Biopiracy versus One-World Medicine–From colonial relicts to global collaborative concepts

Phytomedicine

Volumn 53, Issue , 2019, Pages 319-331

  Efferth, Thomas ^a   Banerjee, Mita ^a   Abu Darwish, Mohammad Sanad ^a,b   Abdelfatah, Sara ^a   Böckers, Madeleine ^a   Bhakta Guha, Dipita ^c   Bolzani, Vanderlan ^d   Daak, Salah ^e   Demirezer, Ömür Lutfiye ^f   Dawood, Mona ^a   Efferth, Monika ^a   El Seedi, Hesham R ^g,h   Fischer, Nicolas ^a   Greten, Henry J ^i,j   Hamdoun, Sami ^a   Hong, Chunlan ^a   Horneber, Markus ^k   Kadioglu, Onat ^a   Khalid, Hassan E ^l   Khalid, Sami A ^l,m   Kuete, Victor ⁿ   Mahmoud, Nuha ^a   Marin, José ^o   Mbaveng, Armelle ⁿ   Midiwo, Jacob ^p   Nakagawa, Hiroshi ^q   Naß, Janine ^a   Ngassapa, Olipa ^r   Ochwang'i, Dominic ^p   Omosa, Leonida K ^p   Ooko, Edna A ^a   Özenver, Nadire ^a,f   Poornima, Paramasivan ^s   Romero, Marta Rodriguez ^o   Saeed, Mohamed E M ^a   Salgueiro, Ligia ^t   Seo, Ean Jeong ^a   Yan, Ge ^a   Yasin, Zahir ^u   Saeed, Elfatih M ^v   Paul, Norbert W ^w   more..

^a JOHANNES GUTENBERG UNIVERSITY   (Germany)

^b AL BALQA APPLIED UNIVERSITY   (Jordan)

^c SASTRA UNIVERSITY   (India)

^d SÃO PAULO STATE UNIVERSITY UNESP   (Brazil)

^e Dr Salah Wanesi Foundation for Cancer Research and Control   (Sudan)

^f HACETTEPE UNIVERSITY   (Turkey)

^g UNIVERSITY OF MALAYA   (Malaysia)

^h UPPSALA UNIVERSITY   (Sweden)

ⁱ UNIVERSITY OF PORTO   (Portugal)

^j Heidelberg School of Chinese Medicine   (Germany)

^k KLINIKUM NÜRNBERG   (Germany)

^l UNIVERSITY OF KHARTOUM   (Sudan)

^m University of Science and Technology   (Sudan)

ⁿ UNIVERSITY OF DSCHANG   (Cameroon)

^o UNIVERSITY OF SALAMANCA   (Spain)

^p UNIVERSITY OF NAIROBI   (Kenya)

^q CHUBU UNIVERSITY   (Japan)

^r MUHIMBILI UNIVERSITY OF HEALTH AND ALLIED SCIENCES   (Tanzania)

^s UNIVERSITY OF ABERTAY DUNDEE   (United Kingdom)

^t UNIVERSITY OF COIMBRA   (Portugal)

^u Tayba Cancer Centre   (Sudan)

^v Sudan National Government   (Sudan)

^w UNIVERSITY MEDICAL CENTER MAINZ   (Germany)

more..

Author keywords

Complementary and alternative medicine; Evidence based medicine; Integrative medicine; Nagoya protocol; Quality control; Traditional medicine

Indexed keywords

HERBACEOUS AGENT; NON PRESCRIPTION DRUG; PHYTOCHEMICAL;

ALTERNATIVE MEDICINE; BIOPIRACY; BIOPROSPECTING; CLINICAL TRIAL (TOPIC); COLONIALISM; DEVELOPED COUNTRY; DEVELOPING COUNTRY; EDUCATION PROGRAM; EUROPEAN UNION; EVIDENCE BASED MEDICINE; HERB DRUG INTERACTION; HUMAN; INDIGENOUS PEOPLE; INFORMATION CENTER; INTEGRATIVE MEDICINE; KNOWLEDGE; LAW; MEDICINAL PLANT; PRESCRIPTION; PRIMARY HEALTH CARE; PRIORITY JOURNAL; QUALITY CONTROL; REFERENCE DATABASE; REVIEW; STANDARDIZATION; TRADITIONAL MEDICINE; UNITED NATIONS; BIODIVERSITY; DOUBLE BLIND PROCEDURE; INTERNATIONAL COOPERATION; PATENT; SELF MEDICATION; STANDARDS; THEFT;

BIODIVERSITY; COLONIALISM; COMPLEMENTARY THERAPIES; DEVELOPING COUNTRIES; DOUBLE-BLIND METHOD; EUROPEAN UNION; EVIDENCE-BASED MEDICINE; HUMANS; INTERNATIONAL COOPERATION; MEDICINE, TRADITIONAL; NATUROPATHY; PATENTS AS TOPIC; PLANTS, MEDICINAL; QUALITY CONTROL; SELF MEDICATION; THEFT;

