exenatide Once Weekly Over 6 Years in Patients with Type 2 Diabetes: an Uncontrolled Open-Label Extension of the DURATION-1 Study
-
PID: 27525540
-
Henry RR, Klein EJ, Han J, Iqbal N. Efficacy and Tolerability of Exenatide Once Weekly Over 6 Years in Patients with Type 2 Diabetes: an Uncontrolled Open-Label Extension of the DURATION-1 Study. Diabetes Technol Ther. 2016;18(11):677–86.
-
(2016)
Diabetes Technol Ther.
, vol.18
, Issue.11
, pp. 677-686
-
-
Henry, R.R.1
Klein, E.J.2
Han, J.3
Iqbal, N.4
-
15
-
-
84892479365
-
Dapagliflozin maintains glycaemic control while reducing weight and body fat mass over 2 years in patients with type 2 diabetes mellitus inadequately controlled on metformin
-
PID: 23906445
-
Bolinder J, Ljunggren O, Johansson L, Wilding J, Langkilde AM, Sjostrom CD, et al. Dapagliflozin maintains glycaemic control while reducing weight and body fat mass over 2 years in patients with type 2 diabetes mellitus inadequately controlled on metformin. Diabetes Obes Metab. 2014;16(2):159–69.
-
(2014)
Diabetes Obes Metab
, vol.16
, Issue.2
, pp. 159-169
-
-
Bolinder, J.1
Ljunggren, O.2
Johansson, L.3
Wilding, J.4
Langkilde, A.M.5
Sjostrom, C.D.6
-
16
-
-
84928426587
-
Long-term glycaemic response and tolerability of dapagliflozin versus a sulphonylurea as add-on therapy to metformin in patients with type 2 diabetes: 4-year data
-
PID: 25735400
-
Del Prato S, Nauck M, Duran-Garcia S, Maffei L, Rohwedder K, Theuerkauf A, et al. Long-term glycaemic response and tolerability of dapagliflozin versus a sulphonylurea as add-on therapy to metformin in patients with type 2 diabetes: 4-year data. Diabetes Obes Metab. 2015;17(6):581–90.
-
(2015)
Diabetes Obes Metab
, vol.17
, Issue.6
, pp. 581-590
-
-
Del Prato, S.1
Nauck, M.2
Duran-Garcia, S.3
Maffei, L.4
Rohwedder, K.5
Theuerkauf, A.6
-
17
-
-
84994508611
-
Exenatide once weekly plus dapagliflozin once daily versus exenatide or dapagliflozin alone in patients with type 2 diabetes inadequately controlled with metformin monotherapy (DURATION-8): a 28 week, multicentre, double-blind, phase 3, randomised controlled trial
-
Frias JP, Guja C, Hardy E, Ahmed A, Dong F, Ohman P, et al. Exenatide once weekly plus dapagliflozin once daily versus exenatide or dapagliflozin alone in patients with type 2 diabetes inadequately controlled with metformin monotherapy (DURATION-8): a 28 week, multicentre, double-blind, phase 3, randomised controlled trial. The lancet Diabetes & endocrinology. 2016;4(12):1004–16.
-
(2016)
The lancet Diabetes & endocrinology.
, vol.4
, Issue.12
, pp. 1004-1016
-
-
Frias, J.P.1
Guja, C.2
Hardy, E.3
Ahmed, A.4
Dong, F.5
Ohman, P.6
-
18
-
-
84955304504
-
Benefits and Harms of Once-Weekly Glucagon-like Peptide-1 Receptor Agonist Treatments: a Systematic Review and Network Meta-analysis
-
PID: 26642233
-
Zaccardi F, Htike ZZ, Webb DR, Khunti K, Davies MJ. Benefits and Harms of Once-Weekly Glucagon-like Peptide-1 Receptor Agonist Treatments: a Systematic Review and Network Meta-analysis. Ann Intern Med. 2016;164(2):102–13.
-
(2016)
Ann Intern Med
, vol.164
, Issue.2
, pp. 102-113
-
-
Zaccardi, F.1
Htike, Z.Z.2
Webb, D.R.3
Khunti, K.4
Davies, M.J.5
-
19
-
-
84938718347
-
The Effect of Glucagon-Like Peptide 1 Receptor Agonists on Weight Loss in Type 2 Diabetes: a Systematic Review and Mixed Treatment Comparison Meta-Analysis
-
PID: 26121478
-
Potts JE, Gray LJ, Brady EM, Khunti K, Davies MJ, Bodicoat DH. The Effect of Glucagon-Like Peptide 1 Receptor Agonists on Weight Loss in Type 2 Diabetes: a Systematic Review and Mixed Treatment Comparison Meta-Analysis. PLoS ONE. 2015;10(6):e0126769.
-
(2015)
PLoS ONE
, vol.10
, Issue.6
-
-
Potts, J.E.1
Gray, L.J.2
Brady, E.M.3
Khunti, K.4
Davies, M.J.5
Bodicoat, D.H.6
-
20
-
-
84960433486
-
SGLT-2 receptor inhibitors for treating patients with type 2 diabetes mellitus: a systematic review and network meta-analysis
-
PID: 26911584
-
Shyangdan DS, Uthman OA, Waugh N. SGLT-2 receptor inhibitors for treating patients with type 2 diabetes mellitus: a systematic review and network meta-analysis. BMJ Open. 2016;6(2):e009417.
-
(2016)
BMJ Open
, vol.6
, Issue.2
-
-
Shyangdan, D.S.1
Uthman, O.A.2
Waugh, N.3
-
21
-
-
85020067582
-
Dapagliflozin once daily plus exenatide once weekly in obese adults without diabetes: sustained reductions in bodyweight, glycaemia, and blood pressure over 1 year
-
Lundkvist P, Pereira MJ, Katsogiannos P, Sjostrom CD, Johnsson E, Eriksson JW. Dapagliflozin once daily plus exenatide once weekly in obese adults without diabetes: sustained reductions in bodyweight, glycaemia, and blood pressure over 1 year. Diabetes Obes Metab. 2017.
-
(2017)
Diabetes Obes Metab
-
-
Lundkvist, P.1
Pereira, M.J.2
Katsogiannos, P.3
Sjostrom, C.D.4
Johnsson, E.5
Eriksson, J.W.6
-
22
-
-
84983094627
-
Efficacy and safety of antihyperglycaemic drug regimens added to metformin and sulphonylurea therapy in Type 2 diabetes: a network meta-analysis
-
PID: 26104021
-
Mearns ES, Saulsberry WJ, White CM, Kohn CG, Lemieux S, Sihabout A, et al. Efficacy and safety of antihyperglycaemic drug regimens added to metformin and sulphonylurea therapy in Type 2 diabetes: a network meta-analysis. Diabet Med. 2015;32(12):1530–40.
-
(2015)
Diabet Med
, vol.32
, Issue.12
, pp. 1530-1540
-
-
Mearns, E.S.1
Saulsberry, W.J.2
White, C.M.3
Kohn, C.G.4
Lemieux, S.5
Sihabout, A.6
-
24
-
-
85021428641
-
Combination SGLT2 inhibitor and GLP-1 receptor agonist therapy: a complementary approach to the treatment of type 2 diabetes
-
PID: 28657399
-
Busch RS, Kane MP. Combination SGLT2 inhibitor and GLP-1 receptor agonist therapy: a complementary approach to the treatment of type 2 diabetes. Postgrad Med. 2017;129(7):686–97.
-
(2017)
Postgrad Med
, vol.129
, Issue.7
, pp. 686-697
-
-
Busch, R.S.1
Kane, M.P.2
-
25
-
-
84882251091
-
Sodium-glucose cotransporter 2 inhibitors for type 2 diabetes: a systematic review and meta-analysis
-
PID: 24026259
-
Vasilakou D, Karagiannis T, Athanasiadou E, Mainou M, Liakos A, Bekiari E, et al. Sodium-glucose cotransporter 2 inhibitors for type 2 diabetes: a systematic review and meta-analysis. Ann Intern Med. 2013;159(4):262–74.
