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Volumn 9, Issue 10, 2017, Pages

Understanding the mechanism of translocation of adenylate cyclase toxin across biological membranes

Author keywords

Adenylate cyclase; Model membranes; Phospholipase activity; Protein translocation; RTX toxin

Indexed keywords

ADENYLATE CYCLASE TOXIN; CALMODULIN; PHOSPHOLIPASE A; PROTEIN TRANSLOCASE; CYCLIC AMP; INTEGRIN;

EID: 85030166781     PISSN: None     EISSN: 20726651     Source Type: Journal    
DOI: 10.3390/toxins9100295     Document Type: Review
Times cited : (11)

References (62)
  • 1
    • 0025162502 scopus 로고
    • Adenylate Cyclase Toxin is Critical for Colonization and Pertussis Toxin is Critical for Lethal Infection by Bordetella pertussis in Infant Mice
    • Goodwin, M.S.M.; Weiss, A.A.: Adenylate Cyclase Toxin is Critical for Colonization and Pertussis Toxin is Critical for Lethal Infection by Bordetella pertussis in Infant Mice. Infect. Immun. 1990, 58, 3445–3447.
    • (1990) Infect. Immun , vol.58 , pp. 3445-3447
    • Goodwin, M.S.M.1    Weiss, A.A.2
  • 2
    • 0026080402 scopus 로고
    • Pore-Forming Cytolysins of Gram-Negative Bacteria
    • Welch, R.A.: Pore-Forming Cytolysins of Gram-Negative Bacteria. Mol. Microbiol. 1991, 5, 521–528.
    • (1991) Mol. Microbiol , vol.5 , pp. 521-528
    • Welch, R.A.1
  • 3
    • 0024195829 scopus 로고
    • Secretion of Cyclolysin, the Calmodulin-Sensitive Adenylate Cyclase-Haemolysin Bifunctional Protein of Bordetella pertussis
    • Glaser, P.; Sakamoto, H.; Bellalou, J.; Ullmann, A.; Danchin, A. Secretion of Cyclolysin, the Calmodulin-Sensitive Adenylate Cyclase-Haemolysin Bifunctional Protein of Bordetella pertussis. EMBO J. 1988, 7, 3997–4004.
    • (1988) EMBO J , vol.7 , pp. 3997-4004
    • Glaser, P.1    Sakamoto, H.2    Bellalou, J.3    Ullmann, A.4    Danchin, A.5
  • 4
    • 0028519151 scopus 로고
    • Internal Lysine Palmitoylation in Adenylate Cyclase Toxin from Bordetella pertussis
    • Hackett, M.; Guo, L.; Shabanowitz, J.; Hunt, D.F.; Hewlett, E.L. Internal Lysine Palmitoylation in Adenylate Cyclase Toxin from Bordetella pertussis. Science 1994, 266, 433–435.
    • (1994) Science , vol.266 , pp. 433-435
    • Hackett, M.1    Guo, L.2    Shabanowitz, J.3    Hunt, D.F.4    Hewlett, E.L.5
  • 5
    • 0025965870 scopus 로고
    • Bordetella pertussis Adenylate Cyclase Toxin and Hemolytic Activities Require a Second Gene, cyaC, for Activation
    • Barry, E.M.; Weiss, A.A.; Ehrmann, I.E.; Gray, M.C.; Hewlett, E.L.; Goodwin, M.S.M.: Bordetella pertussis Adenylate Cyclase Toxin and Hemolytic Activities Require a Second Gene, cyaC, for Activation. J. Bacteriol. 1991, 173, 720–726.
    • (1991) J. Bacteriol , vol.173 , pp. 720-726
    • Barry, E.M.1    Weiss, A.A.2    Ehrmann, I.E.3    Gray, M.C.4    Hewlett, E.L.5    Goodwin, M.S.M.6
  • 6
    • 0032586774 scopus 로고    scopus 로고
    • Bordetella pertussis Adenylate Cyclase: A Toxin with Multiple Talents
    • Ladant, D.; Ullmann, A. Bordetella pertussis Adenylate Cyclase: A Toxin with Multiple Talents. Trends Microbiol. 1999, 7, 172–176.
    • (1999) Trends Microbiol , vol.7 , pp. 172-176
    • Ladant, D.1    Ullmann, A.2
  • 7
    • 33745224983 scopus 로고    scopus 로고
    • Structural and Functional Characterization of an Essential RTX Subdomain of Bordetella pertussis Adenylate Cyclase Toxin
    • Bauche, C.; Chenal, A.; Knapp, O.; Bodenreider, C.; Benz, R.; Chaffotte, A.; Ladant, D.: Structural and Functional Characterization of an Essential RTX Subdomain of Bordetella pertussis Adenylate Cyclase Toxin. J. Biol. Chem. 2006, 281, 16914–16926.
