Virus-induced transcriptional changes in the brain include the differential expression of genes associated with interferon, apoptosis, interleukin 17 receptor A, and glutamate signaling as well as flavivirus-specific upregulation of tRNA synthetases

mBio

Volumn 5, Issue 2, 2014, Pages

  Clarke, Penny ^a   Leser, J Smith ^a   Bowen, Richard A ^b   Tylera, Kenneth L ^a,c  

^a UNIVERSITY OF COLORADO SCHOOL OF MEDICINE   (United States)

^b Department of Environmental and Radiological Health Sciences   (United States)

^c Denver Veterans Administration   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AMINO ACID TRANSFER RNA LIGASE; GLUTAMIC ACID; INTERLEUKIN 17 RECEPTOR; INTERLEUKIN 17 RECEPTOR A; UNCLASSIFIED DRUG;

ADULT; ANIMAL EXPERIMENT; ANIMAL MODEL; APOPTOSIS; ARTICLE; CONTROLLED STUDY; FLAVIVIRUS INFECTION; GENE EXPRESSION; GENETIC TRANSCRIPTION; IMMUNE RESPONSE; JAPANESE ENCEPHALITIS; MALE; MICROARRAY ANALYSIS; MOUSE; NONHUMAN; PRIORITY JOURNAL; REOVIRUS; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION; UPREGULATION; WEST NILE FEVER;

AMINO ACYL-TRNA SYNTHETASES; ANIMALS; APOPTOSIS; BRAIN; ENCEPHALITIS VIRUSES, JAPANESE; GENE EXPRESSION PROFILING; GLUTAMIC ACID; HOST-PATHOGEN INTERACTIONS; INTERFERONS; MAMMALIAN ORTHOREOVIRUS 3; MICE; MICROARRAY ANALYSIS; RECEPTORS, INTERLEUKIN-17; SIGNAL TRANSDUCTION; UP-REGULATION; WEST NILE VIRUS;

EID: 84899712696     PISSN: 21612129     EISSN: 21507511     Source Type: Journal    
DOI: 10.1128/mBio.00902-14     Document Type: Article

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