-
(2013)
Ann Intern Med
, vol.159
, Issue.4
, pp. 262-274
-
-
Vasilakou, D.1
Karagiannis, T.2
Athanasiadou, E.3
Mainou, M.4
Liakos, A.5
Bekiari, E.6
-
26
-
-
84969915634
-
Efficacy and safety of sodium-glucose co-transporter-2 inhibitors in type 2 diabetes mellitus: systematic review and network meta-analysis
-
PID: 27059700
-
Zaccardi F, Webb DR, Htike ZZ, Youssef D, Khunti K, Davies MJ. Efficacy and safety of sodium-glucose co-transporter-2 inhibitors in type 2 diabetes mellitus: systematic review and network meta-analysis. Diabetes Obes Metab. 2016;18(8):783–94.
-
(2016)
Diabetes Obes Metab
, vol.18
, Issue.8
, pp. 783-794
-
-
Zaccardi, F.1
Webb, D.R.2
Htike, Z.Z.3
Youssef, D.4
Khunti, K.5
Davies, M.J.6
-
27
-
-
84948716657
-
Efficacy and safety of sodium-glucose cotransporter 2 inhibitors in type 2 diabetes: a meta-analysis of randomized controlled trials for 1 to 2years
-
PID: 26365905
-
Liu XY, Zhang N, Chen R, Zhao JG, Yu P. Efficacy and safety of sodium-glucose cotransporter 2 inhibitors in type 2 diabetes: a meta-analysis of randomized controlled trials for 1 to 2years. J Diabetes Complications. 2015;29(8):1295–303.
-
(2015)
J Diabetes Complications
, vol.29
, Issue.8
, pp. 1295-1303
-
-
Liu, X.Y.1
Zhang, N.2
Chen, R.3
Zhao, J.G.4
Yu, P.5
-
28
-
-
84973472686
-
Diabetes Medications as Monotherapy or Metformin-Based Combination Therapy for Type 2 Diabetes: a Systematic Review and Meta-analysis
-
PID: 27088241
-
Maruthur NM, Tseng E, Hutfless S, Wilson LM, Suarez-Cuervo C, Berger Z, et al. Diabetes Medications as Monotherapy or Metformin-Based Combination Therapy for Type 2 Diabetes: a Systematic Review and Meta-analysis. Ann Intern Med. 2016;164(11):740–51.
-
(2016)
Ann Intern Med
, vol.164
, Issue.11
, pp. 740-751
-
-
Maruthur, N.M.1
Tseng, E.2
Hutfless, S.3
Wilson, L.M.4
Suarez-Cuervo, C.5
Berger, Z.6
-
29
-
-
84897447957
-
Canagliflozin: effects in overweight and obese subjects without diabetes mellitus
-
Bays HE, Weinstein R, Law G, Canovatchel W. Canagliflozin: effects in overweight and obese subjects without diabetes mellitus. Obesity (Silver Spring). 2014;22(4):1042–9.
-
(2014)
Obesity (Silver Spring).
, vol.22
, Issue.4
, pp. 1042-1049
-
-
Bays, H.E.1
Weinstein, R.2
Law, G.3
Canovatchel, W.4
-
30
-
-
84989327940
-
Dapagliflozin once-daily and exenatide once-weekly dual therapy: a 24-week randomized, placebo-controlled, phase II study examining effects on body weight and prediabetes in obese adults without diabetes
-
PID: 27550386
-
Lundkvist P, Sjostrom CD, Amini S, Pereira MJ, Johnsson E, Eriksson JW. Dapagliflozin once-daily and exenatide once-weekly dual therapy: a 24-week randomized, placebo-controlled, phase II study examining effects on body weight and prediabetes in obese adults without diabetes. Diabetes Obes Metab. 2017;19(1):49–60.
-
(2017)
Diabetes Obes Metab
, vol.19
, Issue.1
, pp. 49-60
-
-
Lundkvist, P.1
Sjostrom, C.D.2
Amini, S.3
Pereira, M.J.4
Johnsson, E.5
Eriksson, J.W.6
-
31
-
-
85020067582
-
Dapagliflozin once daily plus exenatide once weekly in obese adults without diabetes: sustained reductions in body weight, glycaemia and blood pressure over 1 year
-
PID: 28345814
-
Lundkvist P, Pereira MJ, Katsogiannos P, Sjostrom CD, Johnsson E, Eriksson JW. Dapagliflozin once daily plus exenatide once weekly in obese adults without diabetes: sustained reductions in body weight, glycaemia and blood pressure over 1 year. Diabetes Obes Metab. 2017;19(9):1276–88.
-
(2017)
Diabetes Obes Metab
, vol.19
, Issue.9
, pp. 1276-1288
-
-
Lundkvist, P.1
Pereira, M.J.2
Katsogiannos, P.3
Sjostrom, C.D.4
Johnsson, E.5
Eriksson, J.W.6
-
32
-
-
84898791935
-
Efficacy and safety of sodium glucose co-transport-2 inhibitors in type 2 diabetes: a meta-analysis of randomized clinical trials
-
PID: 24320621
-
Monami M, Nardini C, Mannucci E. Efficacy and safety of sodium glucose co-transport-2 inhibitors in type 2 diabetes: a meta-analysis of randomized clinical trials. Diabetes Obes Metab. 2014;16(5):457–66.
-
(2014)
Diabetes Obes Metab
, vol.16
, Issue.5
, pp. 457-466
-
-
Monami, M.1
Nardini, C.2
Mannucci, E.3
-
33
-
-
0034520399
-
Physiology of glucose homeostasis
-
PID: 11225963
-
Gerich JE. Physiology of glucose homeostasis. Diabetes Obes Metab. 2000;2(6):345–50.
-
(2000)
Diabetes Obes Metab
, vol.2
, Issue.6
, pp. 345-350
-
-
Gerich, J.E.1
-
34
-
-
84893827104
-
Dapagliflozin improves muscle insulin sensitivity but enhances endogenous glucose production
-
PID: 24463448
-
Merovci A, Solis-Herrera C, Daniele G, Eldor R, Fiorentino TV, Tripathy D, et al. Dapagliflozin improves muscle insulin sensitivity but enhances endogenous glucose production. J Clin Invest. 2014;124(2):509–14.
-
(2014)
J Clin Invest.
, vol.124
, Issue.2
, pp. 509-514
-
-
Merovci, A.1
Solis-Herrera, C.2
Daniele, G.3
Eldor, R.4
Fiorentino, T.V.5
Tripathy, D.6
-
35
-
-
84928628823
-
Comparative efficacy and safety of antidiabetic drug regimens added to metformin monotherapy in patients with type 2 diabetes: a network meta-analysis
-
PID: 25919293
-
Mearns ES, Sobieraj DM, White CM, Saulsberry WJ, Kohn CG, Doleh Y, et al. Comparative efficacy and safety of antidiabetic drug regimens added to metformin monotherapy in patients with type 2 diabetes: a network meta-analysis. PLoS ONE. 2015;10(4):e0125879.
-
(2015)
PLoS ONE
, vol.10
, Issue.4
-
-
Mearns, E.S.1
Sobieraj, D.M.2
White, C.M.3
Saulsberry, W.J.4
Kohn, C.G.5
Doleh, Y.6
-
36
-
-
85034752819
-
The Association Between the Dosage of SGLT2 Inhibitor and Weight Reduction in Type 2 Diabetes Patients: a Meta-Analysis
-
PID: 29165885
-
Cai X, Yang W, Gao X, Chen Y, Zhou L, Zhang S, et al. The Association Between the Dosage of SGLT2 Inhibitor and Weight Reduction in Type 2 Diabetes Patients: a Meta-Analysis. Obesity. 2018;26(1):70–80.
-
(2018)
Obesity.
, vol.26
, Issue.1
, pp. 70-80
-
-
Cai, X.1
Yang, W.2
Gao, X.3
Chen, Y.4
Zhou, L.5
Zhang, S.6
-
37
-
-
84892479365
-
Dapagliflozin maintains glycaemic control while reducing weight and body fat mass over 2 years in patients with type 2 diabetes mellitus inadequately controlled on metformin
-
PID: 23906445
-
Bolinder J, Ljunggren O, Johansson L, Wilding J, Langkilde AM, Sjostrom CD, et al. Dapagliflozin maintains glycaemic control while reducing weight and body fat mass over 2 years in patients with type 2 diabetes mellitus inadequately controlled on metformin. Diabetes Obes Metab. 2014;16(2):159–69.