    • (2006) J. Biol. Chem , vol.281 , pp. 16914-16926
    • Bauche, C.1    Chenal, A.2    Knapp, O.3    Bodenreider, C.4    Benz, R.5    Chaffotte, A.6    Ladant, D.7
  • 8
    • 0028877021 scopus 로고
    • Interaction of Calcium with Bordetella pertussis Adenylate Cyclase Toxin. Characterization of Multiple Calcium-Binding Sites and Calcium-Induced Conformational Changes
    • Rose, T.; Sebo, P.; Bellalou, J.; Ladant, D.: Interaction of Calcium with Bordetella pertussis Adenylate Cyclase Toxin. Characterization of Multiple Calcium-Binding Sites and Calcium-Induced Conformational Changes. J. Biol. Chem. 1995, 270, 26370–26376.
    • (1995) J. Biol. Chem , vol.270 , pp. 26370-26376
    • Rose, T.1    Sebo, P.2    Bellalou, J.3    Ladant, D.4
  • 9
    • 0034467679 scopus 로고    scopus 로고
    • RTX Toxin Structure and Function: A Story of Numerous Anomalies and Few Analogies in Toxin Biology
    • Welch, R.A.: RTX Toxin Structure and Function: A Story of Numerous Anomalies and Few Analogies in Toxin Biology. Curr. Top. Microbiol. Immunol. 2000, 257, 85–111.
    • (2000) Curr. Top. Microbiol. Immunol , vol.257 , pp. 85-111
    • Welch, R.A.1
  • 10
    • 0035821250 scopus 로고    scopus 로고
    • The Adenylate Cyclase Toxin of Bordetella pertussis Binds to Target Cells via the Alpha(M)Beta(2) Integrin (CD11b/CD18)
    • Guermonprez, P.; Khelef, N.; Blouin, E.; Rieu, P.; Ricciardi-Castagnoli, P.; Guiso, N.; Ladant, D.; Leclerc, C. The Adenylate Cyclase Toxin of Bordetella pertussis Binds to Target Cells via the Alpha(M)Beta(2) Integrin (CD11b/CD18). J. Exp. Med. 2001, 193, 1035–1044.
    • (2001) J. Exp. Med , vol.193 , pp. 1035-1044
    • Guermonprez, P.1    Khelef, N.2    Blouin, E.3    Rieu, P.4    Ricciardi-Castagnoli, P.5    Guiso, N.6    Ladant, D.7    Leclerc, C.8
  • 11
    • 0141866842 scopus 로고    scopus 로고
    • Interaction of Bordetella pertussis Adenylate Cyclase with CD11b/CD18. Role of Toxin Acylation and Identification of the Main Integrin Interaction Domain
    • El-Azami-El-Idrissi, M.; Bauche, C.; Loucka, J.; Osicka, R.; Sebo, P.; Ladant, D.; Leclerc, C.: Interaction of Bordetella pertussis Adenylate Cyclase with CD11b/CD18. Role of Toxin Acylation and Identification of the Main Integrin Interaction Domain. J. Biol. Chem. 2003, 278, 38514–38521.
    • (2003) J. Biol. Chem , vol.278 , pp. 38514-38521
    • El-Azami-El-Idrissi, M.1    Bauche, C.2    Loucka, J.3    Osicka, R.4    Sebo, P.5    Ladant, D.6    Leclerc, C.7
  • 13
    • 0019973678 scopus 로고
    • Phagocyte Impotence Caused by an Invasive Bacterial Adenylate Cyclase
    • Confer, D.L.; Eaton, J.W. Phagocyte Impotence Caused by an Invasive Bacterial Adenylate Cyclase. Science 1982, 217, 948–950.
    • (1982) Science , vol.217 , pp. 948-950
    • Confer, D.L.1    Eaton, J.W.2
  • 14
    • 0033956166 scopus 로고    scopus 로고
    • Bordetella pertussis Virulence Factors Affect Phagocytosis by Human Neutrophils
    • Weingart, C.L.; Weiss, A.A. Bordetella pertussis Virulence Factors Affect Phagocytosis by Human Neutrophils. Infect. Immun. 2000, 68, 1735–1739.
