A neonatal mouse model of Enterovirus D68 infection induces both interstitial pneumonia and acute flaccid myelitis

Antiviral Research

Volumn 161, Issue , 2019, Pages 108-115

  Sun, Shiyang ^a,b   Bian, Lianlian ^b   Gao, Fan ^b   Du, Ruixiao ^b   Hu, Yalin ^c   Fu, Ying ^b   Su, Yao ^b   Wu, Xing ^b   Mao, Qunying ^b   Liang, Zhenglun ^b  

^a INSTITUTE OF MEDICINAL BIOTECHNOLOGY   (China)

^b NATIONAL INSTITUTES FOR FOOD AND DRUG CONTROL   (China)

^c Hualan Biological Engineering Inc   (China)

Author keywords

Acute flaccid myelitis; Enterovirus D68; Infection; Interstitial pneumonia; Neonatal mouse model

Indexed keywords

MATERNAL ANTIBODY; ACUTE FLACCID MYELITIS; VIRUS ANTIBODY;

ACUTE DISEASE; ACUTE FLACCID MYELITIS; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; CROSS PROTECTION; ENTEROVIRUS D68; ENTEROVIRUS D68 INFECTION; ENTEROVIRUS INFECTION; FEMALE; HISTOPATHOLOGY; IMMUNOHISTOCHEMISTRY; INTERSTITIAL PNEUMONIA; LUNG ALVEOLUS WALL; MOUSE; MUSCLE NECROSIS; MYELITIS; NEWBORN; NEWBORN DEATH; NONHUMAN; PARALYSIS; PRIORITY JOURNAL; REAL TIME POLYMERASE CHAIN REACTION; SPINAL CORD DISEASE; TACHYPNEA; VIRAL TROPISM; VIRUS LOAD; ANIMAL; BAGG ALBINO MOUSE; C57BL MOUSE; CENTRAL NERVOUS SYSTEM INFECTION; COMPLICATION; DISEASE MODEL; ENTEROVIRUS D; IMMUNOLOGY; INTERSTITIAL LUNG DISEASE; LD50; NEUROMUSCULAR DISEASE; PASSIVE IMMUNIZATION; PATHOGENICITY; VIROLOGY;

ANIMALS; ANIMALS, NEWBORN; ANTIBODIES, VIRAL; CENTRAL NERVOUS SYSTEM VIRAL DISEASES; DISEASE MODELS, ANIMAL; ENTEROVIRUS D, HUMAN; ENTEROVIRUS INFECTIONS; FEMALE; IMMUNIZATION, PASSIVE; LETHAL DOSE 50; LUNG DISEASES, INTERSTITIAL; MICE; MICE, INBRED BALB C; MICE, INBRED C57BL; MYELITIS; NEUROMUSCULAR DISEASES; VIRAL LOAD; VIRAL TROPISM;

EID: 85057485155     PISSN: 01663542     EISSN: 18729096     Source Type: Journal    
DOI: 10.1016/j.antiviral.2018.11.013     Document Type: Article

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