EID: 85052799680     PISSN: 09447113     EISSN: 1618095X     Source Type: Journal    
DOI: 10.1016/j.phymed.2018.06.007     Document Type: Review

References (152)

1. Abuja Declaration of the African Summit of Heads of State and Government of April 2001 on research on traditional medicines used for the treatment of malaria, TB, HIV/Aids and other infectious diseases as a priority. http://www.un.org/ga/aids/pdf/abuja_declaration.pdf (Accessed17 June 2017).
2. Agbabiaka, T., Wider, B., Watson, L.K., Goodman, C., Concurrent use of prescription drugs and herbal medicinal products in older adults: a systematic review protocol. Syst. Rev., 5, 2016, 65.
3. Albrecht, H., [The situation of complementary medicine in Germany]. [Article in German]. Forsch. Komplementmed 20 (2013), 73–77.
4. Anyinam, C., Availability, accessibility, acceptability and adaptability: four attributes of African ethnomedicine. Soc. Sci. Med. 25 (1987), 803–811.
5. Awodele, O., Agbajea, E.O., Abiolaa, O.O., Awodeleb, D.F., Dolapoc, D.C., Doctors’ attitudes towards the use of herbal medicine in Lagos, Nigeria. J. Herbal Med. 2 (2012), 16–22.
6. Aziato, L., Antwi, H.O., Facilitators and barriers of herbal medicine use in Accra, Ghana: an inductive exploratory study. BMC Complement. Alternat. Med., 16, 2016, 142.
7. Babu, P.A., Suneetha, G., Boddepalli, R., Lakshmi, V.V., Rani, T.S., Rambabu, Y., Srinivas, K., A database of 389 medicinal plants for diabetes. Bioinformation 1 (2006), 130–131.
8. Barimah, K.B., Traditional healers as service providers in Ghana's National Health Insurance Scheme: the wrong way forward?. Global Public Health 8 (2013), 202–208.
9. Bellakhdr, J., La Pharmacopee Marocaine Traditionnelle: Medecine Arabe Ancienne et Saviors Populaires. 1997, Ibis Press, Paris, 764.
10. Bent, S., Ko, R., Commonly used herbal medicines in the United States: a review. Am. J. Med. 116 (2004), 478–485.
11. Berman, B.M., Swyers, J.P., Kuczmarczyk, J., Complementary and alternative medicine: herbal therapies for diabetes. J. Assoc. Acad. Mino. Phys. 10 (1999), 10–14.
12. Bodeker, G., Lessons on integration from the developing world's experience. Br. Med. J. 322 (2001), 164–167.
13. Booker, A., Jalil, B., Frommenwiler, D., Reich, E., Zhai, L., Kulic, Z., Heinrich, M., The authenticity and quality of Rhodiola rosea products. Phytomedicine 23 (2016), 754–762.
14. Brinkhaus, B., Witt, C.M., Jena, S., Bockelbrink, A., Ortiz, M., Willich, S.N., Integration of complementary and alternative medicine into medical schools in Austria, Germany and Switzerland - results of a cross-sectional study. Wien. Med. Wochenschr. 161 (2011), 32–43.
15. Bruce, J.C., Marrying modern herbal practices and technology with traditional practices: issues for the African continent. Int. Nur. Rev. 49 (2002), 161–167.
16. Buell, L., The Environmental Imagination: Thoreau, Nature Writing and the Formation of American Culture. 1995, Harvard UP, Cambridge.
17. Busato, A., Eichenberger, R., Künzi, B., Extent and structure of health insurance expenditures for complementary and alternative medicine in Swiss primary care. BMC Health Serv. Res., 6, 2006, 132.
18. Busia, K., Medical provision in Africa - past and present. Phytother. Res. 19 (2005), 919–923.
19. Cavaliere, C., The effects of climate change on medicinal and aromatic plants. HerbalGram 81 (2009), 44–57.
20. Chen, F.P., Chen, T.J., Kung, Y.Y., Chen, Y.C., Chou, L.F., Chen, F.J., Hwang, S.J., Use frequency of traditional Chinese medicine in Taiwan. BMC Health Serv. Res., 7, 2007, 26.
21. Choi, J.G., Eom, S.M., Kim, J., Kim, S.H., Huh, E., Kim, H., Lee, Y., Lee, H., Oh, M.S., A comprehensive review of recent studies on herb-drug interaction: a focus on pharmacodynamic interaction. J. Altern. Complement. Med. 22 (2016), 262–279.
22. Chung, V.C., Ma, P.H., Wang, H.H., Wang, J.J., Hong, L.C., Wei, X., Wong, S.Y., Tang, J.L., Griffiths, S.M., Integrating traditional Chinese medicine services in community health centers: insights into utilization patterns in the Pearl River region of China. Evid. Based Complement. Alternat. Med., 2013, 2013, 426360.
