메뉴 건너뛰기




Volumn 6, Issue 1, 2013, Pages 39-51

Effects of probiotics on gut microbiota: Mechanisms of intestinal immunomodulation and neuromodulation

Author keywords

Diet; Gut microbiota; Immunomodulation; Lactobacillus; Nervous system; Probiotics

Indexed keywords

4 AMINOBUTYRIC ACID; ANTIBIOTIC AGENT; GLUTAMIC ACID; HISTAMINE; HISTIDINE; HISTIDINE DECARBOXYLASE; INTERLEUKIN 10; INTERLEUKIN 12; PROBIOTIC AGENT; SHORT CHAIN FATTY ACID; TRANSCRIPTION FACTOR AP 1; TRANSFORMING GROWTH FACTOR BETA; TUMOR NECROSIS FACTOR;

EID: 84871670020     PISSN: 1756283X     EISSN: 17562648     Source Type: Journal    
DOI: 10.1177/1756283X12459294     Document Type: Review
Times cited : (731)

References (73)
  • 1
    • 84864037467 scopus 로고    scopus 로고
    • Metabolic reconstruction for metagenomic data and its application to the human microbiome
    • Abubucker S. Segata N. Goll J. Schubert A. Izard J. Cantarel B. et al. (2012) Metabolic reconstruction for metagenomic data and its application to the human microbiome. PLoS Comput Biol 8: e1002358.
    • (2012) PLoS Comput Biol , vol.8 , pp. e1002358
    • Abubucker, S.1    Segata, N.2    Goll, J.3    Schubert, A.4    Izard, J.5    Cantarel, B.6
  • 2
    • 44349132270 scopus 로고    scopus 로고
    • Epithelial-cell recognition of commensal bacteria and maintenance of immune homeostasis in the gut
    • Artis D. (2008) Epithelial-cell recognition of commensal bacteria and maintenance of immune homeostasis in the gut. Nat Rev Immunol 8: 411–420.
    • (2008) Nat Rev Immunol , vol.8 , pp. 411-420
    • Artis, D.1
  • 5
    • 81855167104 scopus 로고    scopus 로고
    • Commensal microbiota and myelin autoantigen cooperate to trigger autoimmune demyelination
    • Berer K. Mues M. Koutrolos M. Rasbi Z. Boziki M. Johner C. et al. (2011) Commensal microbiota and myelin autoantigen cooperate to trigger autoimmune demyelination. Nature 479: 538–541.
    • (2011) Nature , vol.479 , pp. 538-541
    • Berer, K.1    Mues, M.2    Koutrolos, M.3    Rasbi, Z.4    Boziki, M.5    Johner, C.6
  • 6
    • 77949362543 scopus 로고    scopus 로고
    • 99th Dahlem Conference on Infection, Inflammation and Chronic Inflammatory Disorders: Psycho-Neuroimmunology and the Intestinal Microbiota: Clinical observations and basic mechanisms
    • Bienenstock J. Collins S. (2010) 99th Dahlem Conference on Infection, Inflammation and Chronic Inflammatory Disorders: Psycho-Neuroimmunology and the Intestinal Microbiota: Clinical observations and basic mechanisms. Clin Exp Immunol 160: 85–91.
    • (2010) Clin Exp Immunol , vol.160 , pp. 85-91
    • Bienenstock, J.1    Collins, S.2
  • 8
    • 80052965474 scopus 로고    scopus 로고
    • Ingestion of Lactobacillus strain regulates emotional behavior and central GABA receptor expression in a mouse via the vagus nerve
    • Bravo J. Forsythe P. Chew M. Escaravage E. Savignac H. Dinan T. et al. (2011) Ingestion of Lactobacillus strain regulates emotional behavior and central GABA receptor expression in a mouse via the vagus nerve. Proc Natl Acad Sci U S A 108: 16050–16055.
    • (2011) Proc Natl Acad Sci U S A , vol.108 , pp. 16050-16055
    • Bravo, J.1    Forsythe, P.2    Chew, M.3    Escaravage, E.4    Savignac, H.5    Dinan, T.6
  • 9
    • 83855165652 scopus 로고    scopus 로고
    • Emerging molecular insights into the interaction between probiotics and the host intestinal mucosa
    • Bron P. van Baarlen P. Kleerebezem M. (2011) Emerging molecular insights into the interaction between probiotics and the host intestinal mucosa. Nat Rev Microbiol 10: 66–78.
    • (2011) Nat Rev Microbiol , vol.10 , pp. 66-78
    • Bron, P.1    van Baarlen, P.2    Kleerebezem, M.3
  • 10
    • 70449574399 scopus 로고    scopus 로고
    • Interplay between obesity and associated metabolic disorders: new insights into the gut microbiota
    • Cani P. Delzenne N. (2009) Interplay between obesity and associated metabolic disorders: new insights into the gut microbiota. Curr Opin Pharmacol 9: 737–743.
