-
1
-
-
10744228523
-
Adult cardiac stem cells are multipotent and support myocardial regeneration
-
DOI 10.1016/S0092-8674(03)00687-1
-
Beltrami AP, Barlucchi L, Torella D, Baker M, Limana F, Chimenti S, Kasahara H, Rota M, Musso E, Urbanek K, Leri A, Kajstura J, Nadal- Ginard B, Anversa P. Adult cardiac stem cells are multipotent and support myocardial regeneration. Cell. 2003;114:763-776. (Pubitemid 37186770)
-
(2003)
Cell
, vol.114
, Issue.6
, pp. 763-776
-
-
Beltrami, A.P.1
Barlucchi, L.2
Torella, D.3
Baker, M.4
Limana, F.5
Chimenti, S.6
Kasahara, H.7
Rota, M.8
Musso, E.9
Urbanek, K.10
Leri, A.11
Kajstura, J.12
Nadal-Ginard, B.13
Anversa, P.14
-
2
-
-
40949131866
-
Activation of cardiac progenitor cells reverses the failing heart senescent phenotype and prolongs lifespan
-
DOI 10.1161/CIRCRESAHA.107.165464
-
Gonzalez A, Rota M, Nurzynska D, Misao Y, Tillmanns J, Ojaimi C, Padin-Iruegas ME, Muller P, Esposito G, Bearzi C, Vitale S, Dawn B, Sanganalmath SK, Baker M, Hintze TH, Bolli R, Urbanek K, Hosoda T, Anversa P, Kajstura J, Leri A. Activation of cardiac progenitor cells reverses the failing heart senescent phenotype and prolongs lifespan. Circ Res. 2008;102:597-606. (Pubitemid 351416761)
-
(2008)
Circulation Research
, vol.102
, Issue.5
, pp. 597-606
-
-
Gonzalez, A.1
Rota, M.2
Nurzynska, D.3
Misao, Y.4
Tillmanns, J.5
Ojaimi, C.6
Padin-Iruegas, M.E.7
Muller, P.8
Esposito, G.9
Bearzi, C.10
Vitale, S.11
Dawn, B.12
Sanganalmath, S.K.13
Baker, M.14
Hintze, T.H.15
Bolli, R.16
Urbanek, K.17
Hosoda, T.18
Anversa, P.19
Kajstura, J.20
Leri, A.21
more..
-
3
-
-
38549100777
-
Myocardial Regeneration and Stem Cell Repair
-
DOI 10.1016/j.cpcardiol.2007.11.002, PII S0146280607001430
-
Leri A, Kajstura J, Anversa P, Frishman WH. Myocardial regeneration and stem cell repair. Curr Probl Cardiol. 2008;33:91-153. (Pubitemid 351163350)
-
(2008)
Current Problems in Cardiology
, vol.33
, Issue.3
, pp. 91-153
-
-
Leri, A.1
Kajstura, J.2
Anversa, P.3
Frishman, W.H.4
-
4
-
-
40349103416
-
Formation of large coronary arteries by cardiac progenitor cells
-
DOI 10.1073/pnas.0706315105
-
Tillmanns J, Rota M, Hosoda T, Misao Y, Esposito G, Gonzalez A, Vitale S, Parolin C, Yasuzawa-Amano S, Muraski J, De Angelis A, Lecapitaine N, Siggins RW, Loredo M, Bearzi C, Bolli R, Urbanek K, Leri A, Kajstura J, Anversa P. Formation of large coronary arteries by cardiac progenitor cells. Proc Natl Acad Sci USA. 2008;105:1668-1673. (Pubitemid 351346572)
-
(2008)
Proceedings of the National Academy of Sciences of the United States of America
, vol.105
, Issue.5
, pp. 1668-1673
-
-
Tillmanns, J.1
Rota, M.2
Hosoda, T.3
Misao, Y.4
Esposito, G.5
Gonzalez, A.6
Vitale, S.7
Parolin, C.8
Yasuzawa-Amano, S.9
Muraski, J.10
De Angelis, A.11
LeCapitaine, N.12
Siggins, R.W.13
Loredo, M.14
Bearzi, C.15
Bolli, R.16
Urbanek, K.17
Leri, A.18
Kajstura, J.19
Anversa, P.20
more..