23. Consolini, A.E., Ragone, M.I., Patterns of self-medication with medicinal plants and related adverse events–a South American survey. Curr. Drug Safety 5 (2010), 333–341.
24. Cragg, G.M., Grothaus, P.G., Newman, D.J., New horizons for old drugs and drug leads. J. Nat. Prod. 77 (2014), 703–723.
25. Dai, G., Jiang, Z., Bai, Y., Zhang, Q., Zhu, L., Bai, X., Ju, W., Pan, R., Pharmacokinetic herb-drug interaction of Xuesaitong dispersible tablet and aspirin after oral administration in blood stasis model rats. Phytomedicine 26 (2017), 62–68.
26. Dang, H., Wang, Q., Wang, H., Yan, M., Liu, X., The integration of Chinese Materia Medica into the Chinese health care delivery system, an update. Phytother. Res. 30 (2016), 292–297.
27. de Jong, Y., Kouwenberg, J., Boumans, L., Hussey, C., Hyam, R., Nicolson, N., Kirk, P., Paton, A., Michel, E., Guiry, M.D., Boegh, P.S., Pedersen, H.A.E., Enghoff, H., von Raab-Straube, E., Guntsch, A, Geoffroy, M., et al. PESI - a taxonomic backbone for Europe. Biodivers. Data J., 3, 2015, e5848.
28. De Loughrey, E., Handley, G., Postcolonial Ecologies: Literatures of the Environment. 2011, Oxford UP, Oxford.
29. Delabays, N., Simonnet, X., Gaudin, M., The genetics of artemisinin content in Artemisia annua L. and the breeding of high yielding cultivars. Curr. Med. Chem. 8 (2001), 1795–1801.
30. Economic Commission for Africa. Economic and Social Conditions in Southern Africa in 2007. http://repository.uneca.org/bitstream/handle/10855/3574/Bib.%2028555_I.pdf?sequence=1, 2008 (Accessed 17 June 2017).
31. Efferth, T., Personalized cancer medicine: from molecular diagnostics to targeted therapy with natural products. Planta Med 76 (2010), 1143–1154.
32. Efferth, T., Perspectives for globalized natural medicines in the 21st century. Chin. J. Nat. Med. 9 (2011), 1–6.
33. Efferth, T., Stem cells, cancer stem-like cells, and natural products. Planta Med. 78 (2012), 935–942.
34. Efferth, T., Greten, H.J., Medicinal and aromatic plant research in the 21st century. Med. Aromat. Plants, 1, 2012, e110.
35. Efferth, T., Greten, H.J., Autophagy by natural products in cancer cells. Biochem. Anal. Biochem., 1, 2012, 8.
36. Efferth, T., Greten, H.J., Quality control for medicinal plants. Med. Aromat. Plants (Los Angeles), 1, 2012, 7.
37. Efferth, T., Greten, H.J., The European directive on traditional herbal medicinal products: friend or foe for plant-based therapies?. Zhong Xi Yi Jie He Xue Bao 10 (2012), 357–361.
38. Efferth, T., Kaina, B., Toxicities by herbal medicines with emphasis to traditional Chinese medicine. Curr. Drug Metab. 12 (2011), 989–996.
39. Efferth, T., Koch, E., Complex interactions between phytochemicals. The multi-target therapeutic concept of phytotherapy. Curr. Drug Targets 12 (2011), 122–132.
40. Efferth, T., Banerjee, M., Paul, N.W., Abdelfatah, S., Arend, J., Elhassan, G., Hamdoun, S., Hamm, R., Hong, C., Kadioglu, O., Nass, J., Ochwangi, D., Ooko, E., Ozenver, N., Saeed, M.E., Schneider, M., et al. Biopiracy of natural products and good bioprospecting practice. Phytomedicine 23 (2016), 166–173.
41. Efferth, T., Banjerjee, M., Hornung, A., Therapeutic intervention of post-traumatic stress disorder by Chinese medicine - perspectives for transdisciplinary cooperation between life sciences and humanities. Med. Stud., 2013, 10.1007/s12376-013-0085-4.
42. Efferth, T., Zacchino, S., Georgiev, M.I., Liu, L., Wagner, H., Panossian, A., Nobel Prize for artemisinin brings phytotherapy into the spotlight. Phytomedicine 22 (2015), A1–A3.
43. Eichhorn, T., Greten, H.J., Efferth, T., Self-medication with nutritional supplements and herbal over-the counter products. Nat. Prod. Bioprospect. 1 (2011), 62–70.
44. Efferth, T., Saeed, M.E.M., Mirghani, E., Alim, A., Yassin, Z., Saeed, E., Khalid, H.E., Daak, S., Integration of phytochemicals and phytotherapy into cancer precision medicine. Oncotarget 8 (2017), 50284–50304.
45. Ekeopara, C.A., Ugoha, A., The contributions of African traditional medicine to Nigeria's health care delivcery system. IOSR - J. Hum. Soc. Sci. 22 (2017), 32–43 http://www.iosrjournals.org/iosr-jhss/papers/Vol.%2022%20Issue5/Version-4/F2205043243.pdf (Accessed 17 June 2017).
