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Volumn 159, Issue 4, 2013, Pages 262-274

Sodium-glucose cotransporter 2 inhibitors for type 2 diabetes: A systematic review and meta-analysis

Author keywords

[No Author keywords available]

Indexed keywords

ANTIDIABETIC AGENT; CANAGLIFLOZIN; DAPAGLIFLOZIN; EMPAGLIFLOZIN; ERTUGLIFLOZIN; HEMOGLOBIN A1C; INSULIN; IPRAGLIFLOZIN; LUSEOGLIFLOZIN; METFORMIN; PLACEBO; REMOGLIFLOZIN ETABONATE; SITAGLIPTIN; SODIUM GLUCOSE COTRANSPORTER 2; SODIUM GLUCOSE COTRANSPORTER 2 INHIBITOR; SULFONYLUREA; TOFOGLIFLOZIN; UNCLASSIFIED DRUG;

EID: 84882251091     PISSN: 00034819     EISSN: 15393704     Source Type: Journal    
DOI: 10.7326/0003-4819-159-4-201308200-00007     Document Type: Review
Times cited : (784)

References (79)
  • 1
    • 84864283226 scopus 로고    scopus 로고
    • SGLT2 inhibition in diabetes mellitus: Rationale and clinical prospects
    • [PMID: 22310849]
    • Ferrannini E, Solini A. SGLT2 inhibition in diabetes mellitus: rationale and clinical prospects. Nat Rev Endocrinol. 2012;8:495-502. [PMID: 22310849]
    • (2012) Nat Rev Endocrinol , vol.8 , pp. 495-502
    • Ferrannini, E.1    Solini, A.2
  • 2
    • 33644688031 scopus 로고    scopus 로고
    • Glucose transporters in human renal proximal tubular cells isolated from the urine of patients with non-insulin-dependent diabetes
    • [PMID: 16306358]
    • Rahmoune H, Thompson PW, Ward JM, Smith CD, Hong G, Brown J. Glucose transporters in human renal proximal tubular cells isolated from the urine of patients with non-insulin-dependent diabetes. Diabetes. 2005;54:3427-34. [PMID: 16306358]
    • (2005) Diabetes , vol.54 , pp. 3427-3434
    • Rahmoune, H.1    Thompson, P.W.2    Ward, J.M.3    Smith, C.D.4    Hong, G.5    Brown, J.6
  • 3
    • 84866268783 scopus 로고    scopus 로고
    • American Diabetes Association (ADA). Management of hyperglycemia in type 2 diabetes: A patient-centered approach: Position statement of the American Diabetes Association (ADA) and the European Association for the Study of Diabetes (EASD)
    • [PMID: 22517736]
    • Inzucchi SE, Bergenstal RM, Buse JB, Diamant M, Ferrannini E, Nauck M, et al; American Diabetes Association (ADA). Management of hyperglycemia in type 2 diabetes: a patient-centered approach: position statement of the American Diabetes Association (ADA) and the European Association for the Study of Diabetes (EASD). Diabetes Care. 2012;35:1364-79. [PMID: 22517736]
    • (2012) Diabetes Care , vol.35 , pp. 1364-1379
    • Inzucchi, S.E.1    Bergenstal, R.M.2    Buse, J.B.3    Diamant, M.4    Ferrannini, E.5    Nauck, M.6
  • 4
    • 84882288019 scopus 로고    scopus 로고
    • U.S. Food and Drug Administration. FDA Briefing Document. NDA 202293. Dapagliflozin Tablets, 5 and 10 mg. Rockville, MD: U.S. Food and Drug Administration;, Accessed at, on 1 April 2013
    • U.S. Food and Drug Administration. FDA Briefing Document. NDA 202293. Dapagliflozin Tablets, 5 and 10 mg. Rockville, MD: U.S. Food and Drug Administration; 2011. Accessed at www.fda.gov/downloads/AdvisoryCommittees/CommitteesMeetingMaterials/drugs/EndocrinologicandMetabolic DrugsAdvisoryCommittee/ucm262994.pdf on 1 April 2013.
    • (2011)
  • 5
    • 84856881292 scopus 로고    scopus 로고
    • FDA rejects novel diabetes drug over safety fears
    • [PMID: 22334883]
    • Burki TK. FDA rejects novel diabetes drug over safety fears. Lancet. 2012; 379:507. [PMID: 22334883]
    • (2012) Lancet , vol.379 , pp. 507
    • Burki, T.K.1
  • 6
    • 84882254973 scopus 로고    scopus 로고
    • European Medicines Agency. Assessment Report: Forxiga (Dapagliflozin). Procedure no. EMEA/H/C/002322. London: European Medicines Agency, Accessed at, on 1 April 2013
    • European Medicines Agency. Assessment Report: Forxiga (Dapagliflozin). Procedure no. EMEA/H/C/002322. London: European Medicines Agency; 2012. Accessed at www.ema.europa.eu/docs/en_GB/document_library/EPAR _-_Public_assessment_report/human/002322/WC500136024.pdf on 1 April 2013.
  • 7
    • 84882268701 scopus 로고    scopus 로고
    • U.S. Food and Drug Administration. FDA Briefing Document. NDA 204042. Invokana (Canagliflozin) Tablets. Rockville, MD: U.S. Food and Drug Administration; 2013. Accessed at, on 24 January 2013
    • U.S. Food and Drug Administration. FDA Briefing Document. NDA 204042. Invokana (Canagliflozin) Tablets. Rockville, MD: U.S. Food and Drug Administration; 2013. Accessed at www.fda.gov/downloads/AdvisoryCommittees/CommitteesMeetingMaterials/Drugs/EndocrinologicandMetabolicDrugs AdvisoryCommittee/UCM334550.pdf on 24 January 2013.
  • 8
    • 84882237066 scopus 로고    scopus 로고
    • U.S. Food and Drug Administration. FDA approves Invokana to treat type 2 diabetes [news release]. Rockville, MD: U.S. Food and Drug Administration; 29 March 2013. Accessed at, on 1 April 2013
    • U.S. Food and Drug Administration. FDA approves Invokana to treat type 2 diabetes [news release]. Rockville, MD: U.S. Food and Drug Administration; 29 March 2013. Accessed at www.fda.gov/NewsEvents/Newsroom/PressAnnouncements/ucm345848.htm on 1 April 2013.