-
5
-
-
20844447692
-
Myocardial regeneration by activation of multipotent cardiac stem cells in ischemic heart failure
-
DOI 10.1073/pnas.0500169102
-
Urbanek K, Torella D, Sheikh F, De Angelis A, Nurzynska D, Silvestri F, Beltrami CA, Bussani R, Beltrami AP, Quaini F, Bolli R, Leri A, Kajstura J, Anversa P. Myocardial regeneration by activation of multipotent cardiac stem cells in ischemic heart failure. Proc Natl Acad Sci USA. 2005;102:8692-8697. (Pubitemid 40862797)
-
(2005)
Proceedings of the National Academy of Sciences of the United States of America
, vol.102
, Issue.24
, pp. 8692-8697
-
-
Urbanek, K.1
Torella, D.2
Sheikh, F.3
De Angelis, A.4
Nurzynska, D.5
Silvestri, F.6
Beltrami, C.A.7
Bussani, R.8
Beltrami, A.P.9
Quaini, F.10
Bolli, R.11
Leri, A.12
Kajstura, J.13
Anversa, P.14
-
6
-
-
73449130151
-
Enhancement of myocardial regeneration through genetic engineering of cardiac progenitor cells expressing Pim-1 kinase
-
Fischer KM, Cottage CT, Wu W, Din S, Gude NA, Avitabile D, Quijada P, Collins BL, Fransioli J, Sussman MA. Enhancement of myocardial regeneration through genetic engineering of cardiac progenitor cells expressing Pim-1 kinase. Circulation. 2009;120:2077-2087.
-
(2009)
Circulation
, vol.120
, pp. 2077-2087
-
-
Fischer, K.M.1
Cottage, C.T.2
Wu, W.3
Din, S.4
Gude, N.A.5
Avitabile, D.6
Quijada, P.7
Collins, B.L.8
Fransioli, J.9
Sussman, M.A.10
-
7
-
-
70350433490
-
Mitochondrial integrity: Preservation through Akt/Pim-1 kinase signaling in the cardiomyocyte
-
Sussman MA. Mitochondrial integrity: preservation through Akt/Pim-1 kinase signaling in the cardiomyocyte. Expert Rev Cardiovasc Ther. 2009;7:929-938.
-
(2009)
Expert Rev Cardiovasc Ther
, vol.7
, pp. 929-938
-
-
Sussman, M.A.1
-
8
-
-
67349210620
-
Cardioprotective stimuli mediate phosphoinositide 3-kinase and phosphoinositide dependent kinase 1 nuclear accumulation in cardiomyocytes
-
Rubio M, Avitabile D, Fischer K, Emmanuel G, Gude N, Miyamoto S, Mishra S, Schaefer EM, Brown JH, Sussman MA. Cardioprotective stimuli mediate phosphoinositide 3-kinase and phosphoinositide dependent kinase 1 nuclear accumulation in cardiomyocytes. J Mol Cell Cardiol. 2009;47:96-103.
-
(2009)
J Mol Cell Cardiol
, vol.47
, pp. 96-103
-
-
Rubio, M.1
Avitabile, D.2
Fischer, K.3
Emmanuel, G.4
Gude, N.5
Miyamoto, S.6
Mishra, S.7
Schaefer, E.M.8
Brown, J.H.9
Sussman, M.A.10
-
9
-
-
68949203099
-
IGF1-induced AKT phosphorylation and cell proliferation are suppressed with the increase in PTEN during luteinization in human granulosa cells
-
Goto M, Iwase A, Harata T, Takigawa S, Suzuki K, Manabe S, Kikkawa F. IGF1-induced AKT phosphorylation and cell proliferation are suppressed with the increase in PTEN during luteinization in human granulosa cells. Reproduction. 2009;137:835-842.
-
(2009)
Reproduction
, vol.137
, pp. 835-842
-
-
Goto, M.1
Iwase, A.2
Harata, T.3
Takigawa, S.4
Suzuki, K.5
Manabe, S.6
Kikkawa, F.7
-
10
-
-
48049086320
-
Myocardial induction of nucleostemin in response to postnatal growth and pathological challenge
-
Siddiqi S, Gude N, Hosoda T, Muraski J, Rubio M, Emmanuel G, Fransioli J, Vitale S, Parolin C, D'Amario D, Schaefer E, Kajstura J, Leri A, Anversa P, Sussman MA. Myocardial induction of nucleostemin in response to postnatal growth and pathological challenge. Circ Res. 2008; 103:89-97.
