-
1
-
-
84874644599
-
KDIGO clinical practice guideline for the evaluation and management of chronic kidney disease
-
Kidney Disease: Improving Global Outcomes (KDIGO) CKD Work Group. KDIGO clinical practice guideline for the evaluation and management of chronic kidney disease. Kidney Int Suppl 3 (2013), 1–150.
-
(2013)
Kidney Int Suppl
, vol.3
, pp. 1-150
-
-
-
2
-
-
84868540565
-
Associations of kidney disease measures with mortality and end-stage renal disease in individuals with and without diabetes: a meta-analysis
-
Fox, CS, Matsushita, K, Woodward, M, et al. Associations of kidney disease measures with mortality and end-stage renal disease in individuals with and without diabetes: a meta-analysis. Lancet 380 (2012), 1662–1673.
-
(2012)
Lancet
, vol.380
, pp. 1662-1673
-
-
Fox, C.S.1
Matsushita, K.2
Woodward, M.3
-
3
-
-
84965028768
-
Unmet need in diabetic nephropathy: failed drugs or trials?
-
de Zeeuw, D, Heerspink, HJ, Unmet need in diabetic nephropathy: failed drugs or trials?. Lancet Diabetes Endocrinol 4 (2016), 638–640.
-
(2016)
Lancet Diabetes Endocrinol
, vol.4
, pp. 638-640
-
-
de Zeeuw, D.1
Heerspink, H.J.2
-
4
-
-
85021282260
-
SGLT2 inhibition: a new era in renoprotective medicine?
-
Muskiet, MHA, Heerspink, HJL, van Raalte, DH, SGLT2 inhibition: a new era in renoprotective medicine?. Lancet Diabetes Endocrinol 5 (2017), 569–571.
-
(2017)
Lancet Diabetes Endocrinol
, vol.5
, pp. 569-571
-
-
Muskiet, M.H.A.1
Heerspink, H.J.L.2
van Raalte, D.H.3
-
5
-
-
84928601182
-
Pleiotropic effects of type 2 diabetes management strategies on renal risk factors
-
Muskiet, MH, Tonneijck, L, Smits, MM, Kramer, MH, Heerspink, HJ, van Raalte, DH, Pleiotropic effects of type 2 diabetes management strategies on renal risk factors. Lancet Diabetes Endocrinol 3 (2015), 367–381.
-
(2015)
Lancet Diabetes Endocrinol
, vol.3
, pp. 367-381
-
-
Muskiet, M.H.1
Tonneijck, L.2
Smits, M.M.3
Kramer, M.H.4
Heerspink, H.J.5
van Raalte, D.H.6
-
6
-
-
84964733198
-
Long-term benefits of intensive glucose control for preventing end-stage kidney disease: ADVANCE-ON
-
Wong, MG, Perkovic, V, Chalmers, J, et al. Long-term benefits of intensive glucose control for preventing end-stage kidney disease: ADVANCE-ON. Diabetes Care 39 (2016), 694–700.
-
(2016)
Diabetes Care
, vol.39
, pp. 694-700
-
-
Wong, M.G.1
Perkovic, V.2
Chalmers, J.3
-
7
-
-
84948577375
-
Overview of data concerning the safe use of antihyperglycemic medications in type 2 diabetes mellitus and chronic kidney disease
-
Roussel, R, Lorraine, J, Rodriguez, A, Salaun-Martin, C, Overview of data concerning the safe use of antihyperglycemic medications in type 2 diabetes mellitus and chronic kidney disease. Adv Ther 32 (2015), 1029–1064.
-
(2015)
Adv Ther
, vol.32
, pp. 1029-1064
-
-
Roussel, R.1
Lorraine, J.2
Rodriguez, A.3
Salaun-Martin, C.4
-
8
-
-
84938208500
-
Metformin use and mortality in patients with advanced chronic kidney disease: national, retrospective, observational, cohort study
-
Hung, SC, Chang, YK, Liu, JS, et al. Metformin use and mortality in patients with advanced chronic kidney disease: national, retrospective, observational, cohort study. Lancet Diabetes Endocrinol 3 (2015), 605–614.
-
(2015)
Lancet Diabetes Endocrinol
, vol.3
, pp. 605-614
-
-
Hung, S.C.1
Chang, Y.K.2
Liu, J.S.3
-
9
-
-
84874125170
-
Pharmacokinetic considerations for the treatment of diabetes in patients with chronic kidney disease
-
Scheen, AJ, Pharmacokinetic considerations for the treatment of diabetes in patients with chronic kidney disease. Expert Opin Drug Metab Toxicol 9 (2013), 529–550.
-
(2013)
Expert Opin Drug Metab Toxicol
, vol.9
, pp. 529-550
-
-
Scheen, A.J.1
-
10
-
-
84919999219
-
Management of hyperglycemia in type 2 diabetes, 2015: a patient-centered approach: update to a position statement of the American Diabetes Association and the European Association for the Study of Diabetes
-
Inzucchi, SE, Bergenstal, RM, Buse, JB, et al. Management of hyperglycemia in type 2 diabetes, 2015: a patient-centered approach: update to a position statement of the American Diabetes Association and the European Association for the Study of Diabetes. Diabetes Care 38 (2015), 140–149.
-
(2015)
Diabetes Care
, vol.38
, pp. 140-149
-
-
Inzucchi, S.E.1
Bergenstal, R.M.2
Buse, J.B.3
-
11
-
-
85044963399
-
Individualizing blood pressure targets for people with diabetes and hypertension: comparing the ADA and the ACC/AHA recommendations
-
de Boer, IH, Bakris, G, Cannon, CP, Individualizing blood pressure targets for people with diabetes and hypertension: comparing the ADA and the ACC/AHA recommendations. JAMA 319 (2018), 1319–1320.
-
(2018)
JAMA
, vol.319
, pp. 1319-1320
-
-
de Boer, I.H.1
Bakris, G.2
Cannon, C.P.3
-
12
-
-
42749099562
-
Angiotensin converting enzyme inhibitors and angiotensin II receptor antagonists for preventing the progression of diabetic kidney disease
-
CD006257.
-
Strippoli, GF, Bonifati, C, Craig, M, Navaneethan, SD, Craig, JC, Angiotensin converting enzyme inhibitors and angiotensin II receptor antagonists for preventing the progression of diabetic kidney disease. Cochrane Database Syst Rev, 4, 2006 CD006257.
-
(2006)
Cochrane Database Syst Rev
, vol.4
-
-
Strippoli, G.F.1
Bonifati, C.2
Craig, M.3
Navaneethan, S.D.4
Craig, J.C.5
-
13
-
-
0035922447
-
Renoprotective effect of the angiotensin-receptor antagonist irbesartan in patients with nephropathy due to type 2 diabetes
-
Lewis, EJ, Hunsicker, LG, Clarke, WR, et al. Renoprotective effect of the angiotensin-receptor antagonist irbesartan in patients with nephropathy due to type 2 diabetes. N Engl J Med 345 (2001), 851–860.
-
(2001)
N Engl J Med
, vol.345
, pp. 851-860
-
-
Lewis, E.J.1
Hunsicker, L.G.2
Clarke, W.R.3
-
14
-
-
0035922441
-
Effects of losartan on renal and cardiovascular outcomes in patients with type 2 diabetes and nephropathy
-
Brenner, BM, Cooper, ME, de Zeeuw, D, et al. Effects of losartan on renal and cardiovascular outcomes in patients with type 2 diabetes and nephropathy. N Engl J Med 345 (2001), 861–869.
-
(2001)
N Engl J Med
, vol.345
, pp. 861-869
-
-
Brenner, B.M.1
Cooper, M.E.2
de Zeeuw, D.3
-
15
-
-
0029902698
-
The hyperfiltration theory: a paradigm shift in nephrology
-
Brenner, BM, Lawler, EV, Mackenzie, HS, The hyperfiltration theory: a paradigm shift in nephrology. Kidney Int 49 (1996), 1774–1777.
-
(1996)
Kidney Int
, vol.49
, pp. 1774-1777
-
-
Brenner, B.M.1
Lawler, E.V.2
Mackenzie, H.S.3
-
16
-
-
85020448574
-
Glomerular hyperfiltration in diabetes: mechanisms, clinical significance, and treatment
-
Tonneijck, L, Muskiet, MH, Smits, MM, et al. Glomerular hyperfiltration in diabetes: mechanisms, clinical significance, and treatment. J Am Soc Nephrol 28 (2017), 1023–1039.