    • (2000) Infect. Immun , vol.68 , pp. 1735-1739
    • Weingart, C.L.1    Weiss, A.A.2
  • 15
    • 0025962108 scopus 로고
    • Hemolytic Activity of Adenylate Cyclase Toxin from Bordetella pertussis
    • Ehrmann, I.E.; Gray, M.C.; Gordon, V.M.; Gray, L.S.; Hewlett, E.L. Hemolytic Activity of Adenylate Cyclase Toxin from Bordetella pertussis. FEBS Lett. 1991, 278, 79–83.
    • (1991) FEBS Lett , vol.278 , pp. 79-83
    • Ehrmann, I.E.1    Gray, M.C.2    Gordon, V.M.3    Gray, L.S.4    Hewlett, E.L.5
  • 16
    • 33645050136 scopus 로고    scopus 로고
    • Macrophage Cytotoxicity Produced by Adenylate Cyclase Toxin from Bordetella pertussis: More than just Making Cyclic AMP
    • Hewlett, E.L.; Donato, G.M.; Gray, M.C. Macrophage Cytotoxicity Produced by Adenylate Cyclase Toxin from Bordetella pertussis: More than just Making Cyclic AMP! Mol. Microbiol. 2006, 59, 447–459.
    • (2006) Mol. Microbiol. , vol.59 , pp. 447-459
    • Hewlett, E.L.1    Donato, G.M.2    Gray, M.C.3
  • 17
    • 0028020244 scopus 로고
    • Adenylate Cyclase Toxin (CyaA) of Bordetella pertussis Evidence for the Formation of Small Ion-Permeable Channels and Comparison with HlyA of Escherichia Coli
    • Benz, R.; Maier, E.; Ladant, D.; Ullmann, A.; Sebo, P.: Adenylate Cyclase Toxin (CyaA) of Bordetella pertussis Evidence for the Formation of Small Ion-Permeable Channels and Comparison with HlyA of Escherichia Coli. J. Biol. Chem. 1994, 269, 27231–27239.
    • (1994) J. Biol. Chem , vol.269 , pp. 27231-27239
    • Benz, R.1    Maier, E.2    Ladant, D.3    Ullmann, A.4    Sebo, P.5
  • 18
    • 84956885724 scopus 로고    scopus 로고
    • Bordetella Adenylate Cyclase Toxin is a Unique Ligand of the Integrin Complement Receptor 3
    • Osicka, R.; Osickova, A.; Hasan, S.; Bumba, L.; Cerny, J.; Sebo, P. Bordetella Adenylate Cyclase Toxin is a Unique Ligand of the Integrin Complement Receptor 3. eLife 2015, 4, e10766.
    • (2015) Elife , vol.4
    • Osicka, R.1    Osickova, A.2    Hasan, S.3    Bumba, L.4    Cerny, J.5    Sebo, P.6
  • 21
    • 77949345512 scopus 로고    scopus 로고
    • Pertussis Toxin and Adenylate Cyclase Toxin: Key Virulence Factors of Bordetella pertussis and Cell Biology Tools
    • Carbonetti, N.H.: Pertussis Toxin and Adenylate Cyclase Toxin: Key Virulence Factors of Bordetella pertussis and Cell Biology Tools. Future Microbiol. 2010, 5, 455–469.
    • (2010) Future Microbiol , vol.5 , pp. 455-469
    • Carbonetti, N.H.1
  • 22
    • 34447291354 scopus 로고    scopus 로고
    • Anthrax Toxin: Receptor Binding, Internalization, Pore Formation, and Translocation
    • Young, J.A.T.; Collier, R.J. Anthrax Toxin: Receptor Binding, Internalization, Pore Formation, and Translocation. Annu. Rev. Biochem. 2007, 76, 243–265.
    • (2007) Annu. Rev. Biochem , vol.76 , pp. 243-265
    • Young, J.A.T.1    Collier, R.J.2
  • 23
    • 46449132398 scopus 로고    scopus 로고
    • Suppression of T-Lymphocyte Activation and Chemotaxis by the Adenylate Cyclase Toxin of Bordetella pertussis
    • Paccani, S.R.; Molin, F.D.; Benagiano, M.; Ladant, D.; D’Elios, M.M.; Montecucco, C.; Baldari, C.T. Suppression of T-Lymphocyte Activation and Chemotaxis by the Adenylate Cyclase Toxin of Bordetella pertussis. Infect. Immun. 2008, 76, 2822–2832.