-
(2008)
Circ Res
, vol.103
, pp. 89-97
-
-
Siddiqi, S.1
Gude, N.2
Hosoda, T.3
Muraski, J.4
Rubio, M.5
Emmanuel, G.6
Fransioli, J.7
Vitale, S.8
Parolin, C.9
D'Amario, D.10
Schaefer, E.11
Kajstura, J.12
Leri, A.13
Anversa, P.14
Sussman, M.A.15
-
11
-
-
34948866710
-
"AKT"ing Lessons for Stem Cells: Regulation of Cardiac Myocyte and Progenitor Cell Proliferation
-
DOI 10.1016/j.tcm.2007.08.003, PII S1050173807001752
-
Sussman M. "AKT"ing lessons for stem cells: regulation of cardiac myocyte and progenitor cell proliferation. Trends Cardiovasc Med. 2007; 17:235-240. (Pubitemid 47532728)
-
(2007)
Trends in Cardiovascular Medicine
, vol.17
, Issue.7
, pp. 235-240
-
-
Sussman, M.1
-
12
-
-
34547793039
-
PI3K/Akt and CREB regulate adult neural hippocampal progenitor proliferation and differentiation
-
DOI 10.1002/dneu.20506
-
Peltier J, O'Neill A, Schaffer DV. PI3K/Akt and CREB regulate adult neural hippocampal progenitor proliferation and differentiation. Dev Neurobiol. 2007;67:1348-1361. (Pubitemid 47242761)
-
(2007)
Developmental Neurobiology
, vol.67
, Issue.10
, pp. 1348-1361
-
-
Peltier, J.1
O'Neill, A.2
Schaffer, D.V.3
-
13
-
-
33846785187
-
Deactivation of Akt and STAT3 signaling promotes apoptosis, inhibits proliferation, and enhances the sensitivity of hepatocellular carcinoma cells to an anticancer agent, Atiprimod
-
DOI 10.1158/1535-7163.MCT-06-0561
-
Choudhari SR, Khan MA, Harris G, Picker D, Jacob GS, Block T, Shailubhai K. Deactivation of Akt and STAT3 signaling promotes apoptosis, inhibits proliferation, and enhances the sensitivity of hepatocellular carcinoma cells to an anticancer agent, Atiprimod. Mol Cancer Ther. 2007;6:112-121. (Pubitemid 46206673)
-
(2007)
Molecular Cancer Therapeutics
, vol.6
, Issue.1
, pp. 112-121
-
-
Choudhari, S.R.1
Khan, M.A.2
Harris, G.3
Picker, D.4
Jacob, G.S.5
Block, T.6
Shailubhai, K.7
-
14
-
-
33747384625
-
Akt promotes increased cardiomyocyte cycling and expansion of the cardiac progenitor cell population
-
DOI 10.1161/01.RES.0000236754.21499.1c, PII 0000301220060818000011
-
Gude N, Muraski J, Rubio M, Kajstura J, Schaefer E, Anversa P, Sussman MA. Akt promotes increased cardiomyocyte cycling and expansion of the cardiac progenitor cell population. Circ Res. 2006;99:381-388. (Pubitemid 44253694)
-
(2006)
Circulation Research
, vol.99
, Issue.4
, pp. 381-388
-
-
Gude, N.1
Muraski, J.2
Rubio, M.3
Kajstura, J.4
Schaefer, E.5
Anversa, P.6
Sussman, M.A.7
-
15
-
-
33747386867
-
Effects of Akt on cardiac myocytes: Location counts
-
DOI 10.1161/01.RES.0000239409.90634.a9, PII 0000301220060818000003
-
Catalucci D, Condorelli G. Effects of Akt on cardiac myocytes: location counts. Circ Res. 2006;99:339-341. (Pubitemid 44253686)
-
(2006)
Circulation Research
, vol.99
, Issue.4
, pp. 339-341
-
-
Catalucci, D.1
Condorelli, G.2
-
16
-
-
3543028648
-
Myc-induced proliferation and transformation require Akt-mediated phosphorylation of FoxO proteins
-
DOI 10.1038/sj.emboj.7600279
-
Bouchard C, Marquardt J, Bras A, Medema RH, Eilers M. Myc-induced proliferation and transformation require Akt-mediated phosphorylation of FoxO proteins. EMBO J. 2004;23:2830-2840. (Pubitemid 39013555)
-
(2004)
EMBO Journal
, vol.23
, Issue.14
, pp. 2830-2840
-
-
Bouchard, C.1
Marquardt, J.2
Bras, A.3
Medema, R.H.4
Eilers, M.5
-
17
-
-
0344011955
-
Akt Controls Vascular Smooth Muscle Cell Proliferation in Vitro and in Vivo by Delaying G1/S Exit
-
DOI 10.1161/01.RES.0000105086.31909.1B
-
Stabile E, Zhou YF, Saji M, Castagna M, Shou M, Kinnaird TD, Baffour R, Ringel MD, Epstein SE, Fuchs S. Akt controls vascular smooth muscle cell proliferation in vitro and in vivo by delaying G1/S exit. Circ Res. 2003;93:1059-1065. (Pubitemid 37485036)
-
(2003)
Circulation Research
, vol.93
, Issue.11
, pp. 1059-1065
-
-
Stabile, E.1
Zhou, Y.F.2
Saji, M.3
Castagna, M.4
Shou, M.5
Kinnaird, T.D.6
Baffour, R.7
Ringel, M.D.8
Epstein, S.E.9
Fuchs, S.10
-
18
-
-
0034941567
-
Cip1 regulates PCNA binding and proliferation of endothelial cells
-
DOI 10.1128/MCB.21.16.5644-5657.2001
-
Rossig L, Jadidi AS, Urbich C, Badorff C, Zeiher AM, Dimmeler S. Akt-dependent phosphorylation of p21(Cip1) regulates PCNA binding and proliferation of endothelial cells. Mol Cell Biol. 2001;21:5644-5657. (Pubitemid 32702467)
-
(2001)
Molecular and Cellular Biology
, vol.21
, Issue.16
, pp. 5644-5657
-
-
Rossig, L.1
Jadidi, A.S.2
Urbich, C.3
Badorff, C.4
Zeiher, A.M.5
Dimmeler, S.6
-
19
-
-
65649128494
-
Early beneficial effects of bone marrow-derived mesenchymal stem cells overexpressing Akt on cardiac metabolism after myocardial infarction
-
Gnecchi M, He H, Melo LG, Noiseaux N, Morello F, de Boer RA, Zhang L, Pratt RE, Dzau VJ, Ingwall JS. Early beneficial effects of bone marrow-derived mesenchymal stem cells overexpressing Akt on cardiac metabolism after myocardial infarction. Stem Cells. 2009;27:971-979.
