MRI findings in children with acute flaccid paralysis and cranial nerve dysfunction occurring during the 2014 enterovirus D68 outbreak

American Journal of Neuroradiology

Volumn 36, Issue 2, 2015, Pages 245-250

  Maloney, J A ^a   Mirsky, D M ^a   Messacar, K ^b,c   Dominguez, S R ^b   Schreiner, T ^c   Stence, N V ^a  

^a UNIVERSITY OF COLORADO SCHOOL OF MEDICINE   (United States)

^b Nutrition Obesity Research Center at the University of Colorado   (United States)

^c UNIVERSITY OF COLORADO   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

GADOBENATE DIMEGLUMINE;

ADULT; ANTERIOR HORN CELL; ARTICLE; BRAIN STEM INJURY; CAUDA EQUINA; CENTRAL GRAY MATTER; CLINICAL ARTICLE; CONTRAST ENHANCEMENT; CRANIAL NERVE DYSFUNCTION; ENTEROVIRUS INFECTION; EPIDEMIC; FACIAL NERVE; FEMALE; FLACCID PARALYSIS; HUMAN; LIMB WEAKNESS; MALE; NERVE ROOT; NEUROIMAGING; NEUROLOGIC DISEASE; NUCLEAR MAGNETIC RESONANCE IMAGING; NUCLEAR MAGNETIC RESONANCE SCANNER; PERIPHERAL NEUROPATHY; POLYMERASE CHAIN REACTION; PONTINE TEGMENTUM; RESPIRATORY TRACT DISEASE; SPINAL CORD; SPINAL CORD LESION; BRAIN STEM; CHILD; CRANIAL NERVE DISEASES; ENTEROVIRUS D; ENTEROVIRUS INFECTIONS; PARAPLEGIA; PATHOLOGY; PRESCHOOL CHILD; PROCEDURES; UNITED STATES;

BRAIN STEM; CHILD; CHILD, PRESCHOOL; CRANIAL NERVE DISEASES; DISEASE OUTBREAKS; ENTEROVIRUS D, HUMAN; ENTEROVIRUS INFECTIONS; FEMALE; HUMANS; MAGNETIC RESONANCE IMAGING; MALE; NEUROIMAGING; PARAPLEGIA; UNITED STATES;

EID: 84922855598     PISSN: 01956108     EISSN: 1936959X     Source Type: Journal    
DOI: 10.3174/ajnr.A4188     Document Type: Article

References (37)

