메뉴 건너뛰기




Volumn 12, Issue 10, 2018, Pages 985-996

Microbial modulation of the gut microbiome for treating autoimmune diseases

Author keywords

autoimmune diseases; Gut microbes; gut modulation; next generation probiotics; therapeutic probiotics

Indexed keywords

ANTIBIOTIC AGENT; PROBIOTIC AGENT; ANTIINFECTIVE AGENT;

EID: 85054642382     PISSN: 17474124     EISSN: 17474132     Source Type: Journal    
DOI: 10.1080/17474124.2018.1517044     Document Type: Review
Times cited : (42)

References (129)
  • 1
    • 84922858726 scopus 로고    scopus 로고
    • The infant microbiome development: mom matters
    • Mueller NT, Bakacs E, Combellick J, et al. The infant microbiome development: mom matters. Trends Mol Med. 2015;21:109–117.
    • (2015) Trends Mol Med , vol.21 , pp. 109-117
    • Mueller, N.T.1    Bakacs, E.2    Combellick, J.3
  • 2
    • 84953217700 scopus 로고    scopus 로고
    • The infant microbiome: implications for infant health and neurocognitive development
    • Yang I, Corwin EJ, Brennan PA, et al. The infant microbiome: implications for infant health and neurocognitive development. Nurs Res. 2016;65:76–88.
    • (2016) Nurs Res , vol.65 , pp. 76-88
    • Yang, I.1    Corwin, E.J.2    Brennan, P.A.3
  • 3
    • 85027517201 scopus 로고    scopus 로고
    • Development of the gut microbiota in infancy and its impact on health in later life
    • Tanaka M, Nakayama J., Development of the gut microbiota in infancy and its impact on health in later life. Allergol Int. 2017;66:515–522.
    • (2017) Allergol Int , vol.66 , pp. 515-522
    • Tanaka, M.1    Nakayama, J.2
  • 4
    • 84962530235 scopus 로고    scopus 로고
    • Innate sensing of the gut microbiota: modulation of inflammatory and autoimmune diseases
    • Ignacio A, Morales CI, Câmara NOS, et al. Innate sensing of the gut microbiota: modulation of inflammatory and autoimmune diseases. Front Immunol. 2016;77:54.
    • (2016) Front Immunol , vol.77 , pp. 54
    • Ignacio, A.1    Morales, C.I.2    Câmara, N.O.S.3
  • 5
    • 85021455479 scopus 로고    scopus 로고
    • Intestinal dysbiosis and probiotic applications in autoimmune diseases
    • Oliveira GLV, Leite AZ, Higuchi BS, et al. Intestinal dysbiosis and probiotic applications in autoimmune diseases. Immunology. 2017;152:1–12.
    • (2017) Immunology , vol.152 , pp. 1-12
    • Oliveira, G.L.V.1    Leite, A.Z.2    Higuchi, B.S.3
  • 6
    • 79954423741 scopus 로고    scopus 로고
    • The MHC, disease and selection
    • Trowsdale J. The MHC, disease and selection. Immunol Lett. 2011;137:1–8.
    • (2011) Immunol Lett , vol.137 , pp. 1-8
    • Trowsdale, J.1
  • 7
    • 84941024816 scopus 로고    scopus 로고
    • Human autoimmune diseases: a comprehensive update
    • Wang L, Wang FS, Gershwin ME. Human autoimmune diseases: a comprehensive update. J Intern Me. 2015;278:369–395.
    • (2015) J Intern Me , vol.278 , pp. 369-395
    • Wang, L.1    Wang, F.S.2    Gershwin, M.E.3
  • 8
    • 0142219254 scopus 로고    scopus 로고
    • + -adenosine triphosphatase in human gastric autoimmunity
    • + -adenosine triphosphatase in human gastric autoimmunity. J Exp Med. 2003;198:1147–1156.
    • (2003) J Exp Med , vol.198 , pp. 1147-1156
    • Amedei, A.1    Bergman, M.P.2    Appelmelk, B.J.3
  • 9
    • 84903754213 scopus 로고    scopus 로고
    • Rheumatic fever, autoimmunity, and molecular mimicry: the streptococcal connection
    • Cunningham MW. Rheumatic fever, autoimmunity, and molecular mimicry: the streptococcal connection. Int Rev Immunol. 2014;33:314–329.
    • (2014) Int Rev Immunol , vol.33 , pp. 314-329
    • Cunningham, M.W.1
  • 10
    • 84905011139 scopus 로고    scopus 로고
    • Breach of tolerance: primary biliary cirrhosis
    • Wang L, Wang FS, Chang C, et al. Breach of tolerance: primary biliary cirrhosis. Semin Liver Dis. 2014;34:297–317.
    • (2014) Semin Liver Dis , vol.34 , pp. 297-317
    • Wang, L.1    Wang, F.S.2    Chang, C.3
  • 11
    • 85020054526 scopus 로고    scopus 로고
    • Epstein–Barr virus and multiple sclerosis: updating Pender’s hypothesis
    • Laurence M, Benito-León J. Epstein–Barr virus and multiple sclerosis: updating Pender’s hypothesis. Mult Scler Relat Disord. 2017;16:8–14.
    • (2017) Mult Scler Relat Disord , vol.16 , pp. 8-14
    • Laurence, M.1    Benito-León, J.2
  • 12
    • 84892828465 scopus 로고    scopus 로고
    • Diet rapidly and reproducibly alters the human gut microbiome
    • David LA, Maurice CF, Carmody RN, et al. Diet rapidly and reproducibly alters the human gut microbiome. Nature. 2014;505:559–563.
    • (2014) Nature , vol.505 , pp. 559-563
    • David, L.A.1    Maurice, C.F.2    Carmody, R.N.3
  • 13
    • 8144226856 scopus 로고    scopus 로고
    • The gut microbiota as an environmental factor that regulates fat storage
    • Bäckhed F, Ding H, Wang T, et al. The gut microbiota as an environmental factor that regulates fat storage. Proc Natl Acad Sci U S A. 2004;101:15718–15723.
    • (2004) Proc Natl Acad Sci U S A , vol.101 , pp. 15718-15723
    • Bäckhed, F.1    Ding, H.2    Wang, T.3
  • 14
    • 84977496039 scopus 로고    scopus 로고
    • An expansion of rare lineage intestinal microbes characterizes rheumatoid arthritis
    • Chen J, Wright K, Davis JM, et al. An expansion of rare lineage intestinal microbes characterizes rheumatoid arthritis. Genome Med. 2016;8:43.
    • (2016) Genome Med , vol.8 , pp. 43
    • Chen, J.1    Wright, K.2    Davis, J.M.3
  • 15
    • 85043592218 scopus 로고    scopus 로고
    • Diet, genetics, and the gut microbiome drive dynamic changes in plasma metabolites
    • Fujisaka S, Avila-Pacheco J, Soto M, et al. Diet, genetics, and the gut microbiome drive dynamic changes in plasma metabolites. Cell Rep. 2018;22:3072–3086.
    • (2018) Cell Rep , vol.22 , pp. 3072-3086
    • Fujisaka, S.1    Avila-Pacheco, J.2    Soto, M.3
  • 16
    • 84899538713 scopus 로고    scopus 로고
    • Diet, microbiota and autoimmune diseases
    • Vieira SM, Pagovich OE, Kriegel MA. Diet, microbiota and autoimmune diseases. Lupus. 2014;23:518–526.
    • (2014) Lupus , vol.23 , pp. 518-526
    • Vieira, S.M.1    Pagovich, O.E.2    Kriegel, M.A.3
  • 17
    • 84920263464 scopus 로고    scopus 로고
    • The impact of high-fat diet on metabolism and immune defense in small intestine mucosa
    • Wisniewski JR, Friedrich A, Keller T, et al. The impact of high-fat diet on metabolism and immune defense in small intestine mucosa. J Proteome Res. 2015;14:353–365.
