Directed strain evolution restructures metabolism for 1-butanol production in minimal media

Metabolic Engineering

Volumn 49, Issue , 2018, Pages 153-163

  Pontrelli, Sammy ^a   Fricke, Riley C B ^a   Sakurai, Sana Subhan Memon ^b   Putri, Sastia Prama ^b   Fitz Gibbon, Sorel ^c   Chung, Matthew ^a   Wu, Hsin Yi ^d   Chen, Yu Ju ^e   Pellegrini, Matteo ^c   Fukusaki, Eiichiro ^b   Liao, James C ^f  

^a Engineering IV   (United States)

^b OSAKA UNIVERSITY   (Japan)

^c UNIVERSITY OF CALIFORNIA   (United States)

^d NATIONAL TAIWAN UNIVERSITY   (Taiwan)

^e INSTITUTE OF CHEMISTRY   (Taiwan)

^f INSTITUTE OF BIOLOGICAL CHEMISTRY   (Taiwan)

Author keywords

[No Author keywords available]

Indexed keywords

CYTOLOGY; ENZYMES; ESCHERICHIA COLI; MOLECULAR BIOLOGY; PHYSIOLOGY; RATIONAL FUNCTIONS; REPAIR;

BIOSYNTHETIC PATHWAY; BY-PRODUCT FORMATION; INTEGRATION HOST FACTOR; METABOLIC FUNCTION; MICROBIAL PRODUCTION; PHYSIOLOGICAL PROCESS; RESOURCE UTILIZATIONS; TWO COMPONENT SYSTEMS;

METABOLISM;

6 PHOSPHOFRUCTOKINASE; ACETYL COENZYME A; BACTERIAL DNA; BACTERIAL RNA; BUTANOL; FORMATE DEHYDROGENASE; GENOMIC DNA; GLUCOSE 6 PHOSPHATE DEHYDROGENASE; GLUCOSE 6 PHOSPHATE ISOMERASE; GLYCERALDEHYDE 3 PHOSPHATE DEHYDROGENASE; GLYCOLYTIC ENZYME; INTEGRATION HOST FACTOR; NICOTINAMIDE ADENINE DINUCLEOTIDE; PHOSPHATE ACETYLTRANSFERASE; PHOSPHOGLYCERATE KINASE; PHOSPHOGLYCERATE MUTASE; TRIOSEPHOSPHATE ISOMERASE; UNTRANSLATED RNA; ESCHERICHIA COLI PROTEIN; PCNB PROTEIN, E COLI; POLYNUCLEOTIDE ADENYLYLTRANSFERASE;

ARTICLE; BACTERIAL GROWTH; BACTERIAL MUTATION; BACTERIAL STRAIN; BIOSYNTHESIS; CARBON STORAGE; CELL FUNCTION; CELL METABOLISM; CONTROLLED STUDY; ENZYME ACTIVITY; ESCHERICHIA COLI; EVOLUTION; FERMENTATION; GENOMICS; METABOLIC ENGINEERING; METABOLOMICS; NONHUMAN; PHENOTYPE; POINT MUTATION; PRIORITY JOURNAL; PROTEOMICS; CLOSTRIDIUM; DIRECTED MOLECULAR EVOLUTION; GENETICS; METABOLISM; TRANSGENIC MICROORGANISM;

1-BUTANOL; CLOSTRIDIUM; DIRECTED MOLECULAR EVOLUTION; ESCHERICHIA COLI; ESCHERICHIA COLI PROTEINS; MICROORGANISMS, GENETICALLY-MODIFIED; POLYNUCLEOTIDE ADENYLYLTRANSFERASE;

EID: 85051681740     PISSN: 10967176     EISSN: 10967184     Source Type: Journal    
DOI: 10.1016/j.ymben.2018.08.004     Document Type: Article

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