-
(2014)
Diabetes Obes Metab
, vol.16
, Issue.2
, pp. 159-169
-
-
Bolinder, J.1
Ljunggren, O.2
Johansson, L.3
Wilding, J.4
Langkilde, A.M.5
Sjostrom, C.D.6
-
38
-
-
84924708763
-
Efficacy and safety of dapagliflozin monotherapy in people with Type 2 diabetes: a randomized double-blind placebo-controlled 102-week trial
-
PID: 25381876
-
Bailey CJ, Morales Villegas EC, Woo V, Tang W, Ptaszynska A, List JF. Efficacy and safety of dapagliflozin monotherapy in people with Type 2 diabetes: a randomized double-blind placebo-controlled 102-week trial. Diabet Med. 2015;32(4):531–41.
-
(2015)
Diabet Med
, vol.32
, Issue.4
, pp. 531-541
-
-
Bailey, C.J.1
Morales Villegas, E.C.2
Woo, V.3
Tang, W.4
Ptaszynska, A.5
List, J.F.6
-
39
-
-
84928426587
-
Long-term glycaemic response and tolerability of dapagliflozin versus a sulphonylurea as add-on therapy to metformin in patients with type 2 diabetes: 4-year data
-
PID: 25735400
-
Del Prato S, Nauck M, Duran-Garcia S, Maffei L, Rohwedder K, Theuerkauf A, et al. Long-term glycaemic response and tolerability of dapagliflozin versus a sulphonylurea as add-on therapy to metformin in patients with type 2 diabetes: 4-year data. Diabetes Obes Metab. 2015;17(6):581–90.
-
(2015)
Diabetes Obes Metab
, vol.17
, Issue.6
, pp. 581-590
-
-
Del Prato, S.1
Nauck, M.2
Duran-Garcia, S.3
Maffei, L.4
Rohwedder, K.5
Theuerkauf, A.6
-
40
-
-
84951906012
-
Energy Balance After Sodium-Glucose Cotransporter 2 Inhibition
-
PID: 26180105
-
Ferrannini G, Hach T, Crowe S, Sanghvi A, Hall KD, Ferrannini E. Energy Balance After Sodium-Glucose Cotransporter 2 Inhibition. Diabetes Care. 2015;38(9):1730–5.
-
(2015)
Diabetes Care
, vol.38
, Issue.9
, pp. 1730-1735
-
-
Ferrannini, G.1
Hach, T.2
Crowe, S.3
Sanghvi, A.4
Hall, K.D.5
Ferrannini, E.6
-
41
-
-
0028959193
-
Changes in energy expenditure resulting from altered body weight
-
PID: 7632212
-
Leibel RL, Rosenbaum M, Hirsch J. Changes in energy expenditure resulting from altered body weight. N Engl J Med. 1995;332(10):621–8.
-
(1995)
N Engl J Med
, vol.332
, Issue.10
, pp. 621-628
-
-
Leibel, R.L.1
Rosenbaum, M.2
Hirsch, J.3
-
42
-
-
85019391775
-
Coadministration of Canagliflozin and Phentermine for Weight Management in Overweight and Obese Individuals Without Diabetes: a Randomized Clinical Trial
-
PID: 28289041
-
Hollander P, Bays HE, Rosenstock J, Frustaci ME, Fung A, Vercruysse F, et al. Coadministration of Canagliflozin and Phentermine for Weight Management in Overweight and Obese Individuals Without Diabetes: a Randomized Clinical Trial. Diabetes Care. 2017;40(5):632–9.
-
(2017)
Diabetes Care
, vol.40
, Issue.5
, pp. 632-639
-
-
Hollander, P.1
Bays, H.E.2
Rosenstock, J.3
Frustaci, M.E.4
Fung, A.5
Vercruysse, F.6
-
43
-
-
84864371186
-
Weight loss induced by chronic dapagliflozin treatment is attenuated by compensatory hyperphagia in diet-induced obese (DIO) rats
-
PID: 22402735
-
Devenny JJ, Godonis HE, Harvey SJ, Rooney S, Cullen MJ, Pelleymounter MA. Weight loss induced by chronic dapagliflozin treatment is attenuated by compensatory hyperphagia in diet-induced obese (DIO) rats. Obesity. 2012;20(8):1645–52.
-
(2012)
Obesity.
, vol.20
, Issue.8
, pp. 1645-1652
-
-
Devenny, J.J.1
Godonis, H.E.2
Harvey, S.J.3
Rooney, S.4
Cullen, M.J.5
Pelleymounter, M.A.6
-
44
-
-
84893682957
-
SGLT2 selective inhibitor ipragliflozin reduces body fat mass by increasing fatty acid oxidation in high-fat diet-induced obese rats
-
PID: 24486393
-
Yokono M, Takasu T, Hayashizaki Y, Mitsuoka K, Kihara R, Muramatsu Y, et al. SGLT2 selective inhibitor ipragliflozin reduces body fat mass by increasing fatty acid oxidation in high-fat diet-induced obese rats. Eur J Pharmacol. 2014;727:66–74.
-
(2014)
Eur J Pharmacol
, vol.727
, pp. 66-74
-
-
Yokono, M.1
Takasu, T.2
Hayashizaki, Y.3
Mitsuoka, K.4
Kihara, R.5
Muramatsu, Y.6
-
45
-
-
84964608804
-
Shift to Fatty Substrate Utilization in Response to Sodium-Glucose Cotransporter 2 Inhibition in Subjects Without Diabetes and Patients With Type 2 Diabetes
-
PID: 26861783
-
Ferrannini E, Baldi S, Frascerra S, Astiarraga B, Heise T, Bizzotto R, et al. Shift to Fatty Substrate Utilization in Response to Sodium-Glucose Cotransporter 2 Inhibition in Subjects Without Diabetes and Patients With Type 2 Diabetes. Diabetes. 2016;65(5):1190–5.
-
(2016)
Diabetes
, vol.65
, Issue.5
, pp. 1190-1195
-
-
Ferrannini, E.1
Baldi, S.2
Frascerra, S.3
Astiarraga, B.4
Heise, T.5
Bizzotto, R.6
-
46
-
-
85020077721
-
SGLT2 Inhibition by Empagliflozin Promotes Fat Utilization and Browning and Attenuates Inflammation and Insulin Resistance by Polarizing M2 Macrophages in Diet-induced Obese Mice
-
PID: 28579299
-
Xu L, Nagata N, Nagashimada M, Zhuge F, Ni Y, Chen G, et al. SGLT2 Inhibition by Empagliflozin Promotes Fat Utilization and Browning and Attenuates Inflammation and Insulin Resistance by Polarizing M2 Macrophages in Diet-induced Obese Mice. EBioMedicine. 2017;20:137–49.
-
(2017)
EBioMedicine.
, vol.20
, pp. 137-149
-
-
Xu, L.1
Nagata, N.2
Nagashimada, M.3
Zhuge, F.4
Ni, Y.5
Chen, G.6
-
47
-
-
85041815856
-
Treatment of diabetic mice with the SGLT2 inhibitor TA-1887 antagonizes diabetic cachexia and decreases mortality
-
PID: 28900540
-
Sugizaki T, Zhu S, Guo G, Matsumoto A, Zhao J, Endo M, et al. Treatment of diabetic mice with the SGLT2 inhibitor TA-1887 antagonizes diabetic cachexia and decreases mortality. NPJ Aging Mech Dis. 2017;3:12.
-
(2017)
NPJ Aging Mech Dis.
, vol.3
, pp. 12
-
-
Sugizaki, T.1
Zhu, S.2
Guo, G.3
Matsumoto, A.4
Zhao, J.5
Endo, M.6
-
48
-
-
33644856005
-
Obesity and the role of adipose tissue in inflammation and metabolism
-
PID: 16470013
-
Greenberg AS, Obin MS. Obesity and the role of adipose tissue in inflammation and metabolism. Am J Clin Nutr. 2006;83(2):461S–5S.
