Leveraging molecular quantitative trait loci to understand the genetic architecture of diseases and complex traits

Nature Genetics

Volumn 50, Issue 7, 2018, Pages 1041-1047

  Hormozdiari, Farhad ^a,b   Gazal, Steven ^a,b   Van De Geijn, Bryce ^a,b   Finucane, Hilary K ^a,b   Ju, Chelsea J T ^c   Loh, Po Ru ^b,d   Schoech, Armin ^a,b   Reshef, Yakir ^a,b   Liu, Xuanyao ^a,b   O'connor, Luke ^a,e   Gusev, Alexander ^d,f   Eskin, Eleazar ^c,g   Price, Alkes L ^a,b  

^a HARVARD SCHOOL OF PUBLIC HEALTH   (United States)

^b BROAD INSTITUTE OF MIT AND HARVARD   (United States)

^c University of California   (United States)

^d BRIGHAM AND WOMEN S HOSPITAL   (United States)

^e HARVARD UNIVERSITY   (United States)

^f HARVARD MEDICAL SCHOOL   (United States)

^g UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

HISTONE;

ARTICLE; CANCER CELL LINE; DISEASE ASSOCIATION; EXPRESSION QUANTITATIVE TRAIT LOCUS; GENE EXPRESSION; GENETIC CORRELATION; HERITABILITY; HUMAN; HUMAN CELL; HUMAN TISSUE; MAJOR CLINICAL STUDY; MISSENSE MUTATION; PHENOTYPE; PRIORITY JOURNAL; QUANTITATIVE TRAIT LOCUS; SINGLE NUCLEOTIDE POLYMORPHISM; TISSUE SPECIFICITY; DISEASES; GENETICS; GENOME-WIDE ASSOCIATION STUDY; MULTIFACTORIAL INHERITANCE; PROCEDURES; QUANTITATIVE TRAIT;

DISEASE; GENOME-WIDE ASSOCIATION STUDY; HUMANS; MULTIFACTORIAL INHERITANCE; PHENOTYPE; POLYMORPHISM, SINGLE NUCLEOTIDE; QUANTITATIVE TRAIT LOCI; QUANTITATIVE TRAIT, HERITABLE;

EID: 85049003482     PISSN: 10614036     EISSN: 15461718     Source Type: Journal    
DOI: 10.1038/s41588-018-0148-2     Document Type: Article

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