-
1
-
-
44349089188
-
A comparison of aprotinin and lysine analogues in high-risk cardiac surgery
-
Fergusson, D.A., Hébert, P.C., Mazer, C.D., et al. A comparison of aprotinin and lysine analogues in high-risk cardiac surgery. N Engl J Med 358 (2008), 2319–2331.
-
(2008)
N Engl J Med
, vol.358
, pp. 2319-2331
-
-
Fergusson, D.A.1
Hébert, P.C.2
Mazer, C.D.3
-
2
-
-
76249100902
-
High-dose tranexamic acid is associated with nonischemic clinical seizures in cardiac surgical patients
-
Murkin, J.M., Falter, F., Granton, J., et al. High-dose tranexamic acid is associated with nonischemic clinical seizures in cardiac surgical patients. Anesth Analg 110 (2010), 350–353.
-
(2010)
Anesth Analg
, vol.110
, pp. 350-353
-
-
Murkin, J.M.1
Falter, F.2
Granton, J.3
-
3
-
-
84055192250
-
High-dose tranexamic acid is an independent predictor of early seizure after cardiopulmonary bypass
-
Kalavrouziotis, D., Voisine, P., Mohammadi, S., et al. High-dose tranexamic acid is an independent predictor of early seizure after cardiopulmonary bypass. Ann Thorac Surg 93 (2012), 148–154.
-
(2012)
Ann Thorac Surg
, vol.93
, pp. 148-154
-
-
Kalavrouziotis, D.1
Voisine, P.2
Mohammadi, S.3
-
4
-
-
84892804137
-
The association between tranexamic acid and convulsive seizures after cardiac surgery: A multivariate analysis in 11 529 patients
-
Sharma, V., Katznelson, R., Jerath, A., et al. The association between tranexamic acid and convulsive seizures after cardiac surgery: A multivariate analysis in 11 529 patients. Anaesthesia 69 (2014), 124–130.
-
(2014)
Anaesthesia
, vol.69
, pp. 124-130
-
-
Sharma, V.1
Katznelson, R.2
Jerath, A.3
-
5
-
-
78751659459
-
Predictors and outcome of seizures after cardiac surgery: A multivariate analysis of 2,578 patients
-
Goldstone, A.B., Bronster, D.J., Anyanwu, A.C., et al. Predictors and outcome of seizures after cardiac surgery: A multivariate analysis of 2,578 patients. Ann Thorac Surg 91 (2011), 514–518.
-
(2011)
Ann Thorac Surg
, vol.91
, pp. 514-518
-
-
Goldstone, A.B.1
Bronster, D.J.2
Anyanwu, A.C.3
-
6
-
-
84856953707
-
Seizures following cardiac surgery: The impact of tranexamic acid and other risk factors
-
Manji, R.A., Grocott, H.P., Leake, J., et al. Seizures following cardiac surgery: The impact of tranexamic acid and other risk factors. Can J Anesth 59 (2012), 6–13.
-
(2012)
Can J Anesth
, vol.59
, pp. 6-13
-
-
Manji, R.A.1
Grocott, H.P.2
Leake, J.3
-
7
-
-
84871199216
-
Moderate dosage of tranexamic acid during cardiac surgery with cardiopulmonary bypass and convulsive seizures: Incidence and clinical outcome
-
Koster, A., Borgermann, J., Zittermann, A., et al. Moderate dosage of tranexamic acid during cardiac surgery with cardiopulmonary bypass and convulsive seizures: Incidence and clinical outcome. Br J Anaesth 110 (2013), 34–40.
-
(2013)
Br J Anaesth
, vol.110
, pp. 34-40
-
-
Koster, A.1
Borgermann, J.2
Zittermann, A.3
-
8
-
-
79954600429
-
High-dose tranexamic acid is related to increased risk of generalized seizures after aortic valve replacement
-
Keyl, C., Uhl, R., Beyersdorf, F., et al. High-dose tranexamic acid is related to increased risk of generalized seizures after aortic valve replacement. Eur J Cardiothorac Surg 39 (2011), e114–e121.
