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Volumn 123, Issue 2, 2018, Pages 177-187

Enhancement strategies for cardiac regenerative cell therapy focus on adult stem cells

Author keywords

Adult stem cells; Cardiovascular disease; Cell therapy; Heart failure

Indexed keywords

LENTIVIRUS VECTOR;

EID: 85055081148     PISSN: 00097330     EISSN: 15244571     Source Type: Journal    
DOI: 10.1161/CIRCRESAHA.118.311207     Document Type: Article
Times cited : (19)

References (107)
  • 1
    • 85066418972 scopus 로고    scopus 로고
    • United States Code
    • United States Code. Supplement 5, Title 21: Food and Drugs. 2006:25–449. https://www.gpo.gov/fdsys/granule/USCODE-2011-title21/USCODE2011-title21-chap9.
    • (2006) Supplement 5, Title 21: Food and Drugs , pp. 25-449
  • 4
    • 85066415828 scopus 로고    scopus 로고
    • Guidance for industry: Regulation of human cells, tissues, and cellular and tissue-based products (HCT/PS)
    • Food and Drug Administration. Guidance for Industry: Regulation of Human Cells, Tissues, and Cellular and Tissue-Based Products (HCT/Ps). Small Entity Compliance Guide. 2007. https://www.fda.gov/downloads/biologicsbloodvaccines/guidancecomplianceregulatoryinformation/guid-ances/tissue/ucm062592.pdf.
    • (2007) Small Entity Compliance Guide
  • 5
    • 33750081777 scopus 로고    scopus 로고
    • FDA regulation of stem-cell-based therapies
    • Halme DG, Kessler DA. FDA regulation of stem-cell-based therapies. N Engl J Med. 2006;355:1730–1735. doi: 10.1056/NEJMhpr063086.
    • (2006) N Engl J Med , vol.355 , pp. 1730-1735
    • Halme, D.G.1    Kessler, D.A.2
  • 6
    • 84962516298 scopus 로고    scopus 로고
    • Empowering adult stem cells for myocardial regeneration V2.0: Success in small steps
    • Broughton KM, Sussman MA. Empowering adult stem cells for myocardial regeneration V2.0: success in small steps. Circ Res. 2016;118:867–880. doi: 10.1161/CIRCRESAHA.115.305227.
    • (2016) Circ Res , vol.118 , pp. 867-880
    • Broughton, K.M.1    Sussman, M.A.2
  • 8
  • 9
    • 84969376984 scopus 로고    scopus 로고
    • Executive summary: Heart disease and stroke statistics-2016 update: A report from the American Heart Association
    • Mozaffarian D, Benjamin EJ, Go AS, et al. Executive summary: heart disease and stroke statistics-2016 update: a report from the American Heart Association. Circulation. 2016;133(4):447–454.
    • (2016) Circulation , vol.133 , Issue.4 , pp. 447-454
    • Mozaffarian, D.1    Benjamin, E.J.2    Go, A.S.3
  • 10
    • 0025801813 scopus 로고
    • Cardiomyopathy of the aging human heart. Myocyte loss and reactive cellular hypertrophy
    • Olivetti G, Melissari M, Capasso JM, Anversa P. Cardiomyopathy of the aging human heart. Myocyte loss and reactive cellular hypertrophy. Circ Res. 1991;68:1560–1568.
    • (1991) Circ Res , vol.68 , pp. 1560-1568
    • Olivetti, G.1    Melissari, M.2    Capasso, J.M.3    Anversa, P.4
  • 11
    • 85047678791 scopus 로고
    • Reperfusion induced injury: Manifestations, mechanisms, and clinical relevance
    • Hearse DJ, Bolli R. Reperfusion induced injury: manifestations, mechanisms, and clinical relevance. Cardiovasc Res. 1992;26:101–108.
    • (1992) Cardiovasc Res , vol.26 , pp. 101-108
    • Hearse, D.J.1    Bolli, R.2
  • 14
    • 85021845590 scopus 로고    scopus 로고
    • Dedifferentiation, proliferation, and redifferentiation of adult mammalian cardiomyocytes after ischemic injury
    • Wang WE, Li L, Xia X, et al. Dedifferentiation, proliferation, and redifferentiation of adult mammalian cardiomyocytes after ischemic injury. Circulation. 2017;136:834–848. doi: 10.1161/CIRCULATIONAHA.116.024307.
    • (2017) Circulation , vol.136 , pp. 834-848
    • Wang, W.E.1    Li, L.2    Xia, X.3
  • 16
    • 84882759023 scopus 로고    scopus 로고
    • Adult c-kit(pos) cardiac stem cells are necessary and sufficient for functional cardiac regeneration and repair
    • Ellison GM, Vicinanza C, Smith AJ, et al. Adult c-kit(pos) cardiac stem cells are necessary and sufficient for functional cardiac regeneration and repair. Cell. 2013;154:827–842. doi: 10.1016/j.cell.2013.07.039.
    • (2013) Cell , vol.154 , pp. 827-842
    • Ellison, G.M.1    Vicinanza, C.2    Smith, A.J.3
  • 21
    • 84857838864 scopus 로고    scopus 로고
    • Harnessing the mesenchymal stem cell secretome for the treatment of cardiovascular disease
    • Ranganath SH, Levy O, Inamdar MS, Karp JM. Harnessing the mesenchymal stem cell secretome for the treatment of cardiovascular disease. Cell Stem Cell. 2012;10:244–258. doi: 10.1016/j.stem.2012.02.005.