-
(2017)
J Am Soc Nephrol
, vol.28
, pp. 1023-1039
-
-
Tonneijck, L.1
Muskiet, M.H.2
Smits, M.M.3
-
17
-
-
2442680120
-
Proteinuria, a target for renoprotection in patients with type 2 diabetic nephropathy: lessons from RENAAL
-
de Zeeuw, D, Remuzzi, G, Parving, HH, et al. Proteinuria, a target for renoprotection in patients with type 2 diabetic nephropathy: lessons from RENAAL. Kidney Int 65 (2004), 2309–2320.
-
(2004)
Kidney Int
, vol.65
, pp. 2309-2320
-
-
de Zeeuw, D.1
Remuzzi, G.2
Parving, H.H.3
-
18
-
-
84887467090
-
Combined angiotensin inhibition for the treatment of diabetic nephropathy
-
Fried, LF, Emanuele, N, Zhang, JH, et al. Combined angiotensin inhibition for the treatment of diabetic nephropathy. N Engl J Med 369 (2013), 1892–1903.
-
(2013)
N Engl J Med
, vol.369
, pp. 1892-1903
-
-
Fried, L.F.1
Emanuele, N.2
Zhang, J.H.3
-
19
-
-
84869492851
-
Cardiorenal end points in a trial of aliskiren for type 2 diabetes
-
Parving, HH, Brenner, BM, McMurray, JJ, et al. Cardiorenal end points in a trial of aliskiren for type 2 diabetes. N Engl J Med 367 (2012), 2204–2213.
-
(2012)
N Engl J Med
, vol.367
, pp. 2204-2213
-
-
Parving, H.H.1
Brenner, B.M.2
McMurray, J.J.3
-
20
-
-
84863393468
-
Sulodexide fails to demonstrate renoprotection in overt type 2 diabetic nephropathy
-
Packham, DK, Wolfe, R, Reutens, AT, et al. Sulodexide fails to demonstrate renoprotection in overt type 2 diabetic nephropathy. J Am Soc Nephrol 23 (2012), 123–130.
-
(2012)
J Am Soc Nephrol
, vol.23
, pp. 123-130
-
-
Packham, D.K.1
Wolfe, R.2
Reutens, A.T.3
-
21
-
-
77949877308
-
Avosentan for overt diabetic nephropathy
-
Mann, JF, Green, D, Jamerson, K, et al. Avosentan for overt diabetic nephropathy. J Am Soc Nephrol 21 (2010), 527–535.
-
(2010)
J Am Soc Nephrol
, vol.21
, pp. 527-535
-
-
Mann, J.F.1
Green, D.2
Jamerson, K.3
-
22
-
-
84890946148
-
Bardoxolone methyl in type 2 diabetes and stage 4 chronic kidney disease
-
de Zeeuw, D, Akizawa, T, Audhya, P, et al. Bardoxolone methyl in type 2 diabetes and stage 4 chronic kidney disease. N Engl J Med 369 (2013), 2492–2503.
-
(2013)
N Engl J Med
, vol.369
, pp. 2492-2503
-
-
de Zeeuw, D.1
Akizawa, T.2
Audhya, P.3
-
23
-
-
84980320178
-
Sodium glucose cotransporter 2 inhibitors in the treatment of diabetes mellitus: cardiovascular and kidney effects, potential mechanisms, and clinical applications
-
Heerspink, HJ, Perkins, BA, Fitchett, DH, Husain, M, Cherney, DZ, Sodium glucose cotransporter 2 inhibitors in the treatment of diabetes mellitus: cardiovascular and kidney effects, potential mechanisms, and clinical applications. Circulation 134 (2016), 752–772.
-
(2016)
Circulation
, vol.134
, pp. 752-772
-
-
Heerspink, H.J.1
Perkins, B.A.2
Fitchett, D.H.3
Husain, M.4
Cherney, D.Z.5
-
24
-
-
78651349221
-
Biology of human sodium glucose transporters
-
Wright, EM, Loo, DD, Hirayama, BA, Biology of human sodium glucose transporters. Physiol Rev 91 (2011), 733–794.
-
(2011)
Physiol Rev
, vol.91
, pp. 733-794
-
-
Wright, E.M.1
Loo, D.D.2
Hirayama, B.A.3
-
25
-
-
38549182041
-
+-glucose transporter-2 messenger ribonucleic acid expression in kidney of diabetic rats correlates with glycemic levels: involvement of hepatocyte nuclear factor-1α expression and activity
-
+-glucose transporter-2 messenger ribonucleic acid expression in kidney of diabetic rats correlates with glycemic levels: involvement of hepatocyte nuclear factor-1α expression and activity. Endocrinology 149 (2008), 717–724.
-
(2008)
Endocrinology
, vol.149
, pp. 717-724
-
-
Freitas, H.S.1
Anhe, G.F.2
Melo, K.F.3
-
26
-
-
33644688031
-
Glucose transporters in human renal proximal tubular cells isolated from the urine of patients with non-insulin-dependent diabetes
-
Rahmoune, H, Thompson, PW, Ward, JM, Smith, CD, Hong, G, Brown, J, Glucose transporters in human renal proximal tubular cells isolated from the urine of patients with non-insulin-dependent diabetes. Diabetes 54 (2005), 3427–3434.
-
(2005)
Diabetes
, vol.54
, pp. 3427-3434
-
-
Rahmoune, H.1
Thompson, P.W.2
Ward, J.M.3
Smith, C.D.4
Hong, G.5
Brown, J.6
-
27
-
-
85021642011
-
SGLT2 inhibition in the diabetic kidney—from mechanisms to clinical outcome
-
van Bommel, EJ, Muskiet, MH, Tonneijck, L, Kramer, MH, Nieuwdorp, M, van Raalte, DH, SGLT2 inhibition in the diabetic kidney—from mechanisms to clinical outcome. Clin J Am Soc Nephrol 12 (2017), 700–710.
-
(2017)
Clin J Am Soc Nephrol
, vol.12
, pp. 700-710
-
-
van Bommel, E.J.1
Muskiet, M.H.2
Tonneijck, L.3
Kramer, M.H.4
Nieuwdorp, M.5
van Raalte, D.H.6
-
28
-
-
84969915634
-
Efficacy and safety of sodium-glucose co-transporter-2 inhibitors in type 2 diabetes mellitus: systematic review and network meta-analysis
-
Zaccardi, F, Webb, DR, Htike, ZZ, Youssef, D, Khunti, K, Davies, MJ, Efficacy and safety of sodium-glucose co-transporter-2 inhibitors in type 2 diabetes mellitus: systematic review and network meta-analysis. Diabetes Obes Metab 18 (2016), 783–794.
-
(2016)
Diabetes Obes Metab
, vol.18
, pp. 783-794
-
-
Zaccardi, F.1
Webb, D.R.2
Htike, Z.Z.3
Youssef, D.4
Khunti, K.5
Davies, M.J.6
-
29
-
-
85046816925
-
Renoprotective effects of sodium-glucose cotransporter-2 inhibitors
-
Heerspink, HJL, Kosiborod, M, Inzucchi, SE, Cherney, DZI, Renoprotective effects of sodium-glucose cotransporter-2 inhibitors. Kidney Int 94 (2018), 26–39.
-
(2018)
Kidney Int
, vol.94
, pp. 26-39
-
-
Heerspink, H.J.L.1
Kosiborod, M.2
Inzucchi, S.E.3
Cherney, D.Z.I.4
-
30
-
-
84864371186
-
Weight loss induced by chronic dapagliflozin treatment is attenuated by compensatory hyperphagia in diet-induced obese (DIO) rats
-
Devenny, JJ, Godonis, HE, Harvey, SJ, Rooney, S, Cullen, MJ, Pelleymounter, MA, Weight loss induced by chronic dapagliflozin treatment is attenuated by compensatory hyperphagia in diet-induced obese (DIO) rats. Obesity (Silver Spring) 20 (2012), 1645–1652.
-
(2012)
Obesity (Silver Spring)
, vol.20
, pp. 1645-1652
-
-
Devenny, J.J.1
Godonis, H.E.2
Harvey, S.J.3
Rooney, S.4
Cullen, M.J.5
Pelleymounter, M.A.6
-
31
-
-
85036535429
-
Increased sugar intake as a form of compensatory hyperphagia in patients with type 2 diabetes under dapagliflozin treatment
-
Horie, I, Abiru, N, Hongo, R, et al. Increased sugar intake as a form of compensatory hyperphagia in patients with type 2 diabetes under dapagliflozin treatment. Diabetes Res Clin Pract 135 (2018), 178–184.
