The NASA twins study: A multidimensional analysis of a year-long human spaceflight

Science

Volumn 364, Issue 6436, 2019, Pages

  Garrett Bakelman, Francine E ^a,b   Darshi, Manjula ^c   Green, Stefan J ^d   Gur, Ruben C ^e   Lin, Ling ^f   Macias, Brandon R ^g   McKenna, Miles J ^h   Meydan, Cem ^a,i   Mishra, Tejaswini ^f   Nasrini, Jad ^e   Piening, Brian D ^f,x   Rizzardi, Lindsay F ^j,y   Sharma, Kumar ^c   Siamwala, Jamila H ^k,z   Taylor, Lynn ^h   Vitaterna, Martha Hotz ^l   Afkarian, Maryam ^m   Afshinnekoo, Ebrahim ^a,i   Ahadi, Sara ^f   Ambati, Aditya ^f   Arya, Maneesh ^g   Bezdan, Daniela ^a,i   Callahan, Colin M ^j   Chen, Songjie ^f   Choi, Augustine M K ^a   Chlipala, George E ^d   Contrepois, Kévin ^f   Covington, Marisa ⁿ   Crucian, Brian E ⁿ   De Vivo, Immaculata ^o   Dinges, David F ^e   Ebert, Douglas J ^g   Feinberg, Jason I ^j   Gandara, Jorge A ^a   George, Kerry A ^g   Goutsias, John ^j   Grills, George S ^a,aa   Hargens, Alan R ^k   Heer, Martina ^p,ab   Hillary, Ryan P ^f   Hoofnagle, Andrew N ^q   Hook, Vivian Y H ^k   Jenkinson, Garrett ^j,ac   Jiang, Peng ^l   Keshavarzian, Ali ^r   Laurie, Steven S ^g   Lee McMullen, B ^f   Lumpkins, Sarah B ^s   MacKay, Matthew ^a   Maienschein Cline, Mark G ^d   Melnick, Ari M ^a   Moore, Tyler M ^e   Nakahira, Kiichi ^a,ad   Patel, Hemal H ^k   Pietrzyk, Robert ^g   Rao, Varsha ^f   Saito, Rintaro ^k,ae   Salins, Denis N ^f   Schilling, Jan M ^k   Sears, Dorothy D ^k   Sheridan, Caroline K ^a   Stenger, Michael B ⁿ   Tryggvadottir, Rakel ^j   Urban, Alexander E ^f   Vaisar, Tomas ^q   Van Espen, Benjamin ^k   Zhang, Jing ^f   Ziegler, Michael G ^k   Zwart, Sara R ^t   Charles, John B ⁿ   Kundrot, Craig E ⁿ   Scott, Graham B I ^u   Bailey, Susan M ^h   Basner, Mathias ^e   Feinberg, Andrew P ^j   Lee, Stuart M C ^g   Mason, Christopher E ^a,i,v,w   Mignot, Emmanuel ^f   Rana, Brinda K ^k   Smith, Scott M ⁿ   Snyder, Michael P ^f   Turek, Fred W ^l,z   more..

^a WEILL CORNELL MEDICAL COLLEGE   (United States)

^b UNIVERSITY OF VIRGINIA   (United States)

^c UNIVERSITY OF TEXAS HEALTH SCIENCE CENTER AT SAN ANTONIO   (United States)

^d UNIVERSITY OF ILLINOIS AT CHICAGO   (United States)

^e UNIVERSITY OF PENNSYLVANIA   (United States)

^f STANFORD UNIVERSITY SCHOOL OF MEDICINE   (United States)

^g KBRWYLE   (United States)

^h Department of Environmental and Radiological Health Sciences   (United States)

ⁱ HRH Prince Alwaleed Bin Talal Bin Abdulaziz Alsaud Institute for Computational Biomedicine   (United States)

^j JOHNS HOPKINS UNIVERSITY   (United States)

^k UNIVERSITY OF CALIFORNIA   (United States)

^l NORTHWESTERN UNIVERSITY   (United States)

^m UNIVERSITY OF CALIFORNIA   (United States)

ⁿ NASA HEADQUARTERS   (United States)

^o HARVARD SCHOOL OF PUBLIC HEALTH   (United States)

^p UNIVERSITY OF BONN   (Germany)

^q UNIVERSITY OF WASHINGTON   (United States)

^r RUSH UNIVERSITY MEDICAL CENTER   (United States)

^s MEI Technologies   (United States)

^t UNIVERSITY OF TEXAS MEDICAL BRANCH   (United States)

^u BAYLOR COLLEGE OF MEDICINE   (United States)

^v FEIL FAMILY BRAIN AND MIND RESEARCH INSTITUTE   (United States)

^w The WorldQuant Initiative for Quantitative Prediction   (United States)

^x PROVIDENCE PORTLAND MEDICAL CENTER   (United States)

^y HUDSONALPHA INSTITUTE FOR BIOTECHNOLOGY   (United States)

^z BROWN UNIVERSITY   (United States)

^aa AUGUSTA UNIVERSITY   (United States)

^ab IU International University of Applied Sciences   (Germany)

^ac MAYO CLINIC   (United States)

^ad NARA MEDICAL UNIVERSITY   (Japan)

^ae KEIO UNIVERSITY   (Japan)

more..

Author keywords

[No Author keywords available]

Indexed keywords

DNA;

BODY MASS; DNA; GENE; GENE EXPRESSION; GENOME; HEALTH IMPACT; HEALTH RISK; METHYLATION; MICROORGANISM; MOLECULAR ANALYSIS; OXIDATIVE STRESS; PHYSIOLOGY;

ARTERIAL WALL THICKNESS; ARTERY DILATATION; ARTICLE; BODY MASS; CAROTID ARTERY; COGNITIVE DEFECT; DNA METHYLATION; ENVIRONMENTAL FACTOR; GENE EXPRESSION; GENOMIC INSTABILITY; HEALTH CARE; HEALTH HAZARD; HUMAN; IMMUNE RESPONSE; INCIDENCE; INFLAMMATION; INTESTINE FLORA; MICROBIOME; OSTEOLYSIS; OXIDATIVE STRESS; PRIORITY JOURNAL; SENSORIMOTOR FUNCTION; SPACE FLIGHT; STEADY STATE; TELOMERE LENGTH; ADAPTATION; ADAPTIVE IMMUNITY; BODY WEIGHT; COSMONAUT; DIAGNOSTIC IMAGING; DNA DAMAGE; GOVERNMENT; MALE; TELOMERE HOMEOSTASIS; TIME FACTOR; TWINS; UNITED STATES;

ADAPTATION, PHYSIOLOGICAL; ADAPTIVE IMMUNITY; ASTRONAUTS; BODY WEIGHT; CAROTID ARTERIES; CAROTID INTIMA-MEDIA THICKNESS; DNA DAMAGE; DNA METHYLATION; GASTROINTESTINAL MICROBIOME; GENOMIC INSTABILITY; HUMANS; MALE; SPACE FLIGHT; TELOMERE HOMEOSTASIS; TIME FACTORS; UNITED STATES; UNITED STATES NATIONAL AERONAUTICS AND SPACE ADMINISTRATION;

EID: 85064686347     PISSN: 00368075     EISSN: 10959203     Source Type: Journal    
DOI: 10.1126/science.aau8650     Document Type: Article

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