-
1
-
-
84929001104
-
Human genomics. The Genotype-Tissue Expression (GTEx) pilot analysis: Multitissue gene regulation in humans
-
K.G. Ardlie, D.S. Deluca, A.V. Segrè, T.J. Sullivan, T.R. Young, E.T. Gelfand, C.A. Trowbridge, J.B. Maller, T. Tukiainen, M. Lek, et al. GTEx Consortium Human genomics. The Genotype-Tissue Expression (GTEx) pilot analysis: multitissue gene regulation in humans Science 348 2015 648 660
-
(2015)
Science
, vol.348
, pp. 648-660
-
-
Ardlie, K.G.1
Deluca, D.S.2
Segrè, A.V.3
Sullivan, T.J.4
Young, T.R.5
Gelfand, E.T.6
Trowbridge, C.A.7
Maller, J.B.8
Tukiainen, T.9
Lek, M.10
-
2
-
-
84885645853
-
Transcriptome and genome sequencing uncovers functional variation in humans
-
T. Lappalainen, M. Sammeth, M.R. Friedländer, P.A. 't Hoen, J. Monlong, M.A. Rivas, M. Gonzàlez-Porta, N. Kurbatova, T. Griebel, P.G. Ferreira, et al. Geuvadis Consortium Transcriptome and genome sequencing uncovers functional variation in humans Nature 501 2013 506 511
-
(2013)
Nature
, vol.501
, pp. 506-511
-
-
Lappalainen, T.1
Sammeth, M.2
Friedländer, M.R.3
'T Hoen, P.A.4
Monlong, J.5
Rivas, M.A.6
Gonzàlez-Porta, M.7
Kurbatova, N.8
Griebel, T.9
Ferreira, P.G.10
-
3
-
-
84857111200
-
DNasecI sensitivity QTLs are a major determinant of human expression variation
-
J.F. Degner, A.A. Pai, R. Pique-Regi, J.-B. Veyrieras, D.J. Gaffney, J.K. Pickrell, S. De Leon, K. Michelini, N. Lewellen, G.E. Crawford, and et al. DNasecI sensitivity QTLs are a major determinant of human expression variation Nature 482 2012 390 394
-
(2012)
Nature
, vol.482
, pp. 390-394
-
-
Degner, J.F.1
Pai, A.A.2
Pique-Regi, R.3
Veyrieras, J.-B.4
Gaffney, D.J.5
Pickrell, J.K.6
De Leon, S.7
Michelini, K.8
Lewellen, N.9
Crawford, G.E.10
-
4
-
-
84887322043
-
Identification of genetic variants that affect histone modifications in human cells
-
G. McVicker, B. van de Geijn, J.F. Degner, C.E. Cain, N.E. Banovich, A. Raj, N. Lewellen, M. Myrthil, Y. Gilad, and J.K. Pritchard Identification of genetic variants that affect histone modifications in human cells Science 342 2013 747 749
-
(2013)
Science
, vol.342
, pp. 747-749
-
-
McVicker, G.1
Van De Geijn, B.2
Degner, J.F.3
Cain, C.E.4
Banovich, N.E.5
Raj, A.6
Lewellen, N.7
Myrthil, M.8
Gilad, Y.9
Pritchard, J.K.10
-
5
-
-
84907584646
-
Methylation QTLs are associated with coordinated changes in transcription factor binding, histone modifications, and gene expression levels
-
N.E. Banovich, X. Lan, G. McVicker, B. van de Geijn, J.F. Degner, J.D. Blischak, J. Roux, J.K. Pritchard, and Y. Gilad Methylation QTLs are associated with coordinated changes in transcription factor binding, histone modifications, and gene expression levels PLoS Genet. 10 2014 e1004663
-
(2014)
PLoS Genet.
, vol.10
, pp. e1004663
-
-
Banovich, N.E.1
Lan, X.2
McVicker, G.3
Van De Geijn, B.4
Degner, J.F.5
Blischak, J.D.6
Roux, J.7
Pritchard, J.K.8
Gilad, Y.9
-
6
-
-
84925089678
-
The role of regulatory variation in complex traits and disease
-
F.W. Albert, and L. Kruglyak The role of regulatory variation in complex traits and disease Nat. Rev. Genet. 16 2015 197 212
-
(2015)
Nat. Rev. Genet.