-
(2018)
Diabetes Res Clin Pract
, vol.135
, pp. 178-184
-
-
Horie, I.1
Abiru, N.2
Hongo, R.3
-
32
-
-
67349180574
-
Dapagliflozin, a novel SGLT2 inhibitor, induces dose-dependent glucosuria in healthy subjects
-
Komoroski, B, Vachharajani, N, Boulton, D, et al. Dapagliflozin, a novel SGLT2 inhibitor, induces dose-dependent glucosuria in healthy subjects. Clin Pharmacol Ther 85 (2009), 520–526.
-
(2009)
Clin Pharmacol Ther
, vol.85
, pp. 520-526
-
-
Komoroski, B.1
Vachharajani, N.2
Boulton, D.3
-
33
-
-
84959460390
-
Blood pressure and glycaemic effects of dapagliflozin versus placebo in patients with type 2 diabetes on combination antihypertensive therapy: a randomised, double-blind, placebo-controlled, phase 3 study
-
Weber, MA, Mansfield, TA, Cain, VA, Iqbal, N, Parikh, S, Ptaszynska, A, Blood pressure and glycaemic effects of dapagliflozin versus placebo in patients with type 2 diabetes on combination antihypertensive therapy: a randomised, double-blind, placebo-controlled, phase 3 study. Lancet Diabetes Endocrinol 4 (2016), 211–220.
-
(2016)
Lancet Diabetes Endocrinol
, vol.4
, pp. 211-220
-
-
Weber, M.A.1
Mansfield, T.A.2
Cain, V.A.3
Iqbal, N.4
Parikh, S.5
Ptaszynska, A.6
-
34
-
-
84959553475
-
Antihypertensive effects of SGLT2 inhibitors in type 2 diabetes
-
Muskiet, MHA, van Bommel, EJ, van Raalte, DH, Antihypertensive effects of SGLT2 inhibitors in type 2 diabetes. Lancet Diabetes Endocrinol 4 (2016), 188–189.
-
(2016)
Lancet Diabetes Endocrinol
, vol.4
, pp. 188-189
-
-
Muskiet, M.H.A.1
van Bommel, E.J.2
van Raalte, D.H.3
-
35
-
-
84944800184
-
Empagliflozin, cardiovascular outcomes, and mortality in type 2 diabetes
-
Zinman, B, Wanner, C, Lachin, JM, et al. Empagliflozin, cardiovascular outcomes, and mortality in type 2 diabetes. N Engl J Med 373 (2015), 2117–2128.
-
(2015)
N Engl J Med
, vol.373
, pp. 2117-2128
-
-
Zinman, B.1
Wanner, C.2
Lachin, J.M.3
-
36
-
-
85034766786
-
Canagliflozin and cardiovascular and renal events in type 2 diabetes
-
Neal, B, Perkovic, V, Mahaffey, KW, et al. Canagliflozin and cardiovascular and renal events in type 2 diabetes. N Engl J Med 377 (2017), 644–657.
-
(2017)
N Engl J Med
, vol.377
, pp. 644-657
-
-
Neal, B.1
Perkovic, V.2
Mahaffey, K.W.3
-
37
-
-
85048935795
-
Canagliflozin and renal outcomes in type 2 diabetes: results from the CANVAS Program randomised clinical trials
-
Perkovic, V, Zeeuw, D, Mahaffey, KW, et al. Canagliflozin and renal outcomes in type 2 diabetes: results from the CANVAS Program randomised clinical trials. Lancet Diabetes Endocrinol 6 (2018), 691–704.
-
(2018)
Lancet Diabetes Endocrinol
, vol.6
, pp. 691-704
-
-
Perkovic, V.1
Zeeuw, D.2
Mahaffey, K.W.3
-
38
-
-
85056862214
-
Dapagliflozin and cardiovascular outcomes in type 2 diabetes
-
published online, 1056/NEJMoa1812389
-
Wiviott, DS, Raz, I, Bonaca, MP, et al. Dapagliflozin and cardiovascular outcomes in type 2 diabetes. N Engl J Med, 2018 published online DOI:1056/NEJMoa1812389.
-
(2018)
N Engl J Med
-
-
Wiviott, D.S.1
Raz, I.2
Bonaca, M.P.3
-
39
-
-
84979895487
-
Empagliflozin and progression of kidney disease in type 2 diabetes
-
Wanner, C, Inzucchi, SE, Lachin, JM, et al. Empagliflozin and progression of kidney disease in type 2 diabetes. N Engl J Med 375 (2016), 323–334.
-
(2016)
N Engl J Med
, vol.375
, pp. 323-334
-
-
Wanner, C.1
Inzucchi, S.E.2
Lachin, J.M.3
-
40
-
-
85021254729
-
Effects of empagliflozin on the urinary albumin-to-creatinine ratio in patients with type 2 diabetes and established cardiovascular disease: an exploratory analysis from the EMPA-REG OUTCOME randomised, placebo-controlled trial
-
Cherney, DZI, Zinman, B, Inzucchi, SE, et al. Effects of empagliflozin on the urinary albumin-to-creatinine ratio in patients with type 2 diabetes and established cardiovascular disease: an exploratory analysis from the EMPA-REG OUTCOME randomised, placebo-controlled trial. Lancet Diabetes Endocrinol 5 (2017), 610–621.
-
(2017)
Lancet Diabetes Endocrinol
, vol.5
, pp. 610-621
-
-
Cherney, D.Z.I.1
Zinman, B.2
Inzucchi, S.E.3
-
41
-
-
85053770094
-
Cardiovascular and renal outcomes with canagliflozin according to baseline kidney function: data from the CANVAS Program
-
published online June 25.
-
Neuen, BL, Ohkuma, T, Neal, B, et al. Cardiovascular and renal outcomes with canagliflozin according to baseline kidney function: data from the CANVAS Program. Circulation, 2018 published online June 25. DOI:10.1161/CIRCULATIONAHA.118.035901.
-
(2018)
Circulation
-
-
Neuen, B.L.1
Ohkuma, T.2
Neal, B.3
-
42
-
-
85048928314
-
Renal outcomes in CVOTs: keep calm and carry on
-
Muskiet, MHA, van Baar, MJB, Scholtes, RA, van Raalte, DH, Renal outcomes in CVOTs: keep calm and carry on. Lancet Diabetes Endocrinol 6 (2018), 674–676.
-
(2018)
Lancet Diabetes Endocrinol
, vol.6
, pp. 674-676
-
-
Muskiet, M.H.A.1
van Baar, M.J.B.2
Scholtes, R.A.3
van Raalte, D.H.4
-
44
-
-
84893214045
-
Renal hemodynamic effect of sodium-glucose cotransporter 2 inhibition in patients with type 1 diabetes mellitus
-
Cherney, DZ, Perkins, BA, Soleymanlou, N, et al. Renal hemodynamic effect of sodium-glucose cotransporter 2 inhibition in patients with type 1 diabetes mellitus. Circulation 129 (2014), 587–597.
-
(2014)
Circulation
, vol.129
, pp. 587-597
-
-
Cherney, D.Z.1
Perkins, B.A.2
Soleymanlou, N.3
-
45
-
-
85055838159
-
Empagliflozin and kidney function decline in patients with type 2 diabetes: A slope analysis from the EMPA REG OUTCOME trial
-
Wanner, C, Heerspink, HJL, Zinman, B, et al. Empagliflozin and kidney function decline in patients with type 2 diabetes: A slope analysis from the EMPA REG OUTCOME trial. J Am soc Nephrol 29 (2018), 2755–2769.
-
(2018)
J Am soc Nephrol
, vol.29
, pp. 2755-2769
-
-
Wanner, C.1
Heerspink, H.J.L.2
Zinman, B.3
-
46
-
-
79960407033
-
An acute fall in estimated glomerular filtration rate during treatment with losartan predicts a slower decrease in long-term renal function
-
Holtkamp, FA, de Zeeuw, D, Thomas, MC, et al. An acute fall in estimated glomerular filtration rate during treatment with losartan predicts a slower decrease in long-term renal function. Kidney Int 80 (2011), 282–287.
-
(2011)
Kidney Int
, vol.80
, pp. 282-287
-
-
Holtkamp, F.A.1
de Zeeuw, D.2
Thomas, M.C.3
-
47
-
-
84975840750
-
Can a shift in fuel energetics explain the beneficial cardiorenal outcomes in the EMPA-REG OUTCOME study? A unifying hypothesis
-
Mudaliar, S, Alloju, S, Henry, RR, Can a shift in fuel energetics explain the beneficial cardiorenal outcomes in the EMPA-REG OUTCOME study? A unifying hypothesis. Diabetes Care 39 (2016), 1115–1122.
