-
1
-
-
80051800674
-
Role of DNA damage in atherosclerosis-bystander or participant?
-
Gray K, Bennett M. Role of DNA damage in atherosclerosis-bystander or participant? Biochem Pharmacol 2011; 82: 693-700.
-
(2011)
Biochem Pharmacol
, vol.82
, pp. 693-700
-
-
Gray, K.1
Bennett, M.2
-
2
-
-
77953023624
-
Prelamin A acts to accelerate smooth muscle cell senescence and is a novel biomarker of human vascular aging
-
Ragnauth CD, Warren DT, Liu Y, McNair R, Tajsic T, Figg N et al. Prelamin A acts to accelerate smooth muscle cell senescence and is a novel biomarker of human vascular aging. Circulation 2010; 121: 2200-2210.
-
(2010)
Circulation
, vol.121
, pp. 2200-2210
-
-
Ragnauth, C.D.1
Warren, D.T.2
Liu, Y.3
McNair, R.4
Tajsic, T.5
Figg, N.6
-
3
-
-
84879808450
-
Prelamin A accelerates vascular calcification via activation of the DNA damage response and senescence-associated secretory phenotype in vascular smooth muscle cells
-
Liu Y, Drozdov I, Shroff R, Beltran LE, Shanahan CM. Prelamin A accelerates vascular calcification via activation of the DNA damage response and senescence-associated secretory phenotype in vascular smooth muscle cells. Circ Res 2013; 112: e99-109.
-
(2013)
Circ Res
, vol.112
, pp. e99-109
-
-
Liu, Y.1
Drozdov, I.2
Shroff, R.3
Beltran, L.E.4
Shanahan, C.M.5
-
4
-
-
84871501642
-
The nuclear lamins: Flexibility in function
-
Burke B, Stewart CL. The nuclear lamins: flexibility in function. Nat Rev Mol Cell Biol 2013; 14: 13-24.
-
(2013)
Nat Rev Mol Cell Biol
, vol.14
, pp. 13-24
-
-
Burke, B.1
Stewart, C.L.2
-
5
-
-
78549252392
-
Identification of differential protein interactors of lamin A and progerin
-
Kubben N, Voncken JW, Demmers J, Calis C, van Almen G, Pinto Y et al. Identification of differential protein interactors of lamin A and progerin. Nucleus 2010; 1: 513-525.
-
(2010)
Nucleus
, vol.1
, pp. 513-525
-
-
Kubben, N.1
Voncken, J.W.2
Demmers, J.3
Calis, C.4
Van Almen, G.5
Pinto, Y.6
-
6
-
-
84877071045
-
A-type lamins maintain the positional stability of DNA damage repair foci in mammalian nuclei
-
Mahen R, Hattori H, Lee M, Sharma P, Jeyasekharan AD, Venkitaraman AR. A-type lamins maintain the positional stability of DNA damage repair foci in mammalian nuclei. PLoS One 2013; 8: e61893.
-
(2013)
PLoS One
, vol.8
, pp. e61893
-
-
Mahen, R.1
Hattori, H.2
Lee, M.3
Sharma, P.4
Jeyasekharan, A.D.5
Venkitaraman, A.R.6
-
7
-
-
22544466685
-
Genomic instability in laminopathy-based premature aging
-
Liu B, Wang J, Chan KM, Tjia WM, Deng W, Guan X et al. Genomic instability in laminopathy-based premature aging. Nat Med 2005; 11: 780-785.
-
(2005)
Nat Med
, vol.11
, pp. 780-785
-
-
Liu, B.1
Wang, J.2
Chan, K.M.3
Tjia, W.M.4
Deng, W.5
Guan, X.6
-
8
-
-
79954626173
-
Recapitulation of premature ageing with iPSCs from Hutchinson-Gilford progeria syndrome
-
Liu GH, Barkho BZ, Ruiz S, Diep D, Qu J, Yang SL et al. Recapitulation of premature ageing with iPSCs from Hutchinson-Gilford progeria syndrome. Nature 2011; 472: 221-225.