-
(2011)
Eur J Cardiothorac Surg
, vol.39
, pp. e114-e121
-
-
Keyl, C.1
Uhl, R.2
Beyersdorf, F.3
-
9
-
-
84856941122
-
Risk factors associated with postoperative seizures in patients undergoing cardiac surgery who received tranexamic acid: A case-control study
-
Montes, F.R., Pardo, D.F., Carreno, M., et al. Risk factors associated with postoperative seizures in patients undergoing cardiac surgery who received tranexamic acid: A case-control study. Ann Card Anaesth 15 (2012), 6–12.
-
(2012)
Ann Card Anaesth
, vol.15
, pp. 6-12
-
-
Montes, F.R.1
Pardo, D.F.2
Carreno, M.3
-
10
-
-
0029855977
-
Maintenance of therapeutic plasma aprotinin levels during prolonged cardiopulmonary bypass using a large dose regimen
-
Bennett-Guerrero, E., Sorohan, J.G., Howell, S.T., et al. Maintenance of therapeutic plasma aprotinin levels during prolonged cardiopulmonary bypass using a large dose regimen. Anesth Analg 83 (1996), 1189–1192.
-
(1996)
Anesth Analg
, vol.83
, pp. 1189-1192
-
-
Bennett-Guerrero, E.1
Sorohan, J.G.2
Howell, S.T.3
-
11
-
-
0033396840
-
Hemostatic effects of aprotinin, tranexamic acid and epsilon-aminocaproic acid in primary cardiac surgery
-
Casati, V., Guzzon, D., Oppizzi, M., et al. Hemostatic effects of aprotinin, tranexamic acid and epsilon-aminocaproic acid in primary cardiac surgery. Ann Thorac Surg 68 (1999), 2252–2256.
-
(1999)
Ann Thorac Surg
, vol.68
, pp. 2252-2256
-
-
Casati, V.1
Guzzon, D.2
Oppizzi, M.3
-
12
-
-
84870526551
-
Tranexamic acid concentrations associated with human seizures inhibit glycine receptors
-
Lecker, I., Wang, D.S., Romaschin, A.D., et al. Tranexamic acid concentrations associated with human seizures inhibit glycine receptors. J Clin Invest 122 (2012), 4654–4666.
-
(2012)
J Clin Invest
, vol.122
, pp. 4654-4666
-
-
Lecker, I.1
Wang, D.S.2
Romaschin, A.D.3
-
13
-
-
0026794981
-
Cardiopulmonary bypass and the blood-brain barrier. An experimental study
-
Gillinov, A.M., Davis, E.A., Curtis, W.E., et al. Cardiopulmonary bypass and the blood-brain barrier. An experimental study. J Thorac Cardiovasc Surg 104 (1992), 1110–1115.
-
(1992)
J Thorac Cardiovasc Surg
, vol.104
, pp. 1110-1115
-
-
Gillinov, A.M.1
Davis, E.A.2
Curtis, W.E.3
-
14
-
-
84956574965
-
Tranexamic acid-associated seizures: Causes and treatment
-
Lecker, L., Wang, D.S., Whissell, P.D., et al. Tranexamic acid-associated seizures: Causes and treatment. Ann Neuro 79 (2016), 18–26.
-
(2016)
Ann Neuro
, vol.79
, pp. 18-26
-
-
Lecker, L.1
Wang, D.S.2
Whissell, P.D.3
-
15
-
-
0036164926
-
Epileptic seizures following cortical application of fibrin sealants containing tranexamic acid in rats
-
Schlag, M.G., Hopf, R., Zifko, U., et al. Epileptic seizures following cortical application of fibrin sealants containing tranexamic acid in rats. Acta Neurochir (Wien) 144 (2002), 63–69.
-
(2002)
Acta Neurochir (Wien)
, vol.144
, pp. 63-69
-
-
Schlag, M.G.1
Hopf, R.2
Zifko, U.3
-
16
-
-
0037216105
-
The effect of short-term antifibrinolytic therapy on experimental vasospasm
-
Iplikcioglu, A.C., Berkman, M.Z., The effect of short-term antifibrinolytic therapy on experimental vasospasm. Surg Neurol 59 (2003), 10–16.
-
(2003)
Surg Neurol
, vol.59
, pp. 10-16
-
-
Iplikcioglu, A.C.1
Berkman, M.Z.2
-
17
-
-
84895486195
-
Tranexamic acid impairs ƴ-aminobutyric acid receptor type A-mediated synaptic transmission in the murine amygdala: A potential mechanism for drug-induced seizures?