-
(2016)
Diabetes Care
, vol.39
, pp. 1115-1122
-
-
Mudaliar, S.1
Alloju, S.2
Henry, R.R.3
-
48
-
-
85030447466
-
GLP-1 and the kidney: from physiology to pharmacology and outcomes in diabetes
-
Muskiet, MHA, Tonneijck, L, Smits, MM, et al. GLP-1 and the kidney: from physiology to pharmacology and outcomes in diabetes. Nat Rev Nephrol 13 (2017), 605–628.
-
(2017)
Nat Rev Nephrol
, vol.13
, pp. 605-628
-
-
Muskiet, M.H.A.1
Tonneijck, L.2
Smits, M.M.3
-
49
-
-
84976260652
-
Pharmacology and therapeutic implications of current drugs for type 2 diabetes mellitus
-
Tahrani, AA, Barnett, AH, Bailey, CJ, Pharmacology and therapeutic implications of current drugs for type 2 diabetes mellitus. Nat Rev Endocrinol 12 (2016), 566–592.
-
(2016)
Nat Rev Endocrinol
, vol.12
, pp. 566-592
-
-
Tahrani, A.A.1
Barnett, A.H.2
Bailey, C.J.3
-
50
-
-
78649686908
-
Dipeptidyl peptidase-4 inhibitors in the treatment of type 2 diabetes: a comparative review
-
Deacon, CF, Dipeptidyl peptidase-4 inhibitors in the treatment of type 2 diabetes: a comparative review. Diabetes Obes Metab 13 (2011), 7–18.
-
(2011)
Diabetes Obes Metab
, vol.13
, pp. 7-18
-
-
Deacon, C.F.1
-
51
-
-
85064258816
-
Summary of product characteristics—dapagliflozin
-
(Accessed 21 August 2018)
-
Summary of product characteristics—dapagliflozin. http://www.ema.europa.eu/docs/en_GB/document_library/EPAR_-_Product_Information/human/002322/WC500136026.pdf. (Accessed 21 August 2018)
-
-
-
-
52
-
-
85064258816
-
Summary of product characteristics—empagliflozin
-
(Accessed 21 August 2018)
-
Summary of product characteristics—empagliflozin. http://www.ema.europa.eu/docs/en_GB/document_library/EPAR_-_Product_Information/human/002677/WC500168592.pdf. (Accessed 21 August 2018)
-
-
-
-
53
-
-
85064258816
-
Summary of product characteristics—canagliflozin
-
(Accessed 21 August 2018)
-
Summary of product characteristics—canagliflozin. http://www.ema.europa.eu/docs/en_GB/document_library/EPAR_-_Product_Information/human/002649/WC500156456.pdf. (Accessed 21 August 2018)
-
-
-
-
54
-
-
85021694438
-
Differential effects of dapagliflozin on cardiovascular risk factors at varying degrees of renal function
-
Petrykiv, S, Sjostrom, CD, Greasley, PJ, Xu, J, Persson, F, Heerspink, HJL, Differential effects of dapagliflozin on cardiovascular risk factors at varying degrees of renal function. Clin J Am Soc Nephrol 12 (2017), 751–759.
-
(2017)
Clin J Am Soc Nephrol
, vol.12
, pp. 751-759
-
-
Petrykiv, S.1
Sjostrom, C.D.2
Greasley, P.J.3
Xu, J.4
Persson, F.5
Heerspink, H.J.L.6
-
56
-
-
85042792101
-
Empagliflozin and clinical outcomes in patients with type 2 diabetes mellitus, established cardiovascular disease, and chronic kidney disease
-
Wanner, C, Lachin, JM, Inzucchi, SE, et al. Empagliflozin and clinical outcomes in patients with type 2 diabetes mellitus, established cardiovascular disease, and chronic kidney disease. Circulation 137 (2018), 119–129.
-
(2018)
Circulation
, vol.137
, pp. 119-129
-
-
Wanner, C.1
Lachin, J.M.2
Inzucchi, S.E.3
-
57
-
-
85021849793
-
Canagliflozin slows progression of renal function decline independently of glycemic effects
-
Heerspink, HJ, Desai, M, Jardine, M, Balis, D, Meininger, G, Perkovic, V, Canagliflozin slows progression of renal function decline independently of glycemic effects. J Am Soc Nephrol 28 (2017), 368–375.
-
(2017)
J Am Soc Nephrol
, vol.28
, pp. 368-375
-
-
Heerspink, H.J.1
Desai, M.2
Jardine, M.3
Balis, D.4
Meininger, G.5
Perkovic, V.6
-
58
-
-
85038113623
-
The Canagliflozin and Renal Endpoints in Diabetes with Established Nephropathy Clinical Evaluation (CREDENCE) study rationale, design, and baseline characteristics
-
Jardine, MJ, Mahaffey, KW, Neal, B, et al. The Canagliflozin and Renal Endpoints in Diabetes with Established Nephropathy Clinical Evaluation (CREDENCE) study rationale, design, and baseline characteristics. Am J Nephrol 46 (2017), 462–472.
-
(2017)
Am J Nephrol
, vol.46
, pp. 462-472
-
-
Jardine, M.J.1
Mahaffey, K.W.2
Neal, B.3
-
59
-
-
85044732899
-
New diabetes therapies and diabetic kidney disease progression: the role of SGLT-2 inhibitors
-
Dekkers, CCJ, Gansevoort, RT, Heerspink, HJL, New diabetes therapies and diabetic kidney disease progression: the role of SGLT-2 inhibitors. Curr Diab Rep, 18, 2018, 27.
-
(2018)
Curr Diab Rep
, vol.18
, pp. 27
-
-
Dekkers, C.C.J.1
Gansevoort, R.T.2
Heerspink, H.J.L.3
-
60
-
-
85059622269
-
Boehringer Ingelheim and Lilly announce an academic collaboration with University of Oxford to investigate the effects of empagliflozin in people with chronic kidney disease
-
(Accessed 21 August 2018)
-
Boehringer Ingelheim and Lilly announce an academic collaboration with University of Oxford to investigate the effects of empagliflozin in people with chronic kidney disease. https://www.boehringer-ingelheim.com/EMPA-KIDNEY. (Accessed 21 August 2018)
-
-
-
-
61
-
-
85044154182
-
Mechanisms of action and therapeutic application of glucagon-like peptide-1
-
Drucker, DJ, Mechanisms of action and therapeutic application of glucagon-like peptide-1. Cell Metab 27 (2018), 740–756.
-
(2018)
Cell Metab
, vol.27
, pp. 740-756
-
-
Drucker, D.J.1
-
62
-
-
84957842766
-
Gastrointestinal actions of glucagon-like peptide-1-based therapies: glycaemic control beyond the pancreas
-
Smits, MM, Tonneijck, L, Muskiet, MH, Kramer, MH, Cahen, DL, van Raalte, DH, Gastrointestinal actions of glucagon-like peptide-1-based therapies: glycaemic control beyond the pancreas. Diabetes Obes Metab 18 (2016), 224–235.
-
(2016)
Diabetes Obes Metab
, vol.18
, pp. 224-235
-
-
Smits, M.M.1
Tonneijck, L.2
Muskiet, M.H.3
Kramer, M.H.4
Cahen, D.L.5
van Raalte, D.H.6
-
63
-
-
84957665720
-
The incretin effect in healthy individuals and those with type 2 diabetes: physiology, pathophysiology, and response to therapeutic interventions
-
Nauck, MA, Meier, JJ, The incretin effect in healthy individuals and those with type 2 diabetes: physiology, pathophysiology, and response to therapeutic interventions. Lancet Diabetes Endocrinol 4 (2016), 525–536.
-
(2016)
Lancet Diabetes Endocrinol
, vol.4
, pp. 525-536
-
-
Nauck, M.A.1
Meier, J.J.2
-
64
-
-
64649104158
-
From the triumvirate to the ominous octet: a new paradigm for the treatment of type 2 diabetes mellitus
-
Defronzo, RA, From the triumvirate to the ominous octet: a new paradigm for the treatment of type 2 diabetes mellitus. Diabetes 58 (2009), 773–795.
-
(2009)
Diabetes
, vol.58
, pp. 773-795
-
-
Defronzo, R.A.1
-
65
-
-
0031724691
-
Influence of glucagon-like peptide 1 on fasting glycemia in type 2 diabetic patients treated with insulin after sulfonylurea secondary failure
-
Nauck, MA, Sauerwald, A, Ritzel, R, Holst, JJ, Schmiegel, W, Influence of glucagon-like peptide 1 on fasting glycemia in type 2 diabetic patients treated with insulin after sulfonylurea secondary failure. Diabetes Care 21 (1998), 1925–1931.