    • (2015) J Proteome Res , vol.14 , pp. 353-365
    • Wisniewski, J.R.1    Friedrich, A.2    Keller, T.3
  • 18
    • 12744273405 scopus 로고    scopus 로고
    • Dietary modulation of the human colonic microbiota: updating the concept of prebiotics
    • Gibson GR, Probert HM, Loo JV, et al. Dietary modulation of the human colonic microbiota: updating the concept of prebiotics. Nutr Res Rev. 2004;17:259–275.
    • (2004) Nutr Res Rev , vol.17 , pp. 259-275
    • Gibson, G.R.1    Probert, H.M.2    Loo, J.V.3
  • 19
    • 0029013322 scopus 로고
    • Dietary modulation of the human colonic microbiota: introducing the concept of prebiotics
    • Gibson G, Roberfroid M. Dietary modulation of the human colonic microbiota: introducing the concept of prebiotics. J Nutr. 1995;125:1401–1412.
    • (1995) J Nutr , vol.125 , pp. 1401-1412
    • Gibson, G.1    Roberfroid, M.2
  • 20
    • 84975068615 scopus 로고    scopus 로고
    • Novel perspectives on therapeutic modulation of the gut microbiota
    • McCarville JL, Caminero A, Verdu EF. Novel perspectives on therapeutic modulation of the gut microbiota. Therap Adv Gastroenterol. 2016;9:580–593.
    • (2016) Therap Adv Gastroenterol , vol.9 , pp. 580-593
    • McCarville, J.L.1    Caminero, A.2    Verdu, E.F.3
  • 21
    • 84977507546 scopus 로고    scopus 로고
    • Microbial metabolism of dietary components to bioactive metabolites: opportunities for new therapeutic interventions
    • Zhang LS, Davies SS. Microbial metabolism of dietary components to bioactive metabolites: opportunities for new therapeutic interventions. Genome Med. 2016;8:46.
    • (2016) Genome Med , vol.8 , pp. 46
    • Zhang, L.S.1    Davies, S.S.2
  • 22
    • 85047834810 scopus 로고    scopus 로고
    • The impact of dietary fiber on gut microbiota in host health and disease
    • Makki K, Deehan EC, Walter J, et al. The impact of dietary fiber on gut microbiota in host health and disease. Cell Host Microbe. 2018;23:705–715.
    • (2018) Cell Host Microbe , vol.23 , pp. 705-715
    • Makki, K.1    Deehan, E.C.2    Walter, J.3
  • 23
    • 85033784875 scopus 로고    scopus 로고
    • Dietary and microbial metabolites in the regulation of host immunity
    • Shibata N, Kunisawa J, Kiyono H. Dietary and microbial metabolites in the regulation of host immunity. Front Microbiol. 2017;8:2171.
    • (2017) Front Microbiol , vol.8 , pp. 2171
    • Shibata, N.1    Kunisawa, J.2    Kiyono, H.3
  • 24
    • 84961217329 scopus 로고    scopus 로고
    • The pharmacology and function of receptors for short-chain fatty acids
    • Bolognini D, Tobin AB, Milligan G, et al. The pharmacology and function of receptors for short-chain fatty acids. Mol Pharmacol. 2016;89:388–398.
    • (2016) Mol Pharmacol , vol.89 , pp. 388-398
    • Bolognini, D.1    Tobin, A.B.2    Milligan, G.3
  • 25
    • 84890564250 scopus 로고    scopus 로고
    • Commensal microbe-derived butyrate induces the differentiation of colonic regulatory T cells
    • Furusawa Y, Obata Y, Fukuda S, et al. Commensal microbe-derived butyrate induces the differentiation of colonic regulatory T cells. Nature. 2013;504:446–450.
    • (2013) Nature , vol.504 , pp. 446-450
    • Furusawa, Y.1    Obata, Y.2    Fukuda, S.3
  • 26
    • 84881068658 scopus 로고    scopus 로고
    • The microbial metabolites, short-chain fatty acids, regulate colonic Treg cell homeostasis
    • Smith PM, Howitt MR, Panikov N, et al. The microbial metabolites, short-chain fatty acids, regulate colonic Treg cell homeostasis. Science. 2013;341:569–573.
    • (2013) Science , vol.341 , pp. 569-573
    • Smith, P.M.1    Howitt, M.R.2    Panikov, N.3
  • 27
    • 84892449521 scopus 로고    scopus 로고
    • Activation of Gpr109a, receptor for niacin and the commensal metabolite butyrate, suppresses colonic inflammation and carcinogenesis
    • Singh N, Gurav A, Sivaprakasam S, et al. Activation of Gpr109a, receptor for niacin and the commensal metabolite butyrate, suppresses colonic inflammation and carcinogenesis. Immunity. 2014;40:128–139.
    • (2014) Immunity , vol.40 , pp. 128-139
    • Singh, N.1    Gurav, A.2    Sivaprakasam, S.3
  • 28
    • 84973666361 scopus 로고    scopus 로고
    • The colonic crypt protects stem cells from microbiota-derived metabolites
    • Kaiko GE, Ryu SH, Koues OI, et al. The colonic crypt protects stem cells from microbiota-derived metabolites. Cell. 2016;165:1708–1720.
    • (2016) Cell , vol.165 , pp. 1708-1720
    • Kaiko, G.E.1    Ryu, S.H.2    Koues, O.I.3
  • 29
    • 84883662960 scopus 로고    scopus 로고
    • Vitamin-mediated regulation of intestinal immunity
    • Kunisawa J, Kiyono H. Vitamin-mediated regulation of intestinal immunity. Front Immunol. 2013;4:189.
    • (2013) Front Immunol , vol.4 , pp. 189
    • Kunisawa, J.1    Kiyono, H.2
  • 30
    • 84942085554 scopus 로고    scopus 로고
    • Vitamin-mediated immune regulation in the development of inflammatory diseases
    • Suzuki H, Kunisawa J. Vitamin-mediated immune regulation in the development of inflammatory diseases. Endocrine Metab Immune Disord Drug Targets. 2015;15:212–215.
    • (2015) Endocrine Metab Immune Disord Drug Targets , vol.15 , pp. 212-215
    • Suzuki, H.1    Kunisawa, J.2
  • 32
    • 84879384339 scopus 로고    scopus 로고
    • Gut microbiota composition modifies fecal metabolic profiles in mice
    • Zhao Y, Wu J, J V L, et al. Gut microbiota composition modifies fecal metabolic profiles in mice. J Proteome Res. 2013;12:2987–2999.
    • (2013) J Proteome Res , vol.12 , pp. 2987-2999
    • Zhao, Y.1    Wu, J.2
  • 33
    • 58449119188 scopus 로고    scopus 로고
    • Establishment of the gut microbiota in Western infants
    • Adlerberth I, Wold AE. Establishment of the gut microbiota in Western infants. Acta Paediatr Int J Paediatr. 2009;98:229–238.
    • (2009) Acta Paediatr Int J Paediatr , vol.98 , pp. 229-238
    • Adlerberth, I.1    Wold, A.E.2
  • 34
    • 85019167519 scopus 로고    scopus 로고
    • Modulation of gut microbiota in pathological states
    • Wang Y, Wang B, Wu J, et al. Modulation of gut microbiota in pathological states. Engineering. 2017;3:83–89.
    • (2017) Engineering , vol.3 , pp. 83-89
    • Wang, Y.1    Wang, B.2    Wu, J.3
  • 35
    • 33847378014 scopus 로고    scopus 로고
    • Rapid and noninvasive metabonomic characterization of inflammatory bowel disease
    • Marchesi JR, Holmes E, Khan F, et al. Rapid and noninvasive metabonomic characterization of inflammatory bowel disease. J Proteome Res. 2007;6:546–551.