    • (2008) Infect. Immun , vol.76 , pp. 2822-2832
    • Paccani, S.R.1    Molin, F.D.2    Benagiano, M.3    Ladant, D.4    D’Elios, M.M.5    Montecucco, C.6    Baldari, C.T.7
  • 24
    • 0026574666 scopus 로고
    • Distinct Steps in the Penetration of Adenylate Cyclase Toxin of Bordetella pertussis into Sheep Erythrocytes. Translocation of the Toxin Across the Membrane
    • Rogel, A.; Hanski, E. Distinct Steps in the Penetration of Adenylate Cyclase Toxin of Bordetella pertussis into Sheep Erythrocytes. Translocation of the Toxin Across the Membrane. J. Biol. Chem. 1992, 267, 22599–22605.
    • (1992) J. Biol. Chem , vol.267 , pp. 22599-22605
    • Rogel, A.1    Hanski, E.2
  • 25
    • 34250343430 scopus 로고    scopus 로고
    • Segments Crucial for Membrane Translocation and Pore-Forming Activity of Bordetella Adenylate Cyclase Toxin
    • Basler, M.; Knapp, O.; Masin, J.; Fiser, R.; Maier, E.; Benz, R.; Sebo, P.; Osicka, R.: Segments Crucial for Membrane Translocation and Pore-Forming Activity of Bordetella Adenylate Cyclase Toxin. J. Biol. Chem. 2007, 282, 12419–12429.
    • (2007) J. Biol. Chem , vol.282 , pp. 12419-12429
    • Basler, M.1    Knapp, O.2    Masin, J.3    Fiser, R.4    Maier, E.5    Benz, R.6    Sebo, P.7    Osicka, R.8
  • 27
    • 0023932170 scopus 로고
    • Inhibitors of Receptor-Mediated Endocytosis Block the Entry of Bacillus Anthracis Adenylate Cyclase Toxin but Not that of Bordetella pertussis Adenylate Cyclase Toxin
    • Gordon, V.M.; Leppla, S.H.; Hewlett, E.L. Inhibitors of Receptor-Mediated Endocytosis Block the Entry of Bacillus Anthracis Adenylate Cyclase Toxin but Not that of Bordetella pertussis Adenylate Cyclase Toxin. Infect. Immun. 1988, 56, 1066–1069.
    • (1988) Infect. Immun , vol.56 , pp. 1066-1069
    • Gordon, V.M.1    Leppla, S.H.2    Hewlett, E.L.3
  • 29
    • 0342445437 scopus 로고    scopus 로고
    • An Amphipathic a-Helix Including Glutamates 509 and 516 is Crucial for Membrane Translocation of Adenylate Cyclase Toxin and Modulates Formation and Cation Selectivity of its Membrane Channels
    • Osicková, A.; Osicka, R.; Maier, E.; Benz, R.; Šebo, P. An Amphipathic a-Helix Including Glutamates 509 and 516 is Crucial for Membrane Translocation of Adenylate Cyclase Toxin and Modulates Formation and Cation Selectivity of its Membrane Channels. J. Biol. Chem. 1999, 274, 37644–37650.
    • (1999) J. Biol. Chem , vol.274 , pp. 37644-37650
    • Osicková, A.1    Osicka, R.2    Maier, E.3    Benz, R.4    Šebo, P.5
  • 30
    • 84959272523 scopus 로고    scopus 로고
    • Bordetella Adenylate Cyclase Toxin: A Unique Combination of a Pore-Forming Moiety with a Cell-Invading Adenylate Cyclase Enzyme
    • Masin, J.; Osicka, R.; Bumba, L.; Sebo, P. Bordetella Adenylate Cyclase Toxin: A Unique Combination of a Pore-Forming Moiety with a Cell-Invading Adenylate Cyclase Enzyme. Pathog. Dis. 2015, 73, ftv075.
    • (2015) Pathog. Dis , vol.73
    • Masin, J.1    Osicka, R.2    Bumba, L.3    Sebo, P.4
  • 31
    • 84908689374 scopus 로고    scopus 로고
    • Calcium, Acylation, and Molecular Confinement Favor Folding of Bordetella pertussis Adenylate Cyclase Cyaa Toxin
    • Karst, J.C.; Enguéné, V.Y.N.; Cannella, S.E.; Subrini, O.; Hessel, A.; Debard, S.; Ladant, D.; Chenal, A. Calcium, Acylation, and Molecular Confinement Favor Folding of Bordetella pertussis Adenylate Cyclase Cyaa Toxin. J. Biol. Chem. 2014, 289, 30702–30716.