-
(1998)
Diabetes Care
, vol.21
, pp. 1925-1931
-
-
Nauck, M.A.1
Sauerwald, A.2
Ritzel, R.3
Holst, J.J.4
Schmiegel, W.5
-
66
-
-
84922380651
-
Effects of glucagon-like peptide-1 receptor agonists on weight loss in patients with type 2 diabetes: a systematic review and network meta-analysis
-
Sun, F, Chai, S, Li, L, et al. Effects of glucagon-like peptide-1 receptor agonists on weight loss in patients with type 2 diabetes: a systematic review and network meta-analysis. J Diabetes Res, 2015, 2015, 157201.
-
(2015)
J Diabetes Res
, vol.2015
, pp. 157201
-
-
Sun, F.1
Chai, S.2
Li, L.3
-
67
-
-
77954380946
-
Twelve weeks treatment with the DPP-4 inhibitor, sitagliptin, prevent s degradation of peptide YY and improves glucose and non-glucose induced insulin secretion in patients with type 2 diabetes mellitus
-
Aaboe, K, Knop, FK, Vilsboll, T, et al. Twelve weeks treatment with the DPP-4 inhibitor, sitagliptin, prevent s degradation of peptide YY and improves glucose and non-glucose induced insulin secretion in patients with type 2 diabetes mellitus. Diabetes Obes Metab 12 (2010), 323–333.
-
(2010)
Diabetes Obes Metab
, vol.12
, pp. 323-333
-
-
Aaboe, K.1
Knop, F.K.2
Vilsboll, T.3
-
68
-
-
84943197778
-
Impact of GLP-1 receptor agonists on blood pressure, heart rate and hypertension among patients with type 2 diabetes: a systematic review and network meta-analysis
-
Sun, F, Wu, S, Guo, S, et al. Impact of GLP-1 receptor agonists on blood pressure, heart rate and hypertension among patients with type 2 diabetes: a systematic review and network meta-analysis. Diabetes Res Clin Pract 110 (2015), 26–37.
-
(2015)
Diabetes Res Clin Pract
, vol.110
, pp. 26-37
-
-
Sun, F.1
Wu, S.2
Guo, S.3
-
69
-
-
84895072279
-
The gut-renal axis: do incretin-based agents confer renoprotection in diabetes?
-
Muskiet, MH, Smits, MM, Morsink, LM, Diamant, M, The gut-renal axis: do incretin-based agents confer renoprotection in diabetes?. Nat Rev Nephrol 10 (2014), 88–103.
-
(2014)
Nat Rev Nephrol
, vol.10
, pp. 88-103
-
-
Muskiet, M.H.1
Smits, M.M.2
Morsink, L.M.3
Diamant, M.4
-
70
-
-
84876266256
-
Glucagon-like peptide-1 (GLP-1): effect on kidney hemodynamics and renin-angiotensin-aldosterone system in healthy men
-
Skov, J, Dejgaard, A, Frokiaer, J, et al. Glucagon-like peptide-1 (GLP-1): effect on kidney hemodynamics and renin-angiotensin-aldosterone system in healthy men. J Clin Endocrinol Metab 98 (2013), E664–E671.
-
(2013)
J Clin Endocrinol Metab
, vol.98
, pp. E664-E671
-
-
Skov, J.1
Dejgaard, A.2
Frokiaer, J.3
-
71
-
-
84957063828
-
Acute renal haemodynamic effects of glucagon-like peptide-1 receptor agonist exenatide in healthy overweight men
-
Muskiet, MH, Tonneijck, L, Smits, MM, et al. Acute renal haemodynamic effects of glucagon-like peptide-1 receptor agonist exenatide in healthy overweight men. Diabetes Obes Metab 18 (2016), 178–185.
-
(2016)
Diabetes Obes Metab
, vol.18
, pp. 178-185
-
-
Muskiet, M.H.1
Tonneijck, L.2
Smits, M.M.3
-
72
-
-
84995609063
-
Short-term effects of liraglutide on kidney function and vasoactive hormones in type 2 diabetes: a randomized clinical trial
-
Skov, J, Pedersen, M, Holst, JJ, et al. Short-term effects of liraglutide on kidney function and vasoactive hormones in type 2 diabetes: a randomized clinical trial. Diabetes Obes Metab 18 (2016), 581–589.
-
(2016)
Diabetes Obes Metab
, vol.18
, pp. 581-589
-
-
Skov, J.1
Pedersen, M.2
Holst, J.J.3
-
73
-
-
85026289827
-
Postprandial renal haemodynamic effect of lixisenatide vs once-daily insulin-glulisine in patients with type 2 diabetes on insulin-glargine: an 8-week, randomised, open-label trial
-
Tonneijck, L, Muskiet, MHA, Smits, MM, et al. Postprandial renal haemodynamic effect of lixisenatide vs once-daily insulin-glulisine in patients with type 2 diabetes on insulin-glargine: an 8-week, randomised, open-label trial. Diabetes Obes Metab 19 (2017), 1669–1680.
-
(2017)
Diabetes Obes Metab
, vol.19
, pp. 1669-1680
-
-
Tonneijck, L.1
Muskiet, M.H.A.2
Smits, M.M.3
-
74
-
-
84962135632
-
Acute renal effects of the GLP-1 receptor agonist exenatide in overweight type 2 diabetes patients: a randomised, double-blind, placebo-controlled trial
-
Tonneijck, L, Smits, MM, Muskiet, MHA, et al. Acute renal effects of the GLP-1 receptor agonist exenatide in overweight type 2 diabetes patients: a randomised, double-blind, placebo-controlled trial. Diabetologia 59 (2016), 1412–1421.
-
(2016)
Diabetologia
, vol.59
, pp. 1412-1421
-
-
Tonneijck, L.1
Smits, M.M.2
Muskiet, M.H.A.3
-
75
-
-
84994361897
-
Renal effects of DPP-4 inhibitor sitagliptin or GLP-1 receptor agonist liraglutide in overweight patients with type 2 diabetes: a 12-week, randomized, double-blind, placebo-controlled trial
-
Tonneijck, L, Smits, MM, Muskiet, MH, et al. Renal effects of DPP-4 inhibitor sitagliptin or GLP-1 receptor agonist liraglutide in overweight patients with type 2 diabetes: a 12-week, randomized, double-blind, placebo-controlled trial. Diabetes Care 39 (2016), 2042–2050.
-
(2016)
Diabetes Care
, vol.39
, pp. 2042-2050
-
-
Tonneijck, L.1
Smits, M.M.2
Muskiet, M.H.3
-
77
-
-
84940665526
-
Efficacy of liraglutide for weight loss among patients with type 2 diabetes: the SCALE diabetes randomized clinical trial
-
Davies, MJ, Bergenstal, R, Bode, B, et al. Efficacy of liraglutide for weight loss among patients with type 2 diabetes: the SCALE diabetes randomized clinical trial. JAMA 314 (2015), 687–699.
-
(2015)
JAMA
, vol.314
, pp. 687-699
-
-
Davies, M.J.1
Bergenstal, R.2
Bode, B.3
-
78
-
-
84962052167
-
Efficacy and safety of liraglutide versus placebo as add-on to glucose-lowering therapy in patients with type 2 diabetes and moderate renal impairment (LIRA-RENAL): a randomized clinical trial
-
Davies, MJ, Bain, SC, Atkin, SL, et al. Efficacy and safety of liraglutide versus placebo as add-on to glucose-lowering therapy in patients with type 2 diabetes and moderate renal impairment (LIRA-RENAL): a randomized clinical trial. Diabetes Care 39 (2016), 222–230.
-
(2016)
Diabetes Care
, vol.39
, pp. 222-230
-
-
Davies, M.J.1
Bain, S.C.2
Atkin, S.L.3
-
79
-
-
85005929975
-
The effect of liraglutide on renal function: a randomized clinical trial
-
von Scholten, BJ, Persson, F, Rosenlund, S, et al. The effect of liraglutide on renal function: a randomized clinical trial. Diabetes Obes Metab 19 (2017), 239–247.
-
(2017)
Diabetes Obes Metab
, vol.19
, pp. 239-247
-
-
von Scholten, B.J.1
Persson, F.2
Rosenlund, S.3
-
80
-
-
85013989186
-
Effects of once-weekly dulaglutide on kidney function in patients with type 2 diabetes in phase II and III clinical trials
-
Tuttle, KR, McKinney, TD, Davidson, JA, Anglin, G, Harper, KD, Botros, FT, Effects of once-weekly dulaglutide on kidney function in patients with type 2 diabetes in phase II and III clinical trials. Diabetes Obes Metab 19 (2017), 436–441.
