Unique features in the intracellular transport of typhoid toxin revealed by a genome-wide screen

PLoS Pathogens

Volumn 15, Issue 4, 2019, Pages

  Chang, Shu Jung ^a   Jin, Sheng Chih ^a   Jiao, Xuyao ^a   Galan, Jorge E ^a  

^a YALE UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CYTOLETHAL DISTENDING TOXIN; FLUORESCENT DYE; GUIDE RNA; N ACETYLNEURAMINIC ACID; SALMONELLA ENDOTOXIN; SIALOGLYCOPROTEIN; SNARE PROTEIN; TYPHOID TOXIN; UNCLASSIFIED DRUG; BACTERIAL PROTEIN; BACTERIAL TOXIN; PROTEIN BINDING;

AFFINITY CHROMATOGRAPHY; ARTICLE; BINDING ASSAY; CELL CYCLE; CELL TRACKING; CELLULAR DISTRIBUTION; CONFOCAL MICROSCOPY; CONTROLLED STUDY; CRISPR-CAS9 SYSTEM; DNA SEQUENCE; ENDOPLASMIC RETICULUM ASSOCIATED DEGRADATION; ENDOSOME; ESCHERICHIA COLI; FLOW CYTOMETRY; FLUORESCENCE MICROSCOPY; GENE EDITING; GENE INACTIVATION; GENETIC SCREENING; GOLGI COMPLEX; HUMAN; HUMAN CELL; IMMUNOFLUORESCENCE MICROSCOPY; INTERNALIZATION; INTRACELLULAR TRANSPORT; POLYACRYLAMIDE GEL ELECTROPHORESIS; POLYMERASE CHAIN REACTION; PROTEIN BINDING; SIZE EXCLUSION CHROMATOGRAPHY; TRANSLATION TERMINATION; TYPHOID FEVER; WESTERN BLOTTING; ANTAGONISTS AND INHIBITORS; CRISPR CAS SYSTEM; GENETICS; HELA CELL LINE; INTRACELLULAR SPACE; METABOLISM; MICROBIOLOGY; PATHOGENICITY; SALMONELLA ENTERICA SEROVAR TYPHI; TRANSPORT AT THE CELLULAR LEVEL;

BACTERIAL PROTEINS; BACTERIAL TOXINS; BIOLOGICAL TRANSPORT; CRISPR-CAS SYSTEMS; ENDOPLASMIC RETICULUM-ASSOCIATED DEGRADATION; HELA CELLS; HUMANS; INTRACELLULAR SPACE; PROTEIN BINDING; SALMONELLA TYPHI; TYPHOID FEVER;

EID: 85065051542     PISSN: 15537366     EISSN: 15537374     Source Type: Journal    
DOI: 10.1371/journal.ppat.1007704     Document Type: Article

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