-
(2011)
Nature
, vol.472
, pp. 221-225
-
-
Liu, G.H.1
Barkho, B.Z.2
Ruiz, S.3
Diep, D.4
Qu, J.5
Yang, S.L.6
-
9
-
-
84863613755
-
Multiple novel nesprin-1 and nesprin-2 variants act as versatile tissue-specific intracellular scaffolds
-
Rajgor D, Mellad JA, Autore F, Zhang Q, Shanahan CM. Multiple novel nesprin-1 and nesprin-2 variants act as versatile tissue-specific intracellular scaffolds. PLoS One 2012; 7: e40098.
-
(2012)
PLoS One
, vol.7
, pp. e40098
-
-
Rajgor, D.1
Mellad, J.A.2
Autore, F.3
Zhang, Q.4
Shanahan, C.M.5
-
10
-
-
74049100497
-
Novel nuclear nesprin-2 variants tether active extracellular signal-regulated MAPK1 and MAPK2 at promyelocytic leukemia protein nuclear bodies and act to regulate smooth muscle cell proliferation
-
Warren DT, Tajsic T, Mellad JA, Searles R, Zhang Q, Shanahan CM. Novel nuclear nesprin-2 variants tether active extracellular signal-regulated MAPK1 and MAPK2 at promyelocytic leukemia protein nuclear bodies and act to regulate smooth muscle cell proliferation. J Biol Chem 2010; 285: 1311-1320.
-
(2010)
J Biol Chem
, vol.285
, pp. 1311-1320
-
-
Warren, D.T.1
Tajsic, T.2
Mellad, J.A.3
Searles, R.4
Zhang, Q.5
Shanahan, C.M.6
-
11
-
-
33847066413
-
Extracellular signal-related kinase positively regulates ataxia telangiectasia mutated, homologous recombination repair, and the DNA damage response
-
Golding SE, Rosenberg E, Neill S, Dent P, Povirk LF, Valerie K. Extracellular signal-related kinase positively regulates ataxia telangiectasia mutated, homologous recombination repair, and the DNA damage response. Cancer Res 2007; 67: 1046-1053.
-
(2007)
Cancer Res
, vol.67
, pp. 1046-1053
-
-
Golding, S.E.1
Rosenberg, E.2
Neill, S.3
Dent, P.4
Povirk, L.F.5
Valerie, K.6
-
12
-
-
33644522087
-
ERK activity facilitates activation of the S-phase DNA damage checkpoint by modulating ATR function
-
Wu D, Chen B, Parihar K, He L, Fan C, Zhang J et al. ERK activity facilitates activation of the S-phase DNA damage checkpoint by modulating ATR function. Oncogene 2006; 25: 1153-1164.
-
(2006)
Oncogene
, vol.25
, pp. 1153-1164
-
-
Wu, D.1
Chen, B.2
Parihar, K.3
He, L.4
Fan, C.5
Zhang, J.6
-
13
-
-
33847377085
-
Evidence for the receipt of DNA damage stimuli by PML nuclear domains
-
Varadaraj A, Dovey CL, Laredj L, Ferguson B, Alexander CE, Lubben N et al. Evidence for the receipt of DNA damage stimuli by PML nuclear domains. J Pathol 2007; 211: 471-480.
-
(2007)
J Pathol
, vol.211
, pp. 471-480
-
-
Varadaraj, A.1
Dovey, C.L.2
Laredj, L.3
Ferguson, B.4
Alexander, C.E.5
Lubben, N.6
-
14
-
-
3242726103
-
PML regulates p53 stability by sequestering Mdm2 to the nucleolus
-
Bernardi R, Scaglioni PP, Bergmann S, Horn HF, Vousden KH, Pandolfi PP. PML regulates p53 stability by sequestering Mdm2 to the nucleolus. Nat Cell Biol 2004; 6: 665-672.
-
(2004)
Nat Cell Biol
, vol.6
, pp. 665-672
-
-
Bernardi, R.1
Scaglioni, P.P.2
Bergmann, S.3
Horn, H.F.4
Vousden, K.H.5
Pandolfi, P.P.6
-
15
-
-
0142106346
-
Cellular stress and DNA damage invoke temporally distinct Mdm2, p53 and PML complexes and damage-specific nuclear relocalization
-
Kurki S, Latonen L, Laiho M. Cellular stress and DNA damage invoke temporally distinct Mdm2, p53 and PML complexes and damage-specific nuclear relocalization. J Cell Sci 2003; 116: 3917-3925.
