Typhoid fever

New England Journal of Medicine

Volumn 347, Issue 22, 2002, Pages 1770-1782

  Parry, Christopher M ^a   Hein, Tran Tinh ^c   Dougan, Gordon ^b   White, Nicholas J ^a,d   Farrar, Jeremy J ^a,e  

^a UNIVERSITY OF OXFORD   (United Kingdom)

^b IMPERIAL COLLEGE LONDON   (United Kingdom)

^c UNIVERSITY COLLEGE LONDON HOSPITALS   (United Kingdom)

^d MAHIDOL OXFORD TROPICAL MEDICINE RESEARCH UNIT   (Thailand)

^e OXFORD UNIVERSITY CLINICAL RESEARCH UNIT   (Viet Nam)

Author keywords

[No Author keywords available]

Indexed keywords

AMOXICILLIN; AMPICILLIN; ANTIBIOTIC AGENT; AZITHROMYCIN; AZTREONAM; BETA LACTAM ANTIBIOTIC; CEFIXIME; CEFOPERAZONE; CEFOTAXIME; CEFTRIAXONE; CEPHALOSPORIN DERIVATIVE; CHLORAMPHENICOL; COTRIMOXAZOLE; DEXAMETHASONE; HYDROCORTISONE; IMIPENEM; NALIDIXIC ACID; OFLOXACIN; QUINOLINE DERIVED ANTIINFECTIVE AGENT;

ANTIBIOTIC RESISTANCE; ANTIBIOTIC THERAPY; ARTHROPATHY; BACTERIAL GENOME; BONE DISEASE; CLINICAL FEATURE; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; GROWTH RETARDATION; HUMAN; PATHOGENESIS; PRIORITY JOURNAL; RANDOMIZED CONTROLLED TRIAL; REVIEW; SALMONELLA ENTERICA; TENDON RUPTURE; TYPHOID FEVER;

EID: 0037191716     PISSN: 00284793     EISSN: None     Source Type: Journal    
DOI: 10.1056/NEJMra020201     Document Type: Review

References (102)