    • (2012) Cell Stem Cell , vol.10 , pp. 244-258
    • Ranganath, S.H.1    Levy, O.2    Inamdar, M.S.3    Karp, J.M.4
  • 23
    • 84898841773 scopus 로고    scopus 로고
    • Autologous mesenchymal stem cells produce concordant improvements in regional function, tissue perfusion, and fibrotic burden when administered to patients undergoing coronary artery bypass grafting: The Prospective Randomized Study of Mesenchymal Stem Cell Therapy in Patients Undergoing Cardiac Surgery (PROMETHEUS) trial
    • Karantalis V, DiFede DL, Gerstenblith G, et al. Autologous mesenchymal stem cells produce concordant improvements in regional function, tissue perfusion, and fibrotic burden when administered to patients undergoing coronary artery bypass grafting: the Prospective Randomized Study of Mesenchymal Stem Cell Therapy in Patients Undergoing Cardiac Surgery (PROMETHEUS) trial. Circ Res. 2014;114:1302–1310. doi: 10.1161/CIRCRESAHA.114.303180.
    • (2014) Circ Res , vol.114 , pp. 1302-1310
    • Karantalis, V.1    DiFede, D.L.2    Gerstenblith, G.3
  • 24
    • 82255175382 scopus 로고    scopus 로고
    • Cardiac stem cells in patients with ischaemic cardiomyopathy (SCIPIO): Initial results of a randomised phase 1 trial
    • Bolli R, Chugh AR, D’Amario D, et al. Cardiac stem cells in patients with ischaemic cardiomyopathy (SCIPIO): initial results of a randomised phase 1 trial. Lancet. 2011;378:1847–1857. doi: 10.1016/S0140-6736(11)61590-0.
    • (2011) Lancet , vol.378 , pp. 1847-1857
    • Bolli, R.1    Chugh, A.R.2    D’Amario, D.3
  • 25
    • 84876405558 scopus 로고    scopus 로고
    • Effect of cardiac stem cells in patients with ischemic cardiomyopathy: Interim results of the SCIPIO trial up to 2 years after therapy
    • Bolli R, Chugh AR, D’Amario D, et al. Effect of cardiac stem cells in patients with ischemic cardiomyopathy: interim results of the SCIPIO trial up to 2 years after therapy. Circulation. 2012;126(23):2784.
    • (2012) Circulation , vol.126 , Issue.23 , pp. 2784
    • Bolli, R.1    Chugh, A.R.2    D’Amario, D.3
  • 27
    • 0038376000 scopus 로고    scopus 로고
    • Therapeutic stem and progenitor cell transplantation for organ vascularization and regeneration
    • Rafii S, Lyden D. Therapeutic stem and progenitor cell transplantation for organ vascularization and regeneration. Nat Med. 2003;9:702–712. doi: 10.1038/nm0603-702.
    • (2003) Nat Med , vol.9 , pp. 702-712
    • Rafii, S.1    Lyden, D.2
  • 29
    • 58149347238 scopus 로고    scopus 로고
    • Paracrine mechanisms in adult stem cell signaling and therapy
    • Gnecchi M, Zhang Z, Ni A, Dzau VJ. Paracrine mechanisms in adult stem cell signaling and therapy. Circ Res. 2008;103:1204–1219. doi: 10.1161/CIRCRESAHA.108.176826.
    • (2008) Circ Res , vol.103 , pp. 1204-1219
    • Gnecchi, M.1    Zhang, Z.2    Ni, A.3    Dzau, V.J.4
  • 32
    • 84872281137 scopus 로고    scopus 로고
    • Enhanced effect of combining human cardiac stem cells and bone marrow mesenchymal stem cells to reduce infarct size and to restore cardiac function after myocardial infarction
    • Williams AR, Hatzistergos KE, Addicott B, McCall F, Carvalho D, Suncion V, Morales AR, Da Silva J, Sussman MA, Heldman AW, Hare JM. Enhanced effect of combining human cardiac stem cells and bone marrow mesenchymal stem cells to reduce infarct size and to restore cardiac function after myocardial infarction. Circulation. 2013;127:213–223. doi: 10.1161/CIRCULATIONAHA.112.131110.
    • (2013) Circulation , vol.127 , pp. 213-223
    • Williams, A.R.1    Hatzistergos, K.E.2    Addicott, B.3    McCall, F.4    Carvalho, D.5    Suncion, V.6    Morales, A.R.7    Da Silva, J.8    Sussman, M.A.9    Heldman, A.W.10    Hare, J.M.11
  • 33
    • 84942457205 scopus 로고    scopus 로고
    • Synergistic effects of combined cell therapy for chronic ischemic cardiomyopathy
    • Karantalis V, Suncion-Loescher VY, Bagno L, et al. Synergistic effects of combined cell therapy for chronic ischemic cardiomyopathy. J Am Coll Cardiol. 2015;66:1990–1999. doi: 10.1016/j.jacc.2015.08.879.
    • (2015) J Am Coll Cardiol , vol.66 , pp. 1990-1999
    • Karantalis, V.1    Suncion-Loescher, V.Y.2    Bagno, L.3
  • 34
    • 85032689613 scopus 로고    scopus 로고
    • A combination of allogeneic stem cells promotes cardiac regeneration
    • Natsumeda M, Florea V, Rieger AC, et al. A combination of allogeneic stem cells promotes cardiac regeneration. J Am Coll Cardiol. 2017;70:2504–2515. doi: 10.1016/j.jacc.2017.09.036.