    • (2009) Curr Opin Pharmacol , vol.9 , pp. 737-743
    • Cani, P.1    Delzenne, N.2
  • 11
    • 53949089441 scopus 로고    scopus 로고
    • Systemic multicompartmental effects of the gut microbiome on mouse metabolic phenotypes
    • Claus S. Tsang T. Wang Y. Cloarec O. Skordi E. Martin F. et al. (2008) Systemic multicompartmental effects of the gut microbiome on mouse metabolic phenotypes. Mol Syst Biol 4: 219.
    • (2008) Mol Syst Biol , vol.4 , pp. 219
    • Claus, S.1    Tsang, T.2    Wang, Y.3    Cloarec, O.4    Skordi, E.5    Martin, F.6
  • 12
    • 34848880458 scopus 로고    scopus 로고
    • Role of commercial probiotic strains against human pathogen adhesion to intestinal mucus
    • Collado M. Meriluoto J. Salminen S. (2007) Role of commercial probiotic strains against human pathogen adhesion to intestinal mucus. Lett Appl Microbiol 45: 454–460.
    • (2007) Lett Appl Microbiol , vol.45 , pp. 454-460
    • Collado, M.1    Meriluoto, J.2    Salminen, S.3
  • 13
    • 77649323279 scopus 로고    scopus 로고
    • Lactobacillus casei abundance is associated with profound shifts in the infant gut microbiome
    • Cox M. Huang Y. Fujimura K. Liu J. McKean M. Boushey H. et al. (2010) Lactobacillus casei abundance is associated with profound shifts in the infant gut microbiome. PloS ONE 5: e8745.
    • (2010) PloS ONE , vol.5 , pp. e8745
    • Cox, M.1    Huang, Y.2    Fujimura, K.3    Liu, J.4    McKean, M.5    Boushey, H.6
  • 14
    • 84859024348 scopus 로고    scopus 로고
    • Bacterial diversity stabilizes community productivity
    • Eisenhauer N. Scheu S. Jousset A. (2012) Bacterial diversity stabilizes community productivity. PloS ONE 7: e34517.
    • (2012) PloS ONE , vol.7 , pp. e34517
    • Eisenhauer, N.1    Scheu, S.2    Jousset, A.3
  • 15
    • 84993766894 scopus 로고    scopus 로고
    • Food and Agriculture Organization of the United Nations, World Health Organization, Joint FAO/WHO Expert Consultation on Evaluation of Health and Nutritional Properties of Probiotics in Food Including Powder Milk with Live Lactic Acid Bacteria, and Joint FAO/WHO Working Group on Drafting Guidelines for the Evaluation of Probiotics in Food
    • Probiotics in food: health and nutritional properties and guidelines for evaluation Report of a Joint FAO/WHO Expert Consultation on Evaluation of Health and Nutritional Properties of Probiotics in Food Including Powder Milk with Live Lactic Acid Bacteria, Cordoba, Argentina, 1–4 October 2001 [and] Report of a Joint FAO/WHO Working Group on Drafting Guidelines for the Evaluation of Probiotics in Food, London, O.N., Canada, 30 April –1 May 2002 Rome Food and Agriculture Organization of the United Nations, World Health Organization
    • Food and Agriculture Organization of the United Nations, World Health Organization, Joint FAO/WHO Expert Consultation on Evaluation of Health and Nutritional Properties of Probiotics in Food Including Powder Milk with Live Lactic Acid Bacteria, and Joint FAO/WHO Working Group on Drafting Guidelines for the Evaluation of Probiotics in Food (2006) Probiotics in food: health and nutritional properties and guidelines for evaluation. In Report of a Joint FAO/WHO Expert Consultation on Evaluation of Health and Nutritional Properties of Probiotics in Food Including Powder Milk with Live Lactic Acid Bacteria, Cordoba, Argentina, 1–4 October 2001 [and] Report of a Joint FAO/WHO Working Group on Drafting Guidelines for the Evaluation of Probiotics in Food, London, O.N., Canada, 30 April –1 May 2002. Rome: Food and Agriculture Organization of the United Nations, World Health Organization.
    • (2006)
  • 18
    • 80052155761 scopus 로고    scopus 로고
    • Investigating the biological and clinical significance of human dysbioses
    • Frank D. Zhu W. Sartor R. Li E. (2011) Investigating the biological and clinical significance of human dysbioses. Trends Microbiol 19: 427–434.
