Enterovirus 71 can directly infect the brainstem via cranial nerves and infection can be ameliorated by passive immunization

Journal of Neuropathology and Experimental Neurology

Volumn 73, Issue 11, 2014, Pages 999-1008

  Tan, Soon Hao ^a   Ong, Kien Chai ^a   Wong, Kum Thong ^a  

^a UNIVERSITY OF MALAYA   (Malaysia)

Author keywords

Brainstem infections; Cranial nerves; Enterovirus 71; Passive immunization; Retrograde axonal transport; Viral transmission

Indexed keywords

FORMALDEHYDE INACTIVATED VIRUS VACCINE; HYPERIMMUNE GLOBULIN; INACTIVATED VIRUS VACCINE; RNA; UNCLASSIFIED DRUG; VIRUS ANTIGEN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BRAIN STEM; BRAIN STEM INFECTION; CENTRAL NERVOUS SYSTEM INFECTION; CONTROLLED STUDY; CRANIAL NERVE; DISEASE SEVERITY; DRUG MEGADOSE; ENTEROVIRUS 71; ENTEROVIRUS INFECTION; EXPERIMENTAL MODEL; FACE MUSCLE; FACIAL NERVE NUCLEUS; IMMUNOHISTOCHEMISTRY; IN SITU HYBRIDIZATION; JAW MUSCLE; LOW DRUG DOSE; MEDULLA OBLONGATA; MICROSCOPY; MORTALITY; MOUSE; NONHUMAN; PASSIVE IMMUNIZATION; RETICULAR FORMATION; RETROGRADE NERVE FIBER TRANSPORT; SPINAL CORD; TRIGEMINAL NUCLEUS; VIRUS TITRATION; ANIMAL; ENTEROVIRUS; ENTEROVIRUS INFECTIONS; INSTITUTE FOR CANCER RESEARCH MOUSE; ISOLATION AND PURIFICATION; METABOLISM; NERVE FIBER TRANSPORT; PHYSIOLOGY; PROCEDURES; VIROLOGY;

ANIMALS; AXONAL TRANSPORT; BRAIN STEM; CRANIAL NERVES; ENTEROVIRUS A, HUMAN; ENTEROVIRUS INFECTIONS; IMMUNIZATION, PASSIVE; MICE; MICE, INBRED ICR;

EID: 84916236434     PISSN: 00223069     EISSN: 15546578     Source Type: Journal    
DOI: 10.1097/NEN.0000000000000122     Document Type: Article

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