-
(2017)
Diabetes Obes Metab
, vol.19
, pp. 436-441
-
-
Tuttle, K.R.1
McKinney, T.D.2
Davidson, J.A.3
Anglin, G.4
Harper, K.D.5
Botros, F.T.6
-
81
-
-
85048436169
-
Dulaglutide versus insulin glargine in patients with type 2 diabetes and moderate-to-severe chronic kidney disease (AWARD-7): a multicentre, open-label, randomised trial
-
Tuttle, KR, Lakshmanan, MC, Rayner, B, et al. Dulaglutide versus insulin glargine in patients with type 2 diabetes and moderate-to-severe chronic kidney disease (AWARD-7): a multicentre, open-label, randomised trial. Lancet Diabetes Endocrinol 6 (2018), 605–617.
-
(2018)
Lancet Diabetes Endocrinol
, vol.6
, pp. 605-617
-
-
Tuttle, K.R.1
Lakshmanan, M.C.2
Rayner, B.3
-
82
-
-
84948740668
-
Lixisenatide in patients with type 2 diabetes and acute coronary syndrome
-
Pfeffer, MA, Claggett, B, Diaz, R, et al. Lixisenatide in patients with type 2 diabetes and acute coronary syndrome. N Engl J Med 373 (2015), 2247–2257.
-
(2015)
N Engl J Med
, vol.373
, pp. 2247-2257
-
-
Pfeffer, M.A.1
Claggett, B.2
Diaz, R.3
-
83
-
-
85055612603
-
Lixisenatide and renal outcomes in patients with type 2 diabetes and acute coronary syndrome: an exploratory analysis of the ELIXA randomised, placebo-controlled trial
-
Muskiet, MHA, Tonneijck, L, Huang, Y, et al. Lixisenatide and renal outcomes in patients with type 2 diabetes and acute coronary syndrome: an exploratory analysis of the ELIXA randomised, placebo-controlled trial. Lancet Diabetes Endocrinol 6 (2018), 859–869.
-
(2018)
Lancet Diabetes Endocrinol
, vol.6
, pp. 859-869
-
-
Muskiet, M.H.A.1
Tonneijck, L.2
Huang, Y.3
-
84
-
-
85028547742
-
Liraglutide and renal outcomes in type 2 diabetes
-
Mann, JFE, Orsted, DD, Brown-Frandsen, K, et al. Liraglutide and renal outcomes in type 2 diabetes. N Engl J Med 377 (2017), 839–848.
-
(2017)
N Engl J Med
, vol.377
, pp. 839-848
-
-
Mann, J.F.E.1
Orsted, D.D.2
Brown-Frandsen, K.3
-
85
-
-
85055101508
-
Albiglutide and cardiovascular outcomes in patients with type 2 diabetes and cardiovascular disease (Harmony Outcomes): a double-blind, randomised placebo-controlled trial
-
Hernandez, AF, Green, JB, Janmohamed, S, et al. Albiglutide and cardiovascular outcomes in patients with type 2 diabetes and cardiovascular disease (Harmony Outcomes): a double-blind, randomised placebo-controlled trial. Lancet 392 (2018), 1519–1529.
-
(2018)
Lancet
, vol.392
, pp. 1519-1529
-
-
Hernandez, A.F.1
Green, J.B.2
Janmohamed, S.3
-
86
-
-
84994813253
-
Semaglutide and cardiovascular outcomes in patients with type 2 diabetes
-
Marso, SP, Bain, SC, Consoli, A, et al. Semaglutide and cardiovascular outcomes in patients with type 2 diabetes. N Engl J Med 375 (2016), 1834–1844.
-
(2016)
N Engl J Med
, vol.375
, pp. 1834-1844
-
-
Marso, S.P.1
Bain, S.C.2
Consoli, A.3
-
87
-
-
85028547742
-
Liraglutide and renal outcomes in type 2 diabetes
-
Mann, JFE, Orsted, DD, Buse, JB, Liraglutide and renal outcomes in type 2 diabetes. N Engl J Med 377 (2017), 2197–2198.
-
(2017)
N Engl J Med
, vol.377
, pp. 2197-2198
-
-
Mann, J.F.E.1
Orsted, D.D.2
Buse, J.B.3
-
88
-
-
84939565970
-
Kidney disease end points in a pooled analysis of individual patient-level data from a large clinical trials program of the dipeptidyl peptidase 4 inhibitor linagliptin in type 2 diabetes
-
Cooper, ME, Perkovic, V, McGill, JB, et al. Kidney disease end points in a pooled analysis of individual patient-level data from a large clinical trials program of the dipeptidyl peptidase 4 inhibitor linagliptin in type 2 diabetes. Am J Kidney Dis 66 (2015), 441–449.
-
(2015)
Am J Kidney Dis
, vol.66
, pp. 441-449
-
-
Cooper, M.E.1
Perkovic, V.2
McGill, J.B.3
-
89
-
-
84890476805
-
Linagliptin lowers albuminuria on top of recommended standard treatment in patients with type 2 diabetes and renal dysfunction
-
Groop, PH, Cooper, ME, Perkovic, V, Emser, A, Woerle, HJ, von Eynatten, M, Linagliptin lowers albuminuria on top of recommended standard treatment in patients with type 2 diabetes and renal dysfunction. Diabetes Care 36 (2013), 3460–3468.
-
(2013)
Diabetes Care
, vol.36
, pp. 3460-3468
-
-
Groop, P.H.1
Cooper, M.E.2
Perkovic, V.3
Emser, A.4
Woerle, H.J.5
von Eynatten, M.6
-
90
-
-
85026454641
-
Linagliptin and its effects on hyperglycaemia and albuminuria in patients with type 2 diabetes and renal dysfunction: the randomized MARLINA-T2D trial
-
Groop, PH, Cooper, ME, Perkovic, V, et al. Linagliptin and its effects on hyperglycaemia and albuminuria in patients with type 2 diabetes and renal dysfunction: the randomized MARLINA-T2D trial. Diabetes Obes Metab 19 (2017), 1610–1619.
-
(2017)
Diabetes Obes Metab
, vol.19
, pp. 1610-1619
-
-
Groop, P.H.1
Cooper, M.E.2
Perkovic, V.3
-
91
-
-
85008230357
-
Effect of saxagliptin on renal outcomes in the SAVOR-TIMI 53 trial
-
Mosenzon, O, Leibowitz, G, Bhatt, DL, et al. Effect of saxagliptin on renal outcomes in the SAVOR-TIMI 53 trial. Diabetes Care 40 (2017), 69–76.
-
(2017)
Diabetes Care
, vol.40
, pp. 69-76
-
-
Mosenzon, O.1
Leibowitz, G.2
Bhatt, D.L.3
-
92
-
-
84937053742
-
Effect of sitagliptin on cardiovascular outcomes in type 2 diabetes
-
Green, JB, Bethel, MA, Armstrong, PW, et al. Effect of sitagliptin on cardiovascular outcomes in type 2 diabetes. N Engl J Med 373 (2015), 232–242.
-
(2015)
N Engl J Med
, vol.373
, pp. 232-242
-
-
Green, J.B.1
Bethel, M.A.2
Armstrong, P.W.3
-
93
-
-
85029218795
-
A randomized, placebo-controlled study of the cardiovascular safety of the once-weekly DPP-4 inhibitor omarigliptin in patients with type 2 diabetes mellitus
-
Gantz, I, Chen, M, Suryawanshi, S, et al. A randomized, placebo-controlled study of the cardiovascular safety of the once-weekly DPP-4 inhibitor omarigliptin in patients with type 2 diabetes mellitus. Cardiovasc Diabetol, 16, 2017, 112.
-
(2017)
Cardiovasc Diabetol
, vol.16
, pp. 112
-
-
Gantz, I.1
Chen, M.2
Suryawanshi, S.3
-
94
-
-
85056408909
-
Effect of linagliptin vs placebo on major cardiovascular events in adults with type 2 diabetes and high cardiovascular and renal risk: the CARMELINA randomized clinical trial
-
published online Nov 9.
-
Rosenstock, J, Perkovic, V, Johansen, OE, et al. Effect of linagliptin vs placebo on major cardiovascular events in adults with type 2 diabetes and high cardiovascular and renal risk: the CARMELINA randomized clinical trial. JAMA, 2018 published online Nov 9. DOI:10.1001/jama.2018.18269.
