Gut microbiota dysbiosis is associated with malnutrition and reduced plasma amino acid levels: Lessons from genome-scale metabolic modeling

Metabolic Engineering

Volumn 49, Issue , 2018, Pages 128-142

  Kumar, Manish ^a   Ji, Boyang ^a   Babaei, Parizad ^a   Das, Promi ^a   Lappa, Dimitra ^a   Ramakrishnan, Girija ^e   Fox, Todd E ^e   Haque, Rashidul ^f   Petri, William A ^e   Bäckhed, Fredrik ^c,d   Nielsen, Jens ^a,b  

^a CHALMERS UNIVERSITY OF TECHNOLOGY   (Sweden)

^b Chalmers University of Technology   (Denmark)

^c UNIVERSITY OF GOTHENBURG   (Sweden)

^d Capital Region   (Denmark)

^e UNIVERSITY OF VIRGINIA   (United States)

^f INTERNATIONAL CENTRE FOR DIARRHOEAL DISEASE RESEARCH   (Bangladesh)

Author keywords

Bacterial interactions; Child malnutrition; Genome scale metabolic modeling; Gut microbiota; Metabolic capabilities; Plasma metabolic profiling

Indexed keywords

AMINO ACIDS; BACTERIA; GENES; NUTRITION;

BACTERIAL INTERACTIONS; CHILD MALNUTRITION; GENOME SCALE METABOLIC MODEL; GUT MICROBIOTA; METABOLIC CAPABILITIES; METABOLIC PROFILING;

METABOLISM;

2 AMINOBUTYRIC ACID; AMINO ACID DERIVATIVE; ARGININE; ESSENTIAL AMINO ACID; GLUTAMINE; GLYCINE; HISTIDINE; ISOLEUCINE; KYNURENINE; LEUCINE; METHIONINE; NONESSENTIAL AMINO ACID; PHENYLALANINE; PROLINE; SERINE; THREONINE; TRYPTAMINE; TRYPTOPHAN; TYROSINE; VALINE; AMINO ACID;

AMINO ACID BLOOD LEVEL; ARTICLE; BACTERIAL GENOME; BACTERIAL GROWTH; BACTEROIDES THETAIOTAOMICRON; BIFIDOBACTERIUM ADOLESCENTIS; CHILD; COMPARATIVE STUDY; CONTROLLED STUDY; DISEASE ASSOCIATION; DYSBIOSIS; EUBACTERIUM; EUBACTERIUM RECTALE; FAECALIBACTERIUM PRAUSNITZII; FEMALE; HIGH INCOME COUNTRY; HUMAN; INFANT; INTESTINE FLORA; LOW INCOME COUNTRY; MAJOR CLINICAL STUDY; MALE; MALNUTRITION; METABOLITE; METABOLOMICS; MICROBIAL COMMUNITY; MICROBIAL DIVERSITY; NEWBORN; NONHUMAN; ORGANISMAL INTERACTION; PREVOTELLA; PREVOTELLA COPRI; PRIORITY JOURNAL; ROSEBURIA INULINIVORANS; STUNTING; BLOOD; GENETICS; MICROBIOLOGY; NUTRITIONAL DISORDER; PRESCHOOL CHILD;

AMINO ACIDS; CHILD; CHILD NUTRITION DISORDERS; CHILD, PRESCHOOL; DYSBIOSIS; FEMALE; GASTROINTESTINAL MICROBIOME; GENOME, BACTERIAL; HUMANS; MALE;

EID: 85051385729     PISSN: 10967176     EISSN: 10967184     Source Type: Journal    
DOI: 10.1016/j.ymben.2018.07.018     Document Type: Article

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