Protein O-linked mannose β-1,4-N-acetylglucosaminyltransferase 2 (POMGNT2) is a gatekeeper enzyme for functional glycosylation of α-dystroglycan

Journal of Biological Chemistry

Volumn 292, Issue 6, 2017, Pages 2101-2109

  Halmo, Stephanie M ^a   Singh, Danish ^a   Patel, Sneha ^a   Wang, Shuo ^a   Edlin, Melanie ^a   Boons, Geert Jan ^a   Moremen, Kelley W ^a   Live, David ^a   Wells, Lance ^a  

^a UNIVERSITY OF GEORGIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AMINO ACIDS; BINDING SITES; CATALYSIS; GLYCOSYLATION; PEPTIDES; POLYSACCHARIDES;

ENZYME FUNCTIONS; EXTRACELLULAR MATRIX PROTEIN; GLOBULAR DOMAINS; GLYCAN STRUCTURES; GLYCOPEPTIDES; MUSCULAR DYSTROPHY; PRIMARY AMINO ACID; VERTEBRATE SPECIES;

ENZYMES;

ALPHA DYSTROGLYCAN; MANNOSYLTRANSFERASE; PROTEIN O LINKED MANNOSE BETA 1,2 N ACETYLGLUCOSAMINYLTRANSFERASE 2; PROTEIN O LINKED MANNOSE BETA 1,4 N ACETYLGLUCOSAMINYLTRANSFERASE 2; UNCLASSIFIED DRUG; DYSTROGLYCAN; GLYCOSYLTRANSFERASE; GTDC2 PROTEIN, HUMAN; MANNOSE;

AMINO ACID SEQUENCE; AMINO TERMINAL SEQUENCE; ARTICLE; BINDING AFFINITY; CARBOXY TERMINAL SEQUENCE; CATALYTIC EFFICIENCY; CONSENSUS SEQUENCE; CONSERVED SEQUENCE; CONTROLLED STUDY; ENZYME ACTIVITY; ENZYME SPECIFICITY; HUMAN; IN VITRO STUDY; PROTEIN GLYCOSYLATION; SEQUENCE ALIGNMENT; VERTEBRATE; ENZYME ACTIVE SITE; GLYCOSYLATION; HEK293 CELL LINE; KINETICS; METABOLISM;

CATALYTIC DOMAIN; DYSTROGLYCANS; GLYCOSYLATION; GLYCOSYLTRANSFERASES; HEK293 CELLS; HUMANS; KINETICS; MANNOSE;

EID: 85012050403     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M116.764712     Document Type: Article

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