  • 9
    • 84869745717 scopus 로고    scopus 로고
    • Systematic review of SGLT2 receptor inhibitors in dual or triple therapy in type 2 diabetes
    • [PMID: 23087012]
    • Clar C, Gill JA, Court R, Waugh N. Systematic review of SGLT2 receptor inhibitors in dual or triple therapy in type 2 diabetes. BMJ Open. 2012;2. [PMID: 23087012]
    • (2012) BMJ Open , pp. 2
    • Clar, C.1    Gill, J.A.2    Court, R.3    Waugh, N.4
  • 10
    • 84860183617 scopus 로고    scopus 로고
    • A novel approach to control hyperglycemia in type 2 diabetes: Sodium glucose co-transport (SGLT) inhibitors: Systematic review and meta-analysis of randomized trials
    • [PMID: 21495788]
    • Musso G, Gambino R, Cassader M, Pagano G. A novel approach to control hyperglycemia in type 2 diabetes: sodium glucose co-transport (SGLT) inhibitors: systematic review and meta-analysis of randomized trials. Ann Med. 2012;44: 375-93. [PMID: 21495788]
    • (2012) Ann Med , vol.44 , pp. 375-393
    • Musso, G.1    Gambino, R.2    Cassader, M.3    Pagano, G.4
  • 11
    • 69149107727 scopus 로고    scopus 로고
    • The PRISMA statement for reporting systematic reviews and meta-analyses of studies that evaluate health care interventions: Explanation and elaboration
    • [PMID: 19622512]
    • Liberati A, Altman DG, Tetzlaff J, Mulrow C, Gøtzsche PC, Ioannidis JP, et al. The PRISMA statement for reporting systematic reviews and meta-analyses of studies that evaluate health care interventions: explanation and elaboration. Ann Intern Med. 2009;151:W65-94. [PMID: 19622512]
    • (2009) Ann Intern Med , vol.151
    • Liberati, A.1    Altman, D.G.2    Tetzlaff, J.3    Mulrow, C.4    Gøtzsche, P.C.5    Ioannidis, J.P.6
  • 12
    • 84882282917 scopus 로고    scopus 로고
    • Scottish Intercollegiate Guidelines Network. Search Filters. Edinburgh, United Kingdom: Scottish Intercollegiate Guidelines Network; 2013. Accessed at, on 8 January
    • Scottish Intercollegiate Guidelines Network. Search Filters. Edinburgh, United Kingdom: Scottish Intercollegiate Guidelines Network; 2013. Accessed at www.sign.ac.uk/methodology/filters.html on 8 January 2013.
    • (2013)
  • 14
    • 84859001212 scopus 로고    scopus 로고
    • Cochrane Bias Methods Group. The Cochrane Collaboration's tool for assessing risk of bias in randomised trials
    • [PMID: 22008217]
    • Higgins JP, Altman DG, Gøtzsche PC, Jüni P, Moher D, Oxman AD, et al; Cochrane Bias Methods Group. The Cochrane Collaboration's tool for assessing risk of bias in randomised trials. BMJ. 2011;343:d5928. [PMID: 22008217]
    • (2011) BMJ , vol.343
    • Higgins, J.P.1    Altman, D.G.2    Gøtzsche, P.C.3    Jüni, P.4    Moher, D.5    Oxman, A.D.6
  • 15
    • 0030922816 scopus 로고    scopus 로고
    • Bias in meta-analysis detected by a simple, graphical test
    • [PMID: 9310563]
    • Egger M, Davey Smith G, Schneider M, Minder C. Bias in meta-analysis detected by a simple, graphical test. BMJ. 1997;315:629-34. [PMID: 9310563]
    • (1997) BMJ , vol.315 , pp. 629-634
    • Egger, M.1    Davey Smith, G.2    Schneider, M.3    Minder, C.4
  • 16
    • 79951952372 scopus 로고    scopus 로고
    • GRADE guidelines: 1. Introduction-GRADE evidence profiles and summary of findings tables
    • [PMID: 21195583]
    • Guyatt G, Oxman AD, Akl EA, Kunz R, Vist G, Brozek J, et al. GRADE guidelines: 1. Introduction-GRADE evidence profiles and summary of findings tables. J Clin Epidemiol. 2011;64:383-94. [PMID: 21195583]
    • (2011) J Clin Epidemiol , vol.64 , pp. 383-394
    • Guyatt, G.1    Oxman, A.D.2    Akl, E.A.3    Kunz, R.4    Vist, G.5    Brozek, J.6
  • 17
    • 80054981259 scopus 로고    scopus 로고
    • GRADE Working Group. GRADE guidelines: 7. Rating the quality of evidence-inconsistency
    • [PMID: 21803546]
    • Guyatt GH, Oxman AD, Kunz R, Woodcock J, Brozek J, Helfand M, et al; GRADE Working Group. GRADE guidelines: 7. Rating the quality of evidence-inconsistency. J Clin Epidemiol. 2011;64:1294-302. [PMID: 21803546]
    • (2011) J Clin Epidemiol , vol.64 , pp. 1294-1302
    • Guyatt, G.H.1    Oxman, A.D.2    Kunz, R.3    Woodcock, J.4    Brozek, J.5    Helfand, M.6
  • 18
    • 35848930559 scopus 로고    scopus 로고
    • Uncertain effects of rosiglitazone on the risk for myocardial infarction and cardiovascular death
    • [PMID: 17679700]
    • Diamond GA, Bax L, Kaul S. Uncertain effects of rosiglitazone on the risk for myocardial infarction and cardiovascular death. Ann Intern Med. 2007;147: 578-81. [PMID: 17679700]
    • (2007) Ann Intern Med , vol.147 , pp. 578-581
    • Diamond, G.A.1    Bax, L.2    Kaul, S.3
  • 19
    • 84882259426 scopus 로고    scopus 로고
    • Review Manager (RevMan) [computer program]. Version 5.2. Copenhagen, Denmark: Nordic Cochrane Center, Cochrane Collaboration
    • Review Manager (RevMan) [computer program]. Version 5.2. Copenhagen, Denmark: Nordic Cochrane Center, Cochrane Collaboration; 2012.