1. Osler W. The Principles and Practice of Medicine: Designed for the Use of Practitioners and Students of Medicine. 8th Ed. New York: D. Appleton, 1912:1-46.
2. Lin FY, Ho VA, Bay PV, et al. The epidemiology of typhoid fever in the Dong Thap Province, Mekong Delta region of Vietnam. Am J Trop Med Hyg 2000;62:644-8.
3. Sinha A, Sazawal S, Kumar R, et al. Typhoid fever in children aged less than 5 years. Lancet 1999;354:734-7.
4. Ivanoff B. Typhoid fever: Global situation and WHO recommendations. Southeast Asian J Trop Med Public Health 1995;26:Suppl 2:1-6.
5. Woodward TE, Smadel JE, Ley HL Jr, Green R, Mankikar DS. Preliminary report on the beneficial effect of chloromycetin in the treatment of typhoid fever. Ann Intern Med 1948;29:131-4.
6. Mirza SH, Beeching NJ, Hart CA. Multi-drug resistant typhoid: A global problem. J Med Microbiol 1996;44:317-9.
7. Ackers ML, Puhr ND, Tauxe RV, Mintz ED, Laboratory-based surveillance of Salmonella serotype Typhi infections in the United States: Antimicrobial resistance on the rise. JAMA 2000;283:2668-73.
8. Black RE, Cisneros L, Levine MM, Banfi A, Lobos H, Rodriguez H. Case-control study to identify risk factors for paediatric endemic typhoid fever in Santiago, Chile. Bull World Health Organ 1985;63:899-904.
9. Luby SP, Faizan MK, Fisher-Hoch SP, et al. Risk factors for typhoid fever in an endemic setting, Karachi, Pakistan. Epidemiol Infect 1998;120:129-38.
10. Mermin JH, Villar R, Carpenter J, et al. A massive epidemic of multidrug-resistant typhoid fever in Tajikistan associated with consumption of municipal water. J Infect Dis 1999;179:1416-22.
11. Luxemburger C, Chau MC, Mai NL, et al. Risk factors for typhoid fever in the Mekong Delta, southern Viet Nam: A case-control study. Trans R Soc Trop Med Hyg 2001;95:19-23.
12. Gasem MH, Dolmans WM, Keuter MM, Djokomoeljanto RR. Poor food hygiene and housing as risk factors for typhoid fever in Semarang, Indonesia. Trop Med Int Health 2001;6:484-90.
13. Grossman DA, Witham ND, Burr DH, et al. Flagellar serotypes of Salmonella typhi in Indonesia: Relationship among motility, invasiveness, and clinical illness. J Infect Dis 1995;171:212-6.
14. Thong K-L, Bhutta ZA, Pang T. Multidrug-resistant strains of Salmonella enterica serotype typhi are genetically homogenous and coexist with antibiotic-sensitive strains as distinct, independent clones. Int J Infect Dis 2000;4:194-7.
15. Connerton P, Wain J, Hien TT, et al. Epidemic typhoid in Vietnam: Molecular typing of multiple-antibiotic-resistant Salmonella enterica serotype typhi from four outbreaks. J Clin Microbiol 2000;38:895-7.
16. Mirza S, Kariuki S, Mamun KZ, Beeching NJ, Hart CA. Analysis of plasmid and chromosomal DNA of multidrug-resistant Salmonella enterica serovar typhi from Asia. J Clin Microbiol 2000;38:1449-52.
17. Parkhill J, Dougan G, James KD, et al. Complete genome sequence of a multiple drug resistant Salmonella enterica serovar typhi CT18. Nature 2001;413:848-52.
18. McClelland M, Sanderson KE, Spieth J, et al. The complete genome sequence of Salmonella enterica serovar typhimurium LT2. Nature 2001;413:852-6.
19. Blattner FR, Plunkett G III, Bloch CA, et al. The complete genome sequence of Escherichia coli K-12. Science 1997;277:1453-74.
20. Sherburne CK, Lawley TD, Gilmour MW, et al. The complete DNA sequence and analysis of R27, a large IncHI plasmid from Salmonella typhi that is temperature sensitive for transfer. Nucleic Acids Res 2000;28:2177-86.