    • (2014) J. Biol. Chem , vol.289 , pp. 30702-30716
    • Karst, J.C.1    Enguéné, V.Y.N.2    Cannella, S.E.3    Subrini, O.4    Hessel, A.5    Debard, S.6    Ladant, D.7    Chenal, A.8
  • 34
    • 0028941589 scopus 로고
    • Membrane Depolarization Prevents Cell Invasion by Bordetella pertussis Adenylate Cyclase Toxin
    • Otero, A.S.; Yi, X.B.; Gray, M.C.; Szabo, G.; Hewlett, E.L. Membrane Depolarization Prevents Cell Invasion by Bordetella pertussis Adenylate Cyclase Toxin. J. Biol. Chem. 1995, 270, 9695–9697.
    • (1995) J. Biol. Chem , vol.270 , pp. 9695-9697
    • Otero, A.S.1    Yi, X.B.2    Gray, M.C.3    Szabo, G.4    Hewlett, E.L.5
  • 35
    • 0032541030 scopus 로고    scopus 로고
    • Distinct Mechanisms for K+ Efflux, Intoxication, and Hemolysis by Bordetella pertussis AC Toxin
    • Gray, M.; Szabo, G.; Otero, A.S.; Gray, L.; Hewlett, E.: Distinct Mechanisms for K+ Efflux, Intoxication, and Hemolysis by Bordetella pertussis AC Toxin. J. Biol. Chem. 1998, 273, 18260–18267.
    • (1998) J. Biol. Chem , vol.273 , pp. 18260-18267
    • Gray, M.1    Szabo, G.2    Otero, A.S.3    Gray, L.4    Hewlett, E.5
  • 36
    • 0034756154 scopus 로고    scopus 로고
    • Characterization of Recombinant Bordetella pertussis Adenylate Cyclase Toxins Carrying Passenger Proteins
    • Gmira, S.; Karimova, G.; Ladant, D. Characterization of Recombinant Bordetella pertussis Adenylate Cyclase Toxins Carrying Passenger Proteins. Res. Microbiol. 2001, 152, 889–900.
    • (2001) Res. Microbiol , vol.152 , pp. 889-900
    • Gmira, S.1    Karimova, G.2    Ladant, D.3
  • 37
    • 84857667121 scopus 로고    scopus 로고
    • Delivery of Large Heterologous Polypeptides Across the Cytoplasmic Membrane of Antigen-Presenting Cells by the Bordetella RTX Hemolysin Moiety Lacking the Adenylyl Cyclase Domain
    • Holubova, J.; Kamanova, J.; Jelinek, J.; Tomala, J.; Masin, J.; Kosova, M.; Stanek, O.; Bumba, L.; Michalek, J.; Kovar, M. et al. Delivery of Large Heterologous Polypeptides Across the Cytoplasmic Membrane of Antigen-Presenting Cells by the Bordetella RTX Hemolysin Moiety Lacking the Adenylyl Cyclase Domain. Infect. Immun. 2012, 80, 1181–1192.
    • (2012) Infect. Immun , vol.80 , pp. 1181-1192
    • Holubova, J.1    Kamanova, J.2    Jelinek, J.3    Tomala, J.4    Masin, J.5    Kosova, M.6    Stanek, O.7    Bumba, L.8    Michalek, J.9    Kovar, M.10
  • 38
    • 84989170938 scopus 로고    scopus 로고
    • Adenylate Cyclase Toxin-Mediated Delivery of the S1 Subunit of Pertussis Toxin into Mammalian Cells
    • Iwaki, M.; Konda, T. Adenylate Cyclase Toxin-Mediated Delivery of the S1 Subunit of Pertussis Toxin into Mammalian Cells. Pathog. Dis. 2016, 74, ftv110.
    • (2016) Pathog. Dis , pp. 74
    • Iwaki, M.1    Konda, T.2
  • 39
    • 34047267309 scopus 로고    scopus 로고
    • Third Activity of Bordetella Adenylate Cyclase (AC) Toxin-Hemolysin. Membrane Translocation of AC Domain Polypeptide Promotes Calcium Influx into CD11b+ Monocytes Independently of the Catalytic and Hemolytic Activities
    • Fiser, R.; Masin, J.; Basler, M.; Krusek, J.; Spulakova, V.; Konopasek, I.; Sebo, P.: Third Activity of Bordetella Adenylate Cyclase (AC) Toxin-Hemolysin. Membrane Translocation of AC Domain Polypeptide Promotes Calcium Influx into CD11b+ Monocytes Independently of the Catalytic and Hemolytic Activities. J. Biol. Chem. 2007, 282, 2808–2820.