-
(2006)
Am J Clin Nutr
, vol.83
, Issue.2
, pp. 461S-465S
-
-
Greenberg, A.S.1
Obin, M.S.2
-
49
-
-
85023777061
-
Canagliflozin and Cardiovascular and Renal Events in Type 2 Diabetes
-
PID: 28605608
-
Neal B, Perkovic V, Mahaffey KW, de Zeeuw D, Fulcher G, Erondu N, et al. Canagliflozin and Cardiovascular and Renal Events in Type 2 Diabetes. N Engl J Med. 2017;377(7):644–57.
-
(2017)
N Engl J Med
, vol.377
, Issue.7
, pp. 644-657
-
-
Neal, B.1
Perkovic, V.2
Mahaffey, K.W.3
de Zeeuw, D.4
Fulcher, G.5
Erondu, N.6
-
50
-
-
84944800184
-
Empagliflozin, Cardiovascular Outcomes, and Mortality in Type 2 Diabetes
-
PID: 26378978
-
Zinman B, Wanner C, Lachin JM, Fitchett D, Bluhmki E, Hantel S, et al. Empagliflozin, Cardiovascular Outcomes, and Mortality in Type 2 Diabetes. N Engl J Med. 2015;373(22):2117–28.
-
(2015)
N Engl J Med
, vol.373
, Issue.22
, pp. 2117-2128
-
-
Zinman, B.1
Wanner, C.2
Lachin, J.M.3
Fitchett, D.4
Bluhmki, E.5
Hantel, S.6
-
51
-
-
85060042753
-
Dapagliflozin and Cardiovascular Outcomes in Type 2 Diabetes
-
PID: 30415602
-
Wiviott SD, Raz I, Bonaca MP, Mosenzon O, Kato ET, Cahn A et al. Dapagliflozin and cardiovascular outcomes in type 2 diabetes. N Engl J Med. 2019;380(4):347–57.
-
(2019)
N Engl J Med
, vol.380
, Issue.4
, pp. 347-357
-
-
Wiviott, S.D.1
Raz, I.2
Bonaca, M.P.3
-
52
-
-
84964489933
-
Sodium-glucose cotransporter 2 inhibition and cardiovascular risk reduction in patients with type 2 diabetes: the emerging role of natriuresis
-
PID: 26880444
-
Rajasekeran H, Lytvyn Y, Cherney DZ. Sodium-glucose cotransporter 2 inhibition and cardiovascular risk reduction in patients with type 2 diabetes: the emerging role of natriuresis. Kidney Int. 2016;89(3):524–6.
-
(2016)
Kidney Int
, vol.89
, Issue.3
, pp. 524-526
-
-
Rajasekeran, H.1
Lytvyn, Y.2
Cherney, D.Z.3
-
53
-
-
84975840750
-
Can a Shift in Fuel Energetics Explain the Beneficial Cardiorenal Outcomes in the EMPA-REG OUTCOME Study?
-
PID: 27289124
-
Mudaliar S, Alloju S, Henry RR. Can a Shift in Fuel Energetics Explain the Beneficial Cardiorenal Outcomes in the EMPA-REG OUTCOME Study? A Unifying Hypothesis. Diabetes Care. 2016;39(7):1115–22.
-
(2016)
A Unifying Hypothesis. Diabetes Care.
, vol.39
, Issue.7
, pp. 1115-1122
-
-
Mudaliar, S.1
Alloju, S.2
Henry, R.R.3
-
54
-
-
85059501499
-
SGLT2 inhibitors for primary and secondary prevention of cardiovascular and renal outcomes in type 2 diabetes: a systematic review and meta-analysis of cardiovascular outcome trials
-
PID: 30424892
-
Zelniker TA, Wiviott SD, Raz I, Im K, Goodrich EL, Bonaca MP, et al. SGLT2 inhibitors for primary and secondary prevention of cardiovascular and renal outcomes in type 2 diabetes: a systematic review and meta-analysis of cardiovascular outcome trials. Lancet. 2019;393(10166):31–9.
-
(2019)
Lancet
, vol.393
, Issue.10166
, pp. 31-39
-
-
Zelniker, T.A.1
Wiviott, S.D.2
Raz, I.3
Im, K.4
Goodrich, E.L.5
Bonaca, M.P.6
-
55
-
-
0037048167
-
Overweight and obesity as determinants of cardiovascular risk: the Framingham experience
-
PID: 12196085
-
Wilson PW, D’Agostino RB, Sullivan L, Parise H, Kannel WB. Overweight and obesity as determinants of cardiovascular risk: the Framingham experience. Arch Intern Med. 2002;162(16):1867–72.
-
(2002)
Arch Intern Med
, vol.162
, Issue.16
, pp. 1867-1872
-
-
Wilson, P.W.1
D’Agostino, R.B.2
Sullivan, L.3
Parise, H.4
Kannel, W.B.5
-
56
-
-
84901198078
-
Blood pressure effects of sodium-glucose co-transport 2 (SGLT2) inhibitors
-
PID: 24631482
-
Oliva RV, Bakris GL. Blood pressure effects of sodium-glucose co-transport 2 (SGLT2) inhibitors. J Am Soc Hypertens. 2014;8(5):330–9.
-
(2014)
J Am Soc Hypertens.
, vol.8
, Issue.5
, pp. 330-339
-
-
Oliva, R.V.1
Bakris, G.L.2
-
57
-
-
84937817781
-
Dapagliflozin-induced weight loss affects 24-week glycated haemoglobin and blood pressure levels
-
PID: 25997813
-
Sjostrom CD, Hashemi M, Sugg J, Ptaszynska A, Johnsson E. Dapagliflozin-induced weight loss affects 24-week glycated haemoglobin and blood pressure levels. Diabetes Obes Metab. 2015;17(8):809–12.
-
(2015)
Diabetes Obes Metab
, vol.17
, Issue.8
, pp. 809-812
-
-
Sjostrom, C.D.1
Hashemi, M.2
Sugg, J.3
Ptaszynska, A.4
Johnsson, E.5
-
58
-
-
84880850027
-
Dapagliflozin a glucose-regulating drug with diuretic properties in subjects with type 2 diabetes
-
PID: 23668478
-
Lambers Heerspink HJ, de Zeeuw D, Wie L, Leslie B, List J. Dapagliflozin a glucose-regulating drug with diuretic properties in subjects with type 2 diabetes. Diabetes Obes Metab. 2013;15(9):853–62.
-
(2013)
Diabetes Obes Metab
, vol.15
, Issue.9
, pp. 853-862
-
-
Lambers Heerspink, H.J.1
de Zeeuw, D.2
Wie, L.3
Leslie, B.4
List, J.5
-
59
-
-
85044521391
-
A new class of drugs for heart failure: sGLT2 inhibitors reduce sympathetic overactivity
-
PID: 29415819
-
Sano M. A new class of drugs for heart failure: sGLT2 inhibitors reduce sympathetic overactivity. J Cardiol. 2018;71(5):471–6.
-
(2018)
J Cardiol
, vol.71
, Issue.5
, pp. 471-476
-
-
Sano, M.1
-
60
-
-
84930523330
-
Obesity-induced hypertension: interaction of neurohumoral and renal mechanisms
-
Hall JE, do Carmo JM, da Silva AA, Wang Z, Hall ME. Obesity-induced hypertension: interaction of neurohumoral and renal mechanisms. Circ Res. 2015;116(6):991-1006.
-
(2015)
Circ Res
, vol.116
, Issue.6
, pp. 991-1006
-
-
Hall, J.E.1
do Carmo, J.M.2
da Silva, A.A.3
Wang, Z.4
Hall, M.E.5
-
61
-
-
85042441341
-
For et al. SGLT2 inhibitors and renal outcomes in type 2 diabetes with or without renal impairment: A systematic review and meta-analysis
-
Seidu S, Kunutsor SK, Cos X, Gillani S, Khunti K, For et al. SGLT2 inhibitors and renal outcomes in type 2 diabetes with or without renal impairment: A systematic review and meta-analysis. Prim Care Diabetes. 2018;12(3):265-83.
-
(2018)
Prim Care Diabetes
, vol.12
, Issue.3
, pp. 265-283
-
-
Seidu, S.1
Kunutsor, S.K.2
Cos, X.3
Gillani, S.4
Khunti, K.5
-
62
-
-
85020459778
-
EMPA-REG OUTCOME: the Nephrologist’s Point of View
-
PID: 28606346
-
Wanner C. EMPA-REG OUTCOME: the Nephrologist’s Point of View. Am J Cardiol. 2017;120(1S):S59–67.