-
(2009)
Stem Cells
, vol.27
, pp. 971-979
-
-
Gnecchi, M.1
He, H.2
Melo, L.G.3
Noiseaux, N.4
Morello, F.5
De Boer, R.A.6
Zhang, L.7
Pratt, R.E.8
Dzau, V.J.9
Ingwall, J.S.10
-
20
-
-
36849037512
-
Pim-1 regulates cardiomyocyte survival downstream of Akt
-
DOI 10.1038/nm1671, PII NM1671
-
Muraski JA, Rota M, Misao Y, Fransioli J, Cottage C, Gude N, Esposito G, Delucchi F, Arcarese M, Alvarez R, Siddiqi S, Emmanuel GN, Wu W, Fischer K, Martindale JJ, Glembotski CC, Leri A, Kajstura J, Magnuson N, Berns A, Beretta RM, Houser SR, Schaefer EM, Anversa P, Sussman MA. Pim-1 regulates cardiomyocyte survival downstream of Akt. Nat Med. 2007;13:1467-1475. (Pubitemid 350224243)
-
(2007)
Nature Medicine
, vol.13
, Issue.12
, pp. 1467-1475
-
-
Muraski, J.A.1
Rota, M.2
Misao, Y.3
Fransioli, J.4
Cottage, C.5
Gude, N.6
Esposito, G.7
Delucchi, F.8
Arcarese, M.9
Alvarez, R.10
Siddiqi, S.11
Emmanuel, G.N.12
Wu, W.13
Fischer, K.14
Martindale, J.J.15
Glembotski, C.C.16
Leri, A.17
Kajstura, J.18
Magnuson, N.19
Berns, A.20
Beretta, R.M.21
Houser, S.R.22
Schaefer, E.M.23
Anversa, P.24
Sussman, M.A.25
more..
-
21
-
-
33747035594
-
Nuclear targeting of Akt antagonizes aspects of cardiomyocte hypertrophy
-
DOI 10.1073/pnas.0510138103
-
Tsujita Y, Muraski J, Shiraishi I, Kato T, Kajstura J, Anversa P, Sussman MA. Nuclear targeting of Akt antagonizes aspects of cardiomyocyte hypertrophy. Proc Natl Acad Sci USA. 2006;103:11946-11951. (Pubitemid 44215791)
-
(2006)
Proceedings of the National Academy of Sciences of the United States of America
, vol.103
, Issue.32
, pp. 11946-11951
-
-
Tsujita, Y.1
Muraski, J.2
Shiraishi, I.3
Kato, T.4
Kajstura, J.5
Anversa, P.6
Sussman, M.A.7
-
22
-
-
33751038565
-
Mesenchymal stem cells overexpressing Akt dramatically repair infarcted myocardium and improve cardiac function despite infrequent cellular fusion or differentiation
-
DOI 10.1016/j.ymthe.2006.05.016, PII S1525001606002140
-
Noiseux N, Gnecchi M, Lopez-Ilasaca M, Zhang L, Solomon SD, Deb A, Dzau VJ, Pratt RE. Mesenchymal stem cells overexpressing Akt dramatically repair infarcted myocardium and improve cardiac function despite infrequent cellular fusion or differentiation. Mol Ther. 2006;14:840-850. (Pubitemid 44752717)
-
(2006)
Molecular Therapy
, vol.14
, Issue.6
, pp. 840-850
-
-
Noiseux, N.1
Gnecchi, M.2
Lopez-Ilasaca, M.3
Zhang, L.4
Solomon, S.D.5
Deb, A.6
Dzau, V.J.7
Pratt, R.E.8
-
23
-
-
33646252939
-
Evidence supporting paracrine hypothesis for Akt-modified mesenchymal stem cell-mediated cardiac protection and functional improvement
-
DOI 10.1096/fj.05-5211com
-
Gnecchi M, He H, Noiseux N, Liang OD, Zhang L, Morello F, Mu H, Melo LG, Pratt RE, Ingwall JS, Dzau VJ. Evidence supporting paracrine hypothesis for Akt-modified mesenchymal stem cell-mediated cardiac protection and functional improvement. FASEB J. 2006;20:661-669. (Pubitemid 44933310)
-
(2006)
FASEB Journal
, vol.20
, Issue.6
, pp. 661-669
-
-
Gnecchi, M.1
He, H.2
Noiseux, N.3
Liang, O.D.4
Zhang, L.5
Morello, F.6
Mu, H.7
Melo, L.G.8
Pratt, R.E.9
Ingwall, J.S.10
Dzau, V.J.11
-
24
-
-
33644699984
-
Nuclear targeting of Akt enhances ventricular function and myocyte contractility
-
Rota M, Boni A, Urbanek K, Padin-Iruegas ME, Kajstura TJ, Fiore G, Kubo H, Sonnenblick EH, Musso E, Houser SR, Leri A, Sussman MA, Anversa P. Nuclear targeting of Akt enhances ventricular function and myocyte contractility. Circ Res. 2005;97:1332-1341.
