Stratified false discovery control for large-scale hypothesis testing with application to genome-wide association studies

Genetic Epidemiology

Volumn 30, Issue 6, 2006, Pages 519-530

  Sun, Lei ^a,b,d   Craiu, Radu V ^a   Paterson, Andrew D ^a,b   Bull, Shelley B ^a,c  

^a UNIVERSITY OF TORONTO   (Canada)

^b HOSPITAL FOR SICK CHILDREN   (Canada)

^c MOUNT SINAI HOSPITAL   (Canada)

^d Department of Public Health Sciences ^*  (Canada)

Author keywords

False discovery rate (FDR); Genome scans; Multiple comparisons; Power; Stratified FDR; Type I error; Type II error

Indexed keywords

ACCURACY; ARTICLE; AVERAGE; CONTROL STRATEGY; CONTROL SYSTEM; FALSE DISCOVERY RATE; FALSE POSITIVE RESULT; FIXED REJECTION REGION; GENETIC ANALYSIS; GENETIC ASSOCIATION; GENETIC LINKAGE; GENOME; GENOTYPE; HYPOTHESIS; HYPOTHESIS TESTING; STATISTICAL ANALYSIS; STATISTICAL SIGNIFICANCE;

CHROMOSOME MAPPING; DATA INTERPRETATION, STATISTICAL; DIABETES MELLITUS, TYPE 1; FALSE POSITIVE REACTIONS; GENETIC PREDISPOSITION TO DISEASE; GENOME, HUMAN; HUMANS; MODELS, GENETIC; PHENOTYPE; POLYMORPHISM, SINGLE NUCLEOTIDE; QUANTITATIVE TRAIT, HERITABLE;

EID: 33747595466     PISSN: 07410395     EISSN: 10982272     Source Type: Journal    
DOI: 10.1002/gepi.20164     Document Type: Article

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