    • (2011) Trends Microbiol , vol.19 , pp. 427-434
    • Frank, D.1    Zhu, W.2    Sartor, R.3    Li, E.4
  • 19
    • 33744804299 scopus 로고    scopus 로고
    • Metagenomic analysis of the human distal gut microbiome
    • Gill S. Pop M. Deboy R. Eckburg P. Turnbaugh P. Samuel B. et al. (2006) Metagenomic analysis of the human distal gut microbiome. Science 312: 1355–1359.
    • (2006) Science , vol.312 , pp. 1355-1359
    • Gill, S.1    Pop, M.2    Deboy, R.3    Eckburg, P.4    Turnbaugh, P.5    Samuel, B.6
  • 20
    • 79955025122 scopus 로고    scopus 로고
    • Extensive personal human gut microbiota culture collections characterized and manipulated in gnotobiotic mice
    • Goodman A. Kallstrom G. Faith J. Reyes A. Moore A. Dantas G. et al. (2011) Extensive personal human gut microbiota culture collections characterized and manipulated in gnotobiotic mice. Proc Natl Acad Sci U S A 108: 6252–6257.
    • (2011) Proc Natl Acad Sci U S A , vol.108 , pp. 6252-6257
    • Goodman, A.1    Kallstrom, G.2    Faith, J.3    Reyes, A.4    Moore, A.5    Dantas, G.6
  • 22
    • 0030977050 scopus 로고    scopus 로고
    • Exchange of glutamate and gamma-aminobutyrate in a Lactobacillus strain
    • Higuchi T. Hayashi H. Abe K. (1997) Exchange of glutamate and gamma-aminobutyrate in a Lactobacillus strain. J Bacteriol 179: 3362–3364.
    • (1997) J Bacteriol , vol.179 , pp. 3362-3364
    • Higuchi, T.1    Hayashi, H.2    Abe, K.3
  • 23
    • 79957714527 scopus 로고    scopus 로고
    • Regulation of innate and adaptive immunity by the commensal microbiota
    • Jarchum I. Pamer E. (2011) Regulation of innate and adaptive immunity by the commensal microbiota. Curr Opin Immunol 23: 353–360.
    • (2011) Curr Opin Immunol , vol.23 , pp. 353-360
    • Jarchum, I.1    Pamer, E.2
  • 24
    • 62149117549 scopus 로고    scopus 로고
    • Probiotic Lactobacillus reuteri biofilms produce antimicrobial and anti-inflammatory factors
    • Jones S. Versalovic J. (2009) Probiotic Lactobacillus reuteri biofilms produce antimicrobial and anti-inflammatory factors. BMC Microbiol 9: 35.
    • (2009) BMC Microbiol , vol.9 , pp. 35
    • Jones, S.1    Versalovic, J.2
  • 25
    • 79959467647 scopus 로고    scopus 로고
    • Energy-balance studies reveal associations between gut microbes, caloric load, and nutrient absorption in humans
    • Jumpertz R. Le D. Turnbaugh P. Trinidad C. Bogardus C. Gordon J. et al. (2011) Energy-balance studies reveal associations between gut microbes, caloric load, and nutrient absorption in humans. Am J Clin Nutr 94: 58–65.
    • (2011) Am J Clin Nutr , vol.94 , pp. 58-65
    • Jumpertz, R.1    Le, D.2    Turnbaugh, P.3    Trinidad, C.4    Bogardus, C.5    Gordon, J.6
  • 26
    • 30944450776 scopus 로고    scopus 로고
    • Inhibitory effects of Lactobacillus reuteri on visceral pain induced by colorectal distension in Sprague–Dawley rats
    • Kamiya T. Wang L. Forsythe P. Goettsche G. Mao Y. Wang Y. et al. (2006) Inhibitory effects of Lactobacillus reuteri on visceral pain induced by colorectal distension in Sprague–Dawley rats. Gut 55: 191–196.
    • (2006) Gut , vol.55 , pp. 191-196
    • Kamiya, T.1    Wang, L.2    Forsythe, P.3    Goettsche, G.4    Mao, Y.5    Wang, Y.6
  • 27
    • 32944474237 scopus 로고    scopus 로고
    • Innate immunity gone awry: linking microbial infections to chronic inflammation and cancer
    • Karin M. Lawrence T. Nizet V. (2006) Innate immunity gone awry: linking microbial infections to chronic inflammation and cancer. Cell 124: 823–835.
    • (2006) Cell , vol.124 , pp. 823-835
    • Karin, M.1    Lawrence, T.2    Nizet, V.3
  • 28
    • 84857039944 scopus 로고    scopus 로고
    • The effect of a multispecies probiotic mixture on the symptoms and fecal microbiota in diarrhea-dominant irritable bowel syndrome: a randomized, double-blind, placebo-controlled trial
    • Ki Cha B. Mun Jung S. Hwan Choi C. Song I. Woong Lee H. Joon Kim H. et al. (2011) The effect of a multispecies probiotic mixture on the symptoms and fecal microbiota in diarrhea-dominant irritable bowel syndrome: a randomized, double-blind, placebo-controlled trial. J Clin Gastroenterol 46: 220–227.