-
(2005)
Circ Res
, vol.97
, pp. 1332-1341
-
-
Rota, M.1
Boni, A.2
Urbanek, K.3
Padin-Iruegas, M.E.4
Kajstura, T.J.5
Fiore, G.6
Kubo, H.7
Sonnenblick, E.H.8
Musso, E.9
Houser, S.R.10
Leri, A.11
Sussman, M.A.12
Anversa, P.13
-
25
-
-
1842830427
-
Nuclear Targetin of Akt Enhances Kinase Activity and Survival of Cardiomyocytes
-
DOI 10.1161/01.RES.0000124394.01180.BE
-
Shiraishi I, Melendez J, Ahn Y, Skavdahl M, Murphy E, Welch S, Schaefer E, Walsh K, Rosenzweig A, Torella D, Nurzynska D, Kajstura J, Leri A, Anversa P, Sussman MA. Nuclear targeting of Akt enhances kinase activity and survival of cardiomyocytes. Circ Res. 2004;94: 884-891. (Pubitemid 38490065)
-
(2004)
Circulation Research
, vol.94
, Issue.7
, pp. 884-891
-
-
Shiraishi, I.1
Melendez, J.2
Ahn, Y.3
Skavdahl, M.4
Murphy, E.5
Welch, S.6
Schaefer, E.7
Walsh, K.8
Rosenzweig, A.9
Torella, D.10
Nurzynska, D.11
Kajstura, J.12
Leri, A.13
Anversa, P.14
Sussman, M.A.15
-
26
-
-
0141796313
-
Mesenchymal stem cells modified with Akt prevent remodeling and restore performance of infarcted hearts
-
DOI 10.1038/nm912
-
Mangi AA, Noiseux N, Kong D, He H, Rezvani M, Ingwall JS, Dzau VJ. Mesenchymal stem cells modified with Akt prevent remodeling and restore performance of infarcted hearts. Nat Med. 2003;9:1195-1201. (Pubitemid 37173705)
-
(2003)
Nature Medicine
, vol.9
, Issue.9
, pp. 1195-1201
-
-
Mangi, A.A.1
Noiseux, N.2
Kong, D.3
He, H.4
Rezvani, M.5
Ingwall, J.S.6
Dzau, V.J.7
-
27
-
-
33644754585
-
Akt induces β-cell proliferation by regulating cyclin D1, cyclin D2, and p21 levels and cyclin-dependent kinase-4 activity
-
DOI 10.2337/diabetes.55.02.06.db05-0757
-
Fatrai S, Elghazi L, Balcazar N, Cras-Meneur C, Krits I, Kiyokawa H, Bernal-Mizrachi E. Akt induces beta-cell proliferation by regulating cyclin D1, cyclin D2, and p21 levels and cyclin-dependent kinase-4 activity. Diabetes. 2006;55:318-325. (Pubitemid 43343259)
-
(2006)
Diabetes
, vol.55
, Issue.2
, pp. 318-325
-
-
Fatrai, S.1
Elghazi, L.2
Balcazar, N.3
Cras-Meneur, C.4
Krits, I.5
Kiyokawa, H.6
Bernal-Mizrachi, E.7
-
28
-
-
43449104712
-
Activation of Notch-mediated protective signaling in the myocardium
-
DOI 10.1161/CIRCRESAHA.107.164749, PII 0000301220080509000007
-
Gude NA, Emmanuel G, Wu W, Cottage CT, Fischer K, Quijada P, Muraski JA, Alvarez R, Rubio M, Schaefer E, Sussman MA. Activation of Notch-mediated protective signaling in the myocardium. Circ Res. 2008;102:1025-1035. (Pubitemid 351667856)
-
(2008)
Circulation Research
, vol.102
, Issue.9
, pp. 1025-1035
-
-
Gude, N.A.1
Emmanuel, G.2
Wu, W.3
Cottage, C.T.4
Fischer, K.5
Quijada, P.6
Muraski, J.A.7
Alvarez, R.8
Rubio, M.9
Schaefer, E.10
Sussman, M.A.11
-
29
-
-
27644455693
-
Proliferation of cardiomyocytes derived from human embryonic stem cells is mediated via the IGF/PI 3-kinase/Akt signaling pathway
-
DOI 10.1016/j.yjmcc.2005.09.007, PII S0022282805002877
-
McDevitt TC, Laflamme MA, Murry CE. Proliferation of cardiomyocytes derived from human embryonic stem cells is mediated via the IGF/PI 3-kinase/Akt signaling pathway. J Mol Cell Cardiol. 2005;39:865-873. (Pubitemid 41572319)
-
(2005)
Journal of Molecular and Cellular Cardiology
, vol.39
, Issue.6
, pp. 865-873
-
-
McDevitt, T.C.1
Laflamme, M.A.2
Murry, C.E.3
-
30
-
-