    • (2017) J Am Coll Cardiol , vol.70 , pp. 2504-2515
    • Natsumeda, M.1    Florea, V.2    Rieger, A.C.3
  • 35
    • 84928601892 scopus 로고    scopus 로고
    • Combined intramyocardial delivery of human pericytes and cardiac stem cells additively improves the healing of mouse infarcted hearts through stimulation of vascular and muscular repair
    • Avolio E, Meloni M, Spencer HL, et al. Combined intramyocardial delivery of human pericytes and cardiac stem cells additively improves the healing of mouse infarcted hearts through stimulation of vascular and muscular repair. Circ Res. 2015;116:e81–e94. doi: 10.1161/CIRCRESAHA.115.306146.
    • (2015) Circ Res , vol.116 , pp. e81-e94
    • Avolio, E.1    Meloni, M.2    Spencer, H.L.3
  • 37
    • 85066419542 scopus 로고    scopus 로고
    • CardioClusters: Harnessing the power of multi-lineage cardiac stem cells
    • Abstract
    • Monsanto MM, White KS, Wang J, Fisher K, Sussman MA. CardioClusters: harnessing the power of multi-lineage cardiac stem cells. Circulation. 2016;13A:A19532. Abstract.
    • (2016) Circulation , vol.13 A , pp. A19532
    • Monsanto, M.M.1    White, K.S.2    Wang, J.3    Fisher, K.4    Sussman, M.A.5
  • 39
    • 26844525184 scopus 로고    scopus 로고
    • Soluble factors released by endothelial progenitor cells promote migration of endothelial cells and cardiac resident progenitor cells
    • Urbich C, Aicher A, Heeschen C, Dernbach E, Hofmann WK, Zeiher AM, Dimmeler S. Soluble factors released by endothelial progenitor cells promote migration of endothelial cells and cardiac resident progenitor cells. J Mol Cell Cardiol. 2005;39:733–742. doi: 10.1016/j.yjmcc.2005.07.003.
    • (2005) J Mol Cell Cardiol , vol.39 , pp. 733-742
    • Urbich, C.1    Aicher, A.2    Heeschen, C.3    Dernbach, E.4    Hofmann, W.K.5    Zeiher, A.M.6    Dimmeler, S.7
  • 40
    • 73849142463 scopus 로고    scopus 로고
    • Preconditioning mesenchymal stem cells with transforming growth factor-alpha improves mesenchymal stem cell-mediated cardioprotection
    • Herrmann JL, Wang Y, Abarbanell AM, Weil BR, Tan J, Meldrum DR. Preconditioning mesenchymal stem cells with transforming growth factor-alpha improves mesenchymal stem cell-mediated cardioprotection. Shock. 2010;33:24–30. doi: 10.1097/SHK.0b013e3181b7d137.
    • (2010) Shock , vol.33 , pp. 24-30
    • Herrmann, J.L.1    Wang, Y.2    Abarbanell, A.M.3    Weil, B.R.4    Tan, J.5    Meldrum, D.R.6
  • 41
    • 39549105786 scopus 로고    scopus 로고
    • Pre-treatment of mesenchymal stem cells with a combination of growth factors enhances gap junction formation, cytoprotective effect on cardiomyocytes, and therapeutic efficacy for myocardial infarction
    • Hahn JY, Cho HJ, Kang HJ, Kim TS, Kim MH, Chung JH, Bae JW, Oh BH, Park YB, Kim HS. Pre-treatment of mesenchymal stem cells with a combination of growth factors enhances gap junction formation, cytoprotective effect on cardiomyocytes, and therapeutic efficacy for myocardial infarction. J Am Coll Cardiol. 2008;51:933–943. doi: 10.1016/j.jacc.2007.11.040.
    • (2008) J Am Coll Cardiol , vol.51 , pp. 933-943
    • Hahn, J.Y.1    Cho, H.J.2    Kang, H.J.3    Kim, T.S.4    Kim, M.H.5    Chung, J.H.6    Bae, J.W.7    Oh, B.H.8    Park, Y.B.9    Kim, H.S.10
  • 42
    • 78650973243 scopus 로고    scopus 로고
    • Growth factor preconditioning increases the function of diabetes-impaired mesenchymal stem cells
    • Khan M, Akhtar S, Mohsin S, N Khan S, Riazuddin S. Growth factor preconditioning increases the function of diabetes-impaired mesenchymal stem cells. Stem Cells Dev. 2011;20:67–75. doi: 10.1089/scd.2009.0397.
    • (2011) Stem Cells Dev , vol.20 , pp. 67-75
    • Khan, M.1    Akhtar, S.2    Mohsin, S.3    N Khan, S.4    Riazuddin, S.5
  • 44
    • 84878722569 scopus 로고    scopus 로고
    • Cardiopoietic stem cell therapy in heart failure: The C-CURE (Cardiopoietic stem Cell therapy in heart failURE) multicenter randomized trial with lineage-specified biologics
    • Bartunek J, Behfar A, Dolatabadi D, et al. Cardiopoietic stem cell therapy in heart failure: the C-CURE (Cardiopoietic stem Cell therapy in heart failURE) multicenter randomized trial with lineage-specified biologics. J Am Coll Cardiol. 2013;61:2329–2338. doi: 10.1016/j.jacc.2013.02.071.
