-
1
-
-
35748935532
-
Nesprin-1 and -2 are involved in the pathogenesis of Emery Dreifuss muscular dystrophy and are critical for nuclear envelope integrity
-
[1] Zhang, Q., Bethmann, C., Worth, N.F., Davies, J.D., Wasner, C., Feuer, A., Ragnauth, C.D., Yi, Q., Mellad, J.A., Warren, D.T., Wheeler, M.A., Ellis, J.A., Skepper, J.N., Vorgerd, M., Schlotter-Weigel, B., Weissberg, P.L., Roberts, R.G., Wehnert, M., Shanahan, C.M., Nesprin-1 and -2 are involved in the pathogenesis of Emery Dreifuss muscular dystrophy and are critical for nuclear envelope integrity. Hum. Mol. Genet. 16 (2007), 2816–2833.
-
(2007)
Hum. Mol. Genet.
, vol.16
, pp. 2816-2833
-
-
Zhang, Q.1
Bethmann, C.2
Worth, N.F.3
Davies, J.D.4
Wasner, C.5
Feuer, A.6
Ragnauth, C.D.7
Yi, Q.8
Mellad, J.A.9
Warren, D.T.10
Wheeler, M.A.11
Ellis, J.A.12
Skepper, J.N.13
Vorgerd, M.14
Schlotter-Weigel, B.15
Weissberg, P.L.16
Roberts, R.G.17
Wehnert, M.18
Shanahan, C.M.19
-
2
-
-
81855220949
-
Nesprin-3: a versatile connector between the nucleus and the cytoskeleton
-
[2] Ketema, M., Sonnenberg, A., Nesprin-3: a versatile connector between the nucleus and the cytoskeleton. Biochem. Soc. Trans. 39 (2011), 1719–1724.
-
(2011)
Biochem. Soc. Trans.
, vol.39
, pp. 1719-1724
-
-
Ketema, M.1
Sonnenberg, A.2
-
3
-
-
60549099949
-
Nesprin 4 is an outer nuclear membrane protein that can induce kinesin-mediated cell polarization
-
[3] Roux, K.J., Crisp, M.L., Liu, Q., Kim, D., Kozlov, S., Stewart, C.L., Burke, B., Nesprin 4 is an outer nuclear membrane protein that can induce kinesin-mediated cell polarization. Proc. Natl. Acad. Sci. USA 106 (2009), 2194–2199.
-
(2009)
Proc. Natl. Acad. Sci. USA
, vol.106
, pp. 2194-2199
-
-
Roux, K.J.1
Crisp, M.L.2
Liu, Q.3
Kim, D.4
Kozlov, S.5
Stewart, C.L.6
Burke, B.7
-
4
-
-
46749099446
-
Nesprin-2 Giant (NUANCE) maintains nuclear envelope architecture and composition in skin
-
[4] Luke, Y., Zaim, H., Karakesisoglou, I., Jaeger, V.M., Sellin, L., Lu, W., Schneider, M., Neumann, S., Beijer, A., Munck, M., Padmakumar, V.C., Gloy, J., Walz, G., Noegel, A.A., Nesprin-2 Giant (NUANCE) maintains nuclear envelope architecture and composition in skin. J. Cell Sci. 121 (2008), 1887–1898.
-
(2008)
J. Cell Sci.
, vol.121
, pp. 1887-1898
-
-
Luke, Y.1
Zaim, H.2
Karakesisoglou, I.3
Jaeger, V.M.4
Sellin, L.5
Lu, W.6
Schneider, M.7
Neumann, S.8
Beijer, A.9
Munck, M.10
Padmakumar, V.C.11
Gloy, J.12
Walz, G.13
Noegel, A.A.14
-
5
-
-
84863613755
-
Multiple novel nesprin-1 and nesprin-2 variants act as versatile tissue-specific intracellular scaffolds
-
[5] Rajgor, D., Mellad, J.A., Autore, F., Zhang, Q., Shanahan, C.M., Multiple novel nesprin-1 and nesprin-2 variants act as versatile tissue-specific intracellular scaffolds. PLoS One, 7, 2012, e40098.