    • (2012)
  • 20
    • 84866003015 scopus 로고    scopus 로고
    • Dapagliflozin monotherapy in drugnaïve patients with diabetes: A randomized-controlled trial of low-dose range
    • [PMID: 22776824]
    • Bailey CJ, Iqbal N, T'joen C, List JF. Dapagliflozin monotherapy in drugnaïve patients with diabetes: a randomized-controlled trial of low-dose range. Diabetes Obes Metab. 2012;14:951-9. [PMID: 22776824]
    • (2012) Diabetes Obes Metab , vol.14 , pp. 951-959
    • Bailey, C.J.1    Iqbal, N.2    T'joen, C.3    List, J.F.4
  • 21
    • 77956921439 scopus 로고    scopus 로고
    • Dapagliflozin monotherapy in type 2 diabetic patients with inadequate glycemic control by diet and exercise: A randomized, double-blind, placebo-controlled, phase 3 trial
    • [PMID: 20566676]
    • Ferrannini E, Ramos SJ, Salsali A, Tang W, List JF. Dapagliflozin monotherapy in type 2 diabetic patients with inadequate glycemic control by diet and exercise: a randomized, double-blind, placebo-controlled, phase 3 trial. Diabetes Care. 2010;33:2217-24. [PMID: 20566676]
    • (2010) Diabetes Care , vol.33 , pp. 2217-2224
    • Ferrannini, E.1    Ramos, S.J.2    Salsali, A.3    Tang, W.4    List, J.F.5
  • 23
    • 84879795546 scopus 로고    scopus 로고
    • A phase IIb, randomized, placebo-controlled study of the SGLT2 inhibitor empagliflozin in patients with type 2 diabetes
    • [PMID: 23398530]
    • Ferrannini E, Seman L, Seewaldt-Becker E, Hantel S, Pinnetti S, Woerle HJ. A phase IIb, randomized, placebo-controlled study of the SGLT2 inhibitor empagliflozin in patients with type 2 diabetes. Diabetes Obes Metab. 2013;15: 721-8. [PMID: 23398530]
    • (2013) Diabetes Obes Metab , vol.15 , pp. 721-728
    • Ferrannini, E.1    Seman, L.2    Seewaldt-Becker, E.3    Hantel, S.4    Pinnetti, S.5    Woerle, H.J.6
  • 24
    • 84875204252 scopus 로고    scopus 로고
    • Safety and efficacy of empagliflozin as monotherapy or add-on to metformin in a 78-week open-label extension study in patients with type 2 diabetes [Abstract]
    • Woerle HJ, Ferrannini E, Berk A, Manun'ebo M, Pinnetti S, Broedl UC. Safety and efficacy of empagliflozin as monotherapy or add-on to metformin in a 78-week open-label extension study in patients with type 2 diabetes [Abstract]. Diabetes. 2012;61(Suppl 1A):LB13.
    • (2012) Diabetes , vol.61 , Issue.SUPPL. 1A
    • Woerle, H.J.1    Ferrannini, E.2    Berk, A.3    Manun'ebo, M.4    Pinnetti, S.5    Broedl, U.C.6
  • 25
    • 84876899238 scopus 로고    scopus 로고
    • Active-and placebo-controlled dose-finding study to assess the efficacy, safety, and tolerability of multiple doses of ipragliflozin in patients with type 2 diabetes mellitus
    • [PMID: 23276620]
    • Fonseca VA, Ferrannini E, Wilding JP, Wilpshaar W, Dhanjal P, Ball G, et al. Active-and placebo-controlled dose-finding study to assess the efficacy, safety, and tolerability of multiple doses of ipragliflozin in patients with type 2 diabetes mellitus. J Diabetes Complications. 2013;27:268-73. [PMID: 23276620]
    • (2013) J Diabetes Complications , vol.27 , pp. 268-273
    • Fonseca, V.A.1    Ferrannini, E.2    Wilding, J.P.3    Wilpshaar, W.4    Dhanjal, P.5    Ball, G.6
  • 26
    • 84861088227 scopus 로고    scopus 로고
    • Canagliflozin, a novel inhibitor of sodium glucose co-transporter 2 (SGLT2) improves glycemic control and reduces body weight in Japanese type 2 diabetes mellitus (T2DM) [Abstract]
    • Inagaki N, Kondo N, Iwasaki T, Maruyama N, Susuta Y, Sakai M, et al. Canagliflozin, a novel inhibitor of sodium glucose co-transporter 2 (SGLT2) improves glycemic control and reduces body weight in Japanese type 2 diabetes mellitus (T2DM) [Abstract]. Diabetes. 2011;60(Suppl 1):A274.
    • (2011) Diabetes , vol.60 , Issue.SUPPL. 1
    • Inagaki, N.1    Kondo, N.2    Iwasaki, T.3    Maruyama, N.4    Susuta, Y.5    Sakai, M.6
  • 27
    • 84876335563 scopus 로고    scopus 로고
    • Efficacy and safety of dapagliflozin as a monotherapy for type 2 diabetes mellitus in Japanese patients with inadequate glycaemic control: A phase II multicentre, randomized, double-blind, placebo-controlled trial
    • [PMID: 23194084]
    • Kaku K, Inoue S, Matsuoka O, Kiyosue A, Azuma H, Hayashi N, et al. Efficacy and safety of dapagliflozin as a monotherapy for type 2 diabetes mellitus in Japanese patients with inadequate glycaemic control: a phase II multicentre, randomized, double-blind, placebo-controlled trial. Diabetes Obes Metab. 2013; 15:432-40. [PMID: 23194084]
    • (2013) Diabetes Obes Metab , vol.15 , pp. 432-440
    • Kaku, K.1    Inoue, S.2    Matsuoka, O.3    Kiyosue, A.4    Azuma, H.5    Hayashi, N.6
  • 28
    • 79952993665 scopus 로고    scopus 로고
    • ASP1941, a novel, selective SGLT2 inhibitor, was effective and safe in Japanese healthy volunteers and patients with type 2 diabetes mellitus [Abstract
    • 75-OR
    • Kashiwagi A, Utsuno A, Kazuta K. ASP1941, a novel, selective SGLT2 inhibitor, was effective and safe in Japanese healthy volunteers and patients with type 2 diabetes mellitus [Abstract]. Diabetes. 2010;59(Suppl 1):75-OR.
    • (2010) Diabetes , vol.59 , Issue.SUPPL. 1
    • Kashiwagi, A.1    Utsuno, A.2    Kazuta, K.3
  • 29
    • 84864283546 scopus 로고    scopus 로고
    • Ipragliflozin improved glycaemic control with additional benefits of reductions of body weight and blood pressure in Japanese patients with type 2 diabetes mellitus: BRIGHTEN Study [Abstract]
    • Kashiwagi A, Takinami Y, Kazuta K, Yoshida S, Utsuno A, Nagase I. Ipragliflozin improved glycaemic control with additional benefits of reductions of body weight and blood pressure in Japanese patients with type 2 diabetes mellitus: BRIGHTEN Study [Abstract]. Diabetologia. 2011;54(Suppl 1):S68-9.