21. Taylor DE, Chumpitaz JC, Goldstein E Variability of IncHI1 plasmids from Salmonella typhi with special reference to Peruvian plasmids encoding resistance to trimethoprim and other antibiotics. Antimicrob Agents Chemother 1985;28:452-5.
22. Hornick RB, Greisman SE, Woodward TE, DuPont HL, Dawkins AT, Snyder MJ. Typhoid fever: Pathogenesis and immunologic control. N Engl J Med 1970;283:686-91, 739-46.
23. House D, Bishop A, Parry CM, Dougan G, Wain J. Typhoid fever: Pathogenesis and disease. Curr Opin Infect Dis 2001;14:573-8.
24. Butler T, Bell WR, Levin J, Linh NN, Arnold K. Typhoid fever: Studies of coagulation, bacteremia, and endotoxemia. Arch Intern Med 1978;138:407-10.
25. Wain J, Diep TS, Ho VA, et al. Quantitation of bacteria in blood of typhoid fever patients and relationship between counts and clinical features, transmissibility, and antibiotic resistance. J Clin Microbiol 1998;36:1683-7.
26. Wain J, Bay VB, Ha V, et al. Quantitation of bacteria in bone marrow from patients with typhoid fever: Relationship between counts and clinical features. J Clin Microbiol 2001;39:1571-6.
27. Butler T, Ho M, Acharya G, Tiwari M, Gallati H. Interleukin-6, gamma interferon, and tumour necrosis factor receptors in typhoid fever related to outcome of antimicrobial therapy. Antimicrob Agents Chemother 1993;37:2418-21.
28. Keuter M, Dharmana E, Gasem MH, et al. Patterns of proinflammatory cytokines and inhibitors during typhoid fever. J Infect Dis 1994;169:1306-11.
29. Bhutta ZA, Mansoorali N, Hussain R. Plasma cytokines in pediatric typhoidal salmonellosis: Correlation with clinical course and outcome. J Infect 1997;35:253-6.
30. Everest P, Wain J, Roberts M, Rook G, Dougan G. The molecular mechanisms of severe typhoid fever. Trends Microbiol 2001;9:316-20.
31. Gotuzzo E, Frisancho O, Sanchez J, et al. Association between the acquired immunodeficiency syndrome and infection with Salmonella typhi or Salmonella paratyphi in an endemic typhoid area. Arch Intern Med 1991;151:381-2.
32. Crewe-Brown HH, Kartaedt AS, Saunders GL, Khoosal M, McCarthy K. Invasive Salmonella species and HIV infection. In: Proceedings of the 12th World AIDS Conference, Geneva, June 28-July 3, 1998:284. abstract.
33. Dunstan SJ, Stephens HA, Blackwell JM, et al. Genes of the class II and class III major histocompatibility complex are associated with typhoid fever in Vietnam. J Infect Dis 2001;183:261-8.
34. Dunstan SJ, Ho VA, Duc CM, et al. Typhoid fever and genetic polymorphisms at the natural resistance-associated macrophage protein 1. J Infect Dis 2001;183:1156-60.
35. Threlfall EJ, Ward LR, Rowe B, et al. Widespread occurrence of multiple drug-resistant Salmonella typhi in India. Eur J Clin Microbiol Infect Dis 1992;11:990-3.
36. Shanahan PM, Jesudason MV, Thomson CJ, Amyes SG. Molecular analysis of and identification of antibiotic resistance genes in clinical isolates of Salmonella typhi from India. J Clin Microbiol 1998;36:1595-600.
37. Bhutta ZA. Impact of age and drug resistance on mortality in typhoid fever. Arch Dis Child 1996;75:214-7.
38. Shanahan PM, Karamat KA, Thomson CJ, Amyes SGB. Characterization of multi-drug resistant Salmonella typhi from Pakistan. Epidemiol Infect 2000;124:9-16.
39. Hermans PWM, Saha SK, van Leeuwen WJ, Verbrugh HA, van Belkum A, Goessens WHF. Molecular typing of Salmonella typhi strains from Dhaka (Bangladesh) and development of DNA probes identifying plasmidencoded multidrug-resistant isolates. J Clin Microbiol 1996;34:1373-9.