-
(2012)
PLoS One
, vol.7
, pp. e40098
-
-
Rajgor, D.1
Mellad, J.A.2
Autore, F.3
Zhang, Q.4
Shanahan, C.M.5
-
6
-
-
14944383270
-
Nesprin-2 is a multi-isomeric protein that binds lamin and emerin at the nuclear envelope and forms a subcellular network in skeletal muscle
-
[6] Zhang, Q., Ragnauth, C.D., Skepper, J.N., Worth, N.F., Warren, D.T., Roberts, R.G., Weissberg, P.L., Ellis, J.A., Shanahan, C.M., Nesprin-2 is a multi-isomeric protein that binds lamin and emerin at the nuclear envelope and forms a subcellular network in skeletal muscle. J. Cell Sci. 118 (2005), 673–687.
-
(2005)
J. Cell Sci.
, vol.118
, pp. 673-687
-
-
Zhang, Q.1
Ragnauth, C.D.2
Skepper, J.N.3
Worth, N.F.4
Warren, D.T.5
Roberts, R.G.6
Weissberg, P.L.7
Ellis, J.A.8
Shanahan, C.M.9
-
7
-
-
1842850780
-
Enaptin, a giant actin-binding protein, is an element of the nuclear membrane and the actin cytoskeleton
-
[7] Padmakumar, V.C., Abraham, S., Braune, S., Noegel, A.A., Tunggal, B., Karakesisoglou, I., Korenbaum, E., Enaptin, a giant actin-binding protein, is an element of the nuclear membrane and the actin cytoskeleton. Exp. Cell Res. 295 (2004), 330–339.
-
(2004)
Exp. Cell Res.
, vol.295
, pp. 330-339
-
-
Padmakumar, V.C.1
Abraham, S.2
Braune, S.3
Noegel, A.A.4
Tunggal, B.5
Karakesisoglou, I.6
Korenbaum, E.7
-
8
-
-
34547174713
-
Distinct functional domains in nesprin-1alpha and nesprin-2beta bind directly to emerin and both interactions are disrupted in X-linked Emery-Dreifuss muscular dystrophy
-
[8] Wheeler, M.A., Davies, J.D., Zhang, Q., Emerson, L.J., Hunt, J., Shanahan, C.M., Ellis, J.A., Distinct functional domains in nesprin-1alpha and nesprin-2beta bind directly to emerin and both interactions are disrupted in X-linked Emery-Dreifuss muscular dystrophy. Exp. Cell Res. 313 (2007), 2845–2857.
-
(2007)
Exp. Cell Res.
, vol.313
, pp. 2845-2857
-
-
Wheeler, M.A.1
Davies, J.D.2
Zhang, Q.3
Emerson, L.J.4
Hunt, J.5
Shanahan, C.M.6
Ellis, J.A.7
-
9
-
-
84867055836
-
Structural insights into SUN-KASH complexes across the nuclear envelope
-
[9] Wang, W., Shi, Z., Jiao, S., Chen, C., Wang, H., Liu, G., Wang, Q., Zhao, Y., Greene, M.I., Zhou, Z., Structural insights into SUN-KASH complexes across the nuclear envelope. Cell Res. 22 (2012), 1440–1452.
-
(2012)
Cell Res.
, vol.22
, pp. 1440-1452
-
-
Wang, W.1
Shi, Z.2
Jiao, S.3
Chen, C.4
Wang, H.5
Liu, G.6
Wang, Q.7
Zhao, Y.8
Greene, M.I.9
Zhou, Z.10
-
10
-
-
29944445023
-
Coupling of the nucleus and cytoplasm: role of the LINC complex
-
[10] Crisp, M., Liu, Q., Roux, K., Rattner, J.B., Shanahan, C., Burke, B., Stahl, P.D., Hodzic, D., Coupling of the nucleus and cytoplasm: role of the LINC complex. J. Cell Biol. 172 (2006), 41–53.