33846845067
-
Secreted frizzled related protein 2 (Sfrp2) is the key Akt-mesenchymal stem cell-released paracrine factor mediating myocardial survival and repair
-
DOI 10.1073/pnas.0610024104
-
Mirotsou M, Zhang Z, Deb A, Zhang L, Gnecchi M, Noiseux N, Mu H, Pachori A, Dzau V. Secreted frizzled related protein 2 (Sfrp2) is the key Akt-mesenchymal stem cell-released paracrine factor mediating myocardial survival and repair. Proc Natl Acad Sci USA. 2007;104: 1643-1648. (Pubitemid 46214644)
-
(2007)
Proceedings of the National Academy of Sciences of the United States of America
, vol.104
, Issue.5
, pp. 1643-1648
-
-
Mirotsou, M.1
Zhang, Z.2
Deb, A.3
Zhang, L.4
Gnecchi, M.5
Noiseux, N.6
Mu, H.7
Pachori, A.8
Dzau, V.9
-
31
-
-
30744432102
-
Akt1 regulates pathological angiogenesis, vascular maturation and permeability in vivo
-
DOI 10.1038/nm1307, PII NM1307
-
Chen J, Somanath PR, Razorenova O, Chen WS, Hay N, Bornstein P, Byzova TV. Akt1 regulates pathological angiogenesis, vascular maturation and permeability in vivo. Nat Med. 2005;11:1188-1196. (Pubitemid 43093666)
-
(2005)
Nature Medicine
, vol.11
, Issue.11
, pp. 1188-1196
-
-
Chen, J.1
Somanath, P.R.2
Razorenova, O.3
Chen, W.S.4
Hay, N.5
Bornstein, P.6
Byzova, T.V.7
-
32
-
-
23644446866
-
Akt1/protein kinase Bα is critical for ischemic and VEGF-mediated angiogenesis
-
DOI 10.1172/JCI24726
-
Ackah E, Yu J, Zoellner S, Iwakiri Y, Skurk C, Shibata R, Ouchi N, Easton RM, Galasso G, Birnbaum MJ, Walsh K, Sessa WC. Akt1/protein kinase Balpha is critical for ischemic and VEGF-mediated angiogenesis. J Clin Invest. 2005;115:2119-2127. (Pubitemid 41134153)
-
(2005)
Journal of Clinical Investigation
, vol.115
, Issue.8
, pp. 2119-2127
-
-
Ackah, E.1
Yu, J.2
Zoellner, S.3
Iwakiri, Y.4
Skurk, C.5
Shibata, R.6
Ouchi, N.7
Easton, R.M.8
Galasso, G.9
Birnbaum, M.J.10
Walsh, K.11
Sessa, W.C.12
-
33
-
-
0037188941
-
Role of Akt signaling in vascular homeostasis and angiogenesis
-
DOI 10.1161/01.RES.0000022200.71892.9F
-
Shiojima I, Walsh K. Role of Akt signaling in vascular homeostasis and angiogenesis. Circ Res. 2002;90:1243-1250. (Pubitemid 34787405)
-
(2002)
Circulation Research
, vol.90
, Issue.12
, pp. 1243-1250
-
-
Shiojima, I.1
Walsh, K.2
-
34
-
-
33845711358
-
Regulation of cardiac growth and coronary angiogenesis by the Akt/PKB signaling pathway
-
DOI 10.1101/gad.1492806
-
Shiojima I, Walsh K. Regulation of cardiac growth and coronary angiogenesis by the Akt/PKB signaling pathway. Genes Dev. 2006;20: 3347-3365. (Pubitemid 44969154)
-
(2006)
Genes and Development
, vol.20
, Issue.24
, pp. 3347-3365
-
-
Shiojima, I.1
Walsh, K.2
-
35
-
-
0035947744
-
Myocardial Akt activation and gender: Increased nuclear activity in females versus males
-
Camper-Kirby D, Welch S, Walker A, Shiraishi I, Setchell KD, Schaefer E, Kajstura J, Anversa P, Sussman MA. Myocardial Akt activation and gender: increased nuclear activity in females versus males. Circ Res. 2001;88:1020-1027. (Pubitemid 34137114)
-
(2001)
Circulation Research
, vol.88
, Issue.10
, pp. 1020-1027
-
-
Camper-Kirby, D.1
Welch, S.2
Walker, A.3
Shiraishi, I.4
Setchell, K.D.R.5
Schaefer, E.6
Kajstura, J.7
Anversa, P.8
Sussman, M.A.9
-
36
-
-
0041327804
-
Effect of stromal-cell-derived factor 1 on stem-cell homing and tissue regeneration in ischaemic cardiomyopathy