    • (2011) J Clin Gastroenterol , vol.46 , pp. 220-227
    • Ki Cha, B.1    Mun Jung, S.2    Hwan Choi, C.3    Song, I.4    Woong Lee, H.5    Joon Kim, H.6
  • 29
    • 38449088143 scopus 로고    scopus 로고
    • Comparative metagenomics revealed commonly enriched gene sets in human gut microbiomes
    • Kurokawa K. Itoh T. Kuwahara T. Oshima K. Toh H. Toyoda A. et al. (2007) Comparative metagenomics revealed commonly enriched gene sets in human gut microbiomes. DNA Res 14: 169–181.
    • (2007) DNA Res , vol.14 , pp. 169-181
    • Kurokawa, K.1    Itoh, T.2    Kuwahara, T.3    Oshima, K.4    Toh, H.5    Toyoda, A.6
  • 31
    • 84863718303 scopus 로고    scopus 로고
    • Analysis of gut microbial regulation of host gene expression along the length of the gut and regulation of gut microbial ecology through Myd 88
    • Larsson E. Tremaroli V. Lee Y. Koren O. Nookaew I. Fricker A. et al. (2012) Analysis of gut microbial regulation of host gene expression along the length of the gut and regulation of gut microbial ecology through Myd 88. Gut, 61: 1124–1131.
    • (2012) Gut , vol.61 , pp. 1124-1131
    • Larsson, E.1    Tremaroli, V.2    Lee, Y.3    Koren, O.4    Nookaew, I.5    Fricker, A.6
  • 32
    • 77749322389 scopus 로고    scopus 로고
    • A novel probiotic mixture exerts a therapeutic effect on experimental autoimmune encephalomyelitis mediated by IL-10 producing regulatory T cells
    • Lavasani S. Dzhambazov B. Nouri M. Fak F. Buske S. Molin G. et al. (2010) A novel probiotic mixture exerts a therapeutic effect on experimental autoimmune encephalomyelitis mediated by IL-10 producing regulatory T cells. PloS ONE 5: e9009.
    • (2010) PloS ONE , vol.5 , pp. e9009
    • Lavasani, S.1    Dzhambazov, B.2    Nouri, M.3    Fak, F.4    Buske, S.5    Molin, G.6
  • 33
    • 23044526646 scopus 로고    scopus 로고
    • ‘Ome sweet’ omics: a genealogical treasury of words
    • Lederberg J. McCray A. (2001) ‘Ome sweet’ omics: a genealogical treasury of words. The Scientist 15: 8.
    • (2001) The Scientist , vol.15 , pp. 8
    • Lederberg, J.1    McCray, A.2
  • 34
    • 80054939521 scopus 로고    scopus 로고
    • Irritable bowel syndrome, gut microbiota and probiotics
    • Lee B. Bak Y. (2011) Irritable bowel syndrome, gut microbiota and probiotics. J Neurogastroenterol Motil 17: 252–266.
    • (2011) J Neurogastroenterol Motil , vol.17 , pp. 252-266
    • Lee, B.1    Bak, Y.2
  • 35
    • 78449276921 scopus 로고    scopus 로고
    • Lactic acid bacterial cell factories for gamma-aminobutyric acid
    • Li H. Cao Y. (2010) Lactic acid bacterial cell factories for gamma-aminobutyric acid. Amino Acids 39: 1107–1116.
    • (2010) Amino Acids , vol.39 , pp. 1107-1116
    • Li, H.1    Cao, Y.2
  • 36
    • 49749119520 scopus 로고    scopus 로고
    • Probiotic Lactobacillus reuteri suppress proinflammatory cytokines via c-Jun
    • Lin Y. Thibodeaux C. Pena J. Ferry G. Versalovic J. (2008) Probiotic Lactobacillus reuteri suppress proinflammatory cytokines via c-Jun. Inflamm Bowel Dis 14: 1068–1083.
    • (2008) Inflamm Bowel Dis , vol.14 , pp. 1068-1083
    • Lin, Y.1    Thibodeaux, C.2    Pena, J.3    Ferry, G.4    Versalovic, J.5
  • 37
    • 78149484054 scopus 로고    scopus 로고
    • Human-derived probiotic Lactobacillus reuteri strains differentially reduce intestinal inflammation
    • Liu Y. Fatheree N. Mangalat N. Rhoads J. (2010) Human-derived probiotic Lactobacillus reuteri strains differentially reduce intestinal inflammation. Am J Physiol Gastrointest Liver Physiol 299: G1087–G1096.