    • (2007) J Proteome Res , vol.6 , pp. 546-551
    • Marchesi, J.R.1    Holmes, E.2    Khan, F.3
  • 36
    • 79952756960 scopus 로고    scopus 로고
    • Incomplete recovery and individualized responses of the human distal gut microbiota to repeated antibiotic perturbation
    • Dethlefsen L, Relman DA. Incomplete recovery and individualized responses of the human distal gut microbiota to repeated antibiotic perturbation. Proc Natl Acad Sci U S A. 2011;108:4554–4561.
    • (2011) Proc Natl Acad Sci U S A , vol.108 , pp. 4554-4561
    • Dethlefsen, L.1    Relman, D.A.2
  • 37
    • 84931355745 scopus 로고    scopus 로고
    • Dynamic changes in short- and long-term bacterial composition following fecal microbiota transplantation for recurrent Clostridium difficile infection
    • Weingarden A, González A, Vázquez-Baeza Y, et al. Dynamic changes in short- and long-term bacterial composition following fecal microbiota transplantation for recurrent Clostridium difficile infection. Microbiome. 2015;3:10.
    • (2015) Microbiome , vol.3 , pp. 10
    • Weingarden, A.1    González, A.2    Vázquez-Baeza, Y.3
  • 38
    • 84920931626 scopus 로고    scopus 로고
    • Fecal microbiota transplantation broadening its application beyond intestinal disorders
    • Xu MQ, Cao HL, Wang WQ, et al. Fecal microbiota transplantation broadening its application beyond intestinal disorders. World J Gastroenterol. 2015;21:102–111.
    • (2015) World J Gastroenterol , vol.21 , pp. 102-111
    • Xu, M.Q.1    Cao, H.L.2    Wang, W.Q.3
  • 39
    • 84954543513 scopus 로고    scopus 로고
    • Frozen vs fresh fecal microbiota transplantation and clinical resolution of diarrhea in patients with recurrent Clostridium difficile infection: a randomized clinical trial
    • Lee CH, Steiner T, Petrof EO, et al. Frozen vs fresh fecal microbiota transplantation and clinical resolution of diarrhea in patients with recurrent Clostridium difficile infection: a randomized clinical trial. JAMA. 2016;315(2):142–149.
    • (2016) JAMA , vol.315 , Issue.2 , pp. 142-149
    • Lee, C.H.1    Steiner, T.2    Petrof, E.O.3
  • 40
    • 77950251400 scopus 로고    scopus 로고
    • A human gut microbial gene catalog established by metagenomic sequencing
    • Qin J, Li R, Raes J, et al. A human gut microbial gene catalog established by metagenomic sequencing. Nature. 2010;464:59–65.
    • (2010) Nature , vol.464 , pp. 59-65
    • Qin, J.1    Li, R.2    Raes, J.3
  • 41
    • 84896708902 scopus 로고    scopus 로고
    • Microbiota dynamics in patients treated with fecal microbiota transplantation for recurrent Clostridium difficile infection
    • Song Y, Garg S, Girotra M, et al. Microbiota dynamics in patients treated with fecal microbiota transplantation for recurrent Clostridium difficile infection. PLoS ONE. 2013;8:e81330.
    • (2013) PLoS ONE , vol.8
    • Song, Y.1    Garg, S.2    Girotra, M.3
  • 42
    • 84990041963 scopus 로고    scopus 로고
    • Gut microbiota developments with emphasis on inflammatory bowel disease: report from the gut microbiota for health world summit 2016
    • Eppinga H, Fuhler GM, Peppelenbosch MP, et al. Gut microbiota developments with emphasis on inflammatory bowel disease: report from the gut microbiota for health world summit 2016. Gastroenterology. 2016;151:e1–4.
    • (2016) Gastroenterology , vol.151 , pp. e1-e4
    • Eppinga, H.1    Fuhler, G.M.2    Peppelenbosch, M.P.3
  • 43
    • 84883478660 scopus 로고    scopus 로고
    • Cultured gut microbiota from twins discordant for obesity modulate adiposity and metabolic phenotypes in mice
    • Ridaura VK, Faith JJ, Rey FE, et al. Cultured gut microbiota from twins discordant for obesity modulate adiposity and metabolic phenotypes in mice. Science. 2013;341:1241214.
    • (2013) Science , vol.341 , pp. 1241214
    • Ridaura, V.K.1    Faith, J.J.2    Rey, F.E.3
  • 44
    • 85014315210 scopus 로고    scopus 로고
    • Efficacy of sterile fecal filtrate transfer for treating patients with Clostridium difficile infection
    • Ott SJ, Waetzig GH, Rehman A, et al. Efficacy of sterile fecal filtrate transfer for treating patients with Clostridium difficile infection. Gastroenterology. 2017;152:799–811.
    • (2017) Gastroenterology , vol.152 , pp. 799-811
    • Ott, S.J.1    Waetzig, G.H.2    Rehman, A.3
  • 45
    • 84988448914 scopus 로고    scopus 로고
    • Fecal microbiota transplantation and its usage in neuropsychiatric disorders
    • Evrensel A, Ceylan ME. Fecal microbiota transplantation and its usage in neuropsychiatric disorders. Clin Psychopharmacol Neurosci. 2016;14:231.
    • (2016) Clin Psychopharmacol Neurosci , vol.14 , pp. 231
    • Evrensel, A.1    Ceylan, M.E.2
  • 46
    • 85009999827 scopus 로고    scopus 로고
    • Can probiotics modulate human disease by impacting intestinal barrier function?
    • Bron PA, Kleerebezem M, Brummer RJ, et al. Can probiotics modulate human disease by impacting intestinal barrier function? Br J Nutr. 2017;117:93–107.
    • (2017) Br J Nutr , vol.117 , pp. 93-107
    • Bron, P.A.1    Kleerebezem, M.2    Brummer, R.J.3
  • 47
    • 84883418106 scopus 로고    scopus 로고
    • Beneficial metabolic effects of a probiotic via butyrate-induced GLP-1 hormone secretion
    • Yadav H, Lee J-H, Lloyd J, et al. Beneficial metabolic effects of a probiotic via butyrate-induced GLP-1 hormone secretion. J Biol Chem. 2013;288:25088–25097.
    • (2013) J Biol Chem , vol.288 , pp. 25088-25097
    • Yadav, H.1    Lee, J.-H.2    Lloyd, J.3
  • 48
    • 84953255599 scopus 로고    scopus 로고
    • Probiotc VSL#3 prevents autoimmune diabetes by modulating microbiota and promoting indoleamine 2,3-dioxygenase-enriched tolerogenic intestinal environment
    • Dolpady J, Sorini C, Di Pietro C, et al. Probiotc VSL#3 prevents autoimmune diabetes by modulating microbiota and promoting indoleamine 2,3-dioxygenase-enriched tolerogenic intestinal environment. J Diabetes Res. 2016;2016:7569431.
    • (2016) J Diabetes Res , vol.2016 , pp. 7569431
    • Dolpady, J.1    Sorini, C.2    Di Pietro, C.3
  • 49
    • 40849085594 scopus 로고    scopus 로고
    • Lactobacillus casei suppresses experimental arthritis by down regulating T helper 1 effector functions
    • So JS, Kwon HK, Lee CG, et al. Lactobacillus casei suppresses experimental arthritis by down regulating T helper 1 effector functions. Mol Immunol. 2008;45:2690–2699.
    • (2008) Mol Immunol , vol.45 , pp. 2690-2699
    • So, J.S.1    Kwon, H.K.2    Lee, C.G.3
  • 50
    • 52949121387 scopus 로고    scopus 로고
    • Lactobacillus casei potentiates induction of oral tolerance in experimental arthritis
    • So JS, Lee CG, Kwon HK, et al. Lactobacillus casei potentiates induction of oral tolerance in experimental arthritis. Mol Immunol. 2008;46:172–180.
    • (2008) Mol Immunol , vol.46 , pp. 172-180
    • So, J.S.1    Lee, C.G.2    Kwon, H.K.3
  • 51
    • 41549104613 scopus 로고    scopus 로고
    • Strain-dependent effects of probiotic lactobacilli on EAE autoimmunity
    • Maassen CBM, Claassen E. Strain-dependent effects of probiotic lactobacilli on EAE autoimmunity. Vaccine. 2008;26:2056–2057.