46. Elumalai, A., Eswariah, M.C., Herbalism - a review. Int. J. Phytother. 2 (2012), 96–105.
47. Ernst, E., Hung, S.K., Great expectations: what do patients using complementary and alternative medicine hope for?. Patient 4 (2011), 89–101.
48. Esch, B.M., Marian, F., Busato, A., Heusser, P., Patient satisfaction with primary care: an observational study comparing anthroposophic and conventional care. Health Qual. Life Outcomes, 6, 2008, 74.
49. Franz, C., Chizzola, R., Novak, J., Sponza, S., Botanical species being used for manufacturing plant food supplements (PFS) and related products in the EU member states and selected third countries. Food Funct 2 (2011), 720–730.
50. Fong, H.H., Integration of herbal medicine into modern medical practices: issues and prospects. Integr. Cancer Ther. 1 (2002), 287–293 discussion 293.
51. Forest, F., Grenyer, R., Rouget, M., Davies, T.J., Cowling, R,M., Faith, D.P., Balmford, A., Manning, J.C., Proches, S., van der Bank, M., Reeves, G., Hedderson, T.A., Savolainen, V., Preserving the evolutionary potential of floras in biodiversity hotspots. Nature 445 (2007), 757–760.
52. Frenkel, M., Ben-Arye, E., Baldwin, C.D., Sierpina, V., Approach to communicating with patients about the use of nutritional supplements in cancer care. South Med. J. 98 (2005), 289–294.
53. Garrard, G., Ecocriticism: The New Critical Idiom. 2004, Routledge, New York.
54. Gandhi, S.G., Mahajan, V., Bedi, Y.S., Changing trends in biotechnology of secondary metabolism in medicinal and aromatic plants. Planta 241 (2015), 303–317.
55. Georgiev, M.I., Weber, J., Maciuk, A., Bioprocessing of plant cell cultures for mass production of targeted compounds. Appl. Microbiol. Biotechnol. 83 (2009), 809–823.
56. Gibney, M., Howard-Hassmann, R., Coicaud, J.-M., Steiner, N., The Age of Apology: Facing up the Past. 2008, University of Pennsylvania Press, Philadelphia.
57. Glisson, J.K., Walker, L.A., How physicians should evaluate dietary supplements. Am. J. Med. 123 (2010), 577–582.
58. Greten, H.J., Erhebung im Daomed Network. Gesundheitswirtschaftskongress, 2005.
59. Hakamatsuka, T., Marketing approval of ethical Kampo medicines. Yakugaku Zasshi 137 (2017), 163–165.
60. Guo, R., Zhang, X., Su, J., Xu, H., Zhang, Y., Zhang, F., Li, D., Zhang, Y., Xiao, X., Ma, S., Yang, H., Identifying potential quality markers of Xin-Su-Ning capsules acting on arrhythmia by integrating UHPLC-LTQ-Orbitrap, ADME prediction and network target analysis. Phytomedicine, 2018 [Epub ahead of print].
61. Hottenbacher, L., Weißhuhn, T.E., Watanabe, K., Seki, T., Ostermann, J., Witt, C.M., Opinions on Kampo and reasons for using it–results from a cross-sectional survey in three Japanese clinics. BMC Complement. Altern. Med., 13, 2013, 108.
62. Huggan, G., Tiffin, H., Postcolonial Ecocriticism: Literature, Animals, Environment. 2010, Routledge, New York.
63. Hunt, L.M., Arar, N.H., Akana, L.L., Herbs, prayer and insulin. Use of medicinal and alternative treatments by a group of Mexican American diabetes patients. J. Fam. Pract. 49 (2000), 216–223.
64. Jaski, M.E., Schwartzberg, J.G., Guttman, R.A., Noorani, M., Medication review and documentation in physician office practice. Eff. Clin. Pract. 3 (2000), 31–34.
65. Johnson, O., Venezuelan project establishes indigenous plant database. Br. Med. J., 325, 2002, 183.
66. Julsing, M.K., Koulman, A., Woerdenbag, H.J., Quax, W.J., Kayser, O., Combinatorial biosynthesis of medicinal plant secondary metabolites. Biomol. Eng. 23 (2006), 265–279.
67. Kadioglu, O., Jacob, S., Bohnert, S., Naß, J, Saeed, M.E., Khalid, H., Merfort, I., Thines, E., Pommerening, T., Efferth, T., Evaluating ancient Egyptian prescriptions today: anti-inflammatory activity of Ziziphus spina-christi. Phytomedicine 23 (2016), 293–306.
68. Kasilo, O.M.J., Trapsida, J.M., Mwikisa, C.N., Lusamba-Dikassa, P.S., An overview of the traditional medicine situation in the African region. Afr. Health Monitor 14 (2010), 7–15.
