메뉴 건너뛰기




Volumn 110, Issue 2, 2010, Pages 350-353

High-dose tranexamic acid is associated with nonischemic clinical seizures in cardiac surgical patients

Author keywords

[No Author keywords available]

Indexed keywords

TRANEXAMIC ACID; ANTIFIBRINOLYTIC AGENT;

EID: 76249100902     PISSN: 00032999     EISSN: None     Source Type: Journal    
DOI: 10.1213/ANE.0b013e3181c92b23     Document Type: Article
Times cited : (293)

References (31)
  • 2
    • 36549084598 scopus 로고    scopus 로고
    • Increased mortality, postoperative morbidity, and cost after red blood cell transfusion in patients having cardiac surgery
    • Murphy GJ, Reeves BC, Rogers CA, Rizvi SI, Culliford L, Angelini GD. Increased mortality, postoperative morbidity, and cost after red blood cell transfusion in patients having cardiac surgery. Circulation 2007;116:2544-2552
    • (2007) Circulation , vol.116 , pp. 2544-2552
    • Murphy, G.J.1    Reeves, B.C.2    Rogers, C.A.3    Rizvi, S.I.4    Culliford, L.5    Angelini, G.D.6
  • 3
    • 34247269097 scopus 로고    scopus 로고
    • Perioperative blood transfusion and blood conservation in cardiac surgery: The Society of Thoracic Surgeons and the Society of Cardiovascular Anesthesiologists clinical practice guideline
    • Society of Thoracic Surgeons Blood Conservation Guideline Task Force. Society of Cardiovascular Anesthesiologists Special Task Force on Blood Transfusion, Spiess BD, Shore-Lesserson L, Stafford-Smith M, Mazer CD, Bennett-Guerrero E, Hill SE, Body S
    • Society of Thoracic Surgeons Blood Conservation Guideline Task Force, Ferraris VA, Ferraris SP, Saha SP, Hessel EA II, Haan CK, Royston BD, Bridges CR, Higgins RS, Despotis G, Brown JR; Society of Cardiovascular Anesthesiologists Special Task Force on Blood Transfusion, Spiess BD, Shore-Lesserson L, Stafford-Smith M, Mazer CD, Bennett-Guerrero E, Hill SE, Body S. Perioperative blood transfusion and blood conservation in cardiac surgery: the Society of Thoracic Surgeons and The Society of Cardiovascular Anesthesiologists clinical practice guideline. Ann Thorac Surg 2007;83:S27-86
    • (2007) Ann Thorac Surg , vol.83
    • Ferraris, V.A.1    Ferraris, S.P.2    Saha, S.P.3    Hessel II, E.A.4    Haan, C.K.5    Royston, B.D.6    Bridges, C.R.7    Higgins, R.S.8    Despotis, G.9    Brown, J.R.10
  • 5
    • 85031339517 scopus 로고    scopus 로고
    • Available at
    • Available at: http://www.fda.gov/CDER/DRUG/infopage/ aprotinin/default. htm
  • 6
    • 85031343551 scopus 로고    scopus 로고
    • Available at
    • Available at: http://www.pharmacists.ca/content/hcp/tools/ drugnews/discontinued.htm
  • 7
    • 85031332033 scopus 로고    scopus 로고
    • Available at
    • Available at: http://www.medsafe.govt.nz/Profs/adverse/ Minutes125.htm#3.1
  • 8
    • 0031415922 scopus 로고    scopus 로고
    • Drugs to minimize perioperative blood loss in cardiac surgery: Meta-analyses using perioperative blood transfusion as the outcome. The International Study of Peri-operative Transfusion (ISPOT) Investigators
    • Laupacis A, Fergusson D. Drugs to minimize perioperative blood loss in cardiac surgery: meta-analyses using perioperative blood transfusion as the outcome. The International Study of Peri-operative Transfusion (ISPOT) Investigators. Anesth Analg 1997;85:1258-1267
    • (1997) Anesth Analg , vol.85 , pp. 1258-1267
    • Laupacis, A.1    Fergusson, D.2
  • 9
    • 33744509867 scopus 로고    scopus 로고
    • Morbidity and mortality risk associated with red blood cell and blood-component transfusion in isolated coronary artery bypass grafting
    • Koch CG, Li L, Duncan AI, Mihaljevic T, Cosgrove DM, Loop FD, Starr NJ, Blackstone EH. Morbidity and mortality risk associated with red blood cell and blood-component transfusion in isolated coronary artery bypass grafting. Crit Care Med 2006;34:1608-1616