    • (2013) J Am Coll Cardiol , vol.61 , pp. 2329-2338
    • Bartunek, J.1    Behfar, A.2    Dolatabadi, D.3
  • 46
    • 85016214953 scopus 로고    scopus 로고
    • Cardiopoietic cell therapy for advanced ischaemic heart failure: Results at 39 weeks of the prospective, randomized, double blind, sham-controlled CHART-1 clinical trial
    • CHART Program
    • Bartunek J, Terzic A, Davison BA, et al; CHART Program. Cardiopoietic cell therapy for advanced ischaemic heart failure: results at 39 weeks of the prospective, randomized, double blind, sham-controlled CHART-1 clinical trial. Eur Heart J. 2017;38:648–660. doi: 10.1093/eurheartj/ehw543.
    • (2017) Eur Heart J , vol.38 , pp. 648-660
    • Bartunek, J.1    Terzic, A.2    Davison, B.A.3
  • 47
    • 84899650478 scopus 로고    scopus 로고
    • The inflammatory response in myocardial injury, repair, and remodelling
    • Frangogiannis NG. The inflammatory response in myocardial injury, repair, and remodelling. Nat Rev Cardiol. 2014;11:255–265. doi: 10.1038/nrcardio.2014.28.
    • (2014) Nat Rev Cardiol , vol.11 , pp. 255-265
    • Frangogiannis, N.G.1
  • 48
    • 84878639477 scopus 로고    scopus 로고
    • Acute preconditioning of cardiac progenitor cells with hydrogen peroxide enhances angiogenic pathways following ischemia-reperfusion injury
    • Pendergrass KD, Boopathy AV, Seshadri G, Maiellaro-Rafferty K, Che PL, Brown ME, Davis ME. Acute preconditioning of cardiac progenitor cells with hydrogen peroxide enhances angiogenic pathways following ischemia-reperfusion injury. Stem Cells Dev. 2013;22:2414–2424. doi: 10.1089/scd.2012.0673.
    • (2013) Stem Cells Dev , vol.22 , pp. 2414-2424
    • Pendergrass, K.D.1    Boopathy, A.V.2    Seshadri, G.3    Maiellaro-Rafferty, K.4    Che, P.L.5    Brown, M.E.6    Davis, M.E.7
  • 49
    • 77950564444 scopus 로고    scopus 로고
    • Reactive oxygen species inhibit adhesion of mesenchymal stem cells implanted into ischemic myocardium via interference of focal adhesion complex
    • Song H, Cha MJ, Song BW, Kim IK, Chang W, Lim S, Choi EJ, Ham O, Lee SY, Chung N, Jang Y, Hwang KC. Reactive oxygen species inhibit adhesion of mesenchymal stem cells implanted into ischemic myocardium via interference of focal adhesion complex. Stem Cells. 2010;28:555–563. doi: 10.1002/stem.302.
    • (2010) Stem Cells , vol.28 , pp. 555-563
    • Song, H.1    Cha, M.J.2    Song, B.W.3    Kim, I.K.4    Chang, W.5    Lim, S.6    Choi, E.J.7    Ham, O.8    Lee, S.Y.9    Chung, N.10    Jang, Y.11    Hwang, K.C.12
  • 50
    • 40949085086 scopus 로고    scopus 로고
    • Transplantation of hypoxia-preconditioned mesenchymal stem cells improves infarcted heart function via enhanced survival of implanted cells and angiogenesis
    • Hu X, Yu SP, Fraser JL, Lu Z, Ogle ME, Wang JA, Wei L. Transplantation of hypoxia-preconditioned mesenchymal stem cells improves infarcted heart function via enhanced survival of implanted cells and angiogenesis. J Thorac Cardiovasc Surg. 2008;135:799–808. doi: 10.1016/j.jtcvs.2007.07.071.
    • (2008) J Thorac Cardiovasc Surg , vol.135 , pp. 799-808
    • Hu, X.1    Yu, S.P.2    Fraser, J.L.3    Lu, Z.4    Ogle, M.E.5    Wang, J.A.6    Wei, L.7
  • 51
    • 84864018970 scopus 로고    scopus 로고
    • Hypoxic preconditioning improves survival of cardiac progenitor cells: Role of stromal cell derived factor-1α-CXCR4 axis
    • Yan F, Yao Y, Chen L, Li Y, Sheng Z, Ma G. Hypoxic preconditioning improves survival of cardiac progenitor cells: role of stromal cell derived factor-1α-CXCR4 axis. PLoS One. 2012;7:e37948. doi: 10.1371/journal.pone.0037948.
    • (2012) PLoS One , vol.7 , pp. e37948
    • Yan, F.1    Yao, Y.2    Chen, L.3    Li, Y.4    Sheng, Z.5    Ma, G.6
  • 53
    • 60649103432 scopus 로고    scopus 로고
    • Clinical application of lentiviral vectors - Concepts and practice
    • Schambach A, Baum C. Clinical application of lentiviral vectors - concepts and practice. Curr Gene Ther. 2008;8:474–482.
    • (2008) Curr Gene Ther , vol.8 , pp. 474-482
    • Schambach, A.1    Baum, C.2
  • 54
    • 0036463875 scopus 로고    scopus 로고
    • Lentiviral vectors for gene therapy of HIV-1 infection
    • Mautino MR. Lentiviral vectors for gene therapy of HIV-1 infection. Curr Gene Ther. 2002;2:23–43.