-
(2006)
J. Cell Biol.
, vol.172
, pp. 41-53
-
-
Crisp, M.1
Liu, Q.2
Roux, K.3
Rattner, J.B.4
Shanahan, C.5
Burke, B.6
Stahl, P.D.7
Hodzic, D.8
-
11
-
-
33646555082
-
SUN1 interacts with nuclear lamin A and cytoplasmic nesprins to provide a physical connection between the nuclear lamina and the cytoskeleton
-
[11] Haque, F., Lloyd, D.J., Smallwood, D.T., Dent, C.L., Shanahan, C.M., Fry, A.M., Trembath, R.C., Shackleton, S., SUN1 interacts with nuclear lamin A and cytoplasmic nesprins to provide a physical connection between the nuclear lamina and the cytoskeleton. Mol. Cell Biol. 26 (2006), 3738–3751.
-
(2006)
Mol. Cell Biol.
, vol.26
, pp. 3738-3751
-
-
Haque, F.1
Lloyd, D.J.2
Smallwood, D.T.3
Dent, C.L.4
Shanahan, C.M.5
Fry, A.M.6
Trembath, R.C.7
Shackleton, S.8
-
12
-
-
77449109551
-
Mammalian SUN protein interaction networks at the inner nuclear membrane and their role in laminopathy disease processes
-
[12] Haque, F., Mazzeo, D., Patel, J.T., Smallwood, D.T., Ellis, J.A., Shanahan, C.M., Shackleton, S., Mammalian SUN protein interaction networks at the inner nuclear membrane and their role in laminopathy disease processes. J. Biol. Chem. 285 (2010), 3487–3498.
-
(2010)
J. Biol. Chem.
, vol.285
, pp. 3487-3498
-
-
Haque, F.1
Mazzeo, D.2
Patel, J.T.3
Smallwood, D.T.4
Ellis, J.A.5
Shanahan, C.M.6
Shackleton, S.7
-
13
-
-
84901814722
-
Mammalian microtubule P-body dynamics are mediated by nesprin-1
-
[13] Rajgor, D., Mellad, J.A., Soong, D., Rattner, J.B., Fritzler, M.J., Shanahan, C.M., Mammalian microtubule P-body dynamics are mediated by nesprin-1. J. Cell Biol. 205 (2014), 457–475.
-
(2014)
J. Cell Biol.
, vol.205
, pp. 457-475
-
-
Rajgor, D.1
Mellad, J.A.2
Soong, D.3
Rattner, J.B.4
Fritzler, M.J.5
Shanahan, C.M.6
-
14
-
-
74049100497
-
Novel nuclear nesprin-2 variants tether active extracellular signal-regulated MAPK1 and MAPK2 at promyelocytic leukemia protein nuclear bodies and act to regulate smooth muscle cell proliferation
-
[14] Warren, D.T., Tajsic, T., Mellad, J.A., Searles, R., Zhang, Q., Shanahan, C.M., Novel nuclear nesprin-2 variants tether active extracellular signal-regulated MAPK1 and MAPK2 at promyelocytic leukemia protein nuclear bodies and act to regulate smooth muscle cell proliferation. J. Biol. Chem. 285 (2010), 1311–1320.
-
(2010)
J. Biol. Chem.
, vol.285
, pp. 1311-1320
-
-
Warren, D.T.1
Tajsic, T.2
Mellad, J.A.3
Searles, R.4
Zhang, Q.5
Shanahan, C.M.6
-
15
-
-
80052037833
-
Nesprin-2 epsilon: a novel nesprin isoform expressed in human ovary and Ntera-2 cells
-
[15] Lam le, T., Bohm, S.V., Roberts, R.G., Morris, G.E., Nesprin-2 epsilon: a novel nesprin isoform expressed in human ovary and Ntera-2 cells. Biochem. Biophys. Res. Commun. 412 (2011), 291–295.