    • (2007) J. Biol. Chem , vol.282 , pp. 2808-2820
    • Fiser, R.1    Masin, J.2    Basler, M.3    Krusek, J.4    Spulakova, V.5    Konopasek, I.6    Sebo, P.7
  • 40
    • 77954062233 scopus 로고    scopus 로고
    • Bordetella Adenylate Cyclase Toxin Mobilizes its Beta2 Integrin Receptor into Lipid Rafts to Accomplish Translocation Across Target Cell Membrane in Two Steps
    • Bumba, L.; Masin, J.; Fiser, R.; Sebo, P. Bordetella Adenylate Cyclase Toxin Mobilizes its Beta2 Integrin Receptor into Lipid Rafts to Accomplish Translocation Across Target Cell Membrane in Two Steps. PLoS Pathog. 2010, 6, e1000901.
    • (2010) Plos Pathog , vol.6
    • Bumba, L.1    Masin, J.2    Fiser, R.3    Sebo, P.4
  • 41
    • 0024435652 scopus 로고
    • Adenylate Cyclase Toxins from Bacillus Anthracis and Bordetella pertussis. Different Processes for Interaction with and Entry into Target Cells
    • Gordon, V.M.; Young, W.W., Jr.; Lechler, S.M.; Gray, M.C.; Leppla, S.H.; Hewlett, E.L. Adenylate Cyclase Toxins from Bacillus Anthracis and Bordetella pertussis. Different Processes for Interaction with and Entry into Target Cells. J. Biol. Chem. 1989, 264, 14792–14796.
    • (1989) J. Biol. Chem , vol.264 , pp. 14792-14796
    • Gordon, V.M.1    Young, W.W.2    Lechler, S.M.3    Gray, M.C.4    Leppla, S.H.5    Hewlett, E.L.6
  • 42
    • 0024449602 scopus 로고
    • Bordetella pertussis Adenylate Cyclase: Purification and Characterization of the Toxic form of the Enzyme
    • Rogel, A.; Schultz, J.E.; Brownlie, R.M.; Coote, J.G.; Parton, R.; Hanski, E. Bordetella pertussis Adenylate Cyclase: Purification and Characterization of the Toxic form of the Enzyme. EMBO J. 1989, 8, 2755–2760.
    • (1989) EMBO J , vol.8 , pp. 2755-2760
    • Rogel, A.1    Schultz, J.E.2    Brownlie, R.M.3    Coote, J.G.4    Parton, R.5    Hanski, E.6
  • 43
    • 84857060003 scopus 로고    scopus 로고
    • Role of CD11b/CD18 in the Process of Intoxication by the Adenylate Cyclase Toxin of Bordetella pertussis
    • Eby, J.C.; Gray, M.C.; Mangan, A.R.; Donato, G.M.; Hewlett, E.L. Role of CD11b/CD18 in the Process of Intoxication by the Adenylate Cyclase Toxin of Bordetella pertussis. Infect. Immun. 2012, 80, 850–859.
    • (2012) Infect. Immun , vol.80 , pp. 850-859
    • Eby, J.C.1    Gray, M.C.2    Mangan, A.R.3    Donato, G.M.4    Hewlett, E.L.5
  • 45
    • 25144469471 scopus 로고    scopus 로고
    • Structural Basis for the Interaction of Bordetella pertussis Adenylyl Cyclase Toxin with Calmodulin
    • Guo, Q.; Shen, Y.; Lee, Y.-S.; Gibbs, C.S.; Mrksich, M.; Tang, W.-J. Structural Basis for the Interaction of Bordetella pertussis Adenylyl Cyclase Toxin with Calmodulin. EMBO J. 2005, 24, 3190–3201.
    • (2005) EMBO J , vol.24 , pp. 3190-3201
    • Guo, Q.1    Shen, Y.2    Lee, Y.-S.3    Gibbs, C.S.4    Mrksich, M.5    Tang, W.-J.6
  • 46
    • 75349096080 scopus 로고    scopus 로고
    • Calmodulin-Induced Conformational and Hydrodynamic Changes in the Catalytic Domain of Bordetella pertussis Adenylate Cyclase Toxin
    • Karst, J.C.; Sotomayor Perez, A.C.; Guijarro, J.I.; Raynal, B.; Chenal, A.; Ladant, D. Calmodulin-Induced Conformational and Hydrodynamic Changes in the Catalytic Domain of Bordetella pertussis Adenylate Cyclase Toxin. Biochemistry 2010, 49, 318–328.