    • (2006) Crit Care Med , vol.34 , pp. 1608-1616
    • Koch, C.G.1    Li, L.2    Duncan, A.I.3    Mihaljevic, T.4    Cosgrove, D.M.5    Loop, F.D.6    Starr, N.J.7    Blackstone, E.H.8
  • 13
    • 31344467254 scopus 로고    scopus 로고
    • The risk associated with aprotinin in cardiac surgery
    • Multicenter Study of Perioperative Ischemia Research group; Ischemia Research and Education Foundation
    • Mangano DT, Tudor IC, Dietzel C; Multicenter Study of Perioperative Ischemia Research group; Ischemia Research and Education Foundation. The risk associated with aprotinin in cardiac surgery. N Engl J Med 2006;354:353-365
    • (2006) N Engl J Med , vol.354 , pp. 353-365
    • Mangano, D.T.1    Tudor, I.C.2    Dietzel, C.3
  • 14
    • 58149293358 scopus 로고    scopus 로고
    • The risks of aprotinin and tranexamic acid in cardiac surgery: A one-year follow-up of 1188 consecutive patients
    • Martin K, Wiesner G, Breuer T, Lange R, Tassani P. The risks of aprotinin and tranexamic acid in cardiac surgery: A one-year follow-up of 1188 consecutive patients. Anesth Analg 2008;107: 1783-1790
    • (2008) Anesth Analg , vol.107 , pp. 1783-1790
    • Martin, K.1    Wiesner, G.2    Breuer, T.3    Lange, R.4    Tassani, P.5
  • 16
    • 85031331994 scopus 로고    scopus 로고
    • Available at
    • Available at: http://www.cas.ca/annual-meeting/abstracts- and-refresher/poster-discussions/1-16/613047.pdf
  • 17
    • 0037219816 scopus 로고    scopus 로고
    • Convulsions and refractory ventricular fibrillation after intrathecal injection of a massive dose of tranexamic acid
    • Yeh HM, Lau HP, Lin PL, Sun WZ, Mok MS. Convulsions and refractory ventricular fibrillation after intrathecal injection of a massive dose of tranexamic acid. Anesthesiology 2003;98:270-272
    • (2003) Anesthesiology , vol.98 , pp. 270-272
    • Yeh, H.M.1    Lau, H.P.2    Lin, P.L.3    Sun, W.Z.4    Mok, M.S.5
  • 18
    • 0024031612 scopus 로고
    • Accidental injection of tranexamic acid (Transamin) during spinal anesthesia
    • Wong JO, Yang SF, Tsai MH. [Accidental injection of tranexamic acid (Transamin) during spinal anesthesia]. Ma Zui Xue Za Zhi 1988;26:249-252
    • (1988) Ma Zui Xue Za Zhi , vol.26 , pp. 249-252
    • Wong, J.O.1    Yang, S.F.2    Tsai, M.H.3
  • 20
    • 33847678904 scopus 로고    scopus 로고
    • Death after an inadvertent intrathecal injection of tranexamic acid
    • Garcha PS, Mohan CV, Sharma RM. Death after an inadvertent intrathecal injection of tranexamic acid. Anesth Analg 2007;104:241-242
    • (2007) Anesth Analg , vol.104 , pp. 241-242
    • Garcha, P.S.1    Mohan, C.V.2    Sharma, R.M.3
  • 21
    • 0026511647 scopus 로고
    • Cerebral blood flow in patients with a subarachnoid haemorrhage during treatment with tranexamic acid
    • Tsementzis SA, Meyer CH, Hitchcock ER. Cerebral blood flow in patients with a subarachnoid haemorrhage during treatment with tranexamic acid. Neurochirurgia (Stuttg) 1992;35:74-78
    • (1992) Neurochirurgia (Stuttg) , vol.35 , pp. 74-78
    • Tsementzis, S.A.1    Meyer, C.H.2    Hitchcock, E.R.3
  • 22
    • 0025129288 scopus 로고
    • Benefits and risks of antifibrinolytic therapy in the management of ruptured intracranial aneurysms. A double-blind placebo-controlled study
    • Tsementzis SA, Hitchcock ER, Meyer CH. Benefits and risks of antifibrinolytic therapy in the management of ruptured intracranial aneurysms. A double-blind placebo-controlled study. Acta Neurochir (Wien) 1990;102:1-10
    • (1990) Acta Neurochir (Wien) , vol.102 , pp. 1-10
    • Tsementzis, S.A.1    Hitchcock, E.R.2    Meyer, C.H.3
  • 23
    • 0037216105 scopus 로고    scopus 로고
    • The effect of short-term antifibrinolytic therapy on experimental vasospasm
    • discussion 16-17