-
(2018)
JAMA
-
-
Rosenstock, J.1
Perkovic, V.2
Johansen, O.E.3
-
95
-
-
48849094089
-
Endothelin: 20 years from discovery to therapy
-
Barton, M, Yanagisawa, M, Endothelin: 20 years from discovery to therapy. Can J Physiol Pharmacol 86 (2008), 485–498.
-
(2008)
Can J Physiol Pharmacol
, vol.86
, pp. 485-498
-
-
Barton, M.1
Yanagisawa, M.2
-
96
-
-
78751672175
-
Regulation of blood pressure and salt homeostasis by endothelin
-
Kohan, DE, Rossi, NF, Inscho, EW, Pollock, DM, Regulation of blood pressure and salt homeostasis by endothelin. Physiol Rev 91 (2011), 1–77.
-
(2011)
Physiol Rev
, vol.91
, pp. 1-77
-
-
Kohan, D.E.1
Rossi, N.F.2
Inscho, E.W.3
Pollock, D.M.4
-
97
-
-
84880402164
-
Myocardial, smooth muscle, nephron, and collecting duct gene targeting reveals the organ sites of endothelin A receptor antagonist fluid retention
-
Stuart, D, Chapman, M, Rees, S, Woodward, S, Kohan, DE, Myocardial, smooth muscle, nephron, and collecting duct gene targeting reveals the organ sites of endothelin A receptor antagonist fluid retention. J Pharmacol Exp Ther 346 (2013), 182–189.
-
(2013)
J Pharmacol Exp Ther
, vol.346
, pp. 182-189
-
-
Stuart, D.1
Chapman, M.2
Rees, S.3
Woodward, S.4
Kohan, D.E.5
-
98
-
-
84870329393
-
Disruption of the endothelin A receptor in the nephron causes mild fluid volume expansion
-
Stuart, D, Rees, S, Woodward, SK, Koesters, R, Strait, KA, Kohan, DE, Disruption of the endothelin A receptor in the nephron causes mild fluid volume expansion. BMC Nephrol, 13, 2012, 166.
-
(2012)
BMC Nephrol
, vol.13
, pp. 166
-
-
Stuart, D.1
Rees, S.2
Woodward, S.K.3
Koesters, R.4
Strait, K.A.5
Kohan, D.E.6
-
99
-
-
84908563167
-
Endothelin and endothelin antagonists in chronic kidney disease
-
Kohan, DE, Barton, M, Endothelin and endothelin antagonists in chronic kidney disease. Kidney Int 86 (2014), 896–904.
-
(2014)
Kidney Int
, vol.86
, pp. 896-904
-
-
Kohan, D.E.1
Barton, M.2
-
100
-
-
79959526176
-
Distinct actions of endothelin A-selective versus combined endothelin A/B receptor antagonists in early diabetic kidney disease
-
Saleh, MA, Pollock, JS, Pollock, DM, Distinct actions of endothelin A-selective versus combined endothelin A/B receptor antagonists in early diabetic kidney disease. J Pharmacol Exp Ther 338 (2011), 263–270.
-
(2011)
J Pharmacol Exp Ther
, vol.338
, pp. 263-270
-
-
Saleh, M.A.1
Pollock, J.S.2
Pollock, D.M.3
-
101
-
-
36749089567
-
Haemodynamic and renal effects of endothelin receptor antagonism in patients with chronic kidney disease
-
Dhaun, N, Ferro, CJ, Davenport, AP, Haynes, WG, Goddard, J, Webb, DJ, Haemodynamic and renal effects of endothelin receptor antagonism in patients with chronic kidney disease. Nephrol Dial Transplant 22 (2007), 3228–3234.
-
(2007)
Nephrol Dial Transplant
, vol.22
, pp. 3228-3234
-
-
Dhaun, N.1
Ferro, C.J.2
Davenport, A.P.3
Haynes, W.G.4
Goddard, J.5
Webb, D.J.6
-
102
-
-
67649859521
-
Blood pressure-independent reduction in proteinuria and arterial stiffness after acute endothelin-a receptor antagonism in chronic kidney disease
-
Dhaun, N, Macintyre, IM, Melville, V, et al. Blood pressure-independent reduction in proteinuria and arterial stiffness after acute endothelin-a receptor antagonism in chronic kidney disease. Hypertension 54 (2009), 113–119.
-
(2009)
Hypertension
, vol.54
, pp. 113-119
-
-
Dhaun, N.1
Macintyre, I.M.2
Melville, V.3
-
103
-
-
84980411187
-
Atrasentan reduces albuminuria by restoring the glomerular endothelial glycocalyx barrier in diabetic nephropathy
-
Boels, MG, Avramut, MC, Koudijs, A, et al. Atrasentan reduces albuminuria by restoring the glomerular endothelial glycocalyx barrier in diabetic nephropathy. Diabetes 65 (2016), 2429–2439.
-
(2016)
Diabetes
, vol.65
, pp. 2429-2439
-
-
Boels, M.G.1
Avramut, M.C.2
Koudijs, A.3
-
104
-
-
84898917512
-
Endothelin and the podocyte
-
Barton, M, Tharaux, PL, Endothelin and the podocyte. Clin Kidney J 5 (2012), 17–27.
-
(2012)
Clin Kidney J
, vol.5
, pp. 17-27
-
-
Barton, M.1
Tharaux, P.L.2
-
105
-
-
0031590298
-
Angiotensin II increases vascular and renal endothelin-1 and functional endothelin converting enzyme activity in vivo: role of ETA receptors for endothelin regulation
-
Barton, M, Shaw, S, d'Uscio, LV, Moreau, P, Luscher, TF, Angiotensin II increases vascular and renal endothelin-1 and functional endothelin converting enzyme activity in vivo: role of ETA receptors for endothelin regulation. Biochem Biophys Res Commun 238 (1997), 861–865.
-
(1997)
Biochem Biophys Res Commun
, vol.238
, pp. 861-865
-
-
Barton, M.1
Shaw, S.2
d'Uscio, L.V.3
Moreau, P.4
Luscher, T.F.5
-
106
-
-
62149126622
-
Avosentan reduces albumin excretion in diabetics with macroalbuminuria
-
Wenzel, RR, Littke, T, Kuranoff, S, et al. Avosentan reduces albumin excretion in diabetics with macroalbuminuria. J Am Soc Nephrol 20 (2009), 655–664.
-
(2009)
J Am Soc Nephrol
, vol.20
, pp. 655-664
-
-
Wenzel, R.R.1
Littke, T.2
Kuranoff, S.3
-
107
-
-
84906540059
-
The endothelin antagonist atrasentan lowers residual albuminuria in patients with type 2 diabetic nephropathy
-
de Zeeuw, D, Coll, B, Andress, D, et al. The endothelin antagonist atrasentan lowers residual albuminuria in patients with type 2 diabetic nephropathy. J Am Soc Nephrol 25 (2014), 1083–1093.
-
(2014)
J Am Soc Nephrol
, vol.25
, pp. 1083-1093
-
-
de Zeeuw, D.1
Coll, B.2
Andress, D.3
-
108
-
-
85043400847
-
Rationale and protocol of the study of diabetic nephropathy with atrasentan (SONAR) trial: a clinical trial design novel to diabetic nephropathy
-
Heerspink, HJL, Andress, DL, Bakris, G, et al. Rationale and protocol of the study of diabetic nephropathy with atrasentan (SONAR) trial: a clinical trial design novel to diabetic nephropathy. Diabetes Obes Metab 20 (2018), 1369–1376.
-
(2018)
Diabetes Obes Metab
, vol.20
, pp. 1369-1376
-
-
Heerspink, H.J.L.1
Andress, D.L.2
Bakris, G.3
-
109
-
-
0035068501
-
Aldosterone as a mediator of progressive renal disease: pathogenetic and clinical implications
-
Epstein, M, Aldosterone as a mediator of progressive renal disease: pathogenetic and clinical implications. Am J Kidney Dis 37 (2001), 677–688.
-
(2001)
Am J Kidney Dis
, vol.37
, pp. 677-688
-
-
Epstein, M.1
-
110
-
-
84856339877
-
Aldosterone, mineralocorticoid receptor, and heart failure
-
Messaoudi, S, Azibani, F, Delcayre, C, Jaisser, F, Aldosterone, mineralocorticoid receptor, and heart failure. Mol Cell Endocrinol 350 (2012), 266–272.
-
(2012)
Mol Cell Endocrinol
, vol.350
, pp. 266-272
-
-
Messaoudi, S.1
Azibani, F.2
Delcayre, C.3
Jaisser, F.4
-
111
-
-
70049108525
-
Aldosterone antagonists for preventing the progression of chronic kidney disease
-
CD007004.