-
(2017)
Am J Cardiol
, vol.120
, Issue.1S
, pp. S59-S67
-
-
Wanner, C.1
-
63
-
-
85050481073
-
Efficacy and safety of dapagliflozin in patients with type 2 diabetes and moderate renal impairment (chronic kidney disease stage 3A): the DERIVE Study
-
PID: 29888547
-
Fioretto P, Del Prato S, Buse JB, Goldenberg R, Giorgino F, Reyner D, et al. Efficacy and safety of dapagliflozin in patients with type 2 diabetes and moderate renal impairment (chronic kidney disease stage 3A): the DERIVE Study. Diabetes Obes Metab. 2018;20(11):2532–40.
-
(2018)
Diabetes Obes Metab
, vol.20
, Issue.11
, pp. 2532-2540
-
-
Fioretto, P.1
Del Prato, S.2
Buse, J.B.3
Goldenberg, R.4
Giorgino, F.5
Reyner, D.6
-
64
-
-
84962362243
-
Efficacy and Safety of Canagliflozin, a Sodium-Glucose Cotransporter 2 Inhibitor, as Add-on to Insulin in Patients With Type 1 Diabetes
-
PID: 26486192
-
Henry RR, Thakkar P, Tong C, Polidori D, Alba M. Efficacy and Safety of Canagliflozin, a Sodium-Glucose Cotransporter 2 Inhibitor, as Add-on to Insulin in Patients With Type 1 Diabetes. Diabetes Care. 2015;38(12):2258–65.
-
(2015)
Diabetes Care
, vol.38
, Issue.12
, pp. 2258-2265
-
-
Henry, R.R.1
Thakkar, P.2
Tong, C.3
Polidori, D.4
Alba, M.5
-
65
-
-
85029446459
-
Efficacy and safety of dapagliflozin in patients with inadequately controlled type 1 diabetes (DEPICT-1): 24 week results from a multicentre, double-blind, phase 3, randomised controlled trial
-
Dandona P, Mathieu C, Phillip M, Hansen L, Griffen SC, Tschope D, et al. Efficacy and safety of dapagliflozin in patients with inadequately controlled type 1 diabetes (DEPICT-1): 24 week results from a multicentre, double-blind, phase 3, randomised controlled trial. The lancet Diabetes & endocrinology. 2017;5(11):864–76.
-
(2017)
The lancet Diabetes & endocrinology.
, vol.5
, Issue.11
, pp. 864-876
-
-
Dandona, P.1
Mathieu, C.2
Phillip, M.3
Hansen, L.4
Griffen, S.C.5
Tschope, D.6
-
66
-
-
85031780039
-
Effects of Sotagliflozin Added to Insulin in Patients with Type 1 Diabetes
-
PID: 28899222
-
Garg SK, Henry RR, Banks P, Buse JB, Davies MJ, Fulcher GR, et al. Effects of Sotagliflozin Added to Insulin in Patients with Type 1 Diabetes. N Engl J Med. 2017;377(24):2337–48.
-
(2017)
N Engl J Med
, vol.377
, Issue.24
, pp. 2337-2348
-
-
Garg, S.K.1
Henry, R.R.2
Banks, P.3
Buse, J.B.4
Davies, M.J.5
Fulcher, G.R.6
-
67
-
-
85105473327
-
Hypoglycemia in Patients with Diabetes and Renal Disease
-
PID: 26239457
-
Alsahli M, Gerich JE. Hypoglycemia in Patients with Diabetes and Renal Disease. J Clin Med. 2015;4(5):948–64.
-
(2015)
J Clin Med.
, vol.4
, Issue.5
, pp. 948-964
-
-
Alsahli, M.1
Gerich, J.E.2
-
68
-
-
84893872877
-
Metabolic response to sodium-glucose cotransporter 2 inhibition in type 2 diabetic patients
-
PID: 24463454
-
Ferrannini E, Muscelli E, Frascerra S, Baldi S, Mari A, Heise T, et al. Metabolic response to sodium-glucose cotransporter 2 inhibition in type 2 diabetic patients. J Clin Invest. 2014;124(2):499–508.
-
(2014)
J Clin Invest.
, vol.124
, Issue.2
, pp. 499-508
-
-
Ferrannini, E.1
Muscelli, E.2
Frascerra, S.3
Baldi, S.4
Mari, A.5
Heise, T.6
-
69
-
-
84962339296
-
Euglycemic Diabetic Ketoacidosis: a Potential Complication of Treatment With Sodium-Glucose Cotransporter 2 Inhibition
-
PID: 26078479
-
Peters AL, Buschur EO, Buse JB, Cohan P, Diner JC, Hirsch IB. Euglycemic Diabetic Ketoacidosis: a Potential Complication of Treatment With Sodium-Glucose Cotransporter 2 Inhibition. Diabetes Care. 2015;38(9):1687–93.
-
(2015)
Diabetes Care
, vol.38
, Issue.9
, pp. 1687-1693
-
-
Peters, A.L.1
Buschur, E.O.2
Buse, J.B.3
Cohan, P.4
Diner, J.C.5
Hirsch, I.B.6
-
70
-
-
85007514629
-
American Association of Clinical Endocrinologists and American College of Endocrinology Position Statement on the Association of Sglt-2 Inhibitors and Diabetic Ketoacidosis
-
PID: 27082665
-
Handelsman Y, Henry RR, Bloomgarden ZT, Dagogo-Jack S, DeFronzo RA, Einhorn D, et al. American Association of Clinical Endocrinologists and American College of Endocrinology Position Statement on the Association of Sglt-2 Inhibitors and Diabetic Ketoacidosis. Endocr Pract. 2016;22(6):753–62.
-
(2016)
Endocr Pract.
, vol.22
, Issue.6
, pp. 753-762
-
-
Handelsman, Y.1
Henry, R.R.2
Bloomgarden, Z.T.3
Dagogo-Jack, S.4
DeFronzo, R.A.5
Einhorn, D.6
-
71
-
-
85062116469
-
-
EASD 54th Annual Meeting 2018
-
Ryan P, J.B. B, Schuemie M, DeFalco F, Yuan Z, Stang P et al. Canagliflozin versus other antihyperglycaemic agents on the risk of below-knee amputation for patients with type 2 diabetes: a real world analysis of > 700,000 US patients. EASD 54th Annual Meeting 2018; http://abstractsonline.com/pp8/#!/4612/presentation/41802018.
-
Canagliflozin versus Other Antihyperglycaemic Agents on the Risk of Below-Knee Amputation for Patients with Type 2 Diabetes: A Real World Analysis of > 700,000 US Patients
-
-
Ryan, P.B.1
B Schuemie, M.2
Defalco, F.3
Yuan, Z.4
Stang, P.5
-
72
-
-
84907977576
-
A missing link in body weight homeostasis: the catabolic signal of the overfed state
-
PID: 25295786
-
Ravussin Y, Leibel RL, Ferrante AW Jr. A missing link in body weight homeostasis: the catabolic signal of the overfed state. Cell Metab. 2014;20(4):565–72.
-
(2014)
Cell Metab
, vol.20
, Issue.4
, pp. 565-572
-
-
Ravussin, Y.1
Leibel, R.L.2
Ferrante, A.W.3
-
73
-
-
85050729883
-
A Randomized Controlled Trial of Dapagliflozin Plus Once-Weekly Exenatide Versus Placebo in Individuals with Obesity and Without Diabetes: metabolic Effects and Markers Associated with Bodyweight Loss
-
PID: 29949016
-
Pereira MJ, Lundkvist P, Kamble PG, Lau J, Martins JG, Sjostrom CD, et al. A Randomized Controlled Trial of Dapagliflozin Plus Once-Weekly Exenatide Versus Placebo in Individuals with Obesity and Without Diabetes: metabolic Effects and Markers Associated with Bodyweight Loss. Diabetes Ther. 2018;9(4):1511–32.
-
(2018)
Diabetes Ther.
