Current Evidence and Future Directions of Tranexamic Acid Use, Efficacy, and Dosing for Major Surgical Procedures

Journal of Cardiothoracic and Vascular Anesthesia

Volumn 34, Issue 3, 2020, Pages 782-790

  Taam, Jason ^a   Yang, Qi Joy ^b   Pang, K Sandy ^b   Karanicolas, Paul ^a,c   Choi, Stephen ^a,c   Wasowicz, Marcin ^b,d   Jerath, Angela ^a,b,c,d,e  

^a SUNNYBROOK RESEARCH INSTITUTE   (Canada)

^b UNIVERSITY OF TORONTO   (Canada)

^c Canada   (Canada)

^d TORONTO GENERAL HOSPITAL   (Canada)

^e UNIVERSITY HEALTH NETWORK   (Canada)

Author keywords

antifibrinolytic; blood conservation; cardiac surgery; cardiopulmonary bypass; chronic kidney dysfunction; dose; fibrin; noncardiac surgery; pharmacokinetics; safety; seizures; Tranexamic acid; transfusion; trial

Indexed keywords

TRANEXAMIC ACID; ANTIFIBRINOLYTIC AGENT;

DRUG ACCUMULATION; DRUG CLEARANCE; DRUG EFFICACY; DRUG SAFETY; DRUG USE; HEART SURGERY; HUMAN; KIDNEY DISEASE; MAJOR SURGERY; OBSTETRIC OPERATION; OFF PUMP SURGERY; ON PUMP SURGERY; OPERATIVE BLOOD LOSS; OPTIMAL DRUG DOSE; ORGAN TRANSPLANTATION; ORTHOPEDIC SURGERY; PRIORITY JOURNAL; REVIEW; SURGICAL PATIENT; THORAX SURGERY; VASCULAR SURGERY; ADVERSE EVENT; BLOOD TRANSFUSION; CARDIOPULMONARY BYPASS;

ANTIFIBRINOLYTIC AGENTS; BLOOD LOSS, SURGICAL; BLOOD TRANSFUSION; CARDIAC SURGICAL PROCEDURES; CARDIOPULMONARY BYPASS; HUMANS; TRANEXAMIC ACID;

EID: 85071085546     PISSN: 10530770     EISSN: 15328422     Source Type: Journal    
DOI: 10.1053/j.jvca.2019.06.042     Document Type: Review

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