Simultaneously down-regulation of multiplex branch pathways using CRISPRi and fermentation optimization for enhancing β-amyrin production in Saccharomyces cerevisiae

Synthetic and Systems Biotechnology

Volumn 4, Issue 2, 2019, Pages 79-85

  Ni, Jiangping ^a   Zhang, Genlin ^b   Qin, Lei ^a   Li, Jun ^a   Li, Chun ^a  

^a BEIJING INSTITUTE OF TECHNOLOGY   (China)

^b SHIHEZI UNIVERSITY   (China)

Author keywords

CRISPRi; Saccharomyces cerevisiae; Transcriptional regulation; amyrin

Indexed keywords

ACETIC ACID DERIVATIVE; ACETYL COENZYME A; ALCOHOL DEHYDROGENASE; ALDEHYDE DEHYDROGENASE; BETA AMYRIN; BETA GALACTOSIDASE; DNA DIRECTED RNA POLYMERASE III; GLUCOSE; METHYL BETA CYCLODEXTRIN; PYRUVATE DEHYDROGENASE; SMALL NUCLEOLAR RNA;

ADH1 GENE; ADH4 GENE; ADH5 GENE; ADH6 GENE; ARTICLE; BIOSYNTHESIS; CELL GROWTH; CELL METABOLISM; CIT2 GENE; CLUSTERED REGULARLY INTERSPACED SHORT PALINDROMIC REPEAT; CONTROLLED STUDY; DNA STRAND; DOWN REGULATION; ERG7 GENE; FED BATCH FERMENTATION; FERMENTATION OPTIMIZATION; GENE; MLS2 GENE; NONHUMAN; NUCLEAR LOCALIZATION SIGNAL; PROMOTER REGION; SACCHAROMYCES CEREVISIAE;

EID: 85061794836     PISSN: None     EISSN: 2405805X     Source Type: Journal    
DOI: 10.1016/j.synbio.2019.02.002     Document Type: Article

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