    • (2008) Vaccine , vol.26 , pp. 2056-2057
    • Maassen, C.B.M.1    Claassen, E.2
  • 52
    • 77958119730 scopus 로고    scopus 로고
    • Central nervous system demyelinating disease protection by the human commensal Bacteroides fragilis depends on polysaccharide A expression
    • Ochoa-Reparaz J, Mielcarz DW, Ditrio LE, et al. Central nervous system demyelinating disease protection by the human commensal Bacteroides fragilis depends on polysaccharide A expression. J Immunol. 2010;185:4101–4108.
    • (2010) J Immunol , vol.185 , pp. 4101-4108
    • Ochoa-Reparaz, J.1    Mielcarz, D.W.2    Ditrio, L.E.3
  • 53
    • 81055129714 scopus 로고    scopus 로고
    • The lactic acid bacterium Pediococcus acidilactici suppresses autoimmune encephalomyelitis by inducing IL-10-producing regulatory T cells
    • Takata K, Kinoshita M, Okuno T, et al. The lactic acid bacterium Pediococcus acidilactici suppresses autoimmune encephalomyelitis by inducing IL-10-producing regulatory T cells. PLoS ONE. 2011;6:e27644.
    • (2011) PLoS ONE , vol.6
    • Takata, K.1    Kinoshita, M.2    Okuno, T.3
  • 54
    • 84873714598 scopus 로고    scopus 로고
    • Amelioration of experimental autoimmune encephalomyelitis by probiotic mixture is mediated by a shift in T helper cell immune response
    • Kwon HK, Kim GC, Kim Y, et al. Amelioration of experimental autoimmune encephalomyelitis by probiotic mixture is mediated by a shift in T helper cell immune response. Clin Immunol. 2013;146:217–227.
    • (2013) Clin Immunol , vol.146 , pp. 217-227
    • Kwon, H.K.1    Kim, G.C.2    Kim, Y.3
  • 55
    • 85009765423 scopus 로고    scopus 로고
    • Clinical and metabolic response to probiotic supplementation in patients with multiple sclerosis: a randomized, double-blind, placebo-controlled trial
    • Kouchaki E, Tamtaii OR, Salami M, et al. Clinical and metabolic response to probiotic supplementation in patients with multiple sclerosis: a randomized, double-blind, placebo-controlled trial. Clin Nutr. 2017;36:1245–1249.
    • (2017) Clin Nutr , vol.36 , pp. 1245-1249
    • Kouchaki, E.1    Tamtaii, O.R.2    Salami, M.3
  • 56
    • 79958729747 scopus 로고    scopus 로고
    • A randomized, double-blinded, placebo-controlled pilot study of probiotics in active rheumatoid arthritis
    • Pineda MA, Thompson SF, Summers K, et al. A randomized, double-blinded, placebo-controlled pilot study of probiotics in active rheumatoid arthritis. Med Sci Monit. 2011;17:CR347–54.
    • (2011) Med Sci Monit , vol.17 , pp. CR347-CR354
    • Pineda, M.A.1    Thompson, S.F.2    Summers, K.3
  • 57
    • 84990888674 scopus 로고    scopus 로고
    • The effects of orally administered Bacillus coagulans and inulin on prevention and progression of rheumatoid arthritis in rats
    • Abhari K, Shekarforoush SS, Hosseinzadeh S, et al. The effects of orally administered Bacillus coagulans and inulin on prevention and progression of rheumatoid arthritis in rats. Food Nutr Res. 2016;60:30876.
    • (2016) Food Nutr Res , vol.60 , pp. 30876
    • Abhari, K.1    Shekarforoush, S.S.2    Hosseinzadeh, S.3
  • 58
    • 44649149490 scopus 로고    scopus 로고
    • Human derived probiotic Lactobacillus reuteri demonstrate antimicrobial activities targeting diverse enteric bacterial pathogens
    • Spinler J, Taweechotipatr M, Rognerud C, et al. Human derived probiotic Lactobacillus reuteri demonstrate antimicrobial activities targeting diverse enteric bacterial pathogens. Anaerobe. 2008;14:166–171.
    • (2008) Anaerobe , vol.14 , pp. 166-171
    • Spinler, J.1    Taweechotipatr, M.2    Rognerud, C.3
  • 59
    • 83655201459 scopus 로고    scopus 로고
    • Production of bioactive substances by intestinal bacteria as a basis for explaining probiotic mechanisms: bacteriocins and conjugated linoleic acid
    • O’Shea E, Cotter P, Stanton C, et al. Production of bioactive substances by intestinal bacteria as a basis for explaining probiotic mechanisms: bacteriocins and conjugated linoleic acid. Int J Food Microbiol. 2011;152:189–205.
    • (2011) Int J Food Microbiol , vol.152 , pp. 189-205
    • O’Shea, E.1    Cotter, P.2    Stanton, C.3
  • 60
    • 84871670020 scopus 로고    scopus 로고
    • Effects of probiotics on gut microbiota: mechanisms of intestinal immunomodulation and neuromodulation
    • Hemarajata P, Versalovic J. Effects of probiotics on gut microbiota: mechanisms of intestinal immunomodulation and neuromodulation. Ther Adv Gastroenterol. 2013;6:39–51.
    • (2013) Ther Adv Gastroenterol , vol.6 , pp. 39-51
    • Hemarajata, P.1    Versalovic, J.2
  • 61
    • 84908608590 scopus 로고    scopus 로고
    • The gut microbiota, bacterial metabolites and colorectal cancer
    • Louis P, Hold GL, Flint HJ. The gut microbiota, bacterial metabolites and colorectal cancer. Nat Rev Microbiol. 2014;12:661–672.
    • (2014) Nat Rev Microbiol , vol.12 , pp. 661-672
    • Louis, P.1    Hold, G.L.2    Flint, H.J.3
  • 62
    • 84929502588 scopus 로고    scopus 로고
    • Crosstalk between microbiota-derived short-chain fatty acids and intestinal epithelial HIF augments tissue barrier function
    • Kelly CJ, Zheng L, Campbell EL, et al. Crosstalk between microbiota-derived short-chain fatty acids and intestinal epithelial HIF augments tissue barrier function. Cell Host & Microbe. 2015;17:662–671.
    • (2015) Cell Host & Microbe , vol.17 , pp. 662-671
    • Kelly, C.J.1    Zheng, L.2    Campbell, E.L.3
  • 63
    • 84893900668 scopus 로고    scopus 로고
    • Summer meeting 2013: growth and physiology of Bifidobacteria
    • DeVuyst L, Moens F, Selak M. Summer meeting 2013: growth and physiology of Bifidobacteria. J App Microbiol. 2014;116:477–491.
    • (2014) J App Microbiol , vol.116 , pp. 477-491
    • DeVuyst, L.1    Moens, F.2    Selak, M.3
  • 64
    • 84899969247 scopus 로고    scopus 로고
    • Phylogeny, culturing, and metagenomics of the human gut microbiota
    • Walker AW, Duncan SH, Louis P. Phylogeny, culturing, and metagenomics of the human gut microbiota. Trends Microbiol. 2014;22:267–274.
    • (2014) Trends Microbiol , vol.22 , pp. 267-274
    • Walker, A.W.1    Duncan, S.H.2    Louis, P.3
  • 65
    • 84910614571 scopus 로고    scopus 로고
    • Novel opportunities for next-generation probiotics targeting metabolic syndrome
    • Cani PD, Van Hul M. Novel opportunities for next-generation probiotics targeting metabolic syndrome. Curr Opin Biotechnol. 2015;32:21–27.
    • (2015) Curr Opin Biotechnol , vol.32 , pp. 21-27
    • Cani, P.D.1    Van Hul, M.2
  • 66
    • 84930531205 scopus 로고    scopus 로고
    • Manipulating the gut microbiota to maintain health and treat disease
    • Scott KP, Antoine JM, Midtvedt T. Manipulating the gut microbiota to maintain health and treat disease. Microb Ecol Health Dis. 2015;26:25877.