    • (2010) Am J Physiol Gastrointest Liver Physiol , vol.299 , pp. G1087-G1096
    • Liu, Y.1    Fatheree, N.2    Mangalat, N.3    Rhoads, J.4
  • 38
    • 74249088146 scopus 로고    scopus 로고
    • Gut commensal Lactobacillus reuteri 100–23 stimulates an immunoregulatory response
    • Livingston M. Loach D. Wilson M. Tannock G. Baird M. (2009) Gut commensal Lactobacillus reuteri 100–23 stimulates an immunoregulatory response. Immunol Cell Biol 88: 99–102.
    • (2009) Immunol Cell Biol , vol.88 , pp. 99-102
    • Livingston, M.1    Loach, D.2    Wilson, M.3    Tannock, G.4    Baird, M.5
  • 39
    • 30944466824 scopus 로고    scopus 로고
    • Reduced diversity of faecal microbiota in Crohn's disease revealed by a metagenomic approach
    • Manichanh C. Rigottier-Gois L. Bonnaud E. Gloux K. Pelletier E. Frangeul L. et al. (2006) Reduced diversity of faecal microbiota in Crohn's disease revealed by a metagenomic approach. Gut 55: 205–211.
    • (2006) Gut , vol.55 , pp. 205-211
    • Manichanh, C.1    Rigottier-Gois, L.2    Bonnaud, E.3    Gloux, K.4    Pelletier, E.5    Frangeul, L.6
  • 40
    • 79960645242 scopus 로고    scopus 로고
    • Gut feelings: the emerging biology of gut–brain communication
    • Mayer E. (2011) Gut feelings: the emerging biology of gut–brain communication. Nat Rev Neurosci 12: 453–466.
    • (2011) Nat Rev Neurosci , vol.12 , pp. 453-466
    • Mayer, E.1
  • 41
    • 80054960299 scopus 로고    scopus 로고
    • The impact of a consortium of fermented milk strains on the gut microbiome of gnotobiotic mice and monozygotic twins
    • McNulty N. Yatsunenko T. Hsiao A. Faith J. Muegge B. Goodman A. et al. (2011) The impact of a consortium of fermented milk strains on the gut microbiome of gnotobiotic mice and monozygotic twins. Sci Transl Med 3: 106.
    • (2011) Sci Transl Med , vol.3 , pp. 106
    • McNulty, N.1    Yatsunenko, T.2    Hsiao, A.3    Faith, J.4    Muegge, B.5    Goodman, A.6
  • 43
    • 67749120075 scopus 로고    scopus 로고
    • Effects of gut microbiota on the brain: implications for psychiatry
    • Neufeld K. Foster J. (2009) Effects of gut microbiota on the brain: implications for psychiatry. J Psychiatry Neurosci 34: 230–231.
    • (2009) J Psychiatry Neurosci , vol.34 , pp. 230-231
    • Neufeld, K.1    Foster, J.2
  • 44
    • 0034059773 scopus 로고    scopus 로고
    • Alteration of intestinal microflora is associated with reduction in abdominal bloating and pain in patients with irritable bowel syndrome
    • Nobaek S. Johansson M. Molin G. Ahrne S. Jeppsson B. (2000) Alteration of intestinal microflora is associated with reduction in abdominal bloating and pain in patients with irritable bowel syndrome. Am J Gastroenterol 95: 1231–1238.
    • (2000) Am J Gastroenterol , vol.95 , pp. 1231-1238
    • Nobaek, S.1    Johansson, M.2    Molin, G.3    Ahrne, S.4    Jeppsson, B.5
  • 45
    • 83655201459 scopus 로고    scopus 로고
    • Production of bioactive substances by intestinal bacteria as a basis for explaining probiotic mechanisms: bacteriocins and conjugated linoleic acid
    • O'Shea E. Cotter P. Stanton C. Ross R. Hill C. (2011) Production of bioactive substances by intestinal bacteria as a basis for explaining probiotic mechanisms: bacteriocins and conjugated linoleic acid. Int J Food Microbiol 152: 189–205.
    • (2011) Int J Food Microbiol , vol.152 , pp. 189-205
    • O'Shea, E.1    Cotter, P.2    Stanton, C.3    Ross, R.4    Hill, C.5
  • 46
    • 75349111165 scopus 로고    scopus 로고
    • Probiotic bacteria influence the composition and function of the intestinal microbiota
    • O'Toole P. Cooney J. (2008) Probiotic bacteria influence the composition and function of the intestinal microbiota. Interdiscip Perspect Infect Dis 2008: 175–285.