69. Keita, J.D., 1993. Non-wood forest products in Africa: an overview. Paper prepared for the Regional Expert Consultation on Non-wood forest products for English-speaking African Countries, Arusha, Tanzania, Council Commonwealth Science Council, 12 pp.
70. Khalid, H., Abdalla, W.E., Abdelgadir, H., Opatz, T., Efferth, T., Gems from traditional North-African medicine: medicinal and aromatic plants from Sudan. Nat. Prod. Bioprospect. 2 (2012), 92–103.
71. Klein, S.D., Torchetti, L., Frei-Erb, M., Wolf, U., Usage of complementary medicine in Switzerland: results of the Swiss Health Survey 2012 and development since 2007. PLoS One, 10, 2015, e0141985.
72. Klein, S.D., Frei-Erb, M., Wolf, U., Usage of complementary medicine across Switzerland: results of the Swiss Health Survey 2007. Swiss Med. Wkly., 142, 2007, w13666.
73. Kober, M., Pohl, K., Efferth, T., Molecular mechanisms underlying St. John's wort drug interactions. Curr. Drug Metab. 9 (2008), 1027–1037.
74. Kolewe, M.E., Gaurav, V., Roberts, S.C., Pharmaceutically active natural product synthesis and supply via plant cell culture technology. Mol. Pharm. 5 (2008), 243–256.
75. Kolodny, A., The Lay of the Land: Metaphors os Experience and History in American Life and Letters. 1975, University of North Carolina Press, Chapel Hill.
76. Latheef, S.A., Prasad, B., Bavaji, M., Subramanyam, G., A database on endemic plants at Tirumala hills in India. Bioinformation 2 (2008), 260–262.
77. Lazarou, J., Pomeranz, B.H., Corey, P.N., Incidence of adverse drug reactions in hospitalized patients: a meta-analysis of prospective studies. J. Am. Med. Assoc. 279 (1998), 1200–1205.
78. Lee, R.P., Comparative studies of health care systems. Soc. Sci. Med. 16 (2016), 629–642.
79. Li, K., Li, J., Su, J., Xiao, X., Peng, X., Liu, F., Li, D., Zhang, Y., Chong, T., Xu, H., Liu, C., Yang, H., Identification of quality markers of Yuanhu Zhitong tablets based on integrative pharmacology and data mining. Phytomedicine, 2018 [Epub ahead of print].
80. Li, X.Q., Yang, J.N., Su, Y.H., [Does the utilization of traditional Chinese herbs threaten the biodiversity?]. Zhong Xi Yi Jie He Xue Bao 5 (2007), 363–367.
81. Liao, M., Shang, H., Li, Y., Li, T., Wang, M., Zheng, Y., Hou, W., Liu, C., An integrated approach to uncover quality marker underlying the effects of Alisma orientale on lipid metabolism, using chemical analysis and network pharmacology. Phytomedicine, 2018 [Epub ahead of print].
82. Liao, Y.H., Lin, C.C., Li, T.C., Lin, J.G., Utilization pattern of traditional Chinese medicine for liver cancer patients in Taiwan. BMC Complement. Altern. Med., 12, 2012, 146.
83. Liao, Y.H., Lin, J.G., Lin, C.C., Li, T.C., Distributions of usage and the costs of conventional medicine and traditional Chinese medicine for lung cancer patients in taiwan. Evid. Based Complement. Alternat. Med., 2013, 984876 2013.
84. Lim, J.M., Sullivan, E., Kennedy, D., MotherSafe: review of three years of counselling by an Australian Teratology Information Service. Aust. N. Z. J. Obstet. Gynaecol. 49 (2009), 168–172.
85. Lim, S.M., Syn, N.L., Cho, B.C., Soo, R.A., Acquired resistance to EGFR targeted therapy in non-small cell lung cancer: mechanisms and therapeutic strategies. Cancer Treat. Rev. 65 (2018), 1–10.
86. Liu, M.Z., Zhang, Y.L., Zeng, M.Z., He, F.Z., Luo, Z.Y., Luo, J.Q., Wen, J.G., Chen, X.P., Zhou, H.H., Zhang, W., Pharmacogenomics and herb-drug interactions: merge of future and tradition. Evid. Based Complement. Alternat. Med., 2015, 2015, 321091.
87. Lu, J., Zhang, Y., Sun, M., Liu, M., Wang, X., Comprehensive assessment of Cucurbitacin E related hepatotoxicity and drug-drug interactions involving CYP3A and P-glycoprotein. Phytomedicine 26 (2017), 1–10.
88. Maegawa, H., Nakamura, T., Saito, K., Regulation of traditional herbal medicinal products in Japan. J. Ethnopharmacol., 2014, 511–515 158 Pt B.
89. Maimer, A., Remppis, A., Sack, F.U., Ringes-Lichtenberg, S., Greten, T., Brazkiewicz, F., Schröder, S., Goncalves, M., Efferth, T., Greten, H.J., Objectifying acupuncture effects by lung function and numeric rating scale in patients undergoing heart surgery. Evid.-Based Complement. Alternat. Med., 2013, 2013, 219817.