    • (2011) Diabetologia , vol.54 , Issue.SUPPL. 1
    • Kashiwagi, A.1    Takinami, Y.2    Kazuta, K.3    Yoshida, S.4    Utsuno, A.5    Nagase, I.6
  • 30
    • 65349196064 scopus 로고    scopus 로고
    • Sodium-glucose cotransport inhibition with dapagliflozin in type 2 diabetes
    • [PMID: 19114612]
    • List JF, Woo V, Morales E, Tang W, Fiedorek FT. Sodium-glucose cotransport inhibition with dapagliflozin in type 2 diabetes. Diabetes Care. 2009;32: 650-7. [PMID: 19114612]
    • (2009) Diabetes Care , vol.32 , pp. 650-657
    • List, J.F.1    Woo, V.2    Morales, E.3    Tang, W.4    Fiedorek, F.T.5
  • 31
    • 82455213037 scopus 로고    scopus 로고
    • Safety, pharmacokinetic, and pharmacodynamic profiles of ipragliflozin (ASP1941), a novel and selective inhibitor of sodium-dependent glucose cotransporter 2, in patients with type 2 diabetes mellitus
    • [PMID: 21854192]
    • Schwartz SL, Akinlade B, Klasen S, Kowalski D, Zhang W, Wilpshaar W. Safety, pharmacokinetic, and pharmacodynamic profiles of ipragliflozin (ASP1941), a novel and selective inhibitor of sodium-dependent glucose cotransporter 2, in patients with type 2 diabetes mellitus. Diabetes Technol Ther. 2011;13:1219-27. [PMID: 21854192]
    • (2011) Diabetes Technol Ther , vol.13 , pp. 1219-1227
    • Schwartz, S.L.1    Akinlade, B.2    Klasen, S.3    Kowalski, D.4    Zhang, W.5    Wilpshaar, W.6
  • 32
    • 84858258202 scopus 로고    scopus 로고
    • A novel potent and highly selective renal sodium-glocose co-transporter 2 (SGLT2) inhibitor, TS-071, improves glycaemic control and lowers body weight in Japanese patiens with type 2 diabetes mellitus [Abstract]
    • Seino Y, Sasaki T, Fukatsu A, Samukawa Y, Sakai S, Watanabe T. A novel potent and highly selective renal sodium-glocose co-transporter 2 (SGLT2) inhibitor, TS-071, improves glycaemic control and lowers body weight in Japanese patiens with type 2 diabetes mellitus [Abstract]. Diabetologia. 2011;54(Suppl 1):S68.
    • (2011) Diabetologia , vol.54 , Issue.SUPPL. 1
    • Seino, Y.1    Sasaki, T.2    Fukatsu, A.3    Samukawa, Y.4    Sakai, S.5    Watanabe, T.6
  • 33
    • 84875137677 scopus 로고    scopus 로고
    • Luseogliflozin (TS-071), a selective SGLT2 inhibitor, improves glycemic control and lowers body weight in Japanese patients with type 2 diabetes mellitus [Abstract]
    • Seino Y, Sasaki T, Fukatsu A, Samukawa Y, Sakai S, Watanabe T. Luseogliflozin (TS-071), a selective SGLT2 inhibitor, improves glycemic control and lowers body weight in Japanese patients with type 2 diabetes mellitus [Abstract]. Diabetes. 2012;61(Suppl 1):A266-7.
    • (2012) Diabetes , vol.61 , Issue.SUPPL. 1
    • Seino, Y.1    Sasaki, T.2    Fukatsu, A.3    Samukawa, Y.4    Sakai, S.5    Watanabe, T.6
  • 34
    • 84874291673 scopus 로고    scopus 로고
    • Efficacy and safety of canagliflozin monotherapy in subjects with type 2 diabetes mellitus inadequately controlled with diet and exercise
    • [PMID: 23279307]
    • Stenlöf K, Cefalu WT, Kim KA, Alba M, Usiskin K, Tong C, et al. Efficacy and safety of canagliflozin monotherapy in subjects with type 2 diabetes mellitus inadequately controlled with diet and exercise. Diabetes Obes Metab. 2013;15: 372-82. [PMID: 23279307]
    • (2013) Diabetes Obes Metab , vol.15 , pp. 372-382
    • Stenlöf, K.1    Cefalu, W.T.2    Kim, K.A.3    Alba, M.4    Usiskin, K.5    Tong, C.6
  • 36
    • 77953857048 scopus 로고    scopus 로고
    • Effect of dapagliflozin in patients with type 2 diabetes who have inadequate glycaemic control with metformin: A randomised, double-blind, placebo-controlled trial
    • [PMID: 20609968]
    • Bailey CJ, Gross JL, Pieters A, Bastien A, List JF. Effect of dapagliflozin in patients with type 2 diabetes who have inadequate glycaemic control with metformin: a randomised, double-blind, placebo-controlled trial. Lancet. 2010;375: 2223-33. [PMID: 20609968]
    • (2010) Lancet , vol.375 , pp. 2223-2233
    • Bailey, C.J.1    Gross, J.L.2    Pieters, A.3    Bastien, A.4    List, J.F.5
  • 37
    • 84873960885 scopus 로고    scopus 로고
    • Dapagliflozin add-on to metformin in type 2 diabetes inadequately controlled with metformin: A randomized, double-blind, placebo-controlled 102-week trial
    • [PMID: 23425012]
    • Bailey CJ, Gross JL, Hennicken D, Iqbal N, Mansfield TA, List JF. Dapagliflozin add-on to metformin in type 2 diabetes inadequately controlled with metformin: a randomized, double-blind, placebo-controlled 102-week trial. BMC Med. 2013;11:43. [PMID: 23425012]
    • (2013) BMC Med , vol.11 , pp. 43
    • Bailey, C.J.1    Gross, J.L.2    Hennicken, D.3    Iqbal, N.4    Mansfield, T.A.5    List, J.F.6
  • 38
    • 84879487485 scopus 로고    scopus 로고
    • Efficacy and safety of canagliflozin (CANA), a sodium glucose co-transporter 2 inhibitor (SGLT2), in older subjects with type 2 diabetes mellitus [Abstract]
    • Bode B, Stenlöf K, Sullivan D, Fung A, Usiskin K, Meininger G. Efficacy and safety of canagliflozin (CANA), a sodium glucose co-transporter 2 inhibitor (SGLT2), in older subjects with type 2 diabetes mellitus [Abstract]. Diabetologia. 2012;55(Suppl 1):S315.
    • (2012) Diabetologia , vol.55 , Issue.SUPPL. 1
    • Bode, B.1    Stenlöf, K.2    Sullivan, D.3    Fung, A.4    Usiskin, K.5    Meininger, G.6
  • 39
    • 84858020943 scopus 로고    scopus 로고
    • Effects of dapagliflozin on body weight, total fat mass, and regional adipose tissue distribution in patients with type 2 diabetes mellitus with inadequate glycemic control on metformin
    • [PMID: 22238392]
    • Bolinder J, Ljunggren O, Kullberg J, Johansson L, Wilding J, Langkilde AM, et al. Effects of dapagliflozin on body weight, total fat mass, and regional adipose tissue distribution in patients with type 2 diabetes mellitus with inadequate glycemic control on metformin. J Clin Endocrinol Metab. 2012;97:1020-31. [PMID: 22238392]
    • (2012) J Clin Endocrinol Metab , vol.97 , pp. 1020-1031
    • Bolinder, J.1    Ljunggren, O.2    Kullberg, J.3    Johansson, L.4    Wilding, J.5    Langkilde, A.M.6
  • 40
    • 84867142771 scopus 로고    scopus 로고
    • Dapagliflozin has no effect on markers of bone formation and resorption or bone mineral density in patients with inadequately controlled type 2 diabetes mellitus on metformin
    • [PMID: 22651373]
    • Ljunggren Ö, Bolinder J, Johansson L, Wilding J, Langkilde AM, Sjöström CD, et al. Dapagliflozin has no effect on markers of bone formation and resorption or bone mineral density in patients with inadequately controlled type 2 diabetes mellitus on metformin. Diabetes Obes Metab. 2012;14:990-9. [PMID: 22651373]
    • (2012) Diabetes Obes Metab , vol.14 , pp. 990-999
    • Ljunggren, O.1    Bolinder, J.2    Johansson, L.3    Wilding, J.4    Langkilde, A.M.5    Sjöström, C.D.6
  • 41
    • 84892485428 scopus 로고    scopus 로고
    • Dapagliflozin produces long-term reductions in body weight, waist circumference and total fat mass in patients with type 2 diabetes inadequately controlled on metformin [Abstract]
    • Bolinder J, Ljunggren O, Johansson L. Dapagliflozin produces long-term reductions in body weight, waist circumference and total fat mass in patients with type 2 diabetes inadequately controlled on metformin [Abstract]. Diabetologia. 2012;55(Suppl 1):S308.