-
(2003)
J Cell Sci
, vol.116
, pp. 3917-3925
-
-
Kurki, S.1
Latonen, L.2
Laiho, M.3
-
16
-
-
77955655466
-
Both ERK1 and ERK2 kinases promote G2/M arrest in etoposide-treated MCF7 cells by facilitating ATM activation
-
Wei F, Xie Y, Tao L, Tang D. Both ERK1 and ERK2 kinases promote G2/M arrest in etoposide-treated MCF7 cells by facilitating ATM activation. Cell Signal 2010; 22: 1783-1789.
-
(2010)
Cell Signal
, vol.22
, pp. 1783-1789
-
-
Wei, F.1
Xie, Y.2
Tao, L.3
Tang, D.4
-
17
-
-
32044457898
-
A mechanism of AP-1 suppression through interaction of c-Fos with lamin A/C
-
Ivorra C, Kubicek M, Gonzalez JM, Sanz-Gonzalez SM, Alvarez-Barrientos A, O'Connor JE et al. A mechanism of AP-1 suppression through interaction of c-Fos with lamin A/C. Genes Dev 2006; 20: 307-320.
-
(2006)
Genes Dev
, vol.20
, pp. 307-320
-
-
Ivorra, C.1
Kubicek, M.2
Gonzalez, J.M.3
Sanz-Gonzalez, S.M.4
Alvarez-Barrientos, A.5
O'Connor, J.E.6
-
18
-
-
84863511156
-
Trajectories and nuclear arrangement of PML bodies are influenced by A-type lamin deficiency
-
Stixova L, Matula P, Kozubek S, Gombitova A, Cmarko D, Raska I et al. Trajectories and nuclear arrangement of PML bodies are influenced by A-type lamin deficiency. Biol Cell 2012; 104: 418-432.
-
(2012)
Biol Cell
, vol.104
, pp. 418-432
-
-
Stixova, L.1
Matula, P.2
Kozubek, S.3
Gombitova, A.4
Cmarko, D.5
Raska, I.6
-
19
-
-
79961083402
-
Histone H4 lysine 16 hypoacetylation is associated with defective DNA repair and premature senescence in Zmpste24-deficient mice
-
Krishnan V, Chow MZ, Wang Z, Zhang L, Liu B, Liu X et al. Histone H4 lysine 16 hypoacetylation is associated with defective DNA repair and premature senescence in Zmpste24-deficient mice. Proc Natl Acad Sci USA 2011; 108: 12325-12330.
-
(2011)
Proc Natl Acad Sci USA
, vol.108
, pp. 12325-12330
-
-
Krishnan, V.1
Chow, M.Z.2
Wang, Z.3
Zhang, L.4
Liu, B.5
Liu, X.6
-
20
-
-
84901844237
-
Mechanisms controlling the smooth muscle cell death in progeria via down-regulation of poly(ADP-ribose) polymerase 1
-
Zhang H, Xiong ZM, Cao K. Mechanisms controlling the smooth muscle cell death in progeria via down-regulation of poly(ADP-ribose) polymerase 1. Proc Natl Acad Sci USA 2014; 111: E2261-E2270.
-
(2014)
Proc Natl Acad Sci USA
, vol.111
, pp. E2261-E2270
-
-
Zhang, H.1
Xiong, Z.M.2
Cao, K.3
-
21
-
-
58149186768
-
Fast regulation of AP-1 activity through interaction of lamin A/C, ERK1/2, and c-Fos at the nuclear envelope
-
Gonzalez JM, Navarro-Puche A, Casar B, Crespo P, Andres V. Fast regulation of AP-1 activity through interaction of lamin A/C, ERK1/2, and c-Fos at the nuclear envelope. J Cell Biol 2008; 183: 653-666.