    • (2010) Biochemistry , vol.49 , pp. 318-328
    • Karst, J.C.1    Sotomayor Perez, A.C.2    Guijarro, J.I.3    Raynal, B.4    Chenal, A.5    Ladant, D.6
  • 47
    • 84858600993 scopus 로고    scopus 로고
    • Identification of a Region that Assists Membrane Insertion and Translocation of the Catalytic Domain of Bordetella pertussis CyaA Toxin
    • Karst, J.C.; Barker, R.; Devi, U.; Swann, M.J.; Davi, M.; Roser, S.J.; Ladant, D.; Chenal, A.: Identification of a Region that Assists Membrane Insertion and Translocation of the Catalytic Domain of Bordetella pertussis CyaA Toxin. J. Biol. Chem. 2012, 287, 9200–9212.
    • (2012) J. Biol. Chem , vol.287 , pp. 9200-9212
    • Karst, J.C.1    Barker, R.2    Devi, U.3    Swann, M.J.4    Davi, M.5    Roser, S.J.6    Ladant, D.7    Chenal, A.8
  • 48
    • 0034805613 scopus 로고    scopus 로고
    • Translocation-Specific Conformation of Adenylate Cyclase Toxin from Bordetella pertussis Inhibits Toxin-Mediated Hemolysis
    • Gray, M.C.; Lee, S.J.; Gray, L.S.; Zaretzky, F.R.; Otero, A.S.; Szabo, G.; Hewlett, E.L. Translocation-Specific Conformation of Adenylate Cyclase Toxin from Bordetella pertussis Inhibits Toxin-Mediated Hemolysis. J. Bacteriol. 2001, 183, 5904–5910.
    • (2001) J. Bacteriol , vol.183 , pp. 5904-5910
    • Gray, M.C.1    Lee, S.J.2    Gray, L.S.3    Zaretzky, F.R.4    Otero, A.S.5    Szabo, G.6    Hewlett, E.L.7
  • 50
    • 84925156346 scopus 로고    scopus 로고
    • The I-TASSER Suite: Protein Structure and Function Prediction
    • Yang, J.; Yan, R.; Roy, A.; Xu, D.; Poisson, J.; Zhang, Y. The I-TASSER Suite: Protein Structure and Function Prediction. Nat. Methods 2014, 12, 7–8.
    • (2014) Nat. Methods , vol.12 , pp. 7-8
    • Yang, J.1    Yan, R.2    Roy, A.3    Xu, D.4    Poisson, J.5    Zhang, Y.6
  • 51
    • 84984876243 scopus 로고    scopus 로고
    • Negatively Charged Residues of the Segment Linking the Enzyme and Cytolysin Moieties Restrict the Membrane-Permeabilizing Capacity of Adenylate Cyclase Toxin
    • Masin, J.; Osickova, A.; Sukova, A.; Fiser, R.; Halada, P.; Bumba, L.; Linhartova, I.; Osicka, R.; Sebo, P.: Negatively Charged Residues of the Segment Linking the Enzyme and Cytolysin Moieties Restrict the Membrane-Permeabilizing Capacity of Adenylate Cyclase Toxin. Sci. Rep. 2016, 6, 29137.
    • (2016) Sci. Rep , vol.6 , pp. 29137
    • Masin, J.1    Osickova, A.2    Sukova, A.3    Fiser, R.4    Halada, P.5    Bumba, L.6    Linhartova, I.7    Osicka, R.8    Sebo, P.9
  • 52
    • 0032514638 scopus 로고    scopus 로고
    • Charge-Dependent Translocation of Bordetella pertussis Adenylate Cyclase Toxin into Eukaryotic Cells: Implication for the in Vivo Delivery of CD8+ T Cell Epitopes into Antigen-Presenting Cells
    • Karimova, G.; Fayolle, C.; Gmira, S.; Ullmann, A.; Leclerc, C.; Ladant, D. Charge-Dependent Translocation of Bordetella pertussis Adenylate Cyclase Toxin into Eukaryotic Cells: Implication for the in Vivo Delivery of CD8+ T Cell Epitopes into Antigen-Presenting Cells. Proc. Natl. Acad. Sci. USA 1998, 95, 12532–12537.
    • (1998) Proc. Natl. Acad. Sci. USA , vol.95 , pp. 12532-12537
    • Karimova, G.1    Fayolle, C.2    Gmira, S.3    Ullmann, A.4    Leclerc, C.5    Ladant, D.6
  • 54
    • 0028853169 scopus 로고
    • Inhibition of Diabrotica Larval Growth by Patatin, the Lipid Acyl Hydrolase from Potato Tubers
    • Strickland, J.A.; Orr, G.L.; Walsh, T.A. Inhibition of Diabrotica Larval Growth by Patatin, the Lipid Acyl Hydrolase from Potato Tubers. Plant Physiol. 1995, 109, 667–674.