40. Hoa NTT, Diep TS, Wain J, et al. Community-acquired septicaemia in southern Viet Nam: the importance of multidrug-resistant Salmonella typhi. Trans R Soc Trop Med Hyg 1998;92:503-8.
41. Spread of multiresistant Salmonella typhi. Lancet 1990;336:1065-6.
42. Kariuki S, Gilks C, Revathi G, Hart CA. Genotypic analysis of multidrug-resistant Salmonella enterica serovar typhi, Kenya. Emerg Infect Dis 2000;6:649-51.
43. Schwalbe RS, Hoge CW, Morris JG, O'Hanlon PN, Crawford RA, Gilligan PH. In vivo selection for transmissible drug resistance in Salmonella typhi during antimicrobial therapy. Antimicrob Agents Chemother 1990;34:161-3.
44. Sood S, Kapil A, Das B, Jain Y, Kabra SK. Re-emergence of choramphenicol-sensitive Salmonella typhi. Lancet 1999;353:1241-2.
45. Bhutta ZA, Farooqui BJ, Sturm AW. Eradication of a multiple drug resistant Salmonella paratyphi A causing meningitis with ciprofloxacin. J Infect 1992;25:215-9.
46. Saha SK, Talukder SY, Islam M, Saha S. A highly ceftriaxone-resistant Salmonella typhi in Bangladesh. Pediatr Infect Dis J 1999;18:387.
47. Brown JC, Shanahan PM, Jesudason MV, Thomson CJ, Amyes SG. Mutations responsible for reduced susceptibility to 4-quinolones in clinical isolates of multi-resistant Salmonella typhi in India. J Antimicrob Chemother 1996;37:891-900.
48. Wain J, Hoa NT, Chinh NT, et al. Quinolone-resistant Salmonella typhi in Viet Nam: Molecular basis of resistance and clinical response to treatment. Clin Infect Dis 1997;25:1404-10.
49. Threlfall EJ, Ward LR, Skinner JA, Smith HR, Lacey S. Ciprofloxacin-resistant Salmonella typhi and treatment failure. Lancet 1999;353:1590-1.
50. Threlfall EJ, Skinner JA, Ward LR. Detection of decreased in vitro susceptibility to ciprofloxacin in Salmonella enterica serotypes typhi and paratyphi A. J Antimicrob Chemother 2001;48:740-1.
51. Mehta G, Randhawa VS, Mohapatra NP. Intermediate susceptibility to ciprofloxacin in Salmonella typhi strains in India. Eur J Clin Microbiol Infect Dis 2001;20:760-1.
52. Stuart BM, Pullen RL. Typhoid: Clinical analysis of three hundred and sixty cases. Arch Intern Med 1946;78:629-61.
53. Huckstep RL. Typhoid Fever and Other Salmonella Infections. Edinburgh, Scotland: E.&S. Livingstone, 1962.
54. Ferreccio C, Levine MM, Manterola A, et al. Benign bacteremia caused by Salmonella typhi and paratyphi in children younger than 2 years. J Pediatr 1984;106:899-901.
55. Butler T, Islam A, Kabir I, Jones PK. Patterns of morbidity and mortality in typhoid fever dependent on age and gender: A review of 552 hospitalized patients with diarrhea. Rev Infect Dis 1991;13:85-90.
56. Vinh H, Wain J, Vo TN, et al. Two or three days of ofloxacin treatment for uncomplicated multidrug-resistant typhoid fever in children. Antimicrob Agents Chemother 1996;40:958-61.
57. Bitar RE, Tarpley J. Intestinal perforation in typhoid fever: A historical and state-of-the-art review. Rev Infect Dis 1985;7:257-71.
58. van Basten JP, Stockenbrugger R. Typhoid perforation: A review of the literature since 1960. Trop Geogr Med 1994;46:336-9.
59. Hoffman SL, Punjabi NH, Kumala S, et al. Reduction of mortality in chloramphenicol-treated severe typhoid fever by high-dose dexamethasone. N Engl J Med 1984;310:82-8.
60. Punjabi NH, Hoffman SL, Edman DC, et al. Treatment of severe typhoid fever in children with high dose dexamethasone. Pediatr Infect Dis J 1988;7:598-600.
61. Rogerson SJ, Spooner VJ, Smith TA, Richens J. Hydrocortisone in chloramphenicol-treated severe typhoid fever in Papua New Guinea. Trans R Soc Trop Med Hyg 1991;85:113-6.