-
(2008)
J Cell Biol
, vol.183
, pp. 653-666
-
-
Gonzalez, J.M.1
Navarro-Puche, A.2
Casar, B.3
Crespo, P.4
Andres, V.5
-
22
-
-
21844432667
-
Lamin A/Cdependent localization of Nesprin-2, a giant scaffolder at the nuclear envelope
-
Libotte T, Zaim H, Abraham S, Padmakumar VC, Schneider M, Lu W et al. Lamin A/Cdependent localization of Nesprin-2, a giant scaffolder at the nuclear envelope. Mol Biol Cell 2005; 16: 3411-3424.
-
(2005)
Mol Biol Cell
, vol.16
, pp. 3411-3424
-
-
Libotte, T.1
Zaim, H.2
Abraham, S.3
Padmakumar, V.C.4
Schneider, M.5
Lu, W.6
-
23
-
-
84882573661
-
Mutations in LMNA modulate the lamin A-Nesprin-2 interaction and cause LINC complex alterations
-
Yang L, Munck M, Swaminathan K, Kapinos LE, Noegel AA, Neumann S. Mutations in LMNA modulate the lamin A-Nesprin-2 interaction and cause LINC complex alterations. PLoS One 2013; 8: e71850.
-
(2013)
PLoS One
, vol.8
, pp. e71850
-
-
Yang, L.1
Munck, M.2
Swaminathan, K.3
Kapinos, L.E.4
Noegel, A.A.5
Neumann, S.6
-
24
-
-
4644351274
-
PML nuclear bodies: Dynamic sensors of DNA damage and cellular stress
-
Dellaire G, Bazett-Jones DP. PML nuclear bodies: dynamic sensors of DNA damage and cellular stress. Bioessays 2004; 26: 963-977.
-
(2004)
Bioessays
, vol.26
, pp. 963-977
-
-
Dellaire, G.1
Bazett-Jones, D.P.2
-
25
-
-
0037665234
-
ATR kinase activity regulates the intranuclear translocation of ATR and RPA following ionizing radiation
-
Barr SM, Leung CG, Chang EE, Cimprich KA. ATR kinase activity regulates the intranuclear translocation of ATR and RPA following ionizing radiation. Curr Biol 2003; 13: 1047-1051.
-
(2003)
Curr Biol
, vol.13
, pp. 1047-1051
-
-
Barr, S.M.1
Leung, C.G.2
Chang, E.E.3
Cimprich, K.A.4
-
26
-
-
0037979238
-
PML colocalizes with and stabilizes the DNA damage response protein TopBP1
-
Xu ZX, Timanova-Atanasova A, Zhao RX, Chang KS. PML colocalizes with and stabilizes the DNA damage response protein TopBP1. Mol Cell Biol 2003; 23: 4247-4256.
-
(2003)
Mol Cell Biol
, vol.23
, pp. 4247-4256
-
-
Xu, Z.X.1
Timanova-Atanasova, A.2
Zhao, R.X.3
Chang, K.S.4
-
27
-
-
0034749425
-
DNA damage-dependent nuclear dynamics of the Mre11 complex
-
Mirzoeva OK, Petrini JH. DNA damage-dependent nuclear dynamics of the Mre11 complex. Mol Cell Biol 2001; 21: 281-288.
-
(2001)
Mol Cell Biol
, vol.21
, pp. 281-288
-
-
Mirzoeva, O.K.1
Petrini, J.H.2
-
28
-
-
84879685969
-
BMK1 is involved in the regulation of p53 through disrupting the PML-MDM2 interaction
-
Yang Q, Liao L, Deng X, Chen R, Gray NS, Yates 3rd JR et al. BMK1 is involved in the regulation of p53 through disrupting the PML-MDM2 interaction. Oncogene 2013; 32: 3156-3164.
-
(2013)
Oncogene
, vol.32
, pp. 3156-3164
-
-
Yang, Q.1
Liao, L.2
Deng, X.3
Chen, R.4
Gray, N.S.5
Yates, J.R.6
-
29
-
-
84899145875
-
The tumor suppressor PML specifically accumulates at RPA/Rad51-containing DNA damage repair foci but is nonessential for DNA damage-induced fibroblast senescence
-
Munch S, Weidtkamp-Peters S, Klement K, Grigaravicius P, Monajembashi S, Salomoni P et al. The tumor suppressor PML specifically accumulates at RPA/Rad51-containing DNA damage repair foci but is nonessential for DNA damage-induced fibroblast senescence. Mol Cell Biol 2014; 34: 1733-1746.