-
DOI 10.1016/S0140-6736(03)14232-8
-
Askari AT, Unzek S, Popovic ZB, Goldman CK, Forudi F, Kiedrowski M, Rovner A, Ellis SG, Thomas JD, DiCorleto PE, Topol EJ, Penn MS. Effect of stromal-cell-derived factor 1 on stem-cell homing and tissue regeneration in ischaemic cardiomyopathy. Lancet. 2003;362:697-703. (Pubitemid 37101067)
-
(2003)
Lancet
, vol.362
, Issue.9385
, pp. 697-703
-
-
Askari, A.T.1
Unzek, S.2
Popovic, Z.B.3
Goldman, C.K.4
Forudi, F.5
Kiedrowski, M.6
Rovner, A.7
Ellis, S.G.8
Thomas, J.D.9
DiCorleto, P.E.10
Topol, E.J.11
Penn, M.S.12
-
37
-
-
41249095470
-
SDF-1 recruits cardiac stem cell-like cells that depolarize in vivo
-
DOI 10.3727/096368907783338271
-
Unzek S, Zhang M, Mal N, Mills WR, Laurita KR, Penn MS. SDF-1 recruits cardiac stem cell-like cells that depolarize in vivo. Cell Transplant. 2007;16:879-886. (Pubitemid 351448605)
-
(2007)
Cell Transplantation
, vol.16
, Issue.9
, pp. 879-886
-
-
Unzek, S.1
Zhang, M.2
Mal, N.3
Mills, W.R.4
Laurita, K.R.5
Penn, M.S.6
-
38
-
-
67649592237
-
CAMP response element binding protein is required for mouse neural progenitor cell survival and expansion
-
Dworkin S, Malaterre J, Hollande F, Darcy PK, Ramsay RG, Mantamadiotis T. cAMP response element binding protein is required for mouse neural progenitor cell survival and expansion. Stem Cells. 2009;27: 1347-1357.
-
(2009)
Stem Cells
, vol.27
, pp. 1347-1357
-
-
Dworkin, S.1
Malaterre, J.2
Hollande, F.3
Darcy, P.K.4
Ramsay, R.G.5
Mantamadiotis, T.6
-
39
-
-
0141625687
-
Akt helps stem cells heal the heart
-
DOI 10.1038/nm0903-1109
-
Koc ON, Gerson SL. Akt helps stem cells heal the heart. Nat Med. 2003;9:1109-1110. (Pubitemid 37173685)
-
(2003)
Nature Medicine
, vol.9
, Issue.9
, pp. 1109-1110
-
-
Koc, O.N.1
Gerson, S.L.2
-
40
-
-
33646676295
-
The effects of mesenchymal stem cells transduced with Akt in a porcine myocardial infarction model
-
DOI 10.1016/j.cardiores.2006.02.016, PII S0008636306000782
-
Lim SY, Kim YS, Ahn Y, Jeong MH, Hong MH, Joo SY, Nam KI, Cho JG, Kang PM, Park JC. The effects of mesenchymal stem cells transduced with Akt in a porcine myocardial infarction model. Cardiovasc Res. 2006;70:530-542. (Pubitemid 43732376)
-
(2006)
Cardiovascular Research
, vol.70
, Issue.3
, pp. 530-542
-
-
Lim, S.Y.1
Kim, Y.S.2
Ahn, Y.3
Jeong, M.H.4
Hong, M.H.5
Joo, S.Y.6
Nam, K.I.7
Cho, J.G.8
Kang, P.M.9
Park, J.C.10
-
41
-
-
48649110928
-
PI3K/Akt signaling as a key regulatory pathway for chondrocyte terminal differentiation
-
Kita K, Kimura T, Nakamura N, Yoshikawa H, Nakano T. PI3K/Akt signaling as a key regulatory pathway for chondrocyte terminal differentiation. Genes Cells. 2008;13:839-850.
-
(2008)
Genes Cells
, vol.13
, pp. 839-850
-
-
Kita, K.1
Kimura, T.2
Nakamura, N.3
Yoshikawa, H.4
Nakano, T.5
-
42
-
-
58149345104
-
IGF-1-overexpressing mesenchymal stem cells accelerate bone marrow stem cell mobilization via paracrine activation of SDF-1alpha/CXCR4 signaling to promote myocardial repair
-
Haider H, Jiang S, Idris NM, Ashraf M. IGF-1-overexpressing mesenchymal stem cells accelerate bone marrow stem cell mobilization via paracrine activation of SDF-1alpha/CXCR4 signaling to promote myocardial repair. Circ Res. 2008;103:1300-1308.
