Statistical correction of the Winner’s Curse explains replication variability in quantitative trait genome-wide association studies

PLoS Genetics

Volumn 13, Issue 7, 2017, Pages

  Palmer, Cameron ^a,b   Pe’er, Itsik ^b  

^a NewYork Presbyterian Hospital   (United States)

^b Columbia University ^*  (United States)

Author keywords

[No Author keywords available]

Indexed keywords

DATA BASE; EFFECT SIZE; EXPECTATION; GENE LINKAGE DISEQUILIBRIUM; GENOME-WIDE ASSOCIATION STUDY; HUMAN; MAJOR CLINICAL STUDY; QUANTITATIVE TRAIT; BIOLOGICAL MODEL; DNA REPLICATION; FACTUAL DATABASE; HUMAN GENOME; PHENOTYPE; QUANTITATIVE TRAIT LOCUS; SINGLE NUCLEOTIDE POLYMORPHISM; STATISTICAL MODEL;

DATABASES, FACTUAL; DNA REPLICATION; GENOME, HUMAN; GENOME-WIDE ASSOCIATION STUDY; HUMANS; LINEAR MODELS; LINKAGE DISEQUILIBRIUM; MODELS, GENETIC; PHENOTYPE; POLYMORPHISM, SINGLE NUCLEOTIDE; QUANTITATIVE TRAIT LOCI;

EID: 85026680175     PISSN: 15537390     EISSN: 15537404     Source Type: Journal    
DOI: 10.1371/journal.pgen.1006916     Document Type: Article

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