, vol.16
, pp. 197-212
-
-
Albert, F.W.1
Kruglyak, L.2
-
7
-
-
84865790047
-
An integrated encyclopedia of DNA elements in the human genome
-
ENCODE Project Consortium An integrated encyclopedia of DNA elements in the human genome Nature 489 2012 57 74
-
(2012)
Nature
, vol.489
, pp. 57-74
-
-
-
8
-
-
84923362619
-
Integrative analysis of 111 reference human epigenomes
-
A. Kundaje, W. Meuleman, J. Ernst, M. Bilenky, A. Yen, A. Heravi-Moussavi, P. Kheradpour, Z. Zhang, J. Wang, M.J. Ziller, et al. Roadmap Epigenomics Consortium Integrative analysis of 111 reference human epigenomes Nature 518 2015 317 330
-
(2015)
Nature
, vol.518
, pp. 317-330
-
-
Kundaje, A.1
Meuleman, W.2
Ernst, J.3
Bilenky, M.4
Yen, A.5
Heravi-Moussavi, A.6
Kheradpour, P.7
Zhang, Z.8
Wang, J.9
Ziller, M.J.10
-
9
-
-
55449112450
-
High-resolution mapping of expression-QTLs yields insight into human gene regulation
-
J.-B. Veyrieras, S. Kudaravalli, S.Y. Kim, E.T. Dermitzakis, Y. Gilad, M. Stephens, and J.K. Pritchard High-resolution mapping of expression-QTLs yields insight into human gene regulation PLoS Genet. 4 2008 e1000214
-
(2008)
PLoS Genet.
, vol.4
, pp. e1000214
-
-
Veyrieras, J.-B.1
Kudaravalli, S.2
Kim, S.Y.3
Dermitzakis, E.T.4
Gilad, Y.5
Stephens, M.6
Pritchard, J.K.7
-
10
-
-
84856321864
-
Dissecting the regulatory architecture of gene expression QTLs
-
D.J. Gaffney, J.-B. Veyrieras, J.F. Degner, R. Pique-Regi, A.A. Pai, G.E. Crawford, M. Stephens, Y. Gilad, and J.K. Pritchard Dissecting the regulatory architecture of gene expression QTLs Genome Biol. 13 2012 R7
-
(2012)
Genome Biol.
, vol.13
, pp. R7
-
-
Gaffney, D.J.1
Veyrieras, J.-B.2
Degner, J.F.3
Pique-Regi, R.4
Pai, A.A.5
Crawford, G.E.6
Stephens, M.7
Gilad, Y.8
Pritchard, J.K.9
-
11
-
-
84898723939
-
Joint analysis of functional genomic data and genome-wide association studies of 18 human traits
-
J.K. Pickrell Joint analysis of functional genomic data and genome-wide association studies of 18 human traits Am. J. Hum. Genet. 94 2014 559 573
-
(2014)
Am. J. Hum. Genet.
, vol.94
, pp. 559-573
-
-
Pickrell, J.K.1
-
12
-
-
84908324508
-
Integrating functional data to prioritize causal variants in statistical fine-mapping studies
-
G. Kichaev, W.-Y. Yang, S. Lindstrom, F. Hormozdiari, E. Eskin, A.L. Price, P. Kraft, and B. Pasaniuc Integrating functional data to prioritize causal variants in statistical fine-mapping studies PLoS Genet. 10 2014 e1004722
-
(2014)
PLoS Genet.
, vol.10
, pp. e1004722
-
-
Kichaev, G.1
Yang, W.-Y.2
Lindstrom, S.3
Hormozdiari, F.4
Eskin, E.5
Price, A.L.6
Kraft, P.7
Pasaniuc, B.8
-
13
-
-
84930368286
-
Cross-population joint analysis of eQTLs: Fine mapping and functional annotation
-
X. Wen, F. Luca, and R. Pique-Regi Cross-population joint analysis of eQTLs: fine mapping and functional annotation PLoS Genet. 11 2015 e1005176
-
(2015)
PLoS Genet.
, vol.11
, pp. e1005176
-
-
Wen, X.1
Luca, F.2
Pique-Regi, R.3
-
14
-
-
84971521649
-
Effective qtl discovery incorporating genomic annotations
-
X. Wen Effective qtl discovery incorporating genomic annotations bioRxiv 2015 10.1101/032003
-
(2015)
BioRxiv
-
-
Wen, X.1
-
15
-
-
84870502629
-
Bayesian refinement of association signals for 14 loci in 3 common diseases
-
J.B. Maller, G. McVean, J. Byrnes, D. Vukcevic, K. Palin, Z. Su, J.M. Howson, A. Auton, S. Myers, A. Morris, et al. Wellcome Trust Case Control Consortium Bayesian refinement of association signals for 14 loci in 3 common diseases Nat. Genet. 44 2012 1294 1301
-
(2012)
Nat. Genet.