    • (2002) Curr Gene Ther , vol.2 , pp. 23-43
    • Mautino, M.R.1
  • 56
    • 0036242306 scopus 로고    scopus 로고
    • Development of gene therapy for hematopoietic stem cells using lentiviral vectors
    • Woods NB, Ooka A, Karlsson S. Development of gene therapy for hematopoietic stem cells using lentiviral vectors. Leukemia. 2002;16:563–569. doi: 10.1038/sj.leu.2402447.
    • (2002) Leukemia , vol.16 , pp. 563-569
    • Woods, N.B.1    Ooka, A.2    Karlsson, S.3
  • 60
    • 0141796313 scopus 로고    scopus 로고
    • Mesenchymal stem cells modified with Akt prevent remodeling and restore performance of infarcted hearts
    • Mangi AA, Noiseux N, Kong D, He H, Rezvani M, Ingwall JS, Dzau VJ. Mesenchymal stem cells modified with Akt prevent remodeling and restore performance of infarcted hearts. Nat Med. 2003;9:1195–1201. doi: 10.1038/nm912.
    • (2003) Nat Med , vol.9 , pp. 1195-1201
    • Mangi, A.A.1    Noiseux, N.2    Kong, D.3    He, H.4    Rezvani, M.5    Ingwall, J.S.6    Dzau, V.J.7
  • 61
    • 79954836097 scopus 로고    scopus 로고
    • Cardiac progenitor cell commitment is inhibited by nuclear Akt expression
    • Fischer KM, Din S, Gude N, Konstandin MH, Wu W, Quijada P, Sussman MA. Cardiac progenitor cell commitment is inhibited by nuclear Akt expression. Circ Res. 2011;108:960–970. doi: 10.1161/CIRCRESAHA. 110.237156.
    • (2011) Circ Res , vol.108 , pp. 960-970
    • Fischer, K.M.1    Din, S.2    Gude, N.3    Konstandin, M.H.4    Wu, W.5    Quijada, P.6    Sussman, M.A.7
  • 62
    • 35248875838 scopus 로고    scopus 로고
    • SDF-1 expression by mesenchymal stem cells results in trophic support of cardiac myocytes after myocardial infarction
    • Zhang M, Mal N, Kiedrowski M, Chacko M, Askari AT, Popovic ZB, Koc ON, Penn MS. SDF-1 expression by mesenchymal stem cells results in trophic support of cardiac myocytes after myocardial infarction. FASEB J. 2007;21:3197–3207. doi: 10.1096/fj.06-6558com.
    • (2007) FASEB J , vol.21 , pp. 3197-3207
    • Zhang, M.1    Mal, N.2    Kiedrowski, M.3    Chacko, M.4    Askari, A.T.5    Popovic, Z.B.6    Koc, O.N.7    Penn, M.S.8
  • 63
    • 39849097361 scopus 로고    scopus 로고
    • Targeted migration of mesenchymal stem cells modified with CXCR4 gene to infarcted myocardium improves cardiac performance
    • Cheng Z, Ou L, Zhou X, Li F, Jia X, Zhang Y, Liu X, Li Y, Ward CA, Melo LG, Kong D. Targeted migration of mesenchymal stem cells modified with CXCR4 gene to infarcted myocardium improves cardiac performance. Mol Ther. 2008;16:571–579. doi: 10.1038/sj.mt.6300374.
    • (2008) Mol Ther , vol.16 , pp. 571-579
    • Cheng, Z.1    Ou, L.2    Zhou, X.3    Li, F.4    Jia, X.5    Zhang, Y.6    Liu, X.7    Li, Y.8    Ward, C.A.9    Melo, L.G.10    Kong, D.11
  • 64
    • 84887632221 scopus 로고    scopus 로고
    • Cell and gene therapy for severe heart failure patients: The time and place for Pim-1 kinase
    • Siddiqi S, Sussman MA. Cell and gene therapy for severe heart failure patients: the time and place for Pim-1 kinase. Expert Rev Cardiovasc Ther. 2013;11:949–957. doi: 10.1586/14779072.2013.814830.
    • (2013) Expert Rev Cardiovasc Ther , vol.11 , pp. 949-957
    • Siddiqi, S.1    Sussman, M.A.2
  • 65
    • 36849037512 scopus 로고    scopus 로고
    • Pim-1 regulates cardiomyocyte survival downstream of Akt
    • Muraski JA, Rota M, Misao Y, et al. Pim-1 regulates cardiomyocyte survival downstream of Akt. Nat Med. 2007;13:1467–1475. doi: 10.1038/nm1671.
    • (2007) Nat Med , vol.13 , pp. 1467-1475
    • Muraski, J.A.1    Rota, M.2    Misao, Y.3
  • 66
    • 0023637054 scopus 로고
    • Comparison of the human and mouse PIM-1 cDNAs: Nucleotide sequence and immunological identification of the in vitro synthesized PIM-1 protein
    • Domen J, Von Lindern M, Hermans A, Breuer M, Grosveld G, Berns A. Comparison of the human and mouse PIM-1 cDNAs: nucleotide sequence and immunological identification of the in vitro synthesized PIM-1 protein. Oncogene Res. 1987;1:103–112.
    • (1987) Oncogene Res , vol.1 , pp. 103-112
    • Domen, J.1    Von Lindern, M.2    Hermans, A.3    Breuer, M.4    Grosveld, G.5    Berns, A.6
  • 67
    • 0024595556 scopus 로고
    • Predisposition to lymphomagenesis in pim-1 transgenic mice: Cooperation with c-myc and N-myc in murine leukemia virus-induced tumors
    • van Lohuizen M, Verbeek S, Krimpenfort P, Domen J, Saris C, Radaszkiewicz T, Berns A. Predisposition to lymphomagenesis in pim-1 transgenic mice: cooperation with c-myc and N-myc in murine leukemia virus-induced tumors. Cell. 1989;56:673–682.