-
Bolignano, D, Palmer, SC, Navaneethan, SD, Strippoli, GF, Aldosterone antagonists for preventing the progression of chronic kidney disease. Cochrane Database Syst Rev, 4, 2014 CD007004.
-
(2014)
Cochrane Database Syst Rev
, vol.4
-
-
Bolignano, D.1
Palmer, S.C.2
Navaneethan, S.D.3
Strippoli, G.F.4
-
112
-
-
0035922443
-
Spironolactone in addition to ACE inhibition to reduce proteinuria in patients with chronic renal disease
-
Chrysostomou, A, Becker, G, Spironolactone in addition to ACE inhibition to reduce proteinuria in patients with chronic renal disease. N Engl J Med 345 (2001), 925–926.
-
(2001)
N Engl J Med
, vol.345
, pp. 925-926
-
-
Chrysostomou, A.1
Becker, G.2
-
113
-
-
33750331264
-
Selective aldosterone blockade with eplerenone reduces albuminuria in patients with type 2 diabetes
-
Epstein, M, Williams, GH, Weinberger, M, et al. Selective aldosterone blockade with eplerenone reduces albuminuria in patients with type 2 diabetes. Clin J Am Soc Nephrol 1 (2006), 940–951.
-
(2006)
Clin J Am Soc Nephrol
, vol.1
, pp. 940-951
-
-
Epstein, M.1
Williams, G.H.2
Weinberger, M.3
-
114
-
-
84874521311
-
Renoprotective effects of mineralocorticoid receptor blockers in patients with proteinuric kidney diseases
-
Morales, E, Millet, VG, Rojas-Rivera, J, et al. Renoprotective effects of mineralocorticoid receptor blockers in patients with proteinuric kidney diseases. Nephrol Dial Transplant 28 (2013), 405–412.
-
(2013)
Nephrol Dial Transplant
, vol.28
, pp. 405-412
-
-
Morales, E.1
Millet, V.G.2
Rojas-Rivera, J.3
-
115
-
-
84903955528
-
Prediction and management of hyperkalemia across the spectrum of chronic kidney disease
-
Lazich, I, Bakris, GL, Prediction and management of hyperkalemia across the spectrum of chronic kidney disease. Semin Nephrol 34 (2014), 333–339.
-
(2014)
Semin Nephrol
, vol.34
, pp. 333-339
-
-
Lazich, I.1
Bakris, G.L.2
-
116
-
-
38149030811
-
Change in proteinuria after adding aldosterone blockers to ACE inhibitors or angiotensin receptor blockers in CKD: a systematic review
-
Bomback, AS, Kshirsagar, AV, Amamoo, MA, Klemmer, PJ, Change in proteinuria after adding aldosterone blockers to ACE inhibitors or angiotensin receptor blockers in CKD: a systematic review. Am J Kidney Dis 51 (2008), 199–211.
-
(2008)
Am J Kidney Dis
, vol.51
, pp. 199-211
-
-
Bomback, A.S.1
Kshirsagar, A.V.2
Amamoo, M.A.3
Klemmer, P.J.4
-
117
-
-
84870432435
-
Management of hyperkalaemia consequent to mineralocorticoid-receptor antagonist therapy
-
Roscioni, SS, de Zeeuw, D, Bakker, SJ, Lambers Heerspink, HJ, Management of hyperkalaemia consequent to mineralocorticoid-receptor antagonist therapy. Nat Rev Nephrol 8 (2012), 691–699.
-
(2012)
Nat Rev Nephrol
, vol.8
, pp. 691-699
-
-
Roscioni, S.S.1
de Zeeuw, D.2
Bakker, S.J.3
Lambers Heerspink, H.J.4
-
118
-
-
84856337738
-
Molecular pharmacology of the mineralocorticoid receptor: prospects for novel therapeutics
-
Kolkhof, P, Borden, SA, Molecular pharmacology of the mineralocorticoid receptor: prospects for novel therapeutics. Mol Cell Endocrinol 350 (2012), 310–317.
-
(2012)
Mol Cell Endocrinol
, vol.350
, pp. 310-317
-
-
Kolkhof, P.1
Borden, S.A.2
-
119
-
-
84861554853
-
Discovery of BAY 94-8862: a nonsteroidal antagonist of the mineralocorticoid receptor for the treatment of cardiorenal diseases
-
Barfacker, L, Kuhl, A, Hillisch, A, et al. Discovery of BAY 94-8862: a nonsteroidal antagonist of the mineralocorticoid receptor for the treatment of cardiorenal diseases. ChemMedChem 7 (2012), 1385–1403.
-
(2012)
ChemMedChem
, vol.7
, pp. 1385-1403
-
-
Barfacker, L.1
Kuhl, A.2
Hillisch, A.3
-
120
-
-
84940729269
-
Effect of finerenone on albuminuria in patients with diabetic nephropathy: a randomized clinical trial
-
Bakris, GL, Agarwal, R, Chan, JC, et al. Effect of finerenone on albuminuria in patients with diabetic nephropathy: a randomized clinical trial. JAMA 314 (2015), 884–894.
-
(2015)
JAMA
, vol.314
, pp. 884-894
-
-
Bakris, G.L.1
Agarwal, R.2
Chan, J.C.3
-
121
-
-
84896491806
-
The many faces of diabetes: a disease with increasing heterogeneity
-
Tuomi, T, Santoro, N, Caprio, S, Cai, M, Weng, J, Groop, L, The many faces of diabetes: a disease with increasing heterogeneity. Lancet 383 (2014), 1084–1094.
-
(2014)
Lancet
, vol.383
, pp. 1084-1094
-
-
Tuomi, T.1
Santoro, N.2
Caprio, S.3
Cai, M.4
Weng, J.5
Groop, L.6
-
122
-
-
85027191186
-
Renal trials in diabetes need a platform: time for a global approach?
-
de Zeeuw, D, Heerspink, HJL, Jardine, M, Perkovic, V, Renal trials in diabetes need a platform: time for a global approach?. Lancet Diabetes Endocrinol 6 (2018), 356–358.
-
(2018)
Lancet Diabetes Endocrinol
, vol.6
, pp. 356-358
-
-
de Zeeuw, D.1
Heerspink, H.J.L.2
Jardine, M.3
Perkovic, V.4
-
123
-
-
85053563266
-
SGLT2 inhibitors in combination therapy: from mechanisms to clinical considerations in type 2 diabetes management
-
van Baar, MJB, van Ruiten, CC, Muskiet, MHA, van Bloemendaal, L, IJzerman van, RG, Raalte, DH, SGLT2 inhibitors in combination therapy: from mechanisms to clinical considerations in type 2 diabetes management. Diabetes Care 41 (2018), 1543–1556.
-
(2018)
Diabetes Care
, vol.41
, pp. 1543-1556
-
-
van Baar, M.J.B.1
van Ruiten, C.C.2
Muskiet, M.H.A.3
van Bloemendaal, L.4
IJzerman van, R.G.5
Raalte, D.H.6
-
124
-
-
84994508611
-
Exenatide once weekly plus dapagliflozin once daily versus exenatide or dapagliflozin alone in patients with type 2 diabetes inadequately controlled with metformin monotherapy (DURATION-8): a 28 week, multicentre, double-blind, phase 3, randomised controlled trial
-
Frias, JP, Guja, C, Hardy, E, et al. Exenatide once weekly plus dapagliflozin once daily versus exenatide or dapagliflozin alone in patients with type 2 diabetes inadequately controlled with metformin monotherapy (DURATION-8): a 28 week, multicentre, double-blind, phase 3, randomised controlled trial. Lancet Diabetes Endocrinol 4 (2016), 1004–1016.
-
(2016)
Lancet Diabetes Endocrinol
, vol.4
, pp. 1004-1016
-
-
Frias, J.P.1
Guja, C.2
Hardy, E.3
-
125
-
-
85042458412
-
Dulaglutide as add-on therapy to SGLT2 inhibitors in patients with inadequately controlled type 2 diabetes (AWARD-10): a 24-week, randomised, double-blind, placebo-controlled trial
-
Ludvik, B, Frias, JP, Tinahones, FJ, et al. Dulaglutide as add-on therapy to SGLT2 inhibitors in patients with inadequately controlled type 2 diabetes (AWARD-10): a 24-week, randomised, double-blind, placebo-controlled trial. Lancet Diabetes Endocrinol 6 (2018), 370–381.
-
(2018)
Lancet Diabetes Endocrinol
, vol.6
, pp. 370-381
-
-
Ludvik, B.1
Frias, J.P.2
Tinahones, F.J.3
|