-
(2011)
Biochem. Biophys. Res. Commun.
, vol.412
, pp. 291-295
-
-
Lam le, T.1
Bohm, S.V.2
Roberts, R.G.3
Morris, G.E.4
-
16
-
-
84877094603
-
Large-scale modelling of the divergent spectrin repeats in nesprins: giant modular proteins
-
[16] Autore, F., Pfuhl, M., Quan, X., Williams, A., Roberts, R.G., Shanahan, C.M., Fraternali, F., Large-scale modelling of the divergent spectrin repeats in nesprins: giant modular proteins. PLoS One, 8, 2013, e63633.
-
(2013)
PLoS One
, vol.8
, pp. e63633
-
-
Autore, F.1
Pfuhl, M.2
Quan, X.3
Williams, A.4
Roberts, R.G.5
Shanahan, C.M.6
Fraternali, F.7
-
17
-
-
69549122198
-
Nesprin-2 interacts with meckelin and mediates ciliogenesis via remodelling of the actin cytoskeleton
-
[17] Dawe, H.R., Adams, M., Wheway, G., Szymanska, K., Logan, C.V., Noegel, A.A., Gull, K., Johnson, C.A., Nesprin-2 interacts with meckelin and mediates ciliogenesis via remodelling of the actin cytoskeleton. J. Cell Sci. 122 (2009), 2716–2726.
-
(2009)
J. Cell Sci.
, vol.122
, pp. 2716-2726
-
-
Dawe, H.R.1
Adams, M.2
Wheway, G.3
Szymanska, K.4
Logan, C.V.5
Noegel, A.A.6
Gull, K.7
Johnson, C.A.8
-
18
-
-
8444223093
-
Wnt signals across the plasma membrane to activate the beta-catenin pathway by forming oligomers containing its receptors, Frizzled and LRP
-
[18] Cong, F., Schweizer, L., Varmus, H., Wnt signals across the plasma membrane to activate the beta-catenin pathway by forming oligomers containing its receptors, Frizzled and LRP. Development 131 (2004), 5103–5115.
-
(2004)
Development
, vol.131
, pp. 5103-5115
-
-
Cong, F.1
Schweizer, L.2
Varmus, H.3
-
19
-
-
1542297761
-
Nuclear-cytoplasmic shuttling of Axin regulates subcellular localization of beta-catenin
-
[19] Cong, F., Varmus, H., Nuclear-cytoplasmic shuttling of Axin regulates subcellular localization of beta-catenin. Proc. Natl. Acad. Sci. USA 101 (2004), 2882–2887.
-
(2004)
Proc. Natl. Acad. Sci. USA
, vol.101
, pp. 2882-2887
-
-
Cong, F.1
Varmus, H.2
-
20
-
-
1242272084
-
Nucleo-cytoplasmic shuttling of Axin, a negative regulator of the Wnt-beta-catenin Pathway
-
[20] Wiechens, N., Heinle, K., Englmeier, L., Schohl, A., Fagotto, F., Nucleo-cytoplasmic shuttling of Axin, a negative regulator of the Wnt-beta-catenin Pathway. J. Biol. Chem. 279 (2004), 5263–5267.
-
(2004)
J. Biol. Chem.
, vol.279
, pp. 5263-5267
-
-
Wiechens, N.1
Heinle, K.2
Englmeier, L.3
Schohl, A.4
Fagotto, F.5
-
21
-
-
84984670213
-
The hydrophobic rich N- and C-terminal tails of beta-catenin facilitate nuclear import of beta-catenin
-
[21] Sharma, M., Jamieson, C., Lui, C., Henderson, B.R., The hydrophobic rich N- and C-terminal tails of beta-catenin facilitate nuclear import of beta-catenin. J. Biol. Chem., 2014.