, vol.9
, Issue.4
, pp. 1511-1532
-
-
Pereira, M.J.1
Lundkvist, P.2
Kamble, P.G.3
Lau, J.4
Martins, J.G.5
Sjostrom, C.D.6
-
74
-
-
67349190497
-
A common genetic variant in WFS1 determines impaired glucagon-like peptide-1-induced insulin secretion
-
PID: 19330314
-
Schafer SA, Mussig K, Staiger H, Machicao F, Stefan N, Gallwitz B, et al. A common genetic variant in WFS1 determines impaired glucagon-like peptide-1-induced insulin secretion. Diabetologia. 2009;52(6):1075–82.
-
(2009)
Diabetologia
, vol.52
, Issue.6
, pp. 1075-1082
-
-
Schafer, S.A.1
Mussig, K.2
Staiger, H.3
Machicao, F.4
Stefan, N.5
Gallwitz, B.6
-
75
-
-
80051713342
-
Role of genetic variation in the human sodium-glucose cotransporter 2 gene (SGLT2) in glucose homeostasis
-
PID: 21830867
-
Enigk U, Breitfeld J, Schleinitz D, Dietrich K, Halbritter J, Fischer-Rosinsky A, et al. Role of genetic variation in the human sodium-glucose cotransporter 2 gene (SGLT2) in glucose homeostasis. Pharmacogenomics. 2011;12(8):1119–26.
-
(2011)
Pharmacogenomics.
, vol.12
, Issue.8
, pp. 1119-1126
-
-
Enigk, U.1
Breitfeld, J.2
Schleinitz, D.3
Dietrich, K.4
Halbritter, J.5
Fischer-Rosinsky, A.6
-
76
-
-
85010966919
-
Influence of common polymorphisms in the SLC5A2 gene on metabolic traits in subjects at increased risk of diabetes and on response to empagliflozin treatment in patients with diabetes
-
PID: 28134748
-
Zimdahl H, Haupt A, Brendel M, Bour L, Machicao F, Salsali A, et al. Influence of common polymorphisms in the SLC5A2 gene on metabolic traits in subjects at increased risk of diabetes and on response to empagliflozin treatment in patients with diabetes. Pharmacogenet Genomics. 2017;27(4):135–42.
-
(2017)
Pharmacogenet Genomics
, vol.27
, Issue.4
, pp. 135-142
-
-
Zimdahl, H.1
Haupt, A.2
Brendel, M.3
Bour, L.4
Machicao, F.5
Salsali, A.6
-
77
-
-
80052203917
-
Quantification of the effect of energy imbalance on bodyweight
-
PID: 21872751
-
Hall KD, Sacks G, Chandramohan D, Chow CC, Wang YC, Gortmaker SL, et al. Quantification of the effect of energy imbalance on bodyweight. Lancet. 2011;378(9793):826–37.
-
(2011)
Lancet
, vol.378
, Issue.9793
, pp. 826-837
-
-
Hall, K.D.1
Sacks, G.2
Chandramohan, D.3
Chow, C.C.4
Wang, Y.C.5
Gortmaker, S.L.6
-
78
-
-
85056797659
-
Efficacy and safety of LY3298176, a novel dual GIP and GLP-1 receptor agonist, in patients with type 2 diabetes: a randomised, placebo-controlled and active comparator-controlled phase 2 trial
-
Frias JP, Nauck MA, Van J, Kutner ME, Cui X, Benson C et al. Efficacy and safety of LY3298176, a novel dual GIP and GLP-1 receptor agonist, in patients with type 2 diabetes: a randomised, placebo-controlled and active comparator-controlled phase 2 trial. Lancet. 2018.
-
(2018)
Lancet
-
-
Frias, J.P.1
Nauck, M.A.2
Van, J.3
Kutner, M.E.4
Cui, X.5
Benson, C.6
-
79
-
-
85048885004
-
MEDI0382, a GLP-1 and glucagon receptor dual agonist, in obese or overweight patients with type 2 diabetes: a randomised, controlled, double-blind, ascending dose and phase 2a study
-
PID: 29945727
-
Ambery P, Parker VE, Stumvoll M, Posch MG, Heise T, Plum-Moerschel L, et al. MEDI0382, a GLP-1 and glucagon receptor dual agonist, in obese or overweight patients with type 2 diabetes: a randomised, controlled, double-blind, ascending dose and phase 2a study. Lancet. 2018;391(10140):2607–18.
-
(2018)
Lancet
, vol.391
, Issue.10140
, pp. 2607-2618
-
-
Ambery, P.1
Parker, V.E.2
Stumvoll, M.3
Posch, M.G.4
Heise, T.5
Plum-Moerschel, L.6
-
80
-
-
84912049381
-
Lorcaserin, phentermine topiramate combination, and naltrexone bupropion combination for weight loss: the 15-min challenge to sort these agents out
-
PID: 25418525
-
Citrome L. Lorcaserin, phentermine topiramate combination, and naltrexone bupropion combination for weight loss: the 15-min challenge to sort these agents out. Int J Clin Pract. 2014;68(12):1401–5.
-
(2014)
Int J Clin Pract
, vol.68
, Issue.12
, pp. 1401-1405
-
-
Citrome, L.1
-
81
-
-
84989180878
-
Combination therapy with GLP-1 analogues and SGLT-2 inhibitors in the management of diabesity: the real world experience
-
PID: 27696231
-
Deol H, Lekkakou L, Viswanath AK, Pappachan JM. Combination therapy with GLP-1 analogues and SGLT-2 inhibitors in the management of diabesity: the real world experience. Endocrine. 2017;55(1):173–8.
-
(2017)
Endocrine
, vol.55
, Issue.1
, pp. 173-178
-
-
Deol, H.1
Lekkakou, L.2
Viswanath, A.K.3
Pappachan, J.M.4
-
82
-
-
84901463555
-
Exploring glycosuria as a mechanism for weight and fat mass reduction. A pilot study with remogliflozin etabonate and sergliflozin etabonate in healthy obese subjects
-
Napolitano A, Miller S, Murgatroyd PR, Hussey E, Dobbins RL, Bullmore ET et al. Exploring glycosuria as a mechanism for weight and fat mass reduction. A pilot study with remogliflozin etabonate and sergliflozin etabonate in healthy obese subjects. J Clin Transl Endocrinol. 2014;1(1):e3-e8.
-
(2014)
J Clin Transl Endocrinol
, vol.1
, Issue.1
, pp. e3-e8
-
-
Napolitano, A.1
Miller, S.2
Murgatroyd, P.R.3
Hussey, E.4
Dobbins, R.L.5
Bullmore, E.T.6
-
83
-
-
85017253336
-
Dapagliflozin once-daily and exenatide once-weekly dual therapy: A 24-week randomized, placebo-controlled, phase II study examining effects on body weight and prediabetes in obese adults without diabetes
-
Lundkvist P, Sjostrom CD, Amini S, Pereira MJ, Johnsson E, Eriksson JW. Dapagliflozin once-daily and exenatide once-weekly dual therapy: A 24-week randomized, placebo-controlled, phase II study examining effects on body weight and prediabetes in obese adults without diabetes. Diabetes Obes Metab. 2016.
-
(2016)
Diabetes Obes Metab
-
-
Lundkvist, P.1
Sjostrom, C.D.2
Amini, S.3
Pereira, M.J.4
Johnsson, E.5
Eriksson, J.W.6
-
84
-
-
84866003015
-
Dapagliflozin monotherapy in drug-naive patients with diabetes: a randomized-controlled trial of low-dose range
-
PID: 22776824
-
Bailey CJ, Iqbal N, T’Joen C, List JF. Dapagliflozin monotherapy in drug-naive patients with diabetes: a randomized-controlled trial of low-dose range. Diabetes Obes Metab. 2012;14(10):951–9.
-
(2012)
Diabetes Obes Metab
, vol.14
, Issue.10
, pp. 951-959
-
-
Bailey, C.J.1
Iqbal, N.2
T’Joen, C.3
List, J.F.4
-
85
-
-
77956921439
-
Dapagliflozin monotherapy in type 2 diabetic patients with inadequate glycemic control by diet and exercise: a randomized, double-blind, placebo-controlled, phase 3 trial
-
PID: 20566676
-
Ferrannini E, Ramos SJ, Salsali A, Tang W, List JF. Dapagliflozin monotherapy in type 2 diabetic patients with inadequate glycemic control by diet and exercise: a randomized, double-blind, placebo-controlled, phase 3 trial. Diabetes Care. 2010;33(10):2217–24.