    • (1989) Cell , vol.56 , pp. 673-682
    • Van Lohuizen, M.1    Verbeek, S.2    Krimpenfort, P.3    Domen, J.4    Saris, C.5    Radaszkiewicz, T.6    Berns, A.7
  • 68
    • 0027497115 scopus 로고
    • Expression of a Pim-1 transgene accelerates lymphoproliferation and inhibits apoptosis in lpr/ lpr mice
    • Möröy T, Grzeschiczek A, Petzold S, Hartmann KU. Expression of a Pim-1 transgene accelerates lymphoproliferation and inhibits apoptosis in lpr/ lpr mice. Proc Natl Acad Sci USA. 1993;90:10734–10738.
    • (1993) Proc Natl Acad Sci USA , vol.90 , pp. 10734-10738
    • Möröy, T.1    Grzeschiczek, A.2    Petzold, S.3    Hartmann, K.U.4
  • 73
    • 49649127162 scopus 로고    scopus 로고
    • Pim kinase-dependent inhibition of c-Myc degradation
    • Zhang Y, Wang Z, Li X, Magnuson NS. Pim kinase-dependent inhibition of c-Myc degradation. Oncogene. 2008;27:4809–4819. doi: 10.1038/onc.2008.123.
    • (2008) Oncogene , vol.27 , pp. 4809-4819
    • Zhang, Y.1    Wang, Z.2    Li, X.3    Magnuson, N.S.4
  • 75
    • 0024297307 scopus 로고
    • Regulation of pim and myb mRNA accumulation by interleukin 2 and interleukin 3 in murine hematopoietic cell lines
    • Dautry F, Weil D, Yu J, Dautry-Varsat A. Regulation of pim and myb mRNA accumulation by interleukin 2 and interleukin 3 in murine hematopoietic cell lines. J Biol Chem. 1988;263:17615–17620.
    • (1988) J Biol Chem , vol.263 , pp. 17615-17620
    • Dautry, F.1    Weil, D.2    Yu, J.3    Dautry-Varsat, A.4
  • 76
    • 71349086917 scopus 로고    scopus 로고
    • PIM1 phosphorylates and negatively regulates ASK1-mediated apoptosis
    • Gu JJ, Wang Z, Reeves R, Magnuson NS. PIM1 phosphorylates and negatively regulates ASK1-mediated apoptosis. Oncogene. 2009;28:4261–4271. doi: 10.1038/onc.2009.276.
    • (2009) Oncogene , vol.28 , pp. 4261-4271
    • Gu, J.J.1    Wang, Z.2    Reeves, R.3    Magnuson, N.S.4
  • 77
    • 58149151542 scopus 로고    scopus 로고
    • IL-3 induces a Pim1-dependent antiapoptotic pathway in primary human basophils
    • Didichenko SA, Spiegl N, Brunner T, Dahinden CA. IL-3 induces a Pim1-dependent antiapoptotic pathway in primary human basophils. Blood. 2008;112:3949–3958. doi: 10.1182/blood-2008-04-149419.
    • (2008) Blood , vol.112 , pp. 3949-3958
    • Didichenko, S.A.1    Spiegl, N.2    Brunner, T.3    Dahinden, C.A.4
  • 78
    • 19344374597 scopus 로고    scopus 로고
    • Pim and Akt oncogenes are independent regulators of hematopoietic cell growth and survival
    • Hammerman PS, Fox CJ, Birnbaum MJ, Thompson CB. Pim and Akt oncogenes are independent regulators of hematopoietic cell growth and survival. Blood. 2005;105:4477–4483. doi: 10.1182/blood-2004-09-3706.
    • (2005) Blood , vol.105 , pp. 4477-4483
    • Hammerman, P.S.1    Fox, C.J.2    Birnbaum, M.J.3    Thompson, C.B.4
  • 79
    • 2942525073 scopus 로고    scopus 로고
    • Identification of Flk-1 target genes in vasculogenesis: Pim-1 is required for endothelial and mural cell differentiation in vitro
    • Zippo A, De Robertis A, Bardelli M, Galvagni F, Oliviero S. Identification of Flk-1 target genes in vasculogenesis: Pim-1 is required for endothelial and mural cell differentiation in vitro. Blood. 2004;103:4536–4544. doi: 10.1182/blood-2003-11-3827.
    • (2004) Blood , vol.103 , pp. 4536-4544
    • Zippo, A.1    De Robertis, A.2    Bardelli, M.3    Galvagni, F.4    Oliviero, S.5
  • 81
    • 13444251304 scopus 로고    scopus 로고
    • The serine/threonine kinase Pim-1
    • Bachmann M, Möröy T. The serine/threonine kinase Pim-1. Int J Biochem Cell Biol. 2005;37:726–730. doi: 10.1016/j.biocel.2004.11.005.
    • (2005) Int J Biochem Cell Biol , vol.37 , pp. 726-730
    • Bachmann, M.1    Möröy, T.2
  • 83
    • 84866735552 scopus 로고    scopus 로고
    • Human cardiac progenitor cells engineered with Pim-I kinase enhance myocardial repair
    • Mohsin S, Khan M, Toko H, et al. Human cardiac progenitor cells engineered with Pim-I kinase enhance myocardial repair. J Am Coll Cardiol. 2012;60:1278–1287. doi: 10.1016/j.jacc.2012.04.047.