62. Seoud M, Saade G, Uwaydah M, Azoury R. Typhoid fever in pregnancy. Obstet Gynecol 1988;71:711-4.
63. Reed RP, Klugman KP. Neonatal typhoid fever. Pediatr Infect Dis J 1994;13:774-7.
64. Wain J, Hien TT, Connerton P, et al. Molecular typing of multiple-antibiotic-resistant Salmonella enterica serovar typhi from Vietnam: Application to acute and relapse cases of typhoid fever. J Clin Microbiol 1999;37:2466-72.
65. Levine MM, Black RE, Lanata C. Precise estimation of the numbers of chronic carriers of Salmonella typhi in Santiago, Chile, an endemic area. J Infect Dis 1982;6:724-6.
66. Gilman RH, Terminel M, Levine MM, Hernandez-Mendoza P, Hornick RB. Relative efficacy of blood, urine, rectal swab, bone marrow, and rose-spot cultures for recovery of Salmonella typhi in typhoid fever. Lancet 1975;1:1211-3.
67. Vallenas C, Hernandez H, Kay B, Black R, Gotuzzo E. Efficacy of bone marrow, blood, stool and duodenal contents cultures for bacteriologic confirmation of typhoid fever in children. Pediatr Infect Dis 1985;4:496-8.
68. Hoffman SL, Edman DC, Punjabi NH, et al. Bone marrow aspirate culture superior to streptokinase clot culture and 8 ml 1:10 blood-to-broth ratio blood culture for diagnosis of typhoid fever. Am J Trop Med Hyg 1986;35:836-9.
69. Rubin FA, McWhirter PD, Burr D, et al. Rapid diagnosis of typhoid fever through identification of Salmonella typhi within 18 hours of specimen acquisition by culture of the mononuclear cell-platelet fraction of blood. J Clin Microbiol 1990;28:825-7.
70. Clegg A, Passey M, Omena M, Karigifa KK, Suve N. Re-evaluation of the Widal agglutination test in response to the changing pattern of typhoid fever in the highlands of Papua New Guinea. Acta Trop 1994;57:255-63.
71. Parry CM, Hoa NT, Diep TS, et al. Value of a single-tube Widal test in diagnosis of typhoid fever in Vietnam. J Clin Microbiol 1999;37:2882-6.
72. Lanata CF, Levine MM, Ristori C, et al. Vi serology in detection of chronic Salmonella typhi carriers in an endemic area. Lancet 1983;2:441-3.
73. Bhutta ZA, Mansurali N. Rapid serologic diagnosis of pediatric typhoid fever in an endemic area: A prospective comparative evaluation of two dot-enzyme immunoassays and the Widal test. Am J Trop Med Hyg 1999;61:654-7.
74. House D, Wain J, Ho VA, et al. Serology of typhoid fever in an area of endemicity and its relevance to diagnosis. J Clin Microbiol. 2001;39:1002-7.
75. Song JH, Cho H, Park MY, Na DS, Moon HB, Pai CH. Detection of Salmonella typhi in the blood of patients with typhoid fever by polymerase chain reaction. J Clin Microbiol 1993;31:1439-43.
76. Gotuzzo E, Carrillo C. Quinolones in typhoid fever. Infect Dis Clin Pract 1994;3:345-51.
77. White NJ, Parry CM. The treatment of typhoid fever. Curr Opin Infect Dis 1996;9:298-302.
78. Cao XT, Kneen R, Nguyen TA, Truong DL, White NJ, Parry CM. A comparative study ofofloxacin and cefixime for treatment of typhoid fever in children. Pediatr Infect Dis J 1999;18:245-8.
79. Girgis NI, Butler T, Frenck RW, et al. Azithromycin versus ciprofloxacin for treatment of uncomplicated typhoid fever in a randomized trial in Egypt that includes patients with multidrug resistance. Antimicrob Agents Chemother 1999;43:1441-4.
80. Chinh NT, Parry CM, Ly NT, et al. A randomized controlled comparison ofazithromycin and ofloxacin for treatment of multidrug-resistant and nalidixic acid-resistant enteric fever. Antimicrob Agents Chemother 2000;44:1855-9.