    • (2012) Diabetologia , vol.55 , Issue.SUPPL. 1
    • Bolinder, J.1    Ljunggren, O.2    Johansson, L.3
  • 42
    • 84880012509 scopus 로고    scopus 로고
    • Dapagliflozin treatment for type 2 diabetes mellitus patients with comorbid cardiovascular disease and hypertension [Abstract]
    • Cefalu WT, Leiter LA, Debruin TW, Gausenilsson I, Sugg J, Parikh SJ. Dapagliflozin treatment for type 2 diabetes mellitus patients with comorbid cardiovascular disease and hypertension [Abstract]. Diabetes. 2012;61(Suppl 1): A271.
    • (2012) Diabetes , vol.61 , Issue.SUPPL. 1
    • Cefalu, W.T.1    Leiter, L.A.2    Debruin, T.W.3    Gausenilsson, I.4    Sugg, J.5    Parikh, S.J.6
  • 43
    • 84880005461 scopus 로고    scopus 로고
    • Efficacy and safety of canagliflozin, a sodium glucose co-transporter 2 inhibitor, compared with glimepiride in patients with type 2 diabetes on background metformin [Abstract]
    • Cefalu TW, Leiter LA, Niskanen L, Xie J, Millington D, Canovatchel W, et al. Efficacy and safety of canagliflozin, a sodium glucose co-transporter 2 inhibitor, compared with glimepiride in patients with type 2 diabetes on background metformin [Abstract]. Diabetes. 2012;61(Suppl 1A):LB10.
    • (2012) Diabetes , vol.61 , Issue.SUPPL. 1A
    • Cefalu, T.W.1    Leiter, L.A.2    Niskanen, L.3    Xie, J.4    Millington, D.5    Canovatchel, W.6
  • 44
    • 84860252876 scopus 로고    scopus 로고
    • Canagliflozin improves glycaemic control over 28 days in subjects with type 2 diabetes not optimally controlled on insulin
    • [PMID: 22226086]
    • Devineni D, Morrow L, Hompesch M, Skee D, Vandebosch A, Murphy J, et al. Canagliflozin improves glycaemic control over 28 days in subjects with type 2 diabetes not optimally controlled on insulin. Diabetes Obes Metab. 2012;14: 539-45. [PMID: 22226086]
    • (2012) Diabetes Obes Metab , vol.14 , pp. 539-545
    • Devineni, D.1    Morrow, L.2    Hompesch, M.3    Skee, D.4    Vandebosch, A.5    Murphy, J.6
  • 45
    • 83655184783 scopus 로고    scopus 로고
    • Remogliflozin etabonate, a selective inhibitor of the sodiumdependent transporter 2 reduces serum glucose in type 2 diabetes mellitus patients
    • [PMID: 21733056]
    • Dobbins RL, O'Connor-Semmes R, Kapur A, Kapitza C, Golor G, Mikoshiba I, et al. Remogliflozin etabonate, a selective inhibitor of the sodiumdependent transporter 2 reduces serum glucose in type 2 diabetes mellitus patients. Diabetes Obes Metab. 2012;14:15-22. [PMID: 21733056]
    • (2012) Diabetes Obes Metab , vol.14 , pp. 15-22
    • Dobbins, R.L.1    O'Connor-Semmes, R.2    Kapur, A.3    Kapitza, C.4    Golor, G.5    Mikoshiba, I.6
  • 46
    • 84875130718 scopus 로고    scopus 로고
    • Ipragliflozin reduces A1C and body weight in type 2 diabetes patients who have inadequate glycemic control on metformin alone: ILLUMINATE study [Abstract]
    • Goto K, Kashiwagi A, Kazuta K, Yoshida S, Ueyama E, Utsuno A. Ipragliflozin reduces A1C and body weight in type 2 diabetes patients who have inadequate glycemic control on metformin alone: ILLUMINATE study [Abstract]. Diabetes. 2012;61(Suppl 1):A269.
    • (2012) Diabetes , vol.61 , Issue.SUPPL. 1
    • Goto, K.1    Kashiwagi, A.2    Kazuta, K.3    Yoshida, S.4    Ueyama, E.5    Utsuno, A.6
  • 47
    • 84878947970 scopus 로고    scopus 로고
    • Safety, tolerability, pharmacokinetics and pharmacodynamics following 4 weeks' treatment with empagliflozin once daily in patients with type 2 diabetes
    • [PMID: 23356556]
    • Heise T, Seewaldt-Becker E, Macha S, Hantel S, Pinnetti S, Seman L, et al. Safety, tolerability, pharmacokinetics and pharmacodynamics following 4 weeks' treatment with empagliflozin once daily in patients with type 2 diabetes. Diabetes Obes Metab. 2013;15:613-21. [PMID: 23356556]
    • (2013) Diabetes Obes Metab , vol.15 , pp. 613-621
    • Heise, T.1    Seewaldt-Becker, E.2    Macha, S.3    Hantel, S.4    Pinnetti, S.5    Seman, L.6
  • 48
    • 84860218907 scopus 로고    scopus 로고
    • Dapagliflozin, metformin XR, or both: Initial pharmacotherapy for type 2 diabetes, a randomised controlled trial
    • [PMID: 22413962]
    • Henry RR, Murray AV, Marmolejo MH, Hennicken D, Ptaszynska A, List JF. Dapagliflozin, metformin XR, or both: initial pharmacotherapy for type 2 diabetes, a randomised controlled trial. Int J Clin Pract. 2012;66:446-56. [PMID: 22413962]
    • (2012) Int J Clin Pract , vol.66 , pp. 446-456
    • Henry, R.R.1    Murray, A.V.2    Marmolejo, M.H.3    Hennicken, D.4    Ptaszynska, A.5    List, J.F.6
  • 49
    • 84875206602 scopus 로고    scopus 로고
    • Dapagliflozin as add-on therapy to sitagliptin with or without metformin: A randomized, double-blind, placebocontrolled study [Abstract]
    • Jabbour S, Hardy E, Sugg J, Parikh S. Dapagliflozin as add-on therapy to sitagliptin with or without metformin: a randomized, double-blind, placebocontrolled study [Abstract]. Diabetes. 2012;61(Suppl 1):A275-6.
