Leveraging Polygenic Functional Enrichment to Improve GWAS Power

American Journal of Human Genetics

Volumn 104, Issue 1, 2019, Pages 65-75

  Kichaev, Gleb ^a   Bhatia, Gaurav ^b   Loh, Po Ru ^b,c   Gazal, Steven ^b,c   Burch, Kathryn ^a   Freund, Malika K ^d   Schoech, Armin ^b,c   Pasaniuc, Bogdan ^a,d   Price, Alkes L ^b,c  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b HARVARD SCHOOL OF PUBLIC HEALTH   (United States)

^c BROAD INSTITUTE OF MIT AND HARVARD   (United States)

^d UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

complex traits; functional genomics; GWAS

Indexed keywords

ARTICLE; BIOBANK; FUNCTIONAL ENRICHMENT; FUNCTIONAL GENOMICS; GENE LOCUS; GENETIC TRAIT; GENOME-WIDE ASSOCIATION STUDY; GENOTYPE; HUMAN; MOLECULAR GENETICS; MULTIFACTORIAL INHERITANCE; PRIORITY JOURNAL; SAMPLE SIZE; SIMULATION; SINGLE NUCLEOTIDE POLYMORPHISM; UNITED KINGDOM; CALIBRATION; FALSE POSITIVE RESULT; GENETIC DATABASE; GENETICS; INFORMATION PROCESSING; PROBABILITY; REPRODUCIBILITY;

CALIBRATION; DATABASES, GENETIC; DATASETS AS TOPIC; FALSE POSITIVE REACTIONS; GENOME-WIDE ASSOCIATION STUDY; HUMANS; MULTIFACTORIAL INHERITANCE; POLYMORPHISM, SINGLE NUCLEOTIDE; PROBABILITY; REPRODUCIBILITY OF RESULTS; UNITED KINGDOM;

EID: 85059493220     PISSN: 00029297     EISSN: 15376605     Source Type: Journal    
DOI: 10.1016/j.ajhg.2018.11.008     Document Type: Article

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