Transcriptome evidence reveals enhanced autophagy-lysosomal function in centenarians

Genome Research

Volumn 28, Issue 11, 2018, Pages 1601-1610

  Wang, Xiao Fan ^h   Chen, Xiao Qiong ^a,b,d,f   Yu, Qin ^a,b,d,e,f   Liu, Yao Wen ^a,b,d,e,f   Yang, Li Qin ^a,b,d,f   He, Yong Han ^a,b,d,f   Kong, Qing Peng ^a,b,d,f  

^a KUNMING INSTITUTE OF ZOOLOGY   (China)

^b INSTITUTE OF GEOLOGY AND GEOPHYSICS   (China)

^c HAINAN MEDICAL UNIVERSITY   (China)

^d CHINESE UNIVERSITY OF HONG KONG   (Hong Kong)

^e UNIVERSITY OF CHINESE ACADEMY OF SCIENCES   (China)

^f Kunming Key Laboratory of Healthy Aging Molecular Mechanism Study   (China)

^g Prince of Wales Hospital   (Hong Kong)

^h DUKE UNIVERSITY MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ATG4D PROTEIN; ATP6V0C PROTEIN; BECLIN 1; CTSB PROTEIN; EIF4EBP1 PROTEIN; EPC1 PROTEIN; GALACTOSIDASE BETA 1; GSR PROTEIN; MYC PROTEIN; PEROXIREDOXIN 1; PHOSPHOINOSITIDE DEPENDENT PROTEIN KINASE 1; PROTEIN; SEQUESTOSOME 1; TRANSCRIPTOME; UNCLASSIFIED DRUG; WIPI1 PROTEIN; ATG4D PROTEIN, HUMAN; ATP6V0C PROTEIN, HUMAN; AUTOPHAGY RELATED PROTEIN; BECN1 PROTEIN, HUMAN; CATHEPSIN B; CTSB PROTEIN, HUMAN; CYSTEINE PROTEINASE; MEMBRANE PROTEIN; PROTON TRANSPORTING ADENOSINE TRIPHOSPHATE SYNTHASE; WIPI-1 PROTEIN, HUMAN;

ADULT; ANIMAL CELL; ARTICLE; AUTOPHAGY; CELL AGING; CELL PROLIFERATION; CONTROLLED STUDY; DOWN REGULATION; DROSOPHILA; FEMALE; GENDER BIAS; GENE OVEREXPRESSION; HUMAN; IMR-90 CELL LINE; LIFESPAN; LONGEVITY; LYSOSOME; MALE; MIDDLE AGED; NONHUMAN; PRIORITY JOURNAL; PROGENY; REAL TIME POLYMERASE CHAIN REACTION; RNA SEQUENCE; UPREGULATION; VERY ELDERLY; WESTERN BLOTTING; AGED; GENETICS; METABOLISM;

AGED; AGED, 80 AND OVER; AUTOPHAGY; AUTOPHAGY-RELATED PROTEINS; BECLIN-1; CATHEPSIN B; CYSTEINE ENDOPEPTIDASES; FEMALE; HUMANS; LONGEVITY; LYSOSOMES; MALE; MEMBRANE PROTEINS; MIDDLE AGED; TRANSCRIPTOME; VACUOLAR PROTON-TRANSLOCATING ATPASES;

EID: 85055904282     PISSN: 10889051     EISSN: 15495469     Source Type: Journal    
DOI: 10.1101/gr.220780.117     Document Type: Article

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