-
(2014)
Mol Cell Biol
, vol.34
, pp. 1733-1746
-
-
Munch, S.1
Weidtkamp-Peters, S.2
Klement, K.3
Grigaravicius, P.4
Monajembashi, S.5
Salomoni, P.6
-
30
-
-
0037066686
-
ERK activation mediates cell cycle arrest and apoptosis after DNA damage independently of p53
-
Tang D, Wu D, Hirao A, Lahti JM, Liu L, Mazza B et al. ERK activation mediates cell cycle arrest and apoptosis after DNA damage independently of p53. J Biol Chem 2002; 277: 12710-12717.
-
(2002)
J Biol Chem
, vol.277
, pp. 12710-12717
-
-
Tang, D.1
Wu, D.2
Hirao, A.3
Lahti, J.M.4
Liu, L.5
Mazza, B.6
-
31
-
-
84877094603
-
Large-scale modelling of the divergent spectrin repeats in nesprins: Giant modular proteins
-
Autore F, Pfuhl M, Quan X, Williams A, Roberts RG, Shanahan CM et al. Large-scale modelling of the divergent spectrin repeats in nesprins: giant modular proteins. PLoS One 2013; 8: e63633.
-
(2013)
PLoS One
, vol.8
, pp. e63633
-
-
Autore, F.1
Pfuhl, M.2
Quan, X.3
Williams, A.4
Roberts, R.G.5
Shanahan, C.M.6
-
32
-
-
77955661779
-
Stabilization of the spectrin-like domains of nesprin-1alpha by the evolutionarily conserved "adaptive" domain
-
Zhong Z, Chang SA, Kalinowski A, Wilson KL, Dahl KN. Stabilization of the spectrin-like domains of nesprin-1alpha by the evolutionarily conserved "adaptive" domain. Cell Mol Bioeng 2010; 3: 139-150.
-
(2010)
Cell Mol Bioeng
, vol.3
, pp. 139-150
-
-
Zhong, Z.1
Chang, S.A.2
Kalinowski, A.3
Wilson, K.L.4
Dahl, K.N.5
-
33
-
-
33751294581
-
The role of scaffold proteins in MEK/ERK signalling
-
Sacks DB. The role of scaffold proteins in MEK/ERK signalling. Biochem Soc Trans 2006; 34: 833-836.
-
(2006)
Biochem Soc Trans
, vol.34
, pp. 833-836
-
-
Sacks, D.B.1
-
35
-
-
0032508538
-
MP1: A MEK binding partner that enhances enzymatic activation of the MAP kinase cascade
-
Schaeffer HJ, Catling AD, Eblen ST, Collier LS, Krauss A, Weber MJ. MP1: a MEK binding partner that enhances enzymatic activation of the MAP kinase cascade. Science 1998; 281: 1668-1671.
-
(1998)
Science
, vol.281
, pp. 1668-1671
-
-
Schaeffer, H.J.1
Catling, A.D.2
Eblen, S.T.3
Collier, L.S.4
Krauss, A.5
Weber, M.J.6
-
36
-
-
0033598796
-
Medial localization of mineralization-regulating proteins in association with Monckeberg's sclerosis: Evidence for smooth muscle cell-mediated vascular calcification
-
Shanahan CM, Cary NR, Salisbury JR, Proudfoot D, Weissberg PL, Edmonds ME. Medial localization of mineralization-regulating proteins in association with Monckeberg's sclerosis: evidence for smooth muscle cell-mediated vascular calcification. Circulation 1999; 100: 2168-2176.
-
(1999)
Circulation
, vol.100
, pp. 2168-2176
-
-
Shanahan, C.M.1
Cary, N.R.2
Salisbury, J.R.3
Proudfoot, D.4
Weissberg, P.L.5
Edmonds, M.E.6
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