-
(2010)
Diabetes Care
, vol.33
, Issue.10
, pp. 2217-2224
-
-
Ferrannini, E.1
Ramos, S.J.2
Salsali, A.3
Tang, W.4
List, J.F.5
-
86
-
-
84892368256
-
Dapagliflozin as monotherapy in drug-naive Asian patients with type 2 diabetes mellitus: A randomized, blinded, prospective phase III study
-
Ji L, Ma J, Li H, Mansfield TA, T’Joen C L, Iqbal N et al. Dapagliflozin as monotherapy in drug-naive Asian patients with type 2 diabetes mellitus: a randomized, blinded, prospective phase III study. Clin Ther. 2014;36(1):84-100 e9.
-
(2014)
Clin Ther
, vol.36
, Issue.1
, pp. 84-100
-
-
Ji, L.1
Ma, J.2
Li, H.3
Mansfield, T.A.4
T’Joen, C.L.5
Iqbal, N.6
-
87
-
-
84914181817
-
Efficacy and safety of dapagliflozin monotherapy in Japanese patients with type 2 diabetes inadequately controlled by diet and exercise
-
PID: 24909293
-
Kaku K, Kiyosue A, Inoue S, Ueda N, Tokudome T, Yang J, et al. Efficacy and safety of dapagliflozin monotherapy in Japanese patients with type 2 diabetes inadequately controlled by diet and exercise. Diabetes Obes Metab. 2014;16(11):1102–10.
-
(2014)
Diabetes Obes Metab
, vol.16
, Issue.11
, pp. 1102-1110
-
-
Kaku, K.1
Kiyosue, A.2
Inoue, S.3
Ueda, N.4
Tokudome, T.5
Yang, J.6
-
88
-
-
77953857048
-
Effect of dapagliflozin in patients with type 2 diabetes who have inadequate glycaemic control with metformin: a randomised, double-blind, placebo-controlled trial
-
PID: 20609968
-
Bailey CJ, Gross JL, Pieters A, Bastien A, List JF. Effect of dapagliflozin in patients with type 2 diabetes who have inadequate glycaemic control with metformin: a randomised, double-blind, placebo-controlled trial. Lancet. 2010;375(9733):2223–33.
-
(2010)
Lancet
, vol.375
, Issue.9733
, pp. 2223-2233
-
-
Bailey, C.J.1
Gross, J.L.2
Pieters, A.3
Bastien, A.4
List, J.F.5
-
89
-
-
84873960885
-
Dapagliflozin add-on to metformin in type 2 diabetes inadequately controlled with metformin: a randomized, double-blind, placebo-controlled 102-week trial
-
PID: 23425012
-
Bailey CJ, Gross JL, Hennicken D, Iqbal N, Mansfield TA, List JF. Dapagliflozin add-on to metformin in type 2 diabetes inadequately controlled with metformin: a randomized, double-blind, placebo-controlled 102-week trial. BMC Med. 2013;11:43.
-
(2013)
BMC Med.
, vol.11
, pp. 43
-
-
Bailey, C.J.1
Gross, J.L.2
Hennicken, D.3
Iqbal, N.4
Mansfield, T.A.5
List, J.F.6
-
90
-
-
84858020943
-
Effects of dapagliflozin on body weight, total fat mass, and regional adipose tissue distribution in patients with type 2 diabetes mellitus with inadequate glycemic control on metformin
-
PID: 22238392
-
Bolinder J, Ljunggren O, Kullberg J, Johansson L, Wilding J, Langkilde AM, et al. Effects of dapagliflozin on body weight, total fat mass, and regional adipose tissue distribution in patients with type 2 diabetes mellitus with inadequate glycemic control on metformin. J Clin Endocrinol Metab. 2012;97(3):1020–31.
-
(2012)
J Clin Endocrinol Metab
, vol.97
, Issue.3
, pp. 1020-1031
-
-
Bolinder, J.1
Ljunggren, O.2
Kullberg, J.3
Johansson, L.4
Wilding, J.5
Langkilde, A.M.6
-
91
-
-
80052524011
-
Effect of dapagliflozin in patients with type 2 diabetes who have inadequate glycaemic control with glimepiride: a randomized, 24-week, double-blind, placebo-controlled trial
-
PID: 21672123
-
Strojek K, Yoon KH, Hruba V, Elze M, Langkilde AM, Parikh S. Effect of dapagliflozin in patients with type 2 diabetes who have inadequate glycaemic control with glimepiride: a randomized, 24-week, double-blind, placebo-controlled trial. Diabetes Obes Metab. 2011;13(10):928–38.
-
(2011)
Diabetes Obes Metab
, vol.13
, Issue.10
, pp. 928-938
-
-
Strojek, K.1
Yoon, K.H.2
Hruba, V.3
Elze, M.4
Langkilde, A.M.5
Parikh, S.6
-
92
-
-
84915809485
-
Dapagliflozin added to glimepiride in patients with type 2 diabetes mellitus sustains glycemic control and weight loss over 48 weeks: a randomized, double-blind, parallel-group, placebo-controlled trial
-
PID: 24920277
-
Strojek K, Yoon KH, Hruba V, Sugg J, Langkilde AM, Parikh S. Dapagliflozin added to glimepiride in patients with type 2 diabetes mellitus sustains glycemic control and weight loss over 48 weeks: a randomized, double-blind, parallel-group, placebo-controlled trial. Diabetes Ther. 2014;5(1):267–83.
-
(2014)
Diabetes Ther.
, vol.5
, Issue.1
, pp. 267-283
-
-
Strojek, K.1
Yoon, K.H.2
Hruba, V.3
Sugg, J.4
Langkilde, A.M.5
Parikh, S.6
-
93
-
-
80155124676
-
Dapagliflozin versus glipizide as add-on therapy in patients with type 2 diabetes who have inadequate glycemic control with metformin: a randomized, 52-week, double-blind, active-controlled noninferiority trial
-
PID: 21816980
-
Nauck MA, Del Prato S, Meier JJ, Duran-Garcia S, Rohwedder K, Elze M, et al. Dapagliflozin versus glipizide as add-on therapy in patients with type 2 diabetes who have inadequate glycemic control with metformin: a randomized, 52-week, double-blind, active-controlled noninferiority trial. Diabetes Care. 2011;34(9):2015–22.
-
(2011)
Diabetes Care
, vol.34
, Issue.9
, pp. 2015-2022
-
-
Nauck, M.A.1
Del Prato, S.2
Meier, J.J.3
Duran-Garcia, S.4
Rohwedder, K.5
Elze, M.6
-
94
-
-
84914144323
-
Durability of glycaemic efficacy over 2 years with dapagliflozin versus glipizide as add-on therapies in patients whose type 2 diabetes mellitus is inadequately controlled with metformin
-
PID: 24919526
-
Nauck MA, Del Prato S, Duran-Garcia S, Rohwedder K, Langkilde AM, Sugg J, et al. Durability of glycaemic efficacy over 2 years with dapagliflozin versus glipizide as add-on therapies in patients whose type 2 diabetes mellitus is inadequately controlled with metformin. Diabetes Obes Metab. 2014;16(11):1111–20.
-
(2014)
Diabetes Obes Metab
, vol.16
, Issue.11
, pp. 1111-1120
-
-
Nauck, M.A.1
Del Prato, S.2
Duran-Garcia, S.3
Rohwedder, K.4
Langkilde, A.M.5
Sugg, J.6
-
95
-
-
84955184453
-
Efficacy and safety of canagliflozin when used in conjunction with incretin-mimetic therapy in patients with type 2 diabetes
-
PID: 26450639
-
Fulcher G, Matthews DR, Perkovic V, de Zeeuw D, Mahaffey KW, Mathieu C, et al. Efficacy and safety of canagliflozin when used in conjunction with incretin-mimetic therapy in patients with type 2 diabetes. Diabetes Obes Metab. 2016;18(1):82–91.