    • (2008) Interdiscip Perspect Infect Dis , vol.2008 , pp. 175-285
    • O'Toole, P.1    Cooney, J.2
  • 47
    • 79952497372 scopus 로고    scopus 로고
    • Gut, bugs, and brain: role of commensal bacteria in the control of central nervous system disease
    • Ochoa-Reparaz J. Mielcarz D. Begum-Haque S. Kasper L. (2011) Gut, bugs, and brain: role of commensal bacteria in the control of central nervous system disease. Ann Neurol 69: 240–247.
    • (2011) Ann Neurol , vol.69 , pp. 240-247
    • Ochoa-Reparaz, J.1    Mielcarz, D.2    Begum-Haque, S.3    Kasper, L.4
  • 48
    • 77249096486 scopus 로고    scopus 로고
    • Role of gut commensal microflora in the development of experimental autoimmune encephalomyelitis
    • Ochoa-Reparaz J. Mielcarz D. Ditrio L. Burroughs A. Foureau D. Haque-Begum S. et al. (2009) Role of gut commensal microflora in the development of experimental autoimmune encephalomyelitis. J Immunol 183: 6041–6050.
    • (2009) J Immunol , vol.183 , pp. 6041-6050
    • Ochoa-Reparaz, J.1    Mielcarz, D.2    Ditrio, L.3    Burroughs, A.4    Foureau, D.5    Haque-Begum, S.6
  • 49
    • 0345868847 scopus 로고    scopus 로고
    • Genotypic and phenotypic studies of murine intestinal Lactobacilli: species differences in mice with and without colitis
    • Pena J. Li S. Wilson P. Thibodeau S. Szary A. Versalovic J. (2004) Genotypic and phenotypic studies of murine intestinal Lactobacilli: species differences in mice with and without colitis. Appl Environ Microbiol 70: 558–568.
    • (2004) Appl Environ Microbiol , vol.70 , pp. 558-568
    • Pena, J.1    Li, S.2    Wilson, P.3    Thibodeau, S.4    Szary, A.5    Versalovic, J.6
  • 50
    • 12844260840 scopus 로고    scopus 로고
    • Probiotic Lactobacillus spp. diminish helicobacter hepaticus-induced inflammatory bowel disease in interleukin-10-deficient mice
    • Pena J. Rogers A. Ge Z. Ng V. Li S. Fox J. et al. (2005) Probiotic Lactobacillus spp. diminish helicobacter hepaticus-induced inflammatory bowel disease in interleukin-10-deficient mice. Infect Immun 73: 912–920.
    • (2005) Infect Immun , vol.73 , pp. 912-920
    • Pena, J.1    Rogers, A.2    Ge, Z.3    Ng, V.4    Li, S.5    Fox, J.6
  • 51
    • 84863413720 scopus 로고    scopus 로고
    • A high-fat diet is associated with endotoxemia that originates from the gut
    • Pendyala S. Walker J. Holt P. (2012) A high-fat diet is associated with endotoxemia that originates from the gut. Gastroenterology 142: 1100–1101.e2.
    • (2012) Gastroenterology , vol.142 , pp. 1100-1101.e2
    • Pendyala, S.1    Walker, J.2    Holt, P.3
  • 52
    • 0001874689 scopus 로고    scopus 로고
    • Ecological resilience, biodiversity, and scale
    • Peterson G. Allen C. Holling C. (1998) Ecological resilience, biodiversity, and scale. Ecosystems 1: 6–18.
    • (1998) Ecosystems , vol.1 , pp. 6-18
    • Peterson, G.1    Allen, C.2    Holling, C.3
  • 53
    • 84856901973 scopus 로고    scopus 로고
    • Human microbiome in health and disease
    • Pflughoeft K. Versalovic J. (2012) Human microbiome in health and disease. Annu Rev Pathol 7: 99–122.
    • (2012) Annu Rev Pathol , vol.7 , pp. 99-122
    • Pflughoeft, K.1    Versalovic, J.2
  • 54
    • 84860910895 scopus 로고    scopus 로고
    • Probiotics stimulate enterocyte migration and microbial diversity in the neonatal mouse intestine
    • Preidis G. Saulnier D. Blutt S. Mistretta T. Riehle K. Major A. et al. (2012) Probiotics stimulate enterocyte migration and microbial diversity in the neonatal mouse intestine. FASEB J 26: 1960–1969.
    • (2012) FASEB J , vol.26 , pp. 1960-1969
    • Preidis, G.1    Saulnier, D.2    Blutt, S.3    Mistretta, T.4    Riehle, K.5    Major, A.6
  • 55
    • 65449125343 scopus 로고    scopus 로고
    • Targeting the human microbiome with antibiotics, probiotics, and prebiotics: gastroenterology enters the metagenomics era
    • Preidis G. Versalovic J. (2009) Targeting the human microbiome with antibiotics, probiotics, and prebiotics: gastroenterology enters the metagenomics era. Gastroenterology 136: 2015–2031.