90. May, J., What is integrative health?. Br. Med. J., 343, 2011, d4372.
91. Mbatha, N., Street, R.A., Ngcobo, M., Gqaleni, N., Sick certificates issued by South African traditional health practitioners: current legislation, challenges and the way forward. S. Afr. Med. J. 102 (2012), 129–131.
92. Mehrotra, S., Srivastava, V., Ur Rahman, L., Kukreja, A.K., Hairy root biotechnology–indicative timeline to understand missing links and future outlook. Protoplasma 252 (2015), 1189–1201.
93. Meng, Q, Liu, K., Pharmacokinetic interactions between herbal medicines and prescribed drugs: focus on drug metabolic enzymes and transporters. Curr. Drug Metab. 15 (2014), 791–807.
94. Meyer-Hamme, G., Friedemann, T., Greten, H.J., Plaetke, R., Gerloff, C., Schroeder, S., ACUDIN - ACUpuncture and laser acupuncture for treatment of diabetic peripheral neuropathy: a randomized, placebo-controlled, partially double-blinded trial. BMC Neurol, 18, 2018, 40.
95. Ministério do Meio Ambiente (MAA). Portal Brasileiro sobre Biodiversidade – PortalBio/MMA. www.mma.gov.br/portalbio, 2011.
96. Mitty, E., Flores, S., Assisted living nursing practice: medication management: Part 1. Assessing the resident for self-medication ability. Geriatr. Nurs. 28 (2007), 83–89.
97. Moschik, E.C., Mercado, C., Yoshino, T., Matsuura, K., Watanabe, K., Usage and attitudes of physicians in Japan concerning traditional Japanese medicine (kampo medicine): a descriptive evaluation of a representative questionnaire-based survey. Evid. Based Complement. Alternat. Med., 2012, 2012, 139818.
98. Muntendam, R., Melillo, E., Ryden, A., Kayser, O., Perspectives and limits of engineering the isoprenoid metabolism in heterologous hosts. Appl. Microbiol. Biotechnol. 84 (2009), 1003–1019.
99. Newman, E.B., Earth's vanishing medicine cabinet: rain forest destruction and its impact on the pharmaceutical industry. Am. J. Law Med. 20 (1994), 479–501.
100. Newman, D.J., Cragg, G.M., Natural products as sources of new drugs over the 30 years from 1981 to 2010. J. Nat. Prod. 75 (2012), 11–35.
101. No authors. What happened to personalized medicine?. Nat. Biotechnol., 30, 2012, 1.
102. Paul, N.W., Roses, A.D., Pharmacogenetics and Pharmacogenomics: recent developments, their clinical relevance and some ethical, social, and legal implications. J. Mol. Med. 81 (2003), 135–140.
103. Ochwang'i, D.O., Oduma, J.A., Chapter 6 – Overview of governmental support across Africa toward the development and growth of herbal medicine. Kuete, V., (eds.) Medicinal Spices and Vegetables from Africa Therapeutic Potential against Metabolic, Inflammatory, Infectious and Systemic Diseases, 2017, Elsevier, London, San Diego, Cambridge, Oxford, 153–169.
104. Ogita, S., Plant cell, tissue and organ culture: the most flexible foundations for plant metabolic engineering applications. Nat. Prod. Commun 10 (2015), 815–820.
105. OneWorldHealth, 2016. OneWorldHealth. http://www.OneWorldHealth.com (Accessed 17 June 2017).
106. Osathanunkul, M., Suwannapoom, C., Osathanunkul, K., Madesis, P., de Boer, H., Evaluation of DNA barcoding coupled high resolution melting for discrimination of closely related species in phytopharmaceuticals. Phytomedicine 23 (2016), 156–165.
107. Oyebode, O., Kandala, N.B., Chilton, P.J., Lilford, R.J., Use of traditional medicine in middle-income countries: a WHO-SAGE study. Health Policy Plan 31 (2016), 984–991.
108. Patel, A.B., O'Hare, T., Deininger, M.W., Mechanisms of resistance to ABL kinase inhibition in chronic myeloid leukemia and the development of next generation ABL kinase inhibitors. Hematol. Oncol. Clin. North Am. 31 (2017), 589–612.
109. Poornima, P., Kumar, J.D., Zhao, Q., Blunder, M., Efferth, T., Network pharmacology of cancer: from understanding of complex interactomes to the design of multi-target specific therapeutics from nature. Pharmacol. Res. 111 (2016), 290–302.
110. Posadzki, P., Watson, L., Ernst, E., Contamination and adulteration of herbal medicinal products (HMPs): an overview of systematic reviews. Eur. J. Clin. Pharmacol. 69 (2013), 295–307.
111. Puoane, T.R., Hughes, G.D., Uwimana, J., Johnson, Q., Folk, W.R., Why HIV positive patients on antiretroviral treatment and/or cotrimoxazole prophylaxis use traditional medicine: perceptions of health workers, traditional healers and patients: a study in two provinces of South Africa. Afr. J. Tradit. Complement. Altern. Med. 9 (2012), 495–502.
112. Quattropani, C., Ausfeld, B., Straumann, A., Heer, P., Seibold, F., Complementary alternative medicine in patients with inflammatory bowel disease: use and attitudes. Scand. J. Gastroenterol. 38 (2003), 277–282.
113. Rolfes, L., Van Hunsel, F., Van Der Linden, L., Taxis, K., van Puijenbroek, E., The quality of clinical information in adverse drug reaction reports by patients and healthcare professionals: a retrospective comparative analysis. Drug Safety 40 (2017), 607–614.
114. Ruiz, M.E., Risks of self-medication practices. Curr. Drug Safety 5 (2010), 315–323.
115. Sahebkar, A., Gurban, C., Serban, A., Andrica, F., Serban, M.C., Effects of supplementation with pomegranate juice on plasma C-reactive protein concentrations: a systematic review and meta-analysis of randomized controlled trials. Phytomedicine 23 (2016), 1095–1102.
116. Schmid, G., Hofheinz, W., Total synthesis of qinghaosu. J. Am. Chem. Soc. 105 (1983), 624–625.
117. Schmidt, F., Efferth, T., Tumor heterogeneity, single-cell sequencing, and drug resistance. Pharmaceuticals (Basel), 9, 2016 pii:E33.
118. Schnabel, K., Binting, S., Witt, C.M., Teut, M., Use of complementary and alternative medicine by older adults - a cross-sectional survey. BMC Geriatr, 14, 2014, 38.
119. Schwarz, S., Messerschmidt, H., Völzke, H., Hoffmann, W., Lucht, M., Dören, M., Use of complementary medicinal therapies in West Pomerania: a population-based study. Climacteric 11 (2008), 124–134.
120. Schwingshackl, L., Missbach, B., Hoffmann, G., An umbrella review of garlic intake and risk of cardiovascular disease. Phytomedicine 23 (2016), 1127–1133.
121. Sharad, S., Manish, P., Mayank, B., Mitul, C., Sanjay, S., Regulatory status of traditional medicines in Africa regions. Int. J. Res. Ayurveda Pharmacy 2011 2:1 (2011), 103–110 http://www.ijrap.net/issue-three/103-110.pdf (Accessed 17 June 2017).
122. Shaw, D., Graeme, L., Pierre, D., Elizabeth, W., Kelvin, C., Pharmacovigilance of herbal medicine. J. Ethnopharmacol. 140 (2012), 513–518.
123. Shiva, V., Biopiracy: The Plunder of Nature and Knowledge. 1997, South End Press, New York.
124. Snyderman, R., Weil, A.T., Integrative medicine: bringing medicine back to its roots. Arch. Intern. Med. 162 (2002), 395–397.
125. Singh, D.K., Cheema, H.S., Saxena, A., Jyotshana, Singh, S., Darokar, M.P., Bawankule, D.U., Shanker, K., Luqman, S., Fraxetin and ethyl acetate extract from Lawsonia inermis L. ameliorate oxidative stress in P. berghei infected mice by augmenting antioxidant defence system. Phytomedicine 36 (2017), 262–272.
126. Sousa, C.M., Coimbra, D., Machado, J., Greten, H.J., Effects of self-administered exercises based on Tuina techniques on musculoskeletal disorders of professional orchestra musicians: a randomized controlled trial. J. Integr. Med. 13 (2015), 314–318.
127. Srivastava, J., Lambert, J., Vietmayer, N., Medicinal Plants. An Expanding Role in Development. 1996, World Bank Technical Paper No. 320, Washington, D.C.
128. Szpilman, A.M., Carreira, E.M., Probing the biology of natural products: molecular editing by diverted total synthesis. Angew. Chem. Int. Ed. Engl. 49 (2010), 9592–9628.
129. Tomé-Carneiro, J., Visioli, F., Polyphenol-based nutraceuticals for the prevention and treatment of cardiovascular disease: review of human evidence. Phytomedicine 23 (2016), 1145–1174.
130. Tiran, D., Integrated healthcare: herbal remedies for menopausal symptoms. Br. J. Nurs. 15 (2006), 645–648.
131. Ulrich-Merzenich, G., Hartbrod, F., Kelber, O., Müller, J., Koptina, A., Zeitler, H., Salicylate-based phytopharmaceuticals induce adaptive cytokine and chemokine network responses in human fibroblast cultures. Phytomedicine 34 (2017), 202–211.
132. Verpoorte, R., Choi, Y.H., Kim, H.K., Ethnopharmacology and systems biology: a perfect holistic match. J. Ethnopharmacol. 100 (2005), 53–56.
133. Volm, M., Efferth, T., Prediction of cancer drug resistance and implications for personalized medicine. Front. Oncol., 5, 2015, 282.
134. Vora, C.K., Mansoor, G.A., Herbs and alternative therapies: relevance to hypertension and cardiovascular diseases. Curr. Hypertens. Rep. 7 (2005), 275–280.
135. Wagner, H., Efferth, T., Introduction: Novel hybrid combinations containing synthetic or antibiotic drugs with plant-derived phenolic or terpenoid compounds. Phytomedicine 37 (2017), 1–3.
136. Wolf, U., Maxion-Bergemann, S., Bornhöft, G., Matthiessen, P.F., Wolf, M., Use of complementary medicine in Switzerland. Forsch. Komplementmed 13:2 (2006), 4–6 Suppl.
137. World Health Organization, 1978. Alma Ata Declaration Primary Health Care. Health for all series No. 1. http://www.who.int/publications/almaata_declaration_en.pdf (Accessed 17 June 2017).
138. World Health Organization. WHO quality control methods for herbal materials. https://de.scribd.com/document/151544729/WHO, 1998.
139. World Health Organization. General guidelines for methodologies on research and evaluation of traditional medicine. WHO, ed. http://appswhoint/iris/bitstream/10665/66783/1/WHO_EDM_TRM_20001pdf, 2000.
140. World Health Organization. Promoting the Role of Traditional Medicine in Health Systems: A Strategy For the African Region. 2001, WHO Regional Office for Africa, Temporary location, Harare, Zimbabwe Document AFR/RC50/9 and resolution AFR/RC50/R3.
141. World Health Organization. The health of indigenous people. http://wwwwhoint/mediacentre/factsheets/fs326/en/, 2007.
142. World Health Organization. WHO traditional medicine strategy: 2014– 2023. http://appswhoint/iris/bitstream/10665/92455/1/9789241506090_eng.pdf, 2013.
143. Wu, M., Lu, P., Shi, L., Li, S., Traditional Chinese patent medicines for cancer treatment in China: a nationwide medical insurance data analysis. Oncotarget 6 (2015), 38283–38295.
144. Woo, H.J., Kim, H.Y., Choi, E.S., Cho, Y.H., Kim, Y., Lee, J.H., Jang, E., Drug-induced liver injury: a 2-year retrospective study of 1169 hospitalized patients in a single medical center. Phytomedicine 22 (2015), 1201–1205.
145. Yesilada, E., Sezik, E., Survey on the traditional medicine of Turkey: semiquantitative evaluation of the results. Singh, V.K., Govil, J.N., Hashmi, S., Singh, G., (eds.) Recent Progress in Medicinal Plants. Ethnomedicine and Pharmacognosy II, 7, 2003, Studium Press, LLC, Houston, TX, 389–412.
146. Yusuff, K.B., Tayo, F., Frequency, types and severity of medication use-related problems among medical outpatients in Nigeria. Int. J. Clin. Pharm. 33 (2011), 558–564.
147. Zaenker, K.S., Entschladen, F., Paving roads for new drugs in oncology. Recent Pat. Anticancer Drug Discov. 4 (2009), 137–145.
148. Zeng, Q., Qiu, F., Yuan, L., Production of artemisinin by genetically-modified microbes. Biotechnol. Lett. 30 (2008), 581–592.
149. Zeng, L., Zou, Y., Kong, L., Wang, N., Wang, Q., Wang, L., Cao, Y., Wang, K., Chen, Y., Mi, S., Zhao, W., Wu, H., Cheng, S., Xu, W., Liang, W., Can Chinese herbal medicine adjunctive therapy improve outcomes of senile vascular dementia? Systematic review with meta-analysis of clinical trials. Phytother. Res. 29 (2015), 1843–1857.
150. Zhang, B., Peng, Y., Zhang, Z., Liu, H., Qi, Y., Liu, S., Xiao, P., GAP production of TCM herbs in China. Planta Med 76 (2010), 1948–1955.
151. Zhang, L., Yan, J., Liu, X., Ye, Z., Yang, X., Meyboom, R., Chan, K., Shaw, D., Duez, P., Pharmacovigilance practice and risk control of Traditional Chinese Medicine drugs in China: current status and future perspective. J. Ethnopharmacol. 140 (2012), 519–525.
152. Zuo, Z., Huang, M., Kanfer, I., Chow, M.S., Cho, W.C., Herb-drug interactions: systematic review, mechanisms, and therapies. Evid. Based Complement. Alternat. Med., 2015, 2015, 239150.