    • (2015) Microb Ecol Health Dis , vol.26 , pp. 25877
    • Scott, K.P.1    Antoine, J.M.2    Midtvedt, T.3
  • 68
    • 84895068197 scopus 로고    scopus 로고
    • Bifidobacteria: their impact on gut microbiota composition and their applications as probiotics in infants
    • Di Gioia D, Aloisio I, Mazzola G. Bifidobacteria: their impact on gut microbiota composition and their applications as probiotics in infants. Appl Microbiol Biotechnol. 2014;98:563–577.
    • (2014) Appl Microbiol Biotechnol , vol.98 , pp. 563-577
    • Di Gioia, D.1    Aloisio, I.2    Mazzola, G.3
  • 69
    • 84912102518 scopus 로고    scopus 로고
    • Intestinal microbiota in health and disease: role of bifidobacterial in gut homeostasis
    • Tojo R, Suárez A, Clemente MG. Intestinal microbiota in health and disease: role of bifidobacterial in gut homeostasis. World J Gastroenterol. 2014;20:15163–15176.
    • (2014) World J Gastroenterol , vol.20 , pp. 15163-15176
    • Tojo, R.1    Suárez, A.2    Clemente, M.G.3
  • 70
    • 84924546208 scopus 로고    scopus 로고
    • The role of probiotic lactic acid bacteria and bifidobacterial in the prevention and treatment of inflammatory bowel disease and other related diseases: a systematic review of randomized human clinical trials
    • Saez-Lara MJ, Gomez-Llorente C, Plaza-Diaz J. The role of probiotic lactic acid bacteria and bifidobacterial in the prevention and treatment of inflammatory bowel disease and other related diseases: a systematic review of randomized human clinical trials. Biomed Res Int. 2015;2015:505878.
    • (2015) Biomed Res Int , vol.2015 , pp. 505878
    • Saez-Lara, M.J.1    Gomez-Llorente, C.2    Plaza-Diaz, J.3
  • 71
    • 84946044287 scopus 로고    scopus 로고
    • Mutual cross-feeding interactions between Bifidobacterium longum NCC2705 and Eubacterium rectale ATCC33656 explain the bifidogenic and butyrogenic effects of arabinoxylan-oligosaccharides
    • Rivière A, Gagnon M, Weckx S. Mutual cross-feeding interactions between Bifidobacterium longum NCC2705 and Eubacterium rectale ATCC33656 explain the bifidogenic and butyrogenic effects of arabinoxylan-oligosaccharides. Appl Environ Microbiol. 2015;81:7767–7781.
    • (2015) Appl Environ Microbiol , vol.81 , pp. 7767-7781
    • Rivière, A.1    Gagnon, M.2    Weckx, S.3
  • 72
    • 84881550079 scopus 로고    scopus 로고
    • Butyricicoccus pullicaecorum in inflammatory bowel disease
    • Eeckhaut V, Machiels K, Perrier C. Butyricicoccus pullicaecorum in inflammatory bowel disease. Gut. 2013;62:1745–1752.
    • (2013) Gut , vol.62 , pp. 1745-1752
    • Eeckhaut, V.1    Machiels, K.2    Perrier, C.3
  • 73
    • 84891743578 scopus 로고    scopus 로고
    • Progress towards butyrate-producing pharmabiotics: Butyricicoccus pullicaecorum capsule and efficacy in TNBS models in comparison with therapeutics
    • Eeckhaut V, Ducatelle R, Sas B. Progress towards butyrate-producing pharmabiotics: Butyricicoccus pullicaecorum capsule and efficacy in TNBS models in comparison with therapeutics. Gut. 2014;63:367.
    • (2014) Gut , vol.63 , pp. 367
    • Eeckhaut, V.1    Ducatelle, R.2    Sas, B.3
  • 74
    • 84926612462 scopus 로고    scopus 로고
    • Faecalibacterium prausnitzii prevents physiological damages in a chronic low-grade inflammation murine model
    • Martín R, Miquel S, Chain F. Faecalibacterium prausnitzii prevents physiological damages in a chronic low-grade inflammation murine model. BMC Microbiol. 2015;15:67.
    • (2015) BMC Microbiol , vol.15 , pp. 67
    • Martín, R.1    Miquel, S.2    Chain, F.3
  • 75
    • 16544392923 scopus 로고    scopus 로고
    • Lactobacillus rhamnosus induces peripheral hyporesponsiveness in stimulated CD4+ T cells via modulation of dendritic cell function
    • Braat H, Van Den Brande J, Van Tol E, et al. Lactobacillus rhamnosus induces peripheral hyporesponsiveness in stimulated CD4+ T cells via modulation of dendritic cell function. Am J Clin Nutr. 2004;80:1618–1625.
    • (2004) Am J Clin Nutr , vol.80 , pp. 1618-1625
    • Braat, H.1    Van Den Brande, J.2    Van Tol, E.3
  • 76
    • 0037843521 scopus 로고    scopus 로고
    • Immunomodulatory consequences of oral administration of Lactobacillus rhamnosus strain GG in healthy volunteers
    • Schultz M, Linde HJ, Lehn N, et al. Immunomodulatory consequences of oral administration of Lactobacillus rhamnosus strain GG in healthy volunteers. J Dairy Res. 2003;70:165–173.
    • (2003) J Dairy Res , vol.70 , pp. 165-173
    • Schultz, M.1    Linde, H.J.2    Lehn, N.3
  • 77
    • 34247891512 scopus 로고    scopus 로고
    • TSLP: an epithelial cell cytokine that regulates T cell differentiation by conditioning dendritic cell maturation
    • Liu Y-J, Soumelis V, Watanabe N, et al. TSLP: an epithelial cell cytokine that regulates T cell differentiation by conditioning dendritic cell maturation. Annu Rev Immunol. 2007;25:193–219.
    • (2007) Annu Rev Immunol , vol.25 , pp. 193-219
    • Liu, Y.-J.1    Soumelis, V.2    Watanabe, N.3
  • 79
    • 55149113944 scopus 로고    scopus 로고
    • Welcome to the neighborhood: epithelial cell-derived cytokines license innate and adaptive immune responses at mucosal sites
    • Saenz SA, Taylor BC, Artis D. Welcome to the neighborhood: epithelial cell-derived cytokines license innate and adaptive immune responses at mucosal sites. Immunol Rev. 2008;226:172–190.
    • (2008) Immunol Rev , vol.226 , pp. 172-190
    • Saenz, S.A.1    Taylor, B.C.2    Artis, D.3
  • 81
    • 84941647193 scopus 로고    scopus 로고
    • Lactic acid bacteria: reviewing the potential of a promising delivery live vector for biomedical purposes
    • Cano-Garrido O, Seras-Franzoso J, Garcia-Fruitós E. Lactic acid bacteria: reviewing the potential of a promising delivery live vector for biomedical purposes. Microb Cell Fact. 2015;14:137.
    • (2015) Microb Cell Fact , vol.14 , pp. 137
    • Cano-Garrido, O.1    Seras-Franzoso, J.2    Garcia-Fruitós, E.3
  • 82
    • 0034714188 scopus 로고    scopus 로고
    • Treatment of murine colitis by Lactococcus lactis secreting interleukin-10
    • Steidler L, Hans W, Schotte L, et al. Treatment of murine colitis by Lactococcus lactis secreting interleukin-10. Science. 2000;289:1352–1355.
    • (2000) Science , vol.289 , pp. 1352-1355
    • Steidler, L.1    Hans, W.2    Schotte, L.3
  • 83
    • 77953359952 scopus 로고    scopus 로고
    • AG013, a mouth rinse formulation of Lactococcus lactis secreting human trefoil factor 1, provides a safe and efficacious therapeutic tool for treating oral mucositis
    • Caluwaerts S, Vandenbroucke K, Steidler L, et al. AG013, a mouth rinse formulation of Lactococcus lactis secreting human trefoil factor 1, provides a safe and efficacious therapeutic tool for treating oral mucositis. Oral Oncol. 2010;46:564–570.