-
(2008)
Circ Res
, vol.103
, pp. 1300-1308
-
-
Haider, H.1
Jiang, S.2
Idris, N.M.3
Ashraf, M.4
-
43
-
-
33745356932
-
Bone marrow stem cells prevent left ventricular remodeling of ischemic heart through paracrine signaling
-
DOI 10.1161/01.RES.0000225952.61196.39, PII 0000301220060609000012
-
Uemura R, Xu M, Ahmad N, Ashraf M. Bone marrow stem cells prevent left ventricular remodeling of ischemic heart through paracrine signaling. Circ Res. 2006;98:1414-1421. (Pubitemid 43948066)
-
(2006)
Circulation Research
, vol.98
, Issue.11
, pp. 1414-1421
-
-
Uemura, R.1
Xu, M.2
Ahmad, N.3
Ashraf, M.4
-
44
-
-
20244389882
-
Paracrine action accounts for marked protection of ischemic heart by Akt-modified mesenchymal stem cells [2]
-
DOI 10.1038/nm0405-367
-
Gnecchi M, He H, Liang OD, Melo LG, Morello F, Mu H, Noiseux N, Zhang L, Pratt RE, Ingwall JS, Dzau VJ. Paracrine action accounts for marked protection of ischemic heart by Akt-modified mesenchymal stem cells. Nat Med. 2005;11:367-368. (Pubitemid 40562318)
-
(2005)
Nature Medicine
, vol.11
, Issue.4
, pp. 367-368
-
-
Gnecchi, M.1
He, H.2
Liang, O.D.3
Melo, L.G.4
Morello, F.5
Mu, H.6
Noiseux, N.7
Zhang, L.8
Pratt, R.E.9
Ingwall, J.S.10
Dzau, V.J.11
-
46
-
-
77953662351
-
Targeting CREB for cancer therapy: Friend or foe
-
Xiao X, Li BX, Mitton B, Ikeda A, Sakamoto KM. Targeting CREB for cancer therapy: friend or foe. Curr Cancer Drug Targets. 2010;10: 384-391.
-
(2010)
Curr Cancer Drug Targets
, vol.10
, pp. 384-391
-
-
Xiao, X.1
Li, B.X.2
Mitton, B.3
Ikeda, A.4
Sakamoto, K.M.5
-
47
-
-
48249155484
-
Follistatin-like 1 is an Akt-regulated cardioprotective factor that is secreted by the heart
-
Oshima Y, Ouchi N, Sato K, Izumiya Y, Pimentel DR, Walsh K. Follistatin-like 1 is an Akt-regulated cardioprotective factor that is secreted by the heart. Circulation. 2008;117:3099-3108.
-
(2008)
Circulation
, vol.117
, pp. 3099-3108
-
-
Oshima, Y.1
Ouchi, N.2
Sato, K.3
Izumiya, Y.4
Pimentel, D.R.5
Walsh, K.6
-
48
-
-
52949129827
-
VEGF improves survival of mesenchymal stem cells in infarcted hearts
-
Pons J, Huang Y, Arakawa-Hoyt J, Washko D, Takagawa J, Ye J, Grossman W, Su H. VEGF improves survival of mesenchymal stem cells in infarcted hearts. Biochem Biophys Res Commun. 2008;376: 419-422.
-
(2008)
Biochem Biophys Res Commun
, vol.376
, pp. 419-422
-
-
Pons, J.1
Huang, Y.2
Arakawa-Hoyt, J.3
Washko, D.4
Takagawa, J.5
Ye, J.6
Grossman, W.7
Su, H.8
-
49
-
-
70449518977
-
Vascular endothelial growth factor promotes cardiac stem cell migration via the PI3K/Akt pathway
-
Tang J, Wang J, Kong X, Yang J, Guo L, Zheng F, Zhang L, Huang Y, Wan Y. Vascular endothelial growth factor promotes cardiac stem cell migration via the PI3K/Akt pathway. Exp Cell Res. 2009;315: 3521-3531.
-
(2009)
Exp Cell Res
, vol.315
, pp. 3521-3531
-
-
Tang, J.1
Wang, J.2
Kong, X.3
Yang, J.4
Guo, L.5
Zheng, F.6
Zhang, L.7
Huang, Y.8
Wan, Y.9
-
50
-
-
69849084725
-
Mesenchymal stem cells over-expressing SDF-1 promote angiogenesis and improve heart function in experimental myocardial infarction in rats
-
Tang J, Wang J, Yang J, Kong X, Zheng F, Guo L, Zhang L, Huang Y. Mesenchymal stem cells over-expressing SDF-1 promote angiogenesis and improve heart function in experimental myocardial infarction in rats. Eur J Cardiothorac Surg. 2009;36:644-650.
-
(2009)
Eur J Cardiothorac Surg
, vol.36
, pp. 644-650
-
-
Tang, J.1
Wang, J.2
Yang, J.3
Kong, X.4
Zheng, F.5
Guo, L.6
Zhang, L.7
Huang, Y.8
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