Human respiratory syncytial virus NS 1 targets TRIM25 to suppress RIG-I ubiquitination and subsequent RIG-I-mediated antiviral signaling

Viruses

Volumn 10, Issue 12, 2018, Pages

  Ban, Junsu ^a   Lee, Na Rae ^a   Lee, Noh Jin ^a   Lee, Jong Kil ^a   Quan, Fu Shi ^a   Inn, Kyung Soo ^a  

^a Kyung Hee University Hospital   (South Korea)

Author keywords

Interferon; Nonstructural protein 1; Respiratory syncytial virus; RIG I; Trim25

Indexed keywords

BETA INTERFERON; COMPLEMENTARY DNA; MESSENGER RNA; NONSTRUCTURAL PROTEIN 1; TRIPARTITE MOTIF PROTEIN 5; DDX58 PROTEIN, HUMAN; PROTEIN BINDING; RETINOIC ACID INDUCIBLE PROTEIN I; TRANSCRIPTION FACTOR; TRIM25 PROTEIN, HUMAN; TRIPARTITE MOTIF PROTEIN; UBIQUITIN PROTEIN LIGASE; VIRAL PROTEIN;

A-549 CELL LINE; ANIMAL CELL; ARTICLE; CELL LYSATE; CONFOCAL MICROSCOPY; CONTROLLED STUDY; ECTOPIC EXPRESSION; GENETIC TRANSFECTION; HEK293T CELL LINE; HEP-2 CELL LINE; HUMAN; HUMAN CELL; HUMAN RESPIRATORY SYNCYTIAL VIRUS; IMMUNOBLOTTING; IMMUNOPRECIPITATION; LUCIFERASE ASSAY; MRNA EXPRESSION LEVEL; NONHUMAN; PLASMID; PROTEIN EXPRESSION; PROTEIN INTERACTION; REAL TIME POLYMERASE CHAIN REACTION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; RNA EXTRACTION; SIGNAL TRANSDUCTION; UBIQUITINATION; WESTERN BLOTTING; CELL LINE; GENETICS; HEK293 CELL LINE; IMMUNOLOGY; INNATE IMMUNITY; METABOLISM; PHYSIOLOGY; POLYMERASE CHAIN REACTION;

A549 CELLS; CELL LINE; DEAD BOX PROTEIN 58; HEK293 CELLS; HUMANS; IMMUNITY, INNATE; POLYMERASE CHAIN REACTION; PROTEIN BINDING; RESPIRATORY SYNCYTIAL VIRUS, HUMAN; SIGNAL TRANSDUCTION; TRANSCRIPTION FACTORS; TRIPARTITE MOTIF PROTEINS; UBIQUITIN-PROTEIN LIGASES; UBIQUITINATION; VIRAL NONSTRUCTURAL PROTEINS;

EID: 85058741112     PISSN: None     EISSN: 19994915     Source Type: Journal    
DOI: 10.3390/v10120716     Document Type: Article

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