-
(2016)
Diabetes Obes Metab
, vol.18
, Issue.1
, pp. 82-91
-
-
Fulcher, G.1
Matthews, D.R.2
Perkovic, V.3
de Zeeuw, D.4
Mahaffey, K.W.5
Mathieu, C.6
-
96
-
-
85042458412
-
Dulaglutide as add-on therapy to SGLT2 inhibitors in patients with inadequately controlled type 2 diabetes (AWARD-10): a 24-week, randomised, double-blind, placebo-controlled trial
-
Ludvik B, Frias JP, Tinahones FJ, Wainstein J, Jiang H, Robertson KE, et al. Dulaglutide as add-on therapy to SGLT2 inhibitors in patients with inadequately controlled type 2 diabetes (AWARD-10): a 24-week, randomised, double-blind, placebo-controlled trial. The lancet Diabetes & endocrinology. 2018;6(5):370–81.
-
(2018)
The lancet Diabetes & endocrinology.
, vol.6
, Issue.5
, pp. 370-381
-
-
Ludvik, B.1
Frias, J.P.2
Tinahones, F.J.3
Wainstein, J.4
Jiang, H.5
Robertson, K.E.6
-
97
-
-
84896701131
-
Dapagliflozin is effective as add-on therapy to sitagliptin with or without metformin: a 24-week, multicenter, randomized, double-blind, placebo-controlled study
-
Jabbour SA, Hardy E, Sugg J, Parikh S, Study G. Dapagliflozin is effective as add-on therapy to sitagliptin with or without metformin: a 24-week, multicenter, randomized, double-blind, placebo-controlled study. Diabetes Care. 2014;37(3):740–50.
-
(2014)
Diabetes Care
, vol.37
, Issue.3
, pp. 740-750
-
-
-
98
-
-
84928176749
-
Combination of empagliflozin and linagliptin as second-line therapy in subjects with type 2 diabetes inadequately controlled on metformin
-
PID: 25583754
-
DeFronzo RA, Lewin A, Patel S, Liu D, Kaste R, Woerle HJ, et al. Combination of empagliflozin and linagliptin as second-line therapy in subjects with type 2 diabetes inadequately controlled on metformin. Diabetes Care. 2015;38(3):384–93.
-
(2015)
Diabetes Care
, vol.38
, Issue.3
, pp. 384-393
-
-
DeFronzo, R.A.1
Lewin, A.2
Patel, S.3
Liu, D.4
Kaste, R.5
Woerle, H.J.6
-
99
-
-
85044247632
-
Ertugliflozin plus sitagliptin versus either individual agent over 52 weeks in patients with type 2 diabetes mellitus inadequately controlled with metformin: the VERTIS FACTORIAL randomized trial
-
PID: 29266675
-
Pratley RE, Eldor R, Raji A, Golm G, Huyck SB, Qiu Y, et al. Ertugliflozin plus sitagliptin versus either individual agent over 52 weeks in patients with type 2 diabetes mellitus inadequately controlled with metformin: the VERTIS FACTORIAL randomized trial. Diabetes Obes Metab. 2018;20(5):1111–20.
-
(2018)
Diabetes Obes Metab
, vol.20
, Issue.5
, pp. 1111-1120
-
-
Pratley, R.E.1
Eldor, R.2
Raji, A.3
Golm, G.4
Huyck, S.B.5
Qiu, Y.6
-
100
-
-
84928201032
-
Dual add-on therapy in type 2 diabetes poorly controlled with metformin monotherapy: a randomized double-blind trial of saxagliptin plus dapagliflozin addition versus single addition of saxagliptin or dapagliflozin to metformin
-
PID: 25352655
-
Rosenstock J, Hansen L, Zee P, Li Y, Cook W, Hirshberg B, et al. Dual add-on therapy in type 2 diabetes poorly controlled with metformin monotherapy: a randomized double-blind trial of saxagliptin plus dapagliflozin addition versus single addition of saxagliptin or dapagliflozin to metformin. Diabetes Care. 2015;38(3):376–83.
-
(2015)
Diabetes Care
, vol.38
, Issue.3
, pp. 376-383
-
-
Rosenstock, J.1
Hansen, L.2
Zee, P.3
Li, Y.4
Cook, W.5
Hirshberg, B.6
-
101
-
-
84990243738
-
Efficacy and safety of triple therapy with dapagliflozin add-on to saxagliptin plus metformin over 52 weeks in patients with type 2 diabetes
-
PID: 27385192
-
Mathieu C, Herrera Marmolejo M, Gonzalez Gonzalez JG, Hansen L, Chen H, Johnsson E, et al. Efficacy and safety of triple therapy with dapagliflozin add-on to saxagliptin plus metformin over 52 weeks in patients with type 2 diabetes. Diabetes Obes Metab. 2016;18(11):1134–7.
-
(2016)
Diabetes Obes Metab
, vol.18
, Issue.11
, pp. 1134-1137
-
-
Mathieu, C.1
Herrera Marmolejo, M.2
Gonzalez Gonzalez, J.G.3
Hansen, L.4
Chen, H.5
Johnsson, E.6
-
102
-
-
84862875221
-
Effects of dapagliflozin, an SGLT2 inhibitor, on HbA(1c), body weight, and hypoglycemia risk in patients with type 2 diabetes inadequately controlled on pioglitazone monotherapy
-
PID: 22446170
-
Rosenstock J, Vico M, Wei L, Salsali A, List JF. Effects of dapagliflozin, an SGLT2 inhibitor, on HbA(1c), body weight, and hypoglycemia risk in patients with type 2 diabetes inadequately controlled on pioglitazone monotherapy. Diabetes Care. 2012;35(7):1473–8.
-
(2012)
Diabetes Care
, vol.35
, Issue.7
, pp. 1473-1478
-
-
Rosenstock, J.1
Vico, M.2
Wei, L.3
Salsali, A.4
List, J.F.5
-
103
-
-
84892477577
-
Empagliflozin improves glycaemic and weight control as add-on therapy to pioglitazone or pioglitazone plus metformin in patients with type 2 diabetes: a 24-week, randomized, placebo-controlled trial
-
PID: 23906415
-
Kovacs CS, Seshiah V, Swallow R, Jones R, Rattunde H, Woerle HJ, et al. Empagliflozin improves glycaemic and weight control as add-on therapy to pioglitazone or pioglitazone plus metformin in patients with type 2 diabetes: a 24-week, randomized, placebo-controlled trial. Diabetes Obes Metab. 2014;16(2):147–58.
-
(2014)
Diabetes Obes Metab
, vol.16
, Issue.2
, pp. 147-158
-
-
Kovacs, C.S.1
Seshiah, V.2
Swallow, R.3
Jones, R.4
Rattunde, H.5
Woerle, H.J.6
-
104
-
-
84892488179
-
Dapagliflozin in patients with type 2 diabetes receiving high doses of insulin: Efficacy and safety over 2 years
-
Wilding JP, Woo V, Rohwedder K, Sugg J, Parikh S, Dapagliflozin 006 Study G. Dapagliflozin in patients with type 2 diabetes receiving high doses of insulin: efficacy and safety over 2 years. Diabetes Obes Metab. 2014;16(2):124-36.
-
(2014)
Diabetes Obes Metab
, vol.16
, Issue.2
, pp. 124-136
-
-
Wilding, J.P.1
Woo, V.2
Rohwedder, K.3
Sugg, J.4
Parikh, S.5
-
105
-
-
84903511385
-
Improved glucose control with weight loss, lower insulin doses, and no increased hypoglycemia with empagliflozin added to titrated multiple daily injections of insulin in obese inadequately controlled type 2 diabetes
-
PID: 24929430
-
Rosenstock J, Jelaska A, Frappin G, Salsali A, Kim G, Woerle HJ, et al. Improved glucose control with weight loss, lower insulin doses, and no increased hypoglycemia with empagliflozin added to titrated multiple daily injections of insulin in obese inadequately controlled type 2 diabetes. Diabetes Care. 2014;37(7):1815–23.
-
(2014)
Diabetes Care
, vol.37
, Issue.7
, pp. 1815-1823
-
-
Rosenstock, J.1
Jelaska, A.2
Frappin, G.3
Salsali, A.4
Kim, G.5
Woerle, H.J.6
|