    • (1995) Plant Physiol , vol.109 , pp. 667-674
    • Strickland, J.A.1    Orr, G.L.2    Walsh, T.A.3
  • 55
    • 0016371732 scopus 로고
    • Determination of the Activity of Phospholipases A, C, and D
    • Grossman, S.; Oestreicher, G.; Singer, T.P.: Determination of the Activity of Phospholipases A, C, and D. Methods Biochem. Anal. 1974, 22, 177–204.
    • (1974) Methods Biochem. Anal , vol.22 , pp. 177-204
    • Grossman, S.1    Oestreicher, G.2    Singer, T.P.3
  • 56
    • 84933670464 scopus 로고    scopus 로고
    • More than a Pore: The Interplay of Pore-Forming Proteins and Lipid Membranes
    • Ros, U.; García-Sáez, A.J. More than a Pore: The Interplay of Pore-Forming Proteins and Lipid Membranes. J. Membr. Biol. 2015, 248, 545–561.
    • (2015) J. Membr. Biol , vol.248 , pp. 545-561
    • Ros, U.1    García-Sáez, A.J.2
  • 57
    • 84956589172 scopus 로고    scopus 로고
    • Protein-lipid Interactions and Non-Lamellar Lipidic Structures in Membrane Pore Formation and Membrane Fusion
    • Gilbert, R.J.C.: Protein-lipid Interactions and Non-Lamellar Lipidic Structures in Membrane Pore Formation and Membrane Fusion. Biochim. Biophys. Acta (BBA) Biomembr. 2016, 1858, 487–499.
    • (2016) Biochim. Biophys. Acta (BBA) Biomembr , vol.1858 , pp. 487-499
    • Gilbert, R.J.C.1
  • 58
    • 0037147239 scopus 로고    scopus 로고
    • Bax-Type Apoptotic Proteins Porate Pure Lipid Bilayers through a Mechanism Sensitive to Intrinsic Monolayer Curvature
    • Basañez, G.; Sharpe, J.C.; Galanis, J.; Brandt, T.B.; Hardwick, J.M.; Zimmerberg, J. Bax-Type Apoptotic Proteins Porate Pure Lipid Bilayers through a Mechanism Sensitive to Intrinsic Monolayer Curvature. J. Biol. Chem. 2002, 277, 49360–49365.
    • (2002) J. Biol. Chem , vol.277 , pp. 49360-49365
    • Basañez, G.1    Sharpe, J.C.2    Galanis, J.3    Brandt, T.B.4    Hardwick, J.M.5    Zimmerberg, J.6
  • 60
    • 2942522547 scopus 로고    scopus 로고
    • Membrane Restructuring by Bordetella pertussis Adenylate Cyclase Toxin, a Member of the RTX Toxin Family
    • Martin, C.; Requero, M.A.; Masin, J.; Konopasek, I.; Goni, F.M.; Sebo, P.; Ostolaza, H. Membrane Restructuring by Bordetella pertussis Adenylate Cyclase Toxin, a Member of the RTX Toxin Family. J. Bacteriol. 2004, 186, 3760–3765.
    • (2004) J. Bacteriol , vol.186 , pp. 3760-3765
    • Martin, C.1    Requero, M.A.2    Masin, J.3    Konopasek, I.4    Goni, F.M.5    Sebo, P.6    Ostolaza, H.7
  • 61
    • 0023710642 scopus 로고
    • The ‘Molten Globule’ State is Involved in the Translocation of Proteins Across Membranes?
    • Bychkova, V.E.; Pain, R.H.; Ptitsyn, O.B. The ‘Molten Globule’ State is Involved in the Translocation of Proteins Across Membranes? FEBS Lett. 1988, 238, 231–234.
    • (1988) FEBS Lett , vol.238 , pp. 231-234
    • Bychkova, V.E.1    Pain, R.H.2    Ptitsyn, O.B.3
  • 62
    • 0025212107 scopus 로고
    • Evidence for a Molten Globule State as a General Intermediate in Protein Folding
    • Ptitsyn, O.B.; Pain, R.H.; Semisotnov, G.V.; Zerovnik, E.; Razgulyaev, O.I. Evidence for a Molten Globule State as a General Intermediate in Protein Folding. FEBS Lett. 1990, 262, 20–24.
    • (1990) FEBS Lett , vol.262 , pp. 20-24
    • Ptitsyn, O.B.1    Pain, R.H.2    Semisotnov, G.V.3    Zerovnik, E.4    Razgulyaev, O.I.5


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