    • (2010) Oral Oncol , vol.46 , pp. 564-570
    • Caluwaerts, S.1    Vandenbroucke, K.2    Steidler, L.3
  • 84
    • 84906827511 scopus 로고    scopus 로고
    • Recombinant Lactococcus lactis can make the difference in antigen-specific immune tolerance induction, the type 1 diabetes case
    • Robert S, Steidler L. Recombinant Lactococcus lactis can make the difference in antigen-specific immune tolerance induction, the type 1 diabetes case. Microb Cell Fact. 2014;13:S11.
    • (2014) Microb Cell Fact , vol.13 , pp. S11
    • Robert, S.1    Steidler, L.2
  • 85
    • 77950799444 scopus 로고    scopus 로고
    • Xylan-regulated delivery of human keratinocyte growth factor-2 to the inflamed colon by the human anaerobic commensal bacterium Bacteroides ovatus
    • et al
    • Hamady ZZ, Scott N, Farrar MD, et al. Xylan-regulated delivery of human keratinocyte growth factor-2 to the inflamed colon by the human anaerobic commensal bacterium Bacteroides ovatus. Gut. 2010;59:461–469.
    • (2010) Gut , vol.59 , pp. 461-469
    • Hamady, Z.Z.1    Scott, N.2    Farrar, M.D.3
  • 86
    • 80051504591 scopus 로고    scopus 로고
    • Treatment of colitis with a commensal gut bacterium engineered to secrete human TGF-β1 under the control of dietary xylan 1
    • et al
    • Hamady ZZ, Scott N, Farrar MD, et al. Treatment of colitis with a commensal gut bacterium engineered to secrete human TGF-β1 under the control of dietary xylan 1. Inflamm Bowel Dis. 2011;17:1925–1935.
    • (2011) Inflamm Bowel Dis , vol.17 , pp. 1925-1935
    • Hamady, Z.Z.1    Scott, N.2    Farrar, M.D.3
  • 87
    • 17644378995 scopus 로고    scopus 로고
    • Engineering of the gut commensal bacterium Bacteroides ovatus to produce and secrete biologically active murine interleukin-2 in response to xylan
    • et al
    • Farrar MD, Whitehead TR, Lan J, et al. Engineering of the gut commensal bacterium Bacteroides ovatus to produce and secrete biologically active murine interleukin-2 in response to xylan. J Appl Microbiol. 2005;98:1191–1197.
    • (2005) J Appl Microbiol , vol.98 , pp. 1191-1197
    • Farrar, M.D.1    Whitehead, T.R.2    Lan, J.3
  • 88
    • 84926186891 scopus 로고    scopus 로고
    • A transgenic probiotic secreting a parasite immunomodulator for site-directed treatment of gut inflammation
    • Whelan RA, Rausch S, Ebner F, et al. A transgenic probiotic secreting a parasite immunomodulator for site-directed treatment of gut inflammation. Mol Ther. 2014;22:1730–1740.
    • (2014) Mol Ther , vol.22 , pp. 1730-1740
    • Whelan, R.A.1    Rausch, S.2    Ebner, F.3
  • 89
    • 84919786957 scopus 로고    scopus 로고
    • Understanding how commensal obligate anaerobic bacteria regulate immune functions in the large intestine
    • Maier E, Anderson RC, Roy NC. Understanding how commensal obligate anaerobic bacteria regulate immune functions in the large intestine. Nutrients. 2015;7:45–73.
    • (2015) Nutrients , vol.7 , pp. 45-73
    • Maier, E.1    Anderson, R.C.2    Roy, N.C.3
  • 90
    • 83655210633 scopus 로고    scopus 로고
    • Modulation of mucosal immune response, tolerance, and proliferation in mice colonized by the mucin-degrader Akkermansia muciniphila
    • Derrien M, Van Baarlen P, Hooiveld G, et al. Modulation of mucosal immune response, tolerance, and proliferation in mice colonized by the mucin-degrader Akkermansia muciniphila. Front Microbiol. 2011;2:166.
    • (2011) Front Microbiol , vol.2 , pp. 166
    • Derrien, M.1    Van Baarlen, P.2    Hooiveld, G.3
  • 91
    • 85049963474 scopus 로고    scopus 로고
    • Akkermansia muciniphila induces gut microbiota remodelling and controls islet autoimmunity in NOD mice
    • Hänninen A, Toivonen R, Pöysti S, et al. Akkermansia muciniphila induces gut microbiota remodelling and controls islet autoimmunity in NOD mice. Gut. 2017; Doi:10.1136/gutjnl-2017-314508.
    • (2017) Gut
    • Hänninen, A.1    Toivonen, R.2    Pöysti, S.3
  • 92
    • 85033576428 scopus 로고    scopus 로고
    • Gut microbiome influences efficacy of PD-1-based immunotherapy against epithelial tumors
    • Routy B, Le Chatelier E, Derosa L, et al. Gut microbiome influences efficacy of PD-1-based immunotherapy against epithelial tumors. Science. 2018;359:91–97.
    • (2018) Science , vol.359 , pp. 91-97
    • Routy, B.1    Le Chatelier, E.2    Derosa, L.3
  • 93
    • 85032951643 scopus 로고    scopus 로고
    • Gut microbes shape response to cancer immunotherapy
    • Kaiser J. Gut microbes shape response to cancer immunotherapy. Science. 2017;358:573.
    • (2017) Science , vol.358 , pp. 573
    • Kaiser, J.1
  • 94
    • 84878465280 scopus 로고    scopus 로고
    • Cross-talk between Akkermansia muciniphila and intestinal epithelium controls diet-induced obesity
    • Everard A, Belzer C, Geurts L, et al. Cross-talk between Akkermansia muciniphila and intestinal epithelium controls diet-induced obesity. Proc Natl Acad Sci U S A. 2013;110:9066–9071.
    • (2013) Proc Natl Acad Sci U S A , vol.110 , pp. 9066-9071
    • Everard, A.1    Belzer, C.2    Geurts, L.3
  • 95
    • 84997701899 scopus 로고    scopus 로고
    • A purified membrane protein from Akkermansia muciniphila or the pasteurized bacterium improves metabolism in obese and diabetic mice
    • Plovier H, Everard A, Druart C, et al. A purified membrane protein from Akkermansia muciniphila or the pasteurized bacterium improves metabolism in obese and diabetic mice. Nat Med. 2017;23:107–113.
    • (2017) Nat Med , vol.23 , pp. 107-113
    • Plovier, H.1    Everard, A.2    Druart, C.3
  • 96
    • 85030150098 scopus 로고    scopus 로고
    • Emerging trends in “smart probiotics”: functional consideration for the development of novel health and industrial applications
    • Hage ER, Hernandez-Sanabria E, Van de Wiele T. Emerging trends in “smart probiotics”: functional consideration for the development of novel health and industrial applications. Front Microbiol. 2017;8:1889.
    • (2017) Front Microbiol , vol.8 , pp. 1889
    • Hage, E.R.1    Hernandez-Sanabria, E.2    Van de Wiele, T.3
  • 97
    • 65249149643 scopus 로고    scopus 로고
    • Characterizing a model human gut microbiota composed of members of its two dominant bacterial phyla
    • Mahowald MA, Rey FE, Seedorf H, et al. Characterizing a model human gut microbiota composed of members of its two dominant bacterial phyla. Proc. Natl Acad Sci U S A. 2009;106:5859–5864.