    • (2009) Gastroenterology , vol.136 , pp. 2015-2031
    • Preidis, G.1    Versalovic, J.2
  • 56
    • 77950251400 scopus 로고    scopus 로고
    • A human gut microbial gene catalogue established by metagenomic sequencing
    • Qin J. Li R. Raes J. Arumugam M. Burgdorf K. Manichanh C. et al. (2010) A human gut microbial gene catalogue established by metagenomic sequencing. Nature 464: 59–65.
    • (2010) Nature , vol.464 , pp. 59-65
    • Qin, J.1    Li, R.2    Raes, J.3    Arumugam, M.4    Burgdorf, K.5    Manichanh, C.6
  • 57
    • 79955718307 scopus 로고    scopus 로고
    • Exploring metabolic pathway reconstruction and genome-wide expression profiling in Lactobacillus reuteri to define functional probiotic features
    • Saulnier D. Santos F. Roos S. Mistretta T. Spinler J. Molenaar D. et al. (2011) Exploring metabolic pathway reconstruction and genome-wide expression profiling in Lactobacillus reuteri to define functional probiotic features. PloS ONE 6: e18783.
    • (2011) PloS ONE , vol.6 , pp. e18783
    • Saulnier, D.1    Santos, F.2    Roos, S.3    Mistretta, T.4    Spinler, J.5    Molenaar, D.6
  • 59
    • 79954547410 scopus 로고    scopus 로고
    • Community health care: therapeutic opportunities in the human microbiome
    • Sonnenburg J. Fischbach M. (2011) Community health care: therapeutic opportunities in the human microbiome. Sci Transl Med 3: 78ps12.
    • (2011) Sci Transl Med , vol.3 , pp. 78ps12
    • Sonnenburg, J.1    Fischbach, M.2
  • 60
    • 44649149490 scopus 로고    scopus 로고
    • Human-derived probiotic Lactobacillus reuteri demonstrate antimicrobial activities targeting diverse enteric bacterial pathogens
    • Spinler J. Taweechotipatr M. Rognerud C. Ou C. Tumwasorn S. Versalovic J. (2008) Human-derived probiotic Lactobacillus reuteri demonstrate antimicrobial activities targeting diverse enteric bacterial pathogens. Anaerobe 14: 166–171.
    • (2008) Anaerobe , vol.14 , pp. 166-171
    • Spinler, J.1    Taweechotipatr, M.2    Rognerud, C.3    Ou, C.4    Tumwasorn, S.5    Versalovic, J.6
  • 61
    • 80052197161 scopus 로고    scopus 로고
    • Contribution of glutamate decarboxylase in Lactobacillus reuteri to acid resistance and persistence in sourdough fermentation
    • Su M. Schlicht S. Ganzle M. (2011) Contribution of glutamate decarboxylase in Lactobacillus reuteri to acid resistance and persistence in sourdough fermentation. Microb Cell Fact 10(Suppl. 1): S8.
    • (2011) Microb Cell Fact , vol.10 , Issue.Suppl. 1 , pp. S8
    • Su, M.1    Schlicht, S.2    Ganzle, M.3
  • 62
    • 84862276328 scopus 로고    scopus 로고
    • The Human Microbiome Project Consortium
    • Structure, function and diversity of the healthy human microbiome
    • The Human Microbiome Project Consortium (2012 a) Structure, function and diversity of the healthy human microbiome. Nature 486: 207–214.
    • (2012) Nature , vol.486 , pp. 207-214
  • 63
    • 84862286169 scopus 로고    scopus 로고
    • The Human Microbiome Project Consortium
    • A framework for human microbiome research
    • The Human Microbiome Project Consortium (2012 b) A framework for human microbiome research. Nature 486: 215–221.
    • (2012) Nature , vol.486 , pp. 215-221
  • 64
    • 84857469966 scopus 로고    scopus 로고
    • Histamine derived from probiotic Lactobacillus reuteri suppresses TNF via modulation of Pka and Erk signaling
    • Thomas C. Hong T. van Pijkeren J. Hemarajata P. Trinh D. Hu W. et al. (2012) Histamine derived from probiotic Lactobacillus reuteri suppresses TNF via modulation of Pka and Erk signaling. PloS ONE 7: e31951.
    • (2012) PloS ONE , vol.7 , pp. e31951
    • Thomas, C.1    Hong, T.2    van Pijkeren, J.3    Hemarajata, P.4    Trinh, D.5    Hu, W.6
  • 65
    • 77954832198 scopus 로고    scopus 로고
    • Probiotics-host communication: modulation of signaling pathways in the intestine
    • Thomas C. Versalovic J. (2010) Probiotics-host communication: modulation of signaling pathways in the intestine. Gut Microbes 1: 148–163.