-
(2014)
J. Biol. Chem.
-
-
Sharma, M.1
Jamieson, C.2
Lui, C.3
Henderson, B.R.4
-
22
-
-
78049402790
-
Nesprin-2 interacts with {alpha}-catenin and regulates Wnt signaling at the nuclear envelope
-
[22] Neumann, S., Schneider, M., Daugherty, R.L., Gottardi, C.J., Eming, S.A., Beijer, A., Noegel, A.A., Karakesisoglou, I., Nesprin-2 interacts with {alpha}-catenin and regulates Wnt signaling at the nuclear envelope. J. Biol. Chem. 285 (2010), 34932–34938.
-
(2010)
J. Biol. Chem.
, vol.285
, pp. 34932-34938
-
-
Neumann, S.1
Schneider, M.2
Daugherty, R.L.3
Gottardi, C.J.4
Eming, S.A.5
Beijer, A.6
Noegel, A.A.7
Karakesisoglou, I.8
-
23
-
-
33746500691
-
The inner nuclear membrane protein emerin regulates beta-catenin activity by restricting its accumulation in the nucleus
-
[23] Markiewicz, E., Tilgner, K., Barker, N., van de Wetering, M., Clevers, H., Dorobek, M., Hausmanowa-Petrusewicz, I., Ramaekers, F.C., Broers, J.L., Blankesteijn, W.M., Salpingidou, G., Wilson, R.G., Ellis, J.A., Hutchison, C.J., The inner nuclear membrane protein emerin regulates beta-catenin activity by restricting its accumulation in the nucleus. EMBO J. 25 (2006), 3275–3285.
-
(2006)
EMBO J.
, vol.25
, pp. 3275-3285
-
-
Markiewicz, E.1
Tilgner, K.2
Barker, N.3
van de Wetering, M.4
Clevers, H.5
Dorobek, M.6
Hausmanowa-Petrusewicz, I.7
Ramaekers, F.C.8
Broers, J.L.9
Blankesteijn, W.M.10
Salpingidou, G.11
Wilson, R.G.12
Ellis, J.A.13
Hutchison, C.J.14
-
24
-
-
0035694555
-
Nesprins: a novel family of spectrin-repeat-containing proteins that localize to the nuclear membrane in multiple tissues
-
[24] Zhang, Q., Skepper, J.N., Yang, F., Davies, J.D., Hegyi, L., Roberts, R.G., Weissberg, P.L., Ellis, J.A., Shanahan, C.M., Nesprins: a novel family of spectrin-repeat-containing proteins that localize to the nuclear membrane in multiple tissues. J. Cell Sci. 114 (2001), 4485–4498.
-
(2001)
J. Cell Sci.
, vol.114
, pp. 4485-4498
-
-
Zhang, Q.1
Skepper, J.N.2
Yang, F.3
Davies, J.D.4
Hegyi, L.5
Roberts, R.G.6
Weissberg, P.L.7
Ellis, J.A.8
Shanahan, C.M.9
-
25
-
-
77953023624
-
Prelamin A acts to accelerate smooth muscle cell senescence and is a novel biomarker of human vascular aging
-
[25] Ragnauth, C.D., Warren, D.T., Liu, Y., McNair, R., Tajsic, T., Figg, N., Shroff, R., Skepper, J., Shanahan, C.M., Prelamin A acts to accelerate smooth muscle cell senescence and is a novel biomarker of human vascular aging. Circulation 121 (2010), 2200–2210.
-
(2010)
Circulation
, vol.121
, pp. 2200-2210
-
-
Ragnauth, C.D.1
Warren, D.T.2
Liu, Y.3
McNair, R.4
Tajsic, T.5
Figg, N.6
Shroff, R.7
Skepper, J.8
Shanahan, C.M.9
-
26
-
-
77149147397
-
Nesprins, but not sun proteins, switch isoforms at the nuclear envelope during muscle development
-
[26] Randles, K.N., Lam le, T., Sewry, C.A., Puckelwartz, M., Furling, D., Wehnert, M., McNally, E.M., Morris, G.E., Nesprins, but not sun proteins, switch isoforms at the nuclear envelope during muscle development. Dev. Dyn. 239 (2010), 998–1009.