    • (2012) Diabetes , vol.61 , Issue.SUPPL. 1
    • Jabbour, S.1    Hardy, E.2    Sugg, J.3    Parikh, S.4
  • 50
    • 84874075297 scopus 로고    scopus 로고
    • Tofogliflozin, a novel and selective SGLT2 inhibitor improves glycemic control and lowers body weight in patients with type 2 diabetes mellitus inadequately controlled on stable metformin or diet and exercise alone [Abstract]
    • Kadowaki T, Ikeda S, Takano Y, Cynshi O, Christ AD, Boerlin V, et al. Tofogliflozin, a novel and selective SGLT2 inhibitor improves glycemic control and lowers body weight in patients with type 2 diabetes mellitus inadequately controlled on stable metformin or diet and exercise alone [Abstract]. Diabetes. 2012;61(Suppl 1):A22.
    • (2012) Diabetes , vol.61 , Issue.SUPPL. 1
    • Kadowaki, T.1    Ikeda, S.2    Takano, Y.3    Cynshi, O.4    Christ, A.D.5    Boerlin, V.6
  • 51
    • 84892486720 scopus 로고    scopus 로고
    • Ipragliflozin reduced HbA1c and body weight in Japanese type 2 diabetes patients who have inadequate glyceamic control on sulfonylurea or pioglitazone alone [Abstract]
    • Kashiwagi A, Shiga T, Akiyama N. Ipragliflozin reduced HbA1c and body weight in Japanese type 2 diabetes patients who have inadequate glyceamic control on sulfonylurea or pioglitazone alone [Abstract]. Diabetologia. 2012; 55(Suppl 1):S302-3.
    • (2012) Diabetologia , vol.55 , Issue.SUPPL. 1
    • Kashiwagi, A.1    Shiga, T.2    Akiyama, N.3
  • 52
    • 84871124567 scopus 로고    scopus 로고
    • Efficacy and safety of dapagliflozin in patients with type 2 diabetes and moderate renal impairment
    • Kohan DE, Fioretto P, List J, Tang W. Efficacy and safety of dapagliflozin in patients with type 2 diabetes and moderate renal impairment. J Am Soc Nephrol. 2011;22(Suppl):232A-3A.
    • (2011) J Am Soc Nephrol , vol.22 , Issue.SUPPL.
    • Kohan, D.E.1    Fioretto, P.2    List, J.3    Tang, W.4
  • 53
    • 67349275999 scopus 로고    scopus 로고
    • Dapagliflozin, a novel, selective SGLT2 inhibitor, improved glycemic control over 2 weeks in patients with type 2 diabetes mellitus
    • [PMID: 19129749]
    • Komoroski B, Vachharajani N, Feng Y, Li L, Kornhauser D, Pfister M. Dapagliflozin, a novel, selective SGLT2 inhibitor, improved glycemic control over 2 weeks in patients with type 2 diabetes mellitus. Clin Pharmacol Ther. 2009;85:513-9. [PMID: 19129749]
    • (2009) Clin Pharmacol Ther , vol.85 , pp. 513-519
    • Komoroski, B.1    Vachharajani, N.2    Feng, Y.3    Li, L.4    Kornhauser, D.5    Pfister, M.6
  • 54
    • 84879997537 scopus 로고    scopus 로고
    • Efficacy and safety of dapagliflozin for type 2 diabetes mellitus patients with a history of cardiovascular disease [Abstract]
    • Leiter LA, Cefalu WT, Debruin TW, Gausenilsson I, Sugg J, Parikh SJ. Efficacy and safety of dapagliflozin for type 2 diabetes mellitus patients with a history of cardiovascular disease [Abstract]. Diabetes. 2012;61(Suppl 1):A287.
    • (2012) Diabetes , vol.61 , Issue.SUPPL. 1
    • Leiter, L.A.1    Cefalu, W.T.2    Debruin, T.W.3    Gausenilsson, I.4    Sugg, J.5    Parikh, S.J.6
  • 55
    • 84879471749 scopus 로고    scopus 로고
    • Efficacy and safety of canagliflozin (CANA), an inhibitor of sodium glucose co-transporter 2 (SGLT2), added-on to insulin therapy -/- oral agents in type 2 diabetes [Abstract]
    • Matthews DR, Fulcher G, Perkovic V, DeZeeuw D, Mahaffey KW, Rosenstock J, et al. Efficacy and safety of canagliflozin (CANA), an inhibitor of sodium glucose co-transporter 2 (SGLT2), added-on to insulin therapy -/- oral agents in type 2 diabetes [Abstract]. Diabetologia. 2012;55(Suppl 1):S314-5.
    • (2012) Diabetologia , vol.55 , Issue.SUPPL. 1
    • Matthews, D.R.1    Fulcher, G.2    Perkovic, V.3    Dezeeuw, D.4    Mahaffey, K.W.5    Rosenstock, J.6
  • 56
    • 84892483216 scopus 로고    scopus 로고
    • Changes in insulin sensitivity as measured by glucose disposal rate and acute insulin secretion with the sodium glucose co-transporter 2 inhibitor dapagliflozin [Abstract]
    • Mudaliar S, Henry RR, Boden G, Smith S, Chalamandaris AG, Iqbal N, et al. Changes in insulin sensitivity as measured by glucose disposal rate and acute insulin secretion with the sodium glucose co-transporter 2 inhibitor dapagliflozin [Abstract]. Diabetologia. 2011;54(Suppl 1):S349.
    • (2011) Diabetologia , vol.54 , Issue.SUPPL. 1
    • Mudaliar, S.1    Henry, R.R.2    Boden, G.3    Smith, S.4    Chalamandaris, A.G.5    Iqbal, N.6
  • 57
    • 80155124676 scopus 로고    scopus 로고
    • Dapagliflozin versus glipizide as add-on therapy in patients with type 2 diabetes who have inadequate glycemic control with metformin: A randomized, 52-week, double-blind, active-controlled noninferiority trial
    • [PMID: 21816980]
    • Nauck MA, Del Prato S, Meier JJ, Durán-García S, Rohwedder K, Elze M, et al. Dapagliflozin versus glipizide as add-on therapy in patients with type 2 diabetes who have inadequate glycemic control with metformin: a randomized, 52-week, double-blind, active-controlled noninferiority trial. Diabetes Care. 2011;34:2015-22. [PMID: 21816980]
    • (2011) Diabetes Care , vol.34 , pp. 2015-2022
    • Nauck, M.A.1    Del Prato, S.2    Meier, J.J.3    Durán-García, S.4    Rohwedder, K.5    Elze, M.6
  • 58
    • 84871165283 scopus 로고    scopus 로고
    • Long-term efficacy and safety of add-on dapagliflozin vs add-on glipizidein patients with type 2 diabetes mellitus inadequately controlled with metformin: 2-year results [Abstract]
    • Del Prato S, Nauck MA, Rohwedder K, Theuerkauf A, Langkilde A, Parikh S. Long-term efficacy and safety of add-on dapagliflozin vs add-on glipizidein patients with type 2 diabetes mellitus inadequately controlled with metformin: 2-year results [Abstract]. Diabetologia. 2011;54(Suppl 1):S348.