1. Committee on the Enteroviruses. Classification of human enteroviruses. Virology 1962;16:501-04
2. Oberste MS, Maher K, Schnurr D, et al. Enterovirus 68 is associated with respiratory illness and shares biological features with both the enteroviruses and the rhinoviruses. J Gen Virol 2004;85(pt 9): 2577-84
3. Centers for Disease Control and Prevention (CDC). Clusters of acute respiratory illness associated with human enterovirus 68: Asia, Europe, and United States, 2008-2010. MMWR Morb Mortal Wkly Rep 2011;60:1301-04
4. Kreuter J, Barnes A. A fatal central nervous system enterovirus 68 infection. Arch Path Lab Med 2011;135:793-96
5. Roux A, Lulu S, Waubrant E, et al. A Polio-like syndrome in California: clinical, radiologic, and serologic evaluation of five children identified by a statewide laboratory over a twelve-month period. Neurology 2014;82(10 suppl):P3.335
6. Midgley C, Jackson MA, Selvarangan R, et al. Severe respiratory illness associated with enterovirus D68: Missouri and Illinois, 2014. MMWR Morb Mortal Wkly Rep 2014;63:798-99
7. CDC Health Alert Network. Acute neurologic illness with focal limb weakness of unknown etiology in children. September 26, 2014. http://www.bt.cdc.gov/han/han00370.asp. Accessed October 6, 2014
8. Pastula DM, Aliabadi N, Haynes AK, et al. Acute neurologic illness of unknown etiology in children: Colorado, August-September 2014. MMWR Morb Mortal Wkly Rep 2014;63;3901-02
9. Wang SM, Liu CC, Tseng HW, et al. Clinical spectrum of enterovirus 71 infection in children in southern Taiwan, with an emphasis on neurological complications. Clin Infect Dis 1999;29:184-90
10. Ooi MH, Wong SC, Lewthwaite P, et al. Clinical features, diagnosis, and management of enterovirus 71. Lancet Neurol 2010;9:1097-105
11. Huang CC, Liu CC, Chang YC, et al. Neurologic complications in children with enterovirus 71 infection. N Engl J Med 1999;341:936-42
12. McMinn P, Stratov I, Nagarajan L, et al. Neurological manifestations of enterovirus 71 infection in children during an outbreak of hand, foot, and mouth disease in Western Australia. Clin Infect Dis 2001;32:236-42
13. McMinn PC. Enterovirus 71 in the Asia-Pacific region: an emerging cause of acute neurological disease in young children. Neurol J Southeast Asia 2003;8:57-63
14. Pérez-Vélez CM, Anderson MS, Robinson CC, et al. Outbreak of neurologic enterovirus type 71 disease: a diagnostic challenge. Clin Infect Dis 2007;45:950-57
15. Chen CY, Chang YC, Huang CC, et al. Acute flaccid paralysis in infants and young children with enterovirus 71 infection: MR imaging findings and clinical correlates. AJNR Am J Neuroradiol 2001;22:200-05
16. Wasserstrom R, Mamourian A, McGary C, et al. Bulbar poliomyelitis: MR findings with pathologic correlation. AJNR Am J Neuroradiol 1992;13:371-73
17. Choudhary A, Sharma S, Sankhyan N, et al. Midbrain and spinal cord magnetic resonance imaging (MRI) changes in poliomyelitis. J Child Neurol 2010;25:497-99
18. Haq A, Wasay M. Magnetic resonance imaging in poliomyelitis. Arch Neurol 2006;63:778
19. Kornreich L, Dagan O, Grunebaum M. MRI in acute poliomyelitis. Neuroradiology 1996;38:371-72
20. Chen F, Li JJ, Liu T, et al. Clinical and neuroimaging features of enterovirus71 related acute flaccid paralysis in patients with handfoot-mouth disease. Asian Pac J Trop Med 2013;6:68-72
21. Lee KY, Lee YJ, Kim TH, et al. Clinico-radiological spectrum in enterovirus 71 infection involving the central nervous system in children. J Clin Neurosci 2014;21:416-20
22. Jang S, Suh S, Ha SM, et al. Enterovirus 71-related encephalomyelitis: usual and unusual magnetic resonance imaging findings. Neuroradiology 2012;54:239-45
23. Shen WC, Chiu HH, Chow KC, et al. MR imaging findings of entero-viral encephalomyelitis: an outbreak in Taiwan. AJNR Am J Neuroradiol 1999;20:1889-95
24. Zeng H, Wen F, Gan Y, et al. MRI and associated clinical characteristics of EV71-induced brainstem encephalitis in children with hand-foot-mouth disease. Neuroradiology 2012;54:623-30
25. Li J, Chen F, Liu T, et al. MRI findings of neurological complications in hand-foot-mouth disease by enterovirus 71 infection. Int J Neurosci 2012;122:338-44
26. Shen WC, Tsai C, Chiu H, et al. MRI of Enterovirus 71 myelitis with monoplegia. Neuroradiology 2000;42:124-27
27. Rao DG, Bateman DE. Hyperintensities of the anterior horn cells on MRI due to poliomyelitis. J Neurol Neurosurg Psychiatry 1997;63:720
28. Malzberg M, Rogg J. Poliomyelitis: hyperintensity of the anterior horn cells on MR images of the spinal cord. AJR Am J Roentgenol 1993;161:863-65
29. França MC Jr, Schmutzler KM, Garibaldi SG, et al. Bilateral substantia nigra involvement in vaccine-associated poliomyelitis. Neurology 2006;66:1597-98
30. Kraushaar G, Patel R, Stoneham GW. West Nile virus: a case report with flaccid paralysis and cervical spinal cord MR imaging findings. AJNR Am J Neuroradiol 2005;26:26-29
31. Hainline ML, Kincaid JC, Carpenter DL, et al. West Nile poliomyelitis in a 7-year-old child. Pediatr Neurol 2008;39:350-54
32. Nguyen C, Haughton V, Ho K, et al. Contrast enhancement in spinal nerve roots: an experimental study. AJNR Am J Neuroradiol 1995;16:265-68
33. Georgy B, Snow R, Hesselink J. MR imaging of spinal nerve roots: techniques, enhancement patterns, and imaging findings. AJR Am J Roentgenol 1996;166:173-79
34. Yikilmaz A, Doganay S, Gumus H, et al. Magnetic resonance imaging of childhood Guillain-Barre syndrome. Childs Nerv Syst 2010;26: 1103-08
35. Krupp LB, Banwell B, Tenembaum S. Consensus definitions proposed for pediatric multiple sclerosis and related disorders. Neurology 2007;68(16 suppl 2):S7-12
36. Andronikou S, Albuquerque-Jonathan G, Wilmshurst J, et al. MRI findings in acute idiopathic transverse myelopathy in children. Pediatr Radiol 2003;33:624-29
37. Wolf VL, Lupo PJ, Lotze TE. Pediatric acute transverse myelitis overview and differential diagnosis. J Child Neurol 2012;27: 1426-36