81. Schaad UB, abdus Salam M, Aujard Y, et al. Use of fluoroquinolones in pediatrics: Consensus report of an International Society of Chemotherapy commission. Pediatr Infect Dis J 1995;14:1-9.
82. Bethell DB, Hien TT, Phi LT, et al. Effects on growth of single short courses of fluoroquinolones. Arch Dis Child 1996;74:44-6.
83. Burkhardt JE, Walterspiel JN, Schaad UB. Quinolone arthropathy in animals versus children. Clin Infect Dis 1997;25:1196-204.
84. Doherty CP, Saha SK, Cutting WA. Typhoid fever, ciprofloxacin and growth in young children. Ann Trop Paediatr 2000;20:297-303.
85. Memon IA, Billoo AG, Memon HI. Cefixime: An oral option for the treatment of multidrug-resistant enteric fever in children. South Med J 1997;90:1204-7.
86. Frenck RW Jr, Nakhla I, Sultan Y, et al. Azithromycin versus ceftriaxone for the treatment of uncomplicated typhoid fever in children. Clin Infect Dis 2000;31:1134-8.
87. Butler T, Sridhar CB, Daga MK, et al. Treatment of typhoid fever with azithromycin versus chloramphenicol in a randomized multicentre trial in India. J Antimicrob Chemother 1999;44:243-50.
88. Bhutta ZA. Quinolone-resistant Salmonella paratyphi B meningitis in a newborn: A case report. J Infect 1997;35:308-10.
89. Herzog C. Chemotherapy of typhoid fever: A review of literature. Infection 1976;4:166-73.
90. Leung D, Venkatesan P, Boswell T, Innes JA, Wood MJ. Treatment of typhoid in pregnancy. Lancet 1995;346:648.
91. Loebstein R, Addis A, Ho E, et al. Pregnancy outcome following gestational exposure to fluoroquinolones: A multicenter prospective controlled study. Antimicrob Agents Chemother 1998;42:1336-9.
92. Dutta P, Rasaily R, Saha MR, et al. Ciprofloxacin for treatment of severe typhoid fever in children. Antimicrob Agents Chemother 1993;37:1197-9.
93. Ferreccio C, Morris JG Jr, Valdivieso C, et al. Efficacy ofciprofloxacin in the treatment of chronic typhoid carriers. J Infect Dis 1988;157:1235-9.
94. Bodhidatta L, Taylor DN, Thisyakorn U, Echeverria P. Control of typhoid fever in Bangkok, Thailand, by annual immunization of schoolchildren with parenteral typhoid vaccine. Rev Infect Dis 1987;9:841-5.
95. Engels EA, Falagas ME, Lau J, Bennish ML. Typhoid fever vaccines: A metaanalysis of studies on efficacy and toxicity. BMJ 1998;316:110-6.
96. Wahdan MH, Serie C, Cerisier Y, Sallam S, Germanier R. A controlled field trial of live Salmonella typhi strain Ty 21a oral vaccine against typhoid: Three-year results. J Infect Dis 1982;145:292-5.
97. Levine MM, Ferreccio C, Black RE, Germanier R. Large-scale field trial of Ty21a live oral typhoid vaccine in enteric-coated capsule formulation. Lancet 1987;1:1049-52.
98. Simanjuntak CH, Paleologo FP, Punjabi NH, et al. Oral immunisation against typhoid fever in Indonesia with Ty21a vaccine. Lancet 1991;338:1055-9.
99. Acharya IL, Lowe CU, Thapa R, et al. Prevention of typhoid fever in Nepal with the Vi capsular polysaccharide of Salmonella typhi: A preliminary report. N Engl J Med 1987;317:1101-4.
100. Klugman KP, Gilbertson IT, Koornhof HJ, et al. Protective activity of Vi capsular polysaccharide vaccine against typhoid fever. Lancet 1987;2:1165-9.
101. Lin FYC, Ho VA, Khiem HB, et al. The efficacy of a Salmonella typhi Vi conjugate vaccine in two-to-five-year-old children. N Engl J Med 2001;344:1263-9.
102. Tarr PE, Kuppens L, Jones TC, Ivanoff B, Aparin PG, Heymann DL. Considerations regarding mass vaccination against typhoid fever as an adjunct to sanitation and public health measures: Potential use in an epidemic in Tajikistan. Am J Trop Med Hyg 1999;61:163-70.