Contemporary circulating enterovirus D68 strains infect and undergo retrograde axonal transport in spinal motor neurons independent of sialic acid

Journal of Virology

Volumn 93, Issue 16, 2019, Pages

  Hixon, Alison M ^a   Clarke, Penny ^b   Tyler, Kenneth L ^a,b  

^a UNIVERSITY OF COLORADO   (United States)

^b UNIVERSITY OF COLORADO SCHOOL OF MEDICINE   (United States)

Author keywords

Enterovirus D68; ICAM 5; Motor neuron; Retrograde transport; Sialic acid

Indexed keywords

GLYCOPROTEIN; INTERCELLULAR ADHESION MOLECULE 5; SIALIC ACID; UNCLASSIFIED DRUG; VIRUS RECEPTOR; CELL ADHESION MOLECULE; ICAM5 PROTEIN, HUMAN; N ACETYLNEURAMINIC ACID; NERVE PROTEIN;

ADULT; ANIMAL CELL; ARTICLE; AXON; CELL BODY; CELL DEATH; CONTROLLED STUDY; ENTEROVIRUS D68; FEMALE; HUMAN; HUMAN CELL; HUMAN TISSUE; INDUCED PLURIPOTENT STEM CELL; LIMIT OF DETECTION; MICROFLUIDIC ANALYSIS; MOTONEURON; MOUSE; NERVE FIBER TRANSPORT; NEWBORN; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; SPINAL CORD NERVE CELL; VIRUS LOAD; VIRUS STRAIN; ANIMAL; CENTRAL NERVOUS SYSTEM INFECTION; CYTOLOGY; DISEASE MODEL; ENTEROVIRUS D; ENTEROVIRUS INFECTION; HOST PATHOGEN INTERACTION; METABOLISM; MYELITIS; NEUROMUSCULAR DISEASE; PARALYSIS; PHYSIOLOGY; VIROLOGY;

ANIMALS; AXONAL TRANSPORT; CELL ADHESION MOLECULES; CENTRAL NERVOUS SYSTEM VIRAL DISEASES; DISEASE MODELS, ANIMAL; ENTEROVIRUS D, HUMAN; ENTEROVIRUS INFECTIONS; HOST-PATHOGEN INTERACTIONS; HUMANS; INDUCED PLURIPOTENT STEM CELLS; MICE; MOTOR NEURONS; MYELITIS; N-ACETYLNEURAMINIC ACID; NERVE TISSUE PROTEINS; NEUROMUSCULAR DISEASES; PARALYSIS;

EID: 85070732121     PISSN: 0022538X     EISSN: 10985514     Source Type: Journal    
DOI: 10.1128/JVI.00578-19     Document Type: Article

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