    • (2011) Diabetologia , vol.54 , Issue.SUPPL. 1
    • Del Prato, S.1    Nauck, M.A.2    Rohwedder, K.3    Theuerkauf, A.4    Langkilde, A.5    Parikh, S.6
  • 59
    • 84871625141 scopus 로고    scopus 로고
    • The sodium glucose co-transporter-2 (SGLT2) inhibitor, PF04971729, provides multi-faceted improvements in diabetic patients inadequately controlled on metformin [Abstract]
    • Nucci G, Amin NB, Wang X, Lee DS, Rusnak JM. The sodium glucose co-transporter-2 (SGLT2) inhibitor, PF04971729, provides multi-faceted improvements in diabetic patients inadequately controlled on metformin [Abstract]. Diabetologia. 2011;54(Suppl 1):S347.
    • (2011) Diabetologia , vol.54 , Issue.SUPPL. 1
    • Nucci, G.1    Amin, N.B.2    Wang, X.3    Lee, D.S.4    Rusnak, J.M.5
  • 60
    • 84871634800 scopus 로고    scopus 로고
    • Efficacy and safety of BI 10773, a new sodium glucose cotransporter-2 (SGLT-2) inhibitor, in type 2 diabetes patients inadequately controlled on metformin [Abstract]
    • Rosenstock J, Jelaska A, Seman LJ, Pinnetti S, Hantel S, Woerle HJ. Efficacy and safety of BI 10773, a new sodium glucose cotransporter-2 (SGLT-2) inhibitor, in type 2 diabetes patients inadequately controlled on metformin [Abstract]. Diabetes. 2011;60(Suppl 1):A271.
    • (2011) Diabetes , vol.60 , Issue.SUPPL. 1
    • Rosenstock, J.1    Jelaska, A.2    Seman, L.J.3    Pinnetti, S.4    Hantel, S.5    Woerle, H.J.6
  • 61
    • 84862875221 scopus 로고    scopus 로고
    • Effects of dapagliflozin, an SGLT2 inhibitor, on HbA(1c), body weight, and hypoglycemia risk in patients with type 2 diabetes inadequately controlled on pioglitazone monotherapy
    • [PMID: 22446170]
    • Rosenstock J, Vico M, Wei L, Salsali A, List JF. Effects of dapagliflozin, an SGLT2 inhibitor, on HbA(1c), body weight, and hypoglycemia risk in patients with type 2 diabetes inadequately controlled on pioglitazone monotherapy. Diabetes Care. 2012;35:1473-8. [PMID: 22446170]
    • (2012) Diabetes Care , vol.35 , pp. 1473-1478
    • Rosenstock, J.1    Vico, M.2    Wei, L.3    Salsali, A.4    List, J.F.5
  • 62
    • 84861781220 scopus 로고    scopus 로고
    • Dose-ranging effects of canagliflozin, a sodium-glucose cotransporter 2 inhibitor, as add-on to metformin in subjects with type 2 diabetes
    • Canagliflozin DIA 2001 Study Group, [PMID: 22492586]
    • Rosenstock J, Aggarwal N, Polidori D, Zhao Y, Arbit D, Usiskin K, et al; Canagliflozin DIA 2001 Study Group. Dose-ranging effects of canagliflozin, a sodium-glucose cotransporter 2 inhibitor, as add-on to metformin in subjects with type 2 diabetes. Diabetes Care. 2012;35:1232-8. [PMID: 22492586]
    • (2012) Diabetes Care , vol.35 , pp. 1232-1238
    • Rosenstock, J.1    Aggarwal, N.2    Polidori, D.3    Zhao, Y.4    Arbit, D.5    Usiskin, K.6
  • 63
    • 84891784200 scopus 로고    scopus 로고
    • Canagliflozin compared with sitagliptin for patients with type 2 diabetes who do not have adequate glycemic control with metformin plus sulfonylurea: A 52-week randomized trial
    • [PMID: 23564919]
    • Schernthaner G, Gross JL, Rosenstock J, Guarisco M, Fu M, Yee J, et al. Canagliflozin compared with sitagliptin for patients with type 2 diabetes who do not have adequate glycemic control with metformin plus sulfonylurea: a 52-week randomized trial. Diabetes Care. 2013. [PMID: 23564919]
    • (2013) Diabetes Care
    • Schernthaner, G.1    Gross, J.L.2    Rosenstock, J.3    Guarisco, M.4    Fu, M.5    Yee, J.6
  • 64
    • 80052524011 scopus 로고    scopus 로고
    • Effect of dapagliflozin in patients with type 2 diabetes who have inadequate glycaemic control with glimepiride: A randomized, 24-week, double-blind, placebocontrolled trial
    • [PMID: 21672123]
    • Strojek K, Yoon KH, Hruba V, Elze M, Langkilde AM, Parikh S. Effect of dapagliflozin in patients with type 2 diabetes who have inadequate glycaemic control with glimepiride: a randomized, 24-week, double-blind, placebocontrolled trial. Diabetes Obes Metab. 2011;13:928-38. [PMID: 21672123]
    • (2011) Diabetes Obes Metab , vol.13 , pp. 928-938
    • Strojek, K.1    Yoon, K.H.2    Hruba, V.3    Elze, M.4    Langkilde, A.M.5    Parikh, S.6
  • 66
    • 69549095914 scopus 로고    scopus 로고
    • A study of dapagliflozin in patients with type 2 diabetes receiving high doses of insulin plus insulin sensitizers: Applicability of a novel insulin-independent treatment
    • [PMID: 19528367]
    • Wilding JP, Norwood P, T'joen C, Bastien A, List JF, Fiedorek FT. A study of dapagliflozin in patients with type 2 diabetes receiving high doses of insulin plus insulin sensitizers: applicability of a novel insulin-independent treatment. Diabetes Care. 2009;32:1656-62. [PMID: 19528367]
    • (2009) Diabetes Care , vol.32 , pp. 1656-1662
    • Wilding, J.P.1    Norwood, P.2    T'joen, C.3    Bastien, A.4    List, J.F.5    Fiedorek, F.T.6
  • 67
    • 84858323889 scopus 로고    scopus 로고
    • Dapagliflozin 006 Study Group. Long-term efficacy of dapagliflozin in patients with type 2 diabetes mellitus receiving high doses of insulin: A randomized trial
    • [PMID: 22431673]
    • Wilding JP, Woo V, Soler NG, Pahor A, Sugg J, Rohwedder K, et al; Dapagliflozin 006 Study Group. Long-term efficacy of dapagliflozin in patients with type 2 diabetes mellitus receiving high doses of insulin: a randomized trial. Ann Intern Med. 2012;156:405-15. [PMID: 22431673]
    • (2012) Ann Intern Med , vol.156 , pp. 405-415
    • Wilding, J.P.1    Woo, V.2    Soler, N.G.3    Pahor, A.4    Sugg, J.5    Rohwedder, K.6
  • 68
    • 84875186418 scopus 로고    scopus 로고
    • Long-term effectiveness of dapagliflozin over 104 weeks in patients with type 2 diabetes poorly controlled with insulin [Abstract]
    • Wilding JP, Woo VC, Rohwedder K, Sugg JE, Parikh SJ. Long-term effectiveness of dapagliflozin over 104 weeks in patients with type 2 diabetes poorly controlled with insulin [Abstract]. Diabetes. 2012;61(Suppl 1):A267-8.