    • Iplikcioglu AC, Berkman MZ. The effect of short-term antifibrinolytic therapy on experimental vasospasm. Surg Neurol 2003;59:10-6; discussion 16-17
    • (2003) Surg Neurol , vol.59 , pp. 10-16
    • Iplikcioglu, A.C.1    Berkman, M.Z.2
  • 24
    • 0036196828 scopus 로고    scopus 로고
    • Tranexamic acid, a widely used antifibrinolytic agent, causes convulsions by a gamma-aminobutyric acid(A) receptor antagonistic effect
    • Furtmuller R, Schlag MG, Berger M, Hopf R, Huck S, Sieghart W, Redl H. Tranexamic acid, a widely used antifibrinolytic agent, causes convulsions by a gamma-aminobutyric acid(A) receptor antagonistic effect. J Pharmacol Exp Ther 2002; 301:168-173
    • (2002) J Pharmacol Exp Ther , vol.301 , pp. 168-173
    • Furtmuller, R.1    Schlag, M.G.2    Berger, M.3    Hopf, R.4    Huck, S.5    Sieghart, W.6    Redl, H.7
  • 25
    • 0033662348 scopus 로고    scopus 로고
    • Convulsive seizures following subdural application of fibrin sealant containing tranexamic acid in a rat model
    • Schlag MG, Hopf R, Redl H. Convulsive seizures following subdural application of fibrin sealant containing tranexamic acid in a rat model. Neurosurgery 2000;47:1463-1467
    • (2000) Neurosurgery , vol.47 , pp. 1463-1467
    • Schlag, M.G.1    Hopf, R.2    Redl, H.3
  • 27
    • 0018831107 scopus 로고
    • Cerebral complication of antifibrinolytic therapy in the treatment of ruptured intracranial aneurysm: Animal experiment and a review of literature
    • Yamaura A, Nakamura T, Makino H, Hagihara Y. Cerebral complication of antifibrinolytic therapy in the treatment of ruptured intracranial aneurysm: animal experiment and a review of literature. Eur Neurol 1980;19:77-84
    • (1980) Eur Neurol , vol.19 , pp. 77-84
    • Yamaura, A.1    Nakamura, T.2    Makino, H.3    Hagihara, Y.4
  • 28
    • 0019826385 scopus 로고
    • Determination of tranexamic acid (AMCA) and fibrin/fibrinogen degradation products in cerebrospinal fluid after aneurysmal subarachnoid haemorrhage
    • DOI 10.1007/BF01401679
    • Fodstad H, Pilbrant A, Schannong M, Strömberg S. Determination of tranexamic acid (AMCA) and fibrin/fibrinogen degradation products in cerebrospinal fluid after aneurysmal subarachnoid haemorrhage. Acta Neurochir (Wien) 1981; 58:1-13 (Pubitemid 11030618)
    • (1981) Acta Neurochirurgica , vol.58 , Issue.1-2 , pp. 1-13
    • Fodstad, H.1    Pilbrant, A.2    Schannong, M.3    Stromberg, S.4
  • 29
    • 0036164926 scopus 로고    scopus 로고
    • Epileptic seizures following cortical application of fibrin sealants containing tranexamic acid in rats
    • Schlag MG, Hopf R, Zifko U, Redl H. Epileptic seizures following cortical application of fibrin sealants containing tranexamic acid in rats. Acta Neurochir (Wien) 2002;144:63-69
    • (2002) Acta Neurochir (Wien) , vol.144 , pp. 63-69
    • Schlag, M.G.1    Hopf, R.2    Zifko, U.3    Redl, H.4
  • 30
    • 4644260166 scopus 로고    scopus 로고
    • Increased transcription factor expression and permeability of the blood brain barrier associated with cardiopulmonary bypass in lambs
    • Cavaglia M, Seshadri SG, Marchand JE, Ochocki CL, Mee RB, Bokesch PM. Increased transcription factor expression and permeability of the blood brain barrier associated with cardiopulmonary bypass in lambs. Ann Thorac Surg 2004;78:1418-1425
    • (2004) Ann Thorac Surg , vol.78 , pp. 1418-1425
    • Cavaglia, M.1    Seshadri, S.G.2    Marchand, J.E.3    Ochocki, C.L.4    Mee, R.B.5    Bokesch, P.M.6
  • 31
    • 0024423534 scopus 로고
    • Convulsions induced by aminocaproic acid infusion
    • Shinar E, Rabinovici R, Heyman A, Kluger Y. Convulsions induced by aminocaproic acid infusion. DICP 1989;23:780-781
    • (1989) DICP , vol.23 , pp. 780-781
    • Shinar, E.1    Rabinovici, R.2    Heyman, A.3    Kluger, Y.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.