, vol.44
, pp. 1294-1301
-
-
Maller, J.B.1
McVean, G.2
Byrnes, J.3
Vukcevic, D.4
Palin, K.5
Su, Z.6
Howson, J.M.7
Auton, A.8
Myers, S.9
Morris, A.10
-
16
-
-
82955223524
-
Bayesian variable selection regression for genome-wide association studies and other large-scale problems
-
Y. Guan, and M. Stephens Bayesian variable selection regression for genome-wide association studies and other large-scale problems Ann. Appl. Stat. 5 2011 1780 1815
-
(2011)
Ann. Appl. Stat.
, vol.5
, pp. 1780-1815
-
-
Guan, Y.1
Stephens, M.2
-
17
-
-
34547622688
-
Imputation-based analysis of association studies: Candidate regions and quantitative traits
-
B. Servin, and M. Stephens Imputation-based analysis of association studies: candidate regions and quantitative traits PLoS Genet. 3 2007 e114
-
(2007)
PLoS Genet.
, vol.3
, pp. e114
-
-
Servin, B.1
Stephens, M.2
-
18
-
-
84895881336
-
Bayesian model selection in complex linear systems, as illustrated in genetic association studies
-
X. Wen Bayesian model selection in complex linear systems, as illustrated in genetic association studies Biometrics 70 2014 73 83
-
(2014)
Biometrics
, vol.70
, pp. 73-83
-
-
Wen, X.1
-
19
-
-
77958516199
-
Bayesian model search and multilevel inference for snp association studies
-
M.A. Wilson, E.S. Iversen, M.A. Clyde, S.C. Schmidler, and J.M. Schildkraut Bayesian model search and multilevel inference for snp association studies Ann. Appl. Stat. 4 2010 1342 1364
-
(2010)
Ann. Appl. Stat.
, vol.4
, pp. 1342-1364
-
-
Wilson, M.A.1
Iversen, E.S.2
Clyde, M.A.3
Schmidler, S.C.4
Schildkraut, J.M.5
-
20
-
-
71849118573
-
High-resolution analysis of DNA regulatory elements by synthetic saturation mutagenesis
-
R.P. Patwardhan, C. Lee, O. Litvin, D.L. Young, D. Pe'er, and J. Shendure High-resolution analysis of DNA regulatory elements by synthetic saturation mutagenesis Nat. Biotechnol. 27 2009 1173 1175
-
(2009)
Nat. Biotechnol.
, vol.27
, pp. 1173-1175
-
-
Patwardhan, R.P.1
Lee, C.2
Litvin, O.3
Young, D.L.4
Pe'Er, D.5
Shendure, J.6
-
21
-
-
84907257107
-
Saturation editing of genomic regions by multiplex homology-directed repair
-
G.M. Findlay, E.A. Boyle, R.J. Hause, J.C. Klein, and J. Shendure Saturation editing of genomic regions by multiplex homology-directed repair Nature 513 2014 120 123
-
(2014)
Nature
, vol.513
, pp. 120-123
-
-
Findlay, G.M.1
Boyle, E.A.2
Hause, R.J.3
Klein, J.C.4
Shendure, J.5
-
22
-
-
84871615273
-
In vitro scan for enhancers at the TCF7L2 locus
-
D. Savic, S.Y. Park, K.A. Bailey, G.I. Bell, and M.A. Nobrega In vitro scan for enhancers at the TCF7L2 locus Diabetologia 56 2013 121 125
-
(2013)
Diabetologia
, vol.56
, pp. 121-125
-
-
Savic, D.1
Park, S.Y.2
Bailey, K.A.3
Bell, G.I.4
Nobrega, M.A.5
-
23
-
-
84878476783
-
A statistical framework for joint eQTL analysis in multiple tissues
-
T. Flutre, X. Wen, J. Pritchard, and M. Stephens A statistical framework for joint eQTL analysis in multiple tissues PLoS Genet. 9 2013 e1003486
-
(2013)
PLoS Genet.