    • (2010) Gut Microbes , vol.1 , pp. 148-163
    • Thomas, C.1    Versalovic, J.2
  • 67
    • 2342449224 scopus 로고    scopus 로고
    • Colonization and immunomodulation by Lactobacillus reuteri ATCC 55730 in the human gastrointestinal tract
    • Valeur N. Engel P. Carbajal N. Connolly E. Ladefoged K. (2004) Colonization and immunomodulation by Lactobacillus reuteri ATCC 55730 in the human gastrointestinal tract. Appl Environ Microbiol 70: 1176–1181.
    • (2004) Appl Environ Microbiol , vol.70 , pp. 1176-1181
    • Valeur, N.1    Engel, P.2    Carbajal, N.3    Connolly, E.4    Ladefoged, K.5
  • 68
    • 79952749581 scopus 로고    scopus 로고
    • Human mucosal in vivo transcriptome responses to three Lactobacilli indicate how probiotics may modulate human cellular pathways
    • van Baarlen P. Troost F. van der Meer C. Hooiveld G. Boekschoten M. Brummer R. et al. (2010) Human mucosal in vivo transcriptome responses to three Lactobacilli indicate how probiotics may modulate human cellular pathways. Proc Natl Acad Sci U S A 108(Suppl. 1): 4562–4569.
    • (2010) Proc Natl Acad Sci U S A , vol.108 , Issue.Suppl. 1 , pp. 4562-4569
    • van Baarlen, P.1    Troost, F.2    van der Meer, C.3    Hooiveld, G.4    Boekschoten, M.5    Brummer, R.6
  • 69
    • 80051856839 scopus 로고    scopus 로고
    • The human gut microbiome: ecology and recent evolutionary changes
    • Walter J. Ley R. (2011) The human gut microbiome: ecology and recent evolutionary changes. Annu Rev Microbiol 65: 411–429.
    • (2011) Annu Rev Microbiol , vol.65 , pp. 411-429
    • Walter, J.1    Ley, R.2
  • 70
    • 62649151803 scopus 로고    scopus 로고
    • Metabolomics analysis reveals large effects of gut microflora on mammalian blood metabolites
    • Wikoff W. Anfora A. Liu J. Schultz P. Lesley S. Peters E. et al. (2009) Metabolomics analysis reveals large effects of gut microflora on mammalian blood metabolites. Proc Natl Acad Sci U S A 106: 3698–3703.
    • (2009) Proc Natl Acad Sci U S A , vol.106 , pp. 3698-3703
    • Wikoff, W.1    Anfora, A.2    Liu, J.3    Schultz, P.4    Lesley, S.5    Peters, E.6
  • 71
    • 80053618114 scopus 로고    scopus 로고
    • Linking long-term dietary patterns with gut microbial enterotypes
    • Wu G. Chen J. Hoffmann C. Bittinger K. Chen Y. Keilbaugh S. et al. (2011) Linking long-term dietary patterns with gut microbial enterotypes. Science 334: 105–108.
    • (2011) Science , vol.334 , pp. 105-108
    • Wu, G.1    Chen, J.2    Hoffmann, C.3    Bittinger, K.4    Chen, Y.5    Keilbaugh, S.6
  • 72
    • 57149094667 scopus 로고    scopus 로고
    • NKT cell-dependent amelioration of a mouse model of multiple sclerosis by altering gut flora
    • Yokote H. Miyake S. Croxford J. Oki S. Mizusawa H. Yamamura T. (2008) NKT cell-dependent amelioration of a mouse model of multiple sclerosis by altering gut flora. Am J Pathol 173: 1714–1723.
    • (2008) Am J Pathol , vol.173 , pp. 1714-1723
    • Yokote, H.1    Miyake, S.2    Croxford, J.3    Oki, S.4    Mizusawa, H.5    Yamamura, T.6
  • 73
    • 38549166401 scopus 로고    scopus 로고
    • Lactic acid bacterial colonization and human rotavirus infection influence distribution and frequencies of monocytes/macrophages and dendritic cells in neonatal gnotobiotic pigs
    • Zhang W. Wen K. Azevedo M. Gonzalez A. Saif L. Li G. et al. (2008) Lactic acid bacterial colonization and human rotavirus infection influence distribution and frequencies of monocytes/macrophages and dendritic cells in neonatal gnotobiotic pigs. Vet Immunol Immunopathol 121: 222–231.
    • (2008) Vet Immunol Immunopathol , vol.121 , pp. 222-231
    • Zhang, W.1    Wen, K.2    Azevedo, M.3    Gonzalez, A.4    Saif, L.5    Li, G.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.