-
Kratzer, S., Irl, H., Mattusch, C., et al. Tranexamic acid impairs ƴ-aminobutyric acid receptor type A-mediated synaptic transmission in the murine amygdala: A potential mechanism for drug-induced seizures?. Anesthesiology 120 (2014), 639–649.
-
(2014)
Anesthesiology
, vol.120
, pp. 639-649
-
-
Kratzer, S.1
Irl, H.2
Mattusch, C.3
-
18
-
-
77955117750
-
Mortality associated with administration of high-dose tranexamic acid and aprotinin in primary open-heart procedures: A retrospective analysis
-
Sander, M., Spies, C.D., Martiny, V., et al. Mortality associated with administration of high-dose tranexamic acid and aprotinin in primary open-heart procedures: A retrospective analysis. Crit Care, 14, 2010, R148.
-
(2010)
Crit Care
, vol.14
, pp. R148
-
-
Sander, M.1
Spies, C.D.2
Martiny, V.3
-
19
-
-
58149293358
-
The risks of aprotinin and tranexamic acid in cardiac surgery: A one-year follow-up of 1188 consecutive patients
-
Martin, K., Wiesner, G., Breuer, T., et al. The risks of aprotinin and tranexamic acid in cardiac surgery: A one-year follow-up of 1188 consecutive patients. Anesth Analg 107 (2008), 1783–1790.
-
(2008)
Anesth Analg
, vol.107
, pp. 1783-1790
-
-
Martin, K.1
Wiesner, G.2
Breuer, T.3
-
20
-
-
84867193761
-
Pharmacokinetics of tranexamic acid in patients undergoing cardiac surgery with use of cardiopulmonary bypass
-
Sharma, V., Fan, J., Jerath, A., et al. Pharmacokinetics of tranexamic acid in patients undergoing cardiac surgery with use of cardiopulmonary bypass. Anaesthesia 67 (2012), 1242–1250.
-
(2012)
Anaesthesia
, vol.67
, pp. 1242-1250
-
-
Sharma, V.1
Fan, J.2
Jerath, A.3
-
21
-
-
84870523169
-
Understanding the TXA seizure connection
-
Schwinn, D.A., Mackensen, G.B., Brown, E.N., Understanding the TXA seizure connection. J Clin Invest 122 (2012), 4339–4341.
-
(2012)
J Clin Invest
, vol.122
, pp. 4339-4341
-
-
Schwinn, D.A.1
Mackensen, G.B.2
Brown, E.N.3
-
22
-
-
0028797713
-
The dose-response relationship of tranexamic acid
-
Horrow, J.C., Van Riper, D.F., Strong, M.D., et al. The dose-response relationship of tranexamic acid. Anesthesiology 82 (1995), 383–392.
-
(1995)
Anesthesiology
, vol.82
, pp. 383-392
-
-
Horrow, J.C.1
Van Riper, D.F.2
Strong, M.D.3
-
23
-
-
84927923934
-
Effect of two doses of tranexamic acid on fibrinolysis evaluated by thromboelastography during cardiac surgery: A randomised, controlled study
-
Faraoni, D., Cacheux, C., Van Aelbrouck, C., et al. Effect of two doses of tranexamic acid on fibrinolysis evaluated by thromboelastography during cardiac surgery: A randomised, controlled study. Eur J Anaesthesiol 31 (2014), 491–498.
-
(2014)
Eur J Anaesthesiol
, vol.31
, pp. 491-498
-
-
Faraoni, D.1
Cacheux, C.2
Van Aelbrouck, C.3
-
24
-
-
84895441383
-
Comparison of two doses of tranexamic acid in adults undergoing cardiac surgery with cardiopulmonary bypass
-
Sigaut, S., Iremey, B., Ouattara, A., et al. Comparison of two doses of tranexamic acid in adults undergoing cardiac surgery with cardiopulmonary bypass. Anesthesiology 120 (2014), 590–600.
-
(2014)
Anesthesiology
, vol.120
, pp. 590-600
-
-
Sigaut, S.1
Iremey, B.2
Ouattara, A.3
|