    • (2009) Proc. Natl Acad Sci U S A , vol.106 , pp. 5859-5864
    • Mahowald, M.A.1    Rey, F.E.2    Seedorf, H.3
  • 98
    • 0347756655 scopus 로고    scopus 로고
    • Commensal anaerobic gut bacteria attenuate inflammation by regulating nuclear-cytoplasmic shutting of PPAR-γ and ReIA
    • Kelly D, Campbell JI, King TP, et al. Commensal anaerobic gut bacteria attenuate inflammation by regulating nuclear-cytoplasmic shutting of PPAR-γ and ReIA. Nat Immunol. 2004;5:104–112.
    • (2004) Nat Immunol , vol.5 , pp. 104-112
    • Kelly, D.1    Campbell, J.I.2    King, T.P.3
  • 99
    • 84877913270 scopus 로고    scopus 로고
    • Bacteroides thetaiotaomicron and Faecalibacterium prausnitzii influence the production of mucus glycans and the development of goblet cells in the colonic epithelium of a gnotobiotic model rodent
    • Wrzosek L, Miquel S, Noordine ML, et al. Bacteroides thetaiotaomicron and Faecalibacterium prausnitzii influence the production of mucus glycans and the development of goblet cells in the colonic epithelium of a gnotobiotic model rodent. BMC Biol. 2013;11:61.
    • (2013) BMC Biol , vol.11 , pp. 61
    • Wrzosek, L.1    Miquel, S.2    Noordine, M.L.3
  • 100
    • 35448985445 scopus 로고    scopus 로고
    • Bacteroides: the good, the bad, and the nitty-gritty
    • Wexler HM. Bacteroides: the good, the bad, and the nitty-gritty. Clin Microbiol Rev. 2007;20:593–621.
    • (2007) Clin Microbiol Rev , vol.20 , pp. 593-621
    • Wexler, H.M.1
  • 101
    • 79956311926 scopus 로고    scopus 로고
    • The toll-like receptor 2 pathway establishes colonization by a commensal of the human microbiota
    • Round JL, Lee SM, Li J, et al. The toll-like receptor 2 pathway establishes colonization by a commensal of the human microbiota. Science. 2011;332:974–977.
    • (2011) Science , vol.332 , pp. 974-977
    • Round, J.L.1    Lee, S.M.2    Li, J.3
  • 102
    • 84894118144 scopus 로고    scopus 로고
    • Microbiota modulate behavioral and physiological abnormalities associated with neurodevelopmental disorders
    • Hsiao EY, McBride SW, Hsien S, et al. Microbiota modulate behavioral and physiological abnormalities associated with neurodevelopmental disorders. Cell. 2013;155:1451–1463.
    • (2013) Cell , vol.155 , pp. 1451-1463
    • Hsiao, E.Y.1    McBride, S.W.2    Hsien, S.3
  • 103
    • 85046992850 scopus 로고    scopus 로고
    • Bacteroides fragilis protects against antibiotic associated diarrhea in rats by modulating intestinal defenses
    • Zhang W, Zhu B, Xu J, et al. Bacteroides fragilis protects against antibiotic associated diarrhea in rats by modulating intestinal defenses. Front Immunol. 2018;9:1040.
    • (2018) Front Immunol , vol.9 , pp. 1040
    • Zhang, W.1    Zhu, B.2    Xu, J.3
  • 104
    • 44449106055 scopus 로고    scopus 로고
    • A microbial symbiosis factor prevents intestinal inflammatory disease
    • Mazmanian SK, Round JL, Kasper DL. A microbial symbiosis factor prevents intestinal inflammatory disease. Nature. 2008;453:620–625.
    • (2008) Nature , vol.453 , pp. 620-625
    • Mazmanian, S.K.1    Round, J.L.2    Kasper, D.L.3
  • 105
    • 84953252234 scopus 로고    scopus 로고
    • Faecalibacterium prausnitzii A2-165 has a high capacity to induce IL-10 in human and murine dendritic cells and modulates T cell responses
    • Rossi O, Van Berkel LA, Chain F, et al. Faecalibacterium prausnitzii A2-165 has a high capacity to induce IL-10 in human and murine dendritic cells and modulates T cell responses. Sci Rep. 2016;6:18507.
    • (2016) Sci Rep , vol.6 , pp. 18507
    • Rossi, O.1    Van Berkel, L.A.2    Chain, F.3
  • 106
    • 84953856299 scopus 로고    scopus 로고
    • Modulation of the human gut microbiota by dietary fibres occurs at the species level
    • Chung WS, Walker AW, Louis P, et al. Modulation of the human gut microbiota by dietary fibres occurs at the species level. BMC Biol. 2016;1:3.
    • (2016) BMC Biol , vol.1 , pp. 3
    • Chung, W.S.1    Walker, A.W.2    Louis, P.3
  • 107
    • 85021740602 scopus 로고    scopus 로고
    • Functional characterization of novel Faecalibacterium prausnitzii strains isolated from healthy volunteers: a step forward in the use of F. prausnitzii as a next-generation probiotic
    • Martín R, Miquel S, Benevides L, et al. Functional characterization of novel Faecalibacterium prausnitzii strains isolated from healthy volunteers: a step forward in the use of F. prausnitzii as a next-generation probiotic. Front Microbiol. 2017;8:1226.
    • (2017) Front Microbiol , vol.8 , pp. 1226
    • Martín, R.1    Miquel, S.2    Benevides, L.3
  • 108
    • 84884816918 scopus 로고    scopus 로고
    • Faecalibacterium prausnitzii upregulates regulatory T cells and anti-inflammatory cytokines in treating TNBS-induced colitis
    • Qiu X, Zhang M, Yang X, et al. Faecalibacterium prausnitzii upregulates regulatory T cells and anti-inflammatory cytokines in treating TNBS-induced colitis. J Crohn’s Colitis. 2013;11:e558–68.
    • (2013) J Crohn’s Colitis , vol.11 , pp. e558-e568
    • Qiu, X.1    Zhang, M.2    Yang, X.3
  • 109
    • 77957075815 scopus 로고    scopus 로고
    • Impact of diet in shaping gut microbiota revealed by a comparative study in children from Europe and rural Africa
    • Filippo CD, Cavalieri D, Paola MD, et al. Impact of diet in shaping gut microbiota revealed by a comparative study in children from Europe and rural Africa. Proc Natl Acad Sci U S A. 2010;107:14691–14696.
    • (2010) Proc Natl Acad Sci U S A , vol.107 , pp. 14691-14696
    • Filippo, C.D.1    Cavalieri, D.2    Paola, M.D.3
  • 110
    • 85017604806 scopus 로고    scopus 로고
    • Evidence of the immune relevance of Prevotella copri, a gut microbe, in patients with rheumatoid arthritis
    • Pianta A, Arvikar S, Strle K, et al. Evidence of the immune relevance of Prevotella copri, a gut microbe, in patients with rheumatoid arthritis. Arthritis Rheumatol. 2017;69:964–975.
    • (2017) Arthritis Rheumatol , vol.69 , pp. 964-975
    • Pianta, A.1    Arvikar, S.2    Strle, K.3
  • 111
    • 84997815933 scopus 로고    scopus 로고
    • Human gut-derived Prevotella histicola suppresses inflammatory arthritis in humanized mice
    • Marietta EV, Murray JA, Luckey DH, et al. Human gut-derived Prevotella histicola suppresses inflammatory arthritis in humanized mice. Arthritis Rheumatol. 2016;68:2878–2888.
    • (2016) Arthritis Rheumatol , vol.68 , pp. 2878-2888
    • Marietta, E.V.1    Murray, J.A.2    Luckey, D.H.3
  • 112
    • 85026854161 scopus 로고    scopus 로고
    • Human gut-derived commensal bacteria suppress CNS inflammatory and demyelinating disease
    • Mangalam A, Shahi SK, Luckey D, et al. Human gut-derived commensal bacteria suppress CNS inflammatory and demyelinating disease. Cell Rep. 2017;20:1269–1277.