-
(2010)
Dev. Dyn.
, vol.239
, pp. 998-1009
-
-
Randles, K.N.1
Lam le, T.2
Sewry, C.A.3
Puckelwartz, M.4
Furling, D.5
Wehnert, M.6
McNally, E.M.7
Morris, G.E.8
-
27
-
-
84939601097
-
Cell shape dependent regulation of nuclear morphology
-
[27] Chen, B., Co, C., Ho, C.C., Cell shape dependent regulation of nuclear morphology. Biomaterials 67 (2015), 129–136.
-
(2015)
Biomaterials
, vol.67
, pp. 129-136
-
-
Chen, B.1
Co, C.2
Ho, C.C.3
-
28
-
-
84857769496
-
Spatial coordination between cell and nuclear shape within micropatterned endothelial cells
-
[28] Versaevel, M., Grevesse, T., Gabriele, S., Spatial coordination between cell and nuclear shape within micropatterned endothelial cells. Nat. Commun., 3, 2012, 671.
-
(2012)
Nat. Commun.
, vol.3
, pp. 671
-
-
Versaevel, M.1
Grevesse, T.2
Gabriele, S.3
-
29
-
-
84899508418
-
Nesprins: tissue-specific expression of epsilon and other short isoforms
-
[29] Duong, N.T., Morris, G.E., Lam le, T., Zhang, Q., Sewry, C.A., Shanahan, C.M., Holt, I., Nesprins: tissue-specific expression of epsilon and other short isoforms. PLoS One, 9, 2014, e94380.
-
(2014)
PLoS One
, vol.9
, pp. e94380
-
-
Duong, N.T.1
Morris, G.E.2
Lam le, T.3
Zhang, Q.4
Sewry, C.A.5
Shanahan, C.M.6
Holt, I.7
-
30
-
-
80052961942
-
Increased expression of Syne1/nesprin-1 facilitates nuclear envelope structure changes in embryonic stem cell differentiation
-
[30] Smith, E.R., Zhang, X.Y., Capo-Chichi, C.D., Chen, X., Xu, X.X., Increased expression of Syne1/nesprin-1 facilitates nuclear envelope structure changes in embryonic stem cell differentiation. Dev. Dyn. 240 (2011), 2245–2255.
-
(2011)
Dev. Dyn.
, vol.240
, pp. 2245-2255
-
-
Smith, E.R.1
Zhang, X.Y.2
Capo-Chichi, C.D.3
Chen, X.4
Xu, X.X.5
-
31
-
-
84916232918
-
Nesprin-1 has key roles in the process of mesenchymal stem cell differentiation into cardiomyocyte-like cells in vivo and in vitro
-
[31] Yang, W., Zheng, H., Wang, Y., Lian, F., Hu, Z., Xue, S., Nesprin-1 has key roles in the process of mesenchymal stem cell differentiation into cardiomyocyte-like cells in vivo and in vitro. Mol. Med. Rep. 11 (2015), 133–142.
-
(2015)
Mol. Med. Rep.
, vol.11
, pp. 133-142
-
-
Yang, W.1
Zheng, H.2
Wang, Y.3
Lian, F.4
Hu, Z.5
Xue, S.6
-
32
-
-
84905483305
-
The Nesprin family member ANC-1 regulates synapse formation and axon termination by functioning in a pathway with RPM-1 and beta-Catenin
-
[32] Tulgren, E.D., Turgeon, S.M., Opperman, K.J., Grill, B., The Nesprin family member ANC-1 regulates synapse formation and axon termination by functioning in a pathway with RPM-1 and beta-Catenin. PLoS Genet., 10, 2014, e1004481.
-
(2014)
PLoS Genet.
, vol.10
, pp. e1004481
-
-
Tulgren, E.D.1
Turgeon, S.M.2
Opperman, K.J.3
Grill, B.4
|