    • (2012) J Am Coll Cardiol , vol.60 , pp. 1278-1287
    • Mohsin, S.1    Khan, M.2    Toko, H.3
  • 85
    • 84999635843 scopus 로고    scopus 로고
    • Pim1 kinase overexpression enhances ckit+ cardiac stem cell cardiac repair following myocardial infarction in swine
    • Kulandavelu S, Karantalis V, Fritsch J, et al. Pim1 kinase overexpression enhances ckit+ cardiac stem cell cardiac repair following myocardial infarction in swine. J Am Coll Cardiol. 2016;68:2454–2464. doi: 10.1016/j.jacc.2016.09.925.
    • (2016) J Am Coll Cardiol , vol.68 , pp. 2454-2464
    • Kulandavelu, S.1    Karantalis, V.2    Fritsch, J.3
  • 86
    • 0009583109 scopus 로고
    • Milton Keynes, United Kingdom: Design Studies
    • Cross N. Designerly Ways of Knowing. Milton Keynes, United Kingdom: Design Studies; 1982;3(4):221–227.
    • (1982) Designerly Ways of Knowing , vol.3 , Issue.4 , pp. 221-227
    • Cross, N.1
  • 87
    • 84925286847 scopus 로고    scopus 로고
    • Muscle wasting in disease: Molecular mechanisms and promising therapies
    • Cohen S, Nathan JA, Goldberg AL. Muscle wasting in disease: molecular mechanisms and promising therapies. Nat Rev Drug Discov. 2015;14:58–74. doi: 10.1038/nrd4467.
    • (2015) Nat Rev Drug Discov , vol.14 , pp. 58-74
    • Cohen, S.1    Nathan, J.A.2    Goldberg, A.L.3
  • 88
    • 84948968883 scopus 로고    scopus 로고
    • Human telomere biology: A contributory and interactive factor in aging, disease risks, and protection
    • Blackburn EH, Epel ES, Lin J. Human telomere biology: a contributory and interactive factor in aging, disease risks, and protection. Science. 2015;350:1193–1198. doi: 10.1126/science.aab3389.
    • (2015) Science , vol.350 , pp. 1193-1198
    • Blackburn, E.H.1    Epel, E.S.2    Lin, J.3
  • 89
    • 84923061601 scopus 로고    scopus 로고
    • Role of innate and adaptive immune mechanisms in cardiac injury and repair
    • Epelman S, Liu PP, Mann DL. Role of innate and adaptive immune mechanisms in cardiac injury and repair. Nat Rev Immunol. 2015;15:117–129. doi: 10.1038/nri3800.
    • (2015) Nat Rev Immunol , vol.15 , pp. 117-129
    • Epelman, S.1    Liu, P.P.2    Mann, D.L.3
  • 90
    • 84969443678 scopus 로고    scopus 로고
    • Concise review: Review and perspective of cell dosage and routes of administration from preclinical and clinical studies of stem cell therapy for heart disease
    • Cardiovascular Cell Therapy Research Network
    • Golpanian S, Schulman IH, Ebert RF, Heldman AW, DiFede DL, Yang PC, Wu JC, Bolli R, Perin EC, Moyé L, Simari RD, Wolf A, Hare JM; Cardiovascular Cell Therapy Research Network. Concise review: review and perspective of cell dosage and routes of administration from preclinical and clinical studies of stem cell therapy for heart disease. Stem Cells Transl Med. 2016;5:186–191. doi: 10.5966/sctm.2015-0101.
    • (2016) Stem Cells Transl Med , vol.5 , pp. 186-191
    • Golpanian, S.1    Schulman, I.H.2    Ebert, R.F.3    Heldman, A.W.4    DiFede, D.L.5    Yang, P.C.6    Wu, J.C.7    Bolli, R.8    Perin, E.C.9    Moyé, L.10    Simari, R.D.11    Wolf, A.12    Hare, J.M.13
  • 91
    • 85032470854 scopus 로고    scopus 로고
    • Global position paper on cardiovascular regenerative medicine
    • Fernández-Avilés F, Sanz-Ruiz R, Climent AM, et al. Global position paper on cardiovascular regenerative medicine. Eur Heart J. 2017;38(33):2532–46.
    • (2017) Eur Heart J , vol.38 , Issue.33 , pp. 2532-2546
    • Fernández-Avilés, F.1    Sanz-Ruiz, R.2    Climent, A.M.3
  • 92
    • 84983755295 scopus 로고    scopus 로고
    • Rebuilding the damaged heart: Mesenchymal stem cells, cell-based therapy, and engineered heart tissue
    • Golpanian S, Wolf A, Hatzistergos KE, Hare JM. Rebuilding the damaged heart: mesenchymal stem cells, cell-based therapy, and engineered heart tissue. Physiol Rev. 2016;96:1127–1168. doi: 10.1152/physrev.00019.2015.
    • (2016) Physiol Rev , vol.96 , pp. 1127-1168
    • Golpanian, S.1    Wolf, A.2    Hatzistergos, K.E.3    Hare, J.M.4
  • 93
    • 84928744694 scopus 로고    scopus 로고
    • Challenges in identifying the best source of stem cells for cardiac regeneration therapy
    • Dixit P, Katare R. Challenges in identifying the best source of stem cells for cardiac regeneration therapy. Stem Cell Res Ther. 2015;6:26. doi: 10.1186/s13287-015-0010-8.