    • (2017) Cell Rep , vol.20 , pp. 1269-1277
    • Mangalam, A.1    Shahi, S.K.2    Luckey, D.3
  • 113
    • 84908322572 scopus 로고    scopus 로고
    • Arthritis susceptibility and the gut microbiome
    • Taneja V. Arthritis susceptibility and the gut microbiome. FEBS Lett. 2014;588:4244–4249.
    • (2014) FEBS Lett , vol.588 , pp. 4244-4249
    • Taneja, V.1
  • 114
    • 84860118160 scopus 로고    scopus 로고
    • Loss of sex and age-driven differences in the gut microbiome characterize arthritis-susceptible *0401 mice but not arthritis-resistant *0402 mice
    • Gomez A, Yoeman C, Luckey D, White BA, Taneja V, et al. Loss of sex and age-driven differences in the gut microbiome characterize arthritis-susceptible *0401 mice but not arthritis-resistant *0402 mice. PLoS ONE. 2012;7:e36095.
    • (2012) PLoS ONE , vol.7
    • Gomez, A.1    Yoeman, C.2    Luckey, D.3    White, B.A.4    Taneja, V.5
  • 115
    • 84857965571 scopus 로고    scopus 로고
    • Microencapsulation of probiotic cells for food applications
    • Heidebach T, Först P, Kulozik U. Microencapsulation of probiotic cells for food applications. Crit Rev Food Sci Nutr. 2012;52:291–311.
    • (2012) Crit Rev Food Sci Nutr , vol.52 , pp. 291-311
    • Heidebach, T.1    Först, P.2    Kulozik, U.3
  • 117
    • 85029688885 scopus 로고    scopus 로고
    • Safety of novel microbes for human consumption: practical examples of assessment in the European Union
    • Brodmann T, Endo A, Gueimonde M, et al. Safety of novel microbes for human consumption: practical examples of assessment in the European Union. Front Microbiol. 2017;8:1725.
    • (2017) Front Microbiol , vol.8 , pp. 1725
    • Brodmann, T.1    Endo, A.2    Gueimonde, M.3
  • 118
    • 84923351295 scopus 로고    scopus 로고
    • Regulatory categories of probiotics across the globe: a review representing existing and recommended categorization
    • Arora M, Baldi A. Regulatory categories of probiotics across the globe: a review representing existing and recommended categorization. Indian J Med Microbiol. 2015;33:2–10.
    • (2015) Indian J Med Microbiol , vol.33 , pp. 2-10
    • Arora, M.1    Baldi, A.2
  • 119
    • 84869421349 scopus 로고    scopus 로고
    • Metchnikoff and the microbiome
    • Podolsky SH. Metchnikoff and the microbiome. Lancet. 2012;380:1810–1811.
    • (2012) Lancet , vol.380 , pp. 1810-1811
    • Podolsky, S.H.1
  • 120
    • 84952630944 scopus 로고    scopus 로고
    • The gut microbiome in autoimmunity: sex matters
    • Gomez A, Luckey D, Taneja V. The gut microbiome in autoimmunity: sex matters. Clin Immunol. 2015;159:154–162.
    • (2015) Clin Immunol , vol.159 , pp. 154-162
    • Gomez, A.1    Luckey, D.2    Taneja, V.3
  • 121
    • 85043285818 scopus 로고    scopus 로고
    • Translocation of a gut pathobiont drives autoimmunity in mice and humans
    • Vieira M, Hiltensperger M, Kumar V, et al. Translocation of a gut pathobiont drives autoimmunity in mice and humans. Science. 2018;359:1156–1161.
    • (2018) Science , vol.359 , pp. 1156-1161
    • Vieira, M.1    Hiltensperger, M.2    Kumar, V.3
  • 122
    • 77249133143 scopus 로고    scopus 로고
    • Orally administered L. lactis secreting an anti-TNF nanobody demonstrate efficacy in chronic colitis
    • Vandenbroucke K, De Haard H, Beirnaert E, et al. Orally administered L. lactis secreting an anti-TNF nanobody demonstrate efficacy in chronic colitis. Mucosal Immunol. 2010;3:49–56.
    • (2010) Mucosal Immunol , vol.3 , pp. 49-56
    • Vandenbroucke, K.1    De Haard, H.2    Beirnaert, E.3
  • 123
    • 4143082646 scopus 로고    scopus 로고
    • Active delivery of trefoil factors by genetically modified Lactococcus lactis prevents and heals acute colitis in mice
    • Vandenbroucke K, Hans W, Van Huysse J, et al. Active delivery of trefoil factors by genetically modified Lactococcus lactis prevents and heals acute colitis in mice. Gastroenterology. 2004;127:502–513.
    • (2004) Gastroenterology , vol.127 , pp. 502-513
    • Vandenbroucke, K.1    Hans, W.2    Van Huysse, J.3
  • 124
    • 34547542844 scopus 로고    scopus 로고
    • Prevention and treatment of colitis with Lactococcus lactis secreting the immunomodulatory Yersinia LcrV protein
    • Foligne B, Dessein R, Marceau M, et al. Prevention and treatment of colitis with Lactococcus lactis secreting the immunomodulatory Yersinia LcrV protein. Gastroenterology. 2007;133:862–874.
    • (2007) Gastroenterology , vol.133 , pp. 862-874
    • Foligne, B.1    Dessein, R.2    Marceau, M.3
  • 125
    • 78149270683 scopus 로고    scopus 로고
    • Intragastric administration of a superoxide dismutase-producing recombinant Lactobacillus casei BL23 strain attenuates DSS colitis in mice
    • Watterlot L, Rochat T, Sokol H, et al. Intragastric administration of a superoxide dismutase-producing recombinant Lactobacillus casei BL23 strain attenuates DSS colitis in mice. Int J Food Microbiol. 2010;144:35–41.
    • (2010) Int J Food Microbiol , vol.144 , pp. 35-41
    • Watterlot, L.1    Rochat, T.2    Sokol, H.3
  • 126
    • 33744933432 scopus 로고    scopus 로고
    • A phase I trial with transgenic bacteria expressing interleukin-10 in Crohn’s disease
    • Braat H, Rottiers P, Hommes DW, et al. A phase I trial with transgenic bacteria expressing interleukin-10 in Crohn’s disease. Clin Gastroenterol Hepatol. 2006;4:754–759.
    • (2006) Clin Gastroenterol Hepatol , vol.4 , pp. 754-759
    • Braat, H.1    Rottiers, P.2    Hommes, D.W.3
  • 127
    • 84890608517 scopus 로고    scopus 로고
    • Oral delivery of IL-27 recombinant bacteria attenuates immune colitis in mice
    • Hanson ML, Hixon JA, Li W, et al. Oral delivery of IL-27 recombinant bacteria attenuates immune colitis in mice. Gastroenterology. 2014;146:210–221:e213.
    • (2014) Gastroenterology , vol.146
    • Hanson, M.L.1    Hixon, J.A.2    Li, W.3
  • 128
    • 84860228482 scopus 로고    scopus 로고
    • Reversal of autoimmune diabetes by restoration of antigen-specific tolerance using genetically modified Lactococcus lactis in mice
    • Takiishi T, Korf H, Van Belle TL, et al. Reversal of autoimmune diabetes by restoration of antigen-specific tolerance using genetically modified Lactococcus lactis in mice. J Clin Invest. 2012;122:1717–1725.
    • (2012) J Clin Invest , vol.122 , pp. 1717-1725
    • Takiishi, T.1    Korf, H.2    Van Belle, T.L.3
  • 129
    • 84929294360 scopus 로고    scopus 로고
    • Oral administration of recombinant Lactococcus lactis expressing HSP65 and tandemly repeated P277 reduces the incidence of type I diabetes in non-obese diabetic mice
    • Ma Y, Liu J, Hou J, et al. Oral administration of recombinant Lactococcus lactis expressing HSP65 and tandemly repeated P277 reduces the incidence of type I diabetes in non-obese diabetic mice. PLoS ONE. 2014;9:e105701vv.
    • (2014) PLoS ONE , vol.9
    • Ma, Y.1    Liu, J.2    Hou, J.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.