, vol.9
, pp. e1003486
-
-
Flutre, T.1
Wen, X.2
Pritchard, J.3
Stephens, M.4
-
24
-
-
84861461948
-
Using linear predictors to impute allele frequencies from summary or pooled genotype data
-
X. Wen, and M. Stephens Using linear predictors to impute allele frequencies from summary or pooled genotype data Ann. Appl. Stat. 4 2010 1158 1182
-
(2010)
Ann. Appl. Stat.
, vol.4
, pp. 1158-1182
-
-
Wen, X.1
Stephens, M.2
-
25
-
-
84959919704
-
Approximately independent linkage disequilibrium blocks in human populations
-
T. Berisa, and J.K. Pickrell Approximately independent linkage disequilibrium blocks in human populations Bioinformatics 32 2016 283 285
-
(2016)
Bioinformatics
, vol.32
, pp. 283-285
-
-
Berisa, T.1
Pickrell, J.K.2
-
26
-
-
79952266465
-
Accurate inference of transcription factor binding from DNA sequence and chromatin accessibility data
-
R. Pique-Regi, J.F. Degner, A.A. Pai, D.J. Gaffney, Y. Gilad, and J.K. Pritchard Accurate inference of transcription factor binding from DNA sequence and chromatin accessibility data Genome Res. 21 2011 447 455
-
(2011)
Genome Res.
, vol.21
, pp. 447-455
-
-
Pique-Regi, R.1
Degner, J.F.2
Pai, A.A.3
Gaffney, D.J.4
Gilad, Y.5
Pritchard, J.K.6
-
27
-
-
84959924150
-
Which genetics variants in dnase-seq footprints are more likely to alter binding?
-
G.A. Moyerbrailean, C.A. Kalita, C.T. Harvey, X. Wen, F. Luca, and R. Pique-Regi Which genetics variants in dnase-seq footprints are more likely to alter binding? PLoS Genet. 12 2016 e1005875
-
(2016)
PLoS Genet.
, vol.12
, pp. e1005875
-
-
Moyerbrailean, G.A.1
Kalita, C.A.2
Harvey, C.T.3
Wen, X.4
Luca, F.5
Pique-Regi, R.6
-
28
-
-
77955499945
-
From noncoding variant to phenotype via SORT1 at the 1p13 cholesterol locus
-
K. Musunuru, A. Strong, M. Frank-Kamenetsky, N.E. Lee, T. Ahfeldt, K.V. Sachs, X. Li, H. Li, N. Kuperwasser, V.M. Ruda, and et al. From noncoding variant to phenotype via SORT1 at the 1p13 cholesterol locus Nature 466 2010 714 719
-
(2010)
Nature
, vol.466
, pp. 714-719
-
-
Musunuru, K.1
Strong, A.2
Frank-Kamenetsky, M.3
Lee, N.E.4
Ahfeldt, T.5
Sachs, K.V.6
Li, X.7
Li, H.8
Kuperwasser, N.9
Ruda, V.M.10
-
29
-
-
84874783818
-
Polygenic modeling with Bayesian sparse linear mixed models
-
X. Zhou, P. Carbonetto, and M. Stephens Polygenic modeling with bayesian sparse linear mixed models PLoS Genet. 9 2013 e1003264
-
(2013)
PLoS Genet.
, vol.9
, pp. e1003264
-
-
Zhou, X.1
Carbonetto, P.2
Stephens, M.3
-
30
-
-
0000298252
-
The intrinsic bayes factor for model selection and prediction
-
J.O. Berger, and L.R. Pericchi The intrinsic bayes factor for model selection and prediction J. Am. Stat. Assoc. 91 1996 109 122
-
(1996)
J. Am. Stat. Assoc.
, vol.91
, pp. 109-122
-
-
Berger, J.O.1
Pericchi, L.R.2
-
31
-
-
66049114148
-
Bayes factors for genome-wide association studies: Comparison with P-values
-
J. Wakefield Bayes factors for genome-wide association studies: comparison with P-values Genet. Epidemiol. 33 2009 79 86
-
(2009)
Genet. Epidemiol.
, vol.33
, pp. 79-86
-
-
Wakefield, J.1
-
32
-
-
84898024088
-
Bayesian methods for genetic association analysis with heterogeneous subgroups: From meta-analyses to gene-environment interactions
-
X. Wen, and M. Stephens Bayesian methods for genetic association analysis with heterogeneous subgroups: From meta-analyses to gene-environment interactions Ann. Appl. Stat. 8 2014 176 203
-
(2014)
Ann. Appl. Stat.
, vol.8
, pp. 176-203
-
-
Wen, X.1
Stephens, M.2
|