    • (2012) Diabetes , vol.61 , Issue.SUPPL. 1
    • Wilding, J.P.1    Woo, V.C.2    Rohwedder, K.3    Sugg, J.E.4    Parikh, S.J.5
  • 69
    • 84875168195 scopus 로고    scopus 로고
    • Canagliflozin (CANA), a sodium glucose co-transporter 2 inhibitor, improves glycemic control and reduces body weight in subjects with type 2 diabetes (T2D) inadequately controlled with metformin (MET) and sulfonylurea (SU) [Abstract]
    • Wilding J, Mathieu C, Vercruysse F, Usiskin K, Deng L, Canovatchel W. Canagliflozin (CANA), a sodium glucose co-transporter 2 inhibitor, improves glycemic control and reduces body weight in subjects with type 2 diabetes (T2D) inadequately controlled with metformin (MET) and sulfonylurea (SU) [Abstract]. Diabetes. 2012;61(Suppl 1):A262.
    • (2012) Diabetes , vol.61 , Issue.SUPPL. 1
    • Wilding, J.1    Mathieu, C.2    Vercruysse, F.3    Usiskin, K.4    Deng, L.5    Canovatchel, W.6
  • 70
    • 84876344111 scopus 로고    scopus 로고
    • Efficacy and safety of ipragliflozin in patients with type 2 diabetes inadequately controlled on metformin: A dose-finding study
    • [PMID: 23163880]
    • Wilding JP, Ferrannini E, Fonseca VA, Wilpshaar W, Dhanjal P, Houzer A. Efficacy and safety of ipragliflozin in patients with type 2 diabetes inadequately controlled on metformin: a dose-finding study. Diabetes Obes Metab. 2013;15: 403-9. [PMID: 23163880]
    • (2013) Diabetes Obes Metab , vol.15 , pp. 403-409
    • Wilding, J.P.1    Ferrannini, E.2    Fonseca, V.A.3    Wilpshaar, W.4    Dhanjal, P.5    Houzer, A.6
  • 71
    • 84876311251 scopus 로고    scopus 로고
    • Efficacy and safety of canagliflozin in subjects with type 2 diabetes and chronic kidney disease
    • [PMID: 23464594]
    • Yale JF, Bakris G, Cariou B, Yue D, David-Neto E, Xi L, et al. Efficacy and safety of canagliflozin in subjects with type 2 diabetes and chronic kidney disease. Diabetes Obes Metab. 2013;15:463-73. [PMID: 23464594]
    • (2013) Diabetes Obes Metab , vol.15 , pp. 463-473
    • Yale, J.F.1    Bakris, G.2    Cariou, B.3    Yue, D.4    David-Neto, E.5    Xi, L.6
  • 73
    • 84882238654 scopus 로고    scopus 로고
    • Drawing inferences from incomplete data
    • eds. The Prevention and Treatment of Missing Data in Clinical Trials. Washington, DC: National Academies Pr
    • Drawing inferences from incomplete data. In: Panel of Handling Missing Data in Clinical Trials, National Research Council, eds. The Prevention and Treatment of Missing Data in Clinical Trials. Washington, DC: National Academies Pr; 2010:65-9.
    • (2010) Panel of Handling Missing Data In Clinical Trials, National Research Council , pp. 65-69
  • 74
    • 77953611072 scopus 로고    scopus 로고
    • Consolidated Standards of Reporting Trials Group. CONSORT 2010 Explanation and Elaboration: Updated guidelines for reporting parallel group randomised trials
    • [PMID: 20346624]
    • Moher D, Hopewell S, Schulz KF, Montori V, Gøtzsche PC, Devereaux PJ, et al; Consolidated Standards of Reporting Trials Group. CONSORT 2010 Explanation and Elaboration: Updated guidelines for reporting parallel group randomised trials. J Clin Epidemiol. 2010;63:e1-37. [PMID: 20346624]
    • (2010) J Clin Epidemiol , vol.63
    • Moher, D.1    Hopewell, S.2    Schulz, K.F.3    Montori, V.4    Gøtzsche, P.C.5    Devereaux, P.J.6
  • 76
    • 77955506490 scopus 로고    scopus 로고
    • Outcome reporting among drug trials registered in ClinicalTrials.gov
    • [PMID: 20679560]
    • Bourgeois FT, Murthy S, Mandl KD. Outcome reporting among drug trials registered in ClinicalTrials.gov. Ann Intern Med. 2010;153:158-66. [PMID: 20679560]
    • (2010) Ann Intern Med , vol.153 , pp. 158-166
    • Bourgeois, F.T.1    Murthy, S.2    Mandl, K.D.3
  • 77
    • 84882240750 scopus 로고    scopus 로고
    • Pub. L. No. 110-85, 121 Stat 823
    • Pub. L. No. 110-85, 121 Stat 823.
  • 78
    • 84882236392 scopus 로고    scopus 로고
    • Missing trial data-briefing notes. AllTrials.net. Accessed at, on 27 January 2013
    • Missing trial data-briefing notes. AllTrials.net. Accessed at www.alltrials.net /wp-content/uploads/2013/01/Missing-trials-briefing-note.pdf on 27 January 2013.
  • 79
    • 78751696572 scopus 로고    scopus 로고
    • Goodbye PubMed, hello raw data [Letter]
    • Godlee F. Goodbye PubMed, hello raw data [Letter]. BMJ. 2011;342:d212.
    • (2011) BMJ , vol.342
    • Godlee, F.1


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