Prelamin A accumulation attenuates Rac1 activity and increases the intrinsic migrational persistence of aged vascular smooth muscle cells

Cells

Volumn 5, Issue 4, 2016, Pages

  Porter, Lauren J ^a   Holt, Mark R ^b   Soong, Daniel ^a,c   Shanahan, Catherine M ^a   Warren, Derek T ^a,d  

^a KING'S COLLEGE LONDON   (United Kingdom)

^b KING'S COLLEGE LONDON   (United Kingdom)

^c UNIVERSITY OF EDINBURGH   (United Kingdom)

^d UNIVERSITY OF EAST ANGLIA   (United Kingdom)

Author keywords

Migratory persistence; Prelamin A; Rac1

Indexed keywords

FOCAL ADHESION KINASE 1; GLUTATHIONE TRANSFERASE; LAMIN A; LAMIN C; PRELAMIN A; RAC1 PROTEIN; UNCLASSIFIED DRUG;

ADULT; ARCHITECTURE; ARTICLE; CELL NUCLEUS MEMBRANE; CONTROLLED STUDY; DENSITOMETRY; EXTRACELLULAR MATRIX; FEMALE; GENOTYPE PHENOTYPE CORRELATION; HUMAN; HUMAN CELL; IMMUNOFLUORESCENCE MICROSCOPY; MALE; MIDDLE AGED; MORPHOLOGY; POLYMERASE CHAIN REACTION; TRABECULAR MESHWORK; VASCULAR SMOOTH MUSCLE CELL; WESTERN BLOTTING;

EID: 85056746493     PISSN: None     EISSN: 20734409     Source Type: Journal    
DOI: 10.3390/cells5040041     Document Type: Article

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