    • (2015) Stem Cell Res Ther , vol.6 , pp. 26
    • Dixit, P.1    Katare, R.2
  • 94
    • 84911163905 scopus 로고    scopus 로고
    • Making it stick: Chasing the optimal stem cells for cardiac regeneration
    • Quijada P, Sussman MA. Making it stick: chasing the optimal stem cells for cardiac regeneration. Expert Rev Cardiovasc Ther. 2014;12:1275–1288. doi: 10.1586/14779072.2014.972941.
    • (2014) Expert Rev Cardiovasc Ther , vol.12 , pp. 1275-1288
    • Quijada, P.1    Sussman, M.A.2
  • 95
    • 85010781780 scopus 로고    scopus 로고
    • Myocardial regeneration for humans-Modifying biology and manipulating evolution
    • Broughton KM, Sussman MA. Myocardial regeneration for humans-Modifying biology and manipulating evolution. Circ J. 2017;81:142–148. doi: 10.1253/circj.CJ-16-1228.
    • (2017) Circ J , vol.81 , pp. 142-148
    • Broughton, K.M.1    Sussman, M.A.2
  • 96
    • 11144342747 scopus 로고    scopus 로고
    • Both cell fusion and transdifferentiation account for the transformation of human peripheral blood CD34-positive cells into cardiomyocytes in vivo
    • Zhang S, Wang D, Estrov Z, Raj S, Willerson JT, Yeh ET. Both cell fusion and transdifferentiation account for the transformation of human peripheral blood CD34-positive cells into cardiomyocytes in vivo. Circulation. 2004;110:3803–3807. doi: 10.1161/01.CIR.0000150796.18473.8E.
    • (2004) Circulation , vol.110 , pp. 3803-3807
    • Zhang, S.1    Wang, D.2    Estrov, Z.3    Raj, S.4    Willerson, J.T.5    Yeh, E.T.6
  • 98
    • 43449099736 scopus 로고    scopus 로고
    • Genomic clues to the evolutionary success of polyploid plants
    • Hegarty MJ, Hiscock SJ. Genomic clues to the evolutionary success of polyploid plants. Curr Biol. 2008;18:R435–R444. doi: 10.1016/j.cub. 2008.03.043.
    • (2008) Curr Biol , vol.18 , pp. R435-R444
    • Hegarty, M.J.1    Hiscock, S.J.2
  • 99
    • 0028184403 scopus 로고
    • Stomatal size in fossil plants: Evidence for polyploidy in majority of angiosperms
    • Masterson J. Stomatal size in fossil plants: evidence for polyploidy in majority of angiosperms. Science. 1994;264:421–424. doi: 10.1126/science.264.5157.421.
    • (1994) Science , vol.264 , pp. 421-424
    • Masterson, J.1
  • 101
    • 0035968908 scopus 로고    scopus 로고
    • Comparative genom-ics provides evidence for an ancient genome duplication event in fish
    • Taylor JS, Van de Peer Y, Braasch I, Meyer A. Comparative genom-ics provides evidence for an ancient genome duplication event in fish. Philos Trans R Soc Lond B Biol Sci. 2001;356:1661–1679. doi: 10.1098/rstb.2001.0975.
    • (2001) Philos Trans R Soc Lond B Biol Sci , vol.356 , pp. 1661-1679
    • Taylor, J.S.1    Van de Peer, Y.2    Braasch, I.3    Meyer, A.4
  • 102
    • 0016759509 scopus 로고
    • Denervation effects on DNA replication and mitosis during the initiation of limb regeneration in adult newts
    • Mescher AL, Tassava RA. Denervation effects on DNA replication and mitosis during the initiation of limb regeneration in adult newts. Dev Biol. 1975;44:187–197.
    • (1975) Dev Biol , vol.44 , pp. 187-197
    • Mescher, A.L.1    Tassava, R.A.2
  • 103
    • 0037073890 scopus 로고    scopus 로고
    • Heart regeneration in zebrafish
    • Poss KD, Wilson LG, Keating MT. Heart regeneration in zebrafish. Science. 2002;298:2188–2190. doi: 10.1126/science.1077857.
    • (2002) Science , vol.298 , pp. 2188-2190
    • Poss, K.D.1    Wilson, L.G.2    Keating, M.T.3
  • 104
    • 84869130037 scopus 로고    scopus 로고
    • Gene duplication as a mechanism of genomic adaptation to a changing environment
    • Kondrashov FA. Gene duplication as a mechanism of genomic adaptation to a changing environment. Proc Biol Sci. 2012;279(1749):5048–5057. doi: 10.1098/rspb.2012.1108.
    • (2012) Proc Biol Sci , vol.279 , Issue.1749 , pp. 5048-5057
    • Kondrashov, F.A.1
  • 107
    • 84930787836 scopus 로고    scopus 로고
    • Meta-analysis of cell therapy trials for patients with heart failure
    • Fisher SA, Doree C, Mathur A, Martin-Rendon E. Meta-analysis of cell therapy trials for patients with heart failure. Circ Res. 2015;116:1361–1377. doi: 10.1161/CIRCRESAHA.116.304386.
    • (2015) Circ Res , vol.116 , pp. 1361-1377
    • Fisher, S.A.1    Doree, C.2    Mathur, A.3    Martin-Rendon, E.4


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