An integrated approach to uncover quality marker underlying the effects of Alisma orientale on lipid metabolism, using chemical analysis and network pharmacology

Phytomedicine

Volumn 45, Issue , 2018, Pages 93-104

  Liao, Maoliang ^a,b   Shang, Haihua ^a   Li, Yazhuo ^b   Li, Tian ^c   Wang, Miao ^b   Zheng, Yanan ^b   Hou, Wenbin ^b   Liu, Changxiao ^a,b  

^a SHENYANG PHARMACEUTICAL UNIVERSITY   (China)

^b TIANJIN INSTITUTE OF PHARMACEUTICAL RESEARCH   (China)

^c TIANJIN UNIVERSITY OF TRADITIONAL CHINESE MEDICINE   (China)

Author keywords

Alisma orientale; Network pharmacology; Q marker; Quality control

Indexed keywords

11 DEOXYALISOL B; 13,17 EPOXY ALISOL A; 13,17 EPOXY ALISOL A 24 ACETATE; 13,17 EPOXY ALISOL B 24 ACETATE; 16 HYDROXY ALISOL A; 16 OXO 11 ANHYDRO ALISOL A; 16 OXO 11 DEOXY ALISOL A; 16 OXO ALISOL A; 16 OXO ALISOL A 23 ACETATE; 16 OXO ALISOL A 24 ACETATE; 16,23 EPOXY ALISOL B; ALISMA ORIENTALE EXTRACT; ALISOL A; ALISOL A 23 ACETATE; ALISOL A 24 ACETATE; ALISOL B; ALISOL B 23 ACETATE; ALISOL C; ALISOL C 23 ACETATE; ALISOL D; ALISOL F; ALISOL G; ALISOL L 24 ACETATE; ALISOL M 23 ACETATE; ANTILIPEMIC AGENT; ANTIOXIDANT; DRUG METABOLITE; PLANT EXTRACT; PLANT MEDICINAL PRODUCT; SIMVASTATIN; UNCLASSIFIED DRUG; ALISOL A 24-ACETATE; ALISOL B 23-ACETATE; CHOLEST 4 EN 3 ONE; HERBACEOUS AGENT; PHARMACOLOGICAL BIOMARKER;

ABTS RADICAL SCAVENGING ASSAY; ALISMA; ALISMA ORIENTALE; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIOXIDANT ACTIVITY; ARTICLE; BIOSYNTHESIS; CHEMICAL ANALYSIS; CHEMICAL COMPOSITION; CONTROLLED STUDY; DPPH RADICAL SCAVENGING ASSAY; DRUG DOSE COMPARISON; DRUG EFFICACY; DRUG MECHANISM; DRUG MEGADOSE; ETHNOPHARMACOLOGY; EVALUATION STUDY; HEP-G2 CELL LINE; HERBAL MEDICINE; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HUMAN; HUMAN CELL; HYPERLIPIDEMIA; IN VITRO STUDY; ION TRAP MASS SPECTROMETRY; LIPID METABOLISM; LIPID STORAGE; LIQUID CHROMATOGRAPHY-MASS SPECTROMETRY; LOW DRUG DOSE; MALE; NETWORK PHARMACOLOGY; NONHUMAN; PHARMACOLOGY; PRIORITY JOURNAL; QUALITY CONTROL; RAT; TIME OF FLIGHT MASS SPECTROMETRY; ANIMAL; CHEMISTRY; CHINESE MEDICINE; DRUG EFFECT; STANDARDS; WISTAR RAT;

ALISMA; ANIMALS; BIOMARKERS, PHARMACOLOGICAL; CHOLESTENONES; DRUGS, CHINESE HERBAL; HEP G2 CELLS; HUMANS; HYPOLIPIDEMIC AGENTS; LIPID METABOLISM; MALE; MEDICINE, CHINESE TRADITIONAL; PLANT EXTRACTS; RATS, WISTAR;

EID: 85046142487     PISSN: 09447113     EISSN: 1618095X     Source Type: Journal    
DOI: 10.